• As a polar head group, phosphatidylethanolamine creates a more viscous lipid membrane compared to phosphatidylcholine. (wikipedia.org)
  • For example, the melting temperature of di-oleoyl-phosphatidylethanolamine is -16 °C while the melting temperature of di-oleoyl-phosphatidylcholine is -20 °C. If the lipids had two palmitoyl chains, phosphatidylethanolamine would melt at 63 °C while phosphatidylcholine would melt already at 41 °C. Lower melting temperatures correspond, in a simplistic view, to more fluid membranes. (wikipedia.org)
  • The synthesis of endocannabinoid anandamide is performed from the phosphatidylethanolamine by the successive action of 2 enzymes, the N-acetyltransferase and phospholipase-D. Where phosphatidylcholine is the principal phospholipid in animals, phosphatidylethanolamine is the principal one in bacteria. (wikipedia.org)
  • Whereas the phosphate group is combined with choline in phosphatidylcholine, it is combined with ethanolamine in phosphatidylethanolamine. (wikipedia.org)
  • In a process that mirrors phosphatidylcholine synthesis, phosphatidylethanolamine is also made via the cytidine diphosphate-ethanolamine pathway, using ethanolamine as the substrate. (wikipedia.org)
  • LPA is a membrane-derived lysophospholipid from phosphatidylcholine (PC), phosphatidylserine (PS), and phosphatidylethanolamine (PE) [ 7 ]. (hindawi.com)
  • Phosphatidylethanolamine is also thought to play a role in blood clotting, as it works with phosphatidylserine to increase the rate of thrombin formation by promoting binding to factor V and factor X, two proteins which catalyze the formation of thrombin from prothrombin. (wikipedia.org)
  • The phosphatidylserine decarboxylation pathway and the cytidine diphosphate-ethanolamine pathways are used to synthesize phosphatidylethanolamine. (wikipedia.org)
  • The phosphatidylserine decarboxylation pathway is the main source of synthesis for phosphatidylethanolamine in the membranes of the mitochondria. (wikipedia.org)
  • Phosphatidylethanolamine (PE) is frequently the main lipid component of microbial membranes and the second most abundant phospholipid in mammals, comprising as much as 45% of brain lipids. (matreya.com)
  • Surprisingly, bacteria in the stationary phase produced N-acyl-phosphatidylethanolamine (NAPE) and another rare lipid we tentatively name as 1-phosphatidyl-2-acyl-glycero-3-phosphoethanolamine (PAGPE) based on tandem mass spectrometry. (nature.com)
  • NAPEPLD is a phospholipase D type enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE) in the second step of the biosynthesis of N-acylethanolamine (Okamoto et al. (novusbio.com)
  • While CL increases, the two predominant lipids phosphatidylglycerol (PG) and phosphatidylethanolamine (PE) of the exponential growth phase decrease as B. subtilis enters stationary phase 6 . (nature.com)
  • Phosphatidylethanolamine produced in the mitochondrial membrane is also transported throughout the cell to other membranes for use. (wikipedia.org)
  • Phosphatidylethanolamine is the second most abundant phospholipid in mammalian cells. (alfa-chemistry.com)
  • Phosphatidylethanolamine is a non-bilayer formed phospholipid containing small polar heads proportional to the diameter of its fatty acid chain. (alfa-chemistry.com)
  • Concurrent decrease in phosphatidylethanolamine content from 23% of total phospholipid to 7%, accumulation of 14C-PL to 2.6% of total phospholipid, and increase in lysophosphatidylethanolamine from 1 to 7% of total phospholipid durkng 2-hexanone + 14CHCl3 treatment indicated that the amine moiety of phosphatidylethanolamine polar head groups was the probable target of phosgene -lipid interaction, and that a degradative pathway existed which removed the abnormal phospholipid from hepatic membranes. (cdc.gov)
  • No phospholipid other than phosphatidylethanolamine was depleted. (cdc.gov)
  • Phosphatidylethanolamine is an important precursor, substrate, or donor in several biological pathways. (wikipedia.org)
  • Phosphatidylethanolamine-binding protein is the precursor of hippocampal cholinergic neurostimulating peptide, which is cleaved from the N-terminal region of the protein. (bvsalud.org)
  • In humans, metabolism of phosphatidylethanolamine is thought to be important in the heart. (wikipedia.org)
  • Phosphatidylethanolamine metabolism in health and disease. (alfa-chemistry.com)
  • Additionally, it is thought that phosphatidylethanolamine regulates membrane curvature. (wikipedia.org)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Phosphatidylethanolamine Binding Protein 1 (PEBP1) in tissue homogenates, cell lysates and other biological fluids. (marchforscienceshop.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Phosphatidylethanolamine Binding Protein 1 (PEBP1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (marchforscienceshop.com)
  • Description: A sandwich ELISA kit for detection of Phosphatidylethanolamine Binding Protein 1 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (marchforscienceshop.com)
  • Results: Increased concentrations of beta-synuclein, gamma-synuclein, neurogranin, phosphatidylethanolamine-binding protein 1, and 14-3-3 proteins were observed in AD patients compared to controls, while neuronal pentraxin-2 and. (lu.se)
  • A ubiquitously found basic protein that binds to phosphatidylethanolamine and NUCLEOTIDES. (bvsalud.org)
  • Phosphatidylethanolamines interact with a wide range of proteins, thus influencing biological processes such as neuronal development or signaling pathways. (lipotype.com)
  • Phosphatidylethanolamine has also shown to be able to propagate infectious prions without the assistance of any proteins or nucleic acids, which is a unique characteristic of it. (wikipedia.org)
  • Phosphatidylethanolamine series are important excipients for nucleic acid delivery. (alfa-chemistry.com)
  • During model studies, 12% phosgene in toluene was reacted with liver phosphatidylethanolamine for 6 hr at 37 degrees C. Two reaction products were formed, further substantiating that phosphatidylethanolamine (PE) may react with [14C] phosgene in liver. (cdc.gov)
  • Alfa Chemistry supplies a wide range of phosphatidylethanolamine products for companies researching vaccines. (alfa-chemistry.com)
  • Phosphatidylethanolamines play a role in membrane fusion and in disassembly of the contractile ring during cytokinesis in cell division. (wikipedia.org)
  • In the bacterium E. coli, phosphatidylethanolamine play a role in supporting lactose permeases active transport of lactose into the cell, and may play a role in other transport systems as well. (wikipedia.org)
  • When phosphatidylethanolamine is not present, the transport proteins have incorrect tertiary structures and do not function correctly. (wikipedia.org)
  • Phosphatidylethanolamine also enables bacterial multidrug transporters to function properly and allows the formation of intermediates that are needed for the transporters to properly open and close. (wikipedia.org)
  • When blood flow to the heart is restricted, the asymmetrical distribution of phosphatidylethanolamine between membrane leaflets is disrupted, and as a result the membrane is disrupted. (wikipedia.org)