• stimulation
  • T cells within the CCR7 + "central-memory" T cell (T CM cell) cell subset show hypo-acetylated cytokine genes and have no or low effector functions, but efficiently differentiate to Th1 or Th2 effector cells after TCR stimulation in the presence of IL-12 or IL-4, respectively ( 12 - 14 ). (rupress.org)
  • In contrast, T cells of the CCR7 − "effector-memory" T cell (T EM cell) subset show polarized cytokine gene acetylation patterns in vivo and rapidly produce high amounts of IFN-γ and IL-4 upon antigenic stimulation ( 12 - 14 ). (rupress.org)
  • Plating onto basement membrane matrix and stimulation by phorbol ester were used as in vitro models of angiogenesis. (bmj.com)
  • Isoliert wurde die T-Zellpopulation CD 4 und CD 8 der Lymphozyten untersucht Eine intrazytoplasmatische Zytokinbestimmung nach Stimulation mit Ionomycin und Phorbol-12,13-Dibutyrat unter Verwendung von Monensin wurde durchgeführt. (hu-berlin.de)
  • robust
  • In a canine double-hemorrhage model, the membrane translocation of PKC from cytosol in the basilar artery was observed after the second injection of autologous blood on the 4th day when vasospasm was robust [ 10 , 12 ]. (hindawi.com)
  • activity
  • Consistent with the activity of the lipophilic derivatives being masked by an inability to transfer from the aqueous to the lipid phase, phorbol 12,13-distearate added to the aqueous phase inhibited efficiently (apparent inhibitor equilibrium dissociation constant, 14 n M ) in the presence of 0.03% Triton X-100. (aacrjournals.org)