• Phenyl Hydrazine, also known as phenylhydrazine hydrochloride, is a chemical compound used in the production of dyes, pharmaceuticals, and photographic materials. (marcorubber.com)
  • Spectrumâ„¢ Chemical Phenylhydrazine Hydrochloride, Crystal, Reagent , also known as Hydrazinobenzene, is used to prepare indoles by way of the Fischer Indole Synthesis. (fishersci.com)
  • Phenylhydrazine was the first hydrazine derivative characterized, reported by Hermann Emil Fischer in 1875. (wikipedia.org)
  • Maximum permissible concentrations of hydrazine hydrate and phenylhydrazine in water bodies. (cdc.gov)
  • A personal pump sampling method was tested for monitoring hydrazine (302012), 1,1-dimethylhydrazine (57147), phenylhydrazine (100630), and monomethylhydrazine (60344) vapors. (cdc.gov)
  • Recovery rates of over 90 percent were obtained for hydrazine , 1,1-dimethylhydrazine, and phenylhydrazine, but only 75 to 84 percent was obtained for monomethylhydrazine. (cdc.gov)
  • NIOSH considers phenylhydrazine to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990]. (cdc.gov)
  • Defense of mouse red blood cells against oxidative damage by phenylhydrazine. (utmb.edu)
  • Dive into the research topics of 'Defense of mouse red blood cells against oxidative damage by phenylhydrazine. (utmb.edu)
  • Phenylhydrazine is prepared by oxidizing aniline with sodium nitrite in the presence of hydrogen chloride to form the diazonium salt, which is subsequently reduced using sodium sulfite in the presence of sodium hydroxide to form the final product. (wikipedia.org)
  • Zinc dust and alcoholic acetic acid reduce it to aniline and phenylhydrazine . (dictionary.com)
  • No inhalation toxicity data are available on which to base an IDLH for phenylhydrazine. (cdc.gov)
  • Therefore, the revised IDLH for phenylhydrazine is 15 ppm based on acute oral toxicity data in animals [Ekshtat 1965]. (cdc.gov)
  • Phenylhydrazine is used to prepare indoles by the Fischer indole synthesis, which are intermediates in the synthesis of various dyes and pharmaceuticals. (wikipedia.org)
  • Lipid peroxidation, hemolysis and thiol contents were studied in intact goat erythrocytes exposed to phenylhydrazine. (scirp.org)
  • An increase in lipid peroxidation, hemolysis and thiol content was observed after phenylhydrazine treatment of erythrocyte. (scirp.org)
  • Phenylhydrazine is the chemical compound with the formula C6H5NHNH2. (wikipedia.org)
  • Phenylhydrazine forms monoclinic prisms that melt to an oil around room temperature which may turn yellow to dark red upon exposure to air. (wikipedia.org)
  • Exposure to phenylhydrazine may cause contact dermatitis, hemolytic anemia, and liver damage. (wikipedia.org)
  • Exposure to phenylhydrazine may cause contact dermatitis, hemolytic anemia, and liver damage. (wikipedia.org)
  • Our results showed that hemolytic anemia induced by phenylhydrazine in rats caused alteration in the blood picture, iron indices, serum biochemical parameters, antioxidant biomarkers, and histopathological picture. (researchgate.net)
  • The aim of the present study is to evaluate the anti-anemic activity of hydro-alcoholic leaf extract of Aegle marmelos against phenylhydrazine induced hemolytic anemia in rats. (journalcra.com)
  • Mice lacking p15Ink4b have lower numbers of primitive RBC progenitors and died shortly after induction of hemolytic anemia by phenylhydrazine injection. (nih.gov)
  • The present study was done to evaluate the anti-anemic effect of beetroot supplement on anemia induced by phenylhydrazine in albino rats. (researchgate.net)
  • In the second group, anemia was induced in rats by intraperitoneal injection of phenylhydrazine at 60 mg/kg in 3 divided doses daily, for 3 consecutive days. (researchgate.net)
  • However, in the phenylhydrazine treated rats, it took longer for the haematocrit to return to normal although initially it was not as low as the bled rats. (lml.com.ly)
  • Phenylhydrazine (60mg/kg) was administered intraperitoneally for 2 days to induce anemia in rats. (journalcra.com)
  • The last three groups received phenylhydrazine as the anemic group. (researchgate.net)
  • Drugs or chemicals which have produced significant hemolysis in G6PD or methemoglobin reductase deficient patients include Dapsone, sulfanilamide, nitrite, aniline, phenylhydrazine, napthalene, niridazole, nitro-furantoin and 8-amino-antimalarials such as primaquine. (nih.gov)
  • This skin notation profile presents (1) a brief summary of epidemiological and toxicological data associated with skin contact with phenylhydrazine and (2) the rationale behind the hazard-specific skin notation (SK) assignment for phenylhydrazine. (cdc.gov)
  • Condensation of o-phenylene diamine with chloro acetic acid gave 2-chloromethyl benzimdazole, which undergoes halide replacement with phenylhydrazines to give the corresponding NN' disubstituted hydrazines. (ijpsr.com)
  • Phenylhydrazine is used to form phenylhydrazones of natural mixtures of simple sugars in order to render the differing sugars easily separable from each other. (wikipedia.org)
  • Phenylhydrazine reacts with carbonyl compounds in neutral or slightly acidic medium to give phenylhydrazones. (expertsmind.com)
  • Thus, the corresponding 2-amino-3-furancarboxaldehyde phenylhydrazones and semicarbazones were obtained upon treatment with phenylhydrazine and semicarbazide, respectively, whereas condensation with malononitrile yielded 2-substituted 6-aminofuro[2,3- b ]pyridine-5-carbonitriles. (enamine.net)
  • Explain Principle Osazone Test or Phenylhydrazine Reaction? (expertsmind.com)
  • Accordingly, the reaction of 1 , phenylhydrazine ( 2a ) and 2-iodobenzaldehyde Fig. 1 Design of novel PDE4 inhibitors ( C ) derived from A . † Electronic supplementary information (ESI) available: NMR spectra of all new compounds. (dokumen.tips)
  • Phenylhydrazine forms monoclinic prisms that melt to an oil around room temperature which may turn yellow to dark red upon exposure to air. (wikipedia.org)
  • The summarized information and health hazard assessment are limited to an evaluation of the potential health effects of dermal exposure to phenylhydrazine. (cdc.gov)
  • Information was considered from studies of humans, animals, or appropriate modeling systems that are relevant to assessing the effects of dermal exposure to phenylhydrazine. (cdc.gov)
  • Studies will utilize flow-cytometric analysis in addition to other hemodynamic and biochemical parameters in mice where anemia is induced using phenylhydrazine or bone marrow transplantation. (nih.gov)
  • A literature search was conducted through April 2014 to identify information on phenylhydrazine, including but not limited to data relating to its toxicokinetics, acute toxicity, repeated-dose systemic toxicity, carcinogenicity, biological system/function-specific effects (including reproductive and developmental effects and immunotoxicity), irritation, and sensitization. (cdc.gov)
  • After haemorrhage, the dual effects of erythropoietin and calcium combine rapidly to re-establish red blood cell numbers but in the case of phenylhydrazine administration, there was no attendant calcium increase and presumably bone marrow is the only recipient of erythropoietin stimulation hence, recovery is less rapid. (lml.com.ly)