Phases derivatives chromatography gel. Medical search. Frequent questions

The main purpose of our study was to detect native zopiclone, its decomposition products and 2-amino-5-chloropyridine in blood and urine by means thin-layer chromatography and gas chromatography (FID and ECD). (medline.ru)
Aliquots of blood, urine samples and zopiclone hydrolysis products were first analyzed by thin-layer chromatography in solvent system benzene-1,4-dioxane-conc. (medline.ru)
The purity of the compounds was monitored by thin layer chromatography (TLC) and the structures of the products were confirmed by elemental and spectral analysis. (ijpsonline.com)
Bhole, R. P. 2013-05-04 00:00:00 Abstract:This paper presents the development and validation of a method for the simultaneous analysis of Cetirizine hydrochloride (CTZ) and Phenylephrine hydrochloride (PHE) using high performance thin-layer chromatography (HPTLC) with densitometric detection. (sagepub.com)

1985) and in rat urine by high-performance liquid chromatography (HPLC) with ultraviolet (UV) absorbance detection following formation of the 2,4-dinitrophenylhydrazone derivative (Shara et al. (cdc.gov)
The enantiodiscriminating capability of each one of these phases was evaluated by HPLC with four families of chiral aromatic compounds composed of alcohols, amines, phenylalanine and tryptophan amino acid derivatives and beta-lactams. (ua.pt)

Moreover, high-performance liquid chromatography studies showed that the dltX mutant was devoid of D -alanine, and electrophoretic mobility measurements indicated that the cells carried a higher negative surface charge. (frontiersin.org)

leaves using vacuum liquid chromatography and normal phase silica-gel column chromatography. (edu.ph)
After portioning between solvent phases, the extract in chromatographed on a silica gel column and then on a thin-layer chromatoplate. (inchem.org)

These groups provide the solid phase with the property of reversible covalent binding of thiol compounds via disulphide-bond formation. (fq.edu.uy)
In order to obviate to said drawback, compounds more stable than hyperforin, such as the salts disclosed in WO 99/41220 and the hydroxy-functionalized derivatives (WO 99/64388) cited above, have recently been prepared. (justia.com)
Compounds are separated on an adsorbent paper (stationary phase) by their varied degree of solubility/mobility in the eluting solvent (mobile phase). (lookformedical.com)
These transformations tolerated a broad range of the nucleophilic reagents thus allowing the synthesis of a wide variety of hetero- and carbocyclic compounds including the derivatives of pyridine, pyrimidine, pyrazole, pyran, dioxane, and isoxazole as well as their heterofused derivatives. (researchgate.net)
The use of a borate buffer solution with pH 9.3 as a mobile phase increases the UV absorption intensity of these compounds and thus lowers the detection limit. (cognacguide.de)
Examples f said compounds are the 14ß-hydroxy baccatin III derivatives disclosed in US 5,705, 508, WO 97/43291, WO 96/36622. (allindianpatents.com)

IE solvent-resistant chiral column, the amylose-tris (3,5-dichlorophenylcarbamate) covalently bonded to the surface of the silica gel. (thelabstore.co.uk)
Unrestricted use of solvents, a wide range of dissolution conditions, the use of any miscible solvent as a mobile phase, dissolved samples, chiral column regeneration. (thelabstore.co.uk)
The role of mobile phase polarity, a mixture of n-hexane and propan-2-ol in different ratios, was also evaluated through molecular dynamics simulations in explicit solvent. (ua.pt)
After the reaction is finished, the solvent is straight vaporized from the reaction blend under lowered pressure, and the resulting deposit is separated and cleansed by silica gel (n-hexane/ethyl acetate) column chromatography to acquire the target item particle. (zspharmac.com)

The terpenoid chiral selectors dehydroabietic acid, 12,14-dinitrodehydroabietic acid and friedelin have been covalently linked to silica gel yielding three chiral stationary phases CSP 1, CSP 2 and CSP 3, respectively. (ua.pt)

For example, some of the hydrazine derivatives described in this section have been used to detect periodate-oxidized glycoproteins in gels. (thermofisher.com)

100 references, on organotin(IV) complexes of the carboxylic acid derivatives are presented with special reference to their methods of synthesis, spectroscopic and structural studies and their biological activities. (degruyter.com)
The synthesis of the ribo - trihydroxy sugar derivative starting from diacetone-D-glucose led to the formation of an inseparable 1:1 mixture of the required compound and its C-3 epimer, i.e., 4- C- hydroxymethyl-1,2- O -isopropylidene-α-D-xylofuranose [10] . (beilstein-journals.org)
Isatin (1-H-indole-2,3- dione) and its derivatives possess diverse biological and pharmacological activities and are widely used as a starting material for the synthesis of a broad range of heterocyclic compound substrates for drug synthesis [ 1 ]. (ijpsonline.com)
In organic synthesis, the dual bonds and incurable amino teams in the oleylamine framework are highly responsive practical groups that can go through a series of chemical improvements, such as acylation of amines, oxidation of double bonds, and so on, and can be utilized to prepare matching Different derivatives of lengthy alkyl chains. (zspharmac.com)
In this study, we explored the catalyst‐free one‐pot multi‐component synthesis of 1,4‐dihydropyridine derivatives by following green chemistry protocol. (researchgate.net)
7 In this article, we present our results on the synthesis, crystal structure and anti-ischaemic activity of new cinnamide derivative of (E)-1-{4-[bis(4-methoxyphenyl)methyl]piperazin-1- yl}-3-(4-chlorophenyl)prop-2- en-1-one (5). (scielo.org.za)
The present relates to a novel intermediates useful in the synthesis of 14ß-hydroxy-1,14-carbonate-deacetylbaccatin III derivatives, and to a process for the preparation thereof. (allindianpatents.com)

The bioassay-guided isolation of ethyl acetate fraction allowed to isolated 6 paeoniflorin derivatives and 2 catechins such as 4-O-methyl-moudanpioside C (1), 4-O-methylbenzoyloxypaeoniflorin (2), oxypaeoniflorin (3), (+)-catechin (4), catechuic acid (5), paeoniflorin (6), benzoylpaeoniflorin (7), albiflorin (8). (ijpsonline.com)
Separation of valerenic acid and its derivatives was performed by TLC using a ternary mobile phase of hexane-ethyl acetate-glacial acetic acid (65:35:0.5 v/v) on silica gel HF 254+366 plates. (scialert.net)
The mobile phase is comprised of Toluene: Ethyl acetate: Methanol: Ammonia (5:2:3:0.4 v/v/v/v). Detection wavelength was 254 nm. (sagepub.com)

Separation was performed on silica gel G 60F254 plates. (sagepub.com)

In the last two decades, the essential oil and valerenic acid derivatives have become more important, not only from a pharmacological point of view, but also for the quality control and standardization of valerian phytomedicines (Hendriks et al . (scialert.net)
Extensive research is at present being carried out for taxan derivatives having higher pharmacological activity and improved pharmacokinetic profile. (allindianpatents.com)

Oleylamine can additionally get lots of useful derivatives with chemical reactions, such as carboxylic acids, alcohols, amides, etc. (zspharmac.com)

The CSP 3 phase, containing a selector with a large friedelane backbone is particularly suitable for resolving free alcohols and their derivatives bearing fluorine substituents, while CSP 2 with a dehydroabietic architecture is the only phase that efficiently discriminates 1, 1'-binaphthol atropisomers. (ua.pt)

molecular sieve chromatography. (termwiki.com)
In order to understand the structural factors that govern the chiral molecular recognition ability of these phases, molecular dynamics simulations were carried out in the gas phase with binary diastereomeric complexes formed by the selectors of CSP 1 and CSP 2 and several amino acid derivatives. (ua.pt)

The principal constituents are bicyclic terpenes (e.g. α-pinene, β-pinene, δ-3-carene), with smaller proportions of monoterpenes, sesquiterpenes and their hydrogenated and oxygenated terpenoid derivatives. (europa.eu)

the moving phase is a liquid. (termwiki.com)
Those ligands are suitable for complexation/enrichment, separations (chromatography, liquid-liquid extraction etc. (naturality.fr)
Quick mixing enhances the contact between the gas stage and the liquid phase. (zspharmac.com)
Liquid chromatography (2. (forextrading-madeeasy.com)

These include the essential oil and its sesquiterpenoids (valerenic acid derivatives), epoxy iridoid esters (valepotriates) and their decomposition products such as baldrinal and homobaldrinal, amino acids (arginine, GABA, glutamine, tyrosine) and alkaloids (Upton et al . (scialert.net)

The invention relates to 1-piperazine- and 1-homopiperazine-carboxylate derivatives, and to the preparation and therapeutic application thereof. (allindianpatents.com)
The present invention relates to hyperforin and adhyperforin derivatives and the use thereof in the pharmaceutical and/or nutritional field, in particular in the treatment of depression and Alzheimer's disease. (justia.com)

carbonation of the vicinal hydroxyls at the 1- and 14-position with phosgene in mehtylene chloride/toluene mixture in the presence of pyridine to give the 1, 14-carbonate derivative: reduction of the carbonyl at the 13-position with sodium borohydride in methanol: removal of the protective groups at the 7- and 10-position to give 14ß-hydroxy-l,14-carbonate-deacetylbaccatin III. (allindianpatents.com)

A particular approach relates to the baccatin II derivatives variously modified with respect to the basic structure. (allindianpatents.com)

With agarose, degrees of thiolsulphinate substitution ranging from 100 to 500 μmol/g of dried derivative can be easily prepared from the same thiol-agarose batch by varying the concentration of the reagent used in the second oxidation step. (fq.edu.uy)
For the derivatives 1 and 2 suitable for single-molecule junctions, the corresponding oxophenalenoxyl radicals 1R and 2R were obtained by oxidation and analysed by electron paramagnetic resonance spectroscopy. (thieme-connect.com)

As nonsulfated gastrin derivatives were shown to be more suitable for tumor targeting by virtue of their CCK-2 receptor selectivity, high affinity, and favorable in vivo profile ( 20 ), Behr et al. (snmjournals.org)

Although no literature citations were found, it would seem that formate in urine and blood could be determined by a method based on ion chromatography (IC). (cdc.gov)

For column storage , remove the acidic or basic additives by flushing the column with the same mobile phase without the additive. (thelabstore.co.uk)
The isolated products were purified via column chromatography and the results acquired from the TLC technique revealed the isolation of two coumarins. (jmchemsci.com)
The solvents used to extract the powdered seeds, follow up the spots on chromatograms and elute the column chromatography were acquired from authenticated international suppliers. (jmchemsci.com)

When the ammonia input quantity is 200kg, identify whether there is water in the released gas phase. (zspharmac.com)

The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations. (gc.ca)

Medicinal modification and new drug delivery methods have led to the development of new derivatives and formulations of scutellarin with improved bioavailability, efficacy, and safety. (cdc.gov)

As a modifier, you can use all solvents that can be used for chromatographic columns such as methanol, ethanol, 2-propanol, acetonitrile, THF, halogen solvents and other silica gel-based chromatography columns. (thelabstore.co.uk)

Dinosterol (4α,23,24-trimethyl-5α-cholest-22E-en-3β-ol) is a 4α-methyl sterol that is produced by several genera of dinoflagellates and is rarely found in other classes of protists. (wikipedia.org)
9~ yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester (tenofovir disoproxil fumarate, Viread®) and (2R, 5S, cis)-4-amino-5- fluoro-l-(2~ hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (emtricitabine, EmtrivaTM, (-)-cis FTC) and their physiologically functional derivatives. (gc.ca)
By observing the importance of the above said problem, the isatin-based Schiff base and spiro isatin derivatives of spirothiozolidin- 4-ones and 5'-methyl-spiro-4-thiazolidiones from 5-substituted isatin and 2-benzoyl-4-chloroaniline were synthesized following the steps given in Figures 1 and 2 . (ijpsonline.com)
The title compound (E)-1-{4-[bis(4-methoxyphenyl)methyl]piperazin-1-yl}-3-(4-chloro- phenyl)prop-2-en-1-one (C 28 H 29 ClN 2 O 3 , Mr = 476.98) (5) was synthesized and studied by the single crystal X-ray diffraction method. (scielo.org.za)
The reaction of cinnamic acid chloride with 1-[bis(4-methoxyphenyl)methyl]piperazine in the presence of triethylamine in dichloromethane at room temperature afforded the corresponding new cinnamide derivative with a total yield of 73.5 % ( Scheme 1 ), which was expected to be a potent neuroprotective agent. (scielo.org.za)
E)-1-{4-[bis(4-methoxyphenyl)methyl]piperazin-1-yl}-3-(4-chlorophenyl)prop-2-en-1-one (5). (scielo.org.za)
13 The title compound (E)-1-{4-[bis(4-methoxyphenyl)methyl]piperazin-1-yl}-3-(4-chlorophenyl)prop-2-en-1-one 5 was obtained as follows:thionylchloride (2mL) and piperadine (1 drop) were added to a stirred solution of (E)-3-(4-chlorophenyl)acrylic acid (4,4 mmol) in dichloromethane (15 mL) at room temperature. (scielo.org.za)

All three phases resolve well the racemates of N-trifluoracetyl and N-3,5-dinitrobenzoyl phenylalanine amino acid ester derivatives. (ua.pt)
Good enantioseparation of beta-lactams and N-benzoyl tryptophan amino acid derivatives was achieved on CSP 1. (ua.pt)

It has now been found that hyperforin and adhyperforin derivatives obtainable by reduction of all double bonds of the isoprene chains and/or by reduction of the keto groups at the 1- and 10-positions to hydroxy groups not only have high stability, but also possess antidepressant, anxiolytic and anti-neurodegenerative activities surprisingly higher than hyperforin and adhyperforin. (justia.com)

A series of 3-[(2 E )-3-substituted-prop-2-enoyl]-2 H -chro men-2-one derivatives (II a-h) were prepared by Claisen-Schmidt condensation of 3-acetyl coumarin with aromatic aldehydes. (ijpsr.com)
These introduced aldehydes and ketones can then be modified with fluorescent or biotinylated hydrazine, hydroxylamine or amine derivatives to label the polysaccharide or glycoprotein. (thermofisher.com)
Alkenes from unsaturated fatty acids and ceramides can also be converted to glycols by osmium tetroxide and then oxidized by periodate to aldehydes, and periodate will oxidize certain β-aminoethanol derivatives such as the hydroxylysine residues in collagen, as well as methionine (to its sulfoxide) and certain thiols (usually to disulfides). (thermofisher.com)

Chromatography on non-ionic gels without regard to the mechanism of solute discrimination. (lookformedical.com)

The experimental conditions for the introduction of thiolsulphinate groups on to agarose have been optimized, as this is one of the most widely used supports in chromatography. (fq.edu.uy)
Phosphorodiamidate morpholino oligonucleotides are widely used to interrogate gene function in whole organisms, and light-activatable derivatives can reveal spatial and temporal differences in gene activity. (cdc.gov)

Quantification of Valerenic Acid and its Derivatives in Some Species of Valeriana L. and Centranthus longiflorus Stev. (scialert.net)
The present study aims to characterize some Iranian wild species of Valerianaceae with respect to their contents of valerenic acid and its derivatives. (scialert.net)
Total valerenic acid derivatives content in different organs of these Iranian wild species ranged from 0.06-1.11% (D.W.). Present results showed that Iranian wild species of Valeriana and Centranthus DC. (scialert.net)

Organic phases were combined and after centrifugation extract was evaporated and residue was redissolved in 20? (medline.ru)

Development and Validatin of a Normal Phase HPTLC Method for Simultaneous Estimation of. (sagepub.com)

This is the first report for the identification and quantification of valerenic acid derivatives in all organs of Valeriana sisymbriifolia , Valeriana alliariifolia and Centranthus longiflorus in comparison with those of commercial Valeriana officinalis . (scialert.net)

Their utility stimulated the development of new synthetic routes for the preparation of coumarin derivatives. (ijpsr.com)

Development and Validation of Retention Models in Supercritical Fluid Chromatography for Impregnation Process Design. (tuhh.de)

Peptide conjugates were obtained in 10%-30% overall yields by solid-phase techniques. (snmjournals.org)

1st incubation: 50 µL of sample is incubated with a testosterone- specific biotinylated antibody and a testosterone derivative labeled with a ruthenium complex. (cdc.gov)
We have developed a series of NPs based on (bio)degradable and biocompatible poly(malic acid) derivatives, poly(benzyl malate) (PMLABe), with its PEG-grafted stealth analog and target-specific biotin-PEG- b -PMLABe one. (frontiersin.org)

Depending on the conditions and type of solid phase used, degrees of substitution ranging from 60 to 500 μmol of thiolsulphinate groups per g of dried support were obtained. (fq.edu.uy)

Formaldehyde has been measured in blood by gas chromatography (GC) in conjunction with mass spectrometry (MS) after derivatization of the formaldehyde to the pentafluorophenylhydrazone (Heck et al. (cdc.gov)

Additionally, for a more accurate determination of total valerenic acid derivatives (including valerenic acid, hydroxyvalerenic acid and acetoxyvalerenic acid) extinction coefficient of each compound in ethanol was used. (scialert.net)

However, only recently we discovered that the photophysical properties of 1 (quantum yields, photostationary states) are superior to those of parent azobenzene, and most of its derivatives [6-8] . (beilstein-journals.org)

This data file contains results of the testing of 1637 males age 12 or more years who participated in the morning examination of phase 1 of NHANES III and for whom serum was still available in the repository. (cdc.gov)

Silica gel plates 60 F 254 (Merck) were used. (medline.ru)

Anatomy14

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Analytical, Diagnostic and Therapeutic Techniques and Equipment73

Phenomena and Processes53

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Thin-layer chromato4

HPLC2

High-performance li1

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Compounds6

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Synthesis7

Ethyl acetate3

Separation1

Pharmacological2

Carboxylic acids1

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Terpenoid1

Liquid4

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Pyridine1

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Urine1

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Acetonitrile1

Methyl7

Amino2

Reduction1

Aldehydes3

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