Phase response. Medical search. Frequent questions

Laboratory studies show elevation of acute phase reactants and abnormal activation of the type I interferon response. (nih.gov)
It is one of a group of proteins, called acute phase reactants that go up in response to inflammation. (medlineplus.gov)
The levels of acute phase reactants increase in response to certain inflammatory proteins called cytokines. (medlineplus.gov)

Whereas the follicular phase of the menstrual cycle can vary in length, the secretory phase lasts approximately 14 days, correlating with the life span of the corpus luteum. (medscape.com)
Fifteen premenopausal women were investigated in the follicular phase of the menstrual cycle with two TRH tests within an interval of 48 to 96 h. (lu.se)

Biotech company Inovio released positive interim data from its Phase I clinical trial of INO-4800, its experimental vaccine against COVID-19. (biospace.com)
In the interim data in 40 healthy volunteers, 94% of the recipients demonstrated an overall immune response at Week 6 after two doses of the vaccine. (biospace.com)
When Moderna released information about the interim Phase I data from its own COVID-19 vaccine, the company did provide at least some data about the number of patients that produced binding antibodies and neutralizing antibodies. (biospace.com)
Inovio expects to begin a Phase II/III clinical trial of the vaccine this summer, pending approval from the U.S. Food and Drug Administration (FDA). (biospace.com)
As a result of an unparalleled global mobilization of science, a search for solutions and a commitment to solidarity, the third phase of the response saw vaccine production and roll out just one year after the pandemic was declared. (who.int)
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial. (msdmanuals.com)

We set out below our response to the detail design proposals following their recent publication and including matters discussed with you at the virtual meeting on 15 September 2020. (brighton-society.org.uk)

LONDON (AP) - Britain's inquiry into the response to the coronavirus pandemic and its impact on the nation entered its second phase Tuesday, with political decision-making around major developments, such as the timing of lockdowns, taking center stage. (valleycentral.com)

Here we describe the cellular pathways involved in the host response to experimental pneumococcal meningitis in specified disease states and brain regions. (biomedcentral.com)

We are very encouraged by the positive interim safety and preliminary cellular and humoral immune response results to date as well as the inclusion of INO-4800 in Operation Warp Speed. (biospace.com)
Host Response to Tumors The immune response to foreign antigens consists of Humoral mechanisms (eg, antibodies) Cellular mechanisms (See also Tumor Antigens. (msdmanuals.com)
Most humoral responses cannot prevent tumor growth. (msdmanuals.com)

Major secondary endpoints including the proportion of patients in clinical response, endoscopic healing, as well as improvement in health-related quality of life, were also significantly higher at week 8 among patients receiving STELARA compared with patients receiving placebo. (jnj.com)
We aimed to quantify the proportion of patients who experience durable responses on ICIs and to compare it with other drug classes. (curie.fr)
Limited evidence from retrospective studies and the phase II ESTIT study (NCT02402998) suggests that earlier use of TPO-RAs after ITP diagnosis may allow a larger proportion of patients to achieve sustained responses after tapering off drug (Červinek et al. (confex.com)

A total of twenty genes functioning in different aspects of plant defense that were monitored over a time course during the changing infection phases showed a coordinated response. (nature.com)
Most importantly this defense response was more prompt in the resistant than the susceptible host indicating that a resistant host makes different choices from a susceptible host during infection which ultimately influences the severity of the disease. (nature.com)
CMS' guidance also attaches a sample plan, Recommended Nursing Home Phased Reopening for States , which complements the federal Opening Up America Again phased reopening plan, [ 1 ] but incorporates stricter criteria in light of the heightened risk of infection to LTCF residents and staff. (nixonpeabody.com)
The major events in the regulation of the host response on a transcriptional level occur within the first 3 days after infection. (biomedcentral.com)
Whereas in the acute phase of the disease immunoregulatory processes prevail in the hippocampus and the cortex, we observed a strong activation of neurogenic processes in the hippocampal dentate gyrus, both by gene expression and immunohistology starting as early as 3 days after infection. (biomedcentral.com)
These include fragmented data systems, easing of public health social measures, insufficient data sharing with WHO and between countries, COVID-19 fatigue, inadequate infection prevention and control policies, the spread of rumours and misinformation, and a politization of the pandemic response," he added. (who.int)

Yet there is an absolute lack of any transcriptional study regarding molecular defense response of sesame against any biotic/abiotic stress. (nature.com)
Understanding plant community responses to combinations of biotic and abiotic factors in different phases of the plant growth cycle. (bournemouth.ac.uk)
Understanding plant community responses to combinations of biotic and abiotic factors is critical for predicting ecosystem response to environmental change. (bournemouth.ac.uk)
We quantified abundance, species richness, evenness, flowering and dominance in relation to biotic and abiotic factors during the growth-, peak-, and recession-phases of the plant growth cycle. (bournemouth.ac.uk)
We show that the relative importance of biotic and abiotic factors varied between plant community properties and between different phases of the plant growth cycle. (bournemouth.ac.uk)

Effective incident response communications require prior planning. (infotech.com)
Assemble a Security Incident Response Communications Team. (infotech.com)
What is an incident response plan for cyber security? (goliathsec.com)
Learn how to manage a data breach with the 6 phases in the incident response plan. (goliathsec.com)
An incident response plan is a documented, written plan with 6 distinct phases that helps IT professionals and staff recognize and deal with a cybersecurity incident like a data breach or cyber attack. (goliathsec.com)
Properly creating and managing an incident response plan involves regular updates and training. (goliathsec.com)
Is an incident response plan a PCI DSS requirement? (goliathsec.com)
Yes, Requirement 12 of the PCI DSS specifies the steps businesses must take relating to their incident response plan. (goliathsec.com)
An incident response plan should be set up to address a suspected data breach in a series of phases. (goliathsec.com)
This phase will be the work horse of your incident response planning, and in the end, the most crucial phase to protect your business. (goliathsec.com)
Have your security policies and incident response plan been approved by appropriate management? (goliathsec.com)
Does the Incident Response Team know their roles and the required notifications to make? (goliathsec.com)
Have all Incident Response Team members participated in mock drills? (goliathsec.com)

In response to the strong need for MHPSS interventions in all phases of emergencies, including preparedness, prevention, response and recovery, IASC reference Group on MHPSS developed the Inter-Agency Standing Committee (IASC) Guidelines for MHPSS in Emergency Settings in 2007. (who.int)
The Emergency Relief Coordinator formally activated an Inter-Agency Standing Committee (IASC) Level 3 emergency response the following day (12 November), noting that the magnitude of this sudden-onset humanitarian crisis justified system-wide resource mobilization. (who.int)

Increased risk and prevalence of mental health problems related to emergencies has led to development of further guidance and support on MHPSS during preparedness and prevention phase. (who.int)
Lessons learnt assessment and communications and response to public health emergencies. (who.int)
core capacities for the detection and assessment of, and · strengthening its leadership and response to, those risks and emergencies, most of which are its collaboration with global attributable to communicable diseases. (who.int)
3 The Philippines' Surveillance in Post Extreme Emergencies and Disasters (SPEED), the mobile-based early warning system, was implemented during the response phase and should be shifted to the Philippine Integrated Disease Surveillance and Response system in the recovery phase. (who.int)

The International Health Regulations (2005), which came control through the improvement, into effect in 2007, impose a binding legal obligation on the development and evaluation of Director-General to strengthen the Organization's alert and new tools, interventions and response capacity in the face of epidemics and public health strategies. (who.int)

PHILADELPHIA, PENNSYLVANIA, October 9, 2018 - The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data showing treatment with a single intravenous (IV) dose of STELARA ® (ustekinumab) induces clinical remission and response in adults with moderate to severe ulcerative colitis (UC) who previously experienced an inadequate response or were intolerant to conventional or biologic therapies. (jnj.com)
About 50 percent of study participants are considered biologic refractory, and 17 percent have a history of inadequate response or intolerance to an anti-TNF and/or Entyvio* (vedolizumab). (jnj.com)

The first phase, which concluded in July, looked at the country's preparedness for the pandemic. (valleycentral.com)
1 The recovery process is defined as "a sequence of interdependent and often concurrent activities that progressively advance a community toward a successful recovery" and extends from ongoing preparedness to long-term recovery with an overlap between the acute response and short-term and intermediate recovery. (who.int)

A pathological complete response, observed in 32% of patients in the study, is recorded only when the esophagus is surgically removed after therapy and no tumor can be found microscopically. (medicaldesignandoutsourcing.com)
Predicting tumor response to PD-1 blockade. (msdmanuals.com)

While the pathophysiologic profile of SARS-CoV-2 is not completely understood, research and clinical studies suggest that both T-cell and antibody immune responses will be important for protection in both mild and serious infections," said Kate Broderick, senior vice president of R&D at Inovio. (biospace.com)
A phase Ib study of pre-operative, locoregional IRX-2 cytokine immunotherapy to prime immune responses in patients with early stage breast cancer. (bepress.com)

State and local health departments should include mental health management in each phase of a disaster (pre-event, response, recovery, and evaluation). (cdc.gov)
Disaster risk management approachs has Increasingly shifted from response focused actions to preventative and proactive actions to reduce risk before hazadous events occur. (who.int)

The primary endpoint is the number (%) of patients with sustained responses off treatment by Month 12. (confex.com)
The primary endpoint of the new Phase 2a trial is to establish continued safety and tolerability of ANAVEX 2-73. (anavex.com)

Objectives To assess baricitinib on patient-reported outcomes (PROs) in patients with moderately to severely active rheumatoid arthritis, who had insufficient response or intolerance to ≥1 tumour necrosis factor inhibitors (TNFis) or other biological disease-modifying antirheumatic drugs (bDMARDs). (bmj.com)
Eltrombopag is a thrombopoietin receptor agonist (TPO-RA) currently approved in the United States for the treatment of ITP in patients who have had an insufficient response to CSs, immunoglobulins, or splenectomy. (confex.com)

At week 8, patients (n=961) were evaluated for clinical remission, endoscopic healing, clinical response, change from baseline in the IBDQ score, and mucosal healing (an endpoint that includes both endoscopic healing and histologic healing). (jnj.com)
which demonstrate that 38% (15/40) of the patients receiving OPAXIO in combination with cisplatin and concurrent radiation achieved a pathologic or endoscopic complete response. (medicaldesignandoutsourcing.com)

Incyte INCY today announced new 104-week results from the pivotal Phase 3 TRuE-V clinical trial program evaluating Opzelura ® (ruxolitinib) cream 1.5% in patients 12 years of age and older with nonsegmental vitiligo, a chronic autoimmune disease characterized by depigmentation of skin. (einpresswire.com)

Findings showed that responses varied with the course of the pandemic. (cdc.gov)

Brands, Inc. (NYSE: YUM) today provided an update on the next phase of its response to the COVID-19 pandemic. (businesswire.com)
Many health experts say that before it's safe to call off social distancing, America needs to move to a second phase of response to the COVID-19 pandemic. (npr.org)
In the company's press release announcing the interim Phase I results for INO-4800, Inovio referenced two studies published earlier this year that found between 33% and 40% of individuals who recovered from COVID-19 had low levels of neutralizing antibodies. (biospace.com)
BEDFORD) - Lt. Governor Suzanne Crouch and the Indiana Office of Community and Rural Affairs today announced that an additional 42 rural Hoosier communities will receive more than $10.09 million in federal grant funding through the COVID-19 Response Program. (wbiw.com)
On April 30, Lt. Governor Crouch announced 61 COVID-19 Response Phase 1 recipients , who received more than $10.7 million in funding. (wbiw.com)
To continue addressing the economic impact caused by COVID-19 on rural Hoosier businesses, OCRA launched a second phase of the COVID-19 Response Program. (wbiw.com)
Funding for the COVID-19 Response Phase 2 funding is derived from Indiana's CARES Act allocation. (wbiw.com)
Jha is the new White House COVID-19 response coordinator. (wsiu.org)
As the Biden administration pushes into the next phase of the COVID pandemic, there will be a new face for the government's response. (wsiu.org)
In a statement, President Biden announced Dr. Ashish Jha, dean of Brown University's School of Public Health, will serve as the new White House COVID-19 response coordinator. (wsiu.org)
Jeff Zients has made contributions the country will never fully appreciate," Andy Slavitt, a member of the COVID response team who left last year, wrote on Twitter. (wsiu.org)
Much later, after being caught flatfooted by the omicron variant, the White House COVID response team aggressively moved to purchase and distribute at-home rapid COVID tests. (wsiu.org)
As many states begin a phased reopening of businesses, CMS recommends certain critical steps before relaxing the restrictions that have been imposed on LTCFs to prevent the spread of COVID-19. (nixonpeabody.com)
The meeting, led by WHO Regional Director Dr Ahmed Al-Mandhari, focused on reviewing the COVID-19 situation, response, and achievements at country level, and addressing common challenges to strengthen WHO's support to countries. (who.int)
During the meeting, Dr Al-Mandhari categorized the ongoing response to COVID-19 into 3 phases. (who.int)
Last year was unprecedent as several challenges faced our response to COVID-19," Dr Brennan said. (who.int)

The amplitude response is the ratio of output amplitude to input, usually a function of the frequency. (wikipedia.org)
Experiments with a commercial microcantilever validate the model, but also reveal an increase of frequency noise in the PLL associated with the parametric gain and phase, which, in most cases, restricts the attainable limit of detection. (nature.com)
The noise in open-loop is studied by measuring the random fluctuations of the noise-driven deflection of the microcantilever, and a model for the power spectral density of amplitude, phase and frequency noises is discussed and used to explain the frequency fluctuations in the closed-loop PLL. (nature.com)
The KH 150 has an exceptionally linear frequency response from 39 Hz to 21 kHz (±3 dB). (neumann.com)

The company will also present detailed dose-response analysis of data from the ongoing Phase 2a Alzheimer's trial of ANAVEX 2-73 PART A at the 14th International Symposium on Advances in Alzheimer Therapy (AAT), which will be presented by Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex, at 12:20 p.m. (anavex.com)
While we are waiting for longitudinal effect data of ANAVEX 2-73 over an extended period of time, the positive dose-response in PART A is an encouraging step and also consistent with the fast mode of action of the sigma-1 receptor. (anavex.com)
Multicenter phase II randomized study evaluating dose-response of antiperistaltic effect of L-menthol sprayed onto the gastric mucosa for upper gastrointestinal endoscopy. (bvsalud.org)
In this phase II, multicenter, double-blind, dose -response study, 131 eligible patients were randomly assigned to receive 20 mL of 0.4% L- menthol (n = 32), 0.8% L- menthol (n = 35), 1.6% L- menthol (n = 30), or placebo (n = 34). (bvsalud.org)
L- menthol suppresses peristalsis in a dose -dependent manner, and the dose -response reaches a plateau at 0.8% L- menthol . (bvsalud.org)

Response to: 'Detection of antinuclear antibodies: added-value of solid phase assay? (maastrichtuniversity.nl)

The trial is independent of the Company's planned larger Phase 2/3 double-blinded, placebo-controlled study of ANAVEX 2-73 in Alzheimer's disease. (anavex.com)

A durable response to treatment was defined as a progression-free survival that exceeded three times the median progression-free survival of the whole population. (curie.fr)
Many patients who achieved a high level of facial repigmentation (≥F-VASI90) in TRuE-V1/TRuE-V2 were able to maintain durable response for one year after discontinuing Opzelura treatment. (einpresswire.com)

Genetic basis for clinical response to CTLA-4 blockade in melanoma. (msdmanuals.com)

Leveraging our previous expertise in MERS with INO-4700, where we demonstrated significant antibody and cellular responses, the breadth and profile of the responses observed to date with INO-4800 targeting SARS-CoV-2 provide a promising read towards further development and addressing the existing public health threat. (biospace.com)

The Association of Acute Phase Proteins in Stress and Inflammation-Induced T2D. (nih.gov)

MEMS devices are good candidates to study the dynamic responses of parametric pumping and resonance 4 due to their small dimensions and presence of mechanical/electrical nonlinearities. (nature.com)
In this work we study the dynamical response of a PI-controlled and parametrically pumped resonator in a digital Phase-Locked Loop, to understand its sensing performance and noise limit. (nature.com)
We conducted a longitudinal cohort study to investigate changes in responses among the general Hong Kong, China, population during the pH1N1 pandemic. (cdc.gov)
We study the quasistatic behavior of the lamellar phase of diblock copolymers under uniaxial compression and tension along the normal direction of the layers, in both the weak segregation limit (WSL) and the strong segregation limit (SSL). (caltech.edu)
Methods In this double-blind phase III study, patients were randomised to once-daily placebo or baricitinib 2 or 4 mg for 24 weeks. (bmj.com)
Conclusions Baricitinib improved most PROs through 24 weeks compared with placebo in this study of treatment-refractory patients with previously inadequate responses to bDMARDs, including at least one TNFi. (bmj.com)
Results from the induction phase of the Phase 3 UNIFI study show that treatment with a single IV dose of STELARA induced clinical remission in a significantly greater proportion of UC patients at week 8, compared with placebo, at both doses studied. (jnj.com)
TAPER (NCT03524612) is an ongoing phase II, open-label, prospective, single-arm study assessing sustained response off treatment in adult patients with ITP receiving eltrombopag, who had relapsed or failed to respond to initial CS treatment. (confex.com)
The LTE evaluated TRuE-V1 and TRuE-V2 study participants from Weeks 52 to 104 in two separate cohorts based on patients who achieved a complete or almost complete response by Week 52. (einpresswire.com)
The new 104-week (two-year) extension of the multi-center Phase 2a clinical trial of ANAVEX 2-73 will follow patients with mild-to-moderate Alzheimer's disease who have already completed 52 weeks in PART B of the study. (anavex.com)
We are pleased to have the impressive and potentially important results of the paclitaxel poliglumex phase II esophageal study published in a peer reviewed journal," said Dr. Howard Safran, M.D., director of the Brown University Oncology Group. (medicaldesignandoutsourcing.com)

A contract to develop a modernized and improved version of the NIOSH Mine Emergency Response Interactive Training Simulation (MERITS), making it compatible with modern computer systems. (cdc.gov)

The implementation of each phase will vary, according to a specific organization's skills and capabilities. (iansresearch.com)
The team should also create a written justification for the response, which helps avoid "moving the goal posts"-a common situation where a stakeholder is firmly entrenched in the notion that the issue requires an immediate response and, subsequently, realigns the organization's risk tolerance to the situation to ensure a response occurs. (iansresearch.com)

Amplifiers, filters, and other devices are often categorized by their amplitude and/or phase response. (wikipedia.org)

The guidelines were developed to enable humanitarian actors and communities to plan, establish and coordinate a set of minimum multi-sectoral responses to protect and improve people's mental health and psychosocial well-being in the midst of an emergency. (who.int)

CONCLUSION Durable responses were more frequent in patients treated with ICIs, although they also occurred in patients treated with other drug classes. (curie.fr)

Transition from the asymptomatic biotrophic phase, characterized by intercellular thick primary hyphae, to the destructive necrotrophic phase, characterized by thin filamentous secondary hyphae, is referred to as the biotrophy-necrotrophy switch (BNS). (nature.com)
It is from this perspective, combined with data from existing documents such as plans, reports and policies, that we highlight the need to define a period of transition from response to recovery of the health sector as it may have important implications on the health system functioning as a whole. (who.int)

The significance of dermal exposure to TMA in immunologic sensitization and on subsequent airway responses is not clearly known. (cdc.gov)
An animal model displaying both an early-phase airway response (EAR) and a late-phase airway response (LAR) after sensitization and subsequent inhalation challenge to a low-molecular-weight chemical has not been previously reported. (cdc.gov)
TMA powder applied to the skin can lead to both immunologic sensitization and subsequent dose-dependent biphasic airway responses after TMA aerosol challenge. (cdc.gov)

Given the limited success in reducing brain damage during the acute disease, it appears imperative to expand the scope of strategies from the acute disease phase into the recovery phase with the aim to improve the outcome of brain injury. (biomedcentral.com)
2 In this paper, this period of overlap between response and recovery in the Philippines occurred three to seven months post-Typhoon Haiyan - February 2014 to July 2014. (who.int)
in the recovery phase, active case finding was resumed. (who.int)
During the overlap period between response and recovery activities, the authors were all working in the health sector at the national level supporting coordination and strategic planning with government and partners and at the field level implementing response activities and revisiting the medium- and long-term programming approach to recovery. (who.int)

The studies investigated persons' risk perceptions and knowledge related to the virus, perceived efficacy of preventive measures, and psychological and behavioral responses. (cdc.gov)
In historical studies, pathologic complete response has correlated with prolonged survival. (medicaldesignandoutsourcing.com)
Further Phase III studies are needed to establish the superiority of 0.8% L- menthol over placebo. (bvsalud.org)
Predictive modelling studies helped to inform the national response, with 7 countries in the Region regularly using modelling to inform public health management cooperation. (who.int)

Each phase of the sample plan outlines criteria for implementation of that phase, visitation and service considerations, and surveys to be performed during each phase. (nixonpeabody.com)

Anavex Life Sciences Corp . ("Anavex" or the "Company") (Nasdaq: AVXL) today announced that the Company has received the approval from the Ethics Committee in Australia to extend the ongoing Phase 2a Alzheimer's trial, which had been requested by patients and their caregivers. (anavex.com)
The multi-center Phase 2a clinical trial of ANAVEX 2-73 consists of an open-label extension for an additional 104 weeks, allowing for the gathering of safety data for ANAVEX 2-73 cumulatively over three years. (anavex.com)

Herbivory became more important during the later phases of peak abundance and recession due to an influx of swans from adjacent pasture fields. (bournemouth.ac.uk)

Berlin - A leak of Germany's draft coal phase-out law as put together by the Ministry for Economic Affairs emerged today. (clientearth.org)
Prof. Dr. Hermann Ott, Head of ClientEarth - Anwälte der Erde , said: "The long-awaited draft of Germany's phase-out law is a shambles. (clientearth.org)
The leaked draft of the coal phase-out law contains changes to many other laws, too, among them a provision in construction law that in the future would limit the expansion of wind energy considerably. (clientearth.org)
ClientEarth - Anwälte der Erde and Greenpeace Germany released a draft coal phase-out law earlier this year , foregrounding the need to set climate protection as the key objective of the law, as this will affect how ministries and courts apply it. (clientearth.org)

In a contingency, the event occurs after the response, with or without contiguity (juxtaposition of events in time). (bvsalud.org)

The Appendix to CMS' guidance advises that with respect to the surveys to be performed during each phase of its sample plan, states should consider certain criteria when prioritizing which facilities to survey first once a LTCF moves into a new phase. (nixonpeabody.com)

We aimed to determine whether there were overall linear trends in participants' perceptions, psychological responses, and behavioral responses to the pandemic. (cdc.gov)

Overall, the present results demonstrated that ultrasound-assisted aqueous two-phase system extraction method was successfully used to extract total phenolics and flavonoids in A. melanocarpa pomace. (unboundmedicine.com)
In luteal phase dysfunction (LPD), the inadequate secretory transformation of the endometrium results from deficient progesterone production. (medscape.com)
The FDA approval was based on results from the phase 3 LUCENT-1 induction and LUCENT-2 maintenance trials, published last July in The New England Journal of Medicine . (medscape.com)

One month after Haiyan, the Strategic Response Plan was released by the United Nations Humanitarian Coordination Team detailing the health sector's priorities to provide life-saving measures, immediate access to water, sanitation, hygiene and to re-establish health services to prevent increased morbidity and mortality. (who.int)

In addition to the light energy conversion, the properties of the continuous phase in the photothermal effect-dominated droplet-based microfluidics, such as the viscosity, thermal conductivity, specific heat, thermal expansion coefficient and boiling point, would also significantly influence the fluid flow and heat transfer occurring in droplets but the underlying mechanisms remains unclear. (techscience.com)
The aim of this work is to describe the transcriptomic changes underlying the complex mechanisms of the host response to pneumococcal meningitis in a temporal and spatial context using a well characterized infant rat model. (biomedcentral.com)
The following mechanisms can cause an inadequate endometrial response to hormonal stimulation during the luteal phase. (medscape.com)

The main reason Germany's 'Coal Commission' was formed was to decide how to manage a coal phase-out to cut carbon emissions in order to protect the climate. (clientearth.org)

PATIENTS AND METHODS We retrieved published phase III randomized trials that included at least one ICI arm in the recurrent and/or metastatic setting. (curie.fr)

Identify and train mental health professionals and response staff to provide counseling, triage, outreach, and education during a crisis or emergency. (cdc.gov)

In multivariable analysis, the effects of treatment with anti-PD-1/PD-L1 agents and of first-line treatment were statistically associated with a higher mean proportion of durable responses. (curie.fr)
Sustained response is defined as a complete response (platelet count ≥ 100×10 9 /L) with platelet counts ≥ 70×10 9 /L maintained for 2 months, followed by dose reduction and treatment discontinuation while maintaining platelet counts ≥ 30×10 9 /L, without bleeding or rescue therapy, until Month 12. (confex.com)
Platelet counts are assessed weekly during the first 8 weeks of treatment, and biweekly thereafter, depending on patient response. (confex.com)
time to regain F-VASI75 and F-VASI90 response after relapse (with reinitiation of Opzelura treatment) was also evaluated. (einpresswire.com)
For those continuing Opzelura treatment, approximately 62% of patients who achieved ≥F-VASI90 at Week 52 maintained response for one year with ongoing Opzelura treatment. (einpresswire.com)

Anatomy11

Organisms9

Diseases11

Chemicals and Drugs52

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

Phenomena and Processes23

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science4

Health Care3

Acute phase reactants3

Follicular phase2

Vaccine6

20201

Coronavirus1

Pathways1

Humoral3

Proportion of patients3

Infection6

Biotic5

Incident Response13

IASC2

Emergencies4

Interventions1

Inadequate response2

Preparedness2

Tumor2

Immune2

Disaster2

Primary endpoint2

Insufficient2

Endoscopic2

Pivotal1

Findings1

COVID16

Frequency4

Dose-response5

Detection1

Company's1

Durable response2

Clinical response1

Cellular1

Inflammation1

Study11

Simulation1

Organization's2

Amplitude1

Coordinate1

Patients treated1

Transition2

Subsequent3

Recovery4

Studies4

Implementation1

Trial2

Important1

Draft4

Occurs1

Guidance1

Participants1

Results3

Establish1

Mechanisms3

Decide1

Trials1

Crisis1

Treatment5