• International Journal of Radiation Oncology Biology Physics , 98 (1), 196-205.e2. (elsevierpure.com)
  • The NCI-supported National Surgical Adjuvant Breast and Bowel Project (NSABP), now part of NRG Oncology, led the US phase 3 trial. (cancer.gov)
  • The two methods of radiation therapy produced similar, if not statistically equivalent, results, noted Frank Vicini, M.D., of 21st Century Oncology of Michigan, who presented the findings of the US study in San Antonio. (cancer.gov)
  • Chief investigator of the PARABLE trial Prof. Charlotte Coles , professor of breast cancer clinical oncology at the University of Cambridge, and consultant oncologist at Addenbrooke's Hospital, explained that standard x-ray radiotherapy is effective for the majority of patients with breast cancer in the U.K. (medicalnewstoday.com)
  • Henry Kuerer is a professor of breast surgical oncology at the University of Texas MD Anderson Cancer Center who has conducted various case studies on breast cancer and related issues. (sdgln.com)
  • Lancet Oncology published the phase 2 trial results and the likelihood of breast cancer recurring in patients. (sdgln.com)
  • The theme of the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting is Advancing Equitable Cancer Care Through Innovation . (cancer.net)
  • 1 Department of Radiation Oncology, Loma Linda University Medical Center, Loma Linda, California. (nih.gov)
  • US Oncology Helps Deliver Latest Cancer Therapies Through Local Community Access to Cutting Edge Research. (disabled-world.com)
  • US Oncology Helps Deliver Latest Cancer Therapies Through Local Community Access to Cutting Edge Research - New CML therapy is 42nd treatment to gain FDA approval as a result of clinical trials in part supported by physicians and patients in the US Oncology Research network. (disabled-world.com)
  • US Oncology, Inc., the nation's leading integrated oncology company, announced today that in less than two decades it has played a role in the development of 42 novel cancer therapies approved by the US Food and Drug Administration (FDA). (disabled-world.com)
  • US Oncology Research contributed more patients in the United States to this study than any other group," said Kathryn Kolibaba, MD, lead investigator in the US Oncology Research network for the Tasigna clinical trial and medical oncologist with Northwest Cancer Specialists-Vancouver Cancer Center. (disabled-world.com)
  • Whether it's to treat a common cancer like breast or prostate or a disease more rare like CML, the ability of the US Oncology Research network to reach patients in their local communities can help speed enrollment of clinical trials and ultimately advance development of new treatment options. (disabled-world.com)
  • This is yet another win, not just for advancing cancer research and cutting-edge therapies, but for the patients these drugs benefit," said Steve Jones, MD, medical director of US Oncology Research and physician with Texas Oncology. (disabled-world.com)
  • We are proud of the team effort within the US Oncology Research network that has allowed independent community-based physicians to participate in the development of new treatments for cancer. (disabled-world.com)
  • US Oncology Research and its physician participants understand that research leads to cancer cures, that new therapies extend survival, and that carefully conducted clinical trials are the only way that progress is achieved. (disabled-world.com)
  • With the approval of Tasigna, US Oncology Research has played a role in the development of 42 cancer therapies approved by the FDA in less than two decades. (disabled-world.com)
  • A phase 2 trial was also recently presented at an oncology meeting - NEOTALA - which focused on another PARP inhibitor, Talzenna (talazoparib), for the treatment of patients with germline BRCA1/2 mutation-positive, HER2-negative breast cancer before undergoing breast surgery. (curetoday.com)
  • Gabriel Hortobagyi, M.D., professor in the Department of Breast Medical Oncology at The University of Texas MD Anderson Cancer Center, will receive the Jane Cooke Wright Lectureship from the American Association for Cancer Research and its Minorities in Cancer Research membership group. (mdanderson.org)
  • Hortobagyi, who holds the Nellie B. Connally Chair in Breast Cancer, is the past-chair of the Department of Breast Medical Oncology and has been a member of MD Anderson's faculty since 1976. (mdanderson.org)
  • Women with early-stage breast cancer treated with lumpectomy followed by radiation therapy rated the cosmetic results for whole-breast and partial-breast irradiation to be equivalent, according to a new analysis of results from the phase III NRG Oncology/NSABP B39-RTOG 0413 clinical trial. (ascopost.com)
  • Results from the new analysis were presented at the 2019 American Society for Radiation Oncology (ASTRO) Annual Meeting in Chicago. (ascopost.com)
  • Taking aspirin in your 40s could cut the risk of cancer developing later in life, according to research published in the Lancet Oncology Wednesday 29 April 2009. (canceractive.com)
  • Single dose intra-operative radiotherapy for early stage breast cancer can be a better alternative to conventional whole breast radiotherapy for most patients during primary tumor management ' stated the principal investigator Professor Jayant Vaidya, Professor of Surgery and Oncology and Scientific Director at University College London when presenting the results of the study. (zeiss.com)
  • The TARGIT-A trial has offered many breast cancer patients a treatment that is well tolerated, effective, convenient and highly cost efficient', summarized Professor William Small, Professor of Radio-oncology at Loyola University, Chicago and one of the world's leading radiation oncologists. (zeiss.com)
  • Department of Radiation Oncology, Stanford University School of Medicine, CA 94305. (lemmo.com)
  • Researchers from the International Agency for Research on Cancer (IARC) have released a new study, published in JAMA Oncology , that quantifies for the first time the global partition of stage at diagnosis of breast cancer in women across 81 countries worldwide. (who.int)
  • The annual meeting of the American Society for Radiation Oncology was held from Oct. 1 to 4 in San Diego and attracted approximately 11,000 participants from around the world, including physicians, oncology nurses, radiation therapists, biologists, physicists, and other cancer researchers. (msdmanuals.com)
  • The conference featured educational courses focusing on radiation, surgical, and medical oncology. (msdmanuals.com)
  • In the multi-institutional phase II study TransTasman Radiation Oncology Group FASTRACK II, Shankar Siva, Ph.D., of the Peter MacCallum Cancer Centre and the University of Melbourne in Australia, and colleagues found that high-dose radiation is an effective treatment option for older patients with kidney cancer who are ineligible for surgery. (msdmanuals.com)
  • Living with metastatic breast cancer (MBC) is one of the wildest roller coasters I've ever ridden. (healthline.com)
  • Dr. Beverly Moy discussed how the central nervous system is a particularly challenge in HER2+ metastatic breast cancer. (slideshare.net)
  • Treatment that is given before there is any indication that the cancer has spread to prevent or delay the development of metastatic breast cancer administered after surgery and/or radiation. (ucsfhealth.org)
  • Bisphosphonates can delay the development of skeletal-related events in women with metastatic breast cancer and show promise in preventing bone loss induced by chemotherapy or hormonal therapy. (medscape.com)
  • prior taxane therapy administered for the treatment of metastatic breast cancer with the below exceptions. (outcomes4me.com)
  • The results from this prevali- the field of cancer biomarkers (11-13), and that approach was dation study showed that patients could be classified into high- adopted here to define predictive serum biomarkers associated versus low-risk groups for developing metastatic breast cancer with tumor relapse in breast cancer patients. (lu.se)
  • In the randomized clinical trials, both whole-breast irradiation (WBI) and accelerated partial-breast irradiation (APBI) were associated with low rates of the cancer recurring in the breast where the disease originally developed. (cancer.gov)
  • We updated our previous report of a phase 2 trial using proton beam radiation therapy to deliver partial breast irradiation (PBI) in patients with early stage breast cancer. (nih.gov)
  • Previously reported results from the 0413 trial found that "post-lumpectomy partial-breast irradiation was not statistically equivalent to whole-breast irradiation," the researchers conducting the new analysis noted. (ascopost.com)
  • The cosmetic outcome of partial-breast irradiation compared with whole-breast irradiation could be an important determinant for radiation method selection. (ascopost.com)
  • I think we should all agree that this is not a reason to rule out partial-breast irradiation. (ascopost.com)
  • The investigators concluded that at 36 months, partial-breast irradiation was more convenient and less fatiguing than whole-breast irradiation in patients not receiving chemotherapy. (ascopost.com)
  • At 36 months, there was no difference, according to the patient, with respect to whole-breast or partial-breast irradiation for global cosmetic score," Dr. Wong said. (ascopost.com)
  • In contrast, the site-physician evaluation at 36 months modestly favored whole-breast over partial-breast irradiation. (ascopost.com)
  • Cosmetic outcomes were rated slightly worse among patients who received partial-breast irradiation and chemotherapy, and among patients who received whole-breast irradiation, but not chemotherapy. (ascopost.com)
  • At 36 months, 86% of patients who had whole-breast irradiation and 81% of patients who had partial-breast irradiation expressed total satisfaction with their results. (ascopost.com)
  • Less than 1% of patients who had whole-breast or partial-breast irradiation said they were totally dissatisfied. (ascopost.com)
  • Reviewing the results, Dr. Wong offered these comments: "This was a meticulous evaluation of cosmesis" with "reassuring results in light of the prior data from the RAPID trial, which showed worse outcomes with partial-breast irradiation at 3 and 5 years. (ascopost.com)
  • Can Multigene Testing Provide Additional Risk Stratification for Patients Considered Eligible for Accelerated Partial Breast Irradiation? (cdc.gov)
  • But many women do not receive the recommended radiation therapy for various reasons, including the inconvenience of traveling to a distant treatment center. (cancer.gov)
  • Studies have shown that by treating the area of the breast in the vicinity of the original tumor, APBI can reduce recurrences . (cancer.gov)
  • After the 26.4-month follow-up, the recurrence of the breast tumor was nullified. (sdgln.com)
  • People with a low grade, or slow-growing, type of luminal A breast cancer typically receive breast-conserving surgery (also called lumpectomy) to remove the tumor followed by hormone therapy and radiation therapy to reduce the risk of the recurrence, which is the chance of the cancer coming back. (cancer.net)
  • All participants had a grade 1 or 2 tumor smaller than 2 centimeters (about ¾ of an inch) that had been removed with breast-conserving surgery and no cancer in the lymph nodes. (cancer.net)
  • The notion of controlling tumor growth through a naturally occurring biochemical mechanism in the body that directs cancer cells into normal channels of differentiation is one of the theoretical foundations of antineoplaston therapy. (cancer.gov)
  • Merck and Eisai are studying the KEYTRUDA plus LENVIMA combination through the LEAP (LEnvatinib And Pembrolizumab) clinical program in various tumor types, including but not limited to endometrial carcinoma, hepatocellular carcinoma, RCC, head and neck cancer, gastric cancer and esophageal cancer across multiple clinical trials. (streetinsider.com)
  • Recent studies, recapitulating results from previously published studies, have confirmed the efficacy of dusquetide as a stand-alone and combination anti-tumor therapy, with radiation, chemotherapy and targeted therapy, in the context of the MCF-7 breast cancer cell line. (constantcontact.com)
  • In addition to the reduction of severe oral mucositis, an acceleration in the clearance of tumor response and an increase in overall survival were also observed in the Phase 2 clinical study as an ancillary benefit to treating oral mucositis in patients receiving chemo-radiation for their head and neck cancer. (constantcontact.com)
  • The primary purpose of this study is to determine whether breast cancer tumors respond (as measured by pathologic complete response: the absence of microscopic evidence of invasive tumor cells in the breast) to combined chemotherapy of AC(doxorubicin and cyclophosphamide) followed by paclitaxel plus trastuzumab or lapatinib or both given before surgery to patients with HER2-positive breast cancer. (stanford.edu)
  • Although the "oncologic results did not meet the criteria for equivalence as defined by the trial, it bears noting that the ipsilateral breast tumor recurrence rates were exceedingly low in both arms of the trial," commented Julia Wong, MD , of the Dana-Farber Cancer Center, Boston, who served as discussant for the ASTRO science highlights session on breast cancer. (ascopost.com)
  • Noninvasive prediction of axillary lymph node breast cancer metastasis using morphometric analysis of nodal tumor microvessels in a contrast-free ultrasound approach. (medscape.com)
  • Correction: Changes in the tumor oxygenation but not in the tumor volume and tumor vascularization reflect early response of breast cancer to neoadjuvant chemotherapy. (medscape.com)
  • Additionally, doctors and researchers have noted that biopsy of a cancerous tumor can cause spreading or "seeding" of cancer cells along the path or track made by the biopsy needle. (newmediaexplorer.org)
  • Within the accuracy of the study, the risk of a local tumor recurrence in the breast is similar and non-breast cancer death is reduced. (zeiss.com)
  • Parameters characterizing the initial breast cancer, the patient and tumor at the time of hyperthermia, and thetreatment were studied in univariate and multivariate analysis for correlation with duration of local control within the hyperthermia treatment field. (lemmo.com)
  • The goal of neoadjuvant treatment is to induce a tumor response before surgery and enable breast conservation. (medscape.com)
  • In one study, Kathy Han, M.D., of the Princess Margaret Cancer Center at the University of Toronto, and colleagues found that liquid biopsy tests looking at persistent human papillomavirus (HPV) circulating tumor DNA (ctDNA) following chemoradiotherapy (CRT) can accurately identify inferior progression-free survival in patients with cervical cancer. (msdmanuals.com)
  • Of this group, 82% of patients had invasive breast cancer and 18% had DCIS only. (cancer.gov)
  • In 2022 alone , there were an estimated 287,850 new cases of invasive breast cancer and 51,400 cases of DCIS diagnosed in women across the United States. (wrbl.com)
  • According to the U.S. National Cancer Institute, around 80% of all invasive breast cancers are ER-positive. (wrbl.com)
  • After three years following initiation of treatment with olaparib, 85.9% of patients were alive and free of recurrent, invasive breast cancer and new second cancers, compared with 77.1% of patients who received a placebo. (hpnonline.com)
  • How Does Invasive Breast Cancer Oncotype Dx Recurrence Score on Core Needle Biopsies Influence Neoadjuvant Treatment Decision? (cdc.gov)
  • however, patients with LCIS have about a 5% 5-y risk and a 20-30% lifetime risk of developing invasive breast cancer, which may be ipsilateral or contralateral and may be ductal or lobular in origin. (medscape.com)
  • Patients with invasive breast cancer that is ER+ or progesterone receptor positive (PR+) should be considered for adjuvant endocrine therapy with tamoxifen or aromatase inhibitors (AIs). (medscape.com)
  • SEATTLE, WA / ACCESSWIRE / September 18, 2023 / One in eight women will be diagnosed with breast cancer during their lifetime. (wrbl.com)
  • the primary objective was to escalate dose utilizing a robotic stereotactic radiation system treating the lumpectomy cavity without exceeding the maximum tolerated dose. (elsevierpure.com)
  • This study is the first to show the safety, tolerability, feasibility, and cosmesis results of a 5-fraction dose-escalated S-PBI treatment for early-stage breast cancer in the adjuvant setting. (elsevierpure.com)
  • Dr. Vicini said that although APBI produced "good results for a large population of women and does remain a good option," the study results also suggested that there are "limits to the extent that we can cut back" on the schedule and dose of radiation for certain patients and still achieve good outcomes. (cancer.gov)
  • Most interesthasbeeninstereotacticradiation(Muranoetal) butfocal therapy maynot apply well forbreastCNScarcinomatosis inpatientsoftenpreviouslytreated  Low-dose radiationhasbeenusedtopotentiate systemicchemotherapyinheadandneck cancer (Arnoldetal) Hypothesis: Low-dose radiationpriortointrathecal trastuzumabmayinduce HER2expressionand improve treatmentefficacyinwomenwithHER2+CNScarcinomatosis. (slideshare.net)
  • NCT05868174 ) is a Phase Ib, open label, single-arm, multicentre dose escalation and dose expansion study to evaluate the safety profile, dosing and activity of TLX250 ( 177 Lu-DOTA-girentuximab) in combination with the DNA damage response inhibitor (DDRi) peposertib, which is an inhibitor of DNA-PK. (aap.com.au)
  • This hypothesis was confirmed in preclinical studies, conducted under a strategic research collaboration between Merck and Telix announced in 2019, [1] and provided evidence that the combined effect of Merck's investigational DNA-PK inhibitor peposertib with Telix's targeted radiation candidate has potential to significantly improve efficacy and reduce the required radiation dose for tumour reduction and remission, compared to targeted radiation alone. (aap.com.au)
  • Cosmetic results may be improved over those reported with photon-based techniques due to reduced breast tissue exposure with proton beam, skin-sparing techniques, and the dose fractionation schedule used in this trial. (nih.gov)
  • The current trial, BNIT-BR-003, will evaluate the safety and biological activity of a fixed dose of MVA-BN®-HER2 following adjuvant chemotherapy in patients with HER-2-positive breast cancer. (stanford.edu)
  • A Phase I clinical trial tests the safety of investigational radiation treatment and also tries to define the appropriate dose of the investigational radiation treatment to use for further studies. (survivornet.com)
  • Among the other studies chosen to be highlighted at the scientific session on breast cancer was a phase Ib trial to assess safety and toxicity and establish the maximum tolerated dose of concurrent cisplatin with adjuvant radiotherapy for women with stage II and II triple-negative breast cancer. (ascopost.com)
  • Patients in the control arm will receive adjuvant radiotherapy to the breast or chest wall (with/without regional nodes) to a dose of 40 Gy / 15 fractions / 3 weeks, while those in the experimental arm will receive a dose of 26 Gy / 5 fractions / 1 week (to the same volume). (authorea.com)
  • Use of a simultaneous integrated boost (dose of 8 Gy and 6 Gy respectively) is allowed in patients who have undergone breast conservation. (authorea.com)
  • [ 6 ] A double-blind, placebo-controlled, randomized phase II trial by Restelli et al found that high-dose vitamin D supplements improved aromatase inhibitor-induced musculoskeletal symptoms in women on adjuvant anastrozole for breast cancer. (medscape.com)
  • For older patients who are already taking aspirin for cardiovascular disease the drug may also provide additional protection against some cancers, but it not yet known whether the baby aspirin can achieve this, or if the full standard dose of 300mg/day will be needed. (canceractive.com)
  • and concurrent radiation dose (p-value for model less than 0.000001). (lemmo.com)
  • Randomized controlled studies stratifying for these pretreatment parameters are felt warranted to confirm the value of adjuvanthyperthermia in the elective treatment of areas of high risk for local-regional recurrent breast cancer and in fields following surgical excision of recurrent disease, particularly in patients in whom full dose radiation therapy cannot be safely administered. (lemmo.com)
  • Background and purpose: Adjuvant radiotherapy of internal mammary nodes (IMN) improves survival in high-risk early breast cancer patients but inevitably leads to more dose to heart and lung. (regsj.dk)
  • Performance of a Genomic Classifier (GC) Within a Phase 3 Randomized Trial of Dose Escalated Salvage Radiotherapy (SRT) After Radical Prostatectomy (RP). (cdc.gov)
  • Tamoxifen can be given at a lower dose (5 mg daily) in patients with noninvasive breast cancer as shown by the babytam trial. (medscape.com)
  • The total radiation dose is roughly the same as for normal mammography screening. (lu.se)
  • Previous studies have shown that after a diagnosis of early-stage breast cancer, a lumpectomy followed by WBI decreases the risk of the cancer recurring in the same breast. (cancer.gov)
  • If you (or a loved one) are dealing with a breast cancer diagnosis, or breast cancer treatment or recovery, check this list of related medical terms to better understand what it's all about. (ucsfhealth.org)
  • In 2007, a breast cancer diagnosis yielded Called Back (Alyson Books), a counter-narrative oriented around the conventional phases of breast cancer treatment (from diagnosis through surgery, chemotherapy, radiation, and "cure"), but that seeks for each phase an uncommon language and conceptual center as point of meditation. (gf.org)
  • Learn more about CanAssist Breast -- a novel prognostic test for predicting the risk of breast cancer recurrence ten years after diagnosis. (medscape.com)
  • Several methods are available for early diagnosis which give good results in early cancer stages. (who.int)
  • The 3D technology is more precise and enables more accurate breast cancer diagnosis. (lu.se)
  • There is a risk of over-diagnosis of breast cancer, and it is important to ensure that the new technique does not contribute to this. (lu.se)
  • We describe five PN programs and the range of tasks their navigators provide across the cancer care continuum (education and outreach, screening, diagnosis and staging, treatment, survivorship, and end-of-life). (cdc.gov)
  • In Sweden, there has been a steady prostate-specific antigen (PSA) velocity for the diagnosis of pros- decrease in age-standardized breast cancer mortality in women up tate cancer (15). (lu.se)
  • The 5-year survival rate when breast cancer has metastasized to distant parts of the body is just 27 percent . (healthline.com)
  • Proton beam radiation therapy for PBI produced excellent ipsilateral breast recurrence-free survival with minimal toxicity. (nih.gov)
  • The press information stated that, "The study, which found that the addition of the innovative heat technique more than doubled the proportion of patients whose tumours responded to chemotherapy without increasing toxicity, is also the first to show that any treatment other than surgery followed by radiation can prolong survival of this type of patient. (news-medical.net)
  • In the phase 3 OlympiA trial , patients treated with this PARP inhibitor had a 42% reduction in invasive disease-free survival, other new cancers and all-cause death after a median follow-up of 2.5 years. (curetoday.com)
  • The data demonstrated that adding Keytruda improved progression-free survival (time after treatment when a patient with cancer lives with the disease without worsening). (curetoday.com)
  • Updated data from this study also demonstrated that adding Keytruda to chemotherapy improved overall survival (percentage of patients who are still alive after starting cancer treatment), with an estimated seven-month improvement. (curetoday.com)
  • A randomized double-blind phase 3 trial, OlympiA was designed to test the efficacy of the Poly (ADP-ribose)-polymerase (PARP) inhibitor drug olaparib and showed that it significantly improved invasive and distant disease-free survival when given for 52 weeks following the completion of such standard therapies as chemotherapy, surgery and radiation. (hpnonline.com)
  • Correction: Multimorbidity and overall survival among women with breast cancer: results from the South African Breast Cancer and HIV Outcomes Study. (medscape.com)
  • Increasing evidence indicates that in postmenopausal women with breast cancer, adjuvant bisphosphonate treatment not only improves bone density but also decreases bone metastasis and improves overall survival. (medscape.com)
  • Page 2 dwelling Americans are more likely to under-utilize cancer screening, to be diagnosed with late-stage disease, to fail to complete recommended treatment, and consequently to die from NIH-PA Author Manuscript cancer.2 Disparities in cancer incidence, morbidity, and survival are, in part, due to logistical, structural, and socio-cultural barriers. (cdc.gov)
  • The investigators observed 100 percent local control and 100 percent cancer-specific survival. (msdmanuals.com)
  • Survival from breast cancer has improved during the past dec- markerserumlevelshavebeenusedpreviously,e.g.,incalculating ades in the Western world. (lu.se)
  • The trial aims to include approximately 175 patients from both Canada and the U.S., all of whom have Grade 1 or 2 Estrogen Receptor positive (ER+) / Human Epidermal Growth Factor Receptor 2 negative (HER2-) breast cancer. (wrbl.com)
  • They were in their early stages of triple-negative or HER2- positive breast cancer. (sdgln.com)
  • Luminal A breast cancer is hormone receptor-positive, HER2-negative cancer that has low levels of the protein Ki-67, which can indicate how quickly cancer cells are growing. (cancer.net)
  • Companion diagnostic designation for FoundationOne CDx may improve access to treatment with capivasertib plus fulvestrant among patients with hormone receptor-positive, HER2-negative breast cancer harboring select alterations. (cancernetwork.com)
  • Data have been recently presented on the use of Lynparza (olaparib) following standard-of-care treatments - including surgery, chemotherapy, hormone therapy or radiation therapy, in patients with BRCA1/2-mutant, early HER2-negative breast cancer who are at high risk for disease recurrence. (curetoday.com)
  • Impact of 21-gene expression assay on staging estrogen receptor-positive HER2-negative breast cancer. (louisville.edu)
  • Clinical and biological heterogeneities in triple-negative breast cancer reveals a non-negligible role of HER2-low. (medscape.com)
  • BRCA2) mutation in Human Epidermal Growth Factor Receptor 2 (HER2)-negative metastatic or locally advanced unresectable breast cancer. (outcomes4me.com)
  • This is a Phase 3, randomized, double-blind, multinational, multicenter study to evaluate the efficacy and tolerability of veliparib in combination with C/P compared to placebo in combination with C/P in participants with a BRCA1 or BRCA2 mutation, as documented by the Sponsor core laboratory, with HER2-negative metastatic or locally advanced unresectable breast cancer who received no more than 2 prior lines of cytotoxic therapy for metastatic disease. (outcomes4me.com)
  • breast cancer must be human epidermal growth factor receptor 2 (her2)-negative. (outcomes4me.com)
  • Impact of the 21-Gene Recurrence Score Assay on the Treatment of Estrogen Receptor-Positive, HER2-Negative, Breast Cancer Patients With 1-3 Positive Nodes: A Prospective Clinical Utility Study. (cdc.gov)
  • As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
  • US and Canadian researchers presented results from both trials at the San Antonio Breast Cancer Symposium on December 6. (cancer.gov)
  • NSABP researchers randomly assigned 4,216 patients with breast cancer who had recently received a lumpectomy to treatment with APBI or WBI. (cancer.gov)
  • Researchers plan to compare the use of proton beam therapy and current radiotherapy in the treatment of breast cancer. (medicalnewstoday.com)
  • The researchers in this particular trial want to test the effectiveness of using proton beam therapy to treat breast cancer in people more likely to develop heart problems related to radiation therapy. (medicalnewstoday.com)
  • Researchers from the Institute of Cancer Research ICR in London, The Royal Marsden NHS Foundation Trust, and The University of Cambridge are all working together to make this trial possible. (medicalnewstoday.com)
  • Researchers then plan to look at the radiation amounts the heart receives in treatment to predict future potential heart problems. (medicalnewstoday.com)
  • Researchers at Atossa Therapeutics are working diligently to harness the drug's full potential across all three phases of the paradigm. (wrbl.com)
  • From June 3 to 7 in Chicago, Illinois, and online, cancer researchers and clinicians from around the world will gather to discuss the latest research and how to ensure that all people receive the cancer care they need. (cancer.net)
  • Because people with luminal A breast cancer are known to have a low risk of recurrence, the researchers in this study were evaluating whether some people with this cancer could avoid radiation therapy after surgery without it impacting their risk of recurrence. (cancer.net)
  • We expect our findings will encourage other researchers to test the approach in other locally advanced cancers. (news-medical.net)
  • What is certain, say researchers, is that germline BRCA1 and BRCA2 sequencing is becoming an important biomarker for the selection of systemic therapy in early breast cancer. (hpnonline.com)
  • Women who have a strong family history of breast cancer are over four times more likely to develop the disease than the general population, according to research published in the British Journal of Cancer by researchers at the University of Toronto in Canada. (canceractive.com)
  • A new study by researchers from the International Agency for Research on Cancer (IARC) shows that. (who.int)
  • The researchers found that both tests were equally effective in identifying minimal residual disease among patients with cervical cancer who completed CRT. (msdmanuals.com)
  • The researchers found that patients receiving the short course and those receiving the conventional course of radiation therapy experienced comparable outcomes. (msdmanuals.com)
  • Early on, Avon developed an innovative public/private/nonprofitpartnership with the YWCA of the USA, Centers for Disease Controland Prevention (CDC), National Alliance of Breast Cancer Organizations(NABCO), and National Cancer Institute, with the goal of improvingwomen's access to breast cancer services. (cancernetwork.com)
  • The Phase III study involved 341 patients who were treated at medical centers in Europe and in the United States. (news-medical.net)
  • But, after starting his treatment and a clinical trial at Rocky Mountain Cancer Centers, he soon had a positive outlook for his future. (disabled-world.com)
  • Investigators at other hospitals and academic centers are already using this type of radiation. (survivornet.com)
  • Globally more than 40,000 patients have already been treated, in over 350 breast cancer centers, with the TARGIT method. (zeiss.com)
  • Seventy patients from four centers who were diagnosed with HPV-positive cervical cancer and treated with CRT were enrolled in the study and followed for just over two years. (msdmanuals.com)
  • By delivering larger individual doses of radiation across fewer treatment sessions, APBI has emerged as an alternative approach to WBI. (cancer.gov)
  • In both studies-and in both treatment arms-the outcomes overall were extremely good," said Larissa Korde, M.D., of NCI's Cancer Therapy Evaluation Program . (cancer.gov)
  • Breast cancer affects people worldwide, and treatment typically involves a combination of therapies. (medicalnewstoday.com)
  • Radiation is a common component of breast cancer treatment, but it can increase the risk of heart problems in some people. (medicalnewstoday.com)
  • Cancer treatment has progressed over the years, with people having access to more targeted therapies. (medicalnewstoday.com)
  • Treatment for breast cancer often involves a combination of several approaches to help ensure effectiveness. (medicalnewstoday.com)
  • Radiation is part of treatment for breast cancer that comes with certain risks. (medicalnewstoday.com)
  • Existing research suggests that it may also be safer than traditional radiotherapy in the treatment of breast cancer. (medicalnewstoday.com)
  • We estimate around a 2% or more lifetime risk - typically this is because their breast tissue or lymph nodes that require treatment are located close to their heart or they already have heart problems. (medicalnewstoday.com)
  • The global breast cancer treatment market was worth $31.9 billion in 2022 and is expected to reach a value of $85.5 billion by 2032, growing at a compound annual growth rate of 10.3% over the ten-year period. (wrbl.com)
  • Breast cancer remains a widely recognized type of cancer, but it is important to stress that there is still a lot of work ahead in terms of prevention and treatment. (wrbl.com)
  • A new drug, (Z)-endoxifen, has shown promising potential in the treatment of ER+ breast cancer. (wrbl.com)
  • In addition, it can reduce cancer cell activity before surgery and also the risk of recurrent or new breast cancer post-initial treatment. (wrbl.com)
  • If successful, (Z)-endoxifen could emerge as a unique and promising treatment option in the fight against breast cancer. (wrbl.com)
  • The company has obtained Health Canada's approval to commence the EVANGELINE study, a phase 2 clinical trial that focuses on a promising new treatment for pre-menopausal women with breast cancer. (wrbl.com)
  • But here's some good news- the breast cancer patients were tested with the pre-surgical treatment and have shown positive results! (sdgln.com)
  • The patients with early-stage breast cancer gave a good response to the targeted cancer treatment. (sdgln.com)
  • The new study was conducted by the University of Texas MD Anderson Cancer Center stating that this adjuvant treatment is all you need to escape the surgery and radiation therapy. (sdgln.com)
  • Principal Investigator for the STARSTRUCK study, Professor Nat Lenzo , GenesisCare Group Clinical Director Theranostics said, "The treatment of advanced cancer can be extremely challenging. (aap.com.au)
  • However, if radiation therapy can safely be avoided, that means patients won't have additional side effects and costs of the treatment. (cancer.net)
  • Antineoplastons were first proposed as a possible cancer treatment in 1976. (cancer.gov)
  • Their inclusion should not be viewed as an endorsement of the content of the websites, or of any treatment or product, by the PDQ Integrative, Alternative, and Complementary Therapies Editorial Board or the National Cancer Institute . (cancer.gov)
  • Sara M. Tolaney, MD, MPH, gives an extensive overview on the current breast cancer landscape and available treatment options. (cancernetwork.com)
  • Rakhshanda Rahman, MD, FRCS, FACS, emphasizes the importance of educating patients and physicians on the potential risks and benefits of new approaches and technologies involved in the de-escalation of breast cancer treatment. (cancernetwork.com)
  • Investigators are assessing rhenium obisbemeda as a treatment for breast cancer harboring leptomeningeal metastases as part of the phase 1/2a ReSPECT-LM trial. (cancernetwork.com)
  • Treatment combined with radiation and surgery can completely cure breast cancer at an early stage. (unlike.net)
  • The treatment proved to be adaptable to all breast sizes and lumpectomy cavity configurations. (nih.gov)
  • While these results are not what we hoped for, we are proud of the foundational role that KEYTRUDA has established in the treatment of certain types of lung cancer, and we are committed to continuing to research how we can further improve responses to our medicines for patients with difficult-to-treat forms of the disease. (streetinsider.com)
  • In cancer, the development of blood vessels can feed tumors and allow them to grow, and drugs that block angiogenesis are being tested as cancer treatment. (ucsfhealth.org)
  • A Phase III study, which utilized the BSD-2000 Hyperthermia System, demonstrated that patients with high risk soft-tissue sarcomas were 30% more likely to be alive and cancer free almost three years after starting treatment if targeted heat therapy (hyperthermia) was added to their chemotherapy treatment. (news-medical.net)
  • The press release also stated that the results increase the case for intensifying the exploration of this type of treatment of other types of cancer. (news-medical.net)
  • Almost three years after starting treatment, they were 42% less likely to experience a recurrence of their cancer at the same site or to die than those who were getting chemotherapy alone, surviving an estimated 120 months before local progression of their disease, compared with an estimated 75 months. (news-medical.net)
  • Of particular interest are adjuvant therapy, treatment of metastatic disease, methods for treatment of locally advanced breast cancer and inflammatory breast cancer. (stanford.edu)
  • For the treatment of breast cancer, some patients undergo chemotherapy, radiation therapy, or hormone therapy. (frontiersin.org)
  • The drug, which was recently approved by the FDA, is for the treatment of adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+CML) in chronic phase. (disabled-world.com)
  • We need research to find better therapies for patients battling cancer today and to help us discover new treatments for those diseases where we still don't have adequate treatment. (disabled-world.com)
  • Drugs like PARP inhibitors, immunotherapy and antibody-drug conjugates are making a great impact on the treatment of patients with several subtypes of breast cancer. (curetoday.com)
  • Clinical trials in the breast cancer space have been focused on treatment options with high response rates and fewer side effects, potentially changing the landscape of breast cancer treatment. (curetoday.com)
  • But certainly, we're going to need to expand our testing for BRCA1/2 in early breast cancer to better identify who are the patients who would benefit from this treatment. (curetoday.com)
  • In this research study, a MRI done during treatment will help doctors adapt the radiation to target the most precise spot where the cancer is located. (survivornet.com)
  • Investigational" means that the way the radiation treatment is delivered is being studied. (survivornet.com)
  • The U.S. Food and Drug Administration (FDA) has approved this radiation machine and these drugs as treatment options for gastric and breast cancer. (survivornet.com)
  • Results were released on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer, reported Houston Methodist Research Institute. (hpnonline.com)
  • He is widely recognized for developing combined therapies for previously inoperable breast tumors, improving multidisciplinary treatment for patients with all stages of the disease and conducting clinical trials to develop treatment regimens that have become standard practices for managing breast cancer. (mdanderson.org)
  • and digital photos of the breasts taken at baseline, and 1 and 3 years after radiotherapy, scored by physicians blinded to the treatment, breast treated, chemotherapy use, and time point. (ascopost.com)
  • There may be some subtle differences in radiation technique or volumes or subtleties in treatment delivery. (ascopost.com)
  • If a five-fraction regimen of breast cancer is proven to be non-inferior, this will result in a significant improvement in the access to radiotherapy, as well as reduced costs of treatment. (authorea.com)
  • Effectiveness of palbociclib with aromatase inhibitors for the treatment of advanced breast cancer in an exposure retrospective cohort study: implications for clinical practice. (medscape.com)
  • In addition, some of the agents used for the treatment of breast cancer have adverse effects on bone (chemotherapy and aromatase inhibitors). (medscape.com)
  • For more information, see Breast Cancer , Breast Cancer Staging , Adjuvant Therapy for Breast Cancer , and Breast Cancer Treatment Protocols . (medscape.com)
  • news you can use today and incorporate into your integrative cancer treatment programme. (canceractive.com)
  • This study will compare the effects of different amounts of aerobic exercise on heart and lung (cardiorespiratory) fitness in post-menopausal women who completed treatment for early-stage breast cancer. (mskcc.org)
  • Gene-Guided Treatment Decision-Making in Non-Small Cell Lung Cancer - A Systematic Review. (cdc.gov)
  • Convert to Phase I Radiation Treatment Modality [1506]? (cdc.gov)
  • HPV ctDNA testing can identify, as early as at the end of CRT, cervical cancer patients at high risk of recurrence or future treatment intensification trials," Han said. (msdmanuals.com)
  • Patients who have often gone through months of treatment prior to radiation, can safely undergo three instead of five weeks of postmastectomy radiation and have similar outcomes," Wong said. (msdmanuals.com)
  • Telix's companion investigational diagnostic imaging agent TLX250-CDx ( 89 Zr-DFO-girentuximab) was the subject of a successful global Phase III trial (ZIRCON trial, NCT03849118 ), which completed enrolment and reported positive top-line data during 2022. (aap.com.au)
  • Visit the Cancer.Net Blog each day of the meeting for more scientific highlights from the 2022 ASCO Annual Meeting and how the new research will affect patient care. (cancer.net)
  • histologically or cytologically confirmed breast cancer that is either locally advanced or metastatic. (outcomes4me.com)
  • such effects include fatigue and rare life-threatening side effects of cardiac disease and second cancers. (cancer.net)
  • PURPOSE: Randomized phase III trial to determine the effectiveness of adjuvant chemotherapy in treating women who have undergone resection for local and/or regional relapsed breast cancer. (stanford.edu)
  • Early in his career, Hortobagyi conducted a landmark study that gave chemotherapy before surgery to breast cancer patients with locally advanced tumors that had not spread to other parts of the body. (mdanderson.org)
  • locally advanced breast cancer must not be amenable to surgical resection or radiation with curative intent. (outcomes4me.com)
  • regimens received in the adjuvant/neoadjuvant setting or for locally advanced breast cancer within the past 6 months will also be considered toward the maximum of 2 prior lines of therapy. (outcomes4me.com)
  • Patients with breast cancer harboring BRCA1/2 mutations appear to be more likely to undergo mastectomies than those without, according to Zachary Kiss, DO. (cancernetwork.com)
  • At the 12th Annual Joining FORCEs Against Hereditary Cancer Conference, Dr. Melinda Telli, an associate professor of medicine at Stanford University School of Medicine in California and director of the breast cancer program at Stanford Cancer Institute, discussed recent data on treatments for cancer subtypes including early-stage BRCA1/2 breast cancer, triple-negative breast cancer and advanced breast cancer. (curetoday.com)
  • That is around the type of complete response rate that we typically see with combination chemotherapy for triple-negative breast cancer with a BRCA1/2 mutation, so I think this is really provocative data," Telli said. (curetoday.com)
  • The paper, "Adjuvant Olaparib for Patients with BRCA1 or BRCA2 Mutated Breast Cancer," is published in the New England Journal of Medicine . (hpnonline.com)
  • suspected deleterious or deleterious breast cancer gene 1 (brca1) and/or breast cancer gene 2 (brca2) germline mutation. (outcomes4me.com)
  • Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells. (louisville.edu)
  • Inflammation is a known precursor of a number of cancers like prostate, breast, colon and so on. (canceractive.com)
  • PURPOSE: To assess the effects of group therapy focused on the experience of living with prostate cancer (PC) on depression and mental well-being among men with the disease and to explore participant experiences of a guided opportunity to 'speak the unspeakable' as it pertains to living with PC. (bvsalud.org)
  • RNA-seq profile of African American men with a clinically localized prostate cancer. (cdc.gov)
  • NCCN Risk Reclassification in Black men with low and intermediate risk Prostate Cancer after genomic testing. (cdc.gov)
  • The Early Breast Cancer Trialists' Collaborative Group found that in postmenopausal women with early breast cancer, adjuvant bisphosphonate therapy produced highly significant reductions in recurrence (rate ratio [RR] 0.86, P =0.002), distant recurrence (RR 0.82, P =0.0003), bone recurrence (RR 0.72, P =0.0002), and breast cancer mortality (RR 0.82, P =0.002). (medscape.com)
  • Breast cancer is one of the world's leading causes of mortality in women 35 years of age or more [1]. (who.int)
  • Analysis of Sociodemographic, Clinical, and Genomic Factors Associated With Breast Cancer Mortality in the Linked Surveillance, Epidemiology, and End Results and Medicare Database. (cdc.gov)
  • Mongolia's Sustainable Development Vision - 2030 states in its objective 3 of part 2.2.2, to reduce the people's unhealthy habits, improve the living environment, strictly enforce quality standards for food products, and decrease mortality per 10 000 population caused by cardiovascular diseases and cancer to 17.4 and 10.5 respectively. (who.int)
  • Rebecca M. Shulman, MD, and Zachary Kiss, DO, discuss findings from a study evaluating differences in outcomes with radiotherapy and disease characteristics of patients with breast cancer harboring BRCA mutations compared with those without mutated disease. (cancernetwork.com)
  • Is social support associated with improved clinical outcomes in geriatric lung cancer patients? (dovepress.com)
  • As part of the FABREC study, Julia Wong, M.D., of the Dana-Farber Brigham Cancer Center in Boston, and colleagues found that patients with breast cancer who undergo implant-based reconstruction immediately following mastectomy and receive a shorter course of radiation therapy experience similar outcomes to patients who receive a conventional course of radiation. (msdmanuals.com)
  • In addition, toxicity and cancer outcomes were similar. (msdmanuals.com)
  • Clin Cancer Res (2017) 23 (3): 666-676. (aacrjournals.org)
  • A recent analysis of patients with newly diagnosed breast cancer in Georgia and California from 2013 to 2017 demonstrated that about a quarter of patients received genetic testing. (curetoday.com)
  • SCR-6852, an oral and highly brain-penetrating estrogen receptor degrader (SERD), effectively shrinks tumors both in intracranial and subcutaneous ER + breast cancer models. (medscape.com)
  • Breast metastatic tumors in lung can be substituted by lung-derived malignant cells transformed by alternative splicing H19 lncRNA. (medscape.com)
  • A Phase I/II study was undertaken to investigate the efficacy and side effects of combined hyperthermia and radiation therapy in the management of presumed or known microscopic residual tumors. (lemmo.com)
  • What also makes (Z)-endoxifen unique is its ability to potentially work in all three areas of the Breast Cancer Paradigm: the prevention window, neoadjuvant phase and adjuvant phase. (wrbl.com)
  • adjuvant/neoadjuvant chemotherapy for one cancer event will count as one prior line of therapy, if received within the past 6 months. (outcomes4me.com)
  • 1 prior line of platinum therapy for breast cancer in any setting (adjuvant, neoadjuvant, or metastatic). (outcomes4me.com)
  • Thermoradiotherapy for residual microscopic cancer: elective or post-excisional hyperthermia and radiationtherapy in the management of local-regional recurrent breast cancer. (lemmo.com)
  • Between February 1985 and March 1991, 262 fields in 89 patients with local-regional recurrent breast cancer were treated with externally administered hyperthermia and radiation therapy. (lemmo.com)
  • Patients felt cosmetic results improved within the first year after surgery and stereotactic body radiation therapy. (elsevierpure.com)
  • I made it through chemo, surgery, and radiation alive. (healthline.com)
  • New results from two clinical trials suggest that either of two types of radiation therapy after breast-conserving surgery for women with early-stage breast cancer can reduce the risk of the cancer returning. (cancer.gov)
  • The standard treatments for breast cancer include surgery, radiation and/or chemotherapy. (wrbl.com)
  • Pre-surgical Therapy May Allow Patients With Breast Cancer To Avoid Surgery! (sdgln.com)
  • These early results show that it can eliminate the chances of surgery and radiation therapy. (sdgln.com)
  • The therapy involved cancer-targeted therapies that were specific and before chemotherapy to surgery. (sdgln.com)
  • Earlier people used to get surgery first and later follow up such therapies, now with the advanced drugs and medications, you can come through the surgical phase and directly go for therapies. (sdgln.com)
  • People aged 55 or older with low-grade luminal A breast cancer who have received breast-conserving surgery. (cancer.net)
  • The phase 3 LUMINA clinical trial found that radiation therapy may not be needed for patients aged 55 or older who have received breast-conserving surgery for low-grade luminal A breast cancer, as identified through biomarker testing. (cancer.net)
  • Participants in the study then received hormone therapy for 5 years after surgery but did not receive radiation therapy. (cancer.net)
  • People aged 55 or older with low-grade luminal A breast cancer, as identified through biomarker testing, may be able to safely avoid radiation therapy after breast-conserving surgery without impacting their risk of recurrence. (cancer.net)
  • Anti-cancer drugs used in combination with surgery and/or radiation to destroy residual cancer cells to prevent or delay recurrence. (ucsfhealth.org)
  • It is not yet known whether chemotherapy is effective in treating women who have undergone surgery and radiation therapy for relapsed breast cancer. (stanford.edu)
  • These results represent the first time a drug that blocks cancer cells from repairing their DNA (called a PARP inhibitor) has been shown to significantly reduce the risk of breast cancer returning in high-risk patients following completion of standard chemotherapy, surgery and radiation therapy. (hpnonline.com)
  • and increased need for radiation, surgery, or pain medication. (medscape.com)
  • XRI research is focused on new preclinical imaging modalities to improve image contrast through dark-field and phase-contrast imaging using synchrotron radiation (in collaboration with MAX IV) and an in-house micro-focus x-ray tube. (lu.se)
  • A phase III randomized, single-blinded trial was conducted in 2009 comparing Calendula to the drug trolamine for prevention of acute dermatitis caused by radiation treatments for breast cancer. (totalhealthmagazine.com)
  • The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services. (mdanderson.org)
  • A better understanding of the potential risks of developing second primary malignancies among survivors of breast cancer could lead to better prevention and management strategies for these patients. (medscape.com)
  • But regular use of the anti-inflammatory drug specifically for cancer prevention is not currently recommended as it has been linked to a number of side-effects including, gastrointestinal bleeding and stomach ulcers. (canceractive.com)
  • use community-based participatory research (CBPR) methods5 to develop and test approaches to increase use of cancer prevention and control interventions by underserved groups and communities who bear an unequal burden of cancer. (cdc.gov)
  • Go to the official source of cancer prevention information: www.cdc.gov/cancer. (cdc.gov)
  • Finally, bone is the most common site of metastasis in breast cancer. (medscape.com)
  • Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
  • This predict the likelihood of a later recurrence, i.e., an indicator that unique longitudinal sample material was collected from each pa- allows risk assessment for breast cancer metastasis, would be tient between 0 and 36 mo after the primary operation. (lu.se)
  • This study reflects two decades of interdisciplinary clinical research by leading radiation oncologists, surgeons, physicists and health economists. (zeiss.com)
  • METHODS Between November 2009 and December 2015, we recruited patients age 18 to 75 years with newly diagnosed, early-stage favorable HL for this international randomized phase III trial. (uni-koeln.de)
  • A new trial seeks to assess whether proton beam therapy for breast cancer reduces heart risks. (medicalnewstoday.com)
  • A​ clinical trial has just launched in the United Kingdom that plans to test the effectiveness of proton beam therapy to treat breast cancer in people at higher risk for heart problems after radiotherapy . (medicalnewstoday.com)
  • The trial is a phase III, multicenter, randomized trial. (medicalnewstoday.com)
  • This is an idea for a novel clinical trial using radiation to make trastuzumab more effective based upon that discussion. (slideshare.net)
  • Dusquetide previously demonstrated benefits in reducing the duration of severe oral mucositis (SOM) in a Phase 2 clinical trial and reduction in SOM rates in the per protocol population in a Phase 3 stud y. (constantcontact.com)
  • Please contact the UVM Cancer Center Clinical Trials Office to learn if a particular trial is enrolling new participants. (uvm.edu)
  • This is a Phase I/II clinical trial. (survivornet.com)
  • Lead author and the OlympiA trial steering committee chair Andrew Tutt, M.D., Ph.D., of The Institute of Cancer Research and King's College London was principal investigator on the portion of study conducted in patients outside the U.S. and will present the results at ASCO. (hpnonline.com)
  • HYPOfractionated Radiation Therapy comparing a standard radiotherapy schedule (over three weeks) with a novel one week schedule in Adjuvant breast cancer: An open-label randomised controlled study (HYPORT- Adjuvant): study protocol for a multicenter, randomized phase III trial. (authorea.com)
  • Along with the results of the FAST Forward trial, the safety of this intervention in advanced node-positive disease requiring regional nodal radiation will be established. (authorea.com)
  • These estimates are used to guide the choice of selection criteria for the randomised Danish Breast Cancer Group (DBCG) Proton Trial. (regsj.dk)
  • These estimates are used to guide the choice of selection criteria for the randomised Danish Breast Cancer Group (DBCG) Proton Trial.Materials and methods: 179 breast cancer patients already treated with loco-regional IMN radiotherapy from 18 European departments were included. (regsj.dk)
  • FASTRACK II is the first multicenter clinical trial of a nonoperative therapy for patients with primary kidney cancer. (msdmanuals.com)
  • Clinical Breast Cancer 2019 Feb;19(1):e261-e269. (louisville.edu)
  • Correction to: National and subnational burden of female and male breast cancer and risk factors in Iran from 1990 to 2019: results from the Global Burden of Disease study 2019. (medscape.com)
  • Cosmesis was slightly poorer, but it was equivalent to whole-breast irradiation in patients receiving chemotherapy. (ascopost.com)
  • Subjects received postoperative proton beam radiation therapy to the surgical bed. (nih.gov)
  • Two large clinical trials compared whole-breast radiation therapy versus partial-breast radiation therapy in some women with early-stage breast cancer. (cancer.gov)
  • The focus of the research program are clinical trials in breast cancer. (stanford.edu)
  • Clinical trials aim to investigate treatments for women with breast cancer who are newly diagnosed or have had a recurrence of breast cancer. (stanford.edu)
  • The inclusion criteria were articles that addressed only breast cancer in women, were randomized clinical trials, and interventions involving physical training with Consort ≥80. (frontiersin.org)
  • Through participation in clinical trials, physicians can do both, treating cancer patients with the best possible care and moving the field forward. (disabled-world.com)
  • This whole study proved beneficial to women who fear breast cancer. (sdgln.com)
  • The study is being conducted in patients with solid tumours expressing carbonic-anhydrase IX (CAIX), a potential pan-cancer target. (aap.com.au)
  • We are pleased to support the commencement of this study with Telix to help determine if there is a potential future clinical benefit regarding the combination of molecular targeted radiation and DNA-PK inhibitors. (aap.com.au)
  • This study included 500 women aged 55 or older with low-grade luminal A breast cancer. (cancer.net)
  • BSD Medical Corporation (NASDAQ:BSDM) reports that significant and "medical practice changing" clinical study results were the subject of a news briefing at Europe's largest cancer congress, ECCO15 - ESMO34, which is being held September 20 to 24, 2009, in Berlin, Germany. (news-medical.net)
  • Trials include participation in the national breast cancer study groups, ECOG and NSABP, as well as the development of new chemotherapy programs. (stanford.edu)
  • One of the biggest studies assessing this in triple-negative breast cancer is the phase 3 Keynote 355 study , which compared Keytruda (pembrolizumab) plus chemotherapy with placebo and chemotherapy. (curetoday.com)
  • The name of the radiation machine involved in this study is the MRIdian Linear Accelerator. (survivornet.com)
  • In this research study, the investigators are researching if getting an MRI during radiation is a feasible way to delivery radiation. (survivornet.com)
  • This research study is a Feasibility Study, which means it is the first-time investigators at this institution are examining this type of MR-guided radiation. (survivornet.com)
  • Circulating 27-hydroxycholesterol, lipids, and steroid hormones in breast cancer risk: a nested case-control study of the Multiethnic Cohort Study. (medscape.com)
  • A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry. (medscape.com)
  • MRI-based breast cancer radiogenomics using RNA profiling: association with subtypes in a single-center prospective study. (medscape.com)
  • Lifetime changes in body fatness and breast density in postmenopausal women: the FEDRA study. (medscape.com)
  • Head-to-head comparison of perfluorobutane contrast-enhanced US and multiparametric MRI for breast cancer: a prospective, multicenter study. (medscape.com)
  • The TARGIT-A randomized, multi-center phase 3 study involving 2298 patients with a median patient follow-up time of 8.6 years meets the highest scientific standards. (zeiss.com)
  • A longitudinal study of four phases was conducted to identify the effect of an educational film on the Health Belief Model and breast self-examination practice of second-year nursing students in Alexandria University. (who.int)
  • The study, a collaborative international effort, investigates the stage at which more than 2 million women were diagnosed with breast cancer, over the past three decades and across different countries and world regions. (who.int)
  • The objective of this systematic review was to identify the effects of different training methods in women who have survived breast cancer (WSBC). (frontiersin.org)
  • MRK ), known as MSD outside of the United States and Canada, and Eisai today provided updates on two Phase 3 trials, LEAP-006 and LEAP-008, evaluating KEYTRUDA, Merck's anti-PD-1 therapy, plus LENVIMA, the orally available multiple receptor tyrosine kinase inhibitor discovered by Eisai, in patients with certain types of metastatic non-small cell lung cancer. (streetinsider.com)
  • As a leader in lung cancer research, we continue to try to advance science for our patients by building upon the standard we set several years ago with KEYTRUDA," said Dr. Gregory Lubiniecki, Vice President, Global Clinical Development, Merck Research Laboratories. (streetinsider.com)
  • Eighty-one percent of the patients had hormone receptor -positive cancer, and 61% of the patients were postmenopausal. (cancer.gov)
  • Generic name for Arimidex, a hormone therapy for advanced breast cancer. (ucsfhealth.org)
  • Brand name for anastrazole a hormone therapy for advanced breast cancer. (ucsfhealth.org)
  • Correction: Expression of hormone receptors is associated with specific immunological profiles of the breast cancer microenvironment. (medscape.com)
  • More research is needed to develop tools such as biomarkers that could help predict which patients with early-stage breast cancer might benefit most from WBI or APBI, according to Dr. Korde. (cancer.gov)
  • How do these two imaging modalities compare in terms of diagnostic accuracy for breast cancer detection? (medscape.com)
  • Patients with early-stage breast cancer, she continued, "can use this information to decide whether APBI is the right course for them individually. (cancer.gov)
  • A risk prediction tool for individuals with a family history of breast, ovarian, or pancreatic cancer: BRCAPANCPRO. (cdc.gov)
  • Women with dense breast tissue face a higher risk of developing breast cancer and being diagnosed with later-stage disease. (wrbl.com)
  • The drug can reduce the density of breast tissue to mitigate the risk of developing breast cancer. (wrbl.com)
  • However, long-term drug therapy is also being researched to reduce the risk of new or recurrent cancer. (wrbl.com)
  • There the identification of the patients was done who were at low risk of cancer recurrence. (sdgln.com)
  • Applying hyaluronic acid to the skin while receiving radiation therapy might increase the risk of some skin complications. (webmd.com)
  • Benign microscopic breast changes known as atypical hyperplasia may increase a woman's risk of developing breast cancer. (ucsfhealth.org)
  • Among the different risk factors, it is estimated that sedentary behavior, obesity, and physical inactivity in particular account for 20-40% of all cancer cases. (frontiersin.org)
  • These results suggest a strong link between ovulatory menstrual cycles and the risk of developing breast cancer, with progesterone playing an important role. (medscape.com)
  • Certain modifiable factors may affect the risk for developing breast cancer. (medscape.com)
  • Examination of fully automated mammographic density measures using LIBRA and breast cancer risk in a cohort of 21,000 non-Hispanic white women. (medscape.com)
  • Association of air pollution with postmenopausal breast cancer risk in UK Biobank. (medscape.com)
  • Studying the association between longitudinal mammographic density measurements and breast cancer risk: a joint modelling approach. (medscape.com)
  • Correction: A prospective case-cohort analysis of plasma metabolites and breast cancer risk. (medscape.com)
  • Many women with breast cancer are postmenopausal and therefore at increased risk for osteoporosis. (medscape.com)
  • In September 2011, denosumab (Prolia) was approved by the U.S. Food and Drug Administration (FDA) to increase bone mass in women at high risk for fracture who are receiving adjuvant aromatase inhibitor therapy for breast cancer. (medscape.com)
  • The lifetime risk of breast cancer in the general population is one in nine. (canceractive.com)
  • Construction and Verification of a Hypoxia-Stemness-Based Gene Signature for Risk Stratification in Esophageal Cancer. (cdc.gov)
  • Perspectives on the factors affecting decisions around Lynch syndrome genetic testing and results sharing for high-risk colorectal cancer patients. (cdc.gov)
  • Contribution of Family History of Head and Neck Cancer and Associated Risk Factors: Analysis of an Internet Based Risk Assessment Tool. (cdc.gov)
  • The risk of distant recurrence in breast cancer patients is difficult to prognostic indices, such as the Nottingham Prognostic Index (6, 7), assess with current clinical and histopathological parameters, and have proven valuable in identifying patients with poor prognosis. (lu.se)
  • The risk of developing distant strated enough prognostic accuracy in breast cancer (10). (lu.se)
  • Many deaths, especially from bone cancer, have occurred in humans following long-term oral exposure to radium-226 and radium-228. (cdc.gov)
  • The authors assessed two liquid biopsy assays, including a digital polymerase chain reaction test and a sequencing-based assay (HPV-seq) that enables highly sensitive detection and accurate HPV genotyping from baseline plasma cell-free DNA, the main cause of cervical cancer. (msdmanuals.com)
  • Participants had received biomarker testing to confirm that 13.25% or less of their cancer cells had Ki-67. (cancer.net)
  • And, 89.9% of participants had no signs of cancer at 5 years and 97.2% were still alive at the time of follow-up. (cancer.net)
  • The authors randomly assigned 400 patients to a short course (three weeks) or conventional course (five weeks) of radiation after mastectomy with immediate implant-based reconstruction. (msdmanuals.com)