• Professor Graeme Henderson is Professor of Pharmacology and Head of Department, Department of Pharmacology, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK. (opioids.wiki)
  • Angel P Tabancay Jr joined the faculty at USC Mann in July 2015 as a Lecturer in the Department of Pharmacology and Pharmaceutical Sciences. (usc.edu)
  • Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid (UCM), Instituto de Investigación Sanitaria Hospital 12 de Octubre (Imas12), Instituto de Investigación Neuroquímica (IUINQ-UCM), Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Avda. (mdpi.com)
  • Co-evolution of these strains with enhanced virulence, transmissibility and selectivity for specific hosts can be attributed to the introduction of agriculture, civilization and clustered human population in urban areas 6 . (nature.com)
  • By testing multiple isogenic bacterial mutants for virulence factors, we identify the S. aureus serine protease V8 as a critical mediator in evoking spontaneous itch and alloknesis. (iasp-pain.org)
  • CNS Pathology in the neurological mutant rats zitter, tremor and zitter-tremor double mutant (spontaneously epileptic rat, SER). (kyoto-u.ac.jp)
  • Rat neurological disease creeping is caused by a mutation in the reelin gene. (kyoto-u.ac.jp)
  • Creeping: a new mutant rat with neurological disease. (kyoto-u.ac.jp)
  • C3H/HeBir), gene-knockout, and transgenic strains that spontaneously develop colitis. (inotivco.com)
  • Using pharmacology, gene knockout, behavior, and histology in mice, the authors show quite convincingly that Na V 1.1 in sensory neurons is essential for normal motor behavior and contributes to proprioceptor excitability. (elifesciences.org)
  • METABOLIC ACTIVATION SYSTEM: Post-mitochondrial fraction (S9 fraction) from rats treated with Aroclor 1254 was prepared according to Maron and Ames (1983). (europa.eu)
  • Komeda Zucker Creeping rat derived from a closed colony of the Zucker fatty rat by spontaniously mutation at Tokyo Medical College in 1983. (kyoto-u.ac.jp)
  • However, acyclovir or ganciclovir resistant mutants with alterations in the viral DNA polymerase may be resistant to foscarnet and may not respond to therapy with foscarnet. (druglib.com)
  • Although depression has historically been linked to alterations in monoaminergic pharmacology and adult hippocampal neurogenesis, new data increasingly implicate broader forms of dampened plasticity, including plasticity within the cell. (frontiersin.org)
  • Effects of Light-at-Night on the Rat Liver - A Role for the Autonomic Nervous System. (uva.nl)
  • UDS activity in the rat liver of the human carcinogens benzidine and 4-aminobiphenyl, and the rodent carcinogens 3,3'-dichlorobenzidine and direct black 38. (cdc.gov)
  • 1990. Cell replication and unscheduled DNA synthesis (UDS) activity of low molecular weight chlorinated paraffins in the rat liver in vivo. (cdc.gov)
  • The splice variants exhibit differences in their rate of onset and recovery from agonist-induced internalization but their pharmacology does not appear to differ in ligand binding assays. (opioids.wiki)
  • 1986. Excretion of radioactivity from rats and rabbits following cutaneous application of two 14C-labeled azo dyes. (cdc.gov)
  • green fluorescent protein (GFP) fusions revealed egl-2 expression in a subset of neurons and muscles that could explain the mutant behavioral defects. (jneurosci.org)
  • Genetic mapping of the rat mutation creeping and evaluation of its positional candidate gene reelin. (kyoto-u.ac.jp)
  • The complex regulation of Na v s, together with the anatomical rostral shift of the DRG harboring injured fibers in C57BL/6 J mice, emphasize that caution is necessary and preliminary anatomical experiments should be carried out for gene and protein expression studies after SNI in mouse strains. (biomedcentral.com)
  • In F18 progeny, a rat which did not have tm mutation was separated and established as a control strain of WTC (NBRP No.0020). (kyoto-u.ac.jp)
  • Here we report that the behavioral defects in the C. elegans egl-2 mutant are caused by a gain-of-function ( gf ) mutation in an eag-like K + channel. (jneurosci.org)
  • Behavioral and pharmacological studies of these mutants may provide insight into the genetic and mechanistic basis of K + channel dysfunction in vivo . (jneurosci.org)
  • In 1980, a spontaneous tremor mutant rat was found in the colony of Kyo:Wistar (Yamada, 1985). (kyoto-u.ac.jp)
  • Genetic profiling of two phenotypically distinct outbred rats derived from a colony of the Zucker fatty rats maintained at the Tokyo Medical University. (kyoto-u.ac.jp)
  • This observation lead Henri Boulard to the isolation of a tropical strain of yeast named Saccharomyces boulardii ( Sb ) from lychee and mangosteen fruit , which is nowadays the only commercialized probiotic yeast. (vdocuments.net)
  • Stimulation of secretory IgA and secretory component of immunoglobulins in small intestine of rats treated with Saccharomyces boulardii. (ac.ir)
  • Response of human and rat small intestinal mucosa to oral administration of Saccharomyces boulardii. (ac.ir)
  • Hier sind GZMB ELISA Kits für eine Vielzahl von Species wie anti-Human GZMB, anti-Mouse GZMB, anti-Rat GZMB zu finden. (antikoerper-online.de)
  • even Na v 1.3, known to be upregulated in rat neuropathic pain models, was lower in the SNI mouse model. (biomedcentral.com)
  • More recently, models of mouse IBD have been developed using naturally occurring mutant mouse strains (e.g. (inotivco.com)
  • We evaluated interaction between mutant human disrupted-in-schizophrenia 1 (mhDISC1) and maternal immune activation implicated in schizophrenia and mood disorders. (researchgate.net)
  • Superoxide dismutase (SOD) activity of rat blood was determined using SOD activity assay kit (E-BC-K022-M). (elabscience.com)
  • The cerebellum of the mutants shows severe hypoplasia with the reduction of the molecular and granular layers and malposition of Purkinje cells in the white matter. (kyoto-u.ac.jp)
  • It was here on this day, that the world first became aware of the existence of Homo sapiens superior, or mutants, those humans born with extraordinary powers, when the terrorist they only known as "Magneto" attempted to commandeer this base. (uncannyxmen.net)
  • 4 Its existence was further confirmed by radioligand binding studies using rat brain homogenates. (opioids.wiki)
  • Tricyclic antidepressants reverse egl-2(gf) mutant phenotypes, suggesting that EGL-2 is a tricyclic target. (jneurosci.org)
  • However, the challenge of a successful TB treatment remains daunting owing to the emergence of multidrug-resistant (MDR) TB - that is, resistance to at least both isoniazid and rifampicin - and extensively drug-resistant (XDR) TB, in which MDR strains develop resistance to any fluoroquinolone and at least one of the three second-line injectable drugs. (nature.com)
  • 5-7 spike-and-wave complex associated with behavioral absence-like seizure starts at about 14 weeks of age in tm / tm rats and at about 26 weeks of age in tm /+ rats (Serikawa,1987 and Higashiguchi, 1991). (kyoto-u.ac.jp)
  • Preventive effects of different probiotic formulations on travelers' diarrhea model in Wistar rats: preventive effects of probiotics on TD. (ac.ir)
  • Mutant EGL-2( gf ) channels exhibited a negative shift in voltage dependence of activation, and both wild-type (WT) and mutant currents were blocked by imipramine. (jneurosci.org)
  • The δ subunit mRNA was present at wild-type levels in the mutant granule cells, indicating a post-translational loss of the δ subunit. (jneurosci.org)
  • A new model of petit mal epilepsy: spontaneous spike and wave discharges in tremor rats. (kyoto-u.ac.jp)
  • Hcn1 is a tremorgenic genetic component in a rat model of essential tremor. (kyoto-u.ac.jp)
  • A 9L gliosarcoma transplantation model for studying adoptive immunotherapy into the brains of conscious rats. (colorado.edu)
  • Foscarnet does not require activation (phosphorylation) by thymidine kinase or other kinases and therefore is active in vitro against HSV TK deficient mutants and CMV UL97 mutants. (druglib.com)
  • Accumulation of N-acetyl-L-aspartate in the brain of the tremor rat, a mutant exhibiting absence-like seizure and spongiform degeneration in the central nervous system. (kyoto-u.ac.jp)
  • Cannabidiol showed potent activity against a variety of methicillin-resistant Staphylococcus aureus (MRSA) strains of clinical relevance. (lavvan.com)