• CARL pioneered computational mapping of 'chaotic' heart rhythm disturbances (arrhythmias), targeting mechanistic drivers for atrial and ventricular fibrillation (AF, VF) using machine learning and computational models. (stanford.edu)
  • Specific support has been via grants HL70529 and HL162260 for ventricular arrhythmias, and HL103800, HL83359, HL122384, HL149134, and several SBIR grants for atrial arrhythmias. (stanford.edu)
  • Dr. Rayani has experience treating conditions like Arrhythmias, Atrial Fibrillation and Hypertensive Heart with Failure among other conditions at varying frequencies. (sharecare.com)
  • Electrical cardioversion delivers energy synchronized (ie, perfectly timed) to the QRS complex and is used to treat arrhythmias such as AF, atrial flutter (AFL), or ventricular tachycardia (VT) with a pulse. (mhmedical.com)
  • I am a cardiologist specializing in the care of individuals with cardiac arrhythmias (irregular heartbeats) and conduction system abnormalities (a problem with the electrical system that makes your heart beat), with a focus on atrial fibrillation . (mskcc.org)
  • Problems such as atrial arrhythmias are very common and quite benign, with little influence on the patient's hospital course or long‐term prognosis. (thoracickey.com)
  • The specific dysrhythmias for which chemical cardioversion is an option include supraventricular tachycardias (e.g., atrial fibrillation and atrial flutter) and ventricular tachycardia. (mhmedical.com)
  • The most common tachydysrhythmias are AV nodal reentrant tachycardia, AV reentrant tachycardia, atrial fibrillation, and atrial flutter. (mhmedical.com)
  • Typical ECG findings with SVT include narrow-complex tachycardia, electrical alternans, evidence of atrial activation (P', F, or f waves), and response to treatments that slow down AV conduction. (vin.com)
  • The short refractory period leads to more rapid transmission of atrial impulses, which can result in supraventricular tachycardia. (ccasociety.org)
  • Atrial fibrillation (AF) can be very dangerous in the setting of WPW, as conduction of atrial impulses at rates of up to 500 beats per minute can result in ventricular tachycardia or ventricular fibrillation. (ccasociety.org)
  • The symptoms and signs are like any sudden paroxysmal tachycardia, but the ventricular rate is the clue, after carotid pressure, to the diagnosis of atrial flutter with 2:1 block. (medquizzes.net)
  • Atrial flutter is a regular narrow-complex tachycardia characterized by a rapid atrial rate (typically around 300/min), atrioventricular (AV) node conduction block with a ventricular response of approximately 150/minute, and a "sawtooth" pattern on an electrocardiogram (ECG). (lecturio.com)
  • The tachycardia can either be an atrial tachycardia or a ventricular tachycarrhythmia. (wikidoc.org)
  • He was hypoxic and had episodes of supraventricular tachycardia and rapid atrial flutter (ventricular rate 160-200 beats/min). (rcjournal.com)
  • Clinical pharmacology studies have demonstrated the beta-blocking activity of metoprolol, as shown by (1) reduction in heart rate and cardiac output at rest and upon exercise, (2) reduction of systolic blood pressure upon exercise, (3) inhibition of isoproterenol-induced tachycardia, and (4) reduction of reflex orthostatic tachycardia. (pillsync.com)
  • Verapamil hydrochloride does not alter the normal atrial action potential or intraventricular conduction time, but in depressed atrial fibers it decreases amplitude, velocity of depolarization, and conduction velocity. (nih.gov)
  • 2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. (empendium.com)
  • Typical atrial flutter with variable conduction of 3:1 and 4:1 at a ventricular rate of ~75. (teachim.org)
  • Patients with atrial fibrillation and a very low left ventricular ejection fraction can be presumptively diagnosed as having an primary idiopathic dilated cardiomyopathy with secondary atrial fibrillation . (wikidoc.org)
  • Following aggressive rate control (pharmacologic and conversion of rhythm) in 10 patients initially diagnosed as having an idiopathic dilated cardiomyopathy , there was an improvement in left ventricular function at 30 months [7] . (wikidoc.org)
  • Ninety-one patients with sustained atrial fibrillation (75 patients) or flutter (16 patients) were entered into a double-blind, randomized multicenter study of one of two doses of dofetilide (4 or 8 micrograms/kg body weight) or placebo. (qxmd.com)
  • This property accounts for the ability of verapamil hydrochloride to slow the ventricular rate in patients with chronic atrial flutter or atrial fibrillation. (nih.gov)
  • 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. (empendium.com)
  • Lexiscan ® (regadenoson) injection is a pharmacologic stress agent indicated for radionuclide myocardial perfusion imaging (MPI) in patients unable to undergo adequate exercise stress. (lexiscan.com)
  • In clinical trials, hypersensitivity reactions were reported in fewer than 1 percent of patients. (lexiscan.com)
  • The cornerstone of treatment in patients with atrial fibrillation (AF) is to reduce symptoms and improve the quality of life (QoL). (jafib.com)
  • Factors associated with an increased risk of thromboembolic events in patients with atrial fibrillation (AF) include increasing age, rheumatic heart disease, poor left ventricular function, previous myocardial infarction, hypertension and a past history of a thromboembolic event. (aafp.org)
  • A clinical decision making rule (HINTS) can help to more rapidly identify stroke patients to initiate acute therapies faster. (traumayellow.com)
  • We recommend use of the CHA 2 DS 2 VASc as a simple clinical based stroke risk score to initially identify 'low stroke risk' patients that should not be offered antithrombotic therapy to prevent stroke and reduce mortality. (guidelinecentral.com)
  • For patients with AF of greater than 48 hours or unknown duration undergoing elective electrical or pharmacologic cardioversion, we recommend therapeutic anticoagulation with well-managed VKA (INR 2-3) or a NOAC using dabigatran, rivaroxaban, edoxaban or apixaban for at least 3 weeks before cardioversion or a transesophageal echocardiography (TEE)-guided approach with abbreviated anticoagulation before cardioversion rather than no anticoagulation. (guidelinecentral.com)
  • For patients with AF of greater than 48 hours or unknown duration undergoing elective electrical or pharmacologic cardioversion, we recommend therapeutic anticoagulation (with VKA or NOAC) for at least 4 weeks after succesful cardioversion to sinus rhythm rather than no anticoagulation, regardless of the baseline risk of stroke. (guidelinecentral.com)
  • For patients with AF of documented duration of 48 hours or less undergoing elective cardioversion (electrical or pharmacologic), we suggest starting anticoagulation at presentation (low-molecular weight heparin or unfractionated heparin at full venous thromboembolism treatment doses) and proceeding to cardioversion rather than delaying cardioversion for 3 weeks of therapeutic anticoagulation or a TEE-guided approach. (guidelinecentral.com)
  • For patients with AF and hemodynamic instability undergoing urgent cardioversion (electrical or pharmacologic), after successful cardioversion to sinus rhythm, we recommend therapeutic anticoagulation (with VKA or full adherence to NOAC therapy) for at least 4 weeks rather than no anticoagulation, regardless of baseline stroke risk. (guidelinecentral.com)
  • Rapid ventricular response in atrial fibrillation patients is a daily occurrence in the emergency department. (healthybpclub.com)
  • Nowadays, flecainide is recommended as one of the first line therapies for pharmacological conversion as well as maintenance of sinus rhythm in patients with atrial fibrillation and/or supraventricular tachycardias. (wjgnet.com)
  • We herein review the current clinical data related to flecainide use in clinical practice and some concerns about its role in the management of patients with coronary artery disease. (wjgnet.com)
  • The 2014 ACC/AHA/HRS Guideline for the Management of Patients with Atrial Fibrillation offers a comprehensive approach to treating this condition. (pcmedproject.com)
  • Maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with AF/AFl lasting more than 1 wk, and who have been converted to normal sinus rhythm. (mhmedical.com)
  • In more critically ill patients who may require an additional period of ventilatory or pharmacologic support, adherence to these time‐related recommendations may need to be modified, and withdrawal of "intensive care" must be carefully evaluated and not rushed. (thoracickey.com)
  • Intravenous dofetilide can convert sustained atrial fibrillation or flutter to sinus rhythm. (qxmd.com)
  • The typical findings of AP function in sinus rhythm are preexcitation, in which depolarization of the ventricles occurs in part or fully through the accessory pathway that is separate from the AVN and earlier than expected after atrial depolarization. (ccasociety.org)
  • He was volume resuscitated, and pharmacologic anti-arrhythmic therapy was initiated, but he was unable to maintain sinus rhythm. (rcjournal.com)
  • Digitalis toxicity is not a laboratory diagnosis but a clinical diagnosis. (medscape.com)
  • 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. (empendium.com)
  • In this setting, AV nodal blocking drugs such as adenosine, verapamil, digoxin and esmolol are contraindicated as their use will divert atrial impulses to the AP. (ccasociety.org)
  • Identify the key ECG findings for atrial flutter (AF) and use three key features to distinguish it from other supraventricular tachycardias (SVTs). (teachim.org)
  • Atrial fibrillation (AF or Afib) is a supraventricular tachyarrhythmia and the most common kind of arrhythmia. (lecturio.com)
  • Today, atrial fibrillation (AF) is the most frequent arrhythmia encountered in clinical practice and the most commonly cardioverted arrhythmia. (mhmedical.com)
  • Atrial fibrillation, the most common cardiac arrhythmia, increases stroke risk and can exacerbate underlying heart disease. (pcmedproject.com)
  • Of note, these recommendations apply to atrial fibrillation (AF) and atrial flutter, regardless of the pattern of arrhythmia (i.e. paroxysmal, persistent, or permanent). (pcmedproject.com)
  • 2-7 The second is pharmacologic or chemical cardioversion. (mhmedical.com)
  • The decision on which type of cardioversion to use is governed by the patient's clinical condition. (mhmedical.com)
  • Pharmacologic cardioversion, also called chemical cardioversion, uses antiarrhythmic medication instead of an electrical shock to restore the heart's normal rhythm. (mhmedical.com)
  • AV nodal transmission time is heart-rate-dependent and is modulated by autonomic tone and circulating catecholamines to maximize cardiac output at any given atrial rate. (msdmanuals.com)
  • In the setting of a healthy AV node and no pharmacologic AV nodal blockade this the atrial rate is typically conducted at a 2:1 producing a ventricular rate of ~150bpm. (teachim.org)
  • An abrupt and fixed SVT at a rate of 150bpm should always raise suspicion for atrial flutter and can be effectively identified with vagal maneuvers or imitation of AV nodal blockade. (teachim.org)
  • Atrial flutter is due to a large re-entry circuit in the cavo-tricuscpid isthmus (CTI) often producing sawtooth P waves at a rate ~300bpm with a 2:1 conducted ventricular rate of 150bmp (in the absence of AV nodal disease or blockade). (teachim.org)
  • Atrial flutter is managed similarly to atrial fibrillation with rate control and anticoagulation. (teachim.org)
  • 1 Management of AF requires assessment and treatment of the underlying cause, control of the rate, consideration of pharmacologic or electric cardioconversion and consideration of anticoagulation. (aafp.org)
  • Clinical scientific studies recommend that apixaban could possibly produce consistent anticoagulation and a potentially optimal threat:advantage stability. (betaamyloid-signal.com)
  • In 1899, Henschen [ 1 ] reported on his clinical findings after performing percussion and auscultation on the thorax of elite Nordic cross-country skiers. (scienceopen.com)
  • Morphologic findings include atrial enlargement without increased ventricular wall thickness or ventricular cavity dilation, the absence of eosinophilic infiltration, and the absence of pericardial disease. (medscape.com)
  • Management includes avoidance of precipitating factors, simple adaptive maneuvers, volume expansion, and pharmacologic agents. (medquizzes.net)
  • Pathophysiologic correlates of thromboembolism in nonvalvular atrial fibrillation: II. (arizona.edu)
  • A focused update released in 2019 includes new evidence in support of novel drugs and devices to prevent thromboembolism, as well as other clinical considerations. (pcmedproject.com)
  • 240 bpm in cats) and require atrial or atrioventricular junctional tissue for its initiation and maintenance. (vin.com)
  • a Symphony Health Solutions, NonRetailSource, July 2022, based on Astellas market definition of pharmacologic stress agents, as used in single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI). (lexiscan.com)
  • This study sought to determine the safety and efficacy of a single bolus of intravenous dofetilide, a pure class III antiarrhythmic agent, for the termination of sustained atrial fibrillation or flutter. (qxmd.com)
  • However, its efficacy is greater in flutter--a response that contrasts with the poorer response seen with class I agents. (qxmd.com)
  • Flecainide acetate is a class IC antiarrhythmic agent and its clinical efficacy has been confirmed by the results of several clinical trials. (wjgnet.com)
  • The high oral bioavailability, low volume of distribution, reduced plasma clearance and favorable therapeutic index exhibited by apixaban led to its variety for clinical growth as an oral anticoagulant. (betaamyloid-signal.com)
  • It is caused by rapid, uncontrolled atrial contractions and uncoordinated ventricular responses. (lecturio.com)
  • Impulses are transmitted through the atria to the atrioventricular (AV) node via preferentially conducting internodal tracts and unspecialized atrial myocytes. (msdmanuals.com)
  • The clinical manifestations of WPW syndrome reflect the associated tachyarrhythmia episodes-rather than the anomalous ventricular excitation per se. (medscape.com)
  • Direct-current defibrillation was subsequently pioneered and introduced into clinical practice by Bernard Lown in 1962. (mhmedical.com)
  • C. They tend to be recucurrent when an underlying structural cause such as atrial disease or mitral disease is the dominant pathophysiologic factor. (rjmatthewsmd.com)
  • Feeling tired, weak, confused, or dizzy are all symptoms of AFib, but the most common is a quivering or fluttering heartbeat. (healthybpclub.com)
  • Which of the following features determines the patient's clinical course and prognosis? (medquizzes.net)
  • These effects, and preliminary clinical data, suggest that it may be effective in the treatment of atrial fibrillation and flutter. (qxmd.com)
  • The presence of an accessory pathway influences the choice of correct pharmacologic treatment. (ccasociety.org)
  • You may need treatment for paroxysmal atrial fibrillation, or it may happen infrequently enough that your doctor recommends just monitoring your condition. (healthybpclub.com)
  • E. The chronic or long standing PSVT'S like atrial flutter or fibrillation do not revert without treatment,often fail to revert even with attempted treatment and if reverted will often recur despite therapy. (rjmatthewsmd.com)
  • This case demonstrates the result of atrial flutter conducted at variable 3:1 and 4:1 due to the patient taking metoprolol at baseline. (teachim.org)
  • Dr. Faisal Merchant, MD is a Cardiology Specialist in Atlanta, GA. They specialize in Cardiology, has 20 years of experience, and is board certified in Clinical Cardiac Electrophysiology. (healthline.com)
  • A 47-year-old woman develops accelerated hypertension (blood pressure 210/105 mm Hg) but no clinical symptoms except frequent headaches. (medquizzes.net)