• Ephedrine (EP) is a sympathomimetic amine and found in many pharmaceutical preparation, Chinese crude drugs and nutritional supplements. (earticle.net)
  • Ephedrine (EPH) is a sympathomimetic amine similar in structure to the synthetic derivatives amphetamine and methamphetamine . (wikidoc.org)
  • Ephedrine is a sympathomimetic amine - that is, its principal mechanism of action relies on its direct and indirect actions on the adrenergic receptor system, which is part of the sympathetic nervous system or SNS . (wikidoc.org)
  • Ephedrine is commonly used as a stimulant , appetite suppressant, concentration aid, decongestant and to treat hypotension associated with regional anaesthesia. (wikidoc.org)
  • Ephedrine is a central nervous system (CNS) stimulant that is often used to prevent low blood pressure during anesthesia . (cloudfront.net)
  • Pharmaceutical drug preparations of PPA have varied in their stereoisomer composition in different countries, which may explain differences in misuse and side effect profiles. (wikipedia.org)
  • The knowledge gained from reading and comprehending the contents of this course can greatly assist the healthcare professional in identifying, treating, and providing an appropriate referral to patients who misuse methamphetamine. (netce.com)
  • [18] In mice, ephedrine is known to stimulate thermogenesis in the brown adipose tissue , but because adult humans have only small amounts of brown fat, thermogenesis is assumed to take place mostly in the skeletal muscle . (cloudfront.net)
  • Central nervous system or CNS involvement is present, but the predominant clinical effects are caused by involvement with the sympathetic segment of the peripheral nervous system due to the fact that while ephedrine does cross the blood-brain barrier, it doesn't do this very efficiently (efficient crossers with similar modes of action would include amphetamine and methamphetamine). (wikidoc.org)
  • Companies producing for export extract US$13 million worth of ephedrine from 30,000 tons of ephedra annually, 10 times the amount that is used in traditional Chinese medicine. (wikidoc.org)
  • In 2019, the 0 overwhelming majority of ATS seized in the region was 2014 2015 2016 2017 2018 2019* methamphetamine and the seizure amount rapidly has Amphetamine Methamphetamine "Ecstasy" increased annually since 2016. (docslib.org)
  • This licensing requirement applies to all drug establishments except those solely dealing in some natural health products, for which prescriptions are not required and that are for human use in dosage form, including traditional medicines (i.e. traditional herbal medicines as well as traditional medicines such as Chinese, ayurvedic (East Indian) and aboriginal (North American) medicines), homeopathic preparations and vitamin and mineral supplements. (gnhpconsulting.com)
  • Drug products include prescription and non-prescription pharmaceuticals, disinfectants and sanitizers with disinfectant claims. (gnhpconsulting.com)
  • In addition, urban-dwelling gay males are experiencing an alarming increase in methamphetamine abuse, resulting in rapid spread of HIV infection fueled by unsafe sexual practices. (netce.com)
  • the effect of adding ephedrine is to increase the number of vesicles released during each action potential and possibly to extend the time during which noradrenaline has an opportunity to have an effect on the post-synaptic neuron by virtue of the fact that the reuptake complex has to process both noradrenaline AND ephedrine, presumably a longer process. (wikidoc.org)
  • Since then, several trafficking of narcotic drugs, psychotropic substances and their precursors, Drug Situation report 2019 (Almaty, 2020) and countries in the region experienced a significant rise in Drug Situation report 2018 (Almaty, 2019) the seizure of methamphetamine.238,239,240 A noticeable *Data collection for 2019 is preliminary and only from the increase was observed in Azerbaijan which reported CARICC Drug Situation report 2019. (docslib.org)
  • Number of "ecstasy" and methamphetamine seizure cases The rise in seizures of methamphetamine in Central Asia in Georgia , 2014 and 2018 coincided with the increase in the manufacture, traffick- ing and seizures of methamphetamine in neighbouring "Ecstasy" regions, specifically South -West Asia. (docslib.org)
  • [6] Dietary supplements containing ephedrine are illegal in the United States, [6] with the exception of those used in traditional Chinese medicine , where its presence is noted by má huáng . (cloudfront.net)
  • EP is a diastereomer of pseudoephedrine (PSE) and both have been used for the illegal production of methamphetamine (ME). (earticle.net)
  • Precursor chemicals have a wide legitimate use in the production of consumer goods such as pharmaceuticals, fragrances, flavoring agents, petroleum products, fertilizers and paints. (gnhpconsulting.com)
  • The production of ephedrine in China has become a multi-million dollar export industry. (wikidoc.org)
  • Electrodialysis method of preparation Hypophosphorous acid is simple and equipment investment is small, it is suitable for mass production. (syntheticchemicallab.com)
  • Ephedrine is also found to have quick and long-lasting responsiveness in congenital myasthenic syndrome in early childhood and also even in the adults with a novel COLQ mutation. (cloudfront.net)
  • Both AMP and METH were detected, with the predominant detection of S-(+)-METH indicating widespread illegal use of METH, which is primarily produced by a clandestine synthesis procedure that involves the reduction of ephedrine/pseudoephedrine. (bvsalud.org)
  • Ephedrine increases post-synaptic noradrenergic receptor activity by (weakly) directly activating post-synaptic α-receptors and β-receptors, but the bulk of its effect comes from the pre-synaptic neuron being unable to distinguish between real adrenaline or noradrenaline from ephedrine. (wikidoc.org)
  • Like pseudoephedrine it is a bronchodilator , with pseudoephedrine having considerably less effect. (cloudfront.net)
  • Methylxanthines such as caffeine and theophylline have a synergistic effect with ephedrine with respect to weight loss. (cloudfront.net)
  • Some pharmaceutical drugs, when taken together, have also been implicated in the cause of déjà vu. (wikipedia.org)
  • If you are a pharmaceutical manufacturer and you assemble drugs or other using precursors, you will also require a special licence for handling precursors. (gnhpconsulting.com)
  • Over 200 compounds, including pesticides, pharmaceuticals and personal care products, drugs of abuse and their metabolites were identified. (springer.com)
  • A review of pharmaceuticals occurring in water bodies worldwide indicated that non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics and carbamazepine occur widely in Europe, Hong Kong and the USA (Fekadu et al. (springer.com)
  • Quantities of amphetamine-type methamphetamine and "ecstasy" stimulants seized, 2014-2019 120 Although the region's drug market is dominated by canna- bis and opioids, in recent years, synthetic drugs have been 100 237 making their way into Central Asia and Transcaucasia 80 (later referred to as Central Asia). (docslib.org)
  • For instance, almost 1 kg of methamphetamine combating the illicit trafficking of narcotic drugs, psychotropic seized in Tajikistan, in March 2020, originated in substances and their precursors, Express analysis of major drugs seizure Afghanistan.242 facts in CARICC Member States (based on mass media reports), 2018: May, July, August and December, and 2019: January. (docslib.org)
  • Ephedrine is a non- catecholamine sympathomimetic with cardiovascular effects similar to those of epinephrine: increased blood pressure, heart rate and contractility. (cloudfront.net)
  • As an alkaloid, having some small amount of ephedrine within a noradrenaline vesicle reduces the overall pH of the vesicle. (wikidoc.org)
  • Since April 2004, the US FDA has banned the sale of ephedra, Sida cordifolia, and other products that contain ephedrine. (webmd.com)
  • Ephedrine has been linked to serious side effects including high blood pressure , heart attacks , loss of consciousness, and death. (webmd.com)
  • Thus, medical, mental health, and other healthcare professionals working in a variety of settings with a variety of patient populations are likely to encounter patients who have used or are currently using methamphetamine. (netce.com)
  • Urban waters are under increasing environmental threat from emerging pollutants (EPs) originating from inputs of pharmaceuticals and personal care products (PPCPs) as well as household, agricultural and industrial chemicals (Archer et al. (springer.com)
  • Ephedrine promotes modest short-term weight loss , [17] specifically fat loss, but its long-term effects are unknown. (cloudfront.net)