Pharmaceutical antiviral agents. Medical search. Frequent questions

Since its founding in 2008, the EIDD has discovered and advanced two antiviral compounds to licensing events with corporate partners and advanced two antiviral to clinical testing. (grc.org)
One of these compounds (ebselen) also exhibited promising antiviral activity in cell-based assays. (nature.com)
To facilitate the rapid discovery of antiviral compounds with clinical potential, we developed a strategy that combines structure-assisted drug design, virtual drug screening and high-throughput screening to repurpose existing drugs to target SARS-CoV-2 M pro . (nature.com)
The offered pharmaceutical products are processed with utmost care using quality approved chemical compounds, ingredients and advanced technology as per the global quality standards. (doctordanger.com)
The pharmaceutical products provided by us are processed with utmost care from quality assured chemical compounds and the latest machines as per the industry set standards. (doctordanger.com)
In particular, the present invention is directed to a combination therapy comprising administration of certain antiviral compounds and immune modulator compounds. (justia.com)
The hydrophobic pocket in VP1, into which antiviral compounds bind, is in an "open" conformation similar to that observed in drug-bound HRV14. (utmb.edu)
Her team has been studying many aspects of emerging RNA viruses, including identification of unknown viruses using novel biotechnologies, mechanisms of pathogenesis and development of antiviral compounds. (cgu.edu.tw)
Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting ALK2 activity and pharmaceutical compositions comprising such compounds. (justia.com)

It quickly became apparent that the use of combinations of these direct-acting antivirals (DAAs) could limit emergence of resistant variants while also providing rapid and profound viral suppression. (medscape.com)

This report contains information on treatment and chemoprophylaxis of influenza virus infection and provides a summary of the effectiveness and safety of antiviral treatment medications. (cdc.gov)
and 6) consideration of antiviral treatment for outpatients with confirmed or suspected influenza who do not have known risk factors for severe illness, if treatment can be initiated within 48 hours of illness onset. (cdc.gov)
The two antiviral agents with specific activity against influenza A viruses are amantadine hydrochloride and rimantadine hydrochloride. (cdc.gov)
Pharmaceutical drugs for influenza (Relenza and Tamiflu) are now readily available. (drweil.com)
Tamiflu and Relenza work against influenza type A and B. Relenza also has been studied as a preventive agent. (drweil.com)
Among these, Molnupiravir is a broadly acting antiviral therapy active against various coronaviruses including SARS-COV-2, alphaviruses, influenza, RSV, and Ebola. (grc.org)
The incremental cost-effectiveness ratios ranged from $440 USD/QALY (intravenous antiviral agents to treat hospitalized patients with influenza-like (HINI) illness) to $15,000,000 USD/QALY (universal meningococcal serotype B vaccination), with a median of $49,000 USD/QALY, while 37 interventions were "cost-saving" (lower costs and higher QALYs relative to an alternative policy or no intervention) (e.g., one-dose varicella vaccination). (cgdev.org)
This research includes molecular surveillance of Taiwanese strains, mechanistic study of host-restriction of influenza virus infection, pathogenesis study and development of anti-flu agents. (cgu.edu.tw)
The information on this page should be considered as examples of background information for the current influenza season for clinical practice regarding the use of influenza antiviral medications. (cdc.gov)
Actualización sobre el virus la influenza aviar A (H5N1) en los seres humanos. (cdc.gov)
Effectiveness of antiviral treatment in human influenza A(H5N1) infections: analysis of a Global Patient Registry. (cdc.gov)
Impact of Prompt Influenza Antiviral Treatment on Extended Care Needs After Influenza Hospitalization Among Community-Dwelling Older Adults. (cdc.gov)

My expertise focuses on the area of Pharmaceutical and Biomedical Sciences. (researchgate.net)
Notably, I worked as Research Professor in Pharmaceutical Sciences at Ewha Womans University, South Korea. (researchgate.net)

Some antiviral and antineoplastic agents and other pharmaceutical agents : views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Lyon, 12-19 October 1999. (who.int)

Though, efficacy remains disputable for antiviral drugs that are employed for viral disorders. (ijpsr.com)
There are many synthetic antiviral drugs that have a large number of side effects and have narrow therapeutic window range, while in the other hand herbal formulations have minimized side effects. (ijpsr.com)
Because antiviral agents taken prophylactically may prevent illness but not subclinical infection, some persons who take these drugs may still develop immune responses that will protect them when they are exposed to antigenically related viruses in later years. (cdc.gov)
While they can be used for other things, such as for packaging, raw materials can be mixed to create ingredients for prescription drugs, ranging from binding ingredients to active pharmaceutical ingredients. (politifact.com)
Active pharmaceutical ingredients are then the active and primary parts of prescription drugs, allowing the drug to do what it needs to do. (politifact.com)
In addition to this, the inflating utilization of efficacious drugs like corticosteroids, antiviral agents, and antibiotics is also creating a positive outlook for the market. (imarcgroup.com)
Infectious diseases that were commonplace less than a generation ago are now increasingly rare because of vaccines and various antiviral drugs. (chem-tox-ecotox.org)
At the same time it initiated an urgent need by big pharmaceutical companies and research centers of medical institutions worldwide to search for new drugs and vaccines to combat the new virulent coronavirus. (chem-tox-ecotox.org)

In recent years, it has been reported that many herbal plants contain antiviral agents which combat a human disease that is caused by pathogenic viruses. (ijpsr.com)
The natural products which are obtained from plants as antiviral agents against viruses have gone through researches to check the efficacy and potentials of the herbal products in the prevention of viral disorders. (ijpsr.com)
Leveraging the Company's deep understanding of antiviral drug development, nucleos(t)ide chemistry, biology, biochemistry and virology, Atea is developing novel product candidates to treat single stranded ribonucleic acid, or ssRNA, viruses, which are a prevalent cause of serious viral diseases. (globenewswire.com)
Substantial antiviral activity was observed in ca. 20%, which is higher than might be expected given the limited metabolic differences between viruses and their hosts. (umn.edu)
The frequent antiviral activity may represent phytoalexins elaborated to protect against plant viruses. (umn.edu)

The medicinal plants contain phytochemicals that have antiviral properties. (ijpsr.com)
It covers methods of virtual screening and computational validation of identified phytochemicals as potential antiviral agents against the SARS-CoV-2 virus. (benthamscience.com)

This finding gives further insight into pharmaceutical treatments' efficacy in HCMV cases. (lu.se)
The research team found that human NUDT15 enzyme hydrolyzes the active metabolites in the medicine and therefore limit its efficacy for such antiviral treatments. (lu.se)

He has 30 years of experience in medicinal chemistry and drug development within the pharmaceutical industry and has held positions of increasing responsibility in both drug discovery and development. (grc.org)
Since leaving Procter and Gamble in 2001, Dr. Natchus lead the chemistry and development efforts in the area of metabolic disorders at Somatocor Pharmaceuticals and was the Vice President of R&D at Metastatix. (grc.org)
Journal of Organic and Pharmaceutical Chemistry» was begun to publish in 2003 and is regarded as assignee of «Fìzìologìčno aktivnì rečovini» journal that was founded in 1966. (edu.ua)
The Organizing Committee of the MedChem -Russia conference heartily invites academic and university researchers, foreign scientists, representatives of the pharmaceutical business and medicine, undergraduate students and Ph.D. students to attend the 5 th Russian Conference on Medicinal Chemistry, which will be held on October 5-8, 2021 in Volgograd. (medchem21.com)
Six opening lectures by leading specialists will be followed by oral presentations by young scientists, two poster sessions, as well as round tables on educational programs in medicinal and pharmaceutical chemistry fields to discuss ways to accelerate the implementation of innovative developments into practice. (medchem21.com)
Thus, in Volgograd there are all the essentials for combining the efforts of industrial pharmaceutical enterprises, as well as research and educational institutions working in the field of organic synthesis and medicinal chemistry, which will solve the strategic task of providing the population with modern medicines. (medchem21.com)

Offered pharmaceutical products are highly treasured due to their properties like accurate composition, effectiveness, reliable usage, purity and long shelf life. (doctordanger.com)
Of the 143 intervention-specific cost-effectiveness ratios reported in these studies, nearly 70 percent focused on vaccine or pharmaceutical strategies, with the remainder spread across broader approaches, such as screening or testing strategies, school closures, or stockpiling of supplies. (cgdev.org)
In the pharmaceutical industry, the effectiveness of a drug plays a pivotal role in its success. (psmarketresearch.com)
Many research studies have shown that humic acid can help in increasing the effectiveness of antiviral agents. (psmarketresearch.com)

The value of a broad spectrum antiviral addressing multiple viral pathogens in poultry stocks increases the potential utility of the compound for routine commercial application as well as its use in the event of more serious Avian Flu outbreaks. (biospace.com)

Currently, there are no targeted therapeutic agents for the treatment of this disease, and effective treatment options remain very limited. (nature.com)
Hexal Pharmaceuticals shares its presence with fellow foremost top most excellence driven pharmaceutical producers, engaged in manufacturing and marketing several therapeutic molecules under WHO-GMP guidelines. (doctordanger.com)
The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations. (gc.ca)

In 2008, he became a founding, senior member of the management team for the Emory Institute for Drug Development where he has focused his efforts on the Discovery and Development of antivirals for the treatment of pathogenic viral infections. (grc.org)
Also comprised in the present invention is a pharmaceutical composition for use in the treatment and/or prevention of a HBV infection. (justia.com)
Because antiviral treatment is intended for persons with cur- ratory capacities and practices relating to HCV testing, data rent HCV infection, these persons need to be distinguished presented at the CDC 2011 symposium on identification, from persons whose infection has resolved. (cdc.gov)
Today there are new game-changing medicines at hand that offer the promise of an end to chronic hepatitis C. These medicines, called direct acting antiviral agents, are safer to use, cause fewer side-effects and can cure over 95% of cases with a treatment course of 12-24 weeks. (who.int)
This shortened treatment duration allowed for more rapid testing of new agents and combinations, and the field took a rapid step forward between 2011 and 2017. (medscape.com)
The competition for US Food and Drug Administration (FDA) approval of new agents among several pharmaceutical companies also meant that the time-honored process of issuing treatment guidelines every 3-5 years by societies would not be adequate. (medscape.com)

From antibiotics to antivirals, pain relievers to anticancer agents, these quizzes offer insights into the diverse world of pharmaceuticals. (proprofs.com)
This textbook summarizes preliminary knowledge of bioactive molecules which serve as pharmaceuticals, their use, synthesis and mode of action, as well as the production of commercial constituents such as ethanol, citric acid, antibiotics, amino acid, and vitamins. (benthamscience.com)

Antiviral agents include acyclovir, foscarnet, or ganciclovir for varicella-zoster virus (VZV), herpes simplex virus (HSV), and cytomegalovirus (CMV). (medscape.com)
Today, antiviral agents such as Ganciclovir (GCV) and Valganciclovir are the most common clinical treatments for patients with such infections by targeting the viral DNA polymerase. (lu.se)

Previous in vitro studies have demonstrated QR- 441(a) to be a potent antiviral agent against H5N1 (Avian Flu). (biospace.com)

The apex of endocannabinoid research seems to have been reached with the clinical development, and also in some cases, the marketing, of synthetic or natural pharmaceuticals targeting this signalling system, which followed the understanding of the physiological and pathological role of endocannabinoids in several conditions, a role that was investigated first in rodent experimental models and then in humans. (benthamscience.com)

On the basis of randomized controlled studies and in-vivo studies, and in-vitro studies, some agents are utilized all across the globe. (ijpsr.com)
found that the in vitro antiviral activity and selectivity index of the aryloxy phosphoramidate (ProTide) prodrug of the acyclic nucleoside phosphonate tenofovir (tenofovir alafenamide) can be dramatically improved by replacing the aryloxy pro-moiety with an appropriate tyrosine derivative. (nih.gov)
zPREDICTA is developing an in vitro human airway model to screen new and repurposed agents against SARS-CoV-2. (who.int)

Suicide gene systems that convert nontoxic systemically delivered prodrugs to active chemotherapeutic agents have been delivered via adenoviral vectors directly into cancer cells. (medscape.com)

The stockpile now includes 900 types of pharmaceuticals - from generic antivirals to nerve agent antidotes - as well as 134,000 pallets of equipment and 13,570 portable beds. (huffpost.com)

Acic - Pharmacological action Acic is an antiviral agent. (doctordanger.com)

As the Company's resources are invested in pharmaceutical research and development, investment in advertising for the COLD-EEZE brand at comparable levels as competitors is limited. (biospace.com)

Avian Flu Compound - QR-441(a): Positive results were achieved in a preliminary study which demonstrated the compound to be a potential antiviral agent in reducing Infectious Bronchitis and New Castle Disease, two viral poultry diseases that have a significant economic impact to the poultry industry on an annual basis. (biospace.com)

This reference summarizes information about pharmaceuticals that can target infectious strains of coronaviruses to neutralize infections. (benthamscience.com)

Separately, the same integrated computational and experimental platform enabled the design and optimization of small-molecule viral protease inhibitors, resulting in the identification of several promising antiviral agents that are being further evaluated by academic and pharmaceutical partners. (osti.gov)

To do this ABIVAX leverages three technology platforms for drug discovery: antiviral, immune enhancing and polyclonal antibodies. (evotec.com)
Evotec is a drug discovery alliance and development partnership company focused on rapidly progressing innovative product approaches with leading pharmaceutical and biotechnology companies, academics, patient advocacy groups and venture capitalists. (evotec.com)
The United States sources 80% of its (active pharmaceutical ingredients) from overseas and a substantial portion of U.S. generic drug imports come either directly from China or from third countries like India that use (active pharmaceutical ingredients) sourced from China," the 2019 Review Commission Report says. (politifact.com)
A separate experiment focusing on a combination of 10 μM stenoparib and 0.5 μM remdesivir, an antiviral drug, resulted in over 80% inhibition of the alpha variant, which is substantially greater than the effect achieved with either drug alone, suggesting at least additive effects from combining the different mechanisms of activity of stenoparib and remdesivir. (nau.edu)
Therefore, these agents were administered with interferon and ribavirin as a three-drug cocktail to take advantage of interferon to prevent emergence of resistant variants. (medscape.com)

In this paper, the activity of antiviral agents from medicinal plants which have importance in Ayurveda, are discussed along with their source. (ijpsr.com)
An improved plaque reduction assay for antiviral activity was developed and used to examine extracts from sixty-one higher plants. (umn.edu)

As an antimicrobial and antiviral agent, lactoferrin is especially important in establishing an infant's immune system. (nbc29.com)

Includes a bibliography and appendix The book is primarily intended as a primary resource for medical research scholars and researchers in pharmaceutical companies and as a secondary resource for B.A.M.S. students, medical postgraduate students, and Ayurveda enthusiasts. (benthamscience.com)
Our reconstructed lung (r-Lung-SARS-CoV-2) platform is designed to assist pharmaceutical, biotech, and academic researchers in identifying antivirals for COVID-19. (who.int)

This includes four federal contracts that supported the discovery and development of the broadly active antiviral agent Molnupiravir. (grc.org)
Atea plans to continue to build its pipeline of antiviral product candidates through using its internal discovery capabilities augmented by in-licensing. (globenewswire.com)
We look forward to extracting further value from our antiviral discovery platform. (evotec.com)

Located at Ahmedabad (Gujarat, India), we have built up an advanced and robust infrastructural base that enables our team members to process highly effective pharmaceutical products in large quantity. (doctordanger.com)
Last year, Senate Finance Chairman Chuck Grassley wrote that "80% of (active pharmaceutical ingredients) are produced abroad, the majority in China and India. (politifact.com)
India is the third largest in the pharmaceutical industry. (arpb.in)

They are specific antiviral agents that shorten the course of the infection. (drweil.com)

Incorporated in the year 2002, we HEXAL PHARMACEUTICALS are reputed manufacturer, exporter and supplier of qualitative range of Soft Gelatine Capsules, Pharmaceutical Tablets, Pharmaceutical Capsules, Pharmaceutical Suspension, Pharmaceutical Syrup and Pharmaceutical Injection. (doctordanger.com)

Bioactive Properties and Pharmaceutical Potential (2nd ed. (wikipedia.org)
These initiatives include capitalizing on the growth potential of Quigley Pharma, a wholly-owned Ethical Pharmaceutical subsidiary, by continuing to develop natural-source potential prescription products for Systemic Radiation, Rheumatoid Arthritis, Avian Flu in animals and particularly, Diabetic Peripheral Neuropathy. (biospace.com)

He began his industrial career in 1994 at Procter and Gamble Pharmaceuticals where he led research teams on projects in the area matrix metalloprotease and kinase inhibition for application in both cancer and inflammation-based disorders. (grc.org)
ABIVAX's antiviral platform is based on its technology of inhibition mRNA biogenesis and its chemical library of more than one thousand small molecules. (evotec.com)

DORAL, Fla. , Feb. 2, 2023 /PRNewswire/ -- Amid a continuing supply chain crisis in the U.S. baby formula market, Australian health and wellness company, Care A2 Plus Pty Ltd ('Care'), and American Pharmaceutical Company, Gensco ® Pharma, have announced a partnership to bring the already established Australian Infant formula into millions of American homes. (nbc29.com)

Currently, Atea is focused on the development of orally-available antiviral agents for serious viral infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, and hepatitis C virus (HCV). (globenewswire.com)
It has also terminated a co-development agreement with ViroPharma of Exton, Penn-sylvania, for the antiviral agent Picovir (pleconaril), intended to treat the common cold. (pharmexec.com)
3) significant advances in the development of antiviral agents those that detect HCV viremia. (cdc.gov)

To answer these questions, we need to think about the role of academic biomedical research within our current economic system, its relationship with clinical medicine and the pharmaceutical industry, and the links between the scientific establishment and governments. (isj.org.uk)
She's been a consistent voice against Chinese-made pharmaceutical ingredients, co-introducing a bill last year that would require the Department of Defense to only buy U.S.-made medicine . (politifact.com)

Dive into the research topics of 'A simplified plaque reduction assay for antiviral agents from plants. (umn.edu)

Pharmaceutical companies have an obligation to put into place mechanisms for improving access to essential medicines for those who can not afford it, and governments have a responsibility to make essential medicines available in a sustainable manner. (who.int)

Alectorialic acid has been investigated for its antiviral properties. (wikipedia.org)
The active substances in Sambucol believed responsible for its effects are three flavonoids with antiviral properties. (drweil.com)

Progressively numerous studies on therapy of antivirals have been increased. (ijpsr.com)

ï ¶ Antacid and Anti-Ulcerant ï ¶ Analgesic, Anti-Inflammatory and Anti-Arthritics Based in Holzkirchen, Hexal produces some 1,000 pharmaceutical products based on more than 250 active ingredients. (doctordanger.com)
About 80% of active pharmaceutical ingredients come from overseas, but not just from China. (politifact.com)
The ibuprofen is what ends up stopping the pain, so it's the active pharmaceutical ingredient, but other ingredients are used in the pill, too. (politifact.com)
And the report focuses on active pharmaceutical ingredients, not general ones. (politifact.com)

Chloro-benzoic acid derivatives are widely used in the pharmaceutical industry. (iucr.org)

The Volgograd State Medical University and the Volgograd State Technical University offer degree-granting programs for the chemical, pharmaceutical industry and healthcare of the country. (medchem21.com)

Indian pharmaceutical industry is well known in producing "Generic" product at a very low cost. (arpb.in)

Anatomy14

Organisms46

Diseases23

Chemicals and Drugs87

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Phenomena and Processes38

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science3

Health Care4

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Compounds9

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Influenza12

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Drugs8

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Efficacy2

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H5N11

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20021

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20231

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