Pharmaceutical agents drug evaluation. Medical search. Frequent questions

It could also improve the effectiveness and reduce the cost of clinical drug trials if used as a method to select patients. (mcgill.ca)
In keeping with the tenets of personalized medicine, the introduced framework could lead to more effective medical care, decreased undesired secondary effects, and substantial reduction of pharmaceutical/clinical costs associated with clinical trials, thereby accelerating the creation-evaluation cycle of new therapeutic agents,´ says Iturria-Medina. (mcgill.ca)
Several pharmaceutical companies have already identified potent small molecule HBc inhibitors and preclinical and clinical studies have shown promising results. (plos.org)
The objectives of this program are to accelerate innovative drug discovery, the development of pharmacologic tools for basic and clinical research on mental disorders, or drug or alcohol addiction, and the development and validation of models for evaluating novel therapeutics for mental disorders. (nih.gov)
Moreover, evaluating and developing placebos for clinical trials is more challenging, particularly when the TCM compound formulations that contain rich color, special appearance, complex taste, and smell are different from the chemical drugs. (hindawi.com)
Nevertheless, similarity evaluation is essential for the successful developing of TCM placebo before clinical trials. (hindawi.com)
Tested were 19 clinical- the clinical outcome of patients treated with ribavirin or ly approved compounds from several major antiviral phar- other antiviral drugs in controlled trials is needed (5). (cdc.gov)
The recent epidemic has shown that knowledge is lack- allow rapid screening of commercially available antiviral ing regarding the clinical management and treatment of agents, enabling those with in vitro evidence of activity to infected patients. (cdc.gov)
Ribavirin (6-12), oseltamivir (8-10), fos- move expeditiously into clinical studies, since safety and carnet (8), intravenous immunoglobulin (8), and other pharmacokinetic information in humans is already avail- agents have been used to treat patients. (cdc.gov)
At the core of this list are journals that serve the world-wide scientific community covering Pharmacology, Pharmaceutical Medicine and Clinical Toxicology! (taylorandfrancis.com)
This volume of Frontiers in Clinical Drug Research - Dementia explores the current comorbidities that cause cognitive impairment and the current management alternatives for clinical cases of dementia. (benthamscience.com)
The volume is a timely update on dementia treatment for clinical physicians, neurologists, gerontologists, pharmaceutical and medicinal chemistry researchers, and physiologists. (benthamscience.com)
Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. (benthamscience.com)
Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. (benthamscience.com)
Despite the completion of several recent clinical trials using compounds showing neuroprotection in preclinical studies, pharmaceutical treatment strategies with proven clinical benefit are still lacking. (eurekaselect.com)
Given the utility of 18F isotope, [18F]labeling of functionalized trifluoromethyl arenes and heteroarenes including pharmaceutical agents is extremely sought after in clinical practice. (europa.eu)
The indictment alleges that Palacio participated in a scheme to falsify medical records to make it appear as though pediatric subjects made scheduled visits to Unlimited Medical Research, received physical exams from a clinical investigator, and took study drugs as required, when in fact these things had not occurred. (fda.gov)
Falsifying clinical trial data risks the health and safety of those who might later rely upon the drugs being tested," said Deputy Assistant Attorney General Arun G. Rao of the Justice Department's Civil Division. (fda.gov)
Reliable and accurate data from clinical trials is the cornerstone of FDA's evaluation of a new drug," said Special Agent in Charge Justin C. Fielder of the FDA Office of Criminal Investigations, Miami Field Office. (fda.gov)
Compromised clinical trial data could impact the agency's decisions about the safety and effectiveness of the drug under review. (fda.gov)
Many of the drugs currently in clinical use originate from natural products. (lu.se)
Key information for clinical evaluation presented in convenient digest form. (chipsbooks.com)
Persons with current infection who are not identified as cur- hepatitis C genotype 1 infection, in combination with pegylated rently infected will not receive appropriate preventive services, interferon and ribavirin, in adult patients with compensated liver clinical evaluation, and medical treatment. (cdc.gov)
Outbreaks have hospital in which the ICUs comprise Antibiotic susceptibility testing was been increasingly reported and most an internal medicine unit (10 beds), a determined using modified Kirby- of those outbreaks are caused by multi- coronary care unit (7 beds), a hepatol- Bauer method following the Clinical drug resistant (MDR) strains of this ogy unit (7 beds), a burns unit (10 beds) Laboratory Standards Institute guide- organism. (who.int)

Binders are pharmaceutical excipients which are polymeric in nature and possess cohesive as well as adhesive properties. (hindawi.com)
One of the consequences of this and subsequent changes to China pharmaceutical legislation, is that the NMPA (Chinese health authority) requires the submission of, and the pre-approval of, Drug Master Files (DMF) for ingredients and components of pharmaceutical (drug) products - including Active Pharmaceutical Ingredients (API), Excipients (EXC) and packaging materials. (cargill.com)
Natural excipients obtained from plants have diverse applications in drug delivery and they play different roles in dosage forms as binders, disintegrants, emulsifying agents and suspending agents. (ashdin.com)
Now a day's extensive studies are being conducted for finding the applicability of these natural excipients in the design of novel drug delivery systems [ 1 - 6 ]. (ashdin.com)

Our research programme in Pharmacy gives you the integrated, broad-based research training needed to exploit current advances in pharmaceutical and biological sciences and pharmacy practice. (kent.ac.uk)
We have carefully curated a range of Pharmaceutical Sciences journals for your selection. (taylorandfrancis.com)
Maximize the impact of your research in Pharmaceutical Sciences through increased visibility and discoverability when you publish with us! (taylorandfrancis.com)
Fields M., Abate M. A., Lan H., Leann L., Blommel M., Nabil H., Jame, K., Parent and Metabolite Opioid Drug Concentrations in Unintentional Deaths Involving Opioid and Benzodiazepine Combinations, Journal of Forensic Sciences 2015;60(4):950-56. (wvu.edu)
Canadian Society for Pharmaceutical Sciences. (aau.ac.ae)
Endodontics has always been indebted to pharmaceutical sciences to provide it with necessary analgesics and anti-inflammatory agents. (phcogj.com)
Pharmaceutical biotechnology / Miguel Camara -- Additional applications of microbiology in the pharmaceutical sciences / Denver Russell. (ewubd.edu)

The purpose of the IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans is to identify individual agents or environmental exposures that may be causes of human cancer, in order to provide a scientific basis for cancer prevention. (who.int)
This report represents the deliberations and conclusions of the fifth Advisory Group convened by the IARC Monographs Programme to advise on priorities for future evaluations. (who.int)
Since their inception, the IARC Monographs have based evaluations only on primary information published in the open scientific literature or primary information that is in the public domain, such as national governments' reports, which are freely available for consultation. (who.int)

Future development and approval of HBc-specific antiviral drugs will significantly accelerate the elimination of chronic hepatitis B. Additionally, a number of biological therapeutics are in preclinical evaluation and development, including immune modulators (e.g. (plos.org)
The National Institute of Mental Health (NIMH), the National Institute on Drug Abuse (NIDA), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) invite applications to advance the discovery, preclinical development, and testing of new, rationally based candidate medications to treat mental disorders, drug or alcohol addiction, and the development of novel ligands as tools to further characterize existing or to validate new drug targets. (nih.gov)
Publishes pharmaceutical research on formulations, preclinical development, drug delivery, processing and analytical technology and regulatory science. (taylorandfrancis.com)

The intelligent and human sensory evaluation results showed that the similarity values of HLG and its placebo about the CQAs at granule and solution status were all close to 1, which means that the two preparations have high similarities. (hindawi.com)
Hydroxypropyl methylcellulose (HPMC) is employed for a wide variety of pharmaceutical and food preparations. (aau.ac.ae)
C✩PharmDex ® 02010 dextrose monohydrate - Active Pharma Ingredient (API) for use as a carbohydrate source and osmotic agent in parenteral applications and oral preparations. (cargill.com)

Owing to their numerous pharmaceutical applications such as diluents, binders, disintegrant in tablets, and thickeners in liquid dosage forms, plant-derived polymers have gained considerable interest in recent years. (hindawi.com)
1991. Determination of plasticizers commonly used in pharmaceutical dosage forms by-high liquid chromatography. (cdc.gov)
Research Journal of Pharmaceutical Dosage Forms and Technology. (rjptonline.org)

A novel low molecular weight nanocomposite hydrogel formulation for intra-tumoural delivery of anti-cancer drugs. (nottingham.ac.uk)
Innovative pharmaceutical development based on unique properties of nanoscale delivery formulation. (edu.iq)
Basha BN, Prakasam K, Goli D. Formulation and evaluation of gel containing fluconazole-antifungal agent. (edu.iq)
Formulation and evaluation of melt in mouth tablets of Ondansetron HCl. (rjptonline.org)
4. Chanda R, Padmalata H, Venkatesh, Banerjee J. Formulation and Evaluation of Oral Disintegrating Tablets of Ondansetron Hydrochloride. (rjptonline.org)
Therefore, the availability of the CDE filing number for the formulation components is a critical milestone in the timeline and regulatory strategy for companies seeking Marketing Authorisations for the finished Drug Product in China. (cargill.com)

We sampled air and work surfaces for lactose (inactive ingredient in pharmaceuticals) and active pharmaceutical ingredients. (cdc.gov)
Inhalation exposures to active pharmaceutical ingredients were mostly below manufacturers' occupational exposure limits (if a limit was available). (cdc.gov)
Some employees were exposed to multiple active pharmaceutical ingredients, the effects of which are not well understood. (cdc.gov)
The surface sampling results and our observations also indicate the potential for personal clothing contamination with active pharmaceutical ingredients and the potential for take home exposure. (cdc.gov)

Synthesis and biological evaluation of new 3(2)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells. (amrita.edu)
Summaries of the toxicological and related information on which the safety assessments of the compounds were made, and of the identity and purity of food additives and flavouring agents will be published, respectively, by WHO in its Food Additives Series, and FAO, in its compendium of food additive specifications. (who.int)
The Committee's complex work in reaching an international consensus on the evaluation of these compounds means that no other body has comparable influence on public health decisions related to food safety. (who.int)
A scientific rationale is provided for estimating acceptable daily intake values (ADIs) for compounds with limited or no toxicity information to support pharmaceutical manufacturing operations. (cdc.gov)
These categories address all tion to cleaning validation and the resolution of atypical types of toxicological endpoints, including carcinogenic- extraneous matter investigations for relatively unstudied ity, immunotoxicity, neurotoxicity, and developmental compounds in APIs and finished pharmaceutical prod- toxicity. (cdc.gov)
Common among these 10 interactions of organic compounds, their power to detect excess cancer agents is the electrophilic nature of or their metabolites, with DNA and R 1 risk at particular sites. (who.int)

Some antiviral and antineoplastic agents and other pharmaceutical agents : views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Lyon, 12-19 October 1999. (who.int)

Mucoadhesive nanoparticles constitute one of the important novel drug delivery systems, which cause localization of the drug at the site of absorption. (ijpsonline.com)
Publishes research on the design, development, manufacture, and evaluation of conventional and novel drug delivery systems. (taylorandfrancis.com)

The drug discovery process requires that upwards of 10,000 molecules be screened for each new lead compound developed and relies upon an expensive and time consuming combination of in vitro cell culture-based and in vivo whole animal-based models to identify, validate, and ensure the safety of any resulting potential therapeutic agents. (inknowvation.com)

When the efficacy of a new pharmaceutical drug is tested, public health and safety must always take precedence over profit," said Acting U.S. Attorney Juan Antonio Gonzalez for the Southern District of Florida. (fda.gov)

The purpose of the National Cooperative Drug Discovery Group (NCDDG) Program is to create multidisciplinary research groups or partnerships for the discovery of pharmacological agents to treat and to study mental illness, drug or alcohol addiction. (nih.gov)
In this proposal, using a molecular hybridization approach, we describe the synthesis and pharmacological evaluation of new thalidomide and pomalidomide analogs within HADC inhibitory properties useful as new therapies for SCD treatment. (fapesp.br)

To overcome this limitation, oral sustained controlled release formulations are an attempt to release the drug slowly into the GIT and maintain an effective drug concentration in the systemic circulation for a long time. (ijpsonline.com)
Six hydrogel formulations containing prednisolone nanoparticles were prepared and characterized for particle size, entrapment efficiency, physical appearance, pH, drug content, spreadability test, viscosity, in-vitro drug release and ex-vivo diffusion. (edu.iq)
Drugs must be marketed as safe and therapeutically active formulations whose performance is consistent and predictable. (synokempharma.com)
These formulations were characterized using rheological, biopharmaceutical (drug release) and morphological (SEM) technique. (eurekaselect.com)

The aim of our research is to detect residues of four pain-killer drugs-naproxen, nimesulide, diclofenac, and ibuprofen-and an anti-epileptic drug-carbamazepine-in water samples we collected ( n = 8) from the Danube. (mdpi.com)
The evaluation of chemicals in food by the committee is a continuing activity, and four meetings (three on food additives and contaminants, and one on residues of veterinary drugs in food) are scheduled for 2006-2007. (who.int)
Proposal for regulatory risk mitigation measures for human pharmaceutical residues in the environment. (janusinfo.se)

Their very short maturation period and potential for producing significant quantities of pectin for medicinal application is an attractive niche for pharmaceutical researchers to investigate [ 13 , 14 ]. (hindawi.com)
The scope of the series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. (benthamscience.com)
New and better medicinal agents are being produced at an accelerated rate. (synokempharma.com)

With an average of 10,000 novel molecules that must be screened for each new lead compound developed, and an average of 10 to 15 years of research and development at a cost of up to $1B to manufacture one new drug, pharmaceutical companies must develop new testing regimens that provide more data at a lower cost in order to achieve the economics necessary to remain profitable. (inknowvation.com)
Extended artemisinin-based combination therapy (ACT) for treatment of uncomplicated Plasmodium falciparum malaria with already existing drug regimens, such as artemether-lumefantrine, might be effective in tackling the emerging ACT resistance. (biomedcentral.com)

In this investigation, the novel intelligent sensory evaluation technologies including the physical property testing apparatus, computer vision system, color card, and electronic tongue (E-tongue) were employed for characterization of CQAs of HLG and its placebo. (hindawi.com)

Zakeri-Milani P, Nezhadi SH, Barzegar-Jalali M, Mohammadi L, Nokhodchi A, Valizadeh H. Studies on dissolution enhancement of prednisolone, a poorly water-soluble drug by solid dispersion technique. (edu.iq)

Such evaluations are considered complementary to the rapid developments in research on the molecular genetics of human cancers thereby strengthening the basis for cancer control. (who.int)

ABSTRACT Multi-drug resistant (MDR) strains of Acinetobacter baumannii are responsible for an increasing number of opportunistic infections in hospitals. (who.int)

It has proven extremely difficult so far to eliminate HBV cccDNA by manipulating the host immune system or using existing antiviral drugs. (plos.org)
Prevention concluded that further in vitro testing of antiviral drugs exhibit in vitro anti-SARS-CoV activity. (cdc.gov)

The EPA evaluations include the type of cells affected and in vitro versus in vivo testing [51 Fed. (cdc.gov)
However, adverse outcomes in several in vitro tests may be considered in our evaluation. (cdc.gov)
Rosuvastatin calcium nanoparticles were prepared employing the precipitation technique and were characterized using Fourier-transform infrared spectroscopy, differential scanning calorimetry, X-ray powder diffraction, scanning electron microscopy and by estimating their zeta potential and in vitro drug release. (ijpsonline.com)
macologic classes: nucleoside analogs, interferons, The aim of this study was to investigate whether a panel protease inhibitors, reverse transcriptase inhibitors, and of currently available antiviral agents exhibit in vitro neuraminidase inhibitors. (cdc.gov)
Medline-indexed research on targeting and delivery of molecular and macromolecular drugs, carrier systems, and diagnostic, in vivo and in vitro applications. (taylorandfrancis.com)
With current in vitro screening assays now representing a $1.4B market with a predicted 12% annual growth rate, we believe we possess a product capable of significantly impacting the chemical/drug screening market and, here in particular, advancing our understanding of cytotoxic chemical biotransformations as they pertain to public health and consumer safety. (inknowvation.com)
In vitro permeation studies of nanoemulsions containing ketoprofen as a model drug. (edu.iq)
To evaluate the in vitro anti inflammatory potential of different parts of T.stans ethanolic extract and to compare the anti inflammatory activity with standard drug ibuprofen. (phcogj.com)

This is in contrast to many evaluations carried out both by national regulatory agencies and by various other programmes of the World Health Organization and other international organizations, which have access in confidence to proprietary information. (who.int)
The indictment also alleges that when Palacio was confronted by a Food and Drug Administration (FDA) regulatory investigator about her conduct, she made a false statement to that investigator. (fda.gov)
In 2019, China implemented an extensive overhaul of the regulatory requirements for drugs, resulting in a revised China Drug Administration Law, with an impact on domestic as well as foreign players in the Chinese pharmaceutical sphere. (cargill.com)
Regional offices and WHO Representatives also make use of the Committee's evaluations when advising Member states on food safety regulatory programmes. (who.int)
Improving the regulatory environmental risk assessment of human pharmaceuticals: Required changes in the new legislation. (janusinfo.se)

In addition, some intermediates were also included in the biological evaluation. (lu.se)

Publishes research on toxicology, risk assessment, implications of exposure to toxic agents, safety evaluations and practical relevance of toxicological data. (taylorandfrancis.com)

Polymeric materials from plants continue to be of interest to pharmaceutical scientists as potential binders in immediate release tablets due to availability, sustainability, and constant supply to feed local pharmaceutical industries. (hindawi.com)
All formulated tablets (F1-F18) passed the weight uniformity, drug content, hardness, and friability tests. (hindawi.com)
Even though pectin from citrus and mango peel have been investigated as potential binding agents in immediate release tablets, these two major sources of pectin have long maturity periods [ 9 - 11 ]. (hindawi.com)
However, air sampling results indicated that employees who clean or repair automatic dispensing machine cells, refill automatic dispensing machine canisters, clean manually-fed automated counters with canned air, and hand-fill hazardous drug prescriptions may be exposed to airborne dust from uncoated tablets. (cdc.gov)

Abate MA, Blommel ML. Self-assessment tool for drug information advanced pharmacy practice experience. (wvu.edu)
Dr. Blommel serves as one of the preceptors for the experiential drug information rotation in the WV CDHI for Doctor of Pharmacy degree students. (wvu.edu)
He will also teach students in various didactic courses in the School of Pharmacy and will participate in laboratories designed to give pharmacy students hands-on practice with electronic sources of drug information. (wvu.edu)
Health hazard evaluation report: evaluation of safety climate, health concerns, and pharmaceutical dust exposures at a mail order pharmacy. (cdc.gov)
The Health Hazard Evaluation (HHE) Program received a request from a mail order pharmacy. (cdc.gov)

Such polymers are biocompatible, inexpensive, readily available, and are superior to synthetic pharmaceutical additives due to low cost, low toxicity, and nonirritant nature. (hindawi.com)
More specifically, there has always been a need for anti-inflammatory phytotherapeutic agents as the commercially available synthetic anti inflammatory drugs have their own limitations due to undesirable side effects. (phcogj.com)

or each of these agents, carcinogenicity in rats and/or mice, els, differences in exposure con- there was sufficient evidence of car- for example for the liver (aflatoxins, ditions between studies in animals cinogenicity from studies in rats and/ trichloroethylene [TCE], and vinyl and in humans, or limitations in Part 1 · Chapter 1. (who.int)

The NIOSH Hazardous Drug Committee has reviewed all new FDA drug approvals and new drug warnings for the period January 2014 through December 2015. (cdc.gov)

More than 300 reports in all categories of drugs -- from alternative medicines to vaccines and serums. (chipsbooks.com)

All drugs have toxic side effects, but some exhibit toxicity at low doses. (cdc.gov)

The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. (webmd.com)
However, BVM was released faster than SUR, with their combination (SUM) to appearing to reduce delivery, probably due to interactions between the drugs or with the polymeric matrix. (eurekaselect.com)
Adverse reactions and drug interactions are a dynamic part of drug therapy. (chipsbooks.com)
Drug interactions with grapefruit juice are well documented. (medlineplus.gov)

Quality assurance is a good practice in the manufacture of pharmaceutical products, as it is the process of vouching for integrity of products to meet the standard for the proposed use. (synokempharma.com)

However, the current standard antiviral therapies are not sufficient for a 'complete' cure of chronic hepatitis B. Additional novel drugs are urgently needed in order to eliminate chronic HBV infection. (plos.org)

It also made several general recommendations, in particular on the principles of safety assessment of flavouring agents and enzymes produced by genetically modified organisms. (who.int)

This is accomplished by evaluating the strength of the published scientific evidence for carcinogenicity of agents and environmental factors or circumstances to which humans are exposed. (who.int)

2002]. OELs in this range are typically established for potent or toxic drugs in the pharmaceutical industry. (cdc.gov)
This makes the use of their pectin in the pharmaceutical industry as an excipient unpopular. (hindawi.com)
This has inspired the scientific community, pharmaceutical industry, and government agencies to explore various strategies to achieve this ambitious goal in the next 15 years. (plos.org)
Purpose: The intent of this document is to provide audit technique guidelines for IRS agents and managers examining the credit for increasing research activities claimed by taxpayers in the pharmaceutical industry. (irs.gov)
Quality control is an essential operation of the pharmaceutical industry. (synokempharma.com)
Nature contains an endless supply of natural products and has for long been a source of inspiration for the pharmaceutical industry. (lu.se)

Currently, nanoparticles technology is well known and it used to augment the rate of drug dissolution and considerably increased bioavailability. (edu.iq)

Antibacterial agents are essential drugs for human health and welfare. (ijpsr.com)

Doctor en Ciències Químiques per la Universitat de València en 1984. (uji.es)

9. Sumithra M, Prabhabanik A. A Prospective Study of Drug Utilization and Evaluation of Gastro Intestinal Agents. (rjptonline.org)

All these improvements can be used for radiosynthesis of [18F]trifluoromethylation of pharmaceutical candidates to facilitate drug development, especially for CNS diseases. (europa.eu)

Hence, novel potent analgesic and anti-inflammatory drugs without considerable side effects from the natural sources are under evaluation. (phcogj.com)

Its innovation-driven drug discovery processes ensure the health and well-being of people around the world. (cadilapharma.com)

To provide healthcare workers and healthcare facilities information on identifying hazardous drugs so that proper handling can be performed to reduce worker exposures. (cdc.gov)
Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. (webmd.com)
A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. (webmd.com)
Clin-Alert 2001 provides an easy-to-use, quick and reliable reference that will be useful to healthcare professionals working with pharmaceuticals. (chipsbooks.com)

HA286 trade name] is indicated in combination with another antiretroviral agent for the treatment of Human Immunodeficiency Virus (HIV) infected adults and adolescents over 12 years of age. (who.int)

Quality assurance and control of pharmaceutical products is very important for achieving a therapeutically active and standard product. (researchgate.net)

Destinations for doctoral graduates include university academic departments, research institutes and leading pharmaceutical and biotechnological companies. (kent.ac.uk)
Rather, it is designed to reduce burden for all stakeholders by (1) providing an overview of the drug development process in branded pharmaceutical companies for agents, (2) identifying audit areas that have the highest probability for errors, and (3) providing guidance on the essential information agents need to make a determination as to qualified research expenditures. (irs.gov)
The West Virginia Center for Drug and Health Information (WV CDHI), in operation for over 40 years (known previously as the West Virginia Drug Information Center), has as its mission service provision, student/practitioner education, and research/scholarly activities to optimize access to and the appropriate use of drug and therapeutics information to improve patient care. (wvu.edu)
2.US Food and Drug Administration (FDA) Center for Drug Evaluation and Research (CDER). (webmd.com)
International Journal of Drug Development and Research. (edu.iq)
Indonesia Natural Research Pharmaceutical Journal. (rjptonline.org)
The natural polymers which were characterized in the present research work have showed good flow properties and suitable physico chemical properties like low moisture content which enables low chance of microbial growth, high swelling index indicates high swellability and goodwater retention capacity there by enhanced permeation of drug for longer periods of time. (ashdin.com)
NEW YORK, Sept. 28, 2021 /PRNewswire/ - The Lung Cancer Mutation Consortium (LCMC) kicks off its fourth study, facilitated by the Lung Cancer Research Foundation (LCRF), examining targeted drugs given as single agents and combinations as neoadjuvant therapies matched to specific genetic mutations. (lungcancerresearchfoundation.org)
Environmental risks of pharmaceutical mixtures in aquatic ecosystems: reflections on a decade of research. (janusinfo.se)
These health-based limits are used to sup- impurity and degradant levels in drugs ( ICH, 1997a, port both occupational health and quality programs in 2002a,b,c, 2003 ), with acceptable amounts for residual pharmaceutical research, development and manufactur- solvents in pharmaceuticals, so-called ``permitted daily ing operations. (cdc.gov)

The Department of Justice will continue to work with its partners at the Food and Drug Administration to investigate and prosecute anyone who endangers the public for financial gain. (fda.gov)
1 US Food and Drug Administration. (ispe.org)
The same concept has been used by the US Food and Drug Administration (FDA) to establish ``thresholds of regulation'' for indi- rect food additives and adopted by the Joint FAO/WHO Expert Committee on Food Additives for flavoring substances. (cdc.gov)

Professor Guangxiang (George) Luo discusses recent advances in antiviral drug development and hepatitis B immunization which hold great promise for achieving the WHO goal of eliminating viral hepatitis by 2030. (plos.org)
3) significant advances in the development of antiviral agents those that detect HCV viremia. (cdc.gov)

1986. Evaluation of a new approach to the safety assessment of biomaterials. (cdc.gov)
The Committee's work identifies and, if possible, quantifies the public health significance of additives and flavouring agents in food through a scientific assessment of risk. (who.int)
Member States therefore need to be provided with valid information on both the general aspects of risk assessment and the specific evaluations of food additives and flavouring agents covered in this report. (who.int)

Using pTIF subtypes, drugs can be designed for a patient's unique gene expression profile and phenotypic brain characteristics, which is a major advancement in personalized medicine. (mcgill.ca)
As with every patient, the initial source for determining the etiology of a patient's complaint involves an accurate history and a physical evaluation. (medscape.com)
The first step in treatment is to objectively determine the patient's approximate drug tolerance level because patients often inaccurately estimate the amount of drug they have been taking. (medscape.com)

The agents and exposures listed will be considered during the period 2000-2005. (who.int)
Employees were concerned about possible health effects from exposures to hazardous drugs and pharmaceutical dust, and communication and other workplace safety climate issues. (cdc.gov)
No employees reported changes in their health consistent with exposures to hazardous drugs. (cdc.gov)

The Committee made recommendations on the safety of several food additives and flavouring agents and prepared or reviewed specifications for a number of them. (who.int)

Active substances detected in surface water in Hungary today include pain and anti-inflammatory agents and antiepileptics, as wastewater treatment mechanisms cannot remove these micropollutants. (mdpi.com)
Carbamazepine is a drug of choice for the treatment of partial and tonic-clonic seizures. (researchgate.net)
To overcome these detractions and develop an improved tier 1 screening system that reduces the cost and time required for new compound evaluation, 490 BioTech proposes to develop a panel of multiple continuously bioluminescent human cell lines that will permit the simultaneous monitoring of each line to ascertain both the individual effects of compound treatment as well as the downstream effects of a compound's biotransformed metabolic breakdown products in real-time. (inknowvation.com)
Sickle cell disease (SCD) is a one of the most prevalent genetic and hematologic disease worldwide, which has the hydroxyurea (HU) as the only available drug to the treatment. (fapesp.br)
Moreover, some individuals do not respond to HU-treatment, justifying the search for new drugs. (fapesp.br)
However, given the history of cardiotoxicity among anti-malarial drugs structurally similar to lumefantrine, the potential effect of extended artemether-lumefantrine treatment on the electrocardiographic (ECG) QTc interval is of high concern. (biomedcentral.com)
Treatment of withdrawal syndromes is identical for withdrawal from all sedative-hypnotics because all drugs in this category, including barbiturates, sleeping pills, benzodiazepines, and alcohol, exhibit cross-dependence. (medscape.com)

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Anthropology, Education, Sociology and Social Phenomena1

Clinical24

Excipients4

Sciences7

IARC Monographs3

Preclinical3

Preparations3

Dosage forms3

Formulation6

Active Pharmaceuti4

Compounds6

Antineoplastic Agents1

Novel drug deliver2

Therapeutic agents1

Efficacy1

Pharmacological2

Formulations4

Residues3

Medicinal3

Regimens2

Characterization1

Solid dispersion1

Complementary1

Abstract1

Antiviral drugs2

Vitro8

Regulatory5

Biological evaluation1

Toxicological1

Tablets4

Pharmacy5

Synthetic2

Exposure1

Hazardous Drug1

Vaccines1

Toxicity1

Interactions4

Practice1

Infection1

Enzymes1

Carcinogenicity1

Industry6

Dissolution1

Antibacterial1

19841

Utilization1

Candidates1

Potent1

Discovery1

Healthcare4

Antiretroviral1

Therapeutically active1

Research10

Food and Drug Admin3

Advances2

Assessment3

Patient's3

Exposures3

Safety1

Treatment7