Personal genomics and medicine. Medical search. Frequent questions

Public Health Genomics (2014) 17 (3): 158-168. (karger.com)
Angela Brand, MD PhD MPH (USA) is Full Professor in the Department of International Health and Founding Director of the Institute for Public Health Genomics at the Faculty of Health, Medicine and Life Sciences (FHML) as well as Professorial Fellow at UNU-MERIT (United Nations University - Maastricht Economic and Social Research Institute on Innovation and Technology) at Maastricht University, The Netherlands. (unu.edu)
She is also Dr. T.M.A. Pai Endowment Chair on Public Health Genomics, Head of the Department of Public Health Genomics at the School of Life Sciences as well as Adjunct Professor at the Prasanna School of Public Health at Manipal University, India. (unu.edu)
She has been the pioneer of Public Health Genomics in Europe and coordinated and established successfully this field in more than 15 EU Member States within the last years (PHGEN). (unu.edu)
She has been founder and Editor-in-Chief (2009-2017) of Public Health Genomics, the leading international journal focusing on the responsible and timely translation of genome-based knowledge and technologies into public health, health policies, and health systems. (unu.edu)
Currently she is Member of the Board of Directors of the Digital Health Society ( www.thedigitalhealthsociety.com ) enabled by the European Connected Health Alliance (ECHAlliance, www.echalliance.com), Director of the European Centre for Public Health Genomics (ECPHG), and also Expert on „Big Data" of the International Consortium Personalised Medicine (IC PerMed, www.icpermed.eu) jointly coordinated by the European Commission, over 26 European Member States and Canada. (unu.edu)
Her research focus is on Public Health Genomics, Personalised Medicine & Personal Health & Care, Translational Research, AI and Big Data Analytics for Public Health, PPP, Innovation Management, Data Governance & Cooperative Health Ecosystem (e.g. (unu.edu)
Strategies, actions, and outcomes of pilot state programs in public health genomics, 2003-2008. (cdc.gov)
Public health genomics advances the translation of genome-based discoveries into disease prevention and population health. (cdc.gov)
CDC's Office of Public Health Genomics in the Center for Surveillance, Epidemiology, and Laboratory Services is hosting a webinar series focusing on unique topic related to genetics and genomics. (cdc.gov)

This second meeting builds on last year's presentations showing a significant milestone in human genetics - the first production of "personal genomes. (medbioworld.com)
Patient advocates and caregivers also cautioned against overly-optimistic projections of the benefits of using genetics in a new era of personalized medicine. (aaas.org)
Furthermore, 'precision medicine,' it has been argued, 'is much more than just genetics' (Lewis, Reference Lewis 2015 ). (cambridge.org)
My teaching covers the concepts and methodologies of population genetics and comparative genomics, and personal genomics and medicine. (23andme.com)
August 12, 2022 - Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron. (mssm.edu)
Because of the broad application of these biochemical methods, this conference is aimed at specialists and interested parties from a wide range of scientific fields: Agricultural and nutritional sciences, biochemistry, biotechnology, genetics, molecular biology, medicine and pharmacy. (leibniz-institut.de)
Diagnosis and management of glycogen storage disease type I: a practice guideline of the American College of Medical Genetics and Genomics. (medscape.com)

While these biomarkers can be useful in diagnosing or screening some medical conditions, or in developing drugs or predicting their effectiveness, understanding the bigger picture of genomic medicine is in its infancy. (aaas.org)
Despite some early implementation of genomic medicine globally, there is a lack of rigorous, large-scale assessments of medical specialists' current practice and continuing education needs. (frontiersin.org)
We conducted semi-structured qualitative interviews with 32 education providers and 86 non-genetic medical specialists about current genomic medicine practice and need for continuing education. (frontiersin.org)
and, preferences for future roles and models of care in genomic medicine and for continuing education. (frontiersin.org)
Survey data will provide evidence for education providers to inform development of education which meets learner needs and contributes to a medical workforce that is literate in genomics and more confident to competently practice genomic medicine. (frontiersin.org)
different approaches to the practice of genomic medicine will be needed. (frontiersin.org)
Therefore, there is little evidence available to inform the design and development of system-wide educational or training activities to support non-genetic medical specialists in acquiring the skills, confidence and competence they need to appropriately integrate genomic medicine into their clinical practice. (frontiersin.org)
however, exploitation of the data made available through advances in genomic medicine, imaging, and a wide range of mobile health applications or connected devices is hampered by numerous historical, technical, legal, and political barriers. (biomedcentral.com)
Yes: Personalized medicine, individualized medicine and genomic medicine are also common names. (beckershospitalreview.com)
I think it's going to happen in stepwise fashion," said David B. Goldstein, PhD, director of the Institute for Genomic Medicine at ColumbiaUniversityMedicalCenter in New York City. (beckershospitalreview.com)
Knowledge integration at the center of genomic medicine. (cdc.gov)
Genomic Medicine Year in Review 2019: What's Hot for Public Health Impact? (cdc.gov)
Advances in genomic medicine continue at a fast and steady pace. (cdc.gov)
I'm privileged today to speak with Sekar Kathiresan from the Broad Institute, who heads up the Center for Genomic Medicine at Massachusetts General Hospital, which is not even a year old, and who also is on the faculty at Harvard Medical School. (medscape.com)

Dr. Downing joined BMIR in 2016 as a Clinical Assistant Professor of Medicine. (stanford.edu)
Yes.In his 2015 State of the Union address, President Obama announced the Precision Medicine Initiative, dedicating $215 million in fiscal year 2016 to advancing genomics. (beckershospitalreview.com)
In August 2016, we published a point-counterpoint viewpoint asking a crucial question that has been on the minds of researchers, health care providers and the public health community: "will precision medicine improve population health? (cdc.gov)

A knowledge base for tracking the impact of genomics on population health. (cdc.gov)

Predictive genomics is at the intersection of multiple disciplines: predictive medicine, personal genomics and translational bioinformatics. (wikipedia.org)

Pathway Genomics Inc., a U.S. based genetic testing company, announced the immediate availability of its personal Genetic Health Report. (news-medical.net)

Furthermore, the downstream effect of identifying disease-relevant biomarkers allow for improvements to monitoring disease progression and response-to-treatment, where the implementation of these results into clinical decision support systems (CDSS) facilitate personalised medicine and outcomes. (wikipedia.org)
This meeting will address the issues of individual genomes being part of research and routine clinical medicine within the next few years. (medbioworld.com)
In order to advance precision medicine, detailed clinical features ought to be described in a way that leverages current knowledge. (nature.com)
He practices Internal Medicine for the reward of caring for patients and to inspire research, mining clinical data sources to inform recommendations for medical decision-making. (stanford.edu)
As Director of the Quantitative Sciences Unit (QSU), she manages a group of faculty and PhD and Master's level staff who collaborate with clinical and translational investigators throughout the School of Medicine. (stanford.edu)
Dr. Downing is a physician (Internal Medicine) and an expert in clinical decision support, electronic health records, clinician burnout, and applications of artificial intelligence in healthcare. (stanford.edu)
His research focuses on the intersection of machine learning, computational immunology, and translational medicine with the overarching goal of accelerating translation of immune response-based diagnostics and therapies to clinical practice across a broad spectrum of inflammatory diseases, including infections, autoimmune diseases, organ transplant, cancers, and vaccines. (stanford.edu)
Many providers today already embrace different aspects of personalized care disparately, but how many providers simultaneously prioritize genomics, clinical analytics and leading-edge patient engagement solutions? (techrepublic.com)
December 20, 2022 - Using machine learning and clinical data from electronic health records, researchers at the Icahn School of Medicine at Mount Sinai in New York constructed an in silico, or computer-derived, marker for coronary artery disease (CAD) to better measure clinically important characterizations of the disease. (mssm.edu)
Although students expressed skepticism over the clinical utility of sometest results, they expressed significant enthusiasm immediately after receivingtheir personal genetic analysis, and were particularly interested in results suchas drug response and carrier testing. (biomedcentral.com)
Clinical genomics-genome structure and variation. (medlineplus.gov)
I did internal medicine (clinical cardiology) training, and I was a chief resident in medicine at Mass General. (medscape.com)

WIKIMEDIA, WILLIAM CROCHOT Mountain View, California-based genomics testing company 23andMe aims to take advantage of its wealth of genetic data to develop drugs. (the-scientist.com)
This Springfield, MO-based laboratory was established in 2015, but it has only shifted its focus from molecular research to personal health, wellness and ancestry DNA testing recently, which means that it doesn't have DNA databases that are as extensive as the likes of 23andMe and AncestryDNA . (t3.com)

In August 2019, the All of Us Research Program announced the funding of a nationwide resource to provide genetic counseling support to one or more million participants in the precision medicine cohort in the United States. (cdc.gov)

However, preliminary examples of predictive genomics for personalising healthcare include: using an individual's gene expression data to monitor progress to treatment, or using the genomic profile of the P450 drug metabolising system of individuals to assist dosage and selection. (wikipedia.org)
A blog devoted to discussing best practices and questions about the role of genomics and precision health in disease prevention, health promotion and healthcare. (cdc.gov)
Precision, stratified or personalized medicine denotes emerging medical models that use molecular diagnostics, genetic sequencing, cellular analysis and pharmacogenomics to tailor individual healthcare treatment and prevention. (cambridge.org)
Sequencing healthy individuals will inevitably reveal new findings for that individual, only some of which will have actual health implications," said lead author Jason Vassy , an HMS assistant professor of medicine at Brigham and Women's and primary care physician at the VA Boston Healthcare System. (harvard.edu)
Medicine and healthcare are undergoing profound changes. (biomedcentral.com)
It's time healthcare got a little more personal. (techrepublic.com)
Direct-to-consumer (DTC) personal genomics companies provide public access toindividualized genetic testing outside the context of traditional healthcare systems.For a fee, consumers may submit a saliva specimen for analysis to obtain genetic riskinformation on a broad spectrum of health conditions and behavioral traits. (biomedcentral.com)
At the 17th Conference on Retroviruses and Opportunistic Infections (CROI), ViiV Healthcare presented new data across its broad range of investigational and current medicines for the treatment of HIV/AIDS. (news-medical.net)

In the applications of predictive genomics below, these complex diseases either lack or are lacking reliable diagnostics for disease. (wikipedia.org)
Precision medicine has also been used for diagnostics and treatment decision-making for other conditions, such as epilepsy, certain childhood diseases, some pregnancy conditions, cardiology and infectious disease. (beckershospitalreview.com)

Current research in genomics and pharmacogenomics is increasingly highlighting the need to move towards stratified disease descriptions and individualized treatment plans. (firebaseapp.com)
Thecourse, GENE 210 'Genomics and Personalized Medicine' aimed to educate students on theanalysis and interpretation of individual genome data as it relates to disease risk,pharmacogenomics, and human ancestry [ 21 ]. (biomedcentral.com)
Pharmacogenomics is the application of genomics technology to the development of specific drugs and its relationship with dentistry is a recent area of research. (bvsalud.org)
Pharmacogenomics is the application of genomics technology to the discovery and development of drugs. (bvsalud.org)

This public/private translational consortium developed methods for oncology biomarkers to advance personalized therapy and medicine. (ucl.ac.uk)

The main motive was to contribute their data to scientific research, followed closely by their interest to find out disease risks and personal traits. (karger.com)
Furthermore, the strong interest in genetic research participation signals an underexplored personal utility of genomic testing which needs to be both better understood and better harnessed. (karger.com)
The leading genome research centers and scientists have publicly recognized that these are the core enabling goals for the next decade genomics research. (springer.com)
The National Human Genome Research Institute (NHGRI) has echoed this need through its vision for genomics research (Collins et al. (springer.com)
The past decade has witnessed a revolution in the field of human genomics research. (springer.com)
Dr. Khatri is a faculty member in Institute for Immunity, Transplantation and Infection (ITI) and Center for Biomedical Informatics Research (BMIR) in Department of Medicine at Stanford University. (stanford.edu)
Today, modern medicine is no longer conceivable without genome research. (leibniz-institut.de)
The research mostly entails genomics. (lu.se)
Authorized users (registered students and staff) at Lund University may still only download individual items, i.e. one (1) article, chapter or ebook for personal use, for educational, scientific or research purposes. (lu.se)
Authorized users (registered students and staff) at Lund University may download and print individual items solely for educational, personal, scientific, or research purposes. (lu.se)

October 25, 2022 - A new approach to cancer immunotherapy that uses one type of immune cell to kill another-rather than directly attacking the cancer-provokes a robust anti-tumor immune response that shrinks ovarian, lung, and pancreatic tumors in preclinical disease models, according to researchers at the Icahn School of Medicine at Mount Sinai in New York. (mssm.edu)

Rapid advances in technologies in the field of genomics such as high throughput DNA sequencing, big data processing by machine learning algorithms and gene-editing techniques are expected to make precision medicine and gene-therapy a greater reality. (bmj.com)
The lectures will give an overview of the different forms and the importance of DNA and RNA, modern trends in the analysis of gene data, the use of the results for biology, medicine, social and engineering sciences. (leibniz-institut.de)
Many personal characteristics, such as height, are determined by more than 1 gene. (medlineplus.gov)
I address these questions in two steps: firstly, I discuss epistemological implications of the development of Genomics, understood as a data-intensive science, by delving into the theoretical commitments of the concept of gene and the notion of circular causality. (bvsalud.org)

Most people are familiar with the story of the origins of genetic medicine in the writings of individuals like Francis Galton, leading to the eugenic belief that the human race could be improved by discouraging or preventing the reproduction of persons with perceived undesirable traits. (aaas.org)

Precision medicine, also called personalized medicine, helps your doctor find your unique disease risks and treatments that will work best for you. (cdc.gov)

You might have heard the terms "precision medicine" and "precision health" and wondered how they relate to you. (cdc.gov)
Precision health is broader-it includes precision medicine but also approaches that occur outside the setting of a doctor's office or hospital, such as disease prevention and health promotion activities. (cdc.gov)
By virtue of treating each person's condition as unique, personal genomics and personalized medicine require health profession. (firebaseapp.com)
The Shift From Personalized Medicine to Precision Medicine and Precision Public Health: Words Matter! (cdc.gov)
Although individualized treatment has the potential of reducing health care costs, panelists said, insurers have to decide whether or when to pay for new tests, treatments or procedures involving personalized medicine. (aaas.org)
By taking genetic, environmental and lifestyle factors into account, and by relying heavily on big data analysis, precision medicine aims to identify risk factors and biomarkers that predict health outcomes and help choose the best treatment for the patient. (cambridge.org)
Here, in an effort to bridge this gap, Electronic Health Records (EHRs) of individual patients are connected to a heterogeneous knowledge network called Scalable Precision Medicine Oriented Knowledge Engine (SPOKE). (nature.com)
In an attempt to address one of the most critical challenges in precision medicine, a handful of recent studies has started to merge basic science-level data with phenotypic data encoded in electronic health records (EHRs) to get a deeper understanding of disease pathogenesis and their classification to enable rational and actionable medical decisions. (nature.com)
In the discussion of population health, precision medicine can be leveraged to identify an individual's risk of developing a certain disease. (beckershospitalreview.com)
She is Paediatrician, Specialist in Public Health Medicine, holds a PhD in pathology, a Master of Public Health (MPH) from Johns Hopkins University, USA, and received her habilitation from the University of Bremen, Germany, focusing on Health Technology Assessment. (unu.edu)
Four of those are proactive health-focused, and another four are on personalised medicine. (t3.com)
Viral hepatitis C gets personal--the value of human genomics to public health. (cdc.gov)
Two recent systematic scoping reviews explore the use and limitations of digital tools in public health surveillance and their applications to the pandemic response Digital health tools offer increasing potential for substantial benefits to medicine and public health. (cdc.gov)
This customized and innovative personal genetic health report contains information on more than 70 health conditions, including pharmacogenetics (prescription medication response), propensity for complex disease, and carrier status (pre-pregnancy health). (news-medical.net)

Specifically, predictive genomics deals with the future phenotypic outcomes via prediction in areas such as complex multifactorial diseases in humans. (wikipedia.org)
Precision medicine, incorporating personalized medicine, is an emerging medical model that holds great promise for improving the prevention, diagnosis and treatment of many diseases. (cambridge.org)
While it is thought that precision medicine will also lead to the 'prevention' of many diseases, such data gathering efforts will also likely lead to new therapeutic strategies, entailing new ways of thinking about the role and experience of the patient. (cambridge.org)
Precision medicine - a system for disease prevention and treatment that takes individual variability in genes, lifestyle and the environment into account - is emerging as a promising approach in the fight against cancer and other serious diseases. (beckershospitalreview.com)

We were surprised to see how many ostensibly healthy individuals are carrying a risk variant for a rare genetic disease," said Heidi Rehm , HMS associate professor of pathology at Brigham and Women's and director of the Laboratory for Molecular Medicine at Brigham and Women's. (harvard.edu)
The lab also investigates linking omics data with cellular and tissue data in the context of computational pathology, imaging genomics & radiogenomics. (stanford.edu)

We've researched and ranked the best genomics books in the world, based on recommendations from world experts, sales data, and millions of reader ratings. (shortform.com)

Included are protocols from Humana's book series Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology , and Neuromethods , as well as from a vast number of Laboratory Handbooks, such as The Biomethods Handbook, The Proteomics Handbook , and the Springer Laboratory Manuals . (lu.se)

This SWOT analysis and the developed guiding reference highlight the need for scientists/clinicians to be well-versed in ethics and data protection policy to advance sport and exercise genomics without compromising the privacy of athletes and the efforts of international sports federations. (bmj.com)
The future success of precision medicine, however, depends on the establishment of large databases that collate diverse data, including family genealogies, disease histories, drug sensitivities and genomic data. (cambridge.org)
This study builds upon these concepts and utilizes a heterogeneous network called Scalable Precision Medicine Oriented Knowledge Engine (SPOKE) to interpret data stored in EHRs of more than 800,000 individuals at The University of California, San Francisco (UCSF). (nature.com)
The high-throughput - next generation sequencing (HT-NGS) technologies are currently the hottest topic in the field of human and animals genomics researches, which can produce over 100 times more data compared to the most sophisticated capillary sequencers based on the Sanger method. (springer.com)
Quantitative data were collected through a questionnaire sent by email to members of the Ankara Chambers of Medicine and the Ankara Chambers of Veterinary Medicine. (who.int)

However, there is another, more positive and humane origin of genetic medicine that preceded the eugenics movement by centuries, Dr. Cowan noted. (aaas.org)
Genetic Medicine: How Does it Play In South Dakota? (epidemix.org)
Funding Network of Applied Genetic Medicine (3175, Côte-Ste-Catherine, Montréal, Canada) and French Association Against Myopathies (1, Internationale Avenue - 91002 Evry, France). (bmj.com)

Representation in genomics studies has been dominated by populations descending from Europe. (nature.com)

For Techonomy, she covers the technologies of personal genomics, the quantified self movement, and DIY biology that are poised to transform the practice of medicine and the business of biotechnology. (techonomy.com)

The investments are based on the belief that the medical establishment is moving toward the routine sequencing of every patient's genome in the quest for 'precision medicine,' a course for prevention and treatment based on the special, even unique characteristics of the patient's genes. (techonomy.com)
The recent technological advances in genomic sequencing power have precipitated significant precision medicine projects by major states. (cambridge.org)
In a new paper published June 26 in the Annals of Internal Medicine by investigators at Harvard Medical School and Brigham and Women's Hospital , along with collaborators at Baylor College of Medicine, report the results of the four-year, NIH-funded MedSeq Project , the first-ever randomized trial conducted to examine the impact of whole genome sequencing in healthy primary care patients. (harvard.edu)
Such techniques included the 10x Genomics linked-read based SParse Isoform Sequencing (SPIso-seq), as well as Loop-Seq, or Tell-Seq. (bvsalud.org)

The basic premise of precision medicine is that a physician can look at an individual's genotypic information to understand his or her disease on a molecular level and use clues in genetic variation to identify the most effective course of action. (beckershospitalreview.com)

There is therefore an urgent need for guiding references for sport and exercise genomics to allow the necessary advancements in this field of sport and exercise medicine, while protecting athletes from any invasion of privacy and misuse of their genomic information. (bmj.com)

For most of human history, medicine has been personalized using the knowledge available at the time. (aaas.org)
To this end, we focused on the complete inventory of human olfactory receptor coding regions as a model for personal receptor repertoires. (biomedcentral.com)

This raises questions about concerns relating to potential risks of DTC genomics users and users' understanding of genetic information including their awareness of privacy risks. (karger.com)

Recent developments in precision medicine have given rise to the development of a genetic risk score, known as Polygenic Risk Score (PRS), which can estimate the genetic risk of developing a CAD. (deccanchronicle.com)
Genomics is thus becoming central to the development of an effective system of 'personalized' medicine. (cambridge.org)

Dr. Cowan, the Janice and Julian Bers Professor in the Department of History and Sociology of Science at the University of Pennsylvania, opened the meeting by noting that personalized medicine is not a new field. (aaas.org)

iPSC have great potential for regenerative and therapeutic medicine. (ucl.ac.uk)

To date, the success of predictive genomics has been dependent on the genetic framework underlying these applications, typically explored in genome-wide association (GWA) studies. (wikipedia.org)
Therefore, the ability for predictive genomics to succeed also depends upon other related areas such as the functional annotation of the genome (ENCODE). (wikipedia.org)
The BRC-funded Cancer Genome Engineering (CAGE) Facility develops and provides TALE- and CRISPR-based genome engineering technologies for targeted genetic and epigenetic reprogramming to advance personal and medical genomics. (ucl.ac.uk)

Dr. Desai joined the Department of Medicine at Stanford University in 2009. (stanford.edu)
He continued his work as a postdoc in radiology at Stanford and then established his lab in the department of medicine in biomedical informatics. (stanford.edu)

Finally I argue that the future potential of 'personalized' medicine crucially depends on 'collective' participation of informed citizens. (cambridge.org)
I conclude that much of the potential efficacy of 'personalized' medicine actually depends on 'collective' participation. (cambridge.org)

The final survey captures not only levels of experience, practice of genomics and preferences for education but also the challenges around engaging with education. (frontiersin.org)
The practice of precision medicine can be both reactive and preemptive. (beckershospitalreview.com)

Chemicals and Drugs1

Analytical, Diagnostic and Therapeutic Techniques and Equipment12

Psychiatry and Psychology1

Phenomena and Processes7

Disciplines and Occupations17

Anthropology, Education, Sociology and Social Phenomena12

Humanities2

Information Science8

Named Groups1

Health Care5

Geographicals1

Public Health G10

Genetics7

Genomic medicine14

20163

Impact of Genomics1

Bioinformatics1

Pathway Genomics1

Clinical12

23andMe2

20191

Healthcare8

Diagnostics2

Pharmacogenomics4

Translational1

Research10

20221

Gene4

Traits1

Called personalized medicine1

Health14

Diseases4

Pathology2

Recommendations1

Molecular Medicine1

Data5

Genetic medicine3

Populations1

Biotechnology1

Sequencing4

Individual's1

References1

Human2

Risks1

Development2

Janice1

Therapeutic1

Genome3

Department2

Depends2

Practice2