• enzyme
  • A study was conducted of the effects of 10 hypolipidaemic agents on peroxisomal and microsomal enzyme activities in primary cultures of rat hepatocytes. (semanticscholar.org)
  • Treatment with compounds such as Wy-14,643, tiadenol, nafenopin, BR-931, clofibrate and mono-(2-ethylhexyl)phthalate induced cyanide-insensitive palmitoyl-CoA oxidation (a specific peroxisomal marker enzyme), a polypeptide with a molecular weight of 80,000 associated with peroxisome proliferation, and carnitine acetyltransferase activity, after 70 h of culture. (semanticscholar.org)
  • The results indicate that hypolipidaemic agents which stimulate hepatic peroxisomal enzyme activities also induce novel form(s) of cytochrome P-450 with high specificity towards lauric acid hydroxylation. (semanticscholar.org)
  • Proteins
  • We have expertise in peroxisomal transport proteins (especially ABC transporters) involved in lipid catabolism and have also identified novel regulators of lipid breakdown via genetic screens. (rothamsted.ac.uk)
  • metabolic
  • The heterogenous biochemical response during peroxisome normalization could be due to several factors including a possible requirement for restoration of peroxisomal structural integrity for maximum activation of certain metabolic pathways. (biomedsearch.com)