Spinal cordCranialAnterior hornSensoryRootsMyastheniaCentral and peripheralNeuropathiesWeaknessAffect the peripheralReceptorsSkeletal muscleDisorders of the periphRelease of acetylcholineAutonomicNeuropathyAxonEndingsImpulsesOccursLower motorAbnormalitiesSynapsesAffectsPolyneuropathyPlantigrade stanceConductionClinicalRecurrent larynAtrophyNeurologyThymus glandMotor nerveNMDsFibersPathologicDiagnosisNeurologicDemyelinationContractionRadial nerveProximalNeuronalSynapticOccurTrigeminalElectromyographyProcessesBranchesDeficitsInvolvesSynapseSpineDiagnose
Spinal cord13
- Lou Gehrig's disease involves the degeneration of nerve cells in the brain and spinal cord. (gwdocs.com)
- Introduction to Symptoms of Brain, Spinal Cord, and Nerve Disorders Disorders that affect the brain, spinal cord, and nerves are called neurologic disorders. (msdmanuals.com)
- Therefore, true weakness results only when one or more part of this pathway―brain, spinal cord, nerves, muscles, or the connections between them―is damaged or diseased. (msdmanuals.com)
- The impulse travels along a sensory nerve to the spinal cord. (msdmanuals.com)
- The impulse crosses a synapse (the junction between two nerve cells) between the sensory nerve and a nerve cell in the spinal cord. (msdmanuals.com)
- The impulse crosses from the nerve cell in the spinal cord to the opposite side of the spinal cord. (msdmanuals.com)
- The impulse crosses a synapse between the nerve fibers in the spinal cord and a motor nerve, which is located in the spinal cord. (msdmanuals.com)
- The impulse travels out of the spinal cord along the length of the motor nerve. (msdmanuals.com)
- Neuromuscular diseases (NMDs) are diseases involving the motor nuclei of the cranial nerves and anterior horn cells of the spinal cord, the peripheral nerves, the neuromuscular junction, and/or muscle itself. (qxmd.com)
- Structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves can result in a range of symptoms. (web.app)
- The spine consists of 26 bones referred to as vertebrae, that protects and support the spinal cord and nerves. (crgconferences.com)
- Administration of gene therapy viruses into skeletal muscle, where distal terminals of motor and sensory neurons reside, has been shown to result in extensive transduction of cells within the spinal cord, brainstem, and sensory ganglia. (frontiersin.org)
- The peripheral nervous system refers to parts of the nervous system outside the brain and spinal cord. (medscape.com)
Cranial7
- Symptoms are symmetric cranial nerve palsies accompanied by a symmetric descending weakness and flaccid paralysis without sensory deficits. (merckmanuals.com)
- Some diseases may also affect cranial nerves causing dysphonia (change in the bark), difficulty swallowing, prehending or chewing food. (ndsr.co.uk)
- Binocular horizontal diplopia (images displaced horizontally) is usually due to disease of the medial or lateral rectus muscle, the neuromuscular junction, or the nerves supplying these muscles (e.g., cranial nerves III or VI). (eyewiki.org)
- Vertical diplopia (images displaced vertically) can be due to involvement of extraocular muscles, neuromuscular junction (e.g., myasthenia gravis), or cranial nerves (e.g. (eyewiki.org)
- It includes the cranial nerves, spinal nerves and their roots and branches, peripheral nerves, and neuromuscular junctions. (medscape.com)
- Ganglia may be divided into sensory ganglia of spinal nerves (spinal or posterior root ganglia) and cranial nerves and autonomic ganglia. (medscape.com)
- Similar ganglia that are also found along the course of cranial nerves V, VII, VIII, IX, and X are called sensory ganglia of these nerve. (medscape.com)
Anterior horn3
- West Nile virus) have been associated with acute flaccid paralysis (AFP)-a clinical syndrome of rapidly progressive flaccid paralysis typically caused by dysfunction of the anterior horn cells, peripheral motor nerves or nerve roots, neuromuscular junction, or muscle-La Crosse virus has not been identified as a cause ( 3 , 4 ). (cdc.gov)
- Neuromuscular disorders (NMDs) are diseases that originate from pathologic changes in anterior horn cells (AHCs), peripheral nerves, neuromuscular junctions (NMJs), and/or muscles. (biomedcentral.com)
- The anterior horn cells, although technically part of the central nervous system (CNS), are sometimes discussed with the peripheral nervous system because they are part of the motor unit. (medscape.com)
Sensory21
- Peripheral nerve injuries may result in loss of motor function, sensory function, or both. (medscape.com)
- The future in peripheral nerve injuries lies in maximizing motor and sensory recovery after nerve injury. (medscape.com)
- For optimal outcome after surgery, knowledge of motor and sensory fascicular topography within the nerve is essential to ensure correct alignment of the motor and sensory fascicles. (medscape.com)
- Clinically, both demyelination and axonal degeneration result in disruption of sensory function, motor function, or both in the injured nerve. (medscape.com)
- Depending on the severity and degree of nerve injury, recovery of function occurs with remyelination and with axonal regeneration and reinnervation of the sensory receptors, motor end plates, or both. (medscape.com)
- With closed traumatic injuries or restoration of nerve continuity, axons may regenerate and thus reinnervate the motor end plates and sensory receptors. (medscape.com)
- Depending on the severity of nerve injury, recovery of motor and sensory function is variable. (medscape.com)
- they commonly cause fluctuating muscle weakness with no sensory deficits. (merckmanuals.com)
- The peripheral nervous system includes the motor and sensory neurons, neuromuscular junctions, peripheral nerves, and muscles. (floridaortho.com)
- For example, special nerve endings in the skin (sensory receptors) enable people to sense pain or a change in temperature. (msdmanuals.com)
- This sensory information is sent to the brain, and the brain may send a message to the muscle about how to respond. (msdmanuals.com)
- The impulse crosses a synapse in the thalamus to nerve fibers that carry the impulse to the sensory cortex of the cerebrum (the area that receives and interprets information from sensory receptors). (msdmanuals.com)
- The speed at which motor or sensory nerves carry impulses is measured in nerve conduction tests. (ankurahospitals.com)
- Muscles contain the synaptic connection between lower motor neurons and muscle fibers, i.e., the neuromuscular junction (NMJ), as well as specialized sensory nerve endings (e.g., muscle spindles). (frontiersin.org)
- Generation of a nerve impulse (action potential) of a sensory neurone occurs as a result of a stimulus such as light, a particular chemical, or stretching of a cell membrane by sound. (medscape.com)
- Sensory ganglia of spinal nerves are fusiform swellings situated on the posterior root of each spinal nerve just proximal to the root's junction with a corresponding anterior root. (medscape.com)
- The sensory (afferent) division carries sensory signals by way of afferent nerve fibers from receptors in the central nervous system (CNS). (medscape.com)
- The somatic sensory division carries signals from receptors in the skin, muscles, bones and joints. (medscape.com)
- Nerve fibers of the PNS are classified according to their involvement in motor or sensory, somatic or visceral pathways. (medscape.com)
- Mixed nerves contain both motor and sensory fibers. (medscape.com)
- In the late 1960s, neurophysiologic testing allowed the classification of CMT into 2 groups, one with slow nerve conduction velocities and histologic features of a hypertrophic demyelinating neuropathy (hereditary motor and sensory neuropathy type 1 or CMT1) and another with relatively normal velocities and axonal and neuronal degeneration (hereditary motor and sensory neuropathy type 2 or CMT2). (medscape.com)
Roots5
- Myasthenia gravis Polyradiculoneuritis is inflammation of the nerve roots. (wikipedia.org)
- Feline neuromuscular diseases may be classified according to their location as those involving peripheral nerves and/or nerve roots, those involving the neuromuscular junction, and those that involve muscle (1). (vin.com)
- Brachial plexus avulsion produced by severe thoracic limb abduction with secondary stretching or tearing of nerve roots is a commonly occurring peripheral nerve injury of cats. (vin.com)
- Sacroiliac fracture/dislocation, sacral fracture, or caudal vertebral fracture/luxation may result in damage to the sixth and seventh lumbar and first 2 sacral nerve roots. (vin.com)
- Feline malignant lymphoma may involve nerve roots or peripheral nerves. (vin.com)
Myasthenia9
- Myasthenia gravis is a condition that results from either an inherited or an acquired reduction of acetylcholine receptors of neuromuscular junctions. (vin.com)
- We have neurologists that specialize in peripheral neuropathy, myopathies, Lou Gehrig's disease (Amyotrophic Lateral Sclerosis) and myasthenia gravis. (gwdocs.com)
- Myasthenia gravis (MG) is a relatively rare acquired, autoimmune disorder caused by an antibody-mediated blockade of neuromuscular transmission resulting in skeletal muscle weakness and rapid muscle fatigue. (medscape.com)
- These diseases include myasthenia gravis or certain specified neuromuscular junction disorders, primary disorders of muscle, and secondary myopathies. (qxmd.com)
- The main symptom of myasthenia gravis is muscle weakness. (thewitfire.in)
- Myasthenia gravis is an autoimmune disorder that affects neuromuscular transmission. (thewitfire.in)
- Myasthenia gravis is a condition that results from an error in the transmission of nerve impulses to the muscles. (thewitfire.in)
- Congenital myasthenia gravises are inherited disorders that impair the transmission of nerve signals through the neuromuscular junction. (thewitfire.in)
- Congenital myasthenia syndromes are categorized based on the parts of the neuromuscular junction that are affected. (thewitfire.in)
Central and peripheral4
- Birman cat distal polyneuropathy is an inherited disorder caused by decreased numbers of myelinated axons in the central and peripheral nervous systems. (wikipedia.org)
- Diseases of the central and peripheral nervous system. (harvard.edu)
- SLE affects many organ systems, including the central and peripheral nervous systems and muscles. (medscape.com)
- It is distributed throughout the central and peripheral nervous systems. (medscape.com)
Neuropathies2
- Single case reports exist of a variety of peripheral neuropathies in cats. (vin.com)
- Neuromuscular diseases affect the peripheral nervous system and either affect the peripheral nerves (neuropathies), neuromuscular junction (junctionopathies) or the muscle itself (myopathies). (ndsr.co.uk)
Weakness14
- Signs include weakness, ataxia, and muscle atrophy. (merckvetmanual.com)
- Symptoms include decreased or absent reflexes and muscle tone, weakness, or paralysis. (wikipedia.org)
- Dancing Doberman disease progresses over a few years to rear leg weakness and muscle atrophy. (wikipedia.org)
- Distal symmetric polyneuropathy symptoms include atrophy of the distal leg muscles and the muscles of the head, and rear limb weakness. (wikipedia.org)
- We defined AFP as a clinical syndrome of rapid-onset extremity weakness, sometimes accompanied by weakness in a facial or respiratory muscle that is flaccid (i.e., without any upper motor neuron signs in the affected areas suggestive of central nervous system motor tract pathology) ( 4 ). (cdc.gov)
- Upper motor neuron signs included increased muscle tone or spasticity, increased deep-tendon reflexes, the presence of Babinski and Hoffmann signs, abnormally slow finger or toe taps out of proportion to weakness, or a clear upper motor neuron pattern of weakness (e.g., hemiparesis involving the face, arm, and leg). (cdc.gov)
- Neuromuscular junction disorders ("junctionopathies") result in a variety of clinical signs that range from flaccid paralysis to exercise-induced weakness. (vin.com)
- Cervical ventroflexion is a dramatic sign of generalised neuromuscular weakness in cats. (vin.com)
- Weakness refers to loss of muscle strength. (msdmanuals.com)
- Children's with neuromuscular disorders often experience muscle pain or weakness, muscle twitching, cramping, numbness and tingling, muscle stiffness causing joint deformities and sometimes difficulty in swallowing and breathing. (stgeorgeorthopaedics.com.au)
- Inflammatory myopathies are a group of muscle diseases that involve chronic muscle inflammation and muscle weakness. (stgeorgeorthopaedics.com.au)
- Patients with inflammatory myopathies may have slow but progressive muscle weakness that begins in the proximal muscles. (stgeorgeorthopaedics.com.au)
- The goal of treatment is to minimize the muscle weakness and prevent the onset of myasthenic crises. (thewitfire.in)
- Dogs with acute onset neuromuscular disease will commonly start with signs of weakness and a short strided gait in the pelvic limbs which will then affect the thoracic limbs and over 24-72 hours they progress to being unable to walk with a flaccid tetraparesis or tetraplegia (absence of voluntary movement). (ndsr.co.uk)
Affect the peripheral1
- Its use is supported by a series of randomized and controlled trials assessing diseases that affect the peripheral nerve, neuromuscular junction, and skeletal muscle. (nursingcenter.com)
Receptors4
- The autoimmune attack occurs when autoantibodies form against the nicotinic acetylcholine postsynaptic receptors at the neuromuscular junction of skeletal muscles (see the image below). (medscape.com)
- Normal neuromuscular junction showing a presynaptic terminal with a motor nerve ending in an enlargement (bouton terminale): Synaptic cleft and postsynaptic membrane with multiple folds and embedded with several acetylcholine receptors. (medscape.com)
- At the neuromuscular junction (where nerves connect to muscles), the impulse crosses from the motor nerve to receptors on the motor end plate of the muscle, where the impulse stimulates the muscle to move. (msdmanuals.com)
- Acetylcholine binds to acetylcholine receptors in the muscle and activates it, which causes it to contract. (thewitfire.in)
Skeletal muscle1
- [ 1 , 2 ] Although the chief target of the autoimmune attack in most cases is the skeletal muscle nicotinic acetylcholine receptor (nAChR), other antigenic targets that are components of the neuromuscular junction (NMJ) have also been implicated. (medscape.com)
Disorders of the periph2
- Our medical team provides comprehensive evaluation of patients with disorders of the peripheral nerves, muscles and the neuromuscular junction. (gwdocs.com)
- Neuromuscular medicine has to do with disorders of the peripheral nervous system (PNS) and its connections with the central nervous system. (floridaortho.com)
Release of acetylcholine1
- BoNT hinders neural transmission by stalling the release of acetylcholine at the neural endplate and inhibits muscle contraction. (researchsquare.com)
Autonomic3
- The autonomic nervous system is the part of the nervous system concerned with the innervation of involuntary structures, such as the heart, smooth muscle, and glands within the body. (medscape.com)
- Autonomic ganglia, which are often irregular in shape, are situated along the course of efferent nerve fibers of the autonomic nervous system. (medscape.com)
- The visceral motor division, also known as the autonomic nervous system, carries signals to glands, cardiac muscle, and smooth muscle. (medscape.com)
Neuropathy2
- Laryngeal Hemiplegia in Horses Laryngeal hemiplegia is a progressive neuropathy of the recurrent laryngeal nerve, leading to atrophy and dysfunction of the cricoarytenoideus dorsalis muscle, an important abductor for the. (merckvetmanual.com)
- Sphingomyelinase-deficiency polyneuropathy' hyperchylomicronemia-associated neuropathy, hyperoxaluric peripheral neuropathy, hypertrophic polyneuropathy, and Birman cat distal polyneuropathy are examples of inherited polyneuropathies. (vin.com)
Axon9
- A nerve is composed of neural tissue (axon) and connective tissue. (medscape.com)
- In myelinated nerve fibers, each axon is surrounded by the endoneurium. (medscape.com)
- Peripheral nerve damage of either the myelin or axon is mediated by an immune cascade involving cytokines, monocytes, and complement-fixing antibodies. (nursingcenter.com)
- The condition is caused by a defect in the genes for proteins that is found in the structure and function of either the peripheral nerve axon or the myelin sheath. (stgeorgeorthopaedics.com.au)
- Perhaps the most obvious feature of a neuron is the long branch called an axon that ventures far from the cell body to connect with other neurons or muscles. (neurosciencenews.com)
- The branch that is responsible for carrying the message or signal to the outside of the nerve cell or neuron is called the axon. (scopeheal.com)
- The axon is one, and it is the zone of the motor neuron that ends in the area of contact of the muscle, in a structure of the oval form of about 32 microns of extension. (scopeheal.com)
- When the axon enters the muscle, it branches into axonal terminals, and this region adjacent to these terminals, in the muscle fiber membrane, is called the motor plate. (scopeheal.com)
- This is not surprising given the strong evidence for interaction between myelin and axon gene expression in development and after experimental nerve lesions. (medscape.com)
Endings1
- When injected into a muscle, viruses are close to nerve endings for longer periods and at higher concentrations than when systemically injected. (frontiersin.org)
Impulses2
- Specially-trained physicians use information from a patient's history and physical exam, along with test results that analyze electrical impulses between muscles and nerves. (floridaortho.com)
- This neuromuscular junction plays an elementary role in transmitting nerve signals or impulses from the motor neuron to the muscle fiber that causes muscle contraction. (scopeheal.com)
Occurs3
- Cerebral palsy occurs in infants or in early childhood that affects body movements, balance, posture, and muscle coordination. (stgeorgeorthopaedics.com.au)
- This disruption occurs at the neuromuscular junction, the place where nerve cells connect with muscles. (thewitfire.in)
- It is called the neuromuscular junction that occurs between the motor neuron and the muscle fiber. (scopeheal.com)
Lower motor2
- Polyneuropathy usually involves motor nerve dysfunction, also known as lower motor neuron disease. (wikipedia.org)
- Each of these neuromuscular diseases will produce lower motor neuron (LMN) disease, however significant variations in clinical signs may occur. (vin.com)
Abnormalities1
- Mutations that reduce, but don't eliminate, Perlecan can cause Schwartz-Jampel syndrome, in which patients experience neuromuscular problems and skeletal abnormalities. (neurosciencenews.com)
Synapses3
- Broken nerves eventually led to the synapses retracting," said study senior author Troy Littleton, Menicon Professor in MIT's Departments of Biology and Brain and Cognitive Sciences. (neurosciencenews.com)
- Instead, they were investigating a hypothesis that Perlecan might help organize some of the protein components in synapses that fly nerves develop to connect with muscles. (neurosciencenews.com)
- Synapses and neuromuscular junctions are physiologically similar processes. (scopeheal.com)
Affects6
- Dancing Doberman disease primarily affects the gastrocnemius muscle in Dobermans. (wikipedia.org)
- It affects muscles involved in everything from limb movement to breathing. (gwdocs.com)
- Botulism is poisoning that is due to Clostridium botulinum toxin and that affects the peripheral nerves. (merckmanuals.com)
- A neuromuscular disease is a disorder that affects the muscles and its nervous control. (stgeorgeorthopaedics.com.au)
- Charcot-Marie-Tooth Disease (CMT) is a genetic nerve disorder that affects your peripheral nerves. (stgeorgeorthopaedics.com.au)
- The disease primarily affects skeletal muscles, which are responsible for walking. (thewitfire.in)
Polyneuropathy4
- Polyneuropathy in dogs and cats is a collection of peripheral nerve disorders that often are breed-related in these animals. (wikipedia.org)
- Polyneuropathy indicates that multiple nerves are involved, unlike mononeuropathy. (wikipedia.org)
- Polyneuropathy is caused by stretching or compression of nerves near bone by xanthomas, which are lipid deposits. (wikipedia.org)
- This is an inflammatory condition affecting multiple peripheral nerves (polyneuropathy) in dogs and is considered to be the equivalent of Guillain-Barre syndrome in man. (ndsr.co.uk)
Plantigrade stance2
- Affected cats often have unilateral or bilateral tibial nerve dysfunction, evident as a plantigrade stance. (merckvetmanual.com)
- It is caused in part by prolonged hyperglycemia (high blood sugar) and results in dysfunction of one or both tibial nerves and a plantigrade stance (down on the hocks). (wikipedia.org)
Conduction3
- Laboratory tests include electromyography (EMG), Single Fiber-EMG, as well as routine and advanced nerve conduction studies. (gwdocs.com)
- What is nerve conduction study? (ankurahospitals.com)
- Now a large and ever increasing number of genetic subtypes has been described, and major advances in molecular and cellular biology have clarified the understanding of the role of different proteins in the physiology of peripheral nerve conduction in health and in disease. (medscape.com)
Clinical4
- Diagnosis is based on clinical findings, laboratory evidence of diabetes mellitus, and nerve biopsy. (merckvetmanual.com)
- It includes a board-certified neuromuscular neurologist, a board-certified pulmonologist, a neuromuscular nurse practitioner, and a clinical research coordinator as well as a speech-language pathologist, physical and occupational therapists, a dietitian, and a social worker who is an ALS specialist. (gwdocs.com)
- The importance of utilizing BoNT injections targeted at the neuromuscular junction has been confirmed by clinical studies on the iliopsoas and biceps brachii muscles. (researchsquare.com)
- Journal of clinical neuromuscular disease , 10 (1), 29-34. (psu.edu)
Recurrent laryn1
- Injury to the recurrent laryngeal nerve (RLN) can result in impairment of all three laryngeal functions. (qxmd.com)
Atrophy3
- Peripheral nerve and muscle diseases result in varying degrees of paresis, muscle atrophy, hyporeflexia, and hypotonia. (vin.com)
- Some primary muscle disorders may be characterised by muscle hypertrophy rather than atrophy. (vin.com)
- There is no specific treatment and, despite being an immune-mediated disease, steroids do not appear to be effective and instead increase the risk of aspiration pneumonia and speed of muscle atrophy. (ndsr.co.uk)
Neurology1
- The Department of Neurology & Rehabilitation Medicine at The George Washington University Medical Faculty Associates is a premier program that offers patients high quality, compassionate healthcare for conditions ranging from back pain and sleep disturbances to stroke and the most complex neuromuscular disorders. (gwdocs.com)
Thymus gland1
- Researchers have learned more about the structure of the neuromuscular junction and the thymus gland , leading to better diagnosis and improved treatment options. (thewitfire.in)
Motor nerve1
- Motor nerve axons carry nerve signals from the brain to the muscle cells, while the synaptic cleft acts as a transducer to convert electrical signals to chemical signals. (thewitfire.in)
NMDs2
- Neuromuscular disorders (NMDs) are chronic illnesses that adversely impact the lives of patients and their families. (biomedcentral.com)
- The Pediatric Quality of Life™ 3.0 Neuromuscular Module (PedsQL™ 3.0 NMM) was designed to assess health-related quality of life (HRQoL) among children with NMDs. (biomedcentral.com)
Fibers3
- Groups of nerve fibers are surrounded by the perineurium to form fascicles, and groups of fascicles are surrounded by the internal and external epineurium. (medscape.com)
- The motor (efferent) division carries motor signals by way of efferent nerve fibers from the CNS to effectors (mainly glands and muscles). (medscape.com)
- Motor nerves contain motor fibers. (medscape.com)
Pathologic2
- Pathologic findings in nerves consist of demyelination with remyelination, axonal degeneration, or both. (merckvetmanual.com)
- Pathologic findings in peripheral nerves consist of demyelination or remyelination and axonal degeneration. (merckvetmanual.com)
Diagnosis3
- These specialists are internationally recognized for their expertise in diagnosis and management of these complex diseases of the muscles. (gwdocs.com)
- Definitive diagnosis is made from histopathological examination of nerve root biopsies. (ndsr.co.uk)
- Diagnosis and characterization of neuromuscular disorders have traditionally advanced faster than therapeutics. (psu.edu)
Neurologic1
- There are more than 600 types of neurologic and neuromuscular diseases that can affect your nervous system. (web.app)
Demyelination1
- Peripheral nerve injury may result in demyelination, axonal degeneration, or both. (medscape.com)
Contraction3
- These signals then induce muscle contraction. (thewitfire.in)
- This effect finally results in muscle contraction. (scopeheal.com)
- Thus, the neuromuscular junction is a connection or synapse between the somatic motor neuron and the muscle fiber, where the transformation of a chemical impulse to an electrical stimulation causes the contraction of the muscle fiber. (scopeheal.com)
Radial nerve2
- In a study of the US National Inpatient Sample database, Lad et al reported higher rates of median, ulnar, and radial nerve injuries as compared with brachial plexus injuries. (medscape.com)
- Mononeuropathies of radial nerve and sciatic nerve occur in cats following mechanical blows, gunshot wounds, fractures, pressure and stretching. (vin.com)
Proximal1
- When the nerve injury is very proximal (eg, in brachial plexus injury or sciatic nerve injury), nerve regeneration may not occur quickly enough to permit muscle reinnervation. (medscape.com)
Neuronal3
- Neuromuscular disorders are the conditions caused by impaired neuronal activity of the nerves that control the voluntary muscle activities. (stgeorgeorthopaedics.com.au)
- method to introduce genetic material into select neuronal populations is by virus administration into muscle, which is the focus of this review. (frontiersin.org)
- Neuronal function is complex and involves numerous processes in nerve transmission. (medscape.com)
Synaptic3
- Proteins on the muscle side of the synaptic connection remained, but the neuron side of the connection withered away. (neurosciencenews.com)
- This part of the muscle fiber attached interacts with the motor neuron is a synapse between the "end synaptic bulbs" present in the motor neuron and the "endplate of the engine" located in the muscle fiber. (scopeheal.com)
- The synaptic channel is an invaginated membrane, which is the space for the synaptic bulbs to approach the sarcolemma of the muscle fiber. (scopeheal.com)
Occur2
- Myogenic involvement can occur with disease of the superior rectus, inferior rectus, superior oblique, or inferior oblique muscles alone or in combination. (eyewiki.org)
- A pupil involving third nerve palsy may occur with subarachnoid hemorrhage from ruptured posterior communicating artery aneurysm. (eyewiki.org)
Trigeminal1
- Pain in the V1 and V2 divisions of the trigeminal nerve can suggest an intracranial (e.g., cavernous sinus) or intraorbital lesion. (eyewiki.org)
Electromyography1
- Our board-certified physicians are fellowship trained in electromyography and in the treatment of neuromuscular diseases, with more than 16 years of combined experience. (floridaortho.com)
Processes2
- A modified Sihler's procedure was completed on 15 quadratus lumborum muscles to visualize the intramuscular arborization areas in terms of the inferior border of the 12th rib, the transverse processes of L1-L4, and the iliac crest. (researchsquare.com)
- For successful transgene expression, viruses administered into muscle must undergo a series of processes, including host cell interaction and internalization, intracellular sorting, long-range retrograde axonal transport, endosomal liberation, and nuclear import. (frontiersin.org)
Branches2
- Each nerve cell has a cell body and branches. (scopeheal.com)
- These branches that transfer a signal to the nerve cell are called numerous dendrites. (scopeheal.com)
Deficits1
- Hyporeflexia, hypotonia, ataxia and proprioceptive positioning deficits are most characteristic of peripheral nerve disease. (vin.com)
Involves2
- Moving a muscle usually involves communication between the muscle and the brain through nerves. (msdmanuals.com)
- Polymyositis involves inflammation of the skeletal muscles of both sides of the body. (stgeorgeorthopaedics.com.au)
Synapse2
- That suggested that a lack of Perlecan might not be a problem at the synapse, but instead causes trouble along axons due to its absence in the extracellular matrix surrounding nerve bundles. (neurosciencenews.com)
- However, the neuromuscular junction is a specific synapse between the motor neuron and the muscle fiber. (scopeheal.com)
Spine2
- The brain, spine, nerves, or muscles can all be the source of nervous system problems. (ankurahospitals.com)
- This keeps you from stretching the nearby nerves, ligaments, and muscles that may cause discomfort.Numerous conditions that can affect the spine anywhere from the neck to the lower back. (crgconferences.com)
Diagnose1
- To diagnose neuromuscular disorders we have invested in an advanced electrodiagnostic laboratory that has achieved the highest possible accreditation with exemplary status from the American Association of Neuromuscular & electrodiagnostic Medicine. (gwdocs.com)