Peripheral blood leukocyte. Medical search. Frequent questions

Peripheral blood leukocyte mitochondrial DNA content and risk of lung cancer. (cdc.gov)

[ 4 , 6 ] Guidelines from Infectious Diseases Society of America (IDSA) recommend confirmatory testing for babesiosis with a blood smear or PCR. (medscape.com)
Blood smear showing Babesia species in erythrocytes. (medscape.com)
Peripheral smear showing babesiosis. (medscape.com)
Blood smear patient with CML c. (horiba.com)
The results of the leukocyte differential count showed the same cell types found in the morphology of the peripheral blood smear and bone marrow aspiration. (horiba.com)
There was no difference in the leukocyte differential count parameters between both hematology analyzers and had a significant positive correlation with the morphology of the peripheral blood smear and bone marrow aspiration. (horiba.com)
Blood smear (original magnification ×2000) in patient with May-Hegglin anomaly (MHA) demonstrates characteristic giant platelet with poorly defined granulation. (medscape.com)
Although rapid confirmation of genetic diagnosis is mandatory, patients in whom APL is suspected (on the basis of clinical presentation and peripheral blood smear results) should be immediately hospitalized and their case managed as a medical emergency. (medscape.com)

The elements were evaluated by the total number of peripheral leukocyte, granulocyte and lymphocyte ratio and lymphocyte subsets. (scirp.org)
The number of leukocyte subsets, granulocyte and lymphocyte were also regulated by dose dependent manner. (scirp.org)
It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. (biolegend.com)

Babesiosis is usually diagnosed by microscopic examination of Giemsa-stained or Wright-stained thin or thick blood smears. (medscape.com)
Wright-stained or Giemsa-stained peripheral blood smears reveal intraerythrocytic ring forms with a central pallor. (medscape.com)
Hence, these cells, which can be seen in bone marrow aspirates and in peripheral smears, have been called megaloblasts. (medscape.com)

Total leukocyte counts exhibited changes mainly in neutrophils and lymphocytes that can contribute to the BVDV immunosuppression, thus accounting for some of the intergroup differences. (unimi.it)
90% of binding of human lymphocytes to high endothelial venules (HEV) in frozen sections of peripheral, but not mucosal lymphoid tissue. (bdbiosciences.com)
Profile of peripheral blood lymphocytes analyzed by flow cytometry. (bdbiosciences.com)
Human peripheral lymphocytes were stained with anti-human 62L (clone DREG-56) APC/Fire™ 810 (filled histogram) or mouse IgG1, ĸ APC/Fire™ 810 isotype control (open histogram). (biolegend.com)
CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. (biolegend.com)
Flow cytometric estimation of the apoptotic marker CD95 in peripheral neutrophils, lymphocytes and monocytes was done for 18 infants with non-oedematous protein energy malnutrition (PEM) and 12 oedematous ones, on hospital admission and after supervised nutritional rehabilitation, and compared with 12 matched controls. (who.int)

This coincided with less fungal association with leukocytes, especially neutrophils. (frontiersin.org)
The lower neutrophil number in murine blood only partially explains insufficient infection and filamentation control, as spiking with murine neutrophils had only limited effects on fungal killing. (frontiersin.org)

Peripheral blood polymorphonuclear leukocyte (PMN) counts were determined. (cdc.gov)
Blood PMN counts were significantly increased from baseline at 8 and 22 hours. (cdc.gov)
Total white blood cell counts decreased shortly after infection then increased with time. (usda.gov)
CD95 counts in the 3 types of white blood cells were significantly higher in PEM infants and showed improvement after nutritional rehabilitation yet not reaching the control values. (who.int)

We also observed host-dependent differences for interaction of platelets with C. albicans , showing enhanced platelet aggregation, adhesion and activation in murine blood. (frontiersin.org)
In 1909, May described the presence of leukocyte inclusions and large platelets in an asymptomatic young woman. (medscape.com)
In 1945, Hegglin described a man and his 2 sons who were healthy but had a triad consisting of thrombocytopenia, giant platelets, and leukocyte inclusions. (medscape.com)

VSV infection triggered rapid differentiation of blood monocytes into immature dendritic cells as well as their apoptosis, which depended on caspase 3/7 activation. (karger.com)
Effect of infection with BHV-1 on peripheral blood leukocytes and lymphocyte subpopulations in calves with subclinical BVD / V. Molina, M.A. Risalde, P.J. Sánchez-Cordón, M. Pedrera, F. Romero-Palomo, C. Luzzago, J.C. Gómez-Villamandos. (unimi.it)
Results indicate that the peripheral blood leukocytes response to PRRSV infection mainly involves CD8+ T cells. (usda.gov)
Dissemination of pathogens from a primary site of colonization or infection can occur via different routes, including lymphatic vessels and the blood stream ( 1 ). (frontiersin.org)
Therefore, we previously established an ex vivo human whole-blood infection model that allowed us to define which immune cells interact with the human fungal pathogen Candida albicans ( 4 ), to identify cross-talk between different components of the host response ( 5 ), and to detect substantial differences between related fungal pathogens ( 6 ). (frontiersin.org)
We used blot hybridization with a cloned subgenomic probe to quantitate viral DNA in blood leukocytes of 60 viremic patients (25 with solid organ transplants, 20 with AIDS, and 15 marrow recipients) who had different clinical manifestations of CMV infection. (jci.org)
Enhanced apoptosis in the leukocytes of peripheral blood of PEM patients may be a marker of increased infection and immune disturbances. (who.int)
There were 18 non-oedematous infants (8 described in peripheral blood and lymphatic males and 10 females) with mean age 10.78 organs during infection [ 9 ]. (who.int)

Dermatophatologists observe mononuclear leukocytes in close apposition to keratinocytes (KCs) in graft versus host disease and in other lymphocyte-mediated skin diseases, such as lichen planus, erythema multiforme, and lupus erythematosus. (elsevierpure.com)
SIV appears to be primarily tropic for CD4 (T4)-positive leukocytes and has not been successfully propagated in B-lymphocyte cell lines (e.g. (cdc.gov)
It thus defines L-selectin as a human lymphocyte homing receptor for peripheral lymph node HEV. (bdbiosciences.com)

In contrast, HLA-G tetramers did bind to peripheral blood monocytes, staining a CD16(+)CD14(mid) subset with greater intensity. (ox.ac.uk)
However, staining in the presence of antibodies reactive with ILT receptors revealed that the interaction of HLA-G tetramers with blood monocytes was largely due to binding to ILT4. (ox.ac.uk)

In human mononuclear leukocytes, beta-AR agonist isoproterenol and platelet-activating factor were able to induce translocation of beta ARK from cytosol to membrane. (unich.it)
The high levels of beta ARK expression in human peripheral blood leukocytes together with the ability of isoproterenol and platelet-activating factor to induce beta ARK translocation, suggest a role for beta ARK in modulating some receptor-mediated immune functions. (unich.it)
For human blood, opsonization was shown to decrease platelet interaction suggesting that complement factors interfere with fungus-to-platelet binding. (frontiersin.org)
Patients with APL may be stratified into the following 3 risk categories on the basis of white blood cell (WBC) count and platelet count. (medscape.com)

A complete blood count (CBC) with differential should be performed. (medscape.com)
In leukemia, hematological parameters especially in the case of leukocyte differential count helps early diagnosis of leukemia. (horiba.com)

Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule. (bdbiosciences.com)

The effect of chemotherapeutic agents - cytosine arabinoside, methotrexate, procarbazine, vinblastine and vincristine - generally applied in the treatment of human cancer were tested on the motility of polymorphonuclear leukocytes. (karger.com)

Replication was attempted using maternal folate intake and blood methylation data from the MoBa study and verified if the findings were significant in a previous EWAS of maternal serum folate in cord blood. (lu.se)
Obesity related methylation changes in DNA of peripheral blood leukocytes. (ironmagazine.com)
Epigenetics in Pregnancy (EPIPREG) - population-based sample of European and South Asian pregnant women with epigenome-wide DNA methylation (850k) in peripheral blood leukocytes (PLoS ONE 16(8): e0256158. (lu.se)

This document describes standard protocols used by the Hutchinson group for analysis of human blood leucocyte populations by flow cytometry (1). (researchsquare.com)

The nonclassical MHC class I molecule human histocompatibility leukocyte antigen (HLA)-G is selectively expressed on fetal trophoblast tissue at the maternal-fetal interface in pregnancy. (ox.ac.uk)

DuraClone reagents are dry pre-formulated antibody panels for extensive phenotyping of T cells, B cells, NK cells, dendritic cells and granulocytes in whole blood. (researchsquare.com)

This study aimed to investigate the expression of CD200 on the surface of peripheral blood leukocytes in patients with alcohol use disorder and compare them with controls. (qxmd.com)
The study indicates that cellular expression of CD200 on the surface of peripheral blood leukocytes is reduced in alcohol-dependent patients. (qxmd.com)
Peripheral blood samples were taken from patients not enduring headache attacks and not undergoing prophylactic treatment. (nih.gov)
A significant reduction in peripheral blood mononuclear cell beta-endorphin concentrations was observed in migraine patients with and without aura, but not in tension-type headache patients. (nih.gov)

DEFINITION: Leukemia is a malignant disease of blood forming organs of the body that results in uncontrolled growth of immature white blood cells. (slideshare.net)
Bone marrow contains stem cells, which are immature cells that become blood cells. (medlineplus.gov)

More mature RBC precursors are destroyed in the bone marrow prior to entering the blood stream (intramedullary hemolysis). (medscape.com)
INTRODUCTION:  Leukemia describes a group of malignant disorders in which uncontrolled proliferation of leucocyte in the bone marrow infiltrate the blood forming tissues of the bone marrow, lymph system, liver and spleen. (slideshare.net)
Also during maintenance therapy, periodic Complete blood screening is done to evaluate the bone marrow's response to the drugs. (slideshare.net)
Acute leukopenia, with almost total absence of granular leukocytes, leukoblastic groups and lymphoid tissue in the bone marrow, was reported in the case of a 36-year-old chemist who had worked with radium for 14 years (Reitter and Martland 1926). (cdc.gov)
Bone marrow donation can be done either by collecting a donor's bone marrow surgically, or by removing stem cells from a donor's blood. (medlineplus.gov)
First, the donor is given 5 days of shots to help stem cells move from the bone marrow into the blood. (medlineplus.gov)

Since the KCs are Class II histocompatibility antigen (HLA-DR) positive in these diseases (indicating local production of gamma interferon, IFN-γ, by activated T-cells), we sought to determine whether IFN-γ treatment of KCs would influence the ability of allogeneic peripheral blood mononuclear leukocytes (PBMLs) to adhere to cultured KCs in vitro. (elsevierpure.com)
Nickoloff, BJ , Lewinsohn, DM & Butcher, EC 1987, ' Enhanced binding of peripheral blood mononuclear leukocytes to γ-interferon-treated cultured keratinocytes ', American Journal of Dermatopathology , vol. 9, no. 5, pp. 413-418. (elsevierpure.com)

This document describes standard protocols used by the Hutchinson group for profiling human peripheral blood leucocytes by flow cytometry analyses using DuraClone IM reagents. (researchsquare.com)
A panel of monoclonal antibodies was used to analyze peripheral blood leukocytes by two-color flow cytometric analysis. (usda.gov)
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. (biolegend.com)

We also detected changes in energy utilization and immune responses in leukocytes from older cows. (biomedcentral.com)
However, our understanding of how pathogens interact with cellular and humoral host factors in blood is limited, mainly due to technical issues: While it is relatively easy to study the interaction of pathogens with isolated blood cells, or their survival in serum or plasma, such approaches lack the complexity of interactions between different types of immune cells and additional factors, e.g., complement, present in blood. (frontiersin.org)

Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells. (ox.ac.uk)
NK cells were obtained from peripheral blood (PB) of healthy volunteers. (springer.com)
Megaloblasts are large nucleated red blood cells. (medscape.com)
Megaloblastic changes are most apparent in rapidly dividing cells such as blood cells and gastrointestinal cells. (medscape.com)
We hypothesized that this poor response is associated with a reduced effect of corticosteroids to inhibit cytokine release from activated peripheral blood mononuclear cells (PBMCs). (nih.gov)
Levels of beta-endorphin in peripheral blood mononuclear cells have been studied as a new approach to investigating opioid tone in migraine and tension-type headache. (nih.gov)
Altered transmitter modulation to peripheral blood mononuclear cells may be the cause of this alteration, which could be part of a more diffuse opioid system derangement in migraine subjects. (nih.gov)
It also plays a role in leukocyte rolling on activated endothelial cells. (biolegend.com)
The cells or blood is then tested for special proteins, called human leukocytes antigens (HLAs). (medlineplus.gov)
The part of white blood cells that contains stem cells is then separated in a machine and removed to be later given to the recipient. (medlineplus.gov)
The red blood cells are returned to the donor through an IV in the other arm. (medlineplus.gov)

Leucocyte typing V : white cell differentiation antigens : proceedings of the fifth international workshop and conference held in Boston, USA, 3-7 November, 1993. (bdbiosciences.com)

Aim: To perform an epigenome-wide association study (EWAS) of serum folate in maternal blood. (lu.se)
Rotating-shift nurses after a day off: peripheral clock gene expression, urinary melatonin, and serum 17-estradiol levels. (sjweh.fi)

The results are expressed as pg of viral DNA/10 micrograms of leukocyte DNA. (jci.org)

In marrow recipients, the severity of CMV disease, even when fatal, is not reflected quantitatively in peripheral blood leukocytes. (jci.org)

Floor heating system regulated total number of peripheral leukocyte. (scirp.org)
The cellular expression of CD200 on total leukocytes (median ± IQR) [39.94 (28.85, 50.01)] in cases was significantly lower compared to controls [45.07 (37.70, 51.69)] (U = 896, p = 0.015). (qxmd.com)
The total leukocyte count varies. (medscape.com)

Oncolytic vesicular stomatitis virus (VSV) can be delivered intravenously to target primary and metastatic lesions, but the interaction between human peripheral blood leukocytes (PBLs) and VSV remains poorly understood. (karger.com)

Over the course of two weeks, twenty-two participants completed subjective (Acute Subjective Effects of Nicotine) and physiological (blood pressure, heart rate, and CO level) measures. (who.int)

Jones AL, van der Woord M, Bourrillon F. Use of a whole blood competitive immunoassay for the assessment of worker exposed to propylene oxide at three manufacturing facilities. (who.int)

Our results reveal substantial differences between murine and human whole-blood models infected with C. albicans and thereby demonstrate limitations in the translatability of this ex vivo model between hosts. (frontiersin.org)

Decreased expression of CD200 on peripheral blood leukocytes in alcohol dependence. (qxmd.com)
High expression of beta-adrenergic receptor kinase in human peripheral blood leukocytes. (unich.it)

Peripheral blood samples were collected at baseline and at follow up. (cdc.gov)

Very high levels of beta ARK mRNA and kinase activity were found in peripheral blood leukocytes and in several myeloid and lymphoid leukemia cell lines. (unich.it)
Peripheral blood stem cell collection. (medlineplus.gov)

The findings were not replicated and were not significant in cord blood. (lu.se)
No significant changes were found in peripheral blood leukocytes of pigs inoculated with attenuated PRRSV or sham inoculum. (usda.gov)

A 2-mL venous blood sample was collected from cases and controls for immunophenotyping of CD200. (qxmd.com)

Whole-blood models can help to elucidate host-pathogens interactions and have been used for several Candida species in human blood. (frontiersin.org)

Unlike human blood, murine blood was unable to reduce fungal burden and more substantial filamentation of C. albicans was observed. (frontiersin.org)

In mice, as the most commonly used laboratory animal for in vivo experiments, the blood volume that can be withdrawn repeatedly is very limited and thereby hampers in depth analysis of interactions within blood. (frontiersin.org)

Anatomy8

Organisms1

Diseases2

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Psychiatry and Psychology1

Phenomena and Processes6

Information Science1

Health Care2

Mitochondrial DNA content1

Smear8

Subsets3

Smears3

Lymphocytes6

Neutrophils2

Counts4

Platelets3

Infection8

Lymphocyte3

Monocytes2

Platelet4

Differential2

Lymph node1

Polymorphonuclear1

Methylation3

Populations1

Fetal1

Dendritic cells1

Patients4

Immature2

Bone6

Mononuclear Leukocytes2

Flow3

Immune2

Cells11

Differentiation1

Serum2

Viral1

Disease1

Total3

Interaction1

Acute1

Assessment1

Results1

Expression2

Samples1

Cell2

Significant2

Venous1

Species1

Human blood1

Mice1