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  • angiogenesis
  • BL-8040 is a short peptide that functions as a high-affinity antagonist for CXCR4, a chemokine receptor that is directly involved in tumor progression, angiogenesis (growth of new blood vessels in the tumor), metastasis (spread of the disease to other organs or organ parts) and cell survival. (technologynetworks.com)
  • Thus
  • Thus, p38 appears to play a critical role in the pathogenesis of aplastic anemia, suggesting that selective pharmacological inhibitors of this kinase may prove useful in the treatment of aplastic anemia and other cytokine-mediated bone marrow failure syndromes. (jimmunol.org)
  • samples
  • Cancer-testis antigens (CTAs) as a novel group of tumor-associated antigens have been demonstrated to be expressed in HCC samples as well as peripheral blood samples from these patients but not in the corresponding adjacent noncancerous samples. (readbyqxmd.com)
  • Results from samples taken from bone marrow were 10 times more than peripheral blood ones, but with relevant individual variations. (vin.com)
  • All donations of blood samples were obtained with informed consent according to the criteria established by the Institutional Review Board at the Hokkaido Red Cross Blood Center. (bloodjournal.org)
  • Blood, bone marrow, and buccal mucosa samples will be assigned a unique product number and the study investigators listed on this protocol will serve as the custodians of the code that links the product with a donor s identity. (clinicaltrials.gov)
  • hematopoiesis
  • Peripheral blood in semisolid media achieves the study of the hematopoiesis and its pathology, moreover it gives a very relevant experimental model to evaluate blood-toxicity phenomenon. (vin.com)