• By inflating during ventricular diastole and deflating during systole, IABP enhances coronary artery perfusion and increases cardiac output. (nursingbird.com)
  • Increased perfusion pressure and lower left ventricular volume - related intramyocardial resistance are likely responsible for the Impella - induced increase in coronary flow. (nursingbird.com)
  • The aim of this study is to examine the effect of rh-EPO in a pig model of ventricular fibrillation (VF)-induced CA. (nih.gov)
  • Ventricular fibrillation was electrically induced in 20 piglets and maintained untreated for 8 minutes before attempting resuscitation. (nih.gov)
  • Most survivors of adult cardiac arrest have an initial rhythm of ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT), and these patients are best treated initially with chest compressions and early defibrillation rather than airway management. (medscape.com)
  • Technical Recommendations for Computed Tomography Guidance of Intervention in the Right Ventricular Outflow Tract: Native RVOT, Conduits and Bioprosthetic Valves: A White Paper of the Society of Cardiovascular Computed Tomography (SCCT), Congenital Heart Surgeons' Society (CHSS), and Society for Cardiovascular Angiography & Interventions (SCAI). (ottawaheart.ca)
  • This hypothesis will be addressed in dogs subjected to ventricular fibrillation cardiac arrest, CPR, defibrillatory countershocks and recovery. (unthsc.edu)
  • 1 Cardiac arrest itself in the catheterisation laboratory (cath lab) is not an uncommon event, but is usually rapidly resolved with cardiopulmonary resuscitation (CPR) and DC conversions in cases of ventricular fibrillation, especially following reperfusion in patients with acute myocardial infarction during primary percutaneous intervention (PCI). (icrjournal.com)
  • Methods: In a closed chest porcine model, cardiac arrest was established through electrically induced ventricular fibrillation (VF) in eleven pigs. (lu.se)
  • After surgical preparation, 15 minutes of untreated ventricular fibrillation was induced. (ceemjournal.org)
  • The mechanical impact can induce ventricular fibrillation , even if the force seems relatively minor. (ecgwaves.com)
  • After heart transplantation, the donor heart preservation with normoxic CM was associated with shorter re-beating time, histopathological scores, and left ventricular systolic diameter, higher ejection fraction, and fractional shortening of transplanted hearts. (researchsquare.com)
  • Short-term cardiac stress, induced by ischemia-reperfusion (I/R) injury resulted in impaired left ventricular (LV) recovery and increased infarct size in heterozygous Hmox1-deficient (Hmox1 +/− ) mice [ 55 ]. (springer.com)
  • A simplified technique for reversed cerebral perfusion during hypothermic circulatory arrest for transverse aortic arch repair is described. (nih.gov)
  • Deep hypothermic circulatory arrest (DHCA) is a surgical technique in which the temperature of the body falls significantly (between 20 °C (68 °F) to 25 °C (77 °F))and blood circulation is stopped for up to one hour. (wikipedia.org)
  • Cardiopulmonary bypass machines were essential to the development of deep hypothermic circulatory arrest (DHCA) in humans. (wikipedia.org)
  • Increasingly complex repairs subsequently became possible with the refinement of cardiopulmonary bypass (CPB) techniques and the use of hypothermic circulatory arrest that Barratt-Boyes et al (1971) and Castaneda et al (1974) popularized. (medscape.com)
  • Deep Hypothermic Circulatory Arrest (DHCS) is a technique used mainly to facilitate complex aortic arch surgery. (wfsahq.org)
  • Deep Hypothermic Circulatory Arrest (DHCA) is a technique employed to facilitate complex cardiovascular surgery. (wfsahq.org)
  • The use of hypothermic circulatory arrest is limited by the duration of the circulatory arrest that can safely be tolerated before significant neurological and multisystem side effects occur. (wfsahq.org)
  • After birth, increased oxygen requirements of the myocardium are associated with a switch from a relatively anaerobic metabolism in an immature heart to a more aerobic metabolism. (medscape.com)
  • These solutions induce a hyperpolarizing arrest of the myocardium which decreases energy consumption and intracellular accumulation of Ca 2+ . (ccasociety.org)
  • There is an increased incidence of brain injury at times longer than 40 minutes, but sometimes circulatory arrest for up to 60 minutes is used if life-saving surgery requires it. (wikipedia.org)
  • In this procedure, the first successful open heart surgery, Lewis repaired an atrial septal defect in a 5-year-old girl during 5 minutes of total circulatory arrest at 28 °C. Many similar procedures were performed by Soviet heart surgeon, Eugene Meshalkin, in Novosibirsk during the 1960s. (wikipedia.org)
  • Thereafter, the only surgeries that required stopping blood circulation to the whole body ("total circulatory arrest") were surgeries involving blood supply to the brain. (wikipedia.org)
  • The only heart surgeries that continued to require total circulatory arrest were repairs to the aortic arch. (wikipedia.org)
  • By 1959, it was known from the animal experiments of Bigelow, Andjus and Smith, Gollan, Lewis's colleague, Niazi, and others that temperatures near 0 °C could be survived by mammals, and that colder temperature permitted the brain to survive longer circulatory arrest times, even beyond one hour. (wikipedia.org)
  • Humans had survived cooling to 9 °C, and circulatory arrest of 45 minutes, using external cooling only. (wikipedia.org)
  • This can begin circulatory arrest before the brain has reached a safe temperature. (wikipedia.org)
  • Mechanical circulatory support allows users to minimize heart effort while maintaining essential organ perfusion without the risk of vasopressor side effects (Emory Department of Medicine, 2017). (nursingbird.com)
  • Deep hypothermia reduces cellular metabolism and protects tissues from ischaemia during circulatory arrest, most importantly the central nervous system. (wfsahq.org)
  • Conversely, VV-ECMO provides primarily respiratory support, offloading the responsibility of oxygenation from the lungs, while still relying on the heart for circulatory function, and is not commonly used in PE treatment. (emra.org)
  • Pyruvate or control NaCl will be infused intravenously during CPR and the first 55 min recovery, or in a delayed manner 120-180 min after restoration of cardiac rhythm and brain perfusion. (unthsc.edu)
  • Visual assessment of brain perfusion MRI scans in dementia: a pilot study. (lu.se)
  • The first heart surgery using hypothermia to provide a longer time that blood circulation through the whole body could be safely stopped was performed by F. John Lewis and Mansur Taufic at the University of Minnesota in 1952. (wikipedia.org)
  • This is a multicenter trial to establish the efficacy of cooling and the optimal duration of induced hypothermia for neuroprotection in pediatric comatose survivors of cardiac arrest. (nih.gov)
  • In addition to the usual complications of cardiac surgery and cardiopulmonary bypass, deep hypothermia induces a significant coagulopathy. (wfsahq.org)
  • the rare exception is profound hypothermia caused by cold water immersion, when successful resuscitation may be accomplished even after prolonged arrest (up to 60 minutes). (msdmanuals.com)
  • Crucial information on pyruvate's neuroprotective mechanisms and its ability to induce erythropoietin signaling within the brain will provide the essential foundation for eventual clinical exploitation of this cerebroprotective phenomenon. (unthsc.edu)
  • The ability to induce cardiac arrest and facilitate open-heart surgery by infusing a high potassium-containing solution into the coronaries was first demonstrated by Melrose et al. (ccasociety.org)
  • The hemodynamic advantages are thought to exceed the dangers of an inotropic treatment since hypotension impairs myocardial perfusion (Mandawat, 2017). (nursingbird.com)
  • Hyperventilation-induced hypotension during cardiopulmonary resuscitation. (aaukr.org)
  • Massive pulmonary emboli (PE) -- which are pulmonary emboli that induce sustained hypotension, pulselessness, or sustained bradycardia -- are incredibly deadly, even with intervention. (emra.org)
  • The purpose of post-arrest cardiogenic shock therapy is to reduce cardiac effort while keeping essential organs perfused. (nursingbird.com)
  • Increasing vasopressors is associated with poor clinical outcomes in cardiogenic shock induced by acute myocardial infarction. (nursingbird.com)
  • In those with cardiac arrest or cardiogenic shock, it appears to improve survival and good outcomes. (wikipedia.org)
  • Cardiogenic shock may be prevented with early revascularization in patients with myocardial infarction (MI) and with required intervention in patients with structural heart disease. (medscape.com)
  • Since heart-lung machines, also known as cardiopulmonary bypass (CPB), had not been invented yet, stopping the heart meant stopping blood circulation to the whole body, including the brain. (wikipedia.org)
  • The advent of cardiopulmonary bypass in the United States during the 1950s allowed the heart to be stopped for surgery without having to stop circulation to the rest of the body. (wikipedia.org)
  • Cardiopulmonary bypass machines allow blood circulation and cooling to continue below the temperature at which the heart stops working. (wikipedia.org)
  • By cooling blood directly, cardiopulmonary bypass also cools people faster than surface cooling, even if the heart is not functioning. (wikipedia.org)
  • Cardiopulmonary bypass was established using median sternotomy with systemic perfusion from ascending aortic and bicaval drainage. (biomedcentral.com)
  • The technology for ECMO is largely derived from cardiopulmonary bypass , which provides shorter-term support with arrested native circulation. (wikipedia.org)
  • Generally, it is used either post-cardiopulmonary bypass or in late-stage treatment of a person with profound heart and/or lung failure, although it is now seeing use as a treatment for cardiac arrest in certain centers, allowing treatment of the underlying cause of arrest while circulation and oxygenation are supported. (wikipedia.org)
  • Later, antegrade and retrograde cardioplegia induced cardiac arrest. (biomedcentral.com)
  • In post-arrest individuals, particularly those with obstructive coronary artery disease, these hemodynamic consequences may be significant. (nursingbird.com)
  • In the United States alone, over 14 million persons suffer from some form of coronary artery disease (CAD) or its complications, including congestive heart failure (CHF), angina, and arrhythmias. (medscape.com)
  • When the recurrent use of atropine is essential in patients with coronary artery disease, the total dose should be restricted to 2 to 3 mg (maximum 0.03 to 0.04 mg/kg) to avoid the detrimental effects of atropine-induced tachycardia on myocardial oxygen demand. (nih.gov)
  • This study will use dual energy x-ray computed tomography (DECT) to evaluate the relationship between heterogeneous perfusion, hypoxia (low oxygen in inspired gas) and induction of pulmonary vascular dilatation to characterize emphysema susceptibility in a normal smoking population. (nih.gov)
  • Hypoxia is common in traumatic cardiac arrest and can arise from a range of injuries. (ecgwaves.com)
  • Global brain hypoxia-ischemia during cardiac arrest has a long-term impact on processing and transfer of sensory information by thalamic circuitry. (cdc.gov)
  • Normally when the heart stops beating, organs begin to swell, collapsing blood vessels and blocking circulation, he said. (yale.edu)
  • In brief, VA-ECMO provides both hemodynamic and respiratory support by offloading the responsibility for circulation from heart and oxygenation by the lungs. (emra.org)
  • 3-6 During the course of a lengthy resuscitation effort due to cardiac arrest in the cath lab, quick restoration of circulation through advanced cardiac life support is required and is almost universally immediately started with manual chest compressions delivered on the cath lab table. (icrjournal.com)
  • Often the cause of the extended cardiac arrest can easily be identified and a continued uninterrupted PCI procedure of, for example, a suddenly occluded left main artery is often the best option for attaining return of spontaneous circulation (ROSC). (icrjournal.com)
  • Background: Mechanical chest compressions (CCs) have been shown capable of maintaining circulation in humans suffering cardiac arrest for extensive periods of time. (lu.se)
  • Only indirect measurements of the coronary circulation during cardiac arrest with on-going mechanical CCs have been performed previously through measurement of the coronary perfusion pressure (CPP). (lu.se)
  • 5. True Perfusion is the circulation of blood through tissues. (antiessays.com)
  • Aniline induces methemoglobinemia, which impairs the delivery of oxygen to tissues. (cdc.gov)
  • Within two minutes without blood flow (due to heart stoppage or blood vessel occlusion) neurons lack the energy to power the sodium/potassium pump. (benbest.com)
  • The first was whether reticulospinal neurons induce monosynaptic EPSPs in contralateral lumbar motoneurons. (jneurosci.org)
  • We used single neuron recordings and controlled whisker deflections to examine responses of thalamocortical neurons to sensory stimulation in rat survivors of 9 min of asphyxial cardiac arrest incurred on post-natal day 17. (cdc.gov)
  • We found that 48-72 hours after cardiac arrest, thalamocortical neurons demonstrate significantly elevated firing rates both during spontaneous activity and in response to whisker deflections. (cdc.gov)
  • How do you protect cells and organs from the harmful effects of oxygen deprivation and reintroduction, follwing a stroke, heart attack or respiratory arrest? (lemonde.fr)
  • Teams from the Yale School of Medicine (Connecticut, USA) described a perfusion system called OrganEx, that allowed oxygen to be recirculated throughout the body of a pig. (lemonde.fr)
  • Diastolic aortic pressure and coronary perfusion pressure during cardiopulmonary resuscitation were significantly higher in the EPO group compared with the control group. (nih.gov)
  • Moreover, intravenous pyruvate infusion during cardiopulmonary resuscitation (CPR) prevented subsequent neurological impairment and neuronal apoptosis 3 days after cardiac arrest. (unthsc.edu)
  • Erythropoietin mRNA and protein content, signaling kinase activation, neutrophil infiltration, and activities of proapoptotic caspases, pro-inflammatory matrix metalloproteinases, and the cytoprotective enzyme endothelial nitric oxide synthase will be measured in vulnerable brain regions biopsied at 5 h, 2 d and 4 d after cardiac arrest-resuscitation. (unthsc.edu)
  • Серцево-легенева реанімація (СЛР) у немовлят та дітей Despite the use of cardiopulmonary resuscitation (CPR), mortality rates for out-of-hospital cardiac arrest are about 90% for infants and children. (msdmanuals.com)
  • Head elevation at an angle of 30° during cardiopulmonary resuscitation (CPR) was hemodynamically beneficial compared to supine position in a previous porcine cardiac arrest experimental study. (ceemjournal.org)
  • If trauma is not definitively established as the cause of cardiac arrest, cardiopulmonary resuscitation ( CPR ) should be performed per standard guidelines. (ecgwaves.com)
  • If treated with cardiopulmonary resuscitation, however, cardiac arrest is survivable, but survivors often show evidence of injury in selectively vulnerable regions of the brain. (cdc.gov)
  • Administration of rh-EPO in a pig model of VF-induced CA just before reperfusion facilitates ROSC and improves survival rates as well as hemodynamic variables. (nih.gov)
  • Yet, clinical outcomes have remained poor, with a pooled global 30-day survival rate for out-of-hospital cardiac arrest (OHCA) patients of 10.7% [ 6 ]. (jemsmed.org)
  • To review the literature which has previously reported on survival and the predictors of mortality in patients with massive PE in cardiac arrest who received VA-ECMO. (emra.org)
  • 2 A smaller number of patients will suffer an extended period of cardiac arrest, however, and survival among these patients is very low with more or less only anecdotal reports of survival among patients, usually suffering from a lesion in the left main artery or the left anterior descending artery. (icrjournal.com)
  • This study aimed to assess the effect of head-up tilt position during CPR on 24-hour survival in a porcine cardiac arrest experimental model. (ceemjournal.org)
  • Cardiac arrests due to trauma are characterized by very low survival rates. (ecgwaves.com)
  • In heart transplantation, donor hearts inevitably suffer from ischemia/reperfusion (I/R) injury, which leads to primary graft dysfunction and affects patients' survival rate. (researchsquare.com)
  • Therefore, attenuating myocardial I/R injury during the heart transplant procedure would have a favorable impact on improving short- and long-term graft function and recipient's survival(6). (researchsquare.com)
  • An IABP may be placed in the emergency department (ED) as a bridge to percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), to decrease myocardial workload, and to improve end-organ perfusion. (medscape.com)
  • An in-depth analysis of the animals' brain, heart, lung, liver, kidney and pancreatic tissues also revealed less cellular destruction and more signs of cellular repair, after OrganEx perfusion. (lemonde.fr)
  • Illustration of organ perfusion and cellular recovery with OrganEx technology. (yale.edu)
  • The technology consists of a perfusion device similar to heart-lung machines - which do the work of the heart and lungs during surgery - and an experimental fluid containing compounds that can promote cellular health and suppress inflammation throughout the pig's body. (yale.edu)
  • Six hours after treatment with OrganEx, the scientists found that certain key cellular functions were active in many areas of the pigs' bodies - including in the heart, liver, and kidneys - and that some organ function had been restored. (yale.edu)
  • Depressed Ca2+ activation of contraction as a consequence of reperfusion-induced cellular calcium overload in ferret hearts. (google.ca)
  • It might also be able to help treat organs or tissue damaged by ischemia during heart attacks or strokes. (yale.edu)
  • Ischemia and reperfusion can cause serious brain damage in stroke or cardiac arrest. (benbest.com)
  • DESCRIPTION (provided by applicant): The leading cause of death in the United States, cardiac arrest imposes profound ischemia on the brain and other internal organs. (unthsc.edu)
  • Cardioplegic solutions cause diastolic arrest, decrease cardiac metabolic demand, and improve myocardial tolerance to ischemia. (ccasociety.org)
  • [ 1 ] Gibbon first described and used a mechanical extracorporeal oxygenator, which he termed the heart-lung machine. (medscape.com)
  • Зупинка серця Cardiac arrest is the cessation of cardiac mechanical activity resulting in the absence of circulating blood flow. (msdmanuals.com)
  • Conclusion: Our study showed good correlation between CPP and APV which was highly significant, during cardiac arrest with on-going mechanical CCs in a closed chest porcine model. (lu.se)
  • Mechanical CCs can, at minimum, re-establish coronary blood flow in non-diseased coronary arteries during cardiac arrest. (lu.se)
  • In this report, we describe dynamic changes in regionally prevailing cardiomyocyte (fibre) and myolaminar (sheet) orientations, using Diffusion Tensor Imaging (DTI) of ventricles in the same living heart in two different mechanical states. (ox.ac.uk)
  • ECMO, in fact, did not allow proper perfusion of all organs, as many small blood vessels collapsed. (lemonde.fr)
  • Complete cardiopulmonary arrest is induced to allow surgery on major blood vessels which cannot be bypassed intraoperatively and therefore upon which surgery would normally cause disruption to distal blood flow and profound haemorrhage in the surgical field. (wfsahq.org)
  • Which cardioplegia solution produces a hyperpolarized cardiac arrest? (ccasociety.org)
  • Cryonics patients frequently experience ischemic & reperfusion injury between the time when the heart stops and cryostorage begins. (benbest.com)
  • In this article I attempt to evaluate the nature & extent of ischemic & reperfusion injury -- primarily focused on the impact for cryonics (although certainly relevant to stroke and cardiac arrest). (benbest.com)
  • The cAMP analogue 8-Br-cAMP-AM (8-Br) confers marked protection against global ischaemia/reperfusion of isolated perfused heart. (mdpi.com)
  • The result: "After six hours of perfusion, OrganEx did much better than ECMO in terms of getting fluids flowing again in arteries and organs," Mr. Parent summarized. (lemonde.fr)
  • Extracorporeal membrane oxygenation ( ECMO ), also known as extracorporeal life support ( ECLS ), is an extracorporeal technique of providing prolonged cardiac and respiratory support to persons whose heart and lungs are unable to provide an adequate amount of gas exchange or perfusion to sustain life. (wikipedia.org)
  • Even when cardiac rhythm is restored, most cardiac arrest victims eventually succumb to the devastating effects of irreversible brain damage, and many survivors suffer persistent, debilitating neurological impairment. (unthsc.edu)
  • Nonetheless, prompt interventions can reverse cardiac arrest and survivors of traumatic cardiac arrest often exhibit favorable neurological outcomes ( Rawshani et al ). (ecgwaves.com)
  • This comprehensive and well-designed study has the potential to lead to new treatment strategies for people who have a heart attack or stroke" explained Mr. Porte. (lemonde.fr)
  • Excessive glutamate release resulting in excessive Ca +2 entry into cells is the excitotoxicity which initiates the brain ischemic damage seen in stroke and cardiac arrest. (benbest.com)
  • For purposes of brevity, this discussion will focus on adult patients with acute cardiac conditions (cardiac arrest and dysrhythmias), excluding acute coronary syndromes, stroke, and pediatric considerations. (medscape.com)
  • Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate. (google.ca)
  • Maybe try split brain experiments, or stroke induced personality disorders. (abovetopsecret.com)
  • In the first group (control), myocardial anoxia was induced in normothermia and no cardioplegic solution was administered. (rbccv.org.br)
  • Donor hearts were explanted, stored in cardioplegic solution supplemented with either a medium (Vehicle), normoxic CM (N-CM), or hypoxic CM (H-CM), and then heterotopically transplanted. (researchsquare.com)
  • Our results indicate that cardioplegic solution-enriched with hypoxic CM-BMSCs can be a novel and promising preservation solution for donor hearts. (researchsquare.com)
  • [ 3 , 4 ] Further refinements in CPB hardware and techniques, perfusion methods, myocardial and brain protection over the past seven decades contributed to improved outcomes of surgical treatment of CHD. (medscape.com)
  • Pharmacological neuroprotection and adjuvant perfusion methods are often used to improve the safety of the technique. (wfsahq.org)
  • However, because erythropoietin cannot readily traverse the blood-brain barrier, massive dosages are required to achieve significant neuroprotection, and outcomes of recent clinical trials of intravenous erythropoietin in cardiac arrest victims have been disappointing. (unthsc.edu)
  • The American Heart Association (AHA) developed the first CPR guidelines in 1966 and since that time has published frequent updates of the guidelines to help educate the public and medical establishment about optimal care for patients with cardiac arrest and other emergency cardiovascular conditions. (medscape.com)
  • Part I is a summary statement of the major changes in cardiac arrest and emergency cardiovascular care since the previous set of guidelines, which were published in 2005. (medscape.com)
  • the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), and the National Heart, Lung and Blood Institute (NHLBI) have recognized the wide variation in awareness and understanding of the role of cardiac rehabilitation among physicians, ancillary health care providers, third-party payers, and patients with heart disease. (medscape.com)
  • See also the American Heart Association [AHA] 2020 guidelines for CPR and emergency cardiovascular care and 2022 AHA Interim Guidance to Health Care Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19. (msdmanuals.com)
  • Phosphine is a respiratory tract irritant that attacks primarily the cardiovascular and respiratory systems causing peripheral vascular collapse, cardiac arrest and failure, and pulmonary edema. (cdc.gov)
  • Hearts, isolated from Sprague-Dawley rats, were Langendorff-perfused and imaged, initially in their slack state during cardioplegic arrest, then during lithium-induced contracture. (ox.ac.uk)
  • To test their system, they induced cardiac arrest in pigs. (lemonde.fr)
  • Cardiac arrest was induced in anesthetized pigs, which were treated with OrganEx an hour after death. (yale.edu)
  • Currently, complete repair of congenital heart defects can be performed in infants smaller than 2 kg, with good outcomes. (medscape.com)
  • This procedure is thought to improve clinical outcomes in cardiac arrest. (jemsmed.org)
  • Preoperative evaluation of all patients concerning medical history, clinical examination including ECG and chest x-ray, complete laboratory investigations and Echo Doppler evaluation of the heart and valves, coronary angiography were done. (ispub.com)
  • In cases of traumatic cardiac arrest , addressing reversible etiologies takes precedence over chest compressions. (ecgwaves.com)
  • Traumatic cardiac arrests typically result from mechanisms that render chest compressions ineffective. (ecgwaves.com)
  • Consequently, addressing reversible causes of cardiac arrest becomes more critical than performing chest compressions. (ecgwaves.com)
  • While commotio cordis is caused by trauma to the chest, it is managed as a non-traumatic cardiac arrest (i.e. standard CPR , as per guidelines). (ecgwaves.com)
  • To show enlargement of the right side of the heart an echocardiogram, CT scan, or MRI of the chest may be used. (antiessays.com)
  • A chest x-ray can show if the heart is enlarged, there is fluid in the lungs, or lung disease. (antiessays.com)
  • This was accompanied by higher numbers of Ly6C hi monocytes in peripheral blood, as well as higher expression of monocyte chemoattractant protein-1 and adhesion molecules in the hearts of MI-operated Hmox1 −/− mice. (springer.com)
  • The incidence of congenital heart disease (CHD) is 2-10 cases per 1000 live births. (medscape.com)
  • Altered hemodynamics in neonates, especially in relation to prematurity, congenital heart disease, and central nervous system injury. (stanford.edu)
  • Heart attack and death have occurred in patients who received Lexiscan (regadenoson) or Adenoscan (adenosine) for a cardiac nuclear stress test. (fda.gov)
  • The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. (nih.gov)
  • Although approximately 2,000,000 patients undergo PCI yearly worldwide, only a very small minority will suffer a protracted cardiac arrest episode during the procedure that results in death. (icrjournal.com)
  • Cardiac arrest stops blood from flowing to vital organs, depriving them of. (msdmanuals.com)
  • However, the term sinus node arrest is only used if none of the heart's pacemaker centers generate any excitation and thus a pause, or asystole, prevails. (ecgbuddy.com)
  • The results from the breakthrough study, which involved the use of an innovative perfusion system, could prove to be particularly useful for emergency treatment of strokes and heart attacks and for facilitating organ transplants. (lemonde.fr)
  • [ 2 ] On May 6, 1953, Gibbon performed the first successful open heart surgery using a heart-lung machine while repairing an atrial septal defect. (medscape.com)
  • Heart and Lung. (lu.se)
  • Pre-operative assessment and pre-medication are conducted as per any open-heart procedure. (wfsahq.org)