AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth Care
Foramen Ovale, PatentHeart Septal Defects, AtrialEmbolism, ParadoxicalSeptal Occluder DeviceForamen OvaleMigraine DisordersEchocardiography, TransesophagealMigraine with AuraCardiac CatheterizationBalloon OcclusionAtrial SeptumHeart AneurysmPatents as TopicEmbolismValsalva ManeuverPlasmodium ovaleProstheses and ImplantsHeart SeptumMigraine without AuraIntracranial EmbolismStrokeHeart Septal DefectsEchocardiographyCardiac Surgical ProceduresForamen MagnumDecompression SicknessUltrasonography, Doppler, TranscranialTreatment OutcomeIschemic Attack, TransientFluoroscopySecondary PreventionHigh Pressure Neurological SyndromeProsthesis ImplantationHeart Septal Defects, VentricularDivingEmbolism, AirDuctus Arteriosus, PatentFollow-Up StudiesRecurrencePulmonary EmbolismHeart AtriaRadiography, InterventionalProsthesis DesignEchocardiography, Three-DimensionalAnticoagulantsContrast MediaProspective StudiesIntracranial Embolism and ThrombosisEchocardiography, Doppler, ColorEquipment DesignCerebrovascular DisordersThromboembolismCardiovascular Surgical ProceduresHemostatic TechniquesRetrospective StudiesDevice RemovalCarcinoid Heart DiseaseCatheterizationVena Cava, InferiorEmbolectomyCardiac TamponadeBrain IschemiaPuncturesRespiratory ParalysisTherapeutic OcclusionUltrasonography, InterventionalAnoxiaForeign-Body MigrationRisk FactorsHeart DiseasesTime FactorsThrombosisHeart ValvesEquipment SafetyDyspneaHeart InjuriesEchoencephalographyGelatinPostoperative ComplicationsAtrial AppendageFeasibility StudiesAbsorbable ImplantsMagnetic Resonance ImagingPrevalencePostureIntention to Treat AnalysisCerebral InfarctionCerebral Arteries
Association of patent foramCryptogenic strokeTranscatheter closureStrokeMitral valve stFetal circulationRight atrialOrthodeoxiaInteratrialCongenitalOutcomesNaturally after birthHypoxemiaSystemicPatientsIncidenceCardiacUnderwentPulmonaryThrombusDevice closureOccurReductionDiseaseDependDecadesInfantTreatmentBirthHeartCommonShownYearsPotentialPeopleMedicalPopulationPatientRemainsRESPECTEffectiveGenerally
Association of patent foram1
Cryptogenic stroke4
  • However, recently the presence of PFO has been associated with a range of clinical conditions such as cryptogenic stroke, migraine, platypnea- orthodeoxia syndrome, and decompression illness. (unizar.es)
  • There has been heated debate about the role of percutaneous closure of PFO in patients with cryptogenic stroke. (unizar.es)
  • Percutaneous closure of PFO, a minimally invasive procedure to close the PFO using a device can help patients with cryptogenic stroke to reduce the risk of recurrent stroke. (heartvascularcentre.com)
  • Closure of patent foramen ovale versus medical therapy after cryptogenic stroke. (pfostroke.com)
Transcatheter closure2
  • Impact of transcatheter closure of patent foramen ovale in the evolution of migraine and role of residual shunt. (unito.it)
  • The Amplatzer™ Talisman™ PFO Occluder is indicated for percutaneous transcatheter closure of a patent foramen ovale (PFO) to reduce the risk of recurrent ischemic stroke in patients, predominantly between the ages of 18 and 60 years, who have had a stroke due to a presumed paradoxical embolism, as determined by a neurologist and cardiologist following an evaluation to exclude other causes of ischemic stroke. (pfostroke.com)
Stroke6
  • Some patients with clinical conditions including stroke and chronic migraine may benefit from PFO closure. (salesandmarketingnetwork.com)
  • Patent foramen ovale has been linked with paradoxical embolic stroke, platypnea-orthodeoxia syndrome, decompression illness, exacerbation of obstructive sleep apnea, obesity hypoventilation syndrome, chronic pulmonary disease, and migraine headache with aura. (allenpress.com)
  • None of these demonstrated that percutaneous closure was associated with a decreased incidence of stroke compared to medical treatment with antiplatelet agents or anticoagulants. (unizar.es)
  • In this review, were analyzed the pathophysiological mechanisms involved in idiopathic stroke and patent foramen ovale, the diagnostic methods, the benefits published of percutaneous closure, and the treatment indications established in the risk groups, in order to prevent ischemic stroke associated with this congenital heart defect. (unizar.es)
  • The landmark RESPECT trial is the largest trial with the most extensive patient follow-up of any trial conducted on PFO closure to reduce the risk of recurrent ischemic stroke. (pfostroke.com)
  • Long-term outcomes of patent foramen ovale closure or medical therapy after stroke. (pfostroke.com)
Mitral valve st1
  • Persistent left atrial enlargement associated with specific cardiac lesions, such as mitral valve stenosis, mitral valve regurgitation, patent ductus arteriosus , or ventricular septal defect , can render the foramen ovale "incompetent. (medscape.com)
Fetal circulation2
  • In fetal circulation, the foramen ovale functions as a one-way valve that enables blood to flow from the right atrium (RA) to the left atrium (LA) so that oxygenated blood from the placenta can bypass the unaerated lungs and directly enter the fetus' systemic circulation. (allenpress.com)
  • The foramen ovale is essential for proper fetal circulation, directing oxygenated, nutrient-rich blood from the placenta, preferentially to the developing fetal brain. (medscape.com)
Right atrial3
  • At birth, the left atrial pressure exceeds the right atrial pressure and forces the valve against the limbus, thus achieving physiological closure. (medscape.com)
  • Right-to-left shunting can occur through a patent foramen ovale, especially in conditions associated with elevated right atrial pressure such as tricuspid atresia, tricuspid valve stenosis or right ventricular hypoplasia with decreased right ventricle compliance. (medscape.com)
  • Patients with persistent or transient elevation of right atrial pressure can experience a paradoxical embolus through a patent foramen ovale. (medscape.com)
Orthodeoxia2
Interatrial1
  • The foramen ovale is an interatrial communication that permits blood from the inferior vena cava to freely enter the left atrium in utero. (medscape.com)
Congenital1
  • Some congenital heart lesions depend on the foramen ovale for obligatory left-to-right (mitral atresia) or right-to-left ( tricuspid atresia , total anomalous pulmonary venous return ) shunting to maintain adequate cardiac output. (medscape.com)
Outcomes1
  • Impact of hospital volume on outcomes of percutaneous ASD/PFO closure in pediatric patients. (medscape.com)
Naturally after birth2
  • However, if this opening fails to close naturally after birth, the opening is said to remain patent and the condition is called a Patent Foramen Ovale (PFO) a common heart defect that occurs in approximately 20 percent of the population. (salesandmarketingnetwork.com)
  • In the majority of the infants, closure of the foramen ovale occurs naturally after birth as negative intrathoracic pressure caused by the infants' first breaths will cause the PFO to close. (heartvascularcentre.com)
Hypoxemia3
  • A connection between patent foramen ovale and chronic pulmonary disease was first described more than 2 decades ago in case reports associating patent foramen ovale with more severe hypoxemia than that expected based on the severity of the primary pulmonary disease. (allenpress.com)
  • It has been suggested that patients with both chronic pulmonary disease and patent foramen ovale are subject to severe hypoxemia because of the right-to-left shunt. (allenpress.com)
  • This review focuses on the association between chronic pulmonary disease and patent foramen ovale and on the dynamics of a right-to-left shunt, and it considers the potential benefit of patent foramen ovale closure in patients who have hypoxemia that is excessive in relation to the degree of their pulmonary disease. (allenpress.com)
Systemic1
  • Furthermore, investigators have reported improved systemic oxygenation after patent foramen ovale closure in some patients with chronic pulmonary disease. (allenpress.com)
Patients8
  • The successful use of surgical procedures for the treatment of migraine is becoming more frequently reported in the medical literature, particularly for those patients who do not respond to medication. (wikipedia.org)
  • This study evaluated the efficacy and safety of PFO closure in patients with migraine using evidence-based. (deepdyve.com)
  • Several echocardiography and postmortem studies indicate that the foramen remains competent in 30% of patients with otherwise normal cardiac anatomy. (medscape.com)
  • Some thrombophilic patients have been excluded from clinical trials of septal defect closure due to the presumed higher risk of thrombus formation. (structuralheartdisease.org)
  • The purpose of this study was to assess whether pre-existing thrombophilia predisposes patients to adverse events after percutaneous patent foramen ovale (PFO) or atrial septal defect (ASD) closure. (structuralheartdisease.org)
  • Of the closure patients, 1 (1.4%) developed thrombus (Amplatzer ASO device). (structuralheartdisease.org)
  • Percutaneous implantation of a second device in patients with residual right-to-left shunt after patent foramen ovale closure. (unito.it)
  • A multidisciplinary panel published guidance on the optimal length of time to monitor patients for atrial fibrillation before referring for PFO closure. (pfostroke.com)
Incidence2
  • Non-drug treatment, when possible, is preferable because of the high incidence of unpleasant or debilitating side-effects that occur with migraine preventive drugs. (wikipedia.org)
  • Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts. (medscape.com)
Cardiac1
  • The foramen ovale is a normal cardiac structure found in all newborns and can be best described as a "door" between the right and left atria. (medscape.com)
Underwent1
Pulmonary1
  • 5. After ASD closure, if an athlete has pulmonary hypertension, arrhythmias, heart block, or impaired heart function, there must be an individualized approach to the issued of continued participation. (athletesheart.org)
Thrombus1
  • Percutaneous closure can be safely performed without a significant risk of thrombus formation despite the presence of thrombophilic factors. (structuralheartdisease.org)
Device closure3
  • The PFO device closure is performed in a catheterization laboratory with fluoroscopic (live X-ray) and TEE guidance. (heartvascularcentre.com)
  • We call this procedure a percutaneous device closure . (athletesheart.org)
  • 4. After a satisfactory recovery, athletes can participate fully after ASD repair (device closure or surgical) after a period of 3-6 months. (athletesheart.org)
Occur1
  • Because migraine is an exceedingly complex condition, there are various preventive treatments which have their effect by disrupting different links in the chain of events that occur during a migraine attack. (wikipedia.org)
Reduction1
  • However in FDA trials the Nociceptive Trigeminal Inhibition Tension Suppression System (NTI-tss) had been proven to provide a 77% reduction of migraine events in 82% of subjects tested. (wikipedia.org)
Disease1
  • Although it is a normal structure, a foramen ovale has several special circumstances under which it may be implicated in disease. (medscape.com)
Depend1
  • How quickly an athlete may return to their sports will depend upon the particular method of closure and also upon the demands of an athlete's sport. (athletesheart.org)
Decades1
  • However, adult autopsy studies have shown that 20-34% of adults from the third to ninth decades of life have at least a small patent foramen ovale. (medscape.com)
Infant2
Treatment4
  • Migraine treatment may be either prophylactic (preventive) or abortive (rescue). (wikipedia.org)
  • Prevention is better than cure, so the ideal treatment goal is to prevent migraine attacks. (wikipedia.org)
  • Because of the complexity of migraine, no preventive treatment modality is effective for all migraine sufferers. (wikipedia.org)
  • Patent foramen ovale treatment strategy: an Italian large prospective study. (unito.it)
Birth1
Heart5
  • The Coherex FlatStent EF device is designed to close Patent Foramen Ovale (PFO), a common structural heart defect found in approximately 20 percent of the worldwide population, using a percutaneous catheter-based approach. (salesandmarketingnetwork.com)
  • A foramen ovale is a tunnel-like opening between the upper chambers of the heart that allows blood to bypass the lungs while a fetus is in the womb. (salesandmarketingnetwork.com)
  • In some cases, the primum and secundum atrial septa fail to fuse completely, causing the foramen ovale to remain patent, enabling a continuous communication between the left and right heart. (heartvascularcentre.com)
  • We won't consider another type of "hole" between the upper chambers of the heart, the patent foramen ovale (PFO). (athletesheart.org)
  • Ostium secundum and sinus venosus ASDs require conventional heart surgery for closure. (athletesheart.org)
Common3
  • That vasodilatation is an important factor in migraine is further confirmed by the fact that the most widely used migraine rescue medications, the ergots, the triptans, and the promising newer drugs, the gepants, possess one significant common denominator: they all potently constrict abnormally dilated extracranial arteries while simultaneously reducing or eliminating migraine pain. (wikipedia.org)
  • The most common vessels involved in the pain of migraine are the terminal branches of the external carotid artery, and in particular, the superficial temporal artery and its frontal branch, and the occipital artery, but the maxillary, posterior auricular, supra-orbital, and supra-trochlear branches may also be involved. (wikipedia.org)
  • Patent foramen ovale (PFO) is a common abnormality, with an occurrence of 20-34% in the adult population. (heartvascularcentre.com)
Shown2
  • Observational studies have shown percutaneous patent foramen ovale (PFO) closure to be a safe means of reducing the frequency and duration of migraine. (deepdyve.com)
  • Nevertheless, the last metaanalyses of these studies have shown that percutaneous closure of PFO could be beneficial for certain patient groups. (unizar.es)
Years1
  • During the first years of life, the foramen ovale seals shut and becomes a true wall that separates the right and left atria. (medscape.com)
Potential1
  • However, in a significant proportion of people, the foramen ovale does not seal shut and remains a potential trapdoor between the two atria. (medscape.com)
People1
Medical2
  • SALT LAKE CITY--(HSMN NewsFeed)--Salt Lake City-based Coherex Medical, Inc. today announced that it has entered into a multi-year distribution agreement with global health care company Abbott for the Coherex FlatStent(TM) EF PFO Closure System. (salesandmarketingnetwork.com)
  • Coherex Medical will manufacture the Coherex FlatStent EF PFO Closure System at its facility in Salt Lake City. (salesandmarketingnetwork.com)
Population1
Patient1
  • To refer your patient for PFO closure, contact an interventional cardiologist near you. (pfostroke.com)
Remains1
  • The RESPECT trial remains the largest randomized controlled trial on PFO closure. (pfostroke.com)
RESPECT1
  • Recientemente se han publicado estudios aleatorizados, como son el CLOSURE, RESPECT y PC- trial, que no han conseguido demostrar que el cierre percutáneo se asocie a una reducción de ictus en comparación con el tratamiento médico con antiagregantes o anticoagulantes. (unizar.es)
Effective1
  • 94.2% effective PFO closure (n≤9 bubbles at 6 months). (pfostroke.com)
Generally1