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  • genes
  • AβPP-like homologous genes and proteins are highly conserved in various organisms from invertebrates to mammals. (iospress.com)
  • AβPP-like genes undergo similarly pathways of transcription and post-transcription processing, and AβPP-like proteins is proteolyzed by the similar α-cleavage and the β-cleavage pathways. (iospress.com)
  • cyclophilin
  • To this end, we used recombinant adenovirus to overexpress human CD147 (in SH-SY5Y cells and primary cortical neurons), and pre-treated cultures with or without recombinant cyclophilin A (rCYPA) protein, prior to Aβ42 exposure. (edu.au)
  • extracellular
  • This protein is involved in various cellular and biological functions, such as lymphocyte migration and maturation, tissue repair cancer progression, T and B lymphocyte activation, and induction of extracellular matrix metalloproteinase. (iospress.com)
  • CD147
  • Upregulation of CD147 expression was probably mediated by oxidative stress, as H2O2 (3 μM) also induced CD147 protein expression in neuronal cultures. (edu.au)
  • We showed that increased CD147 expression protected against Aβ42, only when rCYPA protein was added to neuronal cultures. (edu.au)
  • compounds
  • Under these conditions high-cell-density biomass containing elevated amounts of valuable compounds such as fatty acids, pigments, proteins, vitamins, and active polysaccharides can be obtained [ 1 ]. (mdpi.com)
  • In nutraceutical industries, Arthrospira ( Spirulina ) and Chlorella are the most important species in commercialization as health foods and nutrition supplements with various health benefits including enhancing immune system activity, anti-tumor effects, and animal growth promotion, due to their abundant proteins, vitamins, active polysaccharides, and other important compounds [ 5 , 6 ]. (mdpi.com)
  • Unlike
  • Unlike many eukaryotic-type proteins from L. pneumophila, neither Lpg1905 nor Lpg0971 were translocated into the host cell by the Dot/Icm (defective in organelle trafficking/intracellular multiplication) type IV secretion system. (jove.com)
  • dependent
  • The secretion of PCSK9 is largely dependent on the autocleavage of the signal peptide and N-terminal prodomain, though the N-terminal prodomain retains its association with the catalytic domain. (wikipedia.org)
  • form
  • CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. (wikipedia.org)
  • Some water-soluble proteins associate with lipid bilayers irreversibly and can form transmembrane alpha-helical or beta-barrel channels. (wikipedia.org)
  • major
  • Such a conformational change would be expected to play a major role both during PTS1 protein recognition as well as in cargo release into the peroxisomal lumen. (biomedcentral.com)
  • animals
  • 7-Dehydrocholesterol is a zoosterol (a sterol produced by animals rather than plants). (hmdb.ca)