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  • cell penetra
  • We found that conjugation of cell penetrating peptide (CPP) to PNA is essential for the antimicrobial effect, with CPP1 [(KFF)3K] being the most effective against E. amylovora . (frontiersin.org)
  • To be used as therapeutics, each novel cell-penetrating peptide needs to be fully characterized, including their physicochemical properties, their biological activity and their uptake mechanism. (diva-portal.org)
  • These findings extend the knowledge of the variables that condition intracellular Cell-penetrating peptide mediated transport of nucleic acids, which ultimately translates into a small step towards successful non-viral gene therapy. (diva-portal.org)
  • calcitonin
  • 1. Binding sites for calcitonin-gene-related peptide were localized and characterized in porcine coronary arteries using quantitative autoradiography, and the density of binding sites was compared between large epicardial and small intramyocardial coronary arteries. (clinsci.org)
  • 2. A single class of binding sites for calcitonin-gene-related peptide with a dissociation constant of 2.1 ± 0.2 nmol/l was detected in both the large and small coronary arteries. (clinsci.org)
  • β-Human calcitonin-gene-related peptide showed higher affinity than α-human calcitonin-gene-related peptide for the binding sites. (clinsci.org)
  • 4. The present findings lend further support to the theory of regional variation in the vasodilator response to calcitonin-gene-related peptide in porcine coronary arteries, which seems to be due to different densities of a single type of receptor for calcitonin-gene-related peptide. (clinsci.org)
  • Distinct substance P and calcitonin gene-related peptide immunoreactive nerves in the guinea pig eye. (arvojournals.org)
  • Using a double labeling indirect immunofluorescent technique, we studied the guinea pig trigeminal ganglion and eye for co-localization of substance P and calcitonin gene-related peptide. (arvojournals.org)
  • In the trigeminal ganglion, the number of neurons immunoreactive for calcitonin gene-related peptide significantly outnumber those immunoreactive for substance P, but virtually all substance P positive neurons are immunoreactive for calcitonin gene-related peptide. (arvojournals.org)
  • Nerve fibers immunoreactive only for calcitonin gene-related peptide tend to be concentrated in the cornea and posterior ciliary body. (arvojournals.org)
  • TOPICAL CALCITONIN GENE-RELATED PEPTIDE INCREASES WOUND CLOSURE IN SECOND DEGREE CUTANEOUS BURNSBiologyMissouri State University, August 2012Master of ScienceDarin Thomas DieckhoffABSTRACTCutaneous thermal wounds result in significant tissue damage with loss of epidermis, nerve fibers, and vascular tissue, which increases healing time. (missouristate.edu)
  • The 37-amino acid neuropeptide calcitonin gene-related peptide (CGRP) is a multifunctional protein that promotes vasodilation and proliferation of keratinocytes and endothelial cells. (missouristate.edu)
  • nucleic
  • We determined that a 10-nucleotide oligomer of peptide nucleic acid (PNA) targeting the start codon region of an essential gene acpP is able to cause complete growth inhibition of E. amylovora . (frontiersin.org)
  • major
  • To assess the long-term prognostic value of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) after major vascular surgery. (bmj.com)