• analogs
  • However, as peptide analogs of GLP-1, these require administration by intravenous or subcutaneous injection and have been associated with significant adverse side effects, including pancreatitis ( Olansky, 2010 ). (aspetjournals.org)
  • transmembrane
  • Particularly, the specific amino acid residues within the transmembrane helices and extracellular loops of the receptor that may confer ligand-induced receptor activation have been poorly investigated. (frontiersin.org)
  • cocaine
  • Here, we report that GLP-1 receptor stimulation reduces acute and chronic cocaine self-administration and attenuates cocaine-induced hyperlocomotion. (sigmaaldrich.com)
  • Effect
  • In contrast to hydroxyl flavonols, catechin had no effect on peptide-mediated Ca 2+ signaling but negatively modulated peptide-mediated cAMP formation in a probe-dependent manner. (aspetjournals.org)