Peptide melittin bee venoms. Medical search. Frequent questions

This venom contains antimicrobial peptides which are effective against a broad range of gram-positive/negative bacteria [ 4 ]. (biomedcentral.com)
The efficacy of antimicrobial peptides derived from the venom on septic and non-septic inflammations, wound healing, and regulation of adaptive immune system have also been studied [ 5 ]. (biomedcentral.com)
Likewise, antimicrobial peptides assist the body in wound healing. (kiyalongevity.com)
Antimicrobial peptides (AMPs) interact with bacterial membranes to induce membrane disruption and protect host cells from bacteria through antimicrobial action. (ncku.edu.tw)
Antimicrobial peptides (AMPs) are a class of promising antibiotic molecules as they present broad action spectrum, potent activity, and do not easily induce resistance. (frontiersin.org)

Scientists have identified amines, enzymes and peptides that are responsible for the pain of - or allergic reaction to - a sting. (howstuffworks.com)
Additionally, two enzymes , hyaluronidase and phospholipase A2 (bvPLA2), together make up between 11 and 15 percent of bee venom. (howstuffworks.com)
Scientific studies have shown that bee venom's natural peptides, enzymes, and proteins positively affect the skin. (beeandyou.eu)
It consists of a mixture of substances, principally of proteins and peptides, including enzymes as well as other types of molecules in a very low concentration. (uvigo.es)
Bee venom consists of 88 % water, and dry matter represents a mixture of peptides, enzymes and low molecular weight compounds. (unizg.hr)
The clear liquid is deceptively innocuous looking, and is basically an essential blend of enzymes, peptides and amino acids. (manukadoctor.co.uk)
Bee Venom is a potent combination of enzymes, peptides and amino acids that works on all levels of the skin to encourage naturally occurring cell regeneration, boost collagen formation and accelerate the recovery of damaged skin cells. (amorfia.online)

Melittin is a basic peptide consisting of 26 amino acids. (wikipedia.org)
Mellition, which is composed of 26 amino acids, is the main toxin molecule of the bee venom. (fountainmagazine.com)
Melittin a 26-amino acid peptide is the most important active constituent of honey bee venom that forms up to 50% of its dry weight [ 6 ], with significant antimicrobial and antiviral properties [ 7 ]. (biomedcentral.com)
Scientifically speaking, they are chains of amino acids held together by peptide bonds. (kiyalongevity.com)
Peptide supplements, lotions, oral sprays, etc. do not have as many amino acids as those found naturally in our bodies. (kiyalongevity.com)
Peptides are amino acids that make up certain proteins needed by the skin. (kiyalongevity.com)
In a study published in the journal „Toxins", researchers at the Hessian LOEWE Center for Translational Biodiversity Genomics (LOEWE-TBG) are now showing another facet of the importance of wild bees: in their venoms, which have been little studied so far, they were able to detect more original variants of melittin, a peptide of 26 amino acids and major component of bee venom. (senckenberg.de)
However, how the amino acid sequence of melittin contributes in its anti-inflammatory properties is mostly unknown. (blogspot.com)
Two of these analogues namely, melittin Mut-1 (MM-1) and melittin Mut-2 (MM-2) possess leucine to alanine substitutions in the single and double heptadic leucine residue(s) of melittin respectively while the third analogue is a scrambled peptide (Mel-SCR) which contains the amino acid composition of melittin with minor rearrangement in its leucine zipper sequence. (blogspot.com)
Peptides are chains of amino acids that act as cell signaling molecules. (mediproholistichealth.com)

Melittin is the main component (40-60% of the dry weight) and the major pain-producing substance of honeybee (Apis mellifera) venom. (wikipedia.org)
Honey Bee Venom (Apis mellifera) contains Anti-coagulation Factors and Increases the Blood-clotting time. (apihealth.com)
the candidate bees are all honey bees from the genus Apis: Apis mellifera from Europe, Eastern Mediterranean lands and Africa: Apis cerana the hive bee in Asia, and Apis dorsata, Apis florea and related species in the tropics of Asia. (positivehealth.com)
Bee venom is a clear, odorless liquid substance secreted from the venom glands in the abdomen of worker bees (Apis mellifera L.) and collected in the venom sac located at the base of the bee's stinger. (beeandyou.eu)
Venoms obtained from Apis mellifera (honey bee) and related species. (lookformedical.com)
When we hear about bees, in most cases only the honeybee ( Apis mellifera ) is mistakenly associated. (senckenberg.de)

Since a limited number of studies regarding the effects of melittin on the immune system have been carried out, we aimed to evaluate the effects of melittin on BALB/c mice immune system parameters. (biomedcentral.com)

Melittin and phospholipase A2 (PLA2) are the most abundant and studied compounds of BV. (uvigo.es)
Melittin causes the release of lecithin from red blood cells, which is transformed into lysolecithin through the action of phospholipase A2, causing hemolysis [ 14 ]. (biomedcentral.com)

At the sites of multiple stings, localized pain, swelling, and skin redness occur, and if bees are swallowed, life-threatening swelling of the throat and respiratory passages may develop. (wikipedia.org)
in doing so, the bee, instinctively, stings (although some may require a little nudge - most honey bees aren't aggressive until you provoke them). (howstuffworks.com)
Puppies, with their small bodies, may be more severely affected by bee stings especially if they are stung multiple times. (schoolofbees.com)
Bagonza said they can also conduct Apipuncture, where one is subjected to bee stings for a given period of time to boost immunity using the venom. (tuckmagazine.com)
When a bee stings an animal flesh and holds, it struggles and the whole depositor breaks out and a bee bleeds to death between 40 minutes to two hours. (tuckmagazine.com)
Individuals allergic to bee stings should avoid using bee venom in any form. (beeandyou.eu)
When a bee stings, it usually dies, as the stinger is left behind. (manukadoctor.co.uk)
When threatened, they can deliver painful stings that release venom into the attacker. (petexperta.com)
We report three cases of stings by Africanized bees in cattle in the state of Rio de Janeiro, Brazil. (biomedcentral.com)
Although the occasional occurrence of bee stings in cattle in the fields has been verbally reported by veterinarians, owners, and handlers, we have failed to find clinicopathological descriptions of bee stings in cattle. (biomedcentral.com)
Aside from scientific proof, I have come across many a beekeeper who has experienced relief from bee stings. (thehivewisdom.com)

Dr. Weeks' Comment: Since pioneering apitherapy in the USA - as founder of the American Apitherapy Society, it has been a privilege to watch the scientific community become increasingly enamored with the therapeutic potential of venoms in general and honeybee venom in particular. (weeksmd.com)
Honeybee venom has been used in traditional medicine for centuries as an anti-inflammatory. (senckenberg.de)
Melittin from honeybee venom has long been known to have a strong effect in laboratory experiments. (senckenberg.de)
Results published in the prestigious international journal npj Precision Oncology revealed that honeybee venom rapidly destroyed triple-negative breast cancer and HER2-enriched breast cancer cells. (azolifesciences.com)
Dr Duffy said the aim of the research was to investigate the anti-cancer properties of honeybee venom, and a component compound, melittin, on different types of breast cancer cells. (azolifesciences.com)
No-one had previously compared the effects of honeybee venom or melittin across all of the different subtypes of breast cancer and normal cells. (azolifesciences.com)
We tested honeybee venom on normal breast cells, and cells from the clinical subtypes of breast cancer: hormone receptor positive, HER2-enriched, and triple-negative breast cancer. (azolifesciences.com)
We tested a very small, positively charged peptide in honeybee venom called melittin, which we could reproduce synthetically, and found that the synthetic product mirrored the majority of the anti-cancer effects of honeybee venom,' Dr Duffy said. (azolifesciences.com)
We found both honeybee venom and melittin significantly, selectively and rapidly reduced the viability of triple-negative breast cancer and HER2-enriched breast cancer cells. (azolifesciences.com)
A specific concentration of honeybee venom can induce 100% cancer cell death, while having minimal effects on normal cells. (azolifesciences.com)
We looked at how honeybee venom and melittin affect the cancer signalling pathways, the chemical messages that are fundamental for cancer cell growth and reproduction, and we found that very quickly these signalling pathways were shut down. (azolifesciences.com)
This is an incredibly exciting observation that melittin, a major component of honeybee venom, can suppress the growth of deadly breast cancer cells, particularly triple-negative breast cancer. (azolifesciences.com)
I began with collecting Perth honeybee venom. (azolifesciences.com)
While there are 20,000 species of bees, Dr Duffy wanted to compare the effects of Perth honeybee venom to other honeybee populations in Ireland and England, as well as to the venom of bumblebees. (azolifesciences.com)

We report that simple, synthetic organic polymer nanoparticles (NPs) can capture and clear a target peptide toxin in the bloodstream of living mice. (bibliotecapleyades.net)
In vivo imaging of the polymer nanoparticles (or 'plastic antibodies') established that the NPs accelerate clearance of the peptide from blood and accumulate in the liver. (bibliotecapleyades.net)
The positive results from cloaking these venoms in nanoparticles could lead to human trials in then next three to five years. (issels.com)
He says that synthetic peptides mimicking components from other venoms, such as those from snakes or scorpions, also work well in the nanoparticles as a possible cancer therapy. (scienceblog.com)
Free melittin and melittin-loaded nanoparticles were prepared and compared for cytotoxicity and their ability to inhibit infectivity by CXCR4 and CCR5 tropic HIV-1 strains. (msu.edu)
Melittin-loaded nanoparticles were formulated and different doses tested against VK2 vaginal epithelial cells to determine cell viability. (msu.edu)
Based on VK2 viability, melittin nanoparticles were tested for prevention of CXCR4 and CCR5 tropic HIV-1 infectivity and viability of TZM-bl reporter cells. (msu.edu)
Low-speed centrifugation was used to compare the ability of blank non-melittin nanoparticles and melittin nanoparticles to capture CCR5 tropic HIV-1. (msu.edu)
However, VK2 cell viability was not affected at any dose of melittin-loaded nanoparticles. (msu.edu)
Melittin nanoparticles safely and significantly decreased CXCR4 (IC(50) 2.4 μM and IC(90) 6.9 μM) and CCR5 (IC(50) 3.6 μM and IC(90) 11.4 μM) strain infectivity of TZM-bl reporter cells. (msu.edu)
Furthermore, melittin nanoparticles captured more HIV-1 than blank nanoparticles. (msu.edu)
Future investigations appear warranted to explore the antiviral prophylactic potential of melittin nanoparticles to capture, disrupt and prevent initial infection with HIV-1 or potentially other enveloped viruses. (msu.edu)

Melittin is a peptide found in bee venom that is known for its potential to inhibit the release of certain neurotransmitters. (yeardourshop.com)
The active biological protein called melittin found in bee venom was found to be effective in inhibiting excessive proliferation and necrosis of keratinocytes - the main problem in psoriasis. (woomlo.com)

More than one toxin is released during a honey-bee sting, though. (howstuffworks.com)

The use of these products explains the amazing honey bee success. (positivehealth.com)
The usefulness of honey bee products for people is based on the same properties that make these products useful for the bees themselves. (positivehealth.com)
A comprehensive review on the history of the honey bee is given by Crane. (positivehealth.com)
The goal of this review is to examine the chemistry, properties and applications of honey bee products. (positivehealth.com)
Bee sting therapy, commonly called bee venom therapy (BVT), is the medical use of the toxic compounds in honey-bee venom (BV), also known as apitoxin, in a therapeutic way. (howstuffworks.com)
Modern practitioners often still use the live honey bee herself as the delivery vehicle for venom. (howstuffworks.com)
Only 22 percent of honey-bee venom is pharmacologically active - the remainder is just water. (howstuffworks.com)
The honey bee does not only produce honey. (fountainmagazine.com)
Honey bee venom is a valuable natural compound which is suggested (in studies) as a candidate for the treatment of various ailments such as arthritis, gout, rheumatism, and other disorders related to the immune system [ 3 ]. (biomedcentral.com)
Bees are typically not aggressive creatures if you leave them alone, although, in reality, the same cannot be said for the Africanized Honey Bee species. (schoolofbees.com)
In this study, we conducted a series of molecular dynamics simulations using all-atom (AA) or coarse-grained molecular dynamics (CG-MD) simulations to reveal actions of melittin, a typical AMP derived from honey bee venom, on lipid membranes. (ncku.edu.tw)
Honey bee products deserve further funds to uncover these important discoveries which continue to elevate the merits of Apitherapy. (blogspot.com)

The two venom molecules, melittin and secapin, that are over-expressed in honey bees infected with various pathogens, possibly indicate a role for melittin in the immune response of bees to infectious diseases. (wikipedia.org)
The direct insertion of melittin leads to pore formation, whereas the parallel conformation is inactive and prevents other melittin molecules from inserting, hence preventing pore formation. (nih.gov)
18 different bioactive molecules were found in the composition of bee venom. (fountainmagazine.com)
Some of them are known from the honeybee, others we have newly discovered through our combined analysis of the molecules, the proteins, and the genome of the wild bee venom. (senckenberg.de)
Arthropods also include scorpions, from which several bioactive molecules have been isolated from the venom glands. (frontiersin.org)
We found that melittin can be used with small molecules or chemotherapies, such as docetaxel, to treat highly-aggressive types of breast cancer. (azolifesciences.com)

Venom from snakes, bees and scorpions contains proteins and peptides which, when separated from the other components and tested individually, can attach to cancer cell membranes. (scienceblog.com)

As gathered by the honeybee pollen is a very beneficial natural food and promoter of good health, which has been used by man for many centuries. (apihealth.com)
No other natural product on earth could compete with bee pollen in the level of nutritional value. (apihealth.com)
ApiHealth extraction technology with breaking pollen shells allows to achieve higher level of biological active ingredients from bee pollen and make them more available for the body. (apihealth.com)
1 Protective Effect of Polyphenol-Rich Extract from Bee Pollen in a High-Fat Diet . (apihealth.com)
2. Antioxidant Potential of Propolis, Bee Pollen, and Royal Jelly: Possible Medical Application. (apihealth.com)
Their success in the animal kingdom is largely because of the chemistry and the applications of their products: honey, beeswax, bee venom, propolis, pollen, and royal jelly. (positivehealth.com)
The other three (honey, propolis and pollen) are derived from plants and are modified and engineered by the bees for their own use. (positivehealth.com)
Without these unique products honey bees probably would have evolved to be little different from their ancestors - solitary bees in which each female bee during a brief season provisions a few cells with pollen and nectar for the next generation. (positivehealth.com)
BV therapy is part of a larger medical philosophy and treatment called apitherapy (bee therapy), a type of holistic therapy that uses not only bee venom for its healing properties, but several bee products, including beeswax, honey, pollen, propolis (bee glue) and royal jelly in treatments. (howstuffworks.com)
Honey bees are primarily used for the production of honey, beeswax, royal jelly, propolis, bee pollen and bee venom. (unizg.hr)
Bee Pollen For Seasonal Allergies: A Cure Or Just A Myth? (thehivewisdom.com)

Only its main component, melittin, has been scientifically well researched. (senckenberg.de)
The venom of wild bees such as the violet carpenter bee ( Xylocopa violacea ), with its main component melittin, is less aggressive than that of honeybees, a team from the LOEWE Centre TBG discovered. (senckenberg.de)

Three of these products: beeswax, venom, and royal jelly, are chemically synthesised by the bees themselves. (positivehealth.com)
Brazilian green propolis, a beeswax product, has been shown to exhibit multiple actions on inflammation and tissue repair. (blogspot.com)

Histamine and hyaluronidase in the venom are responsible for the diffusion of the poison within the victim by decreasing blood pressure and increasing vascular permeability [ 13 ]. (biomedcentral.com)

Melittin inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase, and Na+/K+-ATPase (synaptosomal membrane). (wikipedia.org)
The scientists were able to separate the useful peptides and protein from the venom, making them target specifically the malignant cells and evading ones that were healthy. (weeksmd.com)
To investigate the effect of protein-to-lipid (P/L) ratios on the antimicrobial action, we also carried out CG-MDs of melittin peptides adsorbed on a lipid membrane at different P/L ratios. (ncku.edu.tw)
Melittin, a protein fraction that causes pain and inflammation, is responsible for the overall toxic effect of the venom by preventing the action of cholinesterase at neuromuscular and ganglionic synapses, causing respiratory paralysis and fibrinogen coagulation [ 13 , 14 ]. (biomedcentral.com)
We have performed molecular dynamics (MD) simulation of the thermal denaturation of one protein and one peptide-ubiquitin and melittin. (typeset.io)

Bee venom has proven anti-inflammatory and anti-nociceptive properties and a beneficial effect when used as a treatment for inflammatory diseases, neurodegenerative diseases, tumors, pain, bacterial and viral diseases, allergic symptoms, as well as antioxidative effects. (unizg.hr)
To determine the importance of the leucine zipper sequence of melittin in its neutralization of LPS-induced inflammatory responses in macrophages and interaction with LPS, anti-inflammatory properties of melittin and its three analogues and their interactions with LPS were studied in detail. (blogspot.com)

The synthetic peptides are able to target and attach directly to cancer stem cell preventing them from spreading or growing, in a lab setting. (weeksmd.com)

There are many potentially useful peptides for pain management depending on the primary issue and degree of secondary contributions. (mediproholistichealth.com)
Useful peptides for pain include Thymosins, ARA290, BPC157, pentosan polysufate and a unique peptide derived from venom, melittin . (mediproholistichealth.com)

Melittin is the main compound in bee venom, accounting for the potential lethality of a bee sting, which causes an anaphylactic reaction in some people. (wikipedia.org)
As a result of binding and removal of melittin by NPs in vivo, the mortality and peripheral toxic symptoms due to melittin [bee venom compound] were significantly diminished. (bibliotecapleyades.net)
When used cosmetically, it fights the signs of ageing as it 'fools' the skin into thinking it has been lightly stung with the compound melittin, stimulating the production of collagen and elastin. (amorfia.online)

According to our results, melittin at 0.75 and 1.5 mg/kg doses could not induce significant changes on immune parameters and as a result, melittin was found to be safe for the mice immune system. (biomedcentral.com)
However, bumblebee venom was unable to induce cell death even at very high concentrations. (azolifesciences.com)

The rise of drug resistance has necessitated the search for novel pharmacologically active substances, making bee products an appealing avenue for research. (debuglies.com)
Pan and his team say that some of substances found in any of these venoms could be effective anti-tumor agents. (scienceblog.com)
Nonetheless, peptides are naturally occurring substances found throughout nature. (kiyalongevity.com)
His colleague Dr. Pelin Erkoc-Erik, first author of the publication, explains: „We examined the effects of melittin peptides on cell damage and the release of messenger substances and inflammatory markers - in both cancerous and non-cancerous human cells. (senckenberg.de)
One of the substances that caught the team's attention was melittin from the violet carpenter bee, a wild bee species. (senckenberg.de)
With these melittin variants, there is no need to compensate for the strong toxicity with inhibitory substances. (senckenberg.de)

Melittin triggers the synthesis of the cortisol hormone that suppresses inflammation and increases the resistance of cell walls. (fountainmagazine.com)
Bee venom (BV) is usually associated with pain since, when humans are stung by bees, local inflammation and even an allergic reaction can be produced. (uvigo.es)
The Pharmacological Potential of Novel Melittin Variants from the Honeybee and Solitary Bees against Inflammation and Cancer. (senckenberg.de)
Formic acid: The venom may contain formic acid, which can cause a burning sensation and inflammation when injected into a predator or prey. (petexperta.com)

Scientists are interested in unraveling the chemical components of the venom and how they contribute to the ant's predatory behavior and defense mechanisms. (petexperta.com)

The researchers discovered that venom from snakes, scorpions, and bees contain peptides and proteins that will attach to cancer cell walls. (issels.com)
Researchers have also tried to alleviate different allergic reactions brought by the use of melittin through altering its molecular structure to reduce its possible side effects [ 6 ]. (biomedcentral.com)
The lead author of the study from the University of Illinois said the researchers safely used toxins from venom in tiny nanometer particles to treat melanoma and breast cancer cells in a lab setting. (weeksmd.com)
However, researchers have not been able to harness the promising properties of anti-cancer into the form of a drug, because the injection of venom likely would cause side effects that could be serious such as nerve cell and heart muscle damage, bleeding beneath the skin and unwanted clotting. (weeksmd.com)
When the researchers examined venom from a honeybee, they identified melittin, a substance that prevents the multiplying of cancer cells. (weeksmd.com)
A team of researchers from Frankfurt am Main and Giessen has now discovered milder melittin variants in evolutionarily older wild bee species that seem to be more usable for pharmacology. (senckenberg.de)
The researchers agree that the melittin peptides discovered in the wild bee species indeed reveal new and less aggressive activities and thus possibly promise potential for future pharmaceutical applications. (senckenberg.de)
By studying the venom, researchers hope to gain insights into potential medical applications and develop new treatments for various conditions. (petexperta.com)
In 2008, at the Department of Arthropathy, Zhejiang Provincial Hospital of Integrated Chinese and Western Medicine, Hangzhou, researchers found that a combined application of bee venom therapy and medication was superior to the sole use of medication in relieving rheumatoid arthritis , and that bee sting therapy can reduce both the need for western medication and the number of relapses. (thehivewisdom.com)

Bee venom therapy has been used in traditional medicine for treating various disorders, although its non-specific toxicity has limited scientific research on its potential effects. (wikipedia.org)
These products, as well as honey, have been used as complimentary therapy (apitherapy) for medical applications. (fountainmagazine.com)
This article explores the multifaceted world of apitherapy, focusing on bee venom therapy and its potential applications in both human and veterinary medicine. (debuglies.com)

More specifically, collagen is made of three polypeptide chains, so adding peptides can stimulate your skin to make collagen. (kiyalongevity.com)

The principal function of melittin as a component of bee venom is to cause pain and destruction of tissue of intruders that threaten a beehive. (wikipedia.org)
This takes the venom directly to the targeted cancer cells without allowing it to leak into the bloodstream of patients and damage the heart, nerve cells, or other healthy tissue. (issels.com)
Melittin also triggers the immune system cells that prevent the formation of free radicals, which normally damage cells and tissue. (fountainmagazine.com)
In addition, other peptides are believed to boost the growth of muscle tissue and help repair and restore muscles after exercise. (kiyalongevity.com)
It seems that the main reason for effectiveness of royal jelly on the skeletal tissue of the body, bones, and teeth is related to its high calcium concentration, and due to that, RJP has been widely used in traditional oriental medicine (Guo et al. (researchgate.net)
After three weeks of intensive research and extraction in June 2023, I found that bee venom produced by New Zealand honey bees quickly integrates into human skin tissue. (woomlo.com)

Subsequently, supramolecular structures became visible by microscopy, revealing amyloid-like fibrils composed of both the activating peptide and PLA2. (uu.nl)

You might feel unlucky because you got stung, but the bee who's stung got embedded on your skin is the unluckier one. (schoolofbees.com)
The reason why your cat might get stung by a bee is when he tries to swat or play with the insect, stumble upon a hive or just plainly in the wrong place at the wrong time. (schoolofbees.com)
You'll be able to determine if your dog is stung by a bee if you find him scratching and biting a certain area of his body and if upon closer inspection, you see red, swollen skin on your dog. (schoolofbees.com)
The first time I got stung was while filming Dee Lusby, the Queen Bee of Organic Farming, in the remote desert rangeland of southern Arizona. (thehivewisdom.com)
You got stung by African bees," Dee mused. (thehivewisdom.com)

and royal jelly is a balanced food source that does not spoil readily and is used to feed bee larvae. (positivehealth.com)
Royal jelly is a secretion product of the cephalic glands of nurse bees that has been used for centuries for its extraordinary properties and health effects. (researchgate.net)
Royal jelly is one of the most studied bee products, but there still remains much to reveal about its biochemistry and biological activity in future research for our health and life benefit. (researchgate.net)

We show that in membranes composed of zwitterionic lipids, i.e. phosphatidylcholine, melittin not only forms pores but also inhibits pore formation. (nih.gov)
Snake, scorpion and bee venom has peptide and proteins that are able to attach to the membranes of cancer cells. (weeksmd.com)
We performed AA-MDs of lipid membranes in the presence of multiple melittin peptides to estimate the free energy required to form a membrane pore. (ncku.edu.tw)
The CG-MD simulations using the CG model showed that three different modes were observed depending on the P/L ratio and the local arrangement of peptides on the membranes: toroidal pore formation, lipid extraction and budding, and bursting. (ncku.edu.tw)
We found that melittin can completely destroy cancer cell membranes within 60 minutes. (azolifesciences.com)
Dr Duffy also tested to see if melittin could be used with existing chemotherapy drugs as it forms pores, or holes, in breast cancer cell membranes, potentially enabling the entry of other treatments into the cancer cell to enhance cell death. (azolifesciences.com)

Bee venom support the immune system in health condition and contribute production of endogenous cortisol in the adrenal glands, which protect body from unfavourable environmental factors and provide joint mobility support. (apihealth.com)

Bees produce such a small amount of venom that extracting a sufficient amount of the substance from them for laboratory testing or clinical use is impractical. (issels.com)
The amount of venom in a bee varies depending on the season and the bee's structure, ranging from 0.05-0.3 ml/bee. (beeandyou.eu)

In the tropics of all continents there are stingless bees (Meliponinae), some 500 species in all. (positivehealth.com)
Wild bees, on the other hand, are only slowly humming their way into our consciousness, although they make up by far the most species in the group of bees and many plant species depend exclusively on wild bees as pollinators. (senckenberg.de)
Welcome to your friendly guide on ant venom and species! (petexperta.com)
Ant venom is a diverse and captivating subject that encompasses a wide variety of species. (petexperta.com)
By studying their venom composition , scientists can develop targeted strategies for controlling Argentine ant infestations and minimizing their potential harm to native species and environments. (petexperta.com)
The venom of carpenter ants is a complex mixture of chemicals that can vary between species. (petexperta.com)

Natural compounds have long been used due to their benefits for the immune system. (biomedcentral.com)
Since melittin has multiple claimed therapeutic features and in other side, there is a limited number of studies regarding its effects on the immune system, we aimed to evaluate the immunotoxic/immunomodulatory properties of melittin in BALB/c mice with a tiered approach immunotoxicity screening. (biomedcentral.com)
Bee venom has been used to bolster the immune system, treat arthritis, multiple sclerosis, and has been demonstrated to fight cancer and HIV. (thehivewisdom.com)

Based on a research article published in the International Journal of Dermatology in May 2023, I made a remarkable discovery regarding the effects of bee venom on the human body. (woomlo.com)

Apitherapy is a comprehensive term used to describe a group of therapeutic and preventative procedures that utilize various bee products to improve health in both humans and animals. (debuglies.com)
The therapeutic effects of bee products can fluctuate based on various factors, including soil, climate, harvesting and storage practices, and botanical sources. (debuglies.com)
Acacia honey is a natural product which has proven to have therapeutic effects on skin wound healing, but its potential healing effects in corneal wound healing have not been studied. (blogspot.com)

Or tap into this year's biggest beauty trend with the Anti-Pollution range - we're all focused on fighting the effects of our environment - which includes a Recovery Night Cream , containing Purified Bee Venom to boost elasticity. (manukadoctor.co.uk)

Bee venom is believed to stimulate collagen synthesis in the skin. (yeardourshop.com)
Collagen peptides are a natural part of maintaining healthy skin. (kiyalongevity.com)
The peptides contribute to production of both collagen and elastin, two components that keep the skin healthy and vibrant. (kiyalongevity.com)
In fact, when applied to skin, Purified Bee Venom has been actually shown to increase production of vital collagen producing cells, within a short space of time. (manukadoctor.co.uk)
A key anti-ageing ingredient is melittin 3 , which helps the skin to produce collagen and elastin, both of which plump up the complexion, as well as helping to maintain youthful elasticity. (manukadoctor.co.uk)

In the last few decades, our understanding of the chemical composition of bee venom has progressed and numerous studies about the effects of bee venom and its components on human and animal health have been conducted. (unizg.hr)

She was making a point that these "Africanized bees," also known as "killer" bees were not as aggressive as most claimed. (thehivewisdom.com)

This comprises of an organ called the venom gland. (tuckmagazine.com)

Bees were forced to sting hard surfaces, such as plastic or rubber, for venom collection, a practice that was fatal to the bee when her stinger inevitably separated from her abdomen after hard-surface-stinging injuries. (howstuffworks.com)
At the tail end of the bee abdomen is the part called the ovipositor. (tuckmagazine.com)
The bees were put to sleep with carbon dioxide and kept on ice before the venom barb was pulled out from the abdomen of the bee and the venom extracted by careful dissection,' she said. (azolifesciences.com)

One of which is bee venom that contains a peptide called melittin having antimicrobial and anticancer effects. (biomedcentral.com)

All Peptide products have been scientifically engineered to be absorbed into the body orally with no more painful injections. (kiyalongevity.com)

They have devised a method for targeting venom proteins specifically to malignant cells while sparing healthy ones, which reduces or eliminates side effects that the toxins would otherwise cause. (scienceblog.com)

Consider yourself lucky if your dog belongs to the majority that is not allergic to bee venom. (schoolofbees.com)

Scorpion venom has a long history in both ancient Egyptian medicine and in traditional Chinese medicine. (howstuffworks.com)
Bee, snake or scorpion venom could form the basis of a new generation of cancer-fighting drugs, scientists will report here today. (scienceblog.com)

Merrifield, Bruce (1921-2006) was an American biochemist who won the Nobel Prize in Chemistry in 1984 for the invention of solid-phase peptide synthesis. (rockefeller.edu)

We investigated whether cytolytic melittin peptides could inhibit HIV-1 infectivity when carried in a nanoparticle construct that might be used as a topical vaginal virucide. (msu.edu)

While being able to kill cancer cells and prevent them from multiplying is good news by itself, another important breakthrough is Dr Pan's success at concentrating the focus of scorpion, snake, and bee venom on the cancer cells without destroying healthy cells and ultimately harming the patient. (issels.com)
Scorpion, snake and bee venom might sound like more of a health nightmare and not a cure, but the three could be used in drugs that are made to fight cancer, a recent study shows. (weeksmd.com)

In this article, I will take you on a fascinating journey through the world of ants, exploring the different types of ant venom , their effects, composition, properties, and ongoing research in this exciting field. (petexperta.com)
Understanding the composition, properties, and effects of ant venoms is a key focus of ongoing research. (petexperta.com)
Ongoing research is being conducted to understand the composition and properties of Argentine ant venom. (petexperta.com)
The composition and properties of Argentine ant venom are still being explored, and there is much to learn about its potential uses in medicine and other fields of research. (petexperta.com)
Research on carpenter ants and their venom is being conducted to understand the composition and properties of their venom. (petexperta.com)
Understanding their venom composition and properties can help in developing effective pest control strategies," says Dr. Emily Johnson, a leading researcher in ant venom studies. (petexperta.com)
Further research is needed to fully understand the composition and effects of carpenter ant venom. (petexperta.com)

Using the venom from 312 honeybees and bumblebees in Perth Western Australia, Ireland and England, Dr Ciara Duffy from the Harry Perkins Institute of Medical Research and The University of Western Australia, tested the effect of the venom on the clinical subtypes of breast cancer, including triple-negative breast cancer, which has limited treatment options. (azolifesciences.com)

Although the mechanisms of the antimicrobial actions have been studied in experiments and simulations, understanding of the mechanism at the molecular level has not been developed due to the complexity of the antimicrobial action. (ncku.edu.tw)
Equilibrium molecular dynamics simulations, in which proteins spontaneously and repeatedly fold and unfold, have recently been used to help elucidate the mechanistic principles that underlie the folding of fast-folding proteins. (typeset.io)
Ubiquitin folding has been the subject of many experimental studies, but its slow folding rate has made it difficult to observe and characterize the folding process through all-atom molecular dynamics simulations. (typeset.io)

Melittin is toxic to humans and destructive because it pokes holes in cell walls. (howstuffworks.com)

The recent compre- hensive review of the properties and applications of bee products is the proceedings of the International Conference on : "Bee Products: Properties, Applications and Apitherapy" held in Tel Aviv, Israel, May 1996. (positivehealth.com)
A clay tablet that dates back to 2000-2100 BC describes the healing properties of bee venom. (fountainmagazine.com)
In recent years, the medicinal and nutritional properties of hive products have been studied extensively. (debuglies.com)
Other properties such as antioxidant, antimicrobial, neuroprotective or antitumor effects have also been assessed, both in vitro and in vivo. (uvigo.es)
Pharmacological properties are expressed after applying the bee venom or its components, and their expression depends on both the way of application and the location of the application, and it is often applied at acupuncture points. (unizg.hr)
The future of ant venom studies holds exciting prospects for uncovering new components and techniques for studying venom properties. (petexperta.com)
The combination of these ingredients, along with the powerful properties of bee venom, offers a breakthrough solution that tackles psoriasis at its core. (woomlo.com)

We have safely used venom toxins in tiny nanometer-sized particles to treat breast cancer and melanoma cells in the laboratory," says Dipanjan Pan, Ph.D., who led the study. (scienceblog.com)

Anatomy4

Organisms1

Diseases1

Chemicals and Drugs17

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes2

Technology, Industry, Agriculture1

Information Science1

Antimicrobial peptides5

Enzymes7

Amino10

Apis6

Regarding the effects of melittin1

Phospholipase2

Stings11

Honeybee venom14

Nanoparticles12

Found in bee venom2

Toxin1

Honey bee12

Molecules6

Proteins and peptides1

Pollen11

Component melittin2

Beeswax2

Hyaluronidase1

Protein5

Anti-inflammatory2

Synthetic peptides1

Useful peptides2

Compound3

Induce2

Substances6

Inflammation4

Components of the venom1

Researchers9

Therapy3

Polypeptide1

Tissue6

PLA21

Stung5

Royal Jelly3

Membranes6

Glands1

Amount of venom2

Species6

Immune system3

20231

Therapeutic3

Boost elasticity1

Collagen5

Effects of bee1

Aggressive1

Comprises1

Abdomen3

Anticancer1

Injections1

Malignant cells1

Allergic to bee1

Scorpion venom2

Synthesis1

Inhibit1

Snake2

Composition7

Honeybees1

Molecular3

Toxic1

Properties7

Safely1