• The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. (nih.gov)
  • The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. (nih.gov)
  • The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. (nih.gov)
  • Thermodynamic Additivity for Impacts of Base-Pair Substitutions on Association of the Egr-1 Zinc-Finger Protein with DNA. (utmb.edu)
  • Intriguingly, rpAD-specific disturbances were found in the localization of G2L2 and its associated proteins i.e., the end binding protein 1, α-tubulin, and β-actin. (biomedcentral.com)
  • Fortunately, we identified Caspr1 (contactin associated protein 1), anchored at the plasma membrane of BMECs, as a novel binding partner of bacterial IbeA. (microbialcell.com)
  • Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (accession number P19490) produced recombinantly in E. Coli. (antibodiesinc.com)
  • folliculin interacting protein 1. (gsea-msigdb.org)
  • Description: Quantitativesandwich ELISA kit for measuring Human Protein jagged-1 (JAG1) in samples from serum, plasma, tissue homogenates. (kits-elisa.com)
  • Purified GST fusion proteins of the N and C termini of Na v 1.3 pull down contactin from lysates of transfected HEK 293 cells. (jneurosci.org)
  • Based on the results that extracellular aa 203-355 of Caspr1 bind with IbeA, we tested the blocking effect of recombinant Caspr1(203-355) peptides in neonatal rat model of meningitis. (microbialcell.com)
  • The results showed that Caspr1(203-355) peptides effectively attenuated E. coli penetration into the brain during meningitis, indicating that Caspr1(203-355) peptides could be used to neutralize the virulent IbeA to prevent meningitis. (microbialcell.com)
  • Previous case reports have suggested an association between patients with anti-contactin-1 (CNTN1)-mediated neuropathies and MGN. (lu.se)
  • CNTN1 peptides were identified in glomeruli by mass spectroscopy. (lu.se)
  • We show that CNTN1, found in peripheral nerves and kidney glomeruli, is a common target for autoantibody-mediated pathology and may account for between 1 and 2% of idiopathic MGN cases. (lu.se)
  • Bulk Order Inquiry for Anti-Contactin/F3 Antibody FL550 Conjugate ------- (please add any order requirements, including desired quantity, timing, etc. (antibodiesinc.com)
  • Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN 3 . (alomone.com)
  • Anti- L1CAM (extracellular) Antibody (#ANR-047), (1:200). (alomone.com)
  • Anti-L1CAM (extracellular) Antibody, preincubated with L1CAM (extracellular) Blocking Peptide (BLP-NR047). (alomone.com)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Enhancer Of Zeste Homolog 1 (EZH1) in Tissue homogenates and other biological fluids. (1elisakits.com)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Hepatocyte Nuclear Factor 1 Alpha (HNF1a) in Tissue homogenates, cell lysates and other biological fluids. (wildpalm.net)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Hepatocyte Nuclear Factor 1 Alpha (HNF1a) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (wildpalm.net)
  • Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Cattle Vasoactive Intestinal Peptide (VIP) in samples from Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species. (antibody-tech.com)
  • Peptide (C)EDKEMAPEKWYSLGK, corresponding to amino acid residues 653 - 667 of human L1CAM (Accession P32004 ). (alomone.com)
  • α2δ-1 switches the phenotype of synaptic AMPA receptors by physically disrupting heteromeric subunit assembly. (antibodiesinc.com)
  • Small peptides containing the RGD sequence can modulate a variety of cell adhesion invents associated with thrombosis, inflammation, and tumor metastasis. (embl.de)
  • Description: A sandwich ELISA kit for detection of Enhancer Of Zeste Homolog 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (1elisakits.com)
  • Description: A sandwich quantitative ELISA assay kit for detection of Mouse Enhancer Of Zeste Homolog 1 (EZH1) in samples from tissue homogenates or other biological fluids. (1elisakits.com)
  • Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Vasoactive Intestinal Peptide (VIP) in samples from serum, plasma or other biological fluids. (antibody-tech.com)
  • Description: Quantitativesandwich ELISA kit for measuring Rat Vasoactive Intestinal Peptide, VIP in samples from serum, plasma, tissue homogenates. (antibody-tech.com)
  • Description: A sandwich ELISA kit for detection of Hepatocyte Nuclear Factor 1 Alpha from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (wildpalm.net)
  • Description: Quantitativesandwich ELISA kit for measuring Rat Hepatocyte nuclear factor 1-alpha (HNF1A) in samples from serum, plasma, cell culture supernates, tissue homogenates. (wildpalm.net)
  • Notably, these latter phenotypes are recapitulated in pure cultures of JNK1 KO OPCs and of WT OPCs treated with the JNK inhibitor D-JNKI-1. (nature.com)
  • Moreover, JNK1 KO and WT D-JNKI-1 treated OLs, while not showing overt alterations of differentiation in vitro, display a reduced surface compared to controls. (nature.com)
  • In this study we show that contactin coimmunoprecipitates with Na v 1.3 from postnatal day 0 rat brain where this channel is abundant, and from human embryonic kidney (HEK) 293 cells stably transfected with Na v 1.3 (HEK-Na v 1.3). (jneurosci.org)
  • Familia de proteoglicanos heparan sulfato de la superficie celular anclados por GLICOSILFOSFATIDILINOSITOL, que pueden desempeñar un papel en los PROCESOS DE CRECIMIENTO CELULAR y en la DIFERENCIACIÓN CELULAR al modular las interacciones ligando-receptor. (bvsalud.org)
  • Glutamate receptor 1 or GluA1/GluR1 glutamate receptor is a member of the glutamate-gated ion channel family. (antibodiesinc.com)
  • Enzymatic removal of contactin from the cell surface of cotransfected cells does not reduce the elevated levels of the Na v 1.3 current. (jneurosci.org)
  • Finally, we show that, similar to Na v 1.3, contactin is upregulated in axotomized DRG neurons and accumulates within the neuroma of transected sciatic nerve. (jneurosci.org)
  • In this study, we show that contactin associates with Na v 1.3 in P0 brain tissue and interacts with both the N and C termini of Na v 1.3. (jneurosci.org)
  • We also show that contactin is upregulated in parallel with Na v 1.3 in axotomized DRG neurons and accumulates together with Na v 1.3 at the injured axon tips within the neuroma. (jneurosci.org)
  • We show that in response to DNA damage, polyunsaturated fatty acids, especially arachidonic acid (AA) and AA-related lipid mediators, are elevated and this is dependent on mys-1 . (knoblauchpublishing.com)
  • Cell Rep. 2016 Mar 1;14(8):2017-29. (utmb.edu)
  • Burgdorf JS, Yoon S, Dos Santos M , Lammert CR, Moskal JR, Penzes P . An IGFBP2-derived peptide promotes neuroplasticity and rescues deficits in a mouse model of Phelan-McDermid syndrome. (neurotree.org)
  • Here we found that the germinal ablation of the MAPK c-Jun N-Terminal Kinase isoform 1 (JNK1) results in a significant reduction of myelin in the cerebral cortex and corpus callosum at both postnatal and adult stages. (nature.com)