Peptide 1 receptor activation glucagon receptors receptors glucagon. Medical search. Frequent questions

Within the presence of Brij micelles, the refolded receptor binds the agonist exendin-Four with an obvious dissociation fixed of roughly 100 nM in a reversible one-step mechanism. (ncbcs.org)
In an attempt to use GLP-1 responsiveness as a means to screen targets of hindbrain cells that participate in the termination of thirst and the resultant water intake, we injected the GLP-1 receptor agonist exendin-4 (Ex-4) into three brain areas known to express GLP-1 receptors, and measured subsequent water intake. (listlabs.com)
We conducted a prospective cohort study comparing the effect of pretreatment with liraglutide or vehicle on thromboxane receptor agonist-induced in vitro activation of platelets from patients with AERD and nonasthmatic controls. (bvsalud.org)
Liraglutide attenuated thromboxane receptor agonist-induced activation as measured by CXCL7 release in plasma from patients with AERD and CD62P expression in platelets from both patients with AERD (n = 31) and nonasthmatic, healthy controls (n = 11). (bvsalud.org)
Liraglutide, a Food and Drug Administration-approved GLP-1R agonist for treatment of type 2 diabetes and obesity, attenuates in vivo platelet activation in an AERD murine model and in vitro activation in human platelets in patients with and without AERD. (bvsalud.org)
Pemvidutide is a novel, investigational GLP-1/glucagon dual receptor agonist under development for the treatment of obesity and non-alcoholic steatohepatitis (NASH). (altimmune.com)
Pemvidutide is a novel, investigational, peptide-based GLP-1/glucagon dual receptor agonist in development for the treatment of obesity and NASH. (altimmune.com)
The Company's lead product candidate, pemvidutide, is a GLP-1/glucagon dual receptor agonist that is being developed for the treatment of obesity and NASH. (altimmune.com)
The Effects of NLY01, a Novel Glucagon-Like Peptide-1 Receptor Agonist, on Cuprizone-Induced Demyelination and Remyelination: Challenges and Future Perspectives. (neurotree.org)
The GLP-1 agonist Wegovy has re-energized the hunt for obesity treatments. (eusaintlaurent.de)
Glucagon-like peptide 1 (GLP-1) is a natural peptide agonist of the GLP-1 receptor (GLP-1R) found on pancreatic β-cells. (eusaintlaurent.de)

Activation stimulates insulin release from the islet β-cells in a glucose-dependent manner and suppresses glucagon secretion from islet α-cells. (tocris.com)
Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1," PNAS , 104:15069-74, 2007. (the-scientist.com)
Additionally, CGRP might be important in processes such as control of fetoplacental vascular tone, regulation of calcium metabolism and insulin secretion, acetylcholine receptor synthesis, peripheral nerve regeneration, and neurogenic inflammation. (bachem.com)
inhibitor (KN-93) abolished D3R-stimulated GLP-1 secretion. (technuc.com)
Pre-treatment of cells having a G protein-coupled receptor (GPR) 40/120 antagonist (GW1100) also considerably reduced D3R-stimulated GLP-1 secretion. (technuc.com)
These observations claim that D3R stimulates GLP-1 secretion in GLUTag cells, which activation of GLP-1 secretion by D3R is usually mediated via Ca2+-CaMKII pathway, which might possibly become mediated by GPR40/120. (technuc.com)
These results provide a feasible molecular system of GLP-1 secretion in intestinal L-cells mediated by foods or medicines and demonstrate a book natural function of anthocyanins when it comes to GLP-1 secretion. (technuc.com)
Intro Glucagon-like peptide-1 (GLP-1) secreted from enteroendocrine L-cells is usually one kind of incretin and stimulates glucose-dependent insulin secretion and proliferation of pancreatic -cells [1C3]. (technuc.com)
However, an alternative solution therapeutic approach would be to boost endogenous GLP-1 secretion through modulation from the secretory systems in intestinal L cells using pharmaceutical brokers or dietary elements. (technuc.com)
Several nutrients and little substances are reported to improve GLP-1 secretion and you need to include certain essential fatty acids [10C12], in addition to glutamine and arginine, that are well-characterized GLP-1 Freselestat manufacture secretagogues [13C15]. (technuc.com)
Proteins hydrolysates are also reported to stimulate improved GLP-1 secretion [16C19]. (technuc.com)
We previously exhibited that curcumin, a yellowish pigment isolated from turmeric, markedly raises GLP-1 secretion within the murine GLUTag cell collection [20]. (technuc.com)
Regardless of the abundant proof that several nutrition and drug applicants activate GLP-1 secretion, there's little Freselestat manufacture proof that nonnutritive meals compounds, rather than the nutrition themselves, have the ability to straight enhance GLP-1 secretion. (technuc.com)
Ligand-dependent activation of the G-protein coupled receptor 119 (GPR119) lowers blood glucose via glucose-dependent insulin secretion and intestinal glucagon-like peptide-1 production. (biomedcentral.com)
GLP-1 is an intestinally-derived peptide that stimulates insulin secretion in response to food intake, as well as reducing the rate of gastric emptying, thus promoting satiety and weight loss. (ddw-online.com)

Activation of the glucagon-like peptide-1 receptor (GLP-1R) upon ligand binding results in the discharge of insulin from pancreatic cells. (ncbcs.org)
The decrease ligand affinity of the nGLP-1R outcomes completely from a decreased kinetic stability of the receptor-ligand advanced, dissociation of which is roughly 40-fold quicker within the case of the nGLP-1R in comparison with the full-length GLP-1R. (ncbcs.org)
Vasoactive intestinal peptide (VIP) is a 28-amino acid neuropeptide which belongs to a glucagon/secretin superfamily, the ligand of class II G protein-coupled receptors. (rcsb.org)
One mechanism is the binding of an extracellular ligand to a transmembrane G-protein-coupled receptor (GPCR). (pancreapedia.org)

Results of low-dose recombinant human insulin-like development factor-I on insulin sensitivity, development hormone and glucagon ranges in younger adults with insulin-dependent diabetes mellitus. (ncbcs.org)
We've studied the results of low-dose bolus subcutaneous rhIGF-I (40 microg/kg and 20 microg/kg) on insulin sensitivity, development hormone (GH) and glucagon ranges in seven younger adults with insulin-dependent diabetes mellitus (IDDM) utilizing a randomized double-blind placebo-controlled crossover research design. (ncbcs.org)
For example, the pancreatic release of insulin in response to glucose is partially mediated by the binding of glucose to sweet-taste receptors on cells of the intestine and subsequent activation of the signaling cascade. (the-scientist.com)
Insulin, via a series of kinase activations and transductions, causes the glucose type 4 transporter channels to become embedded in the cellular membrane, allowing an exponential increase of glucose entry into the cell. (encyclopedia.pub)
T2D is characterized by failure of the insulin receptors to respond to insulin, thus preventing glucose uptake from the bloodstream. (encyclopedia.pub)
This was followed by the purification of insulin by a Canadian, Dr. Frederick Banting, and his team, with its direct administration to diabetic patients in 1921 [ 1 ] . (encyclopedia.pub)
GLP-1 has been reported to improve glucose-dependent insulin action through the G-protein-coupled receptor, GLP-1R (Drucker and Nauck, 2006). (eusaintlaurent.de)
Engagement of the receptor stimulates insulin release in a glucose-dependent fashion and increases β-cell mass, two ideal features for pharmacologic management of type 2 diabetes. (eusaintlaurent.de)
This altered glucose metabolism state is associated with an increased risk of developing T2DM (Figure 1), although other parameters including excess adiposity, inflammation and dyslipidemia are risk factors associated with the development of insulin resistance, loss of pancreatic function, worsening of hyperglycemia and progression to diabetes (1). (ddw-online.com)
The normal microbiota also converts primary bile acids to secondary bile acids, which are also anti-inflammatory, induce glucagon-like peptide 1 (which in turn increases insulin), and decrease, for example, sporulation of Clostridium difficile. (todaysveterinarypractice.com)
The pancreas lies in the curve of the duodenum and controls the level of sugar in the blood by secreting insulin and glucagon. (medscape.com)

It has been demonstrated that glucagon-like peptide-1 (GLP-1), which is an endogenous insulinotropic peptide secreted from the intestine, binds to its receptor within the mind and possesses neuroprotective results. (ncbcs.org)
Using the effective response after injection into the PVH as a guide, we examined the connection between the NTS - the site of endogenous central GLP-1 production - and the PVH. (listlabs.com)
Taken together, we conclude that the PVH is a site of action for GLP-1 receptor activation in the inhibition of water intake, but suspect that endogenous GLP-1 in NTS-to-PVH projections may be counterbalanced by a parallel pathway that either activates or maintains already activated water intake. (listlabs.com)
Two endogenous circulating forms, PYY 1-36 and PYY 3-36 , are synthesized within the gut. (hindawi.com)

In addition to the metabolic effects in diabetes, glucagon-like peptide 1 receptor (GLP-1R) agonists lead to a small but substantial increase in heart rate (HR). However, the GLP-1R actions on the autonomic nervous system (ANS) in diabetes remain debated. (e-dmj.org)
Glucagon-like peptide 1 receptor (GLP-1R) agonists represent a relatively new class of anti-hyperglycemic agents, addressing most of the pathophysiological mechanisms involved in the development of T2DM. (e-dmj.org)
We hypothesized that GLP-1R agonists reduce platelet activation and downstream platelet-mediated airway inflammation in AERD. (bvsalud.org)
The GLP-1 receptor agonists currently approved in the United States for the treatment of type 2 diabetes include exenatide (administered twice daily), liraglutide and lixisenatide (administered once daily), and the once-weekly agents exenatide extended-release, albiglutide, and dulaglutide. (eusaintlaurent.de)
casino 3f.com mandt bank near me hours The GLP-1 receptor agonists currently approved in the United States for the treatment of type 2 diabetes include exenatide (administered twice daily), liraglutide and lixisenatide (administered once daily), and the once-weekly agents exenatide extended-release, albiglutide, and dulaglutide. (eusaintlaurent.de)

G protein-coupled receptors (GPCRs) belong to the largest class of drug targets. (mdpi.com)
Lipid-sensing G-protein-coupled receptors (GPCRs) are highly expressed in pancreatic β-cells and implicated with metabolic symdroms [ 9 ]. (biomedcentral.com)

Approximately half of the members of the human GPCR superfamily are chemosensory receptors, including odorant receptors (ORs), trace amine-associated receptors (TAARs), bitter taste receptors (TAS2Rs), sweet and umami taste receptors (TAS1Rs). (mdpi.com)
Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells," PNAS , 99:2392-97, 2002. (the-scientist.com)

Measurement of cAMP levels in isolated rat small intestinal mucosal cells expressing GLP-2 receptors. (guidetopharmacology.org)
B) In a diseased state, regardless of the initiating cause, the decreased production of antimicrobial peptides and mucus leads to increased intestinal permeability and translocation of bacteria. (todaysveterinarypractice.com)

Glucagon-like peptide 1 (GLP-1) receptors are members of the glucagon receptor family that also includes glucagon , GLP-2 , secretin , GHRH and GIP receptors. (tocris.com)
In micelle-bound PACAP-38 (one of the glucagon/secretin superfamily peptide) structure, the identical hydrophobic residues form the micelle-binding interface. (rcsb.org)

Despite the difference in the qualities detected by the two families of taste receptors, both utilize similar, if not identical, downstream signaling effectors, including the taste receptor-associated G protein a-gustducin, one of the first identified proteins of a GPCR taste transduction cascade. (the-scientist.com)
Recent studies have shown that the previously cloned G protein-coupled orphan receptor, named calcitonin receptor-like receptor (CRLR), can interact with members of a new family of three single-transmembrane domain receptor activity-modifying proteins (RAMPs). (bachem.com)
The molecular system underlying this impact can be described by the activation of AMP-activated proteins kinase [25, 26]. (technuc.com)

4 In the ARC, there are two distinct neuronal populations: one group of neurons produces the orexigenic neuropeptides neuropeptide Y (NPY) and agouti-related peptide (AgRP), whereas the other subset of neurons expresses the anorexigenic neuropeptides proopiomelanocortin (POMC), and cocaine- and amphetamine-regulated transcript. (nature.com)
The PP-fold family comprises neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP). They are composed of a chain of 36 amino acids residue and share amino acid homology, amidated C-terminal ends. (hindawi.com)

Innate immune receptors, such as Toll-like receptors on macrophages and other immune cells, recognize specific pathogen-associated molecular patterns due to dysbiosis (eg, lipopolysaccharides in bacterial cell walls) and trigger inflammatory reactions. (todaysveterinarypractice.com)

This strictly glucose-dependent course of renders the receptor and its ligands helpful within the remedy of sort II diabetes mellitus. (ncbcs.org)

Based on early pharmacological studies, the existence of two classes, CGRP1 and CGRP2 receptors, has been described. (bachem.com)
lee women Background: The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad pharmacological potential. (eusaintlaurent.de)

In addition, GLP-1 receptors delay gastric emptying and regulate appetite. (tocris.com)
Compounds we perceive as sweet or bitter in the mouth trigger similar receptors and signaling pathways elsewhere in the body, helping to regulate digestion, respiration, and other systems. (the-scientist.com)

Jun 29, 2022 · Weight loss can vary depending on which GLP-1 drug you use and your dose. (eusaintlaurent.de)

A single dose of liraglutide inhibited Lys-ASA-induced increases in airway resistance and decreased markers of platelet activation and recruitment to the lung in AERD-like mice. (bvsalud.org)
Studies have found that all GLP-1 drugs can lead to weight loss of about 10.5 to 15.8 pounds (4.8 to 7.2 kilograms, or kg) when using liraglutide. (eusaintlaurent.de)

At their N-terminus, these peptides have in common a characteristic disulfide loop structure, generally formed by six to seven amino acids. (bachem.com)

Peripheral or central GLP-1 suppresses food intake and reduces body weight. (eusaintlaurent.de)

Glucagon-like peptide-1 ( GLP-1) is a 30- or 31-amino-acid-long peptide hormone deriving from the tissue-specific posttranslational processing of the proglucagon peptide. (eusaintlaurent.de)

Our Peptides Involved in Appetite Modulation review gives an overview of the peptides implicated in appetite regulation and energy homeostasis. (tocris.com)
Furthermore, Abeta(1-42) remedy dramatically stimulated the discharge of Ca(2+) from inside calcium shops in SH-SY5Y cells, whereas mGLP-1 helped to take care of the intracellular Ca(2+) homeostasis. (ncbcs.org)
The ability of all mammals to cope with any environmental or homeostatic challenge (i.e., stressor), or with perceptual threats to homeostasis, relies upon activation of a neuroendocrine signaling cascade called the hypothalamic-pituitary-adrenal (HPA) axis. (nature.com)
Because of its founded role within the metabolic response, especially blood sugar homeostasis, GLP-1 can be an essential aspect in the procedure and avoidance of type 2 diabetes. (technuc.com)

Jun 4, 2023 · The GLP-1 medications used in the Calibrate program help your body to fight the natural increases in appetite and hunger hormones that occur as you begin to lose weight. (eusaintlaurent.de)

5 The anorexigenic effect of monoamine serotonin is also mediated by the 5HT-2C receptor in POMC neurons. (nature.com)
of serotonin receptor function and serotonin-dopamine interactions. (web.app)
It's for this reason that Ibogaine (and its effects on dopamine and serotonin receptors in the brain) works so well to help people looking to defeat their addictive tendencies. (web.app)

The human GLP-1 receptor gene is localized on chromosome 6p21. (tocris.com)
Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-beta peptide (1-42). (ncbcs.org)
Utilizing site-directed mutagenesis and gene recombination strategies, we generated a mutated recombinant human glucagon-like peptide-1 (mGLP-1) which has longer half-life as in contrast with native GLP-1. (ncbcs.org)
Recombinant expression, in vitro refolding, and biophysical characterization of the human glucagon -like peptide-1 receptor. (ncbcs.org)
Human platelets express the glucagon-like peptide-1 receptor (GLP-1R). (bvsalud.org)
Expression of functional cysteinyl leukotriene receptors by human basophils. (cictrials.ca)
According to this historical classification CGRP1 receptors are more sensitive to the antagonistic properties of α-CGRP (8-37) ( 4013696 , 4034544 ) whereas CGRP2 receptors are more responsive to the agonistic CGRP analogs, (Cys(Acm) 2,7 -α-CGRP (human) ( 4039880 ) and (Cys(Et) 2,7 )-α-CGRP (human) ( 4039888 ). (bachem.com)
1 Additionally, initial data in human and animal models have linked chronic dysbiosis, such as that caused by antibiotic exposure, to extraintestinal disorders such as diabetes and obesity. (todaysveterinarypractice.com)
In a healthy symbi- posed of about as many microorgan- after the pioneering work of Gordon otic state, the colonic microbiota isms as there are cel s in the human and collaborators [1]. (who.int)

The amino acid sequences of CGRP peptides are well conserved among species, as illustrated in Scheme 1. (bachem.com)
In dogs, pigs and numerous other species, variants of the CGRP-like calcitonin receptor-stimulating peptide (CRSP) are expressed in place of β-CGRP. (bachem.com)

In the last 15 years, researchers have uncovered more and more taste cascade elements throughout the digestive tract, and even in the airways, suggesting a widespread distribution of complete taste transduction cascades-from taste receptor to transduction channel. (the-scientist.com)
Similarly, accidental inhalation of a beverage into the airways triggers taste receptors there, but rather than evoking a sensation of taste, the substance is irritating and provokes choking or coughing. (the-scientist.com)

Over the last two decades, as scientists have uncovered the array of G protein-coupled receptor (GPCR) cascades and ion channels that underlie taste signaling, they have also discovered, to their surprise, that the expression of these receptors and channels is not limited to taste buds. (the-scientist.com)
Anatomical profiling of G protein-coupled receptor expression. (guidetopharmacology.org)
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). (web.app)
The receptor protein has seven transmembrane α-helices connected by alternating cytosolic and extracellular loops. (pancreapedia.org)
The quantitative protein excretion is less than 1 g/day. (medscape.com)

The World Health Organization (WHO) defines obesity as an abnormal fat accumulation that may impair health ( 1 ). (frontiersin.org)
Despite recent progress in our understanding of the physiological mechanisms regulating body weight and energy expenditure, obesity remains a major worldwide health crisis with an array of vascular, metabolic, and psychosocial consequences [ 1 , 2 ]. (hindawi.com)

Based on morphological features, researchers had suspected that these cells were chemosensory, but the findings of gustducin, taste receptors,[2. (the-scientist.com)
TRPM5, a taste-signaling transient receptor potential ion-channel, is a ubiquitous signaling component in chemosensory cells," BMC Neurosci , 8:49, 2007. (the-scientist.com)

Interestingly, activation of this population of cells increased water intake, calling into question the heterogeneity of the pathway with respect to the control of fluid intake. (listlabs.com)

Genetic inactivation of dopamine D1 or D2 receptors protects against the loss of dopa-minergic ﬁbres in the striatum and loss of dopa-minergic neurons in the substantia nigra. (web.app)

Accumulation and deposition of amyloid beta peptide (Abeta) within the mind causes neuronal apoptosis and finally results in Alzheimer's illness (AD). (ncbcs.org)
These outcomes recommend that mGLP-1 exhibited neuronal safety properties, and will probably be a novel therapeutic agent for intervention in Alzheimer's illness. (ncbcs.org)
Specialized neuronal networks in the brain coordinate adaptive changes in food intake and energy expenditure in response to altered metabolic conditions ( Figure 1 ). (nature.com)

Activation of the GLP-1 and glucagon receptors is believed to mimic the complementary effects of diet and exercise on weight loss, with GLP-1 suppressing appetite and glucagon increasing energy expenditure. (altimmune.com)

Long-term neurologic sequelae (varying degrees of irreversible brain injury) may produce a thermogenic effect by activation of dopamine receptors and by av L Goñi-Mateos · 2017 - dopamine receptor D2 (DRD2) genes, with weight loss after different behavioral interventions has been reported (217,218). (web.app)

putative roles of the major peptides are outlined and compounds available from Tocris are listed. (tocris.com)

Le tissu adipeux sécrète, en effet, une grande variété de molécules biologiquement actives agissant pour prévenir l'accumulation délétère de lipides et la modulation de l'insulinorésistance. (erudit.org)

GLP-1 is involved in the regulation of energy balance (Holst, 2007), and its activation and subsequent binding to the GLP-1R reduces food intake and, consequently, body weight (Turton et al. (eusaintlaurent.de)

Measurement of the activity of a cAMP-dependent reporter gene, CRE-β-galactosidase, in BHK cells endogenously expressing the GLP-2 receptor. (guidetopharmacology.org)
As circulating GLP-1 is usually rapidly inactivated from the enzyme dipeptidyl peptidase IV (DPP-4) through cleavage from the N-terminal area of undamaged GLP-1 [6, 7], DPP-4 inhibitors are encouraging therapeutic brokers for increasing the half-life of endogenously secreted GLP-1. (technuc.com)

1 The brain monitors changes in the body energy state by sensing alterations in the plasma levels of key metabolic hormones and nutrients. (nature.com)
av AL Hollis · 2006 - brain scanning, did not definitively back up a link between brain damage and encode or serve as the blueprint for dopamine receptors and are highly active in neurological patients with amygdala damage are unable to recognize fearful facial Dopamine Receptors in Vicarious Pain: A Combined Pet-Fmri Study. (web.app)

More recent incretin-based treatment strategies include glucagon-like peptide-1 (GLP-1) mimetics and inhibitors of the enzyme that degrades GLP-1, dipeptidyl peptidase-4 (DPP-4). (ddw-online.com)

The diabetic autonomic neuropathy is defined as a heterogeneous category of disorders of the autonomic nervous system (ANS) in individuals with either diabetes mellitus or metabolic derangements of pre-diabetes, when other potential causes have been excluded [ 1 ]. (e-dmj.org)
Conversely, changes in the intricate relationship between gut bacteria and host cells affect the host's immune responses and metabolic status and may result in disease ( Figure 1 ). (todaysveterinarypractice.com)

Previous studies examined the diverse functions of lipid-sensing receptors in the development and progression of cancer. (biomedcentral.com)

1996).The glucagon-like peptide-1 (GLP-1) plays important roles in the regulation of food intake and energy metabolism. (eusaintlaurent.de)
orlando premium outlets review 04 hex to binary Dec 17, 2021 · The glucagon-like peptide-1 (GLP-1) plays important roles in the regulation of food intake and energy metabolism. (eusaintlaurent.de)

GLP-1 receptors mediate the effects of the incretin axis. (tocris.com)
Glucagon is also recognized as having direct effects on hepatic fat metabolism, leading to rapid reductions in levels of liver fat. (altimmune.com)
In addition to its proinsulinemic effects, GLP-1 has been shown to have extrapancreatic effects when administered systemically. (eusaintlaurent.de)
Despite a certain number of gastrointestinal side-effects, the GLP-1 mimetic exenatide was approved by the FDA in 2005, and its indication was extended in 2009 to standalone therapy for T2DM. (ddw-online.com)

An understanding of how these circuits interact, and their roles in the activation, maintenance, and termination of fluid intake remains incomplete. (listlabs.com)
Imaging studies have provided new insights on the role of dopamine (DA) in drug Moreover, the reductions in D2 DA receptors in the striatum are associated DA in the loss of control and compulsive drug intake that characterizes add Gerfen CR , Engber TM , Mahan LC , et al: D1 and D2 dopamine receptor- regulated gene expression in striatonigral and striatopallidal neurons. (web.app)

Many therapeutic methods to enhance GLP-1 actions are being analyzed and include the usage of GLP-1 analogs, which improve glycemic control in type 2 diabetes individuals [4, 5]. (technuc.com)
Nevertheless, GLP-1 analogs aren't suitable for dental administration and should be hypodermically injected. (technuc.com)

[ 1 ] Reducing proteinuria in such cases has a protective effect against further loss of kidney function. (medscape.com)

The 37 amino acid peptides α-CGRP and β-CGRP are encoded by different genes on chromosome 11. (bachem.com)

or = 0.02 ng/ml of mGLP-1 facilitated cell proliferation and 0.1 ng/ml and 0.5 ng/ml of mGLP-1 rescued SH-SY5Y cells from Abeta(1-42)-induced apoptosis. (ncbcs.org)
In this study we have assessed the role of DA D1 and D2 receptors (D1R and D2R) on striatal METH-induced apoptosis and depletion of DA-terminal markers. (web.app)

Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin," PNAS , 93:6631-34, 1996. (the-scientist.com)
Expression of activation markers in circulating basophils and the relationship to allergen-induced bronchoconstriction in subjects with mild allergic asthma. (cictrials.ca)
Measurement of cAMP levels in the stable GLP-2 receptor episomal expression line, rG2R. (guidetopharmacology.org)

Anatomy9

Organisms4

Diseases1

Chemicals and Drugs29

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Phenomena and Processes12

Information Science2

Agonist11

Secretion15

Ligand4

Insulin11

Endogenous4

Agonists5

GPCRs2

Bitter taste receptors2

Intestinal2

Secretin2

Proteins3

Neuropeptide2

Immune receptors1

Ligands1

Pharmacological2

Regulate2

20221

Liraglutide2

Amino acids1

Suppresses1

Hormone1

Homeostasis4

20231

Serotonin3

Human9

Species2

Airways2

Protein5

Obesity2

Chemosensory2

Interestingly1

Protects1

Neuronal3

Appetite1

Behavioral1

Compounds1

Modulation1

Subsequent1

Endogenously2

Brain2

Inhibitors1

Metabolic2

Progression1

Food intake2

Effects4

Intake2

Analogs2

Function1

Genes1

Apoptosis2

Expression3