• Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptides. (ouhsc.edu)
  • Salkinoja-Salonen says her team coined the term "trilongins" ("trilong-" is from " Trichoderma longibrachiatum ," and "-in" is the suffix for any peptaibol toxin) for the specific sets of peptaibols they identified to distinguish the unique group effect from that of single peptaibols. (nih.gov)
  • Are the ants detecting the peptaibols produced by the invading Trichoderma, triggering a weeding response? (earth.com)
  • Trichoderma longibrachiatum produces many secondary metabolites including: peptaibols, polyketides, pyrones, terpenes and diketopiperazine-like compounds. (nutrawiki.org)
  • Peptaibols are secondary metabolites formed by certain fungi that have been generally known for many years to alter ion channels in membranes. (nih.gov)
  • They discovered that ants identify diseased fungus by sniffing out specific chemicals named peptaibols. (earth.com)
  • Maybe the fungus is detecting the peptaibols. (earth.com)
  • Further investigation by the team revealed that the substances involved in the ion channel damage contained various mixtures of two size classes of peptaibols-one 11-residue peptaibol and eight 20-residue peptaibols. (nih.gov)
  • Despite this breakthrough, the team faced the daunting challenge of identifying the specific peptaibols responsible for triggering the ants' weeding activity . (earth.com)
  • The team discovered that the peptaibols acted synergistically, with greater damage caused by isolates in which the two classes were combined. (nih.gov)