• Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). (drugbank.com)
  • Sodium stibogluconate , sold under the brand name Pentostam among others, is a medication used to treat leishmaniasis . (mdwiki.org)
  • Sodium stibogluconate is available in the United Kingdom as Pentostam, where it is manufactured by GlaxoSmithKline . (mdwiki.org)
  • Fifty two patients had receivedmeglumine antimoniate (glucantime) and 18 received sodium stibogluconate (pentostam) alongwith supportive therapy. (edu.pk)
  • The basic treatment consists in the administration of sodium stibogluconate (Pentostam) meglumine (Glucantime) pentamidine or amphotericin B. Treatment failure especially for kala-azar mucosal leishmaniasis and diffuse cutaneous leishmaniasis is becoming a common problem in many areas where leishmaniasis is usually endemic. (brain-tumor-cancer-information.com)
  • These findings could help to confirm and advance the understanding of a role of Leishmania AQP1 in the sensitivity and resistance to first-line antimonial drugs such as Glucantime and Pentostam. (gla.ac.uk)
  • Only a limited number of drugs are readily available for the treatment of leishmaniasis such as pentamidine, amphotericin B, pentostam, paromomycin, and miltefosine, none of which is reported free from associated drug adverse effects, low efficacies, high cost, etc. (springeropen.com)
  • Amphotericin B and Pentostam were used as standard drugs in in vitro evaluation of anti-leishmania activity. (ac.ke)
  • Antiparasitic pentavalent antimonials, such as sodium stibogluconate (Pentostam) or meglumine antimonate, have been the mainstays of therapy for all forms of the disease. (medscape.com)
  • Pentavalent antimonials (Sb(V)) such as meglumine antimoniate (Glucantime®) and sodium stibogluconate (Pentostam®) are used as first-line treatments for leishmaniasis, either alone or in combination with second-line drugs such as amphotericin B (Amp B), miltefosine (MIL), methotrexate (MTX), or cryotherapy. (nih.gov)
  • On the other hand, L brasiliensis causes mucocutaneous leishmaniasis, a more severe form encountered in Peru, which has traditionally been treated with an antimonial antibiotic called Pentostam, known for its side effects. (newsreaders.info)
  • Strains from Sb 5 -treated patients with American cutaneous and mucocutaneous disease who fail at least one complete course of Pentostam are as highly nonresponsive to this drug as laboratory-proven drug-resistant Leishmania strains. (ajtmh.org)