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  • biosynthesis
  • 2. Veiga T., Gombert A.K., Landes N., Verhoeven M.D., Kiel J.A., Krikken A.M., Nijland J.G., Touw H., Luttik M.A., Van der Toorn J.C. and Driessen A.J. Metabolic engineering of β-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis. (ac.ir)
  • genome
  • In silico analysis of the P. chrysogenum genome revealed the presence of a gene, Pc13g09140, initially described as paralogue of the IAT-encoding penDE gene. (beds.ac.uk)
  • pcbC
  • qPCR analysis of mRNAs extracted from P. chrysogenum indicated that the expression levels of pcbAB, pcbC increased in seven days after inoculation compared to the expressed levels with others time courses, but this difference was not significant statistically. (ac.ir)
  • genus
  • Although blue-green molds of the genus Penicillium are ubiquitous in the human environment, invasive penicilliosis is uncommon and primarily encountered among immunosuppressed patients. (springer.com)
  • As John Pitt wrote in 1979, "Rare indeed must be the human individual who has not encountered fungi of the genus Penicillium or been affected by one of the many metabolites [compounds] produced by them. (robdunnlab.com)
  • The genus Penicillium , by John I. Pitt. (robdunnlab.com)
  • nidulans
  • Sequence comparison among the P. chrysogenum IAL, the A. nidulans IAL homologue and the IAT, revealed that the lack of enzyme activity seems to be due to an alteration of the essential Ser309 in the thioesterase active site. (beds.ac.uk)
  • compounds
  • In order to discover novel active antimetastatic and antiangiogenic compounds, secondary metabolites of halotolerant Penicillium chrysogenum -1(hPc-1) isolated from Tuz Lake in Turkey and ethylacetate extract of hPc-1 was prepared from the isolate of hPc-1 culture medium. (ijpsonline.com)
  • Here, we show that deletion of the highly expressed nonribosomal peptide synthetase (NRPS) gene Pc21g12630 (chyA) resulted in a decrease in the production of chrysogine and 13 related compounds in the culture broth of P. chrysogenum. (chalmers.se)
  • metabolic
  • The review of different proteomics methods applied to P. chrysogenum has revealed that industrial modification of this microorganism was a consequence of a careful rebalancing of several metabolic pathways. (hindawi.com)
  • role
  • The principal role of P. chrysogenum in nature is to break down organic material, to decompose products into their basic elements. (robdunnlab.com)
  • study
  • T=1 capsids of Penicillium chrysogenum virus (PcV) (this study), L-A virus, rotavirus, bluetongue virus (BTV), rice dwarf virus (RDV), orthoreovirus, cytoplasmic polyhedrosis virus (CPV), Penicillium stoloniferum virus F (PsV-F), picobirnavirus (PBV), and φ6 phage are viewed along a 2-fold axis of icosahedral symmetry (center row). (nih.gov)
  • patient
  • A patient with HIV infection who died of severe necrotizing esophagitis caused by Penicillium chrysogenum is reported and the relevant English language literature on human penicilliosis is reviewed. (springer.com)
  • Systemic infection caused by Penicillium decumbens in a patient with acquired immunodeficiency syndrome. (springer.com)
  • means
  • Penicillus means "little brush" in Latin, and if Penicillium is a paintbrush, then the world is its canvas. (robdunnlab.com)
  • Penicillium chrysogenum converts isopenicillin N (IPN) into hydrophobic penicillins by means of the peroxisomal IPN acyltransferase (IAT), which is encoded by the penDE gene. (beds.ac.uk)