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Sentinel Lymph Node BiopsyLymph Node ExcisionLymph NodesVulvar NeoplasmsPelvisLymphatic MetastasisEndometrial NeoplasmsHysterectomyAxillaRosaniline DyesTechnetium Tc 99m Sulfur ColloidNeoplasm StagingLymphoceleLymphoscintigraphyTechnetium CompoundsMelanomaCystectomySkin NeoplasmsUterine Cervical NeoplasmsBreast NeoplasmsFrozen SectionsFalse Negative ReactionsRetroperitoneal SpaceColoring AgentsPrognosisInguinal CanalIntraoperative PeriodTechnetium Tc 99m Aggregated AlbuminAdenocarcinomaLaparoscopyNeoplasm Recurrence, LocalLymphNeoplasm MicrometastasisRetrospective StudiesSentinel SurveillanceLymphographyPenile NeoplasmsCarcinoma, EndometrioidIntraoperative CareSensitivity and SpecificityRadiopharmaceuticalsCarcinoma, Squamous CellIndocyanine GreenGamma CamerasCarcinoma, LobularUrinary Bladder NeoplasmsMethylene BlueCarcinoma, Ductal, BreastHematoxylinTreatment OutcomeNeoplasm InvasivenessImmunohistochemistrySpectroscopy, Near-InfraredProstatic NeoplasmsGastrectomyProstatectomyProspective StudiesTin CompoundsCarcinomaGroinRectal NeoplasmsPredictive Value of TestsLymphedemaVideo-Assisted SurgeryStomach NeoplasmsEosine Yellowish-(YS)Survival RateFollow-Up StudiesTumor Markers, BiologicalFeasibility StudiesMastectomyNomogramsCytodiagnosisDisease-Free SurvivalLymphatic VesselsSurvival AnalysisLymphangiogenesisLymphatic SystemNeoplasm MetastasisKeratinsChemotherapy, AdjuvantNeck DissectionKeratin-19Radiotherapy, AdjuvantOptical ImagingReproducibility of ResultsPreoperative CareNipplesSeromaRisk FactorsPancreatic NeoplasmsColloidsEsophageal NeoplasmsBiopsyOvarian NeoplasmsKaplan-Meier EstimateCarcinoma, Intraductal, NoninfiltratingBiopsy, NeedleQuantum DotsMediastinum
BiopsyCarcinomaDissectionUnderwent2023Vaginal CancerUterine CancerProcedureUterusMalignantCervixGynecologicMassPatient educationVulvaAffectsPracticeWomenTreatmentPositiveCasesCareTopicCommonMelanomaBiopsyMetastasisIncidenceDiseaseCervical cancerChemotherapyRecurrent ovarian cancerBladderMorbidityDetectionSurgicalIntermediateImagingFrequencyDistantCommonlyCervixEvidenceRegionsPrimaryInstituteCareHighResult
Biopsy10
  • Experts in endometrial cancer suggest there should be a change in the standard of care, after the largest study to date found that sentinel lymph node biopsy is as accurate for identifying metastasis as complete pelvic lymphadenectomy, which is more invasive and is the current gold standard. (medscape.com)
  • The findings come from the FIRES study (Fluorescence Imaging for Robotic and Endometrial Sentinal Lymph Node Biopsy), which was published online on January 31 in Lancet Oncology . (medscape.com)
  • The study found that sentinel lymph node biopsy accurately ruled out metastasis in more than 99% of cases. (medscape.com)
  • The false negative rate was 3%, similar to that for cases of breast cancer, melanoma, and vulvar cancer, for which sentinel-lymph node biopsy has become the standard of care. (medscape.com)
  • I think sentinel lymph node biopsy can replace the traditional lymphadenectomy technique and should become the standard of care in endometrial cancer. (medscape.com)
  • Sentinel lymph node biopsy involves removal only of organ-specific lymph nodes, identified by injecting dye near the primary tumor. (medscape.com)
  • Currently, the National Comprehensive Cancer Network endorses sentinel lymph node biopsy as an acceptable standard of care for surgical staging of endometrial cancer in select patients. (medscape.com)
  • OBJECTIVES: To evaluate the prevalence of post-operative complications and quality of life (QoL) related to sentinel lymph node (SLN) biopsy vs systematic lymphadenectomy in endometrial cancer. (bvsalud.org)
  • METHODS: A prospective cohort included women with early-stage endometrial carcinoma who underwent lymph node staging, grouped as follows: SLN group (sentinel lymph node only) and SLN+LND group (sentinel lymph node biopsy with addition of systematic lymphadenectomy). (bvsalud.org)
  • What Does the Pathologist Exactly Need From the Surgeon When Carrying Out a Lymph Node Biopsy? (bccancer.bc.ca)
Carcinoma1
Dissection2
  • Hence, it is associated with less harm and is less costly than full lymph node dissection, the researchers point out. (medscape.com)
  • That event concerned ureteral injury during sentinel lymph node dissection and did not result in long-term injury. (medscape.com)
Underwent1
  • They also underwent full pelvic lymphadenectomy and para-aortic lymphadectomy (when technically feasible and clinically relevant). (medscape.com)
20231
  • Authors Keywords: FIGO 2023 endometrial cancer staging Abstract Endometrial cancer incidence is rapidly rising global. (cn1699.cn)
Vaginal Cancer3
  • The importance of this definition lies in the different clinical approaches to the treatment of upper and lower vaginal cancer. (medscape.com)
  • As more women survive past age 60 years, physicians need to consider the likelihood that more women will present with vaginal cancer. (medscape.com)
  • Because the 5-year survival rate of treated early-stage vaginal cancer is significantly higher than that of vaginal cancer in the advanced stages, early detection is key to improving treatment outcomes. (medscape.com)
Uterine Cancer1
Procedure3
  • The traditional procedure would have missed these lymph nodes, the researchers note. (medscape.com)
  • Although lymphadenectomy helps define the risk for recurrence and enables surgical staging to guide treatment decisions, the procedure carries the risk for surgical harm and lymphedema. (medscape.com)
  • T]he sentinel-lymph-node mapping procedure is the best intermediate between complete versus no lymphadenectomy. (medscape.com)
Uterus2
  • It ranks fifth in frequency behind cancer of the uterus, cervix, ovary, and vulva. (medscape.com)
  • The uterus is centered within the broad ligament and is attached to the round ligaments, which run anterolaterally within the broad ligament from the uterus to the pelvic wall. (medscape.com)
Malignant1
  • Malignant diseases of the vagina are either primary vaginal cancers or metastatic cancers from adjacent or distant organs. (medscape.com)
Cervix1
Gynecologic1
  • Endometrial cancer is the most commonly diagnosed gynecologic cancer in the United States, affecting about 54,000 women each year. (medscape.com)
Mass1
  • Herein, we report the case of a 43-year-old woman presenting with vaginal bleeding and pelvic mass. (bvsalud.org)
Patient education1
  • For patient education information, see the Cancer Center and the Women's Health Center , as well as Vaginal Bleeding , Colposcopy , Cervical Cancer , and Bladder Control Problems . (medscape.com)
Vulva2
  • Primary vaginal cancers are defined as arising solely from the vagina, with no involvement of the external cervical os proximally or the vulva distally. (medscape.com)
  • a tumor involving both the vulva and the vagina should be considered vulvar cancer. (medscape.com)
Affects2
  • Authors Keywords: cervical cancer, treatment outcomes, young women Abstract Background: Cervical cancer affects mostl. (cn1699.cn)
  • Endometrial cancer affects mainly postmenopausal women. (msdmanuals.com)
Practice2
  • Based on these implications, sentinel-lymph-node mapping should be implemented in routine practice," they write. (medscape.com)
  • The BC Cancer Surgery Network is committed to continuous practice improvement through educational activities and events. (bccancer.bc.ca)
Women3
  • The FIRES trial was conducted in women with early endometrial cancer who were without evidence of metastasis on physical and radiologic examination. (medscape.com)
  • Authors Keywords: macroscopic cervical cancer, antiretroviral therapy, WLWH Abstract Background: Women living with HI. (cn1699.cn)
  • In the United States, this cancer is the 4th most common cancer among women. (msdmanuals.com)
Treatment2
  • Writing in a linked editorial , Frédéric Amant, MD, PhD, and Hans Trum, MD, both of the Netherlands Cancer Institute, in Amsterdam, agree that pelvic sentinel lymph node mapping is "probably sufficient to direct further treatment" and that the technique may change existing treatment protocols. (medscape.com)
  • The patients had at least 12 months of follow-up, and QoL was assessed by European Organization for Research and Treatment of Cervical Cancer Quality of Life Questionnaire 30 (EORTC-QLQ-C30) and EORTC-QLQ-Cx24. (bvsalud.org)
Positive1
  • Moreover, 17% of positive sentinel lymph nodes were identified outside regions traditionally included in complete lymphadenectomy. (medscape.com)
Cases1
  • In 1946, Alexander Brunschwig published the first cases of pelvic exenteration . (medscape.com)
Care1
  • Each year the Network develops, organizes and hosts a medical education program profiling a specific area of cancer surgery and care. (bccancer.bc.ca)
Topic1
  • This year's focus was on colorectal cancers and featured guest speakers and topic specialists. (bccancer.bc.ca)
Common1
  • Endometrial cancer is more common in high-resource countries where obesity rates are high. (msdmanuals.com)
Melanoma2
Biopsy9
  • Experts in endometrial cancer suggest there should be a change in the standard of care, after the largest study to date found that sentinel lymph node biopsy is as accurate for identifying metastasis as complete pelvic lymphadenectomy, which is more invasive and is the current gold standard. (medscape.com)
  • The findings come from the FIRES study (Fluorescence Imaging for Robotic and Endometrial Sentinal Lymph Node Biopsy), which was published online on January 31 in Lancet Oncology . (medscape.com)
  • The study found that sentinel lymph node biopsy accurately ruled out metastasis in more than 99% of cases. (medscape.com)
  • I think sentinel lymph node biopsy can replace the traditional lymphadenectomy technique and should become the standard of care in endometrial cancer. (medscape.com)
  • Sentinel lymph node biopsy involves removal only of organ-specific lymph nodes, identified by injecting dye near the primary tumor. (medscape.com)
  • Currently, the National Comprehensive Cancer Network endorses sentinel lymph node biopsy as an acceptable standard of care for surgical staging of endometrial cancer in select patients. (medscape.com)
  • Herein, 649 patients with early-stage breast cancer (cT1-T2) who received SLN biopsy were assigned to the training cohort (n = 487) and the validation cohort (n = 162). (bvsalud.org)
  • PURPOSE: To determine whether the absence of post-treatment changes in the negative sentinel lymph nodes (SLN) in the neoadjuvant setting for biopsy-proven cN + disease results in an increased regional recurrence (RR) rate in patients after SLN biopsy (SLNB) only. (bvsalud.org)
  • CONCLUSION: Absent post-treatment changes in negative SLNs for biopsy-proven cN + disease that covert to node-negative after NAST did not result in increased regional recurrence rates in our cohort. (bvsalud.org)
Metastasis8
  • The FIRES trial was conducted in women with early endometrial cancer who were without evidence of metastasis on physical and radiologic examination. (medscape.com)
  • Sentinel lymph node (SLN) status is closely related to axillary lymph node metastasis in breast cancer. (bvsalud.org)
  • This study aimed to develop a model to predict the risk of axillary SLN metastasis in early-stage breast cancer based on mammography, a noninvasive, cost-effective, and potential complementary way. (bvsalud.org)
  • These findings suggest that our prediction model based on mammography characteristics is a reliable tool for predicting SLN metastasis in patients with early-stage breast cancer. (bvsalud.org)
  • Sentinel lymph node (SLN) metastasis is an important promoter of distant metastasis in breast cancer. (bvsalud.org)
  • Here, we report a melittin-loaded and hyaluronic acid (HA)-conjugated high-density lipoprotein (HDL) mimic phospholipid scaffold nanoparticle (MLT-HA-HPPS), which dually-target to both breast cancer and its SLN and efficiently inhibit SLN metastasis in the LN metastasis model. (bvsalud.org)
  • This image of the mid abdomen shows borderline enlarged lymph node in the left para-aortic region, presumably secondary to metastasis, which is consistent with stage IVB disease. (medscape.com)
  • Furthermore, US is not suited for staging of the full extent of the tumor spread because of the inability of this technique to adequately depict all the potential sites of metastasis or the anatomic regions that contain lymph nodes. (medscape.com)
Incidence2
  • Despite their high incidence, treatment and management of these cancers remain controversial, with conflicting evidence about many aspects of the disease. (nshealth.ca)
  • [ 4 ] However, invasive cervical cancer remains a disease of significant morbidity, and it is a major cause of cancer deaths in women worldwide, although the incidence and mortality rates of invasive cervical cancer have declined substantially (particularly in countries that have well-developed screening programs). (medscape.com)
Disease1
  • Cancer of the uterine cervix (cervical cancer) is largely a preventable disease that is characterized by a long lead time. (medscape.com)
Cervical cancer4
  • risk cervical cancer patients - Subanalyses of the SCCAN study. (baskenthastaneleri.com)
  • In June 2006, the Advisory Committee on Immunization Practices (ACIP) voted to recommend the first vaccine developed to prevent cervical cancer and other diseases caused by HPV type 6, 11, 16, and 18. (medscape.com)
  • For patient education information, see the Cancer Center and the Women's Health Center, as well as Vaginal Bleeding, Colposcopy, Cervical Cancer, and Bladder Control Problems. (medscape.com)
  • [ 10 , 11 ] First intercourse at an early age, sexual promiscuity, high parity, race, and low socioeconomic status are thought to increase the risk for cervical cancer because these factors are linked to sexual behavior that increases the likelihood of exposure to HPV and/or because they are cofactors that modify the risk in women who are infected with HPV. (medscape.com)
Chemotherapy1
Recurrent ovarian cancer1
  • Recurrent Ovarian Cancer: When to Treat and How to Assess -- 3. (nshealth.ca)
Bladder1
  • The vagina is located in the true pelvis, which also contains the rest of the internal genital tract, the rectosigmoid, the bladder, the proximal urethra, and the pelvic portions of the ureters. (medscape.com)
Morbidity1
  • The sentinel lymph node technique gives more information but with less morbidity," Dr Rossi emphasized. (medscape.com)
Detection2
  • Because the 5-year survival rate of treated early-stage vaginal cancer is significantly higher than that of vaginal cancer in the advanced stages, early detection is key to improving treatment outcomes. (medscape.com)
  • CT scanning and MRI are approximately equivalent, and both are significantly superior to US, in the detection of enlarged lymph nodes. (medscape.com)
Surgical1
  • Although lymphadenectomy helps define the risk for recurrence and enables surgical staging to guide treatment decisions, the procedure carries the risk for surgical harm and lymphedema. (medscape.com)
Intermediate1
  • T]he sentinel-lymph-node mapping procedure is the best intermediate between complete versus no lymphadenectomy. (medscape.com)
Imaging1
Frequency2
  • Patterns B and C patients also mostly presented at stage I with negative lymph nodes but had greater frequency of recurrence. (stanford.edu)
  • It ranks fifth in frequency behind cancer of the uterus, cervix, ovary, and vulva. (medscape.com)
Distant1
  • Malignant diseases of the vagina are either primary vaginal cancers or metastatic cancers from adjacent or distant organs. (medscape.com)
Commonly1
  • Gynecological cancers are some of the most commonly occurring malignancies in women. (nshealth.ca)
Cervix1
Evidence1
  • Controversies in the Management of Gynecological Cancers offers a unique assessment of the opposing sides of the controversial issues associated with gynecological cancers, and aims to provide professionals in the field with a keener sense of the underlying evidence-base and a starting point from which to follow the ongoing debate. (nshealth.ca)
Regions1
  • Moreover, 17% of positive sentinel lymph nodes were identified outside regions traditionally included in complete lymphadenectomy. (medscape.com)
Primary1
  • Primary vaginal cancers are defined as arising solely from the vagina, with no involvement of the external cervical os proximally or the vulva distally. (medscape.com)
Institute1
Care2
High1
  • Endometrial cancer is more common in high-resource countries where obesity rates are high. (msdmanuals.com)
Result1
  • That event concerned ureteral injury during sentinel lymph node dissection and did not result in long-term injury. (medscape.com)