PC12 CellsApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinCell Line, TumorX-Linked Inhibitor of Apoptosis ProteinCell SurvivalApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsSignal TransductionCaspase 8MitochondriaEnzyme ActivationTumor Suppressor Protein p53Fas Ligand ProteinTumor Cells, CulturedCells, CulturedCytochromes cbcl-X ProteinCell ProliferationAnnexin A5Blotting, WesternCell LineAmino Acid Chloromethyl KetonesCysteine Proteinase InhibitorsProto-Oncogene ProteinsFlow CytometryCell CycleAntineoplastic AgentsPoly(ADP-ribose) PolymerasesTransfectionEnzyme InhibitorsReactive Oxygen SpeciesCell DivisionTNF-Related Apoptosis-Inducing LigandJurkat CellsRNA, Small InterferingDown-RegulationDose-Response Relationship, DrugCaspase 7HL-60 CellsCell DeathMembrane Potential, MitochondrialPhosphorylationTumor Necrosis Factor-alphaGenes, bcl-2RNA, MessengerMembrane GlycoproteinsUp-RegulationTime FactorsNecrosisbcl-2 Homologous Antagonist-Killer ProteinCytochrome c GroupProto-Oncogene Proteins c-aktMyeloid Cell Leukemia Sequence 1 ProteinNF-kappa BDNA DamageBH3 Interacting Domain Death Agonist ProteinReverse Transcriptase Polymerase Chain ReactionMice, Inbred C57BLStaurosporineGene Expression Regulation, Neoplasticbcl-Associated Death ProteinCarrier ProteinsProtein-Serine-Threonine KinasesCeramidesAntineoplastic Agents, PhytogenicMice, KnockoutImmunohistochemistryGene Expression RegulationOxidative StressHeLa CellsReceptors, TNF-Related Apoptosis-Inducing LigandDrug SynergismCaspase 2Neoplasm ProteinsFas-Associated Death Domain ProteinMitogen-Activated Protein KinasesMembrane ProteinsRNA InterferenceCysteine EndopeptidasesGene ExpressionApoptotic Protease-Activating Factor 1DNA-Binding ProteinsEpithelial CellsMice, NudeModels, BiologicalCell NucleusReceptors, Tumor Necrosis FactorMutationCell DifferentiationMolecular Sequence Data