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  • FKHR
  • Although no consistent genetic alterations have been identified thus far in eRMS, ∼80% of aRMS patients display typical chromosomal translocations t(2;13)(q35;q14) or t(1;13)(p36;q14) encoding for fusion proteins PAX3/FKHR or PAX7/FKHR, respectively ( 3 ). (aacrjournals.org)
  • embryogenesis
  • On the other hand, there is ample evidence for direct and indirect activation of by Pax3 during embryogenesis (reviewed by Braun and Gautel, 2011). (a-443654.com)
  • myofibers
  • We observed a massive reduction, but not complete loss, of Pax7-positive SCs on isolated myofibers of Pax7CE/loxP-Gu mice already 1211441-98-3 1 day after the end of the TAM treatment (Figure 1N). (a-443654.com)
  • demonstrate
  • We demonstrate that RNA inhibition of transcription factors can facilitate reprogramming, and that treatment with DNA methyltransferase inhibitors can improve the overall efficiency of the reprogramming process. (nih.gov)
  • histone
  • the interaction links PAX7 to a WDR5-containing histone methyltransferase complex (By similarity). (genecards.org)