DiseasesAnalytical, Diagnostic and Therapeutic Techniques and Equipment
ThymomaThymus NeoplasmsThymectomyMyasthenia GravisParaneoplastic SyndromesThymus Hyperplasia
MyastheniaMalignant thymomaTumorThymomasThymectomyMetastatic thymomaAntibodiesImmunodeficiencyLymphomaRecurrenceTumorsRecurrentCases of thymomaResectionInvasiveSymptomsDiagnosisChemotherapyMalignanciesPathologicLimbic encephalitisUnderwentNeoplasmThymic hyperplasiaTreatmentCisplatinRetrospectiveHyperplasiaHypogammaglobulinemiaThoracicMediastinalPrognosticSurvivalLymph nodesSurgicalMedianCervicalLymphoidCancerPatient'sAutoimmuneUsually occursChestHistologicPathologyAntibodyBiopsyCancersConcurrentMethodsResults
Myasthenia27
Malignant thymoma3
  • The prognosis is worse for patients with symptomatic thymomas because these patients are more likely to have a malignant thymoma. (medscape.com)
  • 3. Treatment of pediatric malignant thymoma: long-term remission in a 14-year-old boy with EBV-associated thymic carcinoma by aggressive, combined modality treatment. (nih.gov)
  • 7. Nonsurgical management of malignant thymoma. (nih.gov)
Tumor18
  • Several series have indicated the importance of initial tumor invasion, as well as the extent of surgical resection, as predictors of recurrence and survival after thymoma resection. (nih.gov)
  • Thymoma behaves as a rather indolent tumor, with most deaths from causes unrelated to thymoma or its direct treatment. (nih.gov)
  • A thymoma is a cancerous tumor in your thymus gland, a small gland in your chest that helps produce immune cells. (healthline.com)
  • At this point, the tumor is known as a metastatic thymoma. (healthline.com)
  • My fiance was diagnosed with a thymoma 11/21 and has undergon 4 chemo cycles (PAC Regimen), the tumor shrank drastically and he will now be able to have surgery on 4/11. (cancer.org)
  • Thymic carcinoma or type C thymoma is a thymic epithelial tumor that exhibits clear-cut cytological atypia and histological features no longer specific to the thymus. (cancer.gov)
  • Masses in this location are usually remembered as the "terrible T's": thymoma, teratoma/germ cell tumor, "terrible" lymphoma, and thyroid. (acpinternist.org)
  • Masses in the anterior mediastinum are usually recalled as the "terrible T's": thymoma, teratoma/germ cell tumor, "terrible" lymphoma, and thyroid. (acpinternist.org)
  • Results -All patients were treated with excision of the tumor alone. (avma.org)
  • The patient decided to sue the doctor who missed the tumor. (getpocket.com)
  • Fourteen patients (64%) had a tumor demonstrated pathologically (5 lung, 4 thymoma, 2 breast, 2 ovarian teratoma) or radiologically (1 lung). (eur.nl)
  • Additional antibodies occurred in 7 patients (3 onconeuronal, 1 tumor-related, 2 cell surface, and 1 tumor-related and cell surface), all with neurologic symptoms or tumor reflecting the concurrent autoimmunity. (eur.nl)
  • Treatment and outcome were available from 21 patients (median follow-up 72 weeks, range 5-266): 5 had good response to immunotherapy and tumor therapy, 10 partial response, and 6 did not improve. (eur.nl)
  • A thymoma is typically a slow growing tumor. (itmig.org)
  • PLGA pellets loaded with 50% w/w 5-FU exhibited comparable, and significantly enhanced, antitumor activity (as measured by tumor volumes and survival) in vivo in a thymoma and colon cancer model, respectively, when compared to an equivalent bolus dose (120 mg/kg) of soluble 5-FU. (nih.gov)
  • We concluded that 5-FU-loaded PLGA pellets were more effective and specifically less erythrotoxic than 5-FU bolus injections and therefore may prove to be of benefit as an intraoperative adjunct therapy for patients with cancers that are sensitive to 5-FU and who are undergoing tumor resection. (nih.gov)
  • Primary tumors of the thymus are infrequent, the most common histologic type is thymoma, a neoplasm that derives from thymic epithelial cells and constitutes the most frequent anterior mediastinal tumor in adults ( 1 ). (amegroups.com)
  • The etiology of this tumor remains unknown, and due to its rarity, most research of thymoma have been based on single center reports. (amegroups.com)
Thymomas6
  • A trial conducted by the European Organisation for Research and Treatment of Cancer reported that among 16 patients with recurrent or metastatic thymomas, five complete remissions and four partial remissions were observed. (medscape.com)
  • Octreotide (0.5 mg SC q8hr) alone or with prednisone (0.6 mg/kg/day) was evaluated in 38 patients with advanced thymomas that expressed somatostatin receptors. (medscape.com)
  • Read on to learn about where thymomas usually metastasize, how fast a thymoma can spread, and how a metastatic thymoma can be diagnosed and treated. (healthline.com)
  • The single most important factor predicting the outcome of patients with thymomas is evidence of invasion. (medscape.com)
  • Despite its usual favorable outcome, thymomas are considered malignant tumors as on occasion they can metastasize and/or recur and in rare cases lead to death of the patient. (itmig.org)
  • A retrospective cohort of patients who underwent thymectomy for thymomas of 5 cm or larger at the National Cancer Institute (INCan) of México from January 2005 to December 2016 was analyzed. (amegroups.com)
Thymectomy6
  • Therefore, the patient received total thymectomy. (hindawi.com)
  • Thymectomy should be performed in all patients with thymoma. (acpinternist.org)
  • This technique was safe and effective in all of our 8 patients who underwent trans-sternal thymectomy. (ispub.com)
  • In general, MG centers have developed protocols for the care of MG patients and have a team of neurologists, surgeons, pulmonologists, intensivists and respiratory care specialists, nurses and anesthesiologists caring for MG patients undergoing thymectomy. (ispub.com)
  • Eight patients underwent thymectomy from January 2003 to October 2005, who were not considered to be difficult intubation, did not have pre-existing pulmonary disease and were not in crisis or in need of preoperative ventilatory support were enrolled for the study. (ispub.com)
  • Thymectomy-a surgical procedure that removes thymus gland tissue from the chest cavity-has been an established therapy for non-thymomatous MG, or MG without thymoma, for more than 60 years (based on retrospective, non-randomized studies). (nih.gov)
Metastatic thymoma6
Antibodies10
  • Patients have low total serum antibodies. (wikipedia.org)
  • In addition to these autoantibodies, patients with thymoma-associated MG produce autoantibodies to a variety of neuromuscular antigens, including antibodies to the skeletal muscles calcium release channel and antibodies to cytoplasmic filamentous proteins. (ispub.com)
  • A total IgG level within the normal range does not exclude specific IgG antibody deficiency (eg, deficient antibodies to polysaccharides), and this should be specifically sought in patients who have recurrent infections, total IgG levels toward the lower bound of normal, and IgA deficiency. (medscape.com)
  • Up to 50% of these AChR antibody‒negative patients have antibodies to muscle-specific receptor tyrosine kinase (MuSK), a surface membrane enzyme that helps AChR molecules aggregate during development of the neuromuscular junction. (msdmanuals.com)
  • The clinical significance of anti-MuSK antibodies is still under study, but patients with these antibodies are much less likely to have thymic hyperplasia or a thymoma, may be less responsive to anticholinesterase drugs, and may require more aggressive early immunotherapy than patients who have AChR antibodies. (msdmanuals.com)
  • Objective: We report the clinical features, comorbidities, and outcome of 22 newly identified patients with antibodies to the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR). (eur.nl)
  • Caspr2 antibodies have been associated with limbic encephalitis and neuromyotonia, 1 , 2 but our patient showed unusual Caspr2-associated spinal myoclonus. (neurology.org)
  • All patients had thymoma with seropositivity for anti-acetylcholine receptor antibodies. (elsevierpure.com)
  • Fifty-two patients (53.6%) tested positive for anti-JCV antibodies. (cnr.it)
  • Immunophenotyping is essential in detecting and monitoring immunodeficiency in patients with a thymoma, since treatment with IVIG may potentially replace the defective antibody production.14 IgG antibodies to toxoplasmosis and cytomegalovirus should be determined to evaluate whether a patient is at risk of reactivated infections. (imacst.com)
Immunodeficiency7
  • Thymoma with immunodeficiency (also known as "Good syndrome") is a rare disorder that occurs in adults in whom hypogammaglobulinemia, deficient cell-mediated immunity, and thymoma (usually benign) may develop almost simultaneously. (wikipedia.org)
  • The immunodeficiency may occur before or after the diagnosis of a thymoma. (wikipedia.org)
  • Generally it can be defined as an adult-onset primary immunodeficiency associated with thymoma, hypogammaglobulinemia, diminished B and T cells, and inverted CD4/CD8+ ratio. (wikipedia.org)
  • In patients with primary humoral immunodeficiency and chronic productive cough, high-resolution computed tomography (HRCT) is helpful in evaluating the extent of lung damage. (medscape.com)
  • Patients who are first diagnosed with immunodeficiency when they are older than 45 years should undergo serum protein electrophoresis and an imaging study to rule out thymoma . (medscape.com)
  • Our rationale for choosing to define Good syndrome as immunodeficiency with thymoma, a broader classification, is because the pathogenesis of the disease MYO7A remains unknown and patients have several other immunological impairments in addition to hypogammaglobulinemia (Table 1). (imacst.com)
  • If immunologic test results are normal, testing should be performed periodically if the clinical suspicion of Good syndrome persists, because there can be an interval between the diagnosis of immunodeficiency and/or thymoma and development of infection.15 Infectious Complications The initial clinical features of Good syndrome are varied. (imacst.com)
Lymphoma9
  • The simultaneous occurrence of thymoma and peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) has not been previously reported, to our knowledge. (medscape.com)
  • The present case is unique because it involves a composite thymoma and peripheral T-cell lymphoma not otherwise specified (PTCL-NOS). (medscape.com)
  • We report a rare case of a patient with synchronous cervical thymoma and diffuse large B-cell lymphoma. (biomedcentral.com)
  • The final pathology review confirmed that the arm mass was diffuse large B-cell lymphoma, but the neck mass was cervical thymoma, type B1, not diffuse large B-cell lymphoma. (biomedcentral.com)
  • Concurrent cervical thymoma and diffuse large B-cell lymphoma were proven after a careful pathology review, leading to better clinical management. (biomedcentral.com)
  • It is, therefore, possible to have concurrent cervical thymoma and malignant lymphoma. (biomedcentral.com)
  • The clinical management should be different if the patient is diagnosed with concurrent cervical thymoma and malignant lymphoma. (biomedcentral.com)
  • In this paper, we report a case of MG related to cervical thymoma and concurrent diffuse large B-cell lymphoma (DLBCL) in an 81-year-old woman. (biomedcentral.com)
  • Contrast-enhanced chest CT scan was highly suspicious for a posttransplant lymphoma or thymoma. (hindawi.com)
Recurrence3
  • In one case, the patient showed complete regression to the thymoma and associated symptoms and has remained without radiologic recurrence after 12 months. (medscape.com)
  • Recurrence of thymoma was observed in 2 cats and 1 dog, and a second surgery was performed in each, with subsequent survival times of 5, 3, and 4 years following the first surgery. (avma.org)
  • Early-stage disease should be treated aggressively with surgery (and post-operative radiation in select cases, especially in patients with thymic carcinoma) to decrease the chances of recurrence. (itmig.org)
Tumors7
  • Thymoma is the most common neoplasm of the anterior mediastinum, accounting for 20-25% of all mediastinal tumors and 50% of anterior mediastinal masses. (medscape.com)
  • Thymoma and thymic carcinoma are rare epithelial tumors, which originate from the thymus gland. (wjgnet.com)
  • 18. [Thymoma and thymoma-like tumors of the anterior mediastinum--therapeutic problems in observed patients]. (nih.gov)
  • However, in the absence of an approved vaccine against Covid-19 at this time and uncertainties about what type of vaccine will be approved eventually, no recommendations can be made at present about the potential use of a Covid-19 vaccine in patients with thymic epithelial tumors. (itmig.org)
  • La tinció immunohistoquímica es fa servir en el diagnòstic de cèl·lules anormals com les que es troben en els tumors cancerosos, entre altres afeccions. (wikipedia.org)
  • In addition, it improves the outcomes with minimal complications in patients with mediastinal and esophageal tumors. (hcgmanavatacancer.org)
  • ITMIG Imaging LibraryWe present a searchable, annotated library of images for normal and thymic malignancy patients, including images that show tumors in different stages with short radiological explanations. (curie.fr)
Recurrent2
  • Most patients present with an immunodeficient state and recurrent sinopulmonary infections in their 4th or 5th decade of life. (wikipedia.org)
  • Most patients experienced infectious complications such as recurrent sinopulmonary infections secondary to encapsulated organisms (spp, in the United States or in Europe. (imacst.com)
Cases of thymoma2
Resection2
  • Staging is an important prognostic marker, similar to complete resection of the thymoma. (itmig.org)
  • To investigate the impact of the COVID-19 pandemic on lung cancer surgery, we compared between 2018-2019 (prepandemic group) and 2020-2021 (pandemic group) in the respect of patient characteristics, pathological findings, and short-term outcome after lung cancer resection by Mann-Whitney and Fisher's exact tests. (nagoya-u.ac.jp)
Invasive5
  • [ 7 ] Potential candidates for chemotherapy include approximately one third of the patients with an invasive thymoma that later metastasizes and all patients with stage IV disease. (medscape.com)
  • Case reports have documented the administration of oral glucocorticoids resulting in regression of an invasive thymoma. (medscape.com)
  • The 15-year survival rate is 12.5% for a person with an invasive thymoma and 47% for a person with a noninvasive thymoma. (medscape.com)
  • 20. [Multidisciplinary treatment of advanced invasive thymoma]. (nih.gov)
  • These features also help patients undergo complex surgeries through a minimally invasive approach. (hcgmanavatacancer.org)
Symptoms11
  • But, not everyone has symptoms when they have a thymoma. (healthline.com)
  • As many as 30-40% of patients who have a thymoma experience symptoms suggestive of MG. An additional 5% of patients who have a thymoma have other systemic syndromes, including red cell aplasia, dermatomyositis, systemic lupus erythematosus (SLE), Cushing syndrome, and syndrome of inappropriate antidiuretic hormone secretion (SIADH). (medscape.com)
  • Patients usually present with symptoms of irritation of the mediastinal structures and symptoms may range from none to respiratory distress. (hindawi.com)
  • Patients may be asymptomatic and are often diagnosed after obtaining a chest radiograph for another reason, whereas others present with symptoms related to compression of adjacent structures. (acpinternist.org)
  • This patient has an anterior mediastinal mass (arrow) and neurologic symptoms. (acpinternist.org)
  • Common symptoms are ptosis and diplopia, which this patient has. (acpinternist.org)
  • For patients with severe bulbar symptoms or respiratory compromise (myasthenic crisis), plasmapheresis is used. (ispub.com)
  • In a Mayo Clinic series, 95% of 50 patients with a late onset of adult hypogammaglobulinemia had grossly abnormal findings on sinus films but did not necessarily have symptoms of purulent sinusitis. (medscape.com)
  • People with thymoma may develop different SYMPTOMS . (itmig.org)
  • Familial NIID is more diverse, with the main dominant symptoms being muscle weakness (NIID-M), dementia (NIID-D), and parkinsonism (NIID-P). Furthermore, recently, a GGC-repeat expansion in the Notch 2 N-terminal like C (NOTCH2NLC) gene, which produces a toxic polyglycine-containing protein (uN2CpolyG) in patients with NIID, has been associated with the pathogenesis of ALS. (bvsalud.org)
  • One third of patients are asymptomatic and will be referred due an incidental mediastinal mass on chest images, almost one third of thymoma patients will present MG and another third part will have local symptoms ( 2 ). (amegroups.com)
Diagnosis6
  • The authors evaluated 136 patients seen at the Johns Hopkins Hospital between 1957 and 1997 with a pathologic diagnosis of thymoma. (nih.gov)
  • Early treatment and diagnosis can help keep a thymoma from spreading. (healthline.com)
  • Going one step further, we give our patients the advantage of being able to consult with several experienced thymoma doctors, each of whom is extensively trained in a different aspect of diagnosis and treatment. (moffitt.org)
  • Patients who come to Moffit without a confirmed diagnosis - or seeking a second opinion - first receive a comprehensive diagnostic evaluation. (moffitt.org)
  • 8. [Diagnosis and therapy of thymoma]. (nih.gov)
  • Early diagnosis and identification of the subtype informs treatment and can help improve patient outcome. (imperial.ac.uk)
Chemotherapy7
  • [ 12 ] One patient refused surgery, nine (82%) had complete resections, and two (18%) who had been receiving radiation therapy and consolidation chemotherapy had incomplete resections. (medscape.com)
  • Thymoma is a rare neoplasm of the mediastinum, for which very few data on the efficacy and safety of chemotherapy and chemoradiotherapy are available. (nih.gov)
  • Intensive chemotherapy with cisplatin, doxorubicin, cyclophosphamide, etoposide and granulocyte colony-stimulating factor for advanced thymoma or thymic cancer: preliminary results. (nih.gov)
  • We have several medical oncologists whose sole area of focus is treating lung cancers with chemotherapy medications, including novel drug combinations that are especially promising in the realm of thymoma treatment. (moffitt.org)
  • 3.1.2 At least one prior line of platinum-based chemotherapy or patient must have refused cytotoxic chemotherapy. (nih.gov)
  • 3.1.3 Patients must not have received chemotherapy, radiation therapy, or undergone major surgery within 4 weeks prior to enrollment. (nih.gov)
  • Thymoma tended to be advanced, and four patients with Masaoka stage IVa required radiation therapy or chemotherapy. (elsevierpure.com)
Malignancies5
  • Clinicians should have an increased awareness of the possibility of second primary malignancies in patients with thymoma. (nih.gov)
  • A review of the Surveillance, Epidemiology, and End Results (SEER) database of thymoma cases in the United States (1973-1988) identified 849 cases, of which 66 had second malignancies. (medscape.com)
  • Evidence supports an increased risk of second primary malignancies in patients with thymoma. (biomedcentral.com)
  • Remember that patients with ataxia-telangiectasia and other DNA processing/repair enzyme defects are particularly prone to radiation-induced malignancies. (medscape.com)
  • Patients with the inherited form appear to be at increased risk for secondary nonocular malignancies such as osteosarcoma, malignant fibrous histiocytoma, and fibrosarcoma. (nih.gov)
Pathologic1
  • However, the patient was found to have MG-related cervical thymoma after pathologic review, while the forearm mass was confirmed to be DLBCL. (biomedcentral.com)
Limbic encephalitis1
  • Four syndromes were identified: 12 (55%) patients presented with distinctive limbic encephalitis (LE), 8 (36%) with limbic dysfunction along with multifocal/diffuse encephalopathy, one with LE preceded by motor deficits, and one with psychosis with bipolar features. (eur.nl)
Underwent4
  • A 46-year-old man underwent thymoma surgical removal. (wjgnet.com)
  • We retrospectively analyzed consecutive natalizumab-treated multiple sclerosis patients who underwent a JCV antibody test through a two-step enzyme-linked immunosorbent assay (STRATIFY test) to the measure of serum usCRP levels, and to perform blood and urine JCV PCR. (cnr.it)
  • Methods: We collected data from patients with primary lung cancer who underwent thoracic surgery between 2018 and 2021. (nagoya-u.ac.jp)
  • Results: From 2018 through 2021, 936 patients with primary lung cancer underwent surgical intervention in our institute and were included in this study. (nagoya-u.ac.jp)
Neoplasm3
  • Cervical thymoma is a rare thymic epithelial neoplasm. (biomedcentral.com)
  • Cervical thymoma is a rare neoplasm of the thymic epithelium, which arises in an ectopic thymus that originated from an undescended thymus during embryonic development. (biomedcentral.com)
  • Thymoma , the most common neoplasm of the anterior mediastinum , originates within the epithelial cells of the thymus . (findmeacure.com)
Thymic hyperplasia1
  • For the first time, we report a case of thymic hyperplasia in a patient 2 years after bilateral lung transplantation. (hindawi.com)
Treatment16
  • Demographic information, clinical staging data, surgical and adjuvant treatment details, and patient follow-up data were obtained from the patient record and from detailed patient or family interviews. (nih.gov)
  • See Thymoma Treatment Protocols for more information. (medscape.com)
  • This information would be useful in selecting patients that may benefit from EGFR inhibitors as part of their treatment regimen. (medscape.com)
  • The American Academy of Pediatrics has outlined guidelines for pediatric cancer centers and their role in the treatment of pediatric patients with cancer. (cancer.gov)
  • Physicians and researchers work close together to provide innovative treatment options for patients. (moffitt.org)
  • Cellular characteristics are inconsequential because they have no impact on patient treatment. (medscape.com)
  • Because of the well-documented propensity for late recurrences, long-term survival should be considered in terms of a 10-year follow-up after treatment of the thymoma. (medscape.com)
  • 5. [Combined treatment of thymoma. (nih.gov)
  • At WeHeal we are constantly striving to help patients evaluate their treatment options and decide what will achieve the best possible outcome. (weheal.org)
  • We believe in the importance of personalized medicine, and have developed a clinical research program which aims to identify the right treatment for the right patient at the right time. (dana-farber.org)
  • Thus, elucidating the mechanisms for autoantibody access to the CNS may provide a wider spectrum of treatment options for patients with these complex and puzzling disorders. (frontiersin.org)
  • For most patients with no history of thymoma-associated autoimmune disease or treatment-induced autoimmunity, it should be okay to receive an inactivated influenza vaccine. (itmig.org)
  • It should be noted that in severe cases, Covid-19 causes a clinical picture which is very similar to that observed in patients with thymoma experiencing widespread immune activation either due to treatment (e.g., as a complication of immunotherapy) or due to the disease itself (thymoma-associated multi-organ autoimmunity). (itmig.org)
  • The benefits for patients include shorter hospital stays, less tissue damage, reduced bleeding risk, fewer treatment-related complications, and early recovery. (hcgmanavatacancer.org)
  • By housing this advanced technology, HCG Manavata strives to help all patients have access to high-end treatment technologies. (hcgmanavatacancer.org)
  • Going forward, we wish to help more and more patients receive the right care the first time they visit HCG Manavata - through groundbreaking treatment technologies and innovative treatment approaches. (hcgmanavatacancer.org)
Cisplatin3
  • The objective of this pilot study was to assess the safety and efficacy of cisplatin, etoposide, and radiotherapy for thymoma. (nih.gov)
  • Patients with advanced, previously-untreated thymoma (Masaoka classification), measurable disease, and a performance status of 0-2 were eligible, and were treated with cisplatin-plus-etoposide, together with radiotherapy when possible. (nih.gov)
  • The combination of cisplatin and etoposide with or without radiotherapy is effective for advanced thymoma, and has an acceptable toxicity. (nih.gov)
Retrospective2
  • A single-institution retrospective study was conducted of five patients with stage IVA thymoma treated with pleuropneumonectomy. (medscape.com)
  • Methods: This was a retrospective review of patients diagnosed between May 2009 and March 2014. (eur.nl)
Hyperplasia1
  • Majority of patients with MG have thymic abnormalities: hyperplasia in 60 to 70 percent and thymoma in 10 to 12 percent( 2 ). (ispub.com)
Hypogammaglobulinemia4
  • Dr. Robert Good was first to describe the association between thymoma and hypogammaglobulinemia in 1954. (wikipedia.org)
  • Pulmonary function tests may show an obstructive pattern in patients with IgAD and hypogammaglobulinemia. (medscape.com)
  • DISCUSSION Definition The association between the presence of a thymoma and adult-onset hypogammaglobulinemia was first described by Dr Robert Good in 1955.2 There are a number of definitions for Good syndrome. (imacst.com)
  • Others choose to define it as hypogammaglobulinemia with thymoma consistent with Dr Goods case. (imacst.com)
Thoracic3
  • At Moffitt Cancer Center, we make it easy for patients with thymoma to connect with a specialist through our Thoracic Oncology Program. (moffitt.org)
  • As a thoracic oncologist she cares for patients with cancers of the chest including lung cancer, mesothelioma and thymoma. (yale.edu)
  • He sees patients in the UCSF Thoracic Surgery and Oncology Clinic at the Helen Diller Family Comprehensive Cancer Center. (ucsfhealth.org)
Mediastinal1
  • Thymoma and thymic carcinoma originate within the epithelial cells of the thymus, resulting in an anterior mediastinal mass. (cancer.gov)
Prognostic1
  • The protocols help pathologists to report effectively about diagnostic and prognostic findings, which are critical to patient care and the collection of collaborative stage data. (partnershipagainstcancer.ca)
Survival3
  • [ 8 ] In 32 patients, a 47% complete and 90% overall response rate was noted with a median survival time of 15 months. (medscape.com)
  • To date, only five patients (45.5%) have died, and the median survival time is 128.1 months (95% confidence interval = 51.6-204.6 months). (nih.gov)
  • Patients treated with chemoradiotherapy had a good response and long progression-free survival. (nih.gov)
Lymph nodes1
Surgical1
  • AB - A hospital with a comprehensive psychiatric service provides a nearby general hospital with staff and backup for psychiatric consultations, crisis intervention, concurrent psychiatric care of medical-surgical patients, follow-up for psychiatric hospitalization or referrals, and staff education. (nih.gov)
Median1
Cervical2
  • We report the first and unique case of a man with cervical intradural B3 thymoma metastasis. (wjgnet.com)
  • The rarity of cervical thymoma and its histological similarities with type B1 thymoma (a predominance of lymphoid cells) present diagnostic challenges for pathologists and hematologists. (biomedcentral.com)
Lymphoid2
  • Thymoma originates within the epithelial cells of the thymus, a lymphoid organ located in the anterior mediastinum. (medscape.com)
  • Other, more rare subtypes such as micronodular thymoma with lymphoid stroma are also recognized. (itmig.org)
Cancer9
  • If the thymoma has spread, doctors may need to use a variety of tests to find the cancer and where it's spread to. (healthline.com)
  • 5 ] At these pediatric cancer centers, clinical trials are available for most types of cancer that occur in children and adolescents, and the opportunity to participate is offered to most patients and their families. (cancer.gov)
  • Taking Care of Your Health features cancer-related information, health tips, patient stories and more. (moffitt.org)
  • RET fusions occur as a rare mechanism of acquired resistance to osimertinib in patients with EGFR mutation-positive non-small cell lung cancer. (imperial.ac.uk)
  • Newly diagnosed cancer patients and their families and/or care-givers no longer need to manage various appointments, record keeping and communication between providers. (dignityhealth.org)
  • We offer a wide range of services, from financial planning to creative arts to spiritual counsel, to support our patients through their cancer experiences. (dana-farber.org)
  • He is a specialist advisor to Cancer Backup and CancerHelpUK, the patient information arm of Cancer Research UK. (nuffieldhealth.com)
  • He specializes particularly in treating non-small cell lung cancer, small cell lung cancer, thymoma and thymic carcinoma, and mesothelioma. (ucsfhealth.org)
  • Moreover, the monthly number of surgeries for lung cancer in our institution during 2020-2021 was compared with the number of newly diagnosed COVID-19 patients in Japan by Spearman correlation analysis. (nagoya-u.ac.jp)
Patient's1
  • Each patient's thymoma specialist works hand-in-hand with a team of supportive care providers and oncology nurses to ensure the best possible quality of life. (moffitt.org)
Autoimmune3
  • However, for patients with a history of thymoma-associated autoimmunity or in the presence of an active autoimmune disease, or in patients who have previously experienced immune-related toxicity with immunotherapy, there is a risk of worsening of autoimmunity due to additional immune stimulation caused by the influenza vaccine and caution should be exercised in these cases. (itmig.org)
  • In summary, the benefits of receiving an influenza vaccine are likely to outweigh the risks for most patients with thymoma who do not have an active or poorly controlled autoimmune condition. (itmig.org)
  • Hence, upon approval of a safe and effective Covid-19 vaccine (preferably not a live vaccine), for most patients with thymoma who do not have a clinical history of autoimmunity or an active autoimmune condition, the benefits of vaccination against Covid-19 might outweigh potential risks (please also refer to our response for influenza vaccination below) and it might be reasonable to consider vaccination. (itmig.org)
Usually occurs1
  • Thymoma usually occurs in people between the ages of 40 and 80. (itmig.org)
Chest1
  • There is a solution for patients with an allergy to iodinated contrast, the contrast used with chest CT scans: performing an MRI or performing the contrast-enhanced chest CT after steroid preparation for the iodinated contrast. (itmig.org)
Histologic1
Pathology2
  • 3.1.1Histological confirmation of thymoma (Group 1 only) orthymic carcinoma by the pathology department/CCR/NCI or the pathology department of participating institutions. (nih.gov)
  • ITMIG Pathology Slides LibraryWe present a searchable, annotated library of pathology slide images for thymoma patients. (curie.fr)
Antibody1
  • To assess JCV exposure in multiple sclerosis patients, we performed a serological examination, obtained the antibody index, performed real-time polymerase chain reaction (PCR) to detect JCV DNA in plasma and urine, and investigated the role of ultrasensitive C-reactive protein (usCRP) as a possible biological marker of JCV reactivation. (cnr.it)
Biopsy1
  • Jejunal biopsy specimens of patients with IgAD who have chronic diarrhea and malabsorption may show blunting of the villi. (medscape.com)
Cancers2
  • A consensus effort between the European Union Joint Action on Rare Cancers and the European Cooperative Study Group for Rare Pediatric Cancers estimated that 11% of all cancers in patients younger than 20 years could be categorized as very rare. (cancer.gov)
  • Robotic surgery is generally indicated in patients suffering from early-stage uterine cancers. (hcgmanavatacancer.org)
Concurrent1
  • Physical examination at Siriraj revealed a 7 × 5 cm left epitrochlear lymph node (LN) and a 2 cm right inguinal LN. Noticing ptosis of the left eyelid, the attending physician suspected a paraneoplastic syndrome such as MG. The patient reported that she had diplopia and progressive dysphagia before the excisions, with concurrent development of hoarseness during lengthy conversations. (biomedcentral.com)
Methods1
  • METHODS: Patients with advanced ALK+ NSCLC that progressed on crizotinib were randomized 1:1 to brigatinib 180 mg once daily (7-d lead-in, 90 mg) or alectinib 600 mg twice daily, aiming to test superiority. (imperial.ac.uk)
Results3
  • Results were available posthumously for patients 1, 3, and 4. (cdc.gov)
  • See patient satisfaction survey results for different Dana-Farber locations collected by Press Ganey, an independent company experienced in patient satisfaction surveying. (dana-farber.org)
  • Results: Taste disorders were observed in 16 (4.3%) of the 371 patients with MG. We concluded that taste disorders in 2.4% of patients with MG excluding other factors were associated with MG itself. (elsevierpure.com)