• A diagnostic EP study is always done before catheter ablation , usually as part of the same procedure. (hopkinsmedicine.org)
  • Electrophysiologists agree that ablation for AF is beneficial in some cases but disagree about when this invasive procedure should be performed in the trajectory of the patient's condition. (medscape.com)
  • Performed via a minimally invasive procedure, ablation alters tissue inside the heart where the irregular beats are triggered. (modernhealthcare.com)
  • 5 St. Jude Medical has also developed cardiac mapping technology to support complex ablation procedures while reducing procedure times. (modernhealthcare.com)
  • Results from a new clinical trial found overweight and obese patients with persistent and paroxysmal atrial fibrillation (AF) who lose weight prior to a catheter ablation procedure have improved clinical outcomes. (medicalxpress.com)
  • The study, led by researchers with UHealth-the University of Miami Health System and the Miller School of Medicine, identifies weight loss before undergoing an ablation procedure as a risk-factor reduction tool for AF patients. (medicalxpress.com)
  • People who have an irregular heartbeat called atrial fibrillation that is treated with a procedure called catheter ablation may have a reduced risk of dementia compared to those who are treated with medication alone. (medicalxpress.com)
  • A linear ablation element is provided adjacent to the circumferential ablation element in a combination assembly which is adapted for use in a less-invasive "maze"-type procedure in the region of the pulmonary vein ostia in the left ventricle. (justia.com)
  • He has pioneered a new circumferential ultrasound vein-ablation system to correct atrial fibrillation and performed the procedure on the world's first five patients. (jafib.com)
  • Lacking much of an evidence base and often viewed as too sick to gain a lot from the procedure, patients with AF and advanced HF aren't offered ablation very often. (mdedge.com)
  • A contraindication to an invasive electrophysiology procedure where insertion or manipulation of a catheter in the cardiac chambers is deemed unsafe. (fda.gov)
  • Methods This retrospective observational study included 120 patients (18 years or older) with paroxysmal or persistent atrial fibrillation who underwent RFA for de novo pulmonary vein isolation guided either by an UHDMS (n=63) or NUHDMS (n=57) for their index procedure. (unav.edu)
  • Healthcare resource utilization, clinical data, complications, patients' medical complaints related to the ablation procedure and patient's reported outcome measures will be prospectively traced and evaluated. (unav.edu)
  • A total of 320 patients who underwent an initial catheter ablation procedure for AF using a CB, HB, or LB in 2 hospitals were included. (go.jp)
  • In the present study, we sought to determine the pattern of LA performance change immediately and short-term after AF ablation and whether such alternation of LA function is related the procedure outcome at long-term follow-up. (biomedcentral.com)
  • 18 years old, had previous AF ablation or cardiac surgery procedure, valvular AF, congenital heart disease, previous atrioventricular node ablation, permanent pacing or no follow-up data. (biomedcentral.com)
  • All patients underwent a pulmonary vein isolation (PVI) procedure with additional lesions as required. (afibbers.org)
  • Thirty-nine percent of patients underwent a repeat procedure because of arrhythmia recurrence after a mean follow-up of 11 months. (afibbers.org)
  • At the last follow-up (a median of 4.3 years after the initial procedure), 66% of paroxysmal afibbers and 50% of persistent afibbers were in normal sinus rhythm without the use of antiarrhythmics. (afibbers.org)
  • The questionnaires were repeated 3 months and an average of 4.3 years after the initial ablation procedure. (afibbers.org)
  • However, patients with a successful ablation had significantly greater improvement in QoL than did those with an unsuccessful procedure, especially in regard to depression, AF symptoms, and AF severity. (afibbers.org)
  • Further, considering that about 70% of ablatees, whose procedure failed, still reduced their afib burden by at least 50%, brings one to the conclusion that RF ablation, whether successful or not, is likely to improve quality of life in close to 90% of those undergoing the procedure. (afibbers.org)
  • Electrophysiological studies are performed both as a diagnostic tool to determine the cause of an arrhythmia and as a curative procedure using radiofrequency catheter ablation. (medscape.com)
  • In neonates with the most severe form of Ebstein anomaly, the functional right ventricle is hypoplastic, and the patient is usually best treated by closing the tricuspid valve and, in effect, creating a tricuspid atresia physiology (Starnes procedure). (medscape.com)
  • When the patient is aged approximately 6 months, a bidirectional Glenn procedure (superior vena cava-to-pulmonary artery anastomosis) and shunt takedown is performed. (medscape.com)
  • The ablation procedure remains long, requires skills and expertise, and has a limited success rate, mostly because of non-durable lesions after PVI implying frequent redo procedures. (beat-af.com)
  • Reports for 30 of the studies identified patients by rhythm-control procedure, and the remaining five didn't specify TEE indications. (the-hospitalist.org)
  • The primary endpoint was freedom from any documented recurrence of atrial fibrillation after a single ablation procedure. (jafib.com)
  • The overall procedure time and radiation exposure were higher in the PVI+linear ablation group. (jafib.com)
  • Among patients with persistent atrial fibrillation, we found no difference in maintenance of sinus rhythm in either linear ablation or ablation of complex fractionated electrograms was performed in addition to pulmonary vein isolation in short- and long-term follow-up. (jafib.com)
  • al completed a prospective, multicenter, randomized trial of RFA vs. AAD as primary therapy for patients with symptomatic, paroxysmal AF. (acc.org)
  • To be included, patients had ≥2 episodes of symptomatic paroxysmal AF within the preceding six months but no episode of AF that was longer than seven days requiring cardioversion. (acc.org)
  • The Boston Scientific Cardiac Cryoablation System using the POLARx Cryoablation Balloon Catheters is indicated for the treatment of people with drug refractory, recurrent symptomatic paroxysmal atrial fibrillation (PAF). (fda.gov)
  • patients with symptomatic paroxysmal AF were examined. (anti-cancers.com)
  • In addition to our complete line of comprehensive arrhythmia management and cardiac resynchronization therapy (CRT) devices, the CardioMEMS™ HF System is the first and only FDA-approved heart failure monitoring device that, when managed by a physician, has been proven to significantly reduce hospital admissions and improve quality of life in NYHA class III HF patients who have been hospitalized in the previous 12 months. (modernhealthcare.com)
  • Catheter ablation success was defined as freedom from any sustained atrial arrhythmia recurrence after a 3-month blanking period following catheter ablation. (cepia.team)
  • Conclusion In patients treated with an NUHDMS, 25% had a repeat ablation for recurrent arrhythmia, whereas only 9% of patients treated with a UHDMS had one (61% relative risk reduction), resulting in an average cost saving per patient of euro1,600. (unav.edu)
  • DESIGN Retrospective analysis of the outcome of patients with ventricular arrhythmia treated with IABCP after transfer between 1992 and 1997. (bmj.com)
  • PATIENTS 21 patients (mean age 58 years) who underwent IABCP for control of ventricular arrhythmia. (bmj.com)
  • IABCP resulted in suppression of ventricular arrhythmia in 18 patients, of whom 13 were weaned from IABCP. (bmj.com)
  • After stabilisation of ventricular arrhythmia, 10 patients were maintained on medical treatment alone and one underwent endocardial resection. (bmj.com)
  • IABCP failed to control ventricular arrhythmia in three patients and was subsequently discontinued. (bmj.com)
  • In patients with impaired left ventricular function, medically refractory ventricular arrhythmia can present a difficult management problem. (bmj.com)
  • In such circumstances non-pharmacological methods of arrhythmia management such as endocardial resection and ventricular tachycardia ablation are currently employed, despite the high risk of these procedures in the unstable patient. (bmj.com)
  • In this report we describe a retrospective review of the efficacy of IABCP in controlling ventricular arrhythmia in patients resistant to antiarrhythmic drug treatment, repeated dc cardioversion, and pacing strategies. (bmj.com)
  • Between 1992 and 1997, 21 patients (17 male, four female) were transferred to our unit (a cardiac tertiary referral centre) with medically resistant ventricular arrhythmia for further management, and were considered suitable for IABCP. (bmj.com)
  • Consideration of IABCP was given to any patient with ventricular arrhythmia refractory to conventional treatment, but who would be suitable for more definitive treatment or who might otherwise have a reasonable quality of life if the arrhythmia were controlled. (bmj.com)
  • [ 6 ] As expected, success rates, complications, and recurrence rates vary with complex pediatric radiofrequency catheter ablation procedures, depending on operator and institutional experience. (medscape.com)
  • Methods We conducted a survey on Japanese patients with AAA treated between January 1, 2012, and December 31, 2014. (go.jp)
  • Methods and Results - Two hundred forty patients with a total of 358 ectopic foci initiating PAF were included. (tmu.edu.tw)
  • Methods and Results: We prospectively measured estimated glomerular filtration rate (eGFR), urinary albumin-to-creatinine ratio (UACR), and reactive hyperemia index (RHI) in 358 consecutive patients with AF before and 6 and 12 months after the ablation. (elsevierpure.com)
  • METHODS: Patients with the iATP algorithm were assigned to iATP-first and conventional ATP-first groups sequentially. (bvsalud.org)
  • METHODS: We included 1,184 patients who underwent initial AF catheter ablation between 2016 and 2021. (bvsalud.org)
  • Methods The improveD procEdural workfLow for cathETEr ablation of paroxysmal AF with high density mapping system and advanced technology (DELETE AF) study is a prospective, single-arm, international post-market cohort study designed to demonstrate a low rate of clinical atrial arrhythmias recurrence with an improved procedural workflow for catheter ablation of paroxysmal AF, using the most advanced point-by-point RF ablation technology in a multicenter setting. (unav.edu)
  • Methods and Results: Thirty patients (25 males, mean age = 54 ± 11 years) with drug-refractory paroxysmal AF were included. (nycu.edu.tw)
  • Methods - We prospectively enrolled consecutive patients presenting with multiple ICD shocks for VF refractory to antiarrhythmic drug therapy, exhibiting infrequent (≤3%), multifocal PVCs (≥3 morphologies). (stanford.edu)
  • Fine wires inside the catheter can help pinpoint any areas outside the sinus node that produce electrical signals, then remove them using catheter ablation. (hopkinsmedicine.org)
  • Numerous studies have documented the marginal efficacy of antiarrhythmic drugs (AAD) for maintaining sinus rhythm in patients with paroxysmal atrial fibrillation (AF). (acc.org)
  • If you have a patient with first episode of afib, and you choose to leave that patient in afib, five years later there will be enough remodeling where you'll never have the chance to get that patient back to sinus rhythm. (stopafib.org)
  • Note that permanent AF has been de-emphasized as this classification is largely determined by the decision of the patient and provider to cease attempts to restore and/or maintain sinus rhythm, not specific physiologic or clinical criteria. (acc.org)
  • Term used when there has been a joint decision by the patient and provider to cease further attempts to restore and/or maintain sinus rhythm. (acc.org)
  • The new guidelines remind readers that in some patients, maintenance of sinus rhythm is associated with improvements in symptoms and quality of life. (acc.org)
  • The efficacy of ablation for maintaining sinus rhythm is superior to antiarrhythmic therapy in selected patient populations, particularly in younger patients with minimal structural heart disease. (acc.org)
  • Cardiac resynchronization therapy for symptomatic patients with HF in sinus rhythm with a QRS duration of 130-149 ms, left bundle branch block QRS morphology, and an LVEF ≤ 35% despite best medical therapy gets a similar demotion. (tctmd.com)
  • We hypothesized the underlying mechanism was improvement in renal and endothelial function corresponding to AF burden, and investigated whether restoration of sinus rhythm (SR) after ablation affected these functions according to AF type. (elsevierpure.com)
  • IMPORTANCE: Catheter ablation is more effective than drug therapy in restoring sinus rhythm in patients with atrial fibrillation (AF), but its incremental effect on long-term quality of life (QOL) is uncertain. (duke.edu)
  • After a 3-month blanking period, 65% of patients with paroxysmal AF and 46% of those with persistent AF were in normal sinus rhythm without the use of antiarrhythmic drugs. (afibbers.org)
  • MULTAQ is an antiarrhythmic drug indicated to reduce the risk of hospitalization for atrial fibrillation (AFib) in patients in sinus rhythm with a history of paroxysmal or persistent AFib. (multaqhcp.com)
  • MULTAQ is contraindicated in patients in atrial fibrillation (AFib) who will not or cannot be cardioverted into normal sinus rhythm. (multaqhcp.com)
  • Introduction: The anatomic proximity between the esophagus and the coronary sinus (CS) might render the esophagus vulnerable to thermal injury during ablation. (nycu.edu.tw)
  • An average of 3.3±0.5 sites of localized reentry during VF were targeted for radiofrequency ablation (38.3±10.9 minutes) during sinus rhythm, rendering VF non-inducible with pacing. (stanford.edu)
  • The study aimed to evaluate the effect of RDN on cardiac diastolic function in patients with refractory hypertension and PAF. (hindawi.com)
  • The levels of NT-proBNP and metrics of echocardiography were measured before and after RDN in patients with refractory hypertension and PAF. (hindawi.com)
  • RDN could improve the diastolic function in patients with refractory hypertension and PAF. (hindawi.com)
  • In the treatment of refractory hypertension, renal artery ablation (RDN) has become the most important nonpharmaceutical treatment modality [ 1 - 3 ]. (hindawi.com)
  • The patients with refractory hypertension and PAF simultaneously were common in clinical. (hindawi.com)
  • In this study, we studied the changes in diastolic function in patients with refractory hypertension and PAF before and after RDN. (hindawi.com)
  • Boston Scientific Cardiac Cryoablation System and Accessories are balloon-tipped catheters that use cold energy (gas) to treat people with symptomatic recurrent paroxysmal atrial fibrillation (PAF) who do not respond to medicine (drug refractory). (fda.gov)
  • Fifty patients with drug refractory, recurrent symptomatic PAF were selected to participate in the additional study. (fda.gov)
  • Patients with symptomatic and drug-refractory AF who underwent first time AF ablation at Mayo Clinic (Rochester, MN) between April 2009 and May 2011 were included. (biomedcentral.com)
  • A 66-year-old man with drug refractory paroxysmal AF underwent catheter ablation. (authorea.com)
  • Atrial ventricular nodal ablation is recommended for patients refractory to medical therapy, usually older patients needing a pacemaker. (aafp.org)
  • Electrical Substrate Ablation for Refractory Ventricular Fibrillation: Results of the AVATAR Study. (stanford.edu)
  • Background - Refractory ventricular fibrillation (VF) is a challenging clinical entity, for which ablation of triggering premature ventricular complexes (PVCs) is described. (stanford.edu)
  • The St. Jude Medical TactiCathTM Quartz Contact Force Ablation Catheter provides physicians with an innovative solution designed to improve outcomes, efficiency and productivity during electrophysiology procedures worldwide. (modernhealthcare.com)
  • ST. JUDE MEDICAL is a market leader in the research, design and development of electrophysiology and interventional cardiology solutions for pediatric patients worldwide. (modernhealthcare.com)
  • This novel technology comes at an exciting time for cardiac electrophysiology (EP), with the further development of new technology such as pulse field ablation (PFA) which is also due to start in Blackrock Clinic this year. (hospitalprofessionalnews.ie)
  • In many patients, the tachycardia episode can be stopped by bearing down or rubbing the carotid artery. (hopkinsmedicine.org)
  • For example, though EARLY-AF reported serious adverse events in 3.2% of patients in the cryoablation group and 4% in the AAD group, adverse events in the cryoablation group included phrenic-nerve palsy compared with wide-complex tachycardia, syncope, and heart failure (HF) exacerbation in the AAD group. (medscape.com)
  • The lack of reproduction of clinical PSVT by programmed electrical stimulation, which is not uncommon in AV node reentrant tachycardia (AVNRT), is a dilemma in making the decision of the therapeutic end point of radiofrequency catheter ablation. (tmu.edu.tw)
  • Slow-pathway catheter ablation is highly effective in eliminating spontaneous PSVT in which the tachycardia is not inducible despite the presence of dual AV node pathways. (tmu.edu.tw)
  • Not only is the risk of death in patients with AF twice that of patients without AF, but AF can result in myocardial ischemia or even infarction, heart failure exacerbation, and tachycardia-induced cardiomyopathy if the ventricular rate is not well-controlled. (ahrq.gov)
  • Whether or not a rhythm-control strategy is adopted, adequate rate control should be achieved in all patients with AF to prevent myocardial infarction (if significant coronary artery disease is present), exacerbation of heart failure, and tachycardia-induced cardiomyopathy and to alleviate symptoms. (ahrq.gov)
  • 1.5 cm). e Should be used with caution in patients at risk for torsades de pointes ventricular tachycardia. (multaqhcp.com)
  • RESULTS Before IABCP, 10 patients had incessant monomorphic ventricular tachycardia and 11 had paroxysmal ventricular tachycardia and/or ventricular fibrillation (VT/VF). (bmj.com)
  • Due to an increased risk of sudden cardiac death, people with Wolfe-Parkinson White syndrome are advised to have curative catheter ablation . (hopkinsmedicine.org)
  • Patients in both groups were monitored with an implantable cardiac monitoring device for 1 year posttreatment. (medscape.com)
  • Our EnSite™ Cardiac Mapping System supports physicians during both contact force and non-contact force ablation procedures by creating three-dimensional models that are based on the anatomy of the patient's own cardiac chamber. (modernhealthcare.com)
  • Similar to persistent AF, paroxysmal atrial fibrillation (PAF) could also have a significant impact on cardiac diastolic function. (hindawi.com)
  • Theoretically, the RDN also has a certain effect on cardiac diastolic function in these patients. (hindawi.com)
  • The trial "should, if anything, help eradicate the current somewhat nihilistic approach to atrial fibrillation management in patients with advanced heart failure," said Dr. Gustafsson, medical director of cardiac transplantation and mechanical circulatory support, Rigshopsitalet Copenhagen University Hospital. (mdedge.com)
  • In addition, the clinical study was expanded to assess the safety and effectiveness of the POLARx FIT cryoablation catheter, which is intended to be used for people with cardiac anatomy that is not suited to the POLARx catheter. (fda.gov)
  • In a study by Brown et al from the Mayo clinic the results of 539 patients who had 604 cardiac operations is described. (medscape.com)
  • Surgical treatments for atrial fibrillation are reserved for patients who are undergoing cardiac surgery for other reasons. (aafp.org)
  • IABCP was maintained until cardiac transplantation in five patients. (bmj.com)
  • The purpose of this clinical study is to test the hypothesis that market released Cardiac Resynchronization Therapy (CRT) devices which contain the AdaptivCRT® (aCRT) algorithm have a superior outcome compared to standard CRT devices in CRT indicated patients with normal atrio-ventricular (AV) conduction and left bundle branch block (LBBB). (stanford.edu)
  • Cardiac complications constitute a major cause of postoperative morbidity and mortality in surgical patients. (medscape.com)
  • In this video interview, Dr. Hugh Calkins, President of the Heart Rhythm Society and a member of the guidelines writing committee, discusses what afib patients should know about these new afib guidelines. (stopafib.org)
  • The guidelines contain some very significant changes that affect afib patients. (stopafib.org)
  • I'd say number one is that the CHA 2 DS 2 -VASc score has now been recommended for risk stratification of stroke risk in afib patients. (stopafib.org)
  • As everyone looked at the scientific evidence suggesting that aspirin prevents stroke in afib-as you know the data really isn't there, and this is a data driven process-the only place where aspirin is mentioned is for patients with a CHA 2 DS 2 -VASc risk score of 1. (stopafib.org)
  • In patients with permanent AFib, MULTAQ doubles the risk of death, stroke, and hospitalization for heart failure. (multaqhcp.com)
  • The CardioMEMS HF System and St. Jude Medical's left ventricular assist technology is transforming patient outcomes and altering patient and physician experiences with heart failure. (modernhealthcare.com)
  • While catheter ablation is a common AF treatment option, researchers are continuously evaluating how to improve AF ablation patient outcomes. (medicalxpress.com)
  • The authors of this trial would like to see additional trials focused on assessing the role of weight and weight loss in improving AF ablation outcomes and potentially identifying novel procedural approaches. (medicalxpress.com)
  • Backgrounds: We hypothesized radiofrequency Catheter ablation (RFCA) of atrial fibrillation (AF) in patients with structural heart disease (SHD) results in outcomes comparable to those with lone AF. (elsevierpure.com)
  • We compared patient characteristics, short- and long-term procedural outcomes, resource usage, and clinical outcomes followed up to 16 months between the two treatment groups. (unav.edu)
  • The Self-Rating Depression Scale, Self-Rating Anxiety Scale, and Medical Outcomes Survey 36-item Short-Form questionnaires were completed by these patients at baseline, and at 3, 6, 9, and 12 months of follow-up. (anti-cancers.com)
  • One study evaluated the outcomes of 32 patients who underwent surgery for Ebstein anomaly. (medscape.com)
  • Early detection, diagnosis and treatment of AF may help improve patient outcomes, since long history and duration of AF have been associated with recurrence. (medtechviews.eu)
  • Outcomes were compared against reference patients with VF who were unable or unwilling to undergo catheter ablation. (stanford.edu)
  • product safety and patient clinical outcomes. (who.int)
  • Recent clinical trial data show that ablation using St. Jude Medical catheter contact force technology is safe and effective for patients with AF. (modernhealthcare.com)
  • Objective To clarify the underlying diseases, clinical manifestations, and treatment strategies for Amyloid A (AA) amyloidosis (AAA) in Japanese patients. (go.jp)
  • The clinical and electrophysiologic characteristics of the 27 patients were compared with those of patients with dual AV node pathways and inducible AVNRT (group B, n = 55) and patients with dual AV node pathways alone without clinical PSVT (group C, n = 47). (tmu.edu.tw)
  • persistent AF, 30.6%) who underwent RFCA of AF and compared imaging, hemodynamic, electrophysiologic parameters and clinical outcome between the patients with (n=77) and without (n=351) SHD. (elsevierpure.com)
  • Conclusion: RFCA of AF in patients with selected SHD results in clinical outcome comparable to those with lone AF, in spite of advanced LA remodeling. (elsevierpure.com)
  • Catheter ablation had long taken atrial fibrillation (AF) rhythm control to the next level before clinical trials showed it could help keep AF patients with heart failure (HF) alive and out of the hospital. (mdedge.com)
  • Our trial suggests that in patients with atrial fibrillation and end-stage heart failure, catheter ablation may ameliorate the clinical course," states the CASTLE-HTx primary report, published in the New England Journal of Medicine, with Dr. Sohns as lead author, in tandem with his ESC presentation. (mdedge.com)
  • DESIGN, SETTING, AND PARTICIPANTS: An open-label randomized clinical trial of catheter ablation vs drug therapy in 2204 symptomatic patients with AF older than 65 years or 65 years or younger with at least 1 risk factor for stroke. (duke.edu)
  • The Clinical Application of the Deep Learning Technique for Predicting Trigger Origins in Paroxysmal Atrial Fibrillation Patients with Catheter Ablation. (cdc.gov)
  • A limitation of the study, observe Dr. Kirchhof and Dr. Sinning, "is that all patients had a clinical indication for a TEE, which might be a selection bias. (the-hospitalist.org)
  • Some clinicians consider AADs for initial treatment, whereas others follow a more invasive approach, such as cryoballoon ablation (also referred to as cryoablation) or radiofrequency ablation shortly after the initial diagnosis. (medscape.com)
  • We report a very rare case of left atrial thrombus formation required surgical treatment 14 months after cryoballoon ablation.Careful follow up with multimodalities is necessary for the detection and diagnosis of chronic phrase thrombus formation. (authorea.com)
  • Predictive value of premature atrial complex characteristics in pulmonary vein isolation for patients with paroxysmal atrial fibrillation. (cepia.team)
  • Thus, pulmonary vein isolation is the cornerstone of catheter ablation for paroxysmal atrial fibrillation. (cepia.team)
  • To assess whether premature atrial complex characteristics before catheter ablation can predict pulmonary vein isolation success in paroxysmal atrial fibrillation. (cepia.team)
  • Patients were included if they were treated with pulmonary vein isolation alone, and had 24-hour Holter electrocardiogram data before catheter ablation available and a follow-up of≥6 months. (cepia.team)
  • Preprocedural premature atrial complex analysis on 24-hour Holter electrocardiogram in paroxysmal atrial fibrillation may improve patient selection for pulmonary vein isolation. (cepia.team)
  • INTERVENTIONS: Pulmonary vein isolation, with additional ablation procedures at the discretion of the investigators, for the catheter ablation group (n = 1108) and standard rhythm and/or rate-control drugs selected and managed by investigators for the drug therapy group (n = 1096). (duke.edu)
  • We aimed to develop a convenient, safe, effective and fast method of pulmonary vein isolation (PVI) utilizing a penta-spline PFA catheter via a single femoral vein and a venous closure system. (go.jp)
  • The Pulmonary Vein Isolation (PVI) is the cornerstone of AF ablation, preventing recurrences, especially in patients with paroxysmal AF. (beat-af.com)
  • A key component of catheter ablation of AF is electrical isolation of the pulmonary veins from the left atrium. (hospitalprofessionalnews.ie)
  • Pulmonary vein isolation remains the cornerstone of atrial fibrillation (AF) ablation. (jafib.com)
  • However, due to high recurrence rates, especially in patients with persistent AF, PV antral isolation, complemented by linear ablation, autonomic modulation, and ablation of complex fractionated electrograms, have been attempted to increase the odds of success. (jafib.com)
  • We performed a prospective randomized trial by assigning 92 patients with persistent AF in 1:1 ratio to pulmonary-vein isolation plus ablation of electrograms showing complex fractionated activity (45 patients), or pulmonary-vein isolation plus additional linear ablation across the left atrial roof and mitral valve isthmus (47 patients). (jafib.com)
  • 3 ]. PV isolation has been the cornerstone of AF ablation. (jafib.com)
  • However, due to a relatively high recurrence rate, especially in patients with persistent AF, other ablation techniques have been developed, involving a PV antral isolation, often complemented by ablation lines, and ablation of complex fractionated atrial electrograms. (jafib.com)
  • We prospectively randomized patients undergoing pulmonary vein isolation to either additional linear ablation, versus the adjunctive ablation targeting fractionated or high-frequency electrograms ablation for the treatment of AF. (jafib.com)
  • Major guidelines, including those of the American College of Cardiology/American Heart Association/Heart Rhythm Society , European Society of Cardiology/European Association for Cardio-Thoracic Surgery , and Canadian Cardiovascular Society/Canadian Heart Rhythm Society recommend systemic anticoagulation for those with increased risk for stroke and anti-arrhythmic drugs (AADs) as the initial treatment for AF before considering ablation. (medscape.com)
  • 3,4 Compounding the challenge, the condition has been associated with increased risk for stroke, heart failure and death, all of which increase in frequency and severity as patients grow older. (modernhealthcare.com)
  • Amin A. Oral anticoagulation to reduce risk of stroke in patients with atrial fibrillation: current and future therapies. (medscape.org)
  • Dynamic changes of CHA2DS2-VASc score and the risk of ischaemic stroke in Asian patients with atrial fibrillation: a nationwide cohort study. (medscape.org)
  • The risk of stroke in patients with nonrheumatic AF is 5 percent per year, and this risk approaches 7 percent per year in patients with heart failure. (ahrq.gov)
  • 11 Importantly, when ischemic stroke occurs in patients with AF, it is either fatal or of moderate to high severity in most patients. (ahrq.gov)
  • Catheter ablation is a widely accepted therapy for atrial fibrillation (AF), of which stroke is a major complication. (authorea.com)
  • A stroke after catheter ablation has been reported in numerous studies not only in the acute phase but also in the chronic phase. (authorea.com)
  • Although the main concern of the medical profession when it comes to lone atrial fibrillation is stroke risk, the overwhelming concern of the patient is quality of life. (afibbers.org)
  • In addition to significant impact on quality of life, AF exposes patients to stroke, heart failure, dementia and death. (beat-af.com)
  • But OAC-resistant LA thrombi were two- to four-times as common in patients with than without certain features, including AF other than paroxysmal and higher CHADS2 and CHA2DS2-VASc stroke risk-stratification scores. (the-hospitalist.org)
  • Unlike stroke, the symptoms of AF are less-well known and more difficult to identify, often going undiagnosed, with up to 30% of patients not experiencing any symptoms. (medtechviews.eu)
  • When undetected and untreated, AF in some patients can lead to potential complications including stroke or heart failure. (hospitalprofessionalnews.ie)
  • Rare complications of paroxysmal SVT include myocardial infarction, congestive heart failure, syncope, and sudden death. (medscape.com)
  • Potential adverse events associated with ablation procedures include, but are not limited to, cardiovascular related complications, such as hematoma, effusion and infection. (modernhealthcare.com)
  • TEE imaging in select patients at an elevated risk of LA thrombus, despite anticoagulation status, may be a reasonable approach to minimize the risk of thromboembolic complications following cardioversion or catheter ablation," propose the study's authors, led by Antony Lurie, BMSC, Population Health Research Institute, Hamilton, Ont. (the-hospitalist.org)
  • However, medicine is lacking a reliable curative therapy for patients with persistent AF. (kit.edu)
  • Pulsed field ablation (PFA) is a non-thermal energy source with promising safety and efficacy advantages. (go.jp)
  • Results at 1 year showed a significantly lower recurrence of AF in the ablation group compared with the AAD group: 42.9% vs 67.8%, respectively. (medscape.com)
  • 1-3 Radiofrequency ablation (RFA) has been demonstrated to significantly reduce and eliminate AF episodes, reduce symptoms and reduce the need for medical therapy. (acc.org)
  • Significantly more patients in the RFA group compared to AAD group were free from any AF (85% vs. 71%, p = 0.004) and from symptomatic AF (93% vs. 84%, p = 0.01) at 24 months. (acc.org)
  • In the PeAF patients with CKD, ln-RHI significantly increased at 6 months after the ablation, and the change (Δ) in ln-RHI was significantly correlated with the ΔeGFR (r=0.35, p = 0.03). (elsevierpure.com)
  • The prevalence of cerebral microbleeds (CMBs) is significantly higher in patients with atrial fibrillation (AF) than in those without AF. (researchsquare.com)
  • The prevalence of CMBs is significantly higher in patients with AF than in those without AF 4 , 10 , 11 , and CMBs in patients with AF have been reported to be primarily of the lobar type 4 , 12 . (researchsquare.com)
  • Several studies have reported that the quality of life (QoL) of atrial fibrillation (AF) patients is significantly reduced compared to that of age-matched healthy control subjects. (afibbers.org)
  • The authors conclude that, "Ablation for AF significantly improves QoL irrespective of ablation success during short- and long-term follow-up. (afibbers.org)
  • The degree of QoL improvement is significantly correlated with ablation success during long-term follow-up in the questionnaires especially designed for AF and in the depression questionnaire. (afibbers.org)
  • Conclusions: In 57% of our patients, the esophagus was in direct contact with the CS, and a significantly shorter distance between the esophagus and the CS ostium was noted in these patients. (nycu.edu.tw)
  • The finding was not significantly changed in separate sensitivity analyses, the report says, including one limited to studies with low risk of bias and others excluding patients with valvular AF, interrupted OAC, heparin bridging, or subtherapeutic anticoagulation, respectively. (the-hospitalist.org)
  • RESULTS: In the non-HF group, no significant differences in recurrence after ablation were observed between the low-(n = 219), intermediate-(n = 364), and high-risk (n = 49) groups. (bvsalud.org)
  • The primary endpoint was atrial tachyarrhythmia recurrence after ablation. (biomedcentral.com)
  • Conclusions - Ectopic beats initiating PAF can originate from the non-PV areas, and catheter ablation of the non-PV ectopy has a moderate efficacy in treatment of PAF. (tmu.edu.tw)
  • Conclusions: SR restoration after ablation was associated with an improved eGFR and UACR in PeAF patients, but not PAF patients. (elsevierpure.com)
  • 001). CONCLUSIONS AND RELEVANCE: Among patients with symptomatic atrial fibrillation, catheter ablation, compared with medical therapy, led to clinically important and significant improvements in quality of life at 12 months. (duke.edu)
  • CONCLUSIONS: The FIB-4 index may be a useful predictor of AF recurrence after catheter ablation in patients with HF, particularly in those with non-PAF. (bvsalud.org)
  • Conclusions - VESA is associated with a reduction in the combined endpoint compared with the non-ablation reference group. (stanford.edu)
  • Discussion The DELETE AF trial will provide additional knowledge on long-term outcome following a structured ablation workflow, with high density mapping, advanced algorithms and local impedance technology, in an international multicentric fashion. (unav.edu)
  • After 3 months, all patients regardless of AF type and ablation outcome, showed significant improvement on all 4 generic questionnaires and in 2 of the AF specific questionnaires (changes in self-perceived impact of AF were not statistically significant). (afibbers.org)
  • The improvement in QoL continued to be statistically highly significant at 4.3 years, irrespective of AF type and ablation outcome. (afibbers.org)
  • In contrast, for selected patients under 75 years of age AF ablation can be associated with a significant improvement in outcome over a five year follow-up period. (hospitalprofessionalnews.ie)
  • Freedom from the primary outcome was 83% in the VF ablation group versus 17% in 6 non-ablation reference patients at a median of 1.0 years (IQR 0.5-1.5 years, p=0.046) follow-up. (stanford.edu)
  • The recommendation for implantable cardioverter-defibrillators to reduce the risk of sudden death or all-cause mortality in patients with NYHA class II-III symptoms and nonischemic etiology is softened slightly, moving from class I in 2016 to class IIa in 2021. (tctmd.com)
  • A total of 101 patients who underwent ablation therapy for AF were prospectively registered, and 72 patients completed the assessment with MRI 6 months after catheter ablation. (researchsquare.com)
  • Risk for the composite primary endpoint plunged 76% over a median of 18 months for those who underwent ablation. (mdedge.com)
  • At a 12-month follow-up, 9 (23%) patients had AF recurrence in the linear ablation and 8 (21%) patients in the CFAE groups. (jafib.com)
  • At a mean follow-up duration of 59±36 months, 48.3% of patients in the linear ablation group and 44.6% of patients in the CFAE group were free from AF (p=0.403). (jafib.com)
  • Furthermore, several randomized studies have produced conflicting results regarding the benefit of adding linear ablation lines, CFAE ablation, both or none. (jafib.com)
  • Hence we designed a prospective study to establish freedom from AF with combined wide area circumferential ablation and linear ablation, vs. combined wide area circumferential ablation and CFAE ablation in addition to antiarrhythmic therapy. (jafib.com)
  • Ninety-two patients with symptomatic persistent AF were randomized to PVI+ additional linear ablation group vs. PVI + physiology guided CFAE ablation. (jafib.com)
  • This invention is a circumferential ablation device assembly which is adapted to forming a circumferential conduction block in a pulmonary vein. (justia.com)
  • The assembly includes a circumferential ablation element which is adapted to ablate a circumferential region of tissue along a pulmonary vein wall which circumscribes the pulmonary vein lumen, thereby transecting the electrical conductivity of the pulmonary vein against conduction along its longitudinal axis and into the left atrium. (justia.com)
  • The circumferential ablation element includes an expandable member with a working length that is adjustable from a radially collapsed position to a radially expanded position. (justia.com)
  • More specifically, it is a circumferential ablation device assembly which is adapted to ablate a selected circumferential region of tissue along a pulmonary vein wall and thereby form a circumferential conduction block against conduction along the longitudinal axis of the pulmonary vein wall. (justia.com)
  • After PVI using the penta-spline PFA catheter, extra pulse trains were added to the posterior wall for wide antral circumferential ablation. (go.jp)
  • Among the PeAF patients, recurrent AF was identified in 41, but only transiently in 38 patients. (elsevierpure.com)
  • These catheters may be used as an alternative to medicine or other ablation catheters for treatment of recurrent symptomatic PAF. (fda.gov)
  • This study aimed to assess whether the FIB-4 index is associated with recurrent atrial fibrillation (AF) after catheter ablation in patients with and without heart failure (HF). (bvsalud.org)
  • 190 consecutive patients with hypertension and PAF were recruited. (hindawi.com)
  • We investigated consecutive patients who underwent catheter ablation for paroxysmal atrial fibrillation from January 2013 to April 2017 in two French centres. (cepia.team)
  • About 300 consecutive patients with standard indications for AF ablation will be enrolled in this study. (unav.edu)
  • Guidelines don't encourage TEE before cardioversion in patients who have been on OAC for at least 3 weeks, the group notes, and policies on TEE use before AF ablation vary widely regardless of anticoagulation status. (the-hospitalist.org)
  • If pharmacological therapy is insufficient or associated with side effects, the 2006 ACC/AHA/ESC Guidelines recommend ablation of the atrioventricular node (AVN) in conjunction with permanent pacemaker implantation to control heart rate. (ahrq.gov)
  • Results Neither baseline patient characteristics nor complication rate differed between groups. (unav.edu)
  • PV stenosis is a rare but recognized complication of catheter-based radiofrequency ablation (RFA) for atrial fibrillation (AF). (stanford.edu)
  • For patients with persistent AF treated with ablation (including one whose AF resolved with weight loss), freedom from AF off antiarrhythmic drugs at 6 months was 61% in Group 1 versus 90% in Group 2 (Fisher's Test p=0.058, OLR p=0.051) and at 12 months was 42% in Group 1 versus 81% in Group 2 (Fisher's Test p=0.050, OLR p=0.038). (medicalxpress.com)
  • During a follow-up period of 22 ± 11 months, 43 patients (63.2%) were free of antiarrhythmic drugs without AF recurrence. (tmu.edu.tw)
  • Eighty-two patients (55 men, mean age 55.9 +/- 6.1 y) underwent catheter ablation and 84 patients (58 men, mean age 57.2 +/- 5.4 years) received antiarrhythmic drug (AAD) therapy. (anti-cancers.com)
  • Since the seminal report by Dr. Michel Haïssaguerre, catheter-based ablation for atrial fibrillation (AF) has evolved and been highly effective for the elimination of atrial fibrillation (AF) compared to antiarrhythmic medications. (jafib.com)
  • OBJECTIVE: To determine whether catheter ablation is more beneficial than conventional drug therapy for improving QOL in patients with AF. (duke.edu)
  • We aim to compare the termination rate of VT between iATP and conventional ATP in patients with implantable cardioverter-defibrillators using a unique setting of different sequential orders of both ATP algorisms. (bvsalud.org)
  • RESULTS: Fifty-eight and 56 patients were enrolled in the iATP-first and conventional ATP-first groups, and 67 and 44 VTs were analyzed in each group, respectively. (bvsalud.org)
  • Conventional catheter ablation of AF is achieved by thermal (radiofrequency) or cryothermal energy. (hospitalprofessionalnews.ie)
  • 140 patients underwent a mean of 1.6 RFA procedures, and 13 patients (9%) were prescribed AAD. (acc.org)
  • Predictors and characteristics of multiple (more than 2) catheter ablation procedures for atrial fibrillation. (medscape.org)
  • Considering quality of life improvement rather than strictly success or failure of RF ablation procedures, it becomes clear that even a failed ablation may improve life quality. (afibbers.org)
  • The current study suggests that 3 weeks of OAC isn't enough for a substantial number of patients, who might be put at thromboembolic risk if TEE were to be skipped before rhythm-control procedures. (the-hospitalist.org)
  • In AF, the atria are unable to contract and this could lead to congestive heart failure in some patients, causing fluid retention in the lower legs, liver and lungs. (wustl.edu)
  • Encircling ablation lesions around the pulmonary vein os and a connecting roof line was completed with either an 8mm tip or irrigated RFA catheter. (acc.org)
  • In patients with CAD (n=44), there was no significant differences in terms of culprit vessels or number of coronary lesions. (elsevierpure.com)
  • The goal of BEAT AF is to disrupt AF ablation by achieving durable PVI with permanent, coalescent and transmural ablation lesions using Pulsed Electric Field (PEF) energy. (beat-af.com)
  • The 2014 American Heart Association (AHA)/American College of Cardiology (ACC)/Heart Rhythm Society (HRS) guidelines for the management of patients with atrial fibrillation (AF) 1 have been met with tremendous enthusiasm. (acc.org)
  • The 2011 Focused Update on the Management of Patients with Atrial Fibrillation-by the American College of Cardiology Foundation (ACCF), the AHA, and the Heart Rhythm Society (HRS)-addressed the issue of strict versus lenient rate control in patients with AF. (ahrq.gov)
  • The advantage for ablation emerged early enough that the trial, CASTLE-HTx , was halted for benefit only a year after reaching its planned enrollment, observed Christian Sohns, MD, when formally presenting the results in Amsterdam at the annual congress of the European Society of Cardiology . (mdedge.com)
  • Catheter ablation is a frequently used treatment for people with arrhythmias that can't be controlled by medication or with certain types of arrhythmias from the heart's upper chambers. (medicalxpress.com)
  • Pulmonary Vein Stenosis and Pulmonary Hypertension Following a Catheter-Based Radiofrequency Ablation for Atrial Fibrillation: A Case Report. (stanford.edu)
  • Patients were enrolled from November 2009 to April 2016 from 126 centers in 10 countries. (duke.edu)
  • Nor should an AF patient's referral to an advanced-HF center "mean that you should rush to an LVAD or transplant" before considering ablation. (mdedge.com)
  • The diagnosis of PAF or PerAF was made by the clinician according to the patient's medical history and presentation at the time of admission, regardless the actual heart rhythm when the patient was undergoing echocardiography. (biomedcentral.com)
  • 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. (medscape.org)
  • If the patient is born with only a patent foramen ovale (PFO) or a restrictive atrial septal defect (ASD), a balloon atrial septostomy or urgent surgical intervention may be required. (medscape.com)
  • The surgical care of these patients depends on the severity of the leaflet displacement and on the degree of associated right ventricular outflow tract obstruction. (medscape.com)
  • In patients with moderate-to-severe tricuspid regurgitation, the abnormal valve can be replaced with a mechanical or prosthetic valve, a surgical reconstruction, or a combination of the two. (medscape.com)
  • 1. Two recent studies find that early intervention with cryoablation may be more effective than are medications in preventing AF recurrence for patients with paroxysmal AF. (medscape.com)
  • Results from the randomized trials EARLY-AF and STOP AF showed that cryoablation was a promising first-line treatment for paroxysmal AF. (medscape.com)
  • In EARLY-AF, 303 symptomatic treatment-naive participants who had at least one episode of AF within the last 24 months or paroxysmal AF were randomly assigned to receive either an AAD or undergo cryoablation. (medscape.com)
  • The results showed AF status from enrollment to 6 months post-ablation. (medicalxpress.com)
  • Results A total of 199 patients with AAA were included in the present study. (go.jp)
  • Results in the ablation group were compared with those of the AAD group. (anti-cancers.com)
  • Results: In the ablation group, 42.7% of patients showed symptoms of depression and 37.8% showed symptoms of anxiety, which were similar to those in the AAD group. (anti-cancers.com)
  • Results can be significant, with hospitals being able to treat more AF patients, in an efficient manner. (medtechviews.eu)
  • Results - VF was induced and mapped in 6 patients (60±10 y, LVEF 46±19%) with ischemic (n=3) and nonischemic cardiomyopathy. (stanford.edu)
  • Patients were recruited for this study between January 2013 and December 2018 from the Department of Internal Medicine-Cardiovascular, the People's Hospital affiliated with Nanjing Medical University. (hindawi.com)
  • A new research paper titled "Cardiovascular events and death after catheter ablation in very old patients with nonvalvular atrial fibrillation" has been published inAging. (medicalxpress.com)
  • Gender-related differences in risk of cardiovascular morbidity and all-cause mortality in patients hospitalized with incident atrial fibrillation without concomitant diseases: A nationwide cohort study of 9519 patients. (medscape.org)
  • Background: Cardiovascular events in patients with atrial fibrillation (AF) can be lowered by catheter ablation. (elsevierpure.com)
  • The difference in the primary endpoint "in this severely sick cohort of advanced, end-stage heart failure patients," he said, was driven mostly by fewer deaths, especially cardiovascular deaths, in the ablation group. (mdedge.com)
  • Another electrophysiologist, Dhiraj Gupta, MD , noted the potential for bias against the AAD arm in the STOP AF trial since more than 15% of participants in that group crossed over to the ablation group and crossover was included in the treatment success endpoint. (medscape.com)
  • AAD could be used during the first 3 months post ablation. (acc.org)
  • After a mean of nine months, 54 patients (36%) crossed over to RFA. (acc.org)
  • During 23 ± 13 months of follow-up, none of the 16 patients with slow-pathway catheter ablation had recurrence of PSVT. (tmu.edu.tw)
  • Brain MRI, including diffusion-weighted imaging (DWI) and susceptibility-weighted imaging (SWI), were examined at 1-3 days (baseline) and 6 months after catheter ablation. (researchsquare.com)
  • Post-ablation, all patients will be monitored with ambulatory event monitoring, starting within 30 days post-ablation to proactively detect and manage any recurrences within the 90-day blanking period, as well as Holter monitoring at 3, 6, 9, and 12 months post-ablation. (unav.edu)
  • PACS and LAEF initially decreased 1-day following ablation but partially recovered within 3 months in PAF patients, with a similar trend in the PerAF patients. (biomedcentral.com)
  • After median 24 months follow-up, 68 (47%) patients had recurrence. (biomedcentral.com)
  • Fourteen months later, the patient was diagnosed with cerebral infarction. (authorea.com)
  • Oral anticoagulation was discontinued after 6 months in all patients without AF recurrence provided their CHADS2 score was below 2. (afibbers.org)
  • Programmed electrical stimulation could induce a single AV node echo beat in 12 patients, double echo beats in 4 patients and none in 11 patients at baseline or during isoproterenol infusion. (tmu.edu.tw)
  • Fifty-nine patients (86.8%) showed embolic microinfarctions on baseline DWI immediately after catheter ablation. (researchsquare.com)
  • Prior to the ablation, all patients filled out 7 detailed questionnaires designed to provide a quantitative estimate of their baseline QoL. (afibbers.org)
  • The CHA 2 DS 2 -VASc score is now recommended over the CHADS 2 score for determination of thromboembolic risk in non-valvular AF (Figure 1), largely because of the limited discrimination the CHADS 2 score offers for patients with intermediate risk (i.e. (acc.org)
  • Now with the CHA 2 DS 2 -VASc score, which is a much more sensitive scoring system, a lot more patients will end up having anticoagulation recommended. (stopafib.org)
  • Now my preference in CHA 2 DS 2 -VASc 1, particularly patients with significant hypertension [high blood pressure], would be to err on the side of anticoagulation. (stopafib.org)
  • The CHA 2 DS 2 -VASc score contains more risk factors and has a greater range of points, thus switching to the CHA 2 DS 2 -VASc score will increase the number of patients eligible for anticoagulation. (acc.org)
  • For those patients to be treated with anticoagulation, the guidelines recommend either warfarin or one of the novel oral anticoagulants (NOACs). (acc.org)
  • For patients with "intermediate" risk (CHA 2 DS 2 -VASc score of 1), the option of anticoagulation, aspirin monotherapy, or no therapy is left to a consensus decision between the provider and patient. (acc.org)
  • Prior to consideration of ablation, patients with AF need to be assessed for anticoagulation. (hospitalprofessionalnews.ie)
  • Peri-procedural management of patients taking oral anticoagulants. (medscape.org)
  • We sought to determine whether the post-procedural changes in LA function impact the risk of recurrence following AF ablation. (biomedcentral.com)
  • standardising appointments, enhancing patient education, conducting remote screening and standardised procedural workflows. (medtechviews.eu)
  • Elevated plasma vitamin B12 concentrations were identified as predictors of mortality in patients with oncologic, hepatic and renal diseases, and in elderly and critically ill medical patients. (mdpi.com)
  • The association between vitamin B12 concentrations and in-hospital mortality in adult patients at nutritional risk has not been assessed. (mdpi.com)
  • They specifically define a more mildly reduced EF group, and they explicitly state: "To date, no treatment has been shown to reduce mortality and morbidity in patients with HFpEF. (tctmd.com)
  • The soluble guanylate cyclase stimulator gets at IIb recommendation, meaning it "may be considered in patients in NYHA class II-IV who have had worsening HF despite treatment with an ACE inhibitors (or ARNI), a beta-blocker, and an MRA to reduce the risk of CV mortality or HF hospitalization. (tctmd.com)
  • It worsens heart failure and increases mortality in patients with myocardial infarction, and is an independent risk factor for death. (aafp.org)