AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureHumanitiesInformation ScienceHealth CareGeographicals
OsteoarthritisOsteoarthritis, KneeOsteoarthritis, HipKnee JointCartilage, ArticularOsteoarthritis, SpineHand JointsArthralgiaMenisci, TibialOsteophytePain MeasurementInjections, Intra-ArticularPainSynovial FluidHip JointChondrocytesFinger JointSynovial MembraneTibiaArthroplasty, Replacement, KneeRange of Motion, ArticularSeverity of Illness IndexStifleFemurArthritis, RheumatoidKnee InjuriesWeight-BearingViscosupplementationAnterior Cruciate LigamentKneeHyaluronic AcidViscosupplementsCartilage DiseasesPatellaBone MalalignmentArthrographyAnti-Inflammatory Agents, Non-SteroidalMatrilin ProteinsCartilageTreatment OutcomeOsteotomyJointsCollagen Type IISynovitisArthroplasty, Replacement, HipDisease ProgressionFemur HeadCarpometacarpal JointsMatrix Metalloproteinase 13HandCartilage Oligomeric Matrix ProteinDisability EvaluationChondrocalcinosisGaitMagnetic Resonance ImagingGlucosamineArthroplasty, ReplacementArthroscopyBiomechanical PhenomenaJoint InstabilityJoint Deformities, AcquiredJoint DiseasesPatellofemoral JointAggrecansArthritisExercise TherapyReproducibility of ResultsDiclofenacShoesArthroplastyQuadriceps MusclePain ManagementArthritis, ExperimentalGrowth Differentiation Factor 5Extracellular Matrix ProteinsFollow-Up StudiesAcetabulumHip Dislocation, CongenitalMuscle StrengthAnkle JointRecovery of FunctionWalkingProteoglycansLameness, AnimalActivities of Daily LivingKnee ProsthesisBiological MarkersDouble-Blind MethodMetacarpal BonesProspective StudiesHip InjuriesThumbChondroitin SulfatesBone Marrow DiseasesNaproxenQuestionnairesHarpagophytumRisk FactorsCase-Control StudiesMatrix Metalloproteinase 3
Rheumatoid arthritisCartilageBackground OsteoarthritisCause of osteoarthritisAdvanced osteoarthritis of the kneeDegenerativeData from the Osteoarthritis InitiativeManagement of osteoarthritisSymptomsSymptomatic kneePeople with knee osteoarthritisLikely to develop osteoarthritisAmong patients with osteoarthritisClinicalRadiographicGoal of treating osteoPrevalenceTreatments for osteoarthritisMethodsMulticenterChronicFINDINGSRheumatologyTest for osteoarthritisSeverity of osteoarthritisLink between osteoarthritisDevelopment of osteoarthritisAssociation between osteoarthritisCauses osteoarthritisAffectsInitiativeRelieveSevereWOMACMiddle AgedOutcomesForm of arthritisBrigham and WomeJointClassificationJointsSystematicTreatmentAcupunctureEfficacySignificantlyInflammationExercise2022StudyNIAMSComplementaryCommonDiagnosisProgressesInactivityPainfulDisparitiesPrimary careCohortManagingPlaceboOccurs
Rheumatoid arthritis5
  • While recent scientific advances have yielded highly effective disease-modifying therapies for rheumatoid arthritis, no such therapies exist for osteoarthritis. (nih.gov)
  • Diclofenac sodium and misoprostol delayed-release tablets are a combination of diclofenac sodium, a non-steroidal anti-inflammatory drug, and misoprostol, a prostaglandin-1 (PGE1) analog, indicated for the treatment of signs and symptoms of osteoarthritis or rheumatoid arthritis in adult patients at high risk of developing NSAID-induced gastric and duodenal ulcers and their complications. (nih.gov)
  • In contrast to rheumatoid arthritis, in osteoarthritis the joints do not become hot or red. (wikipedia.org)
  • Quantitative pain assessment for routine care of rheumatoid arthritis patients, using a pain scale based on activities of daily living and a visual analog pain scale. (sma.org)
  • In doing so, they assert that the results from the rheumatoid arthritis analyses support the validity of the findings regarding osteoarthritis and mortality. (cdc.gov)
Cartilage19
Background Osteoarthritis1
  • RESEARCH OBJECTIVES Background Osteoarthritis (OA) is a common, costly and potentially disabling disease of joints that affects more than 16 million Americans at an economic cost in excess of $8 billion, annually. (nih.gov)
Cause of osteoarthritis4
Advanced osteoarthritis of the knee2
Degenerative5
  • Osteoarthritis of the knee (or "knee OA" for short) is a degenerative condition of the knee joint. (ottobock.com)
  • Also known as degenerative joint disease or age-related arthritis , osteoarthritis is more likely to develop as people get older. (webmd.com)
  • Osteoarthritis (OA) is a degenerative joint disease that should ideally be detected earlier on in the disease process when treatments will likely be more effective. (stanford.edu)
  • Osteoarthritis (OA) is the most common degenerative joint disease, of which the pathogenesis is inadequately understood. (nordicbioscience.com)
  • Osteoarthritis is a degenerative condition in dogs that will get more severe over time. (woburnanimalhospital.com)
Data from the Osteoarthritis Initiative1
Management of osteoarthritis1
Symptoms16
  • Patients with chronic pain due to OA of the knee or the hip who were treated with acupuncture in addition to routine care showed significant improvements in symptoms and quality of life compared with patients who received routine care alone," the authors state. (medscape.com)
  • Finset A. Clinician-patient interaction and health outcome: a potential impact on symptoms and quality of life in patients with pain? (physiciansweekly.com)
  • What are the symptoms of osteoarthritis? (nih.gov)
  • Due to its chronic nature and the lack of effective disease modifying therapies a range of biobehavioral, dietary, pharmacologic and complementary and alternative (CAM) therapies are used by patients to reduce OA symptoms, pain, and improve function and quality of life. (nih.gov)
  • Second, participant s at baseline with worse patient-centered outcomes and knee osteoarthritis are more likely to utilize CAM therapies in an attempt to alleviate symptoms. (nih.gov)
  • CAM therapy at baseline will be greater in those participants with more severe symptoms (frequency and intensity) and severity of radiographic osteoarthritis as well as other socio-demographic factors (gender, race). (nih.gov)
  • Inform patients of warning signs and symptoms of hepatotoxicity. (nih.gov)
  • Trauma to the joint: Symptoms of osteoarthritis may appear years after a trauma to the shoulder joint (e.g., a broken bone or dislocation). (brighamandwomens.org)
  • The following are common symptoms of shoulder osteoarthritis symptoms. (brighamandwomens.org)
  • this occurred when symptoms of OA were normalised as part of everyday life and when patients were reassured when not seeking reassurance. (whiterose.ac.uk)
  • GPs subconsciously made assumptions that patients did not prioritise OA and that symptoms raised late in the consultation were not troublesome. (whiterose.ac.uk)
  • Your vet will be sure to recommend the best level of exercise to help relieve your dog's osteoarthritis symptoms. (woburnanimalhospital.com)
  • In some cases when joint damage is severe your vet may recommend surgery to help alleviate symptoms and slow the progression of your dog's osteoarthritis. (woburnanimalhospital.com)
  • No patient taking MS-sNT as directed experienced withdrawal symptoms. (johnshopkins.edu)
  • Only half of patients with pathologic changes of osteoarthritis have symptoms. (msdmanuals.com)
  • In studies of the prevalence of osteoarthritis, those that relied on radiographic data for the operational definition of osteoarthritis produced the highest prevalence estimates whereas studies that used self-reported data or symptoms yielded comparable prevalence estimates. (cdc.gov)
Symptomatic knee6
  • Because little is known about determinants of ROM, the objective of the present study was to explore the association between demographic, articular, and clinical factors and ROM in patients with early symptomatic knee and/or hip OA. (eur.nl)
  • Results: In patients with early symptomatic knee OA, osteophytosis, bony enlargement, crepitus, pain, and higher BMI were associated with lower knee flexion. (eur.nl)
  • This study was performed to compare the efficacy and safety of ozone injections, PRP (platelet rich plasma) injections and combined ozone plus PRP injections in patients with symptomatic knee OA. (uv.es)
  • The prevalence of symptomatic knee and distal interphalangeal joint osteoarthritis in the urban population of Antalya, Turkey. (uv.es)
  • The efficacy of platelet-rich plasma in the treatment of symptomatic knee osteoarthritis: a systematic review with quantitative synthesis. (uv.es)
  • Our findings show that pain in the low back, foot and elbow may be associated with greater knee pain, confirming that symptomatic knee [osteoarthritis] rarely occurs in isolation," lead researcher Pradeep Suri, M.D., said. (massagemag.com)
People with knee osteoarthritis5
  • Nemati D, Keith N, Kaushal N. Investigating the Relationship Between Physical Activity Disparities and Health-Related Quality of Life Among Black People With Knee Osteoarthritis. (cdc.gov)
  • Our findings highlight racial health disparities that exist in psychological, behavioral, and well-being variables among people with knee osteoarthritis. (cdc.gov)
  • Health care providers should be aware of discrepancies in physical activity participation that might affect health-related quality of life among people with knee osteoarthritis. (cdc.gov)
  • Effectiveness of neuromuscular electrical stimulation training combined with exercise on patient-reported outcomes measures in people with knee osteoarthritis: A systematic review and meta-analysis. (bvsalud.org)
  • This study examined the effectiveness of neuromuscular electrical stimulation (NMES) added to the exercise or superimposed on voluntary contractions on patient-reported outcomes measures (PROMs) in people with knee osteoarthritis (OA). (bvsalud.org)
Likely to develop osteoarthritis1
Among patients with osteoarthritis1
  • Racial differences in health care utilization among patients with osteoarthritis. (sma.org)
Clinical16
  • These results indicate that acupuncture plus routine care is associated with marked clinical improvement in patients with chronic OA-associated pain of the knee or hip. (thecamreport.com)
  • Scholars@Duke publication: Clinical hip tests and a functional squat test in patients with knee osteoarthritis: reliability, prevalence of positive test findings, and short-term response to hip mobilization. (duke.edu)
  • The results suggest that a template- or population-based approach, which is much faster than fully subject-specific, could be applied as a clinical prediction tool for osteoarthritis. (springer.com)
  • HR-QOL has been proven to be disproportionately lower among Black people compared with their White counterparts across several clinical samples, including people with dementia (4), cancer patients (5,6), and stroke patients (7), and this pattern is consistent among people with knee OA (8-10). (cdc.gov)
  • Because of the chronic nature of the disease and variable clinical outcomes, a better understanding of the relationship between various measures of clinically relevant or patient-centered outcomes - pain, stiffness, reduced function, use of analgesics, disability, quality of life and composite scores accounting for these and other clinically relevant outcomes are needed. (nih.gov)
  • Characterize patient-centered outcomes (pain, loss of function, disability, quality of life) in OAI including developing a clinical severity score using principal component analysis (PCA) to define an overall clinical severity score both at baseline and changes longitudinally over six years of follow-up. (nih.gov)
  • The OAM and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) seeks, with this RFA, to initiate a clinical trial of acupuncture for the treatment of osteoarthritis (OA) of the knee by experienced investigators who have the unique technical capabilities to study acupuncture in a clinical setting. (nih.gov)
  • Clinical hold follows reports that tanezumab-treated patients require joint replacement. (genengnews.com)
  • Pfizer announced the immediate suspension of clinical trials evaluating its Phase III-stage chronic pain drug tanezumab in patients with osteoarthritis (OA). (genengnews.com)
  • The clinical hold requested by FDA follows what Pfizer describes as a small number of reports that osteoarthritis patients receiving the mAb candidate experienced worsening of their disease and needed joint replacements. (genengnews.com)
  • As a result of the clinical hold all patients in the ongoing Phase III osteoarthritis program for tanezumab will have their treatment with the active drug stopped, and no new patients will be enrolled. (genengnews.com)
  • FDA has requested that the firm present an assessment of the potential implications of the adverse osteoarthritis-related events for other tanezumab clinical trials within the week. (genengnews.com)
  • We sought to investigate the relative importance of perceived service-related and clinical need attributes in the decision to consult a primary care physician for painful osteoarthritis. (bmj.com)
  • This study demonstrated that SKI 306X, a new herbal anti-arthritic agent provided clinical efficacy in patients with osteoarthritis. (ewha.ac.kr)
  • Rapid destructive osteoarthritis: clinical, radiographic, and pathologic features. (sma.org)
  • Shao-Hsien Liu, MPH, trained as a physical therapist in Taiwan and is currently studying the application of advanced epidemiologic methods to clinical questions in osteoarthritis. (cdc.gov)
Radiographic2
  • The radiographic appearance of PGOA is indistinguishable from that of nonfamilial primary osteoarthritis, although PGOA typically progresses relatively rapidly and has a severe appearance on images. (medscape.com)
  • We found significantly higher levels of ColX in patients with KL score 2 compared to patients with no radiographic evidence of OA (KL0) (p = 0.04). (nordicbioscience.com)
Goal of treating osteo2
  • The goal of treating osteoarthritis is to ease your pain, help you move better, and stop it from getting worse. (nih.gov)
  • The main goal of treating osteoarthritis of the hip is to improve the person's mobility (ability to get around) and lifestyle. (webmd.com)
Prevalence8
  • Cardiovascular disease prevalence in patients with inflammatory arthritis, diabetes mellitus and osteoarthritis: a cross-sectional study in primary care. (nivel.nl)
  • We sought to determine the prevalence rate of non-fatal cardiovascular disease (CVD) in inflammatory arthritis, diabetes mellitus and osteoarthritis (non-systemic inflammatory comparator) compared to controls, in primary care. (nivel.nl)
  • RESULTS: CVD prevalence rates were significantly higher in inflammatory arthritis, diabetes mellitus and osteoarthritis compared with controls. (nivel.nl)
  • The prevalence of OA increases with age and it represents the major problem for functional impairment in older patients. (uv.es)
  • OBJECTIVES: Primary purposes of this study were to examine the short-term effect of hip mobilizations on pain and range of motion (ROM) measurements in patients with knee osteoarthritis (OA) and to determine the prevalence of painful hip and squat test findings in both patients with knee OA and asymptomatic subjects. (duke.edu)
  • Calcium pyrophosphate deposition (CPPD) disease prevalence is similar to gout and osteoarthritis (OA), yet CPPD outcomes research greatly lags behind these other forms of arthritis. (qxmd.com)
  • This survey demonstrated the high prevalence of CAM use (especially herbal remedies) in paediatric patients with hepatogastrointestinal diseases. (who.int)
  • Among paediatric medical conditions, chronic gastrointestinal complaints and diseases such as chronic constipation, chronic abdominal pain and failure to thrive, along with patients with chronic hepatic diseases such as cirrhosis and hepatic transplant patients, are also disposed to high prevalence of CAM use (11). (who.int)
Treatments for osteoarthritis1
Methods4
  • METHODS: Data on CVD morbidity (ICPC codes K75 (myocardial infarction), K89 (transient ischemic attack), and/or K90 (stroke/cerebrovascular accident)) from patients with inflammatory arthritis (n = 1,518), diabetes mellitus (n = 11,959), osteoarthritis (n = 4,040) and controls (n = 158,439) were used from the Netherlands Information Network of General Practice (LINH), a large nationally representative primary care based cohort. (nivel.nl)
  • Methods An observational study was conducted in General Practices in the UK using video recorded real-life consultations of unselected patients and their GPs. (whiterose.ac.uk)
  • Patients and Methods: This phase 3 study had an enriched-enrollment, randomized-withdrawal, double-blind, multicenter design. (johnshopkins.edu)
  • Review patient evaluation methods that can be used to identify the most appropriate treatment options for chronic pain. (cdc.gov)
Multicenter2
  • Data were from the Osteoarthritis Initiative, a multicenter longitudinal study that collected data from people with knee OA. (cdc.gov)
  • This research, conducted by researchers from Harvard Medical School , New England Baptist Hospital and Spaulding Rehabilitation Hospital in Boston, Massachusetts, used data provided by individuals from the Osteoarthritis Initiative, a multicenter, population-based observational cohort study of osteoarthritis of the knee, the press release noted. (massagemag.com)
Chronic9
  • In recent years, patients have turned increasingly to acupuncture to relieve the chronic pain associated with OA. (medscape.com)
  • Led by Claudia M. Witt of the University Medical Center in Berlin, Germany, researchers conducted a randomized, controlled trial of a large number of patients with chronic pain due to OA of the knee or hip. (medscape.com)
  • The authors conclude that "the present results show that, in patients with chronic pain due to OA of the knee or hip who were receiving routine primary care, addition of acupuncture to the treatment regimen resulted in a clinically relevant and persistent benefit. (medscape.com)
  • Knee osteoarthritis (KOA) is one of the leading causes of chronic pain and disability worldwide, affecting over 30% of older adults and represents a major global health and economic burden to individuals and society. (nih.gov)
  • OA is a chronic and disabling joint disease with limited evidence-based pharmacological treatment options available that improve outcomes for patients safely. (nih.gov)
  • The antibody is also undergoing Phase II trials for other chronic pain conditions, and any osteoarthritis patients enrolled in these studies will also have treatment with tanezumab halted, Pfizer notes. (genengnews.com)
  • MS-sNT), which contain morphine sulfate pellets with a sequestered naltrexone core, in treating patients with chronic, moderate-to-severe osteoarthritis (hip or knee) pain. (johnshopkins.edu)
  • Conclusion: MS-sNT provided effective analgesia in patients with chronic, moderate-to-severe osteoarthritis pain, with a safety profile typical of morphine-containing products. (johnshopkins.edu)
  • It is also commonly used in patients with chronic hepatic conditions such as cirrhosis and in hepatic transplant patients. (who.int)
FINDINGS2
  • Patients with knee OA and painful-hip and squat test findings received hip mobilizations. (duke.edu)
  • CONCLUSIONS: Patients experienced increases in ROM, decreased pain, and fewer subjects had painful test findings immediately following a single session of hip mobilizations. (duke.edu)
Rheumatology3
  • 120 patients were diagnosed of OA according to the criteria of the American College of Rheumatology and included into this study. (uv.es)
  • BIRD has just published a new series of podcasts to add to our growing podcast library for rheumatology patients. (birdbath.org.uk)
  • Alternative medicine use by rheumatology patients in a universal health care setting. (sma.org)
Test for osteoarthritis1
Severity of osteoarthritis1
Link between osteoarthritis2
  • A recent study conducted by researchers from Harvard Medical School and published in the peer-reviewed medical journal, Arthritis Care and Research, focused on the link between osteoarthritis and milk consumption. (txortho.com)
  • report on their careful analysis which adds to the growing literature evaluating the link between osteoarthritis and time to death. (cdc.gov)
Development of osteoarthritis3
  • The development of osteoarthritis is correlated with a history of previous joint injury and with obesity, especially with respect to knees. (wikipedia.org)
  • Changes in sex hormone levels may play a role in the development of osteoarthritis, as it is more prevalent among post-menopausal women than among men of the same age. (wikipedia.org)
  • Repetitive stresses: People whose jobs require repeated lifting or pushing, such as activities performed during manual labor, subject their shoulders to stresses that can accelerate the development of osteoarthritis. (brighamandwomens.org)
Association between osteoarthritis1
Causes osteoarthritis3
Affects6
Initiative1
  • The Osteoarthritis Initiative is large epidemiologic study with multiple patient-centered outcomes assessed yearly in subjects at high risk or having already developed knee OA as defined by fixed flexion radiographs at baseline. (nih.gov)
Relieve2
Severe8
  • Patients that have failed Phase I treatment will be provided with an opioid for severe pain management, if appropriate, allowing the study team to examine the opioid-sparing effects of these procedures in a subset of participants. (nih.gov)
  • The osteoarthritis patients that were recruited presented moderate to severe pain. (bioiberica.com)
  • We analyzed zygapophyseal joints from patients with AS and osteoarthritis (OA) undergoing spinal surgery for rigid hyperkyphosis (AS) or radiculopathy caused by severe OA. (jrheum.org)
  • Zygapophyseal joints were obtained from 17 AS patients who had severe kyphosis with advanced ankylosis in the lumbar spine and who underwent surgery for polysegmental correction of rigid hyperkyphosis. (jrheum.org)
  • Avoid in patients with severe heart failure unless benefits are expected to outweigh risk of worsening heart failure. (nih.gov)
  • CPPD patients had significantly worse WOMAC stiffness scores than patients with mild OA, and significantly better WOMAC function scores than patients with severe OA. (qxmd.com)
  • Objectives Some patients spend years with painful osteoarthritis without consulting for it, including times when they are experiencing persistent severe pain and disability. (bmj.com)
  • Overall, those who received the supplements had no significant improvement in knee pain or function, although the investigators saw evidence of improvement in a small subgroup of patients with moderate-to-severe pain who took glucosamine and chondroitin together. (nih.gov)
WOMAC3
  • The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and a health-related quality of life survey (Short Form 36) were used to measure outcomes when the study began and at three and six months. (medscape.com)
  • While Western Ontario and McMaster Universities Osteoarthritis index (WOMAC) and Knee Injury and Osteoarthritis Outcomes Score (KOOS) summary scales have been developed they rely exclusively on subjective outcomes, and are highly inter-correlated making a summary score of questionable value. (nih.gov)
  • Secondary efficacy measures included the remaining BPI scores and Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index. (johnshopkins.edu)
Middle Aged1
  • Osteoarthritis can happen at any age, but the chance of getting it increases in middle-aged adults and older. (nih.gov)
Outcomes6
  • Aim 2 will determine if genicular nerve radiofrequency ablation (RFA) or intra-articular injection of hyaluronic acid and steroid are more effective in improving outcomes than local anesthetic nerve block or SOC and help establish the role of these interventional treatments in the overall management of pain in KOA patients. (nih.gov)
  • Despite their wide use, relatively few CAM therapies have been tested adequately with appropriate study designs to assess their effectiveness in improving patient-centered outcomes. (nih.gov)
  • When studying the effectiveness of biobehavioral, dietary, pharmacologic and CAM therapies on improving patient centered outcomes related to knee osteoarthritis several analytic issues arise when evaluating epidemiological data. (nih.gov)
  • First no validated composite outcome measure has been developed that accounts for the full impact of knee osteoarthritis on patient-centered outcomes. (nih.gov)
  • Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis. (qxmd.com)
  • Differential Item Functioning (DIF) examined bias in respondent subgroups and correlations tested relationships between PAM-13 and other patient-reported outcomes. (biomedcentral.com)
Form of arthritis5
  • Osteoarthritis (OA) is the most common form of arthritis and some joints are effected more than others. (uv.es)
  • Knee osteoarthritis (OA) is the most common form of arthritis, which is a leading cause of disability. (cdc.gov)
  • Osteoarthritis (OA), the most common form of arthritis, is a slowly progressing disease characterized clinically by pain, deformity, and loss of function. (nih.gov)
  • Osteoarthritis is the most common form of arthritis, affecting about 237 million people or 3.3% of the world's population, as of 2015. (wikipedia.org)
  • This challenges current guidelines from Europe and America that topical NSAIDS are an effective treatment for osteoarthritis, the most common form of arthritis. (news-medical.net)
Brigham and Wome2
  • Patients with CPPD were recruited from Brigham and Women's Hospital, 2018-2022. (qxmd.com)
  • Our world-renowned Brigham and Women's Hospital Orthopaedic & Arthritis Center team is dedicated to providing the most advanced care for all bone and joint conditions to reduce pain, increase mobility and improve quality of life for our patients. (brighamandwomens.org)
Joint13
  • The goals of knee osteoarthritis (OA) treatment are to improve health-related quality of life and limit the progression of joint damage. (physiciansweekly.com)
  • Osteoarthritis patients' perceptions of "appropriateness" for total joint replacement surgery. (physiciansweekly.com)
  • Health benefits of joint replacement surgery for patients with osteoarthritis: prospective evaluation using independent assessments in Scotland. (bmj.com)
  • Now, a larger study in Germany has concluded that after 3 months, the 357 patients with OA of the knee or hip who were randomly assigned to acupuncture had significant improvement in pain, disability, joint stiffness, and in their quality of life compared to the 355 patients who did not receive acupuncture treatment. (thecamreport.com)
  • Computational finite element (FE) models of the knee joint are able to offer a quantitative estimation about risks for the onset and development of knee osteoarthritis (OA) based on mechanical signals experienced by tissues. (springer.com)
  • How Does Osteoarthritis Affect the Hip Joint? (webmd.com)
  • There is no single test for diagnosing osteoarthritis , but often it is diagnosed by an abnormal X-ray that shows characteristic features such as narrowing of the joint and spurring of the joint margins. (webmd.com)
  • Osteoarthritis is believed to be caused by mechanical stress on the joint and low grade inflammatory processes. (wikipedia.org)
  • Osteoarthritis can cause a crackling noise (called "crepitus") when the affected joint is moved, especially shoulder and knee joint. (wikipedia.org)
  • Osteoarthritis is the most common cause of a joint effusion of the knee. (wikipedia.org)
  • Osteoarthritis (OA) is the most com-mon adult joint disease and accounts for significant morbidity burdens among U.S. civilian and military populations. (health.mil)
  • Osteoarthritis, the most common joint disorder, often becomes symptomatic in the 40s and 50s and is nearly universal (although not always symptomatic) by age 80. (msdmanuals.com)
  • Below age 40, most large-joint osteoarthritis occurs in men and often results from trauma or anatomic variation (eg, hip dysplasias). (msdmanuals.com)
Classification1
  • 2. Altman R, Asch E. Development of criteria for the classification and reporting of osteoarthritis. (sma.org)
Joints7
Systematic2
  • Two systematic reviews have evaluated the effects of self-management interventions that included OA patients. (biomedcentral.com)
  • The potential for systematic differences in who was classified as having osteoarthritis to those who may have osteoarthritis, but do not seek care, exists. (cdc.gov)
Treatment17
  • They also suggest that in reality, few OA patients use acupuncture as the sole treatment and that a lack of information about how well it works has probably meant that acupuncture is an undervalued treatment option that could be an important element of a multidisciplinary approach to treating OA. (medscape.com)
  • Aim 1 will evaluate the effectiveness of individual and combined online cognitive behavioral therapy (PainTRAINER) and pharmacologic treatment (duloxetine) in improving pain and function for KOA patients compared to standard of care. (nih.gov)
  • The knowledge gained will contribute to the development of translatable therapeutic strategies for the treatment of patients with KOA pain that will lead to opioid sparing effects. (nih.gov)
  • Treatment of osteoarthritis of the knee: evidence-based guideline, 2nd edition. (physiciansweekly.com)
  • This fact is especially relevant because this drug has not been proved to be efficient for the treatment of osteoarthritis. (bioiberica.com)
  • Patients' pain were recorded at 2 weeks and 4 weeks of treatment and also 2 weeks after the treatment ended. (glucosamine-arthritis.org)
  • Non-surgical treatment with oral drugs is not suitable for many patients suffering from gastric disorders, high blood pressure or different heart diseases. (uv.es)
  • Preparation procedures and evaluation of PRP injections in the treatment of knee osteoarthritis. (uv.es)
  • Comparison between intra- articular ozone and placebo in the treatment of knee osteoarthritis: a randomized, double-blinded, placebo-controlled study. (uv.es)
  • Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals. (nih.gov)
  • CPPD patients reported significantly greater unmet treatment need than gout patients (p=0.04). (qxmd.com)
  • Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs. (qxmd.com)
  • Topical NSAIDS were superior to placebo in relieving pain due to osteoarthritis only in the first two weeks of treatment. (news-medical.net)
  • Patients were randomized to four treatment groups: placebo, 200 mg, 400 mg and 600 mg of SKI 306X t.i.d. (ewha.ac.kr)
  • Variation in perceptions of treatment and self-care practices in elderly with osteoarthritis: a comparison between African American and white patients. (sma.org)
  • Managing your dog's weight will be a key element of their treatment for osteoarthritis. (woburnanimalhospital.com)
  • Total hip replacement (THR) is an up-to-date method of treatment for dysplastic hip patients. (rsu.lv)
Acupuncture7
  • Each patient was followed for a total of six months and the control group received acupuncture during the last three months of their study period. (medscape.com)
  • Furthermore, patients in the control group who received acupuncture only after three months showed similar improvements at six months. (medscape.com)
  • In addition, acupuncture features close patient-provider relationships that involve enhanced interaction and communication, which can be beneficial in managing OA. (medscape.com)
  • They state that the study was limited in that the patient informed consent process was unclear and there were some patient characteristics that were not described, such as whether patients had previously tried acupuncture and what their experience was. (medscape.com)
  • In 2004, Dr. Brian Berman at the University of Maryland School of Medicine in Baltimore followed 570 people with osteoarthritis of the knee for 6 months, making it the longest and largest study of acupuncture to that time. (thecamreport.com)
  • By week 8, the acupuncture group had better function than either the patients treated with sham acupuncture or the group that participated in an educational program developed by the Arthritis Foundation. (thecamreport.com)
  • This entry was posted on Wednesday, November 1st, 2006 at 8:48 PM and is filed under Acupuncture/ pressure , Osteoarthritis . (thecamreport.com)
Efficacy2
  • He added that "in these patients it would be preferable to consider the use of other drugs, such as chondroitin sulfate, which are specific against osteoarthritis, for they have a proved efficacy and a high security profile. (bioiberica.com)
  • A double-blind, controlled study was performed to evaluate the efficacy and safety of SKI 306X with placebo in 96 patients with classical osteoarthritis of the knee. (ewha.ac.kr)
Significantly6
  • Subjects with knee osteoarthritis had significantly higher coactivity than age-matched healthy adults and young adults and healthy adults had more coactivity than young adults regardless the type of coactivity ratio. (unboundmedicine.com)
  • Trabecular thickness was significantly lower in patients with AS compared to OA (p = 0.01). (jrheum.org)
  • 0.001) and OC+ (p = 0.002), OPG+ (p = 0.003), and RANKL+ osteoblasts (p = 0.03) in AS patients was also significantly lower than in OA patients. (jrheum.org)
  • 0.05) osteoblasts were significantly lower compared to AS patients. (jrheum.org)
  • Patients who received a newer prosthesis similar to the Miller-Galante knee design showed significantly better Knee Society function scores than patients who had a long-used prosthesis to which it was compared. (yoummd.com)
  • We developed a novel assay, C-Col10, for measurement of chondrocyte hypertrophy and found its levels significantly elevated in OA patients with KL score of 2, and also in OA patients with above normal hsCRP levels. (nordicbioscience.com)
Inflammation3
  • Erosive (ie, inflammatory) osteoarthritis is a form of primary osteoarthritis marked by a greater degree of inflammation, with erosive abnormalities and, in some cases, osseous ankylosis. (medscape.com)
  • Associations between serum levels of the three biomarkers (log transformed) were analyzed by Pearson's correlation and differences in C-Col10 levels between patients with high and low levels of inflammation measured by hsCRP were analyzed by ANOVA. (nordicbioscience.com)
  • Effective inflammation and pain management is possible for your canine osteoarthritis patients. (veterinarypracticenews.com)
Exercise5
  • Move More" and "Exercise Rx for Osteoarthritis. (unc.edu)
  • This online article written for patients with arthritis describes how to safely start an exercise program, select the right type of activity, and create a sustainable exercise plan. (unc.edu)
  • However exercise, including running in the absence of injury, has not been found to increase the risk of knee osteoarthritis. (wikipedia.org)
  • Although it may seem counterintuitive exercise is essential for dogs with osteoarthritis. (woburnanimalhospital.com)
  • And describe the role of patient beliefs and expectations and value of exercise, education, and non-opioid drug treatments and the management of muscular skeletal pain complaints. (cdc.gov)
20221
Study12
  • In a retrospective cohort study of Health Maintenance Organization enrollees, 1405 patients with OA aged 45 and older who received a new prescription for one of 4 NSAID were followed for 12 months. (nih.gov)
  • In a cross-sectional study, subjects with grade II knee osteoarthritis (n = 26), healthy age- and gender-matched (n = 20) and healthy, young adults (n = 20) performed three activities of daily living. (unboundmedicine.com)
  • These are the main conclusions of the EMARTRO study (Estudio para evaluar la coMorbilidad en pacientes afectos de ARTrosis sintomática de Rodilla) which involved 1,371 patients (both from rural and urban environments) and 61 primary care physicians from 13 different Spanish regions. (bioiberica.com)
  • We wanted to take a current picture of osteoarthritis in Spain, and this is why we gave our support to this study from the primary care sector, the medical specialty most often dealing with these patients. (bioiberica.com)
  • A study was done in China involving people with osteoarthritis of the knee to determine the effectiveness of glucosamine versus ibuprofen. (glucosamine-arthritis.org)
  • This study provides some evidence of adequate person and item reliability, unidimensionality, and construct validity to support the use of PAM-13 to measure patient activation in people living with hip and knee OA. (biomedcentral.com)
  • A large National Institutes of Health (NIH) study, called the Glucosamine/chondroitin Arthritis Intervention Trial (GAIT), compared glucosamine hydrochloride, chondroitin, both supplements together, celecoxib (a prescription drug used to manage osteoarthritis pain), or a placebo (an inactive substance) in patients with knee osteoarthritis. (nih.gov)
  • However, the largest and best studies (including the NIH study discussed under the heading "Glucosamine" above) showed that chondroitin doesn't lessen osteoarthritis pain. (nih.gov)
  • For example, 57.4 percent of participants in this new study who reported osteoarthritis of the knee reported having low-back pain as well. (massagemag.com)
  • Use of complementary medicines for osteoarthritis - a prospective study. (sma.org)
  • This study aimed to observe and analyse interactions between General Practitioners (GPs) and patients presenting with osteoarthritis (OA), in order to identify how to improve care for OA. (whiterose.ac.uk)
  • It is curious that the average age at diagnosis in the present study was 70–72 years whereas in the United States the mean age at osteoarthritis diagnosis is 53 years. (cdc.gov)
NIAMS3
  • The goal of the Health Disparities in Osteoarthritis (OA) workshop, sponsored by NIAMS, NIA, and NIMHD, is to identify research gaps/needs that could be addressed in future NIH activities. (nih.gov)
  • Health disparities in osteoarthritis (day 1 & 2) / NIAMS, NIA and NIMHD. (nih.gov)
  • For more information about osteoarthritis, visit the National Institute of Arthritis and Musculoskeletal and Skin Diseases Web site at www.niams.nih.gov . (nih.gov)
Complementary2
  • For more information on complementary health approaches for osteoarthritis, see the National Center for Complementary and Integrative Health (NCCIH) fact sheet Osteoarthritis and Complementary Health Approaches . (nih.gov)
  • Use of complementary therapies among primary care clinic patients with arthritis [serial online]. (sma.org)
Common2
Diagnosis1
Progresses1
Inactivity1
  • Moreover, they have more varicose veins, which might be associated both to treatments, as well as to the inactivity caused by knee osteoarthritis. (bioiberica.com)
Painful1
  • Unlike many previous studies of what determines the decision (not) to consult for painful osteoarthritis, by using a conjoint analysis design we were able to quantify the relative importance of both service-related factors and patient/problem characteristics. (bmj.com)
Disparities1
  • Therefore, identifying the important biopsychosocial factors that might explain racial disparities attributed to HR-QOL among knee OA patients is an essential step to redress the observed health disparity. (cdc.gov)
Primary care5
  • Below is a catalog- by topic- of the many community and online resources for patients that are described throughout the Osteoarthritis Prevention and Management in Primary Care Toolkit. (unc.edu)
  • Beliefs about osteoarthritis and what primary care has to offer may influence the decision to consult but their relative importance has seldom been quantified. (bmj.com)
  • Alongside the recognition and management of disrupted function, an important goal of each primary care consultation for osteoarthritis should be to avoid imparting or reinforcing this perception. (bmj.com)
  • Development of a practice-based patient cohort for primary care research. (sma.org)
  • Purpose Patients and doctors report marked disenchantment with primary care consultation experiences relating to osteoarthritis. (whiterose.ac.uk)
Cohort1
Managing3
  • One of the most important aspects of managing patients with knee OA, according to Dr. Mooar, is to provide education about the objectives of treatments and the importance of lifestyle changes. (physiciansweekly.com)
  • This patient handout describes resources and programs available for adults with OA to support physical activity, weight loss, managing pain, self-care, social support, and medical care. (unc.edu)
  • Managing osteoarthritis: medication use among seniors in the community. (sma.org)
Placebo1
Occurs1