Patients with newly diagnosed. Medical search. Frequent questions

In daily practice and at whole country level, oncological care management for glioblastoma patients is not completely known. (springer.com)
To describe oncological patterns of care, prognostic factors, and survival for all patients in France with newly-diagnosed and histologically confirmed glioblastoma, and evaluate the impact of extended temozolomide use at the population level. (springer.com)
Nationwide population-based cohort study including all patients with newly-diagnosed and histologically confirmed glioblastoma in France in 2008 and followed until 2015. (springer.com)
Data from 2053 glioblastoma patients were analyzed (male/female ratio 1.5, median age 64 years). (springer.com)
In the ACT IV study, we aimed to assess whether or not the addition of rindopepimut to standard chemotherapy is able to improve survival in patients with EGFRvIII-positive glioblastoma. (nih.gov)
In this randomised, double-blind, phase 3 trial, we recruited patients aged 18 years and older with glioblastoma from 165 hospitals in 22 countries. (nih.gov)
Eligible patients had newly diagnosed glioblastoma confirmed to express EGFRvIII by central analysis, and had undergone maximal surgical resection and completion of standard chemoradiation without progression. (nih.gov)
Rindopepimut did not increase survival in patients with newly diagnosed glioblastoma. (nih.gov)
This survival data shows the potential of IN8bio's DeltEx Drug Resistant Immunotherapy (DRI) - genetically modified and chemotherapy-resistant gamma-delta T cells to treat patients with newly diagnosed glioblastoma (GBM). (cbs17.com)
The Company's lead program is a 348-patient Phase III trial in newly diagnosed Glioblastoma multiforme (GBM). (prnewswire.com)

Since 2005, one pivotal clinical trial defined the radiotherapy and temozolomide combination (RT-temozolomide) as the standard of care in patients with newly-diagnosed GBM, for patients 18-70 years old with a WHO performance status of ≤ 2 [ 6 ]. (springer.com)
This study analysed a broad range of possible ocular and non-ocular predictors of visual impairment prospectively in patients newly diagnosed with clinical type 2 diabetes. (biomedcentral.com)
Data were from a population-based cohort of 1,241 persons newly diagnosed with clinical, often symptomatic type 2 diabetes aged ≥ 40 years. (biomedcentral.com)
In the history of diabetes treatment, the development of diabetic retinopathy has been included in the outcome of numerous clinical trials though prevention of visual loss is the ultimate target for the patients. (biomedcentral.com)
NEW YORK, Nov. 20, 2023 (GLOBE NEWSWIRE) -- IN8bio, Inc. (Nasdaq: INAB), a leading clinical-stage biopharmaceutical company developing innovative gamma-delta (γδ) T cell therapies, presented data demonstrating that all patients treated with INB-200 who completed mandated doses have exceeded a progression-free survival (PFS) of seven months to date. (cbs17.com)
comparative data published in the New England Journal of Medicine (NEJM) in August 2023 demonstrate that IDH-mutant patients in the control arm of a clinical trial demonstrated a median PFS of 11.1 months. (cbs17.com)
The Inception Cohort Registry Study of Patients with Crohn's Disease aimed to clarify clinical characteristics and disease course of newly diagnosed Crohn's disease patients in Japan throughout a 4-year period. (bvsalud.org)
Results from the PULSAR randomized clinical trial that compared 2- and 8-mg doses of the drug showed that 89% of the patients who received the higher dose achieved at least every-3-month dosing and 78% achieved every-4-month dosing at the 96-month mark, Paolo Lanzetta, MD, of the University of Udine in Udine, Italy, reported at EURETINA 2023. (medscape.com)
The aim of this study was to investigate the SDM preference and the satisfaction with and need for information among newly diagnosed HM patients and their informal caregivers, in relation to sociodemographic and clinical factors, cognitive coping style, and health related quality of life. (amsterdamumc.org)
Among patients, total need for information was related to MCCS (P = .012), and need for specific information was related to MCCS and several clinical factors. (amsterdamumc.org)
Medical records were consulted to retrieve sociodemographic and clinical factors and comorbidity by means of the ACE-27.RESULTS: Questionnaires were completed by 138 patients and 95 caregivers. (amsterdamumc.org)
The most common reasons for not initiating ARV therapy were lack of clinical indication and departure of patients before their visit with the HIV Specialist. (confex.com)
Today's positive CHMP opinion for quizartinib is an important step towards translating the clinical benefit observed in QuANTUM-First into an approved treatment option for patients in the EU with the difficult-to-treat FLT3 -ITD subtype of acute myeloid leukemia," Mark Rutstein, MD, global head, Oncology Clinical Development, Daiichi Sankyo, stated in a news release. (onclive.com)
The group is composed of key stakeholders from federal and state programs, researchers, patient advocates, and clinical practitioners with expertise in public/population health, health disparities, health literacy, implementation science, medical genetics, and patient advocacy. (cdc.gov)
Yoichi Kakuta et al, Novel Diagnostic Autoantibodies Against Endothelial Protein C Receptor in Patients With Ulcerative Colitis, Clinical Gastroenterology and Hepatology (2021). (medicalxpress.com)
Beyond the neonatal period, chorioretinitis can be diagnosed in diverse clinical conditions and can reflect newly acquired diseases or reactivation. (medscape.com)
Bergqvist J, Iderberg H, Mesterton J, Bengtsson N, Wettermark B, Henriksson R. Healthcare resource use, comorbidity, treatment and clinical outcomes for patients with primary intracranial tumors: a Swedish population-based register study. (janusinfo.se)
The purpose of this study was to examine employment trajectories in a cohort of early-stage breast cancer patients from treatment to 2-year follow-up, and evaluate relationships between sociodemographic, clinical/treatment, and psychosocial factors and employment outcomes. (cdc.gov)

In this cohort study, 139 consecutive patients with newly diagnosed and previously untreated inflammatory bowel disease - 95 with ulcerative colitis (UC) and 44 with Crohn's disease (CD) - underwent colonoscopy. (nih.gov)
This retrospective cohort study of mUTUC patients aged 66 or older from the SEER-Medicare database showed that less than half received care that met quality care criteria. (medpagetoday.com)
Forslund T, Wettermark B, Andersen M, Hjemdahl P. Stroke and bleeding with NOAC or warfarin treatment in patients with non-valvular atrial fibrillation: a population based cohort study. (janusinfo.se)
Evans M, Carrero JJ, Bellocco R, Barany P, Qureshi AR, Seeberger A, Jacobson SH, Hylander-Rössner B, Rotnitzky A, Sjölander A. Initiation of erythropoiesis-stimulating agents and outcomes: a nationwide observational cohort study in anaemic chronic kidney disease patients. (janusinfo.se)
Methods: Data from a cohort study of newly diagnosed early-stage breast cancer patients were used to examine employment outcomes among 347 working-age patients, 40-64 years old. (cdc.gov)

We are closely monitoring reports of people newly diagnosed with mpox after vaccination. (cdc.gov)

High-dose therapy (HDT) combined with autologous stem-cell transplantation (ASCT) provides superior response and survival outcomes versus standard chemotherapy in patients with newly diagnosed (ND) multiple myeloma (MM). 1 , 2 Standard induction chemotherapy regimens, however, are often associated with hematologic stem-cell toxicity, which may compromise the collection of stem cells for ASCT. (haematologica.org)
Introduction: Mold-active primary antifungal prophylaxis (PAP) is widely recommended in neutropenic patients (pts) with newly diagnosed acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) who undergo remission-induction chemotherapy (RIC). (confex.com)
From 2015 to 2017, the MAIA trial enrolled 737 patients with newly diagnosed multiple myeloma (median age = 73 years) ineligible for high-dose chemotherapy and stem cell transplant. (ascopost.com)
Patients with MTAP-deletion had a shorter time to progression to metastatic disease and inferior response to chemotherapy. (medpagetoday.com)
A study led by The University of Texas MD Anderson Cancer Center showed that treatment combining lower doses of chemotherapy with the monoclonal antibody inotuzumab ozogamicin (INO), with or without the drug blinatumomab, is safe and effective in patients over 60 years of age who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative ALL. (hoffie.net)
A total of 331 of 604 patients with high-grade glioma (54.8%) and 159 of 397 with low-grade glioma (40.1%) received postsurgical radiotherapy, and 285 patients with high-grade tumors (47.1%) and 80 with low-grade tumors (20.2%) received adjuvant chemotherapy. (jglioma.com)
Immunotherapy with monoclonal antibodies, such as blinatumomab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread It is not yet known whether combination chemotherapy is more effective with or without blinatumomab in treating newly diagnosed acute lymphoblastic leukemia. (clinicaltrialsgps.com)
I. To compare the overall survival (OS) of blinatumomab in conjunction with chemotherapy to chemotherapy alone in patients with BCR-ABL-negative B cell precursor acute lymphoblastic leukemia (ALL) who are minimal residual disease (MRD) positive after induction and intensification chemotherapy, based on multiparameter flow cytometric (MFC) assessment of residual blasts. (clinicaltrialsgps.com)
I. To compare the relapse-free survival (RFS) of blinatumomab in conjunction with chemotherapy to chemotherapy alone in MRD positive patients, MRD negative patients and overall population after induction and intensification chemotherapy. (clinicaltrialsgps.com)
To compare the OS and RFS of those patients who are MRD+ at step 3 randomization/ registration and then convert to MRD- after 2 cycles of blinatumomab to those patients who are MRD- at randomization and remain MRD- after 2 cycles of blinatumomab or consolidation chemotherapy. (clinicaltrialsgps.com)
To assess the toxicities of the modified E2993 chemotherapy regimen in this patient population. (clinicaltrialsgps.com)
The Committee for Medicinal Products for Human Use has recommended the approval of quizartinib in the European Union for use in combination with standard cytarabine and anthracycline induction and cytarabine consolidation chemotherapy, followed by maintenance quizartinib, for adult patients with newly diagnosed acute myeloid leukemia. (onclive.com)
Data from QuANTUM-First served as the basis for the July 20, 2023, FDA approval of quizartinib plus standard induction and consolidation, and as maintenance monotherapy following consolidation chemotherapy, in patients with newly diagnosed AML that is FLT3 -ITD positive, as detected by an FDA-approved test. (onclive.com)
Patients were randomly assigned 1:1 to receive quizartinib or placebo plus cytarabine and anthracycline induction and cytarabine consolidation chemotherapy followed by up to 3 years of treatment with quizartinib or placebo, respectively. (onclive.com)
The 55 patients were not eligible for the Phase III trial because they were either definitely or potentially "rapid progressors": patients with such an aggressive form of GBM that their tumor was already re-growing during the 6 weeks of daily radiation to the brain and daily chemotherapy which followed the surgical removal of their original tumor as part of the current standard of care. (prnewswire.com)

Furthermore, although most patients respond well to immunosuppressive therapy, progression and end-stage liver disease occur in 10%-20% of cases and liver transplantation may be necessary [ 4 ]. (hindawi.com)
Moreover, "standards of care" do not exist for progression/recurrent GBM patients (e.g., bevacizumab was approved for treatment of recurrent GBM in USA, but not in Europe). (springer.com)
These data provide a new progression-free survival benchmark in patients with newly diagnosed multiple myeloma who are transplant-ineligible," Dr. Facon said. (ascopost.com)
Patients continued treatment until disease progression. (ascopost.com)
Every patient in the Phase 1 trial that completed the mandated doses has exceeded the standard-of-care median progression-free survival of four to seven months, with one patient in Cohort 2 remaining alive and progression free past 28.5 months following three doses," said Trishna Goswami, MD, Chief Medical Officer at IN8bio. (cbs17.com)
Guidelines recommend adjuvant treatment for patients with high-grade gliomas and low-grade gliomas with high risk of progression. (jglioma.com)
The finding could lead to the development of non-invasive, diagnostic blood test to both identify the disease and to determine progression in patients, according to the researchers. (medicalxpress.com)
The data received by the Company include the survival to date for all 55 patients in the "Information Arm" and data relating to the progression of their cancer for 43 of the 55 patients. (prnewswire.com)
A systematic review by He et al demonstrated a reduction in vertebral compressions and time to progression with early systemic treatment for asymptomatic patients, but this study also revealed an increase in acute leukemia in the early treatment group. (medscape.com)
[ 34 ] A study by Neben et al concludes that long-term administration of bortezomib in patients with del(17p13) may result in better overall and progression-free survival. (medscape.com)

Patients newly diagnosed with Crohn's disease after June 2016 (age ≥ 16 years at informed consent ) were enrolled between December 17, 2018 and June 30, 2020. (bvsalud.org)
Melissa is a breast cancer survivor, diagnosed in 2020 at the age of 48. (breastfriends.org)

Design and Methods Oral cyclophosphamide, thalidomide, and dexamethasone was compared with infusional cyclophosphamide, vincristine, doxorubicin, and dexamethasone in patients with newly diagnosed multiple myeloma. (haematologica.org)
Methods: We reviewed the medical records of all consecutive pts with newly diagnosed AML/MDS or ALL treated at our institution from 3/2016-7/2019. (confex.com)
Methods FDG-PET was performed on a cohort of 79 patients with newly diagnosed PD (mean disease duration 8 months) and 20 unrelated controls. (bmj.com)
METHODS: One hundred seventy-three newly diagnosed Mexican breast cancer patients participated in the study. (rug.nl)
This study assessed levels and correlates of supportive care needs of Mexican breast cancer patients around the time of cancer diagnosis.METHODS: One hundred seventy-three newly diagnosed Mexican breast cancer patients participated in the study. (rug.nl)
METHODS: Newly diagnosed patients and their caregivers were asked to complete the Hematology Information Needs Questionnaire, the Information Satisfaction Questionnaire, and the Threatening Medical Situations Inventory. (amsterdamumc.org)

Medical records and radiologic images of 1215 glioma patients who underwent surgery at the center from 2000 to 2017 were retrospectively reviewed, and their clinicopathological characteristics, treatment method, and overall survival (OS) were analyzed. (jglioma.com)

Schmidt-Mende K, Andersen M, Wettermark B, Hasselström J. Educational intervention on medication reviews aiming to reduce acute healthcare consumption in elderly patients with potentially inappropriate medicines -A pragmatic open-label cluster randomized controlled trial in primary care. (janusinfo.se)

PURPOSE: Mexican breast cancer patients are generally diagnosed in advanced stages of the disease and often experience delays in cancer treatment delivery. (rug.nl)
This study assessed levels and correlates of supportive care needs of Mexican breast cancer patients around the time of cancer diagnosis. (rug.nl)
CONCLUSIONS: This study suggests that mainly health system/information needs arise at the time of cancer diagnosis among Mexican breast cancer patients. (rug.nl)
Future studies should be conducted to elucidate the care needs throughout the disease trajectory, as such information can inform health care professionals and policy makers and lead to improvements in the organization and provision of health care services for Mexican breast cancer patients. (rug.nl)
Patients with higher levels of depressive symptoms had higher psychological (β = 0.38), physical/daily living (β = 0.43), patient care/support (β = 0.17), and additional unmet care needs (β = 0.30), than patients with lower levels of depressive symptoms.CONCLUSIONS: This study suggests that mainly health system/information needs arise at the time of cancer diagnosis among Mexican breast cancer patients. (rug.nl)
A FREE public event benefitting newly diagnosed Breast Cancer patients! (cityofsanmateo.org)
Brooks was diagnosed with breast cancer in the summer of 2021. (breastfriends.org)
After being diagnosed with Breast Cancer in January 2022, Katje called Breast Friends and immediately felt at home amongst other women in the support groups and activities she went to. (breastfriends.org)
At 37 years old, Alyssa was diagnosed with Triple Negative breast cancer and feels grateful every day to be thriving after treatment. (breastfriends.org)

New research from Aarhus University now shows that younger persons newly- diagnosed with type 2 diabetes have significantly poorer health and thus a high risk of delayed complications compared with type 2 diabetes patients who first contract the disease twenty years later in life. (news-medical.net)
Seeing early signs of diabetes complications among young patients is very serious, says Anne Bo, master of science in public health science from Aarhus University. (news-medical.net)
When patients are already affected by type 2 diabetes at such a young age, the damage can develop into blindness, kidney failure or life-threatening cardiovascular diseases, as they must live with the disease for decades. (news-medical.net)
This points towards a need to rethink the way the healthcare sector organizes type 2 diabetes treatment, and not least, how the younger type 2 diabetes patients are met by healthcare professionals,' says Anne Bo. (news-medical.net)
Many patients feel a lot of guilt and shame about getting type 2 diabetes, which is related to lifestyle. (news-medical.net)
However, the question of why the group of younger diabetic patients is growing is complex, says Helle Terkildsen Maindal, professor of health promotion at Aarhus University, research manager at the Steno Diabetes Center Copenhagen and last author of the research study. (news-medical.net)
Many diabetic patients fear visual loss as the worst consequence of diabetes. (biomedcentral.com)
Our main aim was to study a broad range of predictors of vision loss in a population-based sample of patients newly diagnosed with type 2 diabetes and observed for 6 years. (biomedcentral.com)
In the Danish Diabetes Care in General Practice study [ 24 ], 474 general practitioners agreed to include all subjects with newly diagnosed diabetes on their practice list (Figure 1 ). (biomedcentral.com)
Although the mechanism of low urinary pH in many patients may not be completely clear and can be multifactorial, studies suggest an association between diabetes and insulin resistance in patients with normal urinary uric acid levels and acidic urine. (medscape.com)
Acidic urine and uric acid stones have been reported as more common in patients with non-insulin-dependent diabetes than in patients with stones who do not have diabetes. (medscape.com)
Variants of GCKR affect both beta cell and kidney function in patients with newly diagnosed type 2 diabetes. (univr.it)
We tested whether GCKR variability affects type 2 diabetes or kidney-related phenotypes in newly diagnosed type 2diabetes. (univr.it)
Genotyping GCKR in patients withnewly diagnosed type 2 diabetes might help in identifying patients at high risk for metabolic derangements or CKD. (univr.it)
List the steps that comprise a foot assessment in patients with diabetes. (wildirismedicaleducation.com)
Patients who develop a DFU are at higher risk of early death, heart attack, and fatal stroke than people with diabetes who do not develop diabetic foot ulcers. (wildirismedicaleducation.com)
One promising approach to treating type 1 diabetes is implanting pancreatic islet cells that can produce insulin when needed, which can free patients from giving themselves frequent insulin injections. (medicalxpress.com)
Treating newly diagnosed type 1 diabetes patients with semaglutide (trade names Ozempic, Wegovy and Rybelsus) may drastically reduce or even eliminate their need for injected insulin. (medicalxpress.com)

A total of 1001 patients diagnosed with glioma (initially World Health Organization 2007 criteria, then 2016 criteria) were enrolled, including 90 patients with Grade I, 307 Grade II, 239 Grade III, and 365 Grade IV gliomas. (jglioma.com)
The median OS of patients with low-grade glioma was not reached. (jglioma.com)
Glioma patients are not always treated according to guidelines. (jglioma.com)

The study treated 64 patients with a median age of 68 years. (hoffie.net)

What extent of combined RT-temozolomide treatment did patients receive (concomitant phase only, initiation of adjuvant phase, 6 cycles of temozolomide in maintenance or more)? (springer.com)
Unlike already diagnosed patients, who generally require continuation of prior care, newly diagnosed patients require many services including assessment for possible anti-retroviral initiation. (confex.com)
Recent changes to guidelines for ARV initiation have not significantly increased the percentage of newly identified patients who are initiated on ARV's because significant challenges exist for ARV initiation in jail, including short stay, HIV stigmatization and concerns about adherence. (confex.com)
1.Analyze the decision making surrounding initiation of ARV s among newly diagnosed HIV+ patients in the NYC jail system. (confex.com)
Time in Therapeutic Range and Outcomes After Warfarin Initiation in Newly Diagnosed Atrial Fibrillation Patients With Renal Dysfunction. (janusinfo.se)

All HIV-infected patients undergoing treatment for TB should be evaluated for antiretroviral therapy, because most patients with HIV-related TB are candidates for concurrent administration of antituberculosis and antiretroviral drug therapies. (cdc.gov)
Physicians and patients also should be aware that paradoxical reactions might occur during the course of TB treatment when antiretroviral therapy restores immune function. (cdc.gov)
Progress has been made in testing tuberculosis patients for HIV infection, but provision of co-trimoxazole prophylaxis and antiretroviral therapy, the two crucial interventions for HIV-positive tuberculosis patients, is about one third of that targeted in the Global Plan. (who.int)

[ 2 ] Therefore, a subset of patients with idiopathic uric acid stones may have a broader systemic disorder of insulin resistance. (medscape.com)
Two reference groups included 59 non-welder trade workers and 118 newly diagnosed, untreated idiopathic PD patients. (cdc.gov)
UPDRS3 scores for most domains were similar between welders and newly diagnosed idiopathic Parkinson disease (PD) patients, except for greater frequency of rest tremor and asymmetry in PD patients. (cdc.gov)

The 60- and 96-week results that Lanzetta shared at EURETINA 2023 showed that 91.5% of all patients in PULSAR completed the 60-week readout, with an average discontinuation rate of 7.9% before 60 weeks. (medscape.com)
She joined Breast Friends in 2023 as a Patient Outreach Specialist, focusing on outreach and programming for the Latinx community. (breastfriends.org)

In this interview, Duke researcher John Dudinec discusses his recent study assessing long-term outcomes of patients who received radical nephroureterectomy or nephron-sparing surgery. (medpagetoday.com)

A trend toward an overall survival advantage for cyclophosphamide-thalidomide-dexamethasone over cyclophosphamide-vincristine-doxorubicin-dexamethasone was also observed in a subgroup of patients with favorable interphase fluorescence in situ hybridization. (haematologica.org)
Combination vincristine, doxorubicin, and dexamethasone (VAD) is considered a standard infusional induction therapy for younger MM patients prior to HDT and ASCT. (haematologica.org)
In an updated analysis of the phase III MAIA trial, the addition of daratumumab to lenalidomide and dexamethasone resulted in a statistically significant overall survival benefit over lenalidomide/dexamethasone alone in patients with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplant. (ascopost.com)
These results strongly support upfront daratumumab with lenalidomide and dexamethasone (D-Rd) as a new standard of care for patients with transplant-ineligible newly diagnosed multiple myeloma," Dr. Facon said. (ascopost.com)
In both arms, patients received lenalidomide at 25 mg on days 1 to 21 of each cycle and dexamethasone at 40 mg weekly. (ascopost.com)

Two evidence-based genomic applications were used as examples of "interventions", including 1) universal tumor testing for Lynch syndrome (LS) in all individuals with newly diagnosed colorectal cancer, and 2) screening to identify family history associated with hereditary breast and ovarian cancer (HBOC) syndrome, accepting that the outcome measures may be applied to other genetic conditions. (cdc.gov)
Anti-EPCR antibodies were found to be specifically expressed in patients with inflammatory bowel disease when compared with healthy subjects and other colorectal diseases, with a particularly high sensitivity for patients with ulcerative colitis," Kakuta said. (medicalxpress.com)

Plasma TWEAK levels do not reflect disease activity or the grade of inflammation in patients with newly diagnosed inflammatory bowel disease. (nih.gov)
Serum samples of patients with inflammatory bowel disease stored at Tohoku University Hospital. (medicalxpress.com)
We found that patients with inflammatory bowel disease, especially ulcerative colitis, have high levels of antibodies programmed to target endothelial protein C receptors," said first author Yoichi Kakuta, associate professor, Division of Gastroenterology at Tohoku University Hospital. (medicalxpress.com)
To further explore the potential connection between the antibodies and ulcerative colitis, they analyzed the blood samples of 303 patients, 203 with inflammatory bowel disease and 100 without, in Japan and in the United States. (medicalxpress.com)

Objective: To avoid over-treatment of low-risk prostate cancer patients, it is important to identify clinically significant and insignificant cancer for treatment decision-making. (lu.se)
The multivariate analysis showed that the risk of mortality was significantly higher for the non-progressive patients who stopped at 6 cycles (standard protocol) than those who continued the treatment, hazard ratio = 1.5 (95% CI 1.2-1.9). (springer.com)
Patients, investigators, and the trial funder were masked to treatment allocation. (nih.gov)
16 deaths in the study were caused by adverse events (nine [4%] in the rindopepimut group and seven [3%] in the control group), of which one-a pulmonary embolism in a 64-year-old male patient after 11 months of treatment-was assessed as potentially related to rindopepimut. (nih.gov)
At the time of the analysis, 42% of patients in the D-Rd arm remained on treatment, compared to 18% of the Rd arm. (ascopost.com)
Our results underline the importance of eliminating barriers to efficient eye care by increasing patients' and primary care practitioners' awareness of the necessity of regular eye examinations and timely surgical treatment. (biomedcentral.com)
In the ICON-7 trial dataset, the OS of patients within the low- and high-risk disease groups was assessed according to treatment arms and KELIM. (ucl.ac.uk)
We are excited by the safety and efficacy results across cohorts in this study and look forward to dosing additional patients with the added hope of improving their treatment outcomes. (cbs17.com)
Rates of adverse events related to treatment were comparable across the 2q8, 8q12, and 8q16 arms through 96 weeks, with 45.2%, 42.4%, and 42.3% of patients reporting at least one such event, he said. (medscape.com)
At week 96, almost 30% of patients on either 8q12 or 8q16 achieved a last-assigned treatment interval of q24, he said. (medscape.com)
In patients with hyperuricosuria, dietary purine restriction is the initial treatment. (medscape.com)
Multivariate analysis identified onset age, preoperative seizure, tumor location, pathological subtype, resection extent, and postsurgical treatment as independent predictors of OS in patients with high-grade gliomas. (jglioma.com)
V. To describe the outcome of patients who proceed to allogeneic blood or marrow transplant after treatment with or without blinatumomab. (clinicaltrialsgps.com)
Patients are then randomized to 1 of 2 treatment arms. (clinicaltrialsgps.com)
Radical open surgical excision is the treatment of choice for patients with localized malignancies and remains the only method by which long-term disease-free survival may be achieved. (cancer.gov)
Because alternatives to the use of rifampin for antituberculosis treatment are now available, the previously recommended practice of stopping protease inhibitor therapy to allow the use of rifampin for TB treatment is no longer recommended for patients with HIV-related TB. (cdc.gov)
ABSTRACT We assessed the effect of community participation on treatment outcomes for tuberculosis patients undergoing directly-observed therapy, short course (DOTS). (who.int)
172 newly diagnosed patients in Baghdad were allocated into 2 treatment groups. (who.int)
Rooms, resources and support for patients in active cancer treatment who live more than 40 miles from their treatment center. (healthpartners.com)
85% of sputum smear-positive patients with pulmonary tuberculosis under treatment. (who.int)
The internationally agreed target for 2005 of a treatment success rate of at least 85% under the DOTS strategy was reached globally in 2007, but the case detection rate in 2008 of 62% of patients with sputum smear-positive pulmonary tuberculosis lagged behind the 71% target contained in the Global Plan. (who.int)
These 55 patients received the same DCVax-L treatment regimen used in the trial, at medical centers participating in the trial. (prnewswire.com)
In light of the extremely poor prognosis and short survival time of "rapid progressor" patients with standard of care today, the median Overall Survival observed in these patients who received treatment with DCVax-L in the "Information Arm" is unexpected and encouraging. (prnewswire.com)
Loikas D, Forslund T, Wettermark B, Schenck-Gustafsson K, Hjemdahl P, von Euler M. Increased thromboprophylactic treatment in patients with atrial fibrillation after the introduction of NOACs - an analysis of sex and gender differences. (janusinfo.se)
We examined patients' employment trajectories after definitive surgical treatment, using a multivariable logistic regression model to identify factors associated with diminished (versus sustained) employment at 2-year follow-up. (cdc.gov)
Results: A total of 245 patients (71%) were employed at least part-time at the time of definitive surgical treatment. (cdc.gov)
Conclusions: Patients with elevated fatigue and African Americans patients were more likely to experience diminished employment participation after definitive surgical treatment. (cdc.gov)
Overall, the care of patients with MM is complex and should focus on treatment of the disease process and any associated complications. (medscape.com)
Several studies are evaluating the role of treatment in patients with high-risk smoldering multiple myeloma (SMM). (medscape.com)
In a phase III trial that was restricted to patients with high-risk SMM, the PETHEMA group found evidence of benefit from treatment with lenalidomide versus observation. (medscape.com)

This work is requested by the French government and describes the oncological patterns of care, prognostic factors, and survival for all patients with newly-diagnosed and histologically confirmed GBM, for a country with more than 60 million inhabitants. (springer.com)
The study authors concluded, "After almost 5 years of follow-up, a significant and clinically meaningful overall survival improvement was demonstrated with the use of D-Rd vs Rd in patients with newly diagnosed multiple myeloma who are transplant-ineligible, representing a 32% reduction in the risk of death. (ascopost.com)
However, only the subgroup of patients with high-risk diseases (stage IV, and incompletely resected stage III) derived an overall survival (OS) gain in the ICON-7 trial (4.8 months). (ucl.ac.uk)
The current standard-of-care regimen for newly diagnosed GBM consists of primary resection, six weeks of chemoradiation therapy followed by six cycles of maintenance monthly temozolomide therapy, which achieves a median PFS of 7 months and an overall survival (OS) of approximately 14 to 16 months. (cbs17.com)
These investigators analyzed clinicopathological and outcomes data to better categorize the effects of 9 different types of variant histologies on disease-specific survival in patients with urothelial carcinoma of the bladder. (medpagetoday.com)
Ninety-five percent of all patients who responded showed no detectable minimal residual disease, which is an important endpoint in ALL therapy that has been shown to correlate with reduced risk of relapse and better long-term survival. (hoffie.net)
Older patients with Philadelphia chromosome-negative leukemia have historically had very poor outcomes, with long-term survival less than 20% in several prior studies," said Short. (hoffie.net)
With a median follow up of 37 months, the three-year overall survival rate was 54%, with 30 patients in complete remission with no signs of minimal residual disease. (hoffie.net)
In addition to the primary end point of OS, secondary end points include event-free survival, postinduction rates of complete remission (CR) and composite complete remission (CRc), and the percentage of patients who achieve CR or CRc with FLT3 -ITD measurable residual disease negativity. (onclive.com)
Although several studies have shown partial or even complete remission, there is no convincing evidence that systemic therapy will improve the survival duration of patients with adrenal cancer. (cancer.gov)
The update from the Company reported that the trial is progressing on track, and that 55 patients who were not eligible to enroll in the trial due to unusually rapid tumor recurrence were included in a compassionate use "Information Arm" and are showing encouraging survival times. (prnewswire.com)
the median Overall Survival for the 43 patients is a little over 19 months. (prnewswire.com)
this should lead to better overall survival in both transplant and non-transplant patients. (medscape.com)
[ 32 ] The failure to demonstrate improved survival may be due to the small number of patients studied. (medscape.com)

Following up on our oral presentation at this year's ASCO Annual Meeting, these encouraging results demonstrate the early promise of IN8bio's DeltEx DRI gamma-delta T cells for treating GBM patients and potentially other solid tumor cancers. (cbs17.com)

Around 2001, he was diagnosed with chronic lymphocytic leukemia (CLL), and he has stated that he was first veteran to be granted benefits by United States Department of Veterans Affairs acknowledging his cancer was a result of Agent Orange exposure during his time in Vietnam. (wikipedia.org)
Diabetic foot ulcers are complex, chronic wounds that are often disabling and greatly impact the morbidity and mortality of patients. (wildirismedicaleducation.com)
Up to two-thirds of patients with IBD have anemia as a result of disease-related iron malabsorption, chronic intestinal blood loss, and inflammation that impairs iron homeostasis. (medpagetoday.com)
1. Nephrology Department, diagnosed end-stage chronic renal failure patients. (who.int)
: [email protected] is a wrong perception of chronic kidney failure by patients in the end stage of their kidney disease due to the general public's low level of knowledge about kidney diseases. (who.int)

Only 22% patients received 6 cycles or more of adjuvant temozolomide (MS = 25.5, 95% CI 24.0-28.3). (springer.com)
In non-progressive patients, prolonging the adjuvant temozolomide beyond 6 cycles may improve OS. (springer.com)
Between April 12, 2012, and Dec 15, 2014, 745 patients were enrolled (405 with MRD, 338 with significant residual disease [SRD], and two unevaluable) and randomly assigned to rindopepimut and temozolomide (n=371) or control and temozolomide (n=374). (nih.gov)

The 140 patients without a measurement of visual acuity at diagnosis did not differ from the 1,241 patients who were included in the present study regarding age ( p = 0.36), sex ( p = 0.31) and diagnostic plasma glucose ( p = 0.81). (biomedcentral.com)
Patient demographics, diagnostic procedures and categories, disease location and lesion behavior (Montreal classification ) at the time of diagnosis were recorded. (bvsalud.org)
A longitudinal study of more than 65,000 bladder cancer patients reported a higher incidence of depression/anxiety within 6 months of diagnosis and that persisted for at least 3 years. (medpagetoday.com)
We will find out what life is like for patients just after their diagnosis and over the next year. (sheffield.ac.uk)
About 35 % of these patients had Mental Health diagnosis which is similar to the overall population in the NYC jail system. (confex.com)
The quick diagnosis means the patient could be referred to a specialist as soon as possible. (medicalxpress.com)

This study was conducted from February vision of DOTS therapy by an NGO was to December 2001 in Saddam city in Bagh- studied in a cohort of 205 smear-positive dad, which has a population of about 2 mil- patients [ 4 ]. (who.int)

On September 30, 2014, the Centers for Disease Control and Prevention (CDC) announced that Thomas Eric Duncan , a 45-year-old Liberian national visiting the United States from Liberia , had been diagnosed with Ebola in Dallas, Texas . (wikipedia.org)

When a patient with symptoms such as diarrhea or bloody stools visits a general clinic, it could be easy to diagnose ulcerative colitis by checking the antibody concentration in the blood," Kakuta said. (medicalxpress.com)
We would love to be in a situation like we are with influenza, where patients are diagnosed in a clinic or urgent care and then given a prescription for a pill that they can take at home that will prevent them from getting any sicker," said Dr. Aneesh Mehta , an infectious diseases specialist at Emory University Hospital. (latimes.com)

Furthermore, the younger newly-diagnosed patients are met by a healthcare sector that is not prepared for the patient group. (news-medical.net)
In the case of twenty percent of the younger patients, researchers discovered early signs of damage to the kidneys, while seven percent showed signs of eye problems. (news-medical.net)
The study shows that the group of younger newly-diagnosed patients have a much poorer health situation compared to the older diabetic patients. (news-medical.net)
The younger patients are more overweight, have poorer controlled blood sugar levels, higher cholesterol levels and almost the same presence of hypertension. (news-medical.net)
This can also contribute to the explanation of the younger patients' proportionately poorer health,' says Anne Bo. (news-medical.net)
When my younger cousins were diagnosed three years ago, the majority of the family and I were really unsure about what this meant for them. (foodallergybuzz.com)

In early 2019, she was hired as the Patient Programs Assistant. (breastfriends.org)

She refers to the patients' own experiences which were recorded in connection with the study. (news-medical.net)
The benefits are all the more meaningful because the study population was elderly-99% were age 65 or older, and 44% were aged 75 to 90, said Dr. Facon, who emphasized that half or more of nontransplant elderly patients never receive subsequent therapy. (ascopost.com)
Characteristics of adult patients newly diagnosed with Crohn's disease: interim analysis of the nation-wide inception cohort registry study of patients with Crohn's disease in Japan (iCREST-CD). (bvsalud.org)
Results from an interim analysis of the largest nation-wide registry study that covers approximately 1% of Crohn's disease patient population in Japan are reported. (bvsalud.org)
In this study, we reviewed the treatments and outcomes in patients with gliomas at Sun Yat-Sen University Cancer Center (SYSUCC), China. (jglioma.com)
The Verona Newly diagnosed type diabets study (VNDS). (univr.it)
QuANTUM-First is a randomized, double-blind, placebo-controlled, global phase 3 study evaluating quizartinib plus standard induction and consolidation therapy, including hematopoietic stem cell transplant (HSCT), and as maintenance monotherapy, in 539 adult patients aged 18 to 75 with newly diagnosed FLT3 -ITD positive AML. (onclive.com)
The design was a community intervention county in Switzerland showed that the suc- study with patients allocated to control or cess rate (cure or adequately completed intervention groups. (who.int)
Patients with anemia of new onset had an increased risk of developing Crohn's disease (CD), but not ulcerative colitis, and men were more at risk, according to a population-based study by South Korean researchers. (medpagetoday.com)

For example, numerous studies have revealed a transient and moderate increase in the production of Th1 cytokines, including interleukin-2 (IL-2), interferon- γ (IFN- γ ), and tumor necrosis factor α (TNF- α ) in AIH patients [ 6 , 7 ]. (hindawi.com)
In daily practice, oncological care management for GBM patients is not completely standardized and depends on many factors [age, Karnofsky performance status (KPS), comorbidity, tumor (location, shape, and volume), etc. (springer.com)
The French Brain Tumor DataBase (FBTDB) identified and recorded all patients with newly-diagnosed and histologically confirmed primary brain tumors (e.g. (springer.com)
Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. (cancer.gov)
All patients who completed mandated doses surpassed a PFS of seven months, with most also exceeding the expected PFS based on their age and tumor status. (cbs17.com)

The researchers previously identified the same anti-EPCR antibodies in patients with Takayasu arteritis, a disorder that causes blood vessels to inflame and can be complicated by ulcerative colitis. (medicalxpress.com)

An international research collaboration has discovered a potential new diagnostic marker for ulcerative colitis in a trans-ethnic analysis of Japanese and white patients. (medicalxpress.com)
The researchers also found that more than 93 percent of the patients with ulcerative colitis, arthritis and immune-related skin conditions were positive for the antibody. (medicalxpress.com)

RESULTS: Questionnaires were completed by 138 patients and 95 caregivers. (amsterdamumc.org)
Importantly, dissatisfaction with the information they received was reported by a third of the patients and caregivers, especially patients who wanted SDM (χ(2) = 7.3, P = .007), and patients with a higher MCCS (OR = 0.94, P = .038). (amsterdamumc.org)
Below is a list of support groups for people with cancer - including patients, loved ones and caregivers - as well as educational resources. (healthpartners.com)
A virtual support service that matches patients and caregivers with mentors of similar age and cancer experience. (healthpartners.com)
Free community-focused programs and groups for anyone affected by cancer - including patients, families, caregivers and friends. (healthpartners.com)
This includes a phone line for information and resource referrals, one-on-one mentoring for patients and caregivers, and an online support community. (healthpartners.com)

After 6 years, 807 patients were followed up. (biomedcentral.com)
The incidence (95% confidence interval) of blindness was 40.2 (25.3-63.8) per 10,000 patient-years. (biomedcentral.com)
This was a single questionnaire for people diagnosed with bladder cancer in the last 10 years. (sheffield.ac.uk)
During the mean follow-up period of 7.3 years, the incidences of CD and UC in anemic patients were 2.89 and 6.88 per 100,000 person-years, respectively, which translated to a significantly higher risk of CD in anemic patients than in non-anemic patients, for an adjusted hazard ratio (aHR) of 2.084 (95% CI 1.769-2.455). (medpagetoday.com)

Three major resistance mutations: K103N, M184V and Y188L, each of which caused more than one drug resistance were appeared only in two patients, the prevalence [1.7 % (2/119)] was relatively low. (neb.com)

Based on its oral administration and the reduced incidence of infection and cytopenia, cyclophosphamide-thalidomide-dexa-methasone may be considered an effective induction therapy option for patients with newly diagnosed multiple myeloma. (haematologica.org)
6 , 9 The demonstrated efficacy, lack of myelosuppression, and overall tolerability of thalidomide provide a strong rationale for its incorporation in standard induction regimens for patients presenting with NDMM who may be eligible for ASCT. (haematologica.org)
Ten (4.3%) pts had a bIFI (6 proven, 1 probable, 3 possible) during induction therapy while receiving PAP (Table 2) including 9 (4.8%) pts with AML/MDS and 1 (2.3%) patient with ALL. (confex.com)
INTENSIFICATION THERAPY: Beginning 4 weeks after the completion of course 2 of induction therapy, patients receive intensification therapy comprising high-dose methotrexate IV over 2 hours on days 1 and 8, and pegaspargase IM or IV on day 9. (clinicaltrialsgps.com)

Other mold-active agents including voriconazole (VCZ) and isavuconazole (ISA) or the echinocandins are alternatives which may be preferred in individual settings due to variations in toxicity, patient co-morbidities, drug interactions, and cost. (confex.com)

because more than half of these patients have sputum smears positive for acid-fast bacilli, they are potentially capable of transmitting the infection to other persons (CDC, unpublished data). (cdc.gov)
Adding to CDC's current recommendations for administering isoniazid preventive therapy to HIV-infected persons with positive tuberculin skin tests and to HIV-infected persons who were exposed to patients with infectious TB, this report also describes in detail the use of new short-course (i.e., 2 months) multidrug regimens (e.g., a rifamycin, such as rifampin or rifabutin, combined with pyrazinamide) to prevent TB in persons with HIV infection. (cdc.gov)

2021 presented an opportunity to change focus a bit and work as Patient Support Coordinator, giving Alyssa the opportunity to work more directly with women we serve. (breastfriends.org)

Default rates were similar in both groups (11.6% versus 10.5%), as was mortality (1 patient each). (who.int)
In contrast, no statistically significant difference in the risk of developing UC in anemic versus non-anemic patients emerged (aHR 0.972, 95% CI 0.880-1.073). (medpagetoday.com)

That way, the disease could be tamped down before the immune system has a chance to go haywire and cause the kinds of problems that send patients to the hospital. (latimes.com)
Poor help reduce transmission of the disease by patient compliance is a major factor con- killing the TB bacilli at source as early as tributing to the development of resistant in- possible. (who.int)
Rapid progressors" are usually excluded or segregated in studies and analyses because their disease is so accelerated that it is not comparable to regular GBM patients. (prnewswire.com)
Brazzaville University Hospital, considered a fairly worrying disease by 61.7% of patients. (who.int)

It is prudent to recognize the association and avoid further Bortezomib therapy in these patients. (jocrm.org)
Patients may then undergo allogeneic stem cell transplant (SCT) or proceed to consolidation therapy per investigator discretion. (clinicaltrialsgps.com)

2 ] However, more ACCs are being diagnosed at early stages, most likely because of the widespread use of high-quality imaging techniques. (cancer.gov)

Regular GBM patients survive for a median of about 14.6 months with current standard of care. (prnewswire.com)

CONCLUSION: The majority of HM patients want to be involved in SDM, but the received information is not sufficient. (amsterdamumc.org)

Patients who have low-grade tumors without evidence of invasion into local tissues or spread to lymph nodes have an improved prognosis. (cancer.gov)

All the newly identified HIV+ patients are immediately evaluated by a physician or physician assistant, HIV health educator within 48 hours and by an HIV Specialist (physician) within 2 weeks. (confex.com)

In addition, they have stated that they exercise less and smoke more than the elderly patients. (news-medical.net)

i) the proportion of persons with newly diagnosed CRC who receive genetic testing to identify LS, (ii) the proportion of women with a family history of HBOC/LS who receive genetic counseling, and (iii) the use of cascade screening for HBOC/LS. (cdc.gov)

Summarize the management program for patients with diabetic foot ulcers. (wildirismedicaleducation.com)

Glioblastoma10

Clinical18

Cohort study5

People newly diagnosed1

Chemotherapy15

Progression10

20202

Methods6

20171

Acute1

Breast cancer9

Diabetes18

Glioma3

Median age1

Initiation5

Antiretroviral3

Idiopathic3

20232

Outcomes of patients1

Dexamethasone5

Colorectal2

Inflammatory bowel d4

Treatment30

Survival14

Cancers1

Chronic5

Temozolomide3

Diagnosis6

20011

Centers1

Clinic2

Younger6

20191

Study9

Tumor5

Previously1

Ulcerative colitis2

Caregivers6

Years4

Prevalence1

Induction4

Toxicity1

Infection2

20211

Versus2

Disease4

Therapy2

Stages1

Standard of c1

Conclusion1

Tumors1

Physician1

Elderly patients1

Persons1

Diabetic1