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  • therapeutic
  • These data widen the allosteric and pharmacological landscape of NMDARs and offer a renewed structural framework for designing next-generation GluN2B antagonists with therapeutic value for brain disorders. (aspetjournals.org)
  • The new study provides experimental evidence that the emotional response to stress can be generated or blocked in the periphery, offering the potential for new forms of treatment for stress disorders and may eventually inform therapeutic strategies to reengineer a patient's immune system to reduce stress vulnerability. (medicalxpress.com)
  • dose
  • Patients have to be monitored for "at least two hours" after receiving a dose and can't drive for the rest of the day. (usatoday.com)
  • After 8 weeks of treatment, mean HAM-D scores dropped by 10.9 points in the placebo-treated controls, 16.3 points in the low-dose PH10 group, and 17.8 points in the high-dose arm, said Dr. Liebowitz, also managing director and founder of the Medical Research Network . (mdedge.com)
  • Baseline scores on the patient self-rated Quality of Life Enjoyment and Satisfaction Questionnaire ( QLESQ ) averaged 40 but improved by a mean of 20.3 points in the high-dose PH10 group, 15.3 points in the low-dose group, and 10.1 points in controls. (mdedge.com)
  • Three patients on high-dose PH10 reported an increase in appetite, as did one patient in the low-dose arm and two patients on placebo. (mdedge.com)
  • ADHD
  • It is also taken by mouth for attention deficit-hyperactivity disorder (ADHD), multiple sclerosis, spinal cord injury, seizures, migraine headache, lead poisoning, to break down a chemical in the body called bilirubin, or to help with disorders related to the buildup of a chemical called porphyrin or its precursors. (webmd.com)
  • rapid
  • The LFMS RAPID trial is currently recruiting patients (www.clinicaltrials.gov) at six leading academic medical centers. (healthcanal.com)
  • Cirrhosis
  • But some research suggests that giving SAMe by IV after surgery does not reduce the risk of mild liver dysfunction in patients with cirrhosis who undergo liver resection. (webmd.com)