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  • bone marrow
  • Patients will be assessed with a complete blood count weekly for the first 8 weeks and will have monthly physical examinations and bone marrow examinations every 3 months. (clinicaltrials.gov)
  • cancer
  • Determine the effects of SAHA on induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-death receptors DR4 and DR5 and other pro-apoptotic mediators in patient-derived cancer cells (leukemia blast cells) and somatic cells (buccal mucosa cells, using pre-SAHA and on SAHA treatment samples). (clinicaltrials.gov)
  • V. Determine the effects of SAHA on the expression of P-glycoprotein/MDR1/ABCB1, and the breast cancer resistance protein (BCRP/ABCG2), using functional and mRNA/protein assays for these transporters (leukemia blast cells, using pre-SAHA and on SAHA treatment samples). (clinicaltrials.gov)
  • undergo
  • NONMYELOABLATIVE CONDITIONING REGIMEN: Patients receive fludarabine phosphate intravenously (IV) on days -4 to -2 and undergo TBI on day 0. (clinicaltrials.gov)
  • diseases
  • In addition to treating the common cold and flu, internists also treat chronic diseases like diabetes and heart disease. (vitals.com)
  • GAB2 has also been associated with many diseases including leukemia and Alzheimer's disease. (wikipedia.org)