BenzamidesPiperazinesPyrimidinesLeukemia, Myelogenous, Chronic, BCR-ABL PositiveGastrointestinal Stromal TumorsFusion Proteins, bcr-ablAntineoplastic AgentsProto-Oncogene Proteins c-kitProtein Kinase InhibitorsReceptor, Platelet-Derived Growth Factor alphaLeukemia, Myeloid, Chronic-PhaseReceptor, Platelet-Derived Growth Factor betaBlast CrisisDrug Resistance, NeoplasmGenes, ablHypereosinophilic SyndromeCytogenetic AnalysisProto-Oncogene Proteins c-ablProtein-Tyrosine KinasesHypopigmentationK562 CellsGastrointestinal NeoplasmsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativePhiladelphia ChromosomeTreatment OutcomeRemission InductionReceptors, Platelet-Derived Growth FactorDermatofibrosarcomaMastocytosis, SystemicDrug ApprovalEnzyme InhibitorsPregnatrienesCell Line, TumorFibromatosis, AggressiveThiazolesDose-Response Relationship, DrugProto-Oncogene Proteins c-sisDisease-Free SurvivalHarringtoninesLeukemia, Myeloid, Accelerated PhaseApoptosisLichenoid EruptionsCell ProliferationInterferon-alphaAdministration, OralmRNA Cleavage and Polyadenylation FactorsPhosphorylationNeoplasm, ResidualDrug SynergismMutationKetonesTime FactorsGene Expression Regulation, LeukemicCytogeneticsSurvival AnalysisAntineoplastic Combined Chemotherapy ProtocolsFuransPyrrolesDrug Administration ScheduleUnited States Food and Drug AdministrationPrognosisRifabutinTreatment FailureSalvage TherapyPrimary MyelofibrosisDisease ProgressionChromosomes, Human, Pair 9In Situ Hybridization, FluorescenceHydroxyureaNeoplastic Stem CellsSTAT5 Transcription FactorPlatelet-Derived Growth FactorReverse Transcriptase Polymerase Chain ReactionSurvival RateRecurrenceScleroderma, SystemicHistiocytoma, Malignant FibrousPrecursor Cell Lymphoblastic Leukemia-LymphomaStem Cell FactorInhibitory Concentration 50Signal TransductionMyeloid Progenitor CellsRNA, MessengerFollow-Up StudiesFibrosisIndolesNeoadjuvant TherapyGraves OphthalmopathyCell SurvivalBlood Cell CountOncogene Proteins, FusionImmunohistochemistryCombined Modality TherapyAntigens, CD34Cells, Cultured