• The use of prophylactic antiepileptic drugs (AEDs) in patients undergoing craniotomy for tumor resection is controversial. (cns.org)
  • Our neurosurgical team implemented a protocol for withholding AEDs in seizure naive patents at the time of craniotomy for tumor resection. (cns.org)
  • A chart review was performed in which we identified all patients undergoing craniotomy for tumor resection. (cns.org)
  • After an initial chart review, 629 (317 female) underwent craniotomy for tumor resection. (cns.org)
  • Incidence of surgical site infection (SSI) among patients receiving craniotomy for tumor resection with a prior ventriculoperitoneal shunt is often higher than in non-shunted cases. (cns.org)
  • The patient underwent suboccipital craniotomy for gross total resection of the lesion. (cap.org)
  • Type B tumors are more common in adolescents and adults and have a good prognosis with a high probability of overall survival at 10 years after diagnosis, nearing 100% for patients with gross total resection and adjuvant radiation. (cap.org)
  • In both cases, en bloc tumor resection was successfully performed via a simultaneous exoscopic transcranial approach using a 3D-HMD and an endoscopic endonasal approach, eliminating the need to watch a large monitor beside the patient. (thejns.org)
  • The patient underwent craniotomy and resection of the tumor. (upmc.edu)
  • Background: When a brain tumor is located in the cerebrum (suptatentorial) and treated surgically, there are two options, awake craniotomy(AC) and general anesthesia GA. AC means that the patient is awake during the resection of the brain tumor. (gu.se)
  • The method enables maximum resection and simultaneous control over above all language and cognitive functions that cannot be monitored when the patient is anesthetized. (gu.se)
  • Purpose: The purpose of this systematic literature review is to systematically search, review and compile previously published research to identify patients intraoperative experiences of being awake during surgical craniotomy at resection of a brain tumor. (gu.se)
  • If our results are positive, this study will show that protective lung ventilation during dura opening can be used effectively and safely in neurosurgical patients undergoing craniotomy for tumor resection. (researchsquare.com)
  • In selected cases, surgical resection with the patient awake ( awake craniotomy ) is an alternative. (neuros.net)
  • This is, however, only recommended for procedures which have such a high risk of neurological sequelae that only 3 options will be left: the risk to be accepted (craniotomy), a partial resection to be performed, or an awake craniotomy to be chosen to assess better the neurological status of the patient during the surgical intervention. (neuros.net)
  • These procedures can include endonasal pituitary and skull base tumor resection, and open craniotomy treatment of tumors such as meningioma, glioblastoma, or acoustic neuroma, ventricular shunts, and/or neurosurgical procedures for hydrocephalus, deep brain stimulation electrodes, subdural hematoma evacuation, or ventricular endoscopy. (xorantech.com)
  • Bakgrund: När en hjärntumör är belägen i storhjärnan (supratentoriellt) och behandlas kirurgiskt finns det två alternativ, vaken kraniotomi (awake craniotomy, AC) och generell anestesi GA. AC innebär att patienten är vaken under resektionen av hjärntumören. (gu.se)
  • The best way to achieve this is the awake craniotomy . (neuros.net)
  • We are reporting preliminary data on the value of AED prophylaxis in brain tumor patients in the hopes of identifying a strategy that may improve their perioperative management. (cns.org)
  • We evaluated the infection rates of cefazolin and vancomycin for craniotomy for tumor patients with and without shunts. (cns.org)
  • An IRB-approved multi-armed, retrospective analysis of data pertinent to craniotomy for tumor, shunt, and prophylactic antibiotics was employed to evaluate infection rate in 210 patients during a nine-year period. (cns.org)
  • 3. To elucidate the efficacy of prophylactic antibiotics for craniotomy for tumor in consideration of prior shunt. (cns.org)
  • Tumor tissue from a rare non-infantile 8-year-old female DIG patient was dissociated and digested using collagenase to establish live cultures. (frontiersin.org)
  • Herein we assess the impact of implementing a protocol of more rigorous patient education, recovery room assessment for non-ICU admission, earlier mobilization and post-discharge communication for patients undergoing brain tumor surgery. (plos.org)
  • All patients undergoing craniotomy or endoscopic endonasal removal of a brain, skull base or pituitary tumor were included during two non-overlapping periods: March 2019-January 2020 (pre-pandemic epoch) versus March 2020-January 2021 (pandemic epoch with streamlined care protocol implemented). (plos.org)
  • Debate: For many patients with a long history of intracranial tumor issues such as complex meningiomas or recurrent gliomas, both traditional surgery coupled with additional non-traditional therapies may be beneficial due to its nature as a combined approach. (disabilityworks.org)
  • Patients with recurrent GBM who enroll in this clinical trial will undergo a biopsy to confirm tumor recurrence followed by implantation of one CMC catheter and infusion of OS9266 for four hours while being monitored by MRI. (moffitt.org)
  • They next undergo a craniotomy to remove the recurrent brain tumor, which will be evaluated for the effects of the treatment, and implantation of two CMCs into tumor-infiltrated brain surrounding the tumor. (moffitt.org)
  • Objective: To investigate the effects of protective lung ventilation on regional cerebral oxygen saturation during dura opening, that is from Ta (after dura opening) to Tb (before dura closing), in patients undergoing intracranial tumor surgery. (researchsquare.com)
  • Fifty-four patients undergoing intracranial tumor surgery will be randomly allocated to the control group (C group) or the protective lung ventilation group (P group). (researchsquare.com)
  • Discussion: This study aims to determine whether protective lung ventilation during dura opening can improve regional cerebral oxygen saturation and the state of pulmonary ventilation in patients undergoing intracranial tumor surgery, and to investigate whether this strategy does not affect the degree of brain tissue swelling and the reoperation rate after operation. (researchsquare.com)
  • Surgery in patients with astrocytoma is performed based on the size of the tumor in the brain and the functional status of the patients. (uns.ac.id)
  • Craniotomy in patients with astrocytoma is performed based on the size of the tumor in the brain and the functional status of the patient. (uns.ac.id)
  • The patient underwent a second MRI after being transferred to another hospital for neurosurgical removal of the tumor. (medscape.com)
  • This work presents a case report of a 33 year old patient who developed symptoms of interhemispheric disconnection and executive function defi cits after surgery for removal of a tumor in the pituitary region, as well as the evaluation of the applicability of the neuropsychological rehabilitation program for the cognitive com- plaints presented. (bvsalud.org)
  • Este estudio tiene como objetivo presentar un caso clínico de un paciente de 33 años, que desarrollaron síntomas de desconexión interhemisférica después de la cirugía para la extirpación del tumor en la región pituitaria y alteraciones en la función ejecutiva y evaluar la aplicabilidad del programa de rehabilitación neuropsicológica para las quejas cognitivas. (bvsalud.org)
  • patients undergoing large craniotomies showed greater midline shift and a higher rate of anisocoria. (minervamedica.it)
  • The three groups did not differ for functional outcome and postoperative midline shift, but the length of surgery and the rate of >50% of ASDH evacuation were lower in the small craniotomy group. (minervamedica.it)
  • After a multidisciplinary consultation among the neurosurgeon, obstetrician and anesthesiologists it was decided that the patient was under the risk of cerebral herniation due to the large intracranial mass causing a midline shift at the dominant hemisphere. (ispub.com)
  • The patient was premedicated with ranitidine 50 mg I.V. Anesthesia was induced with propofol 2 mg kg -1 and remifentanil 1 µg kg -1 I.V. bolus dose. (ispub.com)
  • More rigorous patient education, recovery room assessment for non-ICU admission, earlier mobilization and post-discharge communication, layered upon a foundation of minimally invasive surgery, TIVA anesthesia and early post-operative imaging are possible contributors to these favorable trends. (plos.org)
  • Induction of anesthesia with DIPRIVAN is frequently associated with apnea in both adults and pediatric patients. (guidelinecentral.com)
  • January 2023 Podcast -Dr. Jacqueline Morano interviews Dr. Ian McCullough, MD and Alex Papangelou, MD, authors of "Opioid-Free Anesthesia for Craniotomy. (snacc.org)
  • Anesthesia Patient Safety Foundation. (ahrq.gov)
  • Almost all these patients are under general anesthesia which is basically inseparable from mechanical ventilation. (researchsquare.com)
  • The pulmonary complications play an important role in death and disability in patients with general anesthesia[1-3]. (researchsquare.com)
  • Craniotomy always needs a long time for general anesthesia and prolonged mechanical ventilation, which leads to a higher risk of postoperative atelectasis and pulmonary infection[4,5]. (researchsquare.com)
  • STUDY OBJECTIVE: This meta-analysis aimed to compare the risk of brain swelling during craniotomy between propofol-based and volatile-based anesthesia. (bvsalud.org)
  • It has also been shown that patients tolerate the perioperative period well, but it is not sufficiently known how the patient experiences the intraoperative phase. (gu.se)
  • Results: The included studies resulted in four areas that describes patients´ intraoperative experiences: fear, pain, discomfort and memories which are linked to the specific moments performed intraoperatively. (gu.se)
  • Positive memories were observed mainly when the patient himself could be involved in the intraoperative phase while negative memories were again linked to the steps performed initially in the intraoperative phase. (gu.se)
  • Patients were excluded from the study if, 1) there was evidence of neurological symptoms unrelated to brain abscess, 2) there was evidence showing the patient had not undergone a drainage procedure or intraoperative pus sampling, or 3) the patient was lost to follow-up during the study period. (biomedcentral.com)
  • The study includes patients undergoing complex cranial neurosurgical procedures which can greatly benefit from low dose intraoperative imaging-allowing surgeons to view anatomy during surgery and confirming surgical completeness. (xorantech.com)
  • 2. To determine if prior shunting has any impact on infection rates following subsequent craniotomy. (cns.org)
  • Finally, we also studied the agreement with results of electrocortical stimulation (ECS) mapping from subsequent craniotomy, obtained while the patient was awake, if available. (ajnr.org)
  • To determine the demographics, management, and the variables that affect the outcome in subjects with brain abscesses treated at a single centre over an 11-year period, we retrospectively analysed data in 60 patients with brain abscesses surgically treated with stereotactically guided aspiration or open craniotomy excision in Shanghai Changzheng Hospital between January 2001 and December 2011. (biomedcentral.com)
  • Two primary treatments are used to manage brain abscesses: stereotactically guided aspiration and open craniotomy excision. (biomedcentral.com)
  • Stereotactically guided aspiration is the therapy of choice over open craniotomy excision because it is less invasive, thus reducing the likelihood of neurological sequelae. (biomedcentral.com)
  • METHODS: We selected patients ≥70 years old admitted to 5 Italian tertiary referral neurosurgical for the treatment of a post-traumatic ASDH between January 1st 2016 and December 31st 2019. (minervamedica.it)
  • Listen to the methods they chose and why they feel limiting opioids is important for patients undergoing supratentorial craniotomies. (snacc.org)
  • METHODS: This cross-sectional study included 167 patients with AF. (bvsalud.org)
  • Methods: A nationwide multicenter retrospective analysis of 341 patients who underwent craniotomy and evacuation of supratentorial ICH between January 1, 2011, and December 31, 2015, was performed. (lu.se)
  • I think what's happening is that these patients [in either group] are not getting pronounced brain swelling," Hutchinson said. (medscape.com)
  • Prognostic factors and survival of patients with brain metastasis from breast cancer who underwent craniotomy. (thieme-connect.com)
  • Dexamethasone 0.1 mg kg -1 , mannitol infusion 0.5 mg kg -1 and furosemid 0.1 mg kg -1 IV were administered to the patient to decrease brain edema and ICP. (ispub.com)
  • In patients who underwent craniotomy while awake, speech areas located with ECS coincided with areas of the brain activated during a word-generation task. (ajnr.org)
  • Functional MR (fMR) imaging is used to map eloquent brain regions before craniotomy because it depicts these regions more reliably and accurately than do anatomic landmarks visualized on MR images (1, 2) . (ajnr.org)
  • The following fictional case study discusses possible interventions for restoring physical and cognitive function during an in-patient rehabilitation program of a 65-year old woman who presented with a traumatic brain injury (TBI) . (physio-pedia.com)
  • female patients and patients greater than 40 years of age were most likely to suffer a brain abscess. (biomedcentral.com)
  • Additional studies will continue to reveal patients trends that may improve treatment for brain abscess. (biomedcentral.com)
  • This report is based on our experience with 82 brain abscesses surgically managed in 60 patients over an 11-year period at one single hospital. (biomedcentral.com)
  • Sixty patients with a total of 82 brain abscesses verified by postoperative pathology were treated surgically between January 2001 and December 2011 at the department of Neurosurgery in Shanghai Changzheng Hospital. (biomedcentral.com)
  • I felt it was too risky to undergo a craniotomy (invasive brain surgery) or transcatheter arterial embolization (insertion of a small tube into the AVM through an incision)," he says. (elekta.com)
  • We can monitor sensory-motor functions with intra-operative evoked potentials , but to identify and evaluate brain areas related to speech and comprehension (Broca and Wernicke areas) the best option is performing the surgery with the patient awake. (neuros.net)
  • MAIN RESULTS: Our meta-analysis of 17 RCTs showed a significantly lower risk of brain swelling (risk ratio [RR]: 0.85, p = 0.03, I2 = 21%, n = 1976) in patients receiving propofol than in those using volatile agents, without significant differences in surgical time or blood loss between the two groups. (bvsalud.org)
  • Stratified by craniotomy indications, propofol reduced brain swelling in elective craniotomy, but not in emergency craniotomy (e.g., traumatic brain injury), when compared to volatile anesthetics. (bvsalud.org)
  • In emergency craniotomy for traumatic brain injury and subarachnoid hemorrhage, brain swelling showed no significant difference between propofol and volatile agents. (bvsalud.org)
  • The dura is opened, and the meningioma can be seen extending en plaque over the surface of the brain. (medscape.com)
  • The commonest sites for cysts are infecting the brain after bypassing the The patient underwent a crani- the liver (59%-75%), followed in fre- liver and lungs [8,9]. (who.int)
  • Objective: To investigate long-term survival, neurologic outcome, and quality of life in patients with spontaneous supratentorial intracerebral hemorrhage (ICH) treated with craniotomy and hematoma evacuation. (lu.se)
  • BACKGROUND: Elderly patients operated for an acute subdural hematoma (ASDH) frequently have a poor outcome, with a high frequency of death, vegetative status, or severe disability (Glasgow Outcome Score, GOS, 1-3). (minervamedica.it)
  • The present study aimed to compare the influence of the size of the craniotomy on the functional outcome in patients undergoing surgical treatment for ASDH. (minervamedica.it)
  • BACKGROUND: While obesity has become an increasingly prevalent health concern in the United States, little emphasis has been placed on utilizing patient reported outcome measures (PROM) to investigate its impact. (koreamed.org)
  • Outcome measures were then used to reassess the patient's progress at week 4 of in-patient rehabilitation, including: the Berg balance scale, Ranchos Los Amigos scale, Modified Ashworth Scale, gait speed and distance measurements. (physio-pedia.com)
  • For treatment planning and outcome optimisation, specific patient features such bone quality, functional needs, and psychological variables are taken into account. (alliedacademies.org)
  • The outcome of one patient was poor due to the abscess in the basal ganglia region. (biomedcentral.com)
  • Conclusions: Knowledge about survival, functional outcome, and life quality as well as their predictors in this specific patient group is previously primarily described in short-term follow-up. (lu.se)
  • The case study was conducted by analyzing intervention data and the clinical outcome of the patient in the institutional records (results of neuropsychological evaluation examination and records of interventions in rehabilitation sessions). (bvsalud.org)
  • In a new study, outcomes were nearly alike after both craniotomy, in which the bone flap is replaced, and decompressive craniectomy, in which the bone flap is not replaced, at least not right away. (medscape.com)
  • While the outcomes are similar, the findings actually favor craniotomy because it eliminates the need for a second operation to repair the skull, said lead author Peter Hutchinson, MBBS, PhD, a neurosurgeon with the University of Cambridge in the United Kingdom, in an interview. (medscape.com)
  • CONCLUSIONS: A small craniotomy was not inferior to larger craniotomies in determining functional outcomes in the treatment of ASDH in the elderly. (minervamedica.it)
  • Herein, frozen tumors from 36 MGMT methylated patients grouped according to overall survival were extracted and proteins were profiled using surface-enhanced laser desorption/ionization (SELDI) with time-of flight (TOF) proteomics to identify low molecular weight proteins that associated with poor survival outcomes. (nature.com)
  • Proper medical attention can break this complicated cycle by providing patients with hope for improved functional outcomes necessary for accessing these services. (disabilityworks.org)
  • Few studies have looked at the role of rehabilitation and its effects on the improvement of functional outcomes in patients who have undergone surgery for subdural haematomas [4] . (physio-pedia.com)
  • Orthopaedic oncologists are able to pinpoint important molecular targets, forecast treatment outcomes, and personalise patient care plans by combining thorough genetic analysis, cutting-edge imaging tools, and interdisciplinary teamwork. (alliedacademies.org)
  • Clinicians can improve treatment selection, forecast treatment responses, and improve patient outcomes by utilising genetic profiling, molecular characterization, and specific patient characteristics. (alliedacademies.org)
  • Clinical and Radiographic Outcomes for Patients with Cervical Adjacent Segment Disease Treated with Anterior Cervical Discectomy and Fusion with Integrated Interbody Spacers. (duke.edu)
  • Hutchinson presented the findings from the Randomized Evaluation of Surgery With Craniectomy for Patients Undergoing Evacuation of Acute Subdural Hematoma (RESCUE-ASDH) trial at the annual meeting of the American Association of Neurological Surgeons (AANS) 2023. (medscape.com)
  • However, even patients with MGMT promoter methylated tumors eventually progress and succumb to their disease 10 . (nature.com)
  • We took an unbiased approach by selecting human GBM tumors that were MGMT methylated, responded initially to TMZ treatment, and grouped them according to patient survival. (nature.com)
  • Patients with tumors 2.5-3 cm in initial size went on to develop new or worsened symptoms 17% of the time. (medscape.com)
  • Due to the high risk of herniation, she underwent an emergent craniotomy and cesarean section at the same session. (ispub.com)
  • Obstetricians and anesthesiologists thought that there would be no problem about performing a cesarean section from the perspective of the fetus and a sectio was scheduled at the same session before the craniotomy. (ispub.com)
  • She underwent successful emergent Cesarean section followed by craniotomy. (surgicalneurologyint.com)
  • A single-center Puerto Rican population-based retrospective analysis was performed on consecutive patients treated for a CSDH at a designated institution from July 1, 2017 to December 31, 2019. (surgicalneurologyint.com)
  • Traumatic subdural hematoma often requires surgical evacuation using either craniotomy or decompressive craniectomy. (medscape.com)
  • The volume of intracerebral hematoma was calculated on CT scan images in all the patients except one (on MRI) according to ABC/XYZ volume estimation on the first imaging done [ 2 ]. (hindawi.com)
  • The new international, multicenter, pragmatic study recruited patients with traumatic acute subdural hematomas that needed evacuation. (medscape.com)
  • Presently, many patients with epilepsy are antiepileptic drug resistant or have systemic side-effects due to the antiepileptic drugs. (dovepress.com)
  • Published studies suggest that prophylactic administration of AEDs is unnecessary, especially in patients who are seizure free at the time of craniotomy. (cns.org)
  • Patient data such as age, gender, tissue diagnosis, and seizure history were collected over a period from January 2013 through June 2017. (cns.org)
  • Prophylactic treatment for seizure is not necessary in patients with no history of seizure. (medscape.com)
  • An emergent craniotomy had to be performed from the perspective of the neurosurgeons and neuroanesthesiologists. (ispub.com)
  • With limited ICU beds and the concern of viral transmission between patients and caregivers, many hospitals stopped non-emergent neurosurgical procedures for several weeks or months early in the pandemic then gradually resumed as COVID-dedicated wards were established [ 7 , 8 ]. (plos.org)
  • Postoperative cognitive dysfunction (POCD) will lower the quality of life, increase mortality and aggravate the financial and mental burden of patients. (researchsquare.com)
  • Preoperative preparations, as well as perioperative and postoperative monitoring, should be carefully observed to prevent complications that will adversely affect patients. (uns.ac.id)
  • After the clot was removed, patients were randomly assigned to undergo craniotomy or craniectomy. (medscape.com)
  • 78.1% men, 51.5% White, 44.1% Asian/Southeast Asian) could later undergo decompressive craniectomy if needed. (medscape.com)
  • At 12 months, 215 patients in the craniotomy group and 211 in the decompressive craniectomy group were evaluated. (medscape.com)
  • Further cranial surgery within 2 weeks was performed for 14.6% of the craniotomy group and 6.9% of the craniectomy group. (medscape.com)
  • By tailoring medications based on unique tumour characteristics, genetic profiles, and patient considerations, precision medicine promises to improve results. (alliedacademies.org)
  • Based upon this literature, we hypothesized that cessation of prophylactic AEDs in patients undergoing craniotomy does not result in a significant increase in seizures. (cns.org)
  • This research will help clinicians choose the appropriate prophylactic antibiotic for children undergoing craniotomies, with or without the presence of a preexisting shunt. (cns.org)
  • In patients with TN, preoperative neuroimaging should assess for brainstem lesions along the PTP. (thejns.org)
  • We retrospectively reviewed 34 patients with cerebral lesions who were referred for fMR imaging language mapping between January 1999 and July 2000. (ajnr.org)
  • Many systems require invasive surgery, with related high risks that not always overcome the benefits for the patients. (biorxiv.org)
  • A big step in this direction is developing endovascular neural interfaces since endovascular procedures are considerably less invasive, are routinely performed and allow for short patient recovery times. (biorxiv.org)
  • 1 Non-invasive localization techniques such as scalp electroencephalography (EEG), positron emission tomography (PET), magnetic resonance imaging (MRI), ictal single-photon emission computed tomography (SPECT), magnetoencephalography (MEG), and EEG-functional MRI (EEG-fMRI) can help in the identification of the EZ, which sometimes allows some patients to go directly on to resective surgery. (dovepress.com)
  • We describe an atypical case of a patient with no risk factors who developed sudden eclampsia and spontaneous intracerebral hemorrhage during the 34th week of pregnancy. (surgicalneurologyint.com)
  • 80.6% men, 53.4% White, 41.1% Asian/Southeast Asian), some patients underwent surgery to replace the missing skull section with titanium, synthetic material, or the original bone flap. (medscape.com)
  • The following section discusses how surgery could be an important part of qualifying for disability benefits in many patients' cases. (disabilityworks.org)
  • Topical vancomycin has emerged as an effective strategy to reduce the rate of SSI in patients undergoing spinal surgery including instrumentation. (neurologyindia.com)
  • Many studies have created grading systems to identify patients at high risk of CSDH recurrence after the initial surgery. (surgicalneurologyint.com)
  • Surgical considerations are germane because the percentage of patients with CSDH recurrence after initial surgery is relatively high (3-30% of cases). (surgicalneurologyint.com)
  • Precision medicine and personalised strategies are especially important in orthopaedic oncology because of the heterogeneity of tumours, the possibility of limb-sparing surgery, and the effect of treatment on patients' mobility and usefulness. (alliedacademies.org)
  • This kind of surgery requires a very qualified team and the cooperation of the patient , but has a significantly lower risk of neurological sequelae . (neuros.net)
  • These patients with refractory focal epilepsy may benefit from epilepsy surgery. (dovepress.com)
  • Both groups of patients will be fitted with a bispectral index (BIS) during surgery. (inasnacc.org)
  • Concerning previous surgery, 29 patients (30.2%) have had a myomectomy, 28 patients (29.1%) curettage,16 patients (16.6%) laparoscopy, eight (8.3%) hysteroscopy and one (1%) caesarean section. (bvsalud.org)
  • One half of patients who have seizures present with them. (medscape.com)
  • The most commonly used drug is phenytoin, especially for patients with generalized motor seizures. (medscape.com)
  • [ 2 ] Also, endovascular neural interfaces do not involve craniotomies, reducing the risks associated with the surgical procedure (e.g., susceptibility to seizures) and, therefore, increasing the possibility of patients undergoing these innovative treatments. (biorxiv.org)
  • Functional MR (fMR) imaging of word generation has been used to map Broca's area in some patients selected for craniotomy. (ajnr.org)
  • After 2 weeks in the ICU, the patient's Functional Independent Measure (FIM) score improved from 57 to 68 and was deemed appropriate for the in-patient rehabilitation unit. (physio-pedia.com)
  • This WebM&M describes an adverse event due to mislabeling or "syringe swap" in a preoperative patient. (ahrq.gov)
  • Preoperative evaluation for patients undergoing craniotomy should be carried out to determine the presence or absence of intracranial hypertension. (uns.ac.id)
  • 60% patients were managed conservatively, 36% underwent neurosurgical intervention, and 6% underwent radiological vascular intervention. (hindawi.com)
  • His clinical work was focused on providing perioperative care for neurosurgical patients. (wikipedia.org)
  • Detection of MGMT promoter methylation correlates strongly with clinical response to TMZ and is also a positive prognostic biomarker in TMZ-treated GBM, including in elderly patients 8 , 9 . (nature.com)
  • There has been considerable enthusiasm to use MGMT as a predictive biomarker for GBM patients, with the long-term scope for its use as a biomarker to assign alkylating therapy to individual patients, and it is an important stratification factor in current clinical trials. (nature.com)
  • The best neurological test is clinical evaluation, for which the patient has to be awake. (neuros.net)
  • Differences in the risk of deep-venous thrombosis and its complications, including risk of bleeding, between particular onco-logical patient groups suggests that there is a need for individual risk assessment and prophylaxis dedicated to specific clinical situations and patients. (viamedica.pl)
  • International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer. (viamedica.pl)
  • American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer. (viamedica.pl)
  • Lyman G, Kuderer N. Prevention and treatment of venous thromboembolism among patients with cancer: The American Society of Clinical Oncology Guidelines. (viamedica.pl)
  • This study aims to provide some epidemiological and clinical aspects of patients admitted to the emergency centre at Beni General Referral Hospital. (bvsalud.org)
  • The worldwide overall incidence of hospital adverse events approximates 10%, 5 with the OR being the most common site for incidents in the hospital setting, and errors occurring in up to 14.6% of surgical patients. (thejns.org)
  • In patients who underwent electrocortical stimulation (ECS) mapping of speech function during craniotomy while awake, the sites with speech function were compared with the locations of activation found during fMR imaging of word generation. (ajnr.org)
  • Research into the cortical organization of higher cognitive functions include language organization, memory and face processing involving electrical stimulation mapping in patients undergoing awake craniotomies and the use of optical imaging to localize areas of the neocortex serving specific cognitive processes. (duke.edu)
  • In 31 of 34 patients, activation was identified in the inferior frontal gyri or middle frontal gyri or both in Brodmann areas 9, 44, 45, or 46, unilaterally or bilaterally, with one or more of the tasks. (ajnr.org)
  • Recurrence in patients with glioblastoma (GBM) is inevitable resulting in short survival times, even in patients with O-6-Methylguanine-DNA Methyltransferase ( MGMT ) methylation. (nature.com)
  • Patients who scored higher on the scale had a higher risk of recurrence. (surgicalneurologyint.com)
  • They also give grounds for constant update of guidelines on prophylaxis in cancer patients. (viamedica.pl)
  • This document contains venous thromboembolism prophylaxis guidelines in oncology patients with focus on surgical cancer. (viamedica.pl)
  • 2 ] Stroke contributes to 12% of all maternal deaths,[ 16 ] and in patients with preeclampsia when the stroke is present, it accounts for 50% of all deaths related to cerebral complications in this group. (surgicalneurologyint.com)
  • Orthopaedic oncology is concerned with the diagnosis, therapy, and management of bone and soft tissue tumours, which frequently pose difficult problems because of the heterogeneity of the tumours, their varied aggressiveness, and the wide range of patient treatment reactions. (alliedacademies.org)
  • In all, 92 patients (95.8%) had abnormal intra uterine findings consisting of endometrial polyps (43.7%), sub-mucosal fibroids (42.7%), uterine cavity adhesions (20.8%), endometrial atrophy (4.1%), foetal bone (2%), uterine septum (1%) and non-absorbable suture thread (1%).Conclusion: Abnormal uterine findings were identified in 95.8% of patients attending hysteroscopy at GESHRTH. (bvsalud.org)
  • In vivo , combined ibudilast and TMZ treatment of a patient derived xenograft (PDX) model resulted in significantly longer overall survival. (nature.com)
  • Meta-regression analysis showed that the number of patients in a study, duration of follow-up, and year of publication did not contribute significantly to effect size. (neurologyindia.com)
  • In adult patients who received DIPRIVAN (2 mg/kg to 2.5 mg/kg), apnea lasted less than 30 seconds in 7% of patients, 30 seconds to 60 seconds in 24% of patients, and more than 60 seconds in 12% of patients. (guidelinecentral.com)
  • PATIENTS: Adult patients undergoing craniotomy. (bvsalud.org)
  • The first case involves a patient with a history of spinal stenosis who was admitted for elective cervical discectomy and cervical disc arthroplasty who went into cardiopulmonary arrest three days post-discharge and could not be intubated due to excessive airway swelling and could not be resuscitated. (ahrq.gov)
  • Symptoms improve in 70-80% of patients within 48 hours of the start of treatment. (medscape.com)
  • We discuss the management of this case and review the literature regarding the threshold for which initiation of antihypertensive treatment is indicated in pregnant patients. (surgicalneurologyint.com)
  • Orthopaedic oncology has been transformed by precision medicine and personalised treatments that adapt treatment plans to each patient depending on their particular characteristics. (alliedacademies.org)
  • Age, general health status, comorbidities, and treatment preferences are only a few of the patient-related factors taken into account by orthopaedic oncology personalised techniques. (alliedacademies.org)
  • Oncological treatment, surgeries, and advanced-stage cancer are only some risk factors for VTE, which is one of the most common causes of death in cancer patients. (viamedica.pl)
  • Most patients with MHA do not appear to have clinically significant bleeding problems, and specific treatment is not required. (medscape.com)
  • Most patients with MHA do not have clinically significant problems with bleeding and therefore do not require treatment. (medscape.com)
  • The patient was evaluated with standardized neuropsychological instruments before starting rehabilitation and again close to the discharge from treatment. (bvsalud.org)
  • Los síntomas de desconexión interhemisférica después de una lesión cerebral adquirida son inusuales en la práctica clínica actual. (bvsalud.org)
  • Primary multiple temporal cystic lesion, minimally en- human infection are E. granulosus and cerebral hydatid cysts are quite unu- hanced after contrast. (who.int)
  • Here, we presented the management of the patient throughout the perioperative period. (ispub.com)
  • This hybrid conference explored topics related to the theme of "Emerging Medical Technologies - A Patient Safety Perspective on Wearables, Big Data and Remote Care. (ahrq.gov)
  • Data regarding patients' characteristics, admission modality, stay duration, reason for admission, and discharge modality was anonymously collected from patients' registers. (bvsalud.org)
  • Important Safety Information: Radiation therapy is not appropriate for all patients. (elekta.com)
  • Acknowledgments: Dr. Cicero José Nunes Vaz (Physiatrist Doctor) and the other professionals of the Rehabili- tation Center who accompanied patient D. T. (the Physiotherapy, Occupational Therapy and Speech Therapy teams), with whom we had the opportunity to discuss the case and exchange valuable impressions for the plan- ning of the work and integration of the care for the patient. (bvsalud.org)
  • Until now, however, no such guidelines existed for the MRI-integrated operating room, which is a high-risk zone requiring standardized protocols to ensure the safety of both the patient and the operating room staff. (thejns.org)
  • Management of intracranial pressure control in reciprocal grade 3 astrocytoma patient should be paid attention to various things and consider the condition of the patients. (uns.ac.id)
  • It appears likely that craniotomy will be less expensive, since it avoids the second operation to replace the missing skull section, he said. (medscape.com)
  • Management of patients with intracranial hypertension can be guided by monitoring intracranial pressure (ICP) perioperatively. (uns.ac.id)
  • In this review article, the authors outline a pragmatic approach to patient assessment, arrhythmia diagnosis, and management of the most common arrhythmias seen in the CVICU. (bvsalud.org)
  • Background: Hysteroscopy is an essential tool to make intrauterine assessment in infertile patients. (bvsalud.org)
  • CT scan was done in 98% patients and MRI in 34%, while 6% underwent conventional angiography. (hindawi.com)
  • The study is designed to examine benefits associated with easily obtained CT imaging of the head at the point of care, instead of transporting the critical patient to a conventional scanner. (xorantech.com)
  • Forty-five patients underwent a small craniotomy, 47 a medium size, and 44 a large craniotomy. (minervamedica.it)
  • To our knowledge, the reliability and precision of these tasks in a large series of patients have not been reported. (ajnr.org)
  • Head trauma is the most important risk factor for the development of CSDH, with 50-80% of patients in large studies having a history of head trauma before presentation. (surgicalneurologyint.com)
  • The proposed subdural electrode system features attributes that could potentially translate into better icEEG recordings and allow sampling of large of areas of epileptogenicity at lower risk to patients. (dovepress.com)
  • In the operating room, the patient was noted to have a large "pulsatile mass," which was determined to be an aneurysm. (medscape.com)