AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth CareGeographicals
Coronary VesselsCoronary AngiographyCoronary Artery DiseaseCoronary CirculationAngioplasty, Balloon, CoronaryCoronary StenosisCoronary Artery BypassCoronary DiseaseCoronary VasospasmCoronary AneurysmCoronary ThrombosisMyocardial InfarctionCoronary RestenosisCoronary OcclusionPercutaneous Coronary InterventionCoronary Care UnitsRisk FactorsTreatment OutcomeStentsMyocardial IschemiaElectrocardiographyProspective StudiesFollow-Up StudiesTime FactorsUltrasonography, InterventionalCalcinosisDogsCoronary Artery Bypass, Off-PumpAngina, UnstableMyocardial RevascularizationPredictive Value of TestsVasodilator AgentsCardiac CatheterizationHemodynamicsPlatelet Aggregation InhibitorsVasodilationRisk AssessmentHeartTomography, X-Ray ComputedMyocardiumChest PainBlood Flow VelocityCollateral CirculationEndothelium, VascularAdenosineSwineRetrospective StudiesBiological MarkersSeverity of Illness IndexNitroglycerinExercise TestEchocardiographyDipyridamoleBlood PressureMyocardial ReperfusionPlaque, AtheroscleroticCardiovascular AgentsVascular ResistanceFractional Flow Reserve, MyocardialPrognosisSensitivity and SpecificityRecurrenceMucocutaneous Lymph Node SyndromeTiclopidineMicrocirculationVentricular Function, LeftMultidetector Computed TomographyAngina Pectoris, VariantMultivariate AnalysisTomography, Emission-Computed, Single-PhotonVasoconstrictionMyocardial Perfusion ImagingAspirinCohort StudiesVascular CalcificationErgonovineHyperemiaSinus of ValsalvaChi-Square DistributionMammary ArteriesMyocardial ContractionPostoperative ComplicationsCineangiographyIncidenceLogistic ModelsAngina, StableRadial ArteryTomography, Spiral ComputedCase-Control StudiesAcetylcholineThallium RadioisotopesArteriesHydroxymethylglutaryl-CoA Reductase InhibitorsAngioscopyProportional Hazards ModelsHeart VentriclesCholesterol, LDLContrast MediaHypercholesterolemiaDiabetic Angiopathies
AngiographyPrimary percutaneous coronary intLeft anteriBypass surgeryPercutaneous coronary interventionsMethodsCABGCardiacAngioplastyDiseaseArteriesAtrial fibrillationSTEMIAorticAcute myocardialElevation myocardialTicagrelorAntiplatelet therapyIntramural coronary arteryOral anticoagulationStentsStentInterventionsOutcomes in PatientsClinical outcomesElectiveIschemiaCatheterizationSurgeryRight coronaContrast-Induced NepRisk stratificationClopidogrelAntithrombotic therapy in patientsMajor Adverse Cardiovascular EventsMortality in patientsRenal artery sCardiopulmonaryCardiovascularIschemicVasculaturePrasugrelMedianFemoralTherapyInvasiveAngiogramsConcomitantIntervention
Angiography33
  • After they provided verbal assent and underwent coronary angiography, 296 patients in 7 U.K. centers were randomized through an interactive voice-response program to either in-hospital complete revascularization (n = 150) or IRA-only revascularization (n = 146). (nih.gov)
  • Little is known of the clinical significance of myocardial bridges, which may be recognised as the narrowing of the systolic coronary artery as seen in an angiography. (annals.edu.sg)
  • The angiographic data of 7200 adult patients undergoing coronary angiography were retrospectively analysed for the diagnosis of myocardial bridge. (annals.edu.sg)
  • Each of these patients with myocardial bridge was referred for angiography because of symptom of chest pain alone or symptom of chest pain, palpitations and dyspnoea. (annals.edu.sg)
  • Chest pain was the common reason for angiography in patients with myocardial bridge. (annals.edu.sg)
  • The primary outcome was SVG occlusion at 1 year, assessed with coronary computed tomography angiography, in all patients that had primary outcome imaging available. (eur.nl)
  • We sought to evaluate the prevalence and clinical relevance of significant abdominal vessel stenosis or aneurysm (AVA ) in patients undergo-ing coronary angiography. (jgc301.com)
  • 75-year old patients who underwent coronary angiography at two public institutions over a 12-month period were evaluated. (jgc301.com)
  • Angiographic results of patients who un-derwent coincident diagnostic abdominal aorta angiography to evaluate abdominal vessels on the basis of clinical and angiographic criteria were analyzed. (jgc301.com)
  • We aimed to determine the association between lymphopenia and mortality in patients presenting to coronary angiography and investigate whether elevated red blood cell distribution width (RDW), an established cardiovascular prognostic marker, further refines risk stratification. (viamedica.pl)
  • Retrospective analysis of patients undergoing coronary angiography for evaluation or treatment of coronary artery disease between 2003 and 2018. (viamedica.pl)
  • Overall, 15,179 patients aged 65 ± 12 years underwent coronary angiography. (viamedica.pl)
  • lymphopenia is associated with increased risk of mortality during long-term follow-up in patients undergoing coronary angiography, regardless of the coronary presentation. (viamedica.pl)
  • In this study, we aimed at investigate the association between plasma viscosity and platelet indices in patients undergoing coronary angiography. (maastrichtuniversity.nl)
  • Materials and methods: Three hundred and eighty four consecutive patients scheduled to undergo coronary angiography were included in the study. (maastrichtuniversity.nl)
  • Prior to coronary angiography, blood samples were withdrawn to determine routine biochemical markers, blood cell analyses and viscosity measurements. (maastrichtuniversity.nl)
  • Conclusion: We have shown for the first time that MPV correlates with plasma viscosity in patients undergoing coronary angiography, suggesting a relation with plasma proteins and activation of circulating platelets or peripheral consumption of platelets. (maastrichtuniversity.nl)
  • Objective: To determine the feasibility, safety, and clinical yield of angiographic screening among hypertensive patients undergoing coronary angiography. (elsevierpure.com)
  • Methods We did a randomised, multicentre, superiority trial comparing transradial against transfemoral access in patients with acute coronary syndrome with or without ST-segment elevation myocardial infarction who were about to undergo coronary angiography and percutaneous coronary intervention. (unipv.it)
  • Findings We randomly assigned 8404 patients with acute coronary syndrome, with or without ST-segment elevation, to radial (4197) or femoral (4207) access for coronary angiography and percutaneous coronary intervention. (unipv.it)
  • Of 97 such patients, about 44% underwent CAD/ischemia testing by invasive angiography, myocardial functional imaging, or both. (medscape.com)
  • These issues are "not very controversial" among cardiac electrophysiologists, Hussein said, but it remains "common practice" for other specialists to order angiography or ischemia testing for patients with monomorphic VT storm, typically in the cardiac care unit (CCU), before considering ablation. (medscape.com)
  • As reported, 10% of the cohort underwent coronary angiography after presentation with monomorphic VT storm, 26% had CT or PET myocardial functional imaging, and 9% had both tests. (medscape.com)
  • six of the latter went on to coronary angiography, the report states. (medscape.com)
  • A population of 135 patients who had undergone both myocardial technetium-99m-sestamibi rest-stress scintigraphy and coronary angiography within 3 months was studied. (lu.se)
  • The networks were trained to detect coronary artery disease in two vascular territories using coronary angiography as gold standard. (lu.se)
  • All consecutive patients with diabetes mellitus in Sweden who underwent percutaneous coronary intervention were entered into the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) during 2003-06 with complete follow-up for 1-4 years (median 2.5). (lu.se)
  • The aim of this case-control study was to examine the effect of music on the levels of anxiety, stress, and depression experienced by patients undergoing coronary angiography, as measured by the 21-item Depression Anxiety Stress Scales. (who.int)
  • coronary angiography who listen to music for 20 minutes have less stress, anxiety and Coronary angiography is a common inva- depression prior to and after angiography sive procedure for diagnosis of cardiovas- than those who do not listen to music? (who.int)
  • and noninvasive nursing intervention [ 2 ] to reduce stress and anxiety in patients under- Study design going coronary angiography. (who.int)
  • The study sample was patients who were working field into an increasingly evidence- scheduled for coronary angiography at a based treatment for various diseases [ 4 ]. (who.int)
  • Application of music therapy is based on were undergoing angiography and met the Rogers' Science of Unitary Human Beings inclusion criteria were invited to partici- theory [ 5 ]. (who.int)
  • Of 270 patients with non-STEMI, 213 underwent coronary angiography during hospitalization. (medscape.com)
Primary percutaneous coronary int5
Left anteri2
  • Myocardial bridge is more frequently found in the middle segment of the left anterior descending coronary artery. (annals.edu.sg)
  • Myocardial bridge was first described by Reyman in 1737 as an anatomical curiosity - the overlaying of the left anterior descending coronary artery by a myocardial bridge. (annals.edu.sg)
Bypass surgery11
  • CHICAGO (March 27, 2012) - Patients with coronary heart disease and their doctors have long been challenged by the decision of whether to pursue bypass surgery or opt for the less-invasive percutaneous coronary intervention (PCI, which includes stenting and balloon angioplasty). (acc.org)
  • The study analyzed health outcomes of 190,000 patients across the United States to compare the results of bypass surgery to those of PCI. (acc.org)
  • The study found that patients who underwent PCI had a higher death rate in the first four years after treatment than those who had opted for bypass surgery (20.8 percent and 16.41 percent, respectively). (acc.org)
  • Dr. Weintraub cautioned that the results do not mean bypass surgery is best for every patient. (acc.org)
  • The researchers combined patient data from the American College of Cardiology Foundation CathPCI database, the Society of Thoracic Surgeons CABG database and the Medicare claims database to compare survival rates among 86,000 bypass surgery patients and 103,000 PCI patients who underwent treatment from 2004-2008. (acc.org)
  • Should patients with asymptomatic mild or moderate aortic stenosis undergoing coronary artery bypass surgery also have valve replacement for their aortic stenosis? (bmj.com)
  • The maintenance of anesthesia in patients undergoing coronary artery bypass surgery can be achieved either by continuous intravenous administration of propofol or by inhaled volatile anesthetic gas such as sevoflurane. (hjn.gr)
  • Among patients undergoing coronary artery bypass surgery, the anesthesia with sevoflurane maintain better cardiac performance, suggesting that the sevoflurane may have cardioprotective effects during the cardiosurgery. (hjn.gr)
  • We aim to evaluate the association between syntax score and extracellular matrix histological characteristics of aortic punch tissue obtained during coronary artery bypass surgery (CABG). (opencardiovascularmedicinejournal.com)
  • This analysis compares coronary artery bypass surgery patients with High and Low syntax score which were followed up for one year period. (opencardiovascularmedicinejournal.com)
  • Adults who had undergone either coronary artery bypass surgery (CABS) or percutaneous coronary intervention (PCI) and participated in a rural CR programmes were recruited. (cdc.gov)
Percutaneous coronary interventions2
  • Short- and Mid-Term Outcomes of Complex and High-Risk Versus Standard Percutaneous Coronary Interventions in Patients Undergoing Transcatheter Aortic Valve Replacement. (qxmd.com)
  • We evaluated the outcomes of complex and high-risk percutaneous coronary interventions (CHIP-PCIs) and TAVR compared with standard PCI and TAVR. (qxmd.com)
Methods9
  • Methods Demographic, procedural and 12-month outcome data were prospectively collected for all patients undergoing PPCI in Leeds, UK, between 01 January 2009 and 31 December 2011, and 01 January 2013 and 31 December 2013. (whiterose.ac.uk)
  • METHODS: In this investigator-initiated, randomized, double-blind, placebo-controlled, multicenter trial, patients with ≥1 SVGs were randomly assigned (1:1) after CABG to ticagrelor or placebo added to standard aspirin (80 mg or 100 mg). (eur.nl)
  • METHODS AND RESULTS: A total of 445 patients with severe AS undergoing TAVI were included into a prospective registry between 2007 and 2012. (ox.ac.uk)
  • Patients and Methods: This study was a prospective cohort analysis of hypertensive patients who underwent cardiac catheterization at a tertiary care referral center from July 1998 to March 1999. (elsevierpure.com)
  • An exploration of proactive health oriented symptom patterns in patients undergoing percutaneous coronary intervention with stent implantation: A mixed-methods study protocol. (bvsalud.org)
  • This study is the first study to explore the symptom patterns and experiences of patients in various domains after stent implantation using a novel design including quantitative and qualitative methods , which will help the delivery of more specific patient management, reduce the recurrence of adverse cardiovascular events, and improve survival outcomes in the future . (bvsalud.org)
  • Methods: Economic evaluation of a multi-centre randomised trial comparing complete revascularisation at index admission to IRA-only P-PCI in patients with multi-vessel disease (12 month follow-up). (uea.ac.uk)
  • Methods and Results Data were analyzed from 4197 SIHD patients undergoing percutaneous coronary intervention (PCI). (elsevierpure.com)
  • Methods: We conducted a weighted meta-analysis of preoperative bridging studies published between 2002 and 2013 in patients with coronary stents undergoing surgery. (elsevierpure.com)
CABG22
  • Dr. Weintraub will present the study "Survival after PCI or CABG in Older Patients with Stable Multivessel Coronary Disease: Results from the ACCF-STS Database Collaboration on the Comparative Effectiveness of Revascularization Strategies" on Tuesday, March 27 at 8 a.m. at the Late-Breaking Clinical Trials V in McCormick Place North: Main Tent. (acc.org)
  • In the PLATO (Platelet Inhibition and Patient Outcomes) trial, patients who were assigned to ticagrelor and underwent coronary artery bypass graft surgery (CABG) had significantly lower total and cardiovascular mortality compared with those assigned to clopidogrel. (acc.org)
  • In the PLATO trial, 1,261 patients underwent CABG within 7 days after stopping the study drug. (acc.org)
  • This interesting study demonstrates that patients who had been treated with ticagrelor and then underwent CABG had lower mortality from both cardiovascular causes as well as infection and bleeding. (acc.org)
  • BACKGROUND: Approximately 15% of saphenous vein grafts (SVGs) occlude during the first year after coronary artery bypass graft surgery (CABG) despite aspirin use. (eur.nl)
  • The POPular CABG trial (The Effect of Ticagrelor on Saphenous Vein Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting Surgery) investigated whether ticagrelor added to standard aspirin improves SVG patency at 1 year after CABG. (eur.nl)
  • RESULTS: Among 499 randomly assigned patients, the mean age was 67.9±8.3 years, 87.1% were male, the indication for CABG was acute coronary syndrome in 31.3%, and 95.2% of procedures used cardiopulmonary bypass. (eur.nl)
  • Prediction scoring systems for coronary artery bypass grafting (CABG) patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) have not yet been reported. (biomedcentral.com)
  • This study was designed to develop a predictive score for in-hospital mortality for cardiogenic shock patients who received VA-ECMO after isolated CABG. (biomedcentral.com)
  • Retrospective cohort study of consecutive CABG patients supported with VA-ECMO ( n = 166) at the Beijing Anzhen Hospital between February 2004 and March 2017. (biomedcentral.com)
  • The REMEMBER score might help clinicians at bedside to predict in-hospital mortality for patients receiving VA-ECMO after isolated CABG for refractory cardiogenic shock. (biomedcentral.com)
  • Early identification of pre-ECMO factors associated with mortality may prognosticate in post-CABG patients. (biomedcentral.com)
  • In addition, prediction scoring systems for CABG patients on VA-ECMO have not yet been reported. (biomedcentral.com)
  • We developed the pRedicting mortality in patients undergoing veno-arterial Extracorporeal MEMBrane oxygenation after coronary artEry bypass gRafting (REMEMBER) score, which might help the clinicians to select patients that would benefit from VA-ECMO after CABG. (biomedcentral.com)
  • Patients were enrolled in the study if they received VA-ECMO treatment for refractory PCS after isolated CABG. (biomedcentral.com)
  • Volatile anesthetics induce cardioprotection in humans undergoing coronary artery bypass graft (CABG) surgery. (biomedcentral.com)
  • We hypothesized that helium induces pre- and postconditioning in CABG-patients, affecting signaling molecules protein kinase C-epsilon (PKC-ε), p38 mitogen activated protein kinase (p38 MAPK), extracellular signal-regulated kinase 1/2 (ERK-1/2) and heat shock protein 27 (HSP-27) within cardiac tissue, and reducing postoperative troponin levels. (biomedcentral.com)
  • After ethical approval and informed consent, 125 elective patients undergoing CABG surgery were randomised into this prospective, placebo controlled, investigator blinded, parallel arm single-centre study. (biomedcentral.com)
  • Helium pre- and postconditioning did not affect postoperative troponin release in patients undergoing CABG surgery. (biomedcentral.com)
  • Based on the experimental and first clinical data on helium conditioning we hypothesized that helium induces pre- and/or postconditioning in human myocardium of patients undergoing CABG surgery, involving regulation of PKC, p38 MAPK, ERK 1/2 and HSP-27, and reducing postoperative troponin T release. (biomedcentral.com)
  • We have reviewed the impact of evolving issues in coronary artery bypass grafting (CABG) on transfusion support for these patients. (northwestern.edu)
  • Patients with High (score ≥ 33, ( n =77)) and Low Syntax Scores (score ≤ 22, ( n =71)) undergoing elective CABG were recruited prospectively. (opencardiovascularmedicinejournal.com)
Cardiac11
  • For AMI patients undergoing PCI, TMZ reduced circulating biomarkers of myocardial infarction, reduced values of ALT, AST, and glucose, and improved cardiac function compared with the control group. (hindawi.com)
  • Moreover, an acute reload of atorvastatin even in the context of chronic statin has been associated with a significant reduction within 30 days of major adverse cardiac events after percutaneous coronary intervention. (univaq.it)
  • Finally, atorvastatin pretreatment may prevent the occurrence of atrial fibrillation in patients undergoing elective cardiac surgery. (univaq.it)
  • Most studies have shown the cardioprotective effects of the volatile anesthetic drugs in patients undergoing coronary artery surgery with and without extracorporeal circulation, referred decrease of the risk of heart attack and the mortality from any cause, higher cardiac index score, less length of stay both intensive care unit and hospital totally. (hjn.gr)
  • Congenital, inflammatory, metabolic, or degenerative disease may involve coronary circulation, and increasingly complex cardiac surgical repairs demand enhanced understanding to improve operative outcomes. (medscape.com)
  • The Latin term corona, or crown, aptly describes coronary arteries that supply cardiac parenchyma with nutrient blood flow. (medscape.com)
  • All patients who underwent cardiac surgery between June 2005 and December 2008 were included. (who.int)
  • Acute kidney injury following cardiac surgery is a serious problem among patients in eastern Saudi Arabia. (who.int)
  • Aims and Objectives: To determine whether a weight management intervention (WMI) plus cardiac rehabilitation (CR) compared to CR alone improves outcomes for overweight and obese cardiac revascularisation patients. (cdc.gov)
  • Background: Despite participating in cardiac rehabilitation (CR), few cardiac patients lose enough weight to achieve clinically significant cardiovascular disease risk reduction. (cdc.gov)
  • Coronary anomalies may be commonly associated with other congenital cardiac malformations, most notably, transposition of the great arteries, tetralogy of Fallot malformation, and different forms of pulmonary atresia. (medscape.com)
Angioplasty6
  • primary percutaneous coronary angioplasty. (nih.gov)
  • In 2003, approximately 84% of the 660,000 hospitalized patients who underwent a coronary angioplasty received a stent, a wire mesh tube inserted during angioplasty to reduce future narrowing of arteries. (cdc.gov)
  • Black and white angioplasty patients were equally likely to receive a stent. (cdc.gov)
  • Regarding the procedures, 23.1% of the patients underwent femoral angioplasty and 15.4% of the radial angioplasty, and 23.6% of the patients, respectively, and myocardial revascularization. (bvsalud.org)
  • To compare the care provided to infarcted patients submitted to Bruna Eduarda Schreiner de angioplasty before and during the COVID-19 pandemic. (bvsalud.org)
  • Patients who underwent a single-catheter coronary angioplasty through the femoral artery in the groin area. (who.int)
Disease40
  • Trimetazidine (TMZ) is effective at improving clinical outcomes in chronic heart failure and stable coronary artery disease patients. (hindawi.com)
  • A sedentary lifestyle and poor cardiorespiratory fitness are independent risk factors for coronary atherosclerotic heart disease [ 8 ]. (hindawi.com)
  • In patients presenting for P-PCI with multivessel disease, index admission complete revascularization significantly lowered the rate of the composite primary endpoint at 12 months compared with treating only the IRA. (nih.gov)
  • Coronary heart disease - the leading cause of death in the United States - occurs when a fatty buildup narrows or blocks the heart's arteries. (acc.org)
  • This study should help inform decision making concerning the choice of revascularization in patients with stable ischemic heart disease. (acc.org)
  • The aim of this study was to emphasize the impact of the aspartate aminotransferase-to-alanine aminotransferase ratio (De Ritis ratio) on the prognosis of patients with stable coronary artery disease (SCAD) undergoing percutaneous coronary intervention (PCI). (medscimonit.com)
  • Objectives Early and accurate diagnosis of peripheral atherosclerosis is of paramount importance for global management of patients with known coronary artery disease (CAD), especially in the elderly. (jgc301.com)
  • Results During the study period, AVA was found in 90 (35.7%) of 252 con-secutive patients (185 males, mean age 79 ±5.8 years), renal artery stenosis in 13.1% of cases (33 patients), aort-oiliac artery disease in 13.7 % (35 patients), and aortic aneurismal disease in 8.9% (22 patients). (jgc301.com)
  • Coronary artery disease severity and aortic stenosis: clinical outcomes according to SYNTAX score in patients undergoing transcatheter aortic valve implantation. (ox.ac.uk)
  • AIM: The aim of this study was to evaluate whether coronary artery disease (CAD) severity exerts a gradient of risk in patients with aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI). (ox.ac.uk)
  • Chronotropic incompetence is common in patients with cardiovascular disease and is associated with increased risk of adverse events. (unina.it)
  • We assessed the incremental prognostic value of heart rate reserve (HRR) over stress myocardial perfusion single-photon emission computed tomography (MPS) findings in patients with suspected coronary artery disease (CAD). (unina.it)
  • A large number of randomized trials have established the beneficial effects of statins for primary and secondary prevention of coronary artery disease. (univaq.it)
  • The prevalence of coronary artery disease (CAD) in patients undergoing TAVR varies and is associated with increased morbidity and mortality. (qxmd.com)
  • Overview of Coronary Artery Disease Coronary artery disease (CAD) involves impairment of blood flow through the coronary arteries, most commonly by atheromas. (msdmanuals.com)
  • Coronary Heart Disease (CHD) is one of the most prevalent chronic diseases worldwide. (bvsalud.org)
  • This study aimed to identify the clinical factors and anatomical features associated with SI in patients with stable ischemic heart disease (SIHD). (elsevierpure.com)
  • Patients with a severe form of ventricular arrhythmia who may be referred for catheter ablation are often first tested for coronary artery disease (CAD) or ischemia. (medscape.com)
  • The findings "argue against performing routine evaluations to rule out coronary [disease] or myocardial ischemia as culprits in monomorphic VT storm" in patients without evidence of ACS, write Feras Alkhalaileh, MD, Heart and Vascular Institute, Cleveland Clinic, Ohio, and colleagues in their report published August 2 in JACC: Clinical Electrophysiology . (medscape.com)
  • To address possible concerns about selection bias in the main cohort, all of whom underwent ablation, a secondary analysis was conducted with 91 patients with known asymptomatic coronary disease and monomorphic VT storm who were selected from the registry without regard to whether they underwent catheter ablation. (medscape.com)
  • Knowledge of physiology, normal and variant anatomy, and anomalies of coronary circulation is an increasingly vital component in managing congenital and acquired pediatric heart disease. (medscape.com)
  • Variations in coronary anatomy are often recognized in association with structural forms of congenital heart disease. (medscape.com)
  • Based on his father's history of early onset heart disease, John underwent a battery of genetic tests. (cdc.gov)
  • He was found to be at increased risk of coronary artery disease, colon cancer, and lung cancer. (cdc.gov)
  • By 2010, the field of pharmacogenomics has blossomed, and a prophylactic drug regimen based on the knowledge of John's personal genetic data can be precisely prescribed to reduce his cholesterol level and the risk of coronary artery disease to normal levels. (cdc.gov)
  • One hundred patients were randomly assigned to receive a family history report (FH group, 50 patients) or in combination with a WGS report (FH + WGS group, 50 patients), which included monogenic disease risk (MDR) results (associated with Mendelian disorders), carrier variants, pharmacogenomic traits, and polygenic risk estimates for common disease traits. (cdc.gov)
  • The authors found previously unsuspected genetic disease results in more than 20% of patients (11/50). (cdc.gov)
  • All 50 patients carried at least one genetic variant associated with a recessive genetic disease, and 96% carried a pharmacogenomic variant predicting a nonstandard response to one or more medications. (cdc.gov)
  • The purpose of the present study was to develop a computer-based method for automatic detection and localization of coronary artery disease in myocardial bull's-eye scintigrams. (lu.se)
  • Artificial neural networks can detect coronary artery disease in myocardial bull\u2019s-eye scintigrams with such a high accuracy that the application of neural networks as clinical decision support tools appears to have significant potential. (lu.se)
  • Patients with diabetes mellitus have more extensive coronary artery disease, more disease progression, and restenosis. (lu.se)
  • This real-life registry study shows that restenosis was halved by DES in diabetic patients with stable or unstable coronary disease, with similar risk of death or MI up to 4 years compared with BMS. (lu.se)
  • Patients with Williams syndrome (elfin facies, infantile hypercalcemia, hypoplastic teeth) may have coronary ostial narrowing as a component of supravalvar aortic stenosis characteristic of this disease. (medscape.com)
  • Patients with aortic valve disease commonly have variants in ostial origin. (medscape.com)
  • Genetic Testing Enables the Diagnosis of Familial Hypercholesterolemia Underdiagnosed by Clinical Criteria: Analysis of Japanese Early-Onset Coronary Artery Disease Patients. (cdc.gov)
  • Prevalence of Diabetes and Its Association with Atherosclerotic Cardiovascular Disease Risk in Patients with Familial Hypercholesterolemia: An Analysis from the Hellenic Familial Hypercholesterolemia Registry (HELLAS-FH). (cdc.gov)
  • Genetics, coronary artery disease, and myocardial revascularization: will novel genetic risk scores bring new answers? (cdc.gov)
  • Effects of the ABCB1 C3435T single nucleotide polymorphism on major adverse cardiovascular events in acute coronary syndrome or coronary artery disease patients undergoing percutaneous coronary intervention and treated with clopidogrel: A systematic review and meta-analysis. (cdc.gov)
  • If patients suffer from severe visual impairment, a changed mental state, skin conditions linked to cold sensitivity (such as Raynaud's disease), sensory-motor deficiency, diabetes, neuropathy, and scar tissue from burns, wounds, or other injuries surrounding the sheath site. (who.int)
  • Use of internal swabs or pledgets soaked in vasoconstrictors is contraindicated in patients with uncontrolled hypertension or coronary artery disease. (medscape.com)
Arteries9
  • Also, 53% of patients had normal renal arteries, 28% had stenoses less than 50%, and 19.2% had stenoses of 50% or more. (elsevierpure.com)
  • Coronary arteries (most often two) are normally the only vessels arising immediately above the free margin of aortic valve from the ascending aorta. (medscape.com)
  • The normal anatomy of the coronary arteries is shown in the image below. (medscape.com)
  • Normal anatomy of coronary arteries, viewed from above with the atria removed. (medscape.com)
  • The left coronary ostium is usually single, giving rise to a short, common LCA trunk that branches into the left anterior descending (LAD) and circumflex (Cx) coronary arteries. (medscape.com)
  • It is frequently observed in association with anomalous origin of the left coronary artery (LCA) from the right sinus of Valsalva and coursing between the 2 great arteries. (medscape.com)
  • Coronary arteries in transposition of the great arteries normally arise from facing sinuses of Valsalva. (medscape.com)
  • Thirteen patterns of origin and proximal epicardial course of coronary arteries in 255 hearts with complete transposition of the great arteries. (medscape.com)
  • According to Pasquini, this anomaly may be suggested on echocardiographic study by the eccentric origin of the coronary ostia arising away from the middle third of the aortic sinus and coursing within the aortic wall (see Transposition of the Great Arteries). (medscape.com)
Atrial fibrillation3
STEMI2
  • We sought to assess the association of choice of oral P2Y12-receptor inhibitor with clinical outcomes following PPCI for STEMI in a large consecutive patient series. (whiterose.ac.uk)
  • Of the cohort, 72 had acute ST-segment-elevation MI (STEMI), 25 of whom underwent primary PCI while 24 received fibrinolytic therapy. (medscape.com)
Aortic2
  • Between January 2014 and March 2021, a total of 276 consecutive patients with severe aortic stenosis (AS) who underwent TAVR and PCI at 3 centers within Northwell Health were retrospectively reviewed. (qxmd.com)
  • The left coronary artery (LCA) arises from the mid position of the left (left anterior) sinus of Valsalva (sinuses on either side of the point of aortic and pulmonary commissural contact) just above the level of the free margin of the aortic valve leaflet and generally below the sinotubular junction. (medscape.com)
Acute myocardial4
Elevation myocardial2
  • This article briefly reviews the physiopathological mechanisms of thrombosis and presents an overview of the available literature supporting the use of these major drugs, as well as the European Society of Cardiology recommendations for their utilisation in the setting of non-ST and ST-elevation myocardial infarction undergoing invasive treatment. (univr.it)
  • The randomisation sequence was computer generated, blocked, and stratified by use of ticagrelor or prasugrel, type of acute coronary syndrome (ST-segment elevation myocardial infarction, troponin positive or negative, non-ST-segment elevation acute coronary syndrome), and anticipated use of immediate percutaneous coronary intervention. (unipv.it)
Ticagrelor4
  • Brilinta (ticagrelor) is prescribed to reduce the risk of cardiovascular death, heart attacks and strokes in patients with acute coronary syndrome (ACS), or by those with history of heart attacks. (aboutlawsuits.com)
  • Among patients undergoing coronary artery bypass graft surgery, adding ticagrelor to aspirin was associated with a significantly decreased risk of vein graft failure," the researchers concluded. (aboutlawsuits.com)
  • Nevertheless, the findings of this study mirror the survival benefit that was demonstrated in the overall PLATO trial, and suggest a greater role for ticagrelor in patients with acute coronary syndromes. (acc.org)
  • Primary outcome imaging was available in 220 patients in the ticagrelor group and 223 patients in the placebo group. (eur.nl)
Antiplatelet therapy5
  • In a report published this month in the Journal of the American Medical Association (JAMA) , researchers from Canada, Europe and the U.S. indicate that Brilinta dual antiplatelet therapy (DAPT) is nearly three times as likely to cause significant bleeding events than aspirin, when given as a blood thinner following coronary artery bypass graft surgery. (aboutlawsuits.com)
  • OAC in AF patients reduces the risk of stroke and systemic thromboembolism (SE) by more than 60% demonstrating superiority over aspirin monotherapy or clopidogrel-based dual antiplatelet therapy (DAPT) (10). (hungarica.eu)
  • Efficacy and safety of single vs dual antiplatelet therapy in patients on anticoagulation undergoing percutaneous coronary intervention: A systematic review and meta-analysis. (bvsalud.org)
  • Algorithm for Oral Anticoagulation or Antiplatelet Therapy in Patients Undergoing TAVI and Recent Co. (radcliffecardiology.com)
  • Background: Preoperative bridging with a glycoprotein IIb/IIIa inhibitor is often performed in patients with prior coronary stents undergoing surgery who require antiplatelet therapy discontinuation, but its safety and efficacy have received limited study. (elsevierpure.com)
Intramural coronary artery2
  • Myocardial bridge, intramural coronary artery, coronary artery over bridging and myocardial loop are essentially the different terms used to designate the same phenomenon. (annals.edu.sg)
  • The presence of an intramural coronary artery course in this condition may complicate arterial switch operation. (medscape.com)
Oral anticoagulation2
Stents4
  • Brilinta is also commonly used to reduce the rate of stent thrombosis in patients who have received stents for treatment of ACS. (aboutlawsuits.com)
  • We performed a weighted meta-analysis of the outcomes in patients with coronary stents undergoing bridging with glycoprotein IIb/IIIa inhibitors prior to surgery. (elsevierpure.com)
  • The use of drug-eluting stents (DES) in these patients is widespread, despite uncertain long-term safety and efficacy. (lu.se)
  • Patients who received at least one DES (n = 4754) were compared with those who received only bare metal stents (BMS) (n = 4956) at the index procedure. (lu.se)
Stent5
  • However, white patients were more likely than black patients to receive a drug-eluting stent. (cdc.gov)
  • Currently, percutaneous coronary intervention (PCI) with stent implantation is the main clinical treatment for CHD, and patients can achieve better outcomes after stenting. (bvsalud.org)
  • Longitudinal research , including surveys regarding three different periods, will be sued to describe the symptom patterns of patients undergoing PCI with stent implantation, clarifying their focused symptom problems during different time periods or in populations with different features. (bvsalud.org)
  • Conclusions: Preoperative bridging with a glycoprotein IIb/IIIa inhibitor in patients undergoing surgery after coronary stenting does not abolish the risk of perioperative stent thrombosis and may carry increased risk for bleeding. (elsevierpure.com)
  • Myocardial infarction was significantly less common with DES in patients who received only one stent RR, 0.80 (95% CI, 0.66-0.96). (lu.se)
Interventions1
  • Institutions with coronary artery bypass grafting programs should establish a multidisciplinary approach to use a combination of interventions designed to minimize homologous blood exposure. (northwestern.edu)
Outcomes in Patients2
Clinical outcomes1
  • The PROTECT III study demonstrates improved completeness of revascularization, less bleeding, and improved 90-day clinical outcomes compared to PROTECT II for Impella-supported HRPCI among patients with severely depressed LVEF. (physiciansweekly.com)
Elective2
Ischemia5
  • SCAD was defined as epicardial coronary artery diameter stenosis ≥90% or epicardial coronary artery diameter stenosis ≥75% accompanied by symptoms or stress-induced myocardial ischemia. (medscimonit.com)
  • The findings, they say, question such routine CAD/ischemia testing in patients like those studied, who had episodes of monomorphic ventricular tachycardia (VT) storm but not an acute coronary syndrome (ACS) and ultimately went to ablation. (medscape.com)
  • It's "reasonable" to test for CAD or ischemia in patients with polymorphic VT storm, which is likely ischemia-driven, he observed. (medscape.com)
  • Coronary ischemia is felt to arise from disturbed kinetics from oblique origin, ostial stenosis, compression of intramural course, loss of reservoir capacity, and increased myocardial oxygen demands associated with exercise. (medscape.com)
  • In infancy with coronary ischemia, patients present with signs of CHF and low output. (medscape.com)
Catheterization3
  • Conclusion: The prevalence of incidental renal artery stenosis among hypertensive patients undergoing coronary catheterization is significant. (elsevierpure.com)
  • Regarding the exams, 69.2% underwent radial catheterization. (bvsalud.org)
  • Individuals undergoing peripheral catheterization. (who.int)
Surgery12
  • The purpose of this study was to evaluate the effect of different surgical variables, such as perfusion duration and number of grafts, on resistance and reactance, in heart surgery patients. (isciii.es)
  • While Brilinta decreases the risk of vein graft failure following coronary artery bypass graft surgery, the findings of a new study also warns side effects of the blood thinner may increase the risk of serious bleeding events for those patients. (aboutlawsuits.com)
  • Another study published in 2016 indicated patients taking Brillinta before heart surgery faced an increased risk of up to 20% for bleeding events . (aboutlawsuits.com)
  • Combining data from several large databases, we found that survival was better with coronary surgery than percutaneous coronary intervention. (acc.org)
  • It does push the needle toward coronary surgery, but not overwhelmingly so," said Dr. Weintraub. (acc.org)
  • When we're recommending coronary surgery to patients, even though it is a bigger intervention than PCI, we can now have a little more confidence that the decision is a good one. (acc.org)
  • Survival was better with coronary surgery for all patient subgroups. (acc.org)
  • Sixteen patients scheduled for coronary artery bypass grafting surgery with hypothermic cardiopulmonary bypass gave their informed consent to participate in an open-label dose-escalation study (0, 20, 35, 50% xenon in oxygen and air). (asahq.org)
  • The heart rates of patients did not differ significantly, since the decrease of the heart rates preoperative until the first hour from the beginning of the surgery was greater to the sevoflurane group. (hjn.gr)
  • The 30-day coprimary outcomes were major adverse cardiovascular events, defined as death, myocardial infarction, or stroke, and net adverse clinical events, defined as major adverse cardiovascular events or Bleeding Academic Research Consortium (BARC) major bleeding unrelated to coronary artery bypass graft surgery. (unipv.it)
  • Efficacy and Safety of Vorapaxar in Non-ST-Segment Elevation Acute Coronary Syndrome Patients Undergoing Noncardiac Surgery. (thecvc.ca)
  • Propofol is also used to sedate individuals who are receiving mechanical ventilation but not undergoing surgery, such as patients in the intensive care unit. (wikipedia.org)
Right corona2
  • The right coronary artery (RCA) most commonly arises separately from an ostium just below the sinotubular junction of the right (right anterior) sinus of Valsalva. (medscape.com)
  • Sudden death is less commonly seen in association with anomalous origin of the right coronary artery (RCA) from the left sinus of Valsalva. (medscape.com)
Contrast-Induced Nep1
Risk stratification3
  • A high De Ritis ratio was an independent and valuable risk stratification factor for MACCE and all-cause mortality in patients with SCAD after PCI. (medscimonit.com)
  • Hence, the evaluation of HRR may further improve patients' risk stratification. (unina.it)
  • Therefore, risk stratification after acute coronary syndrome needs to consider not only age but also frailty and comorbidity. (medscape.com)
Clopidogrel3
  • The consistency across randomized controlled trials on combination therapy with non-vitamin K antagonist oral anticoagulant (NOAC) and clopidogrel, including patients with acute coronary syndromes, led to changes in everyday practice. (hungarica.eu)
  • Traditionally TAT involving vitamin K antagonist (VKA), mostly warfarin, aspirin and clopidogrel was administered for 6-12 months to reduce the risk of stroke (with VKA) and coronary thrombotic events (with antiplatelet drugs) (3). (hungarica.eu)
  • Post-Percutaneous Coronary Intervention CYP2C19 Genotyping in an Irish population: The Potential Role in Identifying Clopidogrel Therapy Related Bleeding Risks. (cdc.gov)
Antithrombotic therapy in patients1
  • Decision making on the length and intensity of antithrombotic therapy in patients with AF and PCI is based on the predicted risk of thromboembolism and bleeding. (hungarica.eu)
Major Adverse Cardiovascular Events1
  • This review aims to examine the relationship between baseline anemia and mortality, Major Adverse Cardiovascular Events (MACE) and major bleeding in patients undergoing PCI. (elsevierpure.com)
Mortality in patients1
  • Chronotropic incompetence has independent and incremental prognostic value in predicting all-cause mortality in patients with suspected CAD undergoing exercise stress-MPS. (unina.it)
Renal artery s1
  • Patients with renal artery stenosis were more likely to have had a previous coronary intervention. (elsevierpure.com)
Cardiopulmonary2
  • Before embarking on a randomized clinical trial to test the safety and efficacy of xenon for postoperative neurocognitive deficit, we undertook a phase I study to investigate the safety of administering xenon to patients undergoing coronary artery bypass grafting while on cardiopulmonary bypass and to assess the practicability of our xenon delivery system. (asahq.org)
  • Xenon was safely and efficiently delivered to coronary artery bypass grafting patients while on cardiopulmonary bypass. (asahq.org)
Cardiovascular5
  • Conclusions Aged patients with multivessel CAD frequently have a high risk profile and multiple vascular atherosclerotic distributions, suggesting the usefulness of a more global and compre-hensive cardiovascular approach in aged patients. (jgc301.com)
  • 22 receive less complete revascularization and have a higher risk of cardiovascular death, stroke, or MI than patients without CAD or low SS. (ox.ac.uk)
  • Therefore, screening abdominal aortography should be considered in these patients to better define their risk of cardiovascular complications. (elsevierpure.com)
  • Patients with a history of heart failure, stroke, or anginal symptoms with Canadian Cardiovascular Society class 2 or more were more likely to have SI (odds ratio [OR] 1.63, p = 0.025, OR: 1.85, p = 0.009, and OR: 1.49, p = 0.003, respectively). (elsevierpure.com)
  • Natural Persons of Brazil, from March 16 to May siology of SARS-COV-2, this research aimed to 31, 2020, 15,870 people died from cardiovascular compare the care provided to infarcted patients diseases (CVD) at home. (bvsalud.org)
Ischemic2
  • NOAC DAT might entail clinically important higher ST occurrence, warranting a case-by-case comprehensive evaluation that integrates patient- and procedure-related residual ischemic risk with the patient-specific bleeding risk. (unito.it)
  • Revascularization for Acute Coronary Syndromes Revascularization is the restoration of blood supply to ischemic myocardium in an effort to limit ongoing damage, reduce ventricular irritability, and improve short-term and long-term outcomes. (msdmanuals.com)
Vasculature1
  • Correct identification of the origin and course of coronary vasculature is important for patients undergoing Jatene arterial switch procedure. (medscape.com)
Prasugrel2
  • Prasugrel is a potent thienopyridine that may be preferentially used in younger patients with lower bleeding risk. (nih.gov)
  • Age is a strong determinant of clinical risk as well as prasugrel prescription in ACS PCI with much lower use among older patients. (nih.gov)
Median2
  • Among 204 patients with SCAD undergoing PCI, during a median follow-up period of 706 days (24 months), 13.7% (28/204) patients experienced MACCE, and 8.8% (18/204) experienced all-cause mortality. (medscimonit.com)
  • During a median follow-up of 8 years, 4253 patients died. (viamedica.pl)
Femoral4
  • Summary Background It is unclear whether radial compared with femoral access improves outcomes in unselected patients with acute coronary syndromes undergoing invasive management. (unipv.it)
  • Patients were randomly allocated (1:1) to radial or femoral access with a web-based system. (unipv.it)
  • Interpretation In patients with acute coronary syndrome undergoing invasive management, radial as compared with femoral access reduces net adverse clinical events, through a reduction in major bleeding and all-cause mortality. (unipv.it)
  • After putting the patient in a supine position and removing the femoral sheath, a tiny dressing is applied over the insertion site, cold therapy is administered by applying pressure for 20 minutes, and the Visual Analogue Scale (VAS) is used to measure the pain intensity for the patients. (who.int)
Therapy7
  • The use of dabigatran, rivaroxaban, or apixaban in combination with antiplatelet agents lowers the risk of major bleeding and makes it an option preferred over triple therapy in the majority of PCI patients with AF. (hungarica.eu)
  • The present review summarizes available data on the efficacy and safety of antithrombotic therapy in AF patients undergoing PCI in the era of NOAC. (hungarica.eu)
  • The most frequent indication for double or triple antithrombotic therapy (DAT, TAT), including a P2Y12 inhibitor with or without aspirin and an oral anticoagulant (OAC), is an acute coronary syndrome (ACS) with concomitant AF, mechanical heart valves, left ventricular thrombus, or recent venous thromboembolism (2). (hungarica.eu)
  • Therefore, antithrombotic therapy to modulate either pathway plays an important role for the reduction of ischaemic adverse events in ACS patients. (univr.it)
  • Nitroglycerin is preferable to morphine , which should be used judiciously (eg, if a patient has a contraindication to nitroglycerin or is in pain despite nitroglycerin therapy). (msdmanuals.com)
  • A comprehensive literature search for studies comparing triple antithrombotic therapy (TAT) vs double antithrombotic therapy (DAT) in patients requiring OAC undergoing PCI was performed in clinicalTrials.gov, PubMed , Web of Science , EBSCO Services, Cochrane Central Register of Controlled Trials, Google Scholar, and various scientific conference sessions from inception to May 1st, 2019. (bvsalud.org)
  • Patients music therapy have produced different re- with the following characteristics were sults. (who.int)
Invasive3
  • Despite substantial progress in pharmacotherapeutic and invasive treatments [ 5 - 7 ] in recent decades, successful treatment of AMI and the disturbances of the endocrine system accompanied by AMI remains elusive for many patients. (hindawi.com)
  • Patients and doctors tend to choose the less-invasive PCI when both treatments are an option. (acc.org)
  • The results found reflect the profile of the patient admitted to the Intensive Care Unit and the use of invasive procedures to obtain the diagnosis and the targeted care of the SCA. (bvsalud.org)
Angiograms2
  • All coronary angiograms were reviewed independently by at least 2 of the authors and the case was included only if there was a consensus that the myocardial bridge resulted in 50% narrowing or more. (annals.edu.sg)
  • The preoperative SYNTAX score (SS) was determined from baseline coronary angiograms. (ox.ac.uk)
Concomitant1
  • Our study suggests that CHIP-PCI can be safely performed in patients with complex CAD and concomitant severe AS. (qxmd.com)
Intervention16