AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation ScienceHealth Care
Clot RetractionBlood CoagulationFibrinFibrinolysisThrombelastographyTissue Plasminogen ActivatorThrombosisFibrinogenFactor XIIIaBlood Coagulation TestsUltrasonic TherapyHemostaticsFibrinolytic AgentsHemoglobin HPlasminogenPulmonary EmbolismHigh-Intensity Focused Ultrasound AblationHemostasisalpha-2-AntiplasminFibrinolysinFactor XIIIBlood Coagulation DisordersThrombinIntracranial EmbolismCerebral HemorrhageStreptokinaseThrombolytic TherapySubarachnoid HemorrhagePlatelet ActivationBlood PlateletsBloodPlasminogen ActivatorsHeparinRabbitsHemorrhageTime FactorsDogsDisease Models, AnimalRecombinant ProteinsFibrin Clot Lysis TimeStrokeTreatment OutcomeSwineKineticsFibrinogens, AbnormalCarboxypeptidase UNephelometry and TurbidimetryIntracranial ThrombosisFibrinopeptide BFibrin Fibrinogen Degradation ProductsThrombin TimeUrokinase-Type Plasminogen ActivatorBatroxobinAfibrinogenemiaMechanical ThrombolysisFibrinopeptide AFactor XIII DeficiencyWhole Blood Coagulation TimePlatelet AggregationCoagulantsThrombectomyAnticoagulantsPlasmaThromboplastinVenous ThrombosisHirudinsBlood Coagulation FactorsMicroscopy, Electron, ScanningIntracranial Embolism and ThrombosisCarboxypeptidase BHydroxyethyl Starch DerivativesPlatelet Glycoprotein GPIIb-IIIa ComplexPipecolic AcidsCerebral AngiographyBleeding TimePolygelinePartial Thromboplastin TimeFemoral VeinEmbolectomyAntifibrinolytic AgentsPlasma SubstitutesKaolinFactor XaPlasminogen InactivatorsElasticityTransglutaminasesProthrombin TimeCarotid Artery ThrombosisTomography, X-Ray ComputedThromboembolismMolecular Sequence DataProthrombinSuctionHemophilia AAminocaproatesInfarction, Middle Cerebral ArteryExtravasation of Diagnostic and Therapeutic MaterialsAntithrombinsShock, TraumaticDisseminated Intravascular Coagulation
Deep Vein ThromPulmonaryLungsPlateletsSerious blood clotsVesselsLife-Threatening Blood ClotsAnticoagulantsOccurs when a blood clot formsVenousMedicationsDissolveThinners to preventPreventionResearchersHeparin2022ThrombosisRisk for a blood clotSymptoms of a blood clotKnee replace2023ThinnerPreventableInflammationAspirinCOVIDOccurWarfarinPotentiallyRisksHormonalSurgeryInferior venaVesselAbnormalAntiplateletProteinClumpVeinsPatient'sCompression stockingsStrokesLawsuitsVaccinationHelp preventStrokeDrugsBloodstreamFatalIron deficiencyDiagnosisInterventionTreatmentMoleculeOutcomesAnticoagulationDeathsEstrogenFormationRivaroxabanSignsScientistsFormAffectsExcessiveAtrial Fibrillation
Deep Vein Throm11
Pulmonary26
Lungs24
  • After knee surgery, there's a risk of blood clots in the legs or lungs. (sciencedaily.com)
  • When the team examined the lungs of the patients who died, they found tiny clots of tangled NETs and blood platelets known as microthrombi scattered through the tissue. (news-medical.net)
  • That's one conclusion of a PCORI-funded study on venous thromboembolism (VTE), or blood clots, which usually occur in the leg but can break off and lodge in the lungs. (pcori.org)
  • Blood clots in the lungs kill more than two thousand people each year in the UK alone yet how they form is still largely unknown until now. (news-medical.net)
  • We knew that clots in the lungs can arise from clots in the deep veins of the legs or arms, by breaking off from the site of thrombosis in the limbs, and then traveling in the bloodstream to the lungs to block a vessel there and cause difficulties in breathing. (news-medical.net)
  • Then we found that in the absence of these crosslinks, clots that form in the vena cava (central vein) break off much more easily and generate more emboli in the lungs. (news-medical.net)
  • We know that patients with severe COVID-19 have a really high risk of thrombosis, with a particularly high risk of clots in the lungs. (news-medical.net)
  • These parasites cause irreversible permanent damage to the blood vessels in the heart and lungs," explains Ernie Ward , DVM, CVFT. (dogster.com)
  • It usually happens when a blood clot breaks loose and travels through the bloodstream to the lungs. (weitzlux.com)
  • Blood clots can travel to the lungs, heart, and brain. (weitzlux.com)
  • Permanent damage to the lungs - Lung tissue can be irreversibly damaged when blood cannot reach your lungs because of a blood clot. (weitzlux.com)
  • The primary task of this filter is to break blood clots and prevent them from traveling to the heart and lungs. (uwec.edu)
  • PE occurs when (part of) a blood clot detaches from the deep vein and ends up in the lung blood vessels, blocking the blood supply of the lungs. (cochrane.org)
  • however, in addition to respiratory problems, people with COVID‐19 can also experience problems with their blood vessels, leading to blood clots forming in the veins and lungs. (cochrane.org)
  • Lisa was an active 27 year old woman when her life was interrupted by blood clots in both her left leg and her lungs that she found out were related to May Thurner's Syndrome. (stoptheclot.org)
  • A filter was placed in my inferior vena cava to prevent any more clots from entering my lungs. (stoptheclot.org)
  • Three months is usually the best time to remove filters that are placed to prevent blood clots from entering the lungs. (stoptheclot.org)
  • If you stop taking this medication early, you have a higher risk of forming a serious blood clot (such as a stroke , blood clot in the legs / lungs ). (webmd.com)
  • IVC filters are designed to filter or "catch" blood clots (called "thrombi") emanating in the legs before they reach the lungs. (lieffcabraser.com)
  • No. The usual therapy for a patient at risk for blood clots traveling from the legs to the lungs is anticoagulation drug therapy, such as heparin or Coumadin. (lieffcabraser.com)
  • Again, retrievable IVC filters are intended to provide temporary protection from blood clots in the lungs. (lieffcabraser.com)
  • A blood clot (thrombus) in a deep vein, usually in the legs, is dislodged and travels to the lungs where it blocks one or more vessels. (escardio.org)
  • The aim is to get to the diagnosis as reliably and quickly as possible, in order to start lifesaving therapy and prevent other clots from reaching the lungs," said Professor Guy Meyer, Co‐Chairperson of the guidelines Task Force and respiratory medicine physician, Hôpital Européen Georges-Pompidou, Paris, France. (escardio.org)
  • This can prevent blood from flowing to important organs such as the lungs, leading to serious health problems. (medlineplus.gov)
Platelets13
  • Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, white blood cells, plasma, platelets, and other clotting factors. (wikipedia.org)
  • Platelets are involved in blood clotting, preventing the body from bleeding. (wikipedia.org)
  • Bleeding problems and/or low number of platelets in your blood. (medicines.org.uk)
  • A protective clot begins to form from two substances: platelets and fibrin. (weitzlux.com)
  • Platelets are a type of blood cell. (weitzlux.com)
  • Laboratory tests (e.g., blood counts including platelets, stool occult blood) should be done periodically while using this medication to minimize side effects. (patientassistance.com)
  • Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. (scitechdaily.com)
  • The subcommittee has reviewed reports of rare cases of blood clots with low platelets following vaccination with the AstraZeneca COVID-19 vaccine. (who.int)
  • Based on current information, a causal relationship between the vaccine and the occurrence of blood clots with low platelets is considered plausible but is not confirmed. (who.int)
  • We were interested in finding out what happens in the blood clot that forms in the heart in the case of a heart attack, so we studied microRNAs in blood platelets. (lu.se)
  • Blood platelets are cells which lack a nucleus and which do not produce their own proteins", says Olof Gidlöf. (lu.se)
  • Our hypothesis was that the blood platelets which were activated in conjunction with the heart attack had emptied their content of microRNAs and that that was the explanation behind the lower values in the heart attack patients", explains Olof Gidlöf. (lu.se)
  • This is why we also investigated what happens in blood platelets activated in a test tube in the lab. (lu.se)
Serious blood clots3
  • Whether you have had an inpatient or outpatient procedure, your health care provider should be on the lookout for potentially serious blood clots. (weitzlux.com)
  • I was in utter shock, since I didn't know anybody in my family with a history of blood clots, and I certainly didn't know how serious blood clots were until I had one. (stoptheclot.org)
  • Decreasing high homocysteine levels may help prevent serious blood clots, abnormal bone formation, brittle bones (osteoporosis), and eye problems (such as dislocated eye lens, nearsightedness). (medscape.com)
Vessels16
  • Veins are blood vessels that have valves to make sure the blood flows against the direction of gravity. (news-medical.net)
  • Mocco suspects the virus is damaging the cells that line blood vessels, allowing blood to come in contact with substances in the body that cause clotting. (kios.org)
  • A thin, flexible tube (catheter) is inserted through the radial artery in the hand and into the heart and its blood vessels. (medicinenet.com)
  • Advancement in technology has made transradial catheterization possible with thinner catheters that can go through smaller blood vessels. (medicinenet.com)
  • This process may be triggered by an injury or it can sometimes occur inside blood vessels that don't have an obvious injury," according to the Mayo Clinic . (weitzlux.com)
  • Depending on the patient's symptoms, condition and medical history, medication will be administered to dilate the blood vessels, lower the blood pressure, prevent thrombosis and slow the heart beat or, if necessary, accelerate it. (biotronik.com)
  • According to a recent review, garlic consumption can help to loosen blood vessels and improve blood flow. (ganeshaspeaks.com)
  • Hypertension, or high blood pressure, puts strain on the blood vessels throughout the body, including the kidneys. (proprofs.com)
  • Over time, this can damage the blood vessels in the kidneys and impair their ability to filter waste and excess fluid from the body. (proprofs.com)
  • Plasmodium parasites, which infect red blood cells, bind to and damage the small blood vessels in the brain resulting in seizures or coma. (gla.ac.uk)
  • During cerebral malaria, fluid leaks out from blood vessels in the brain. (gla.ac.uk)
  • In brain samples from 16 children who died from cerebral malaria they observed that the histones were stuck to brain vessels in proximity to concentrations of the parasite and were stuck to blood vessels precisely in the areas where vessels were leaky. (gla.ac.uk)
  • Anticoagulant drugs (blood thinners) help the body dissolve clots and reopen the blocked vessels. (escardio.org)
  • While this is a normal part of the healing process, sometimes they form without warning and can block blood vessels. (medlineplus.gov)
  • An angiosarcoma (AS) is an uncommon malignant neoplasm characterized by rapidly proliferating, extensively infiltrating anaplastic cells derived from blood vessels and lining irregular blood-filled spaces. (medscape.com)
  • It's important to determine whether the mutation is specific to one type of vascular cell, for example, endothelial cells that line the lumen of vessels and regulate exchanges between tissue and blood and help prevent clotting, or vascular smooth muscle cells in the vessel wall that regulate the vessel diameter and adjust the blood flow like a faucet would. (medscape.com)
Life-Threatening Blood Clots1
  • Scientists have new evidence that overactive neutrophils--a common type of circulating immune cell--may drive the life-threatening blood clots and inflammation that occur in some patients with COVID-19. (news-medical.net)
Anticoagulants7
  • Hallstrom is the lead author of a new study published in JAMA Surgery that found few patients developed a blood clot after surgery, and those patients on aspirin fared just as well as those on anticoagulants. (sciencedaily.com)
  • Over the past decade, surgeons have turned away from powerful anticoagulants and toward aspirin used in addition to nondrug improvements such as compression devices for thwarting clots. (sciencedaily.com)
  • Patients can get it over the counter for pennies, while the other anticoagulants require monitoring, injections, frequent dose adjustments and are extremely expensive. (sciencedaily.com)
  • Caution should be used if surgery or dental work is planned and in patients taking medications to prevent blood clotting (anticoagulants) such as warfarin /Coumadin. (rxlist.com)
  • The initial treatment includes drugs such as anticoagulants to prevent the formation of further new blood clots. (cochrane.org)
  • Anticoagulants such as rivaroxaban and apixaban act by inhibiting the blood elements involved in the formation of blood clots. (cochrane.org)
  • Anticoagulants are used to treat the acute episode and prevent recurrence but raise the risk of bleeding. (escardio.org)
Occurs when a blood clot forms1
Venous9
  • Healthcare-associated venous thromboembolism (blood clots) is a significant, deadly, costly, and growing public health problem. (cdc.gov)
  • Today I would like to talk about the risks associated with venous thromboembolism (VTE) for long-distance travelers and discuss how you can counsel patients on reducing their risks. (medscape.com)
  • Central venous access is often necessary for patients for a variety of reasons, including ongoing hemodynamic monitoring, direct intravenous access, or long-term intravenous therapy. (globenewswire.com)
  • Patients and healthcare professionals have become more aware of venous diseases due to a greater emphasis on early diagnosis and treatment. (globenewswire.com)
  • As a result, venous procedure devices have become more widely adopted and patient access to treatment options has increased. (globenewswire.com)
  • Dr. Matz continues to bring innovative, high-quality venous insufficiency treatments to Canada, and extensively trains our medical staff and partnering physicians through our on on-going training programs to ensure high-quality patient care. (whatclinic.com)
  • Under certain circumstances, this can lead to venous insufficiency, which is characterized by improperly functioning vein valves that interfere with venous return and cause the blood to pool in the veins. (sigvaris.com)
  • Total shoulder arthroplasty (TSA) should not be performed in patients with glenohumeral osteoarthritis (GHOA) who have an irreparable rotator cuff tear, and physicians should use perioperative mechanical or chemical venous thromboembolism prophylaxis for patients who have undergone shoulder arthroplasty. (hcplive.com)
  • International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism (VTE) in patients with cancer were issued in early 2013. (medscape.com)
Medications9
  • Medications to prevent clots are recommended only when the potential benefits outweigh the risks. (medscape.com)
  • Glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) are a class of injectable medications that lower blood glucose and can also cause a reduction in weight. (eurekalert.org)
  • Therefore, newer, stronger antiplatelet medications (a form of blood thinner) should be considered. (eurekalert.org)
  • Since all antiplatelet medications increase the risk of bleeding, it is important to balance the risk for each patient of increased bleeding versus the benefit of reducing the tendency of the blood to clot," said Arnold. (eurekalert.org)
  • Patients should take all prescribed medications correctly. (whatclinic.com)
  • This risk is increased when you use other "blood thinning" medications (e.g., aspirin, clopidogrel, warfarin), NSAIDs (e.g., ibuprofen, naproxen), or when certain medication delivery devices (indwelling epidural catheters) are used. (patientassistance.com)
  • There were none of the dietary restrictions that other blood-thinning medications required. (inquisitr.com)
  • IVC filters, however, are inserted in patients when medications to dissolve clots cannot be used or are ineffective. (lieffcabraser.com)
  • Exercises to increase blood flow and blood-thinning medications also can help prevent blood clots. (hcplive.com)
Dissolve1
  • If the heart attack was caused by a blood clot (thrombus), the physician may try to dissolve the clot with medication. (biotronik.com)
Thinners to prevent2
Prevention11
  • Proven ways to prevent blood clots from occurring during or after a healthcare encounter exist, but not all hospitals and healthcare facilities have put these prevention strategies into practice or use them routinely. (cdc.gov)
  • I am Dr. Lisa Richardson, Director for the Division of Blood Disorders at the Centers for Disease Control and Prevention (CDC). (medscape.com)
  • I encourage all clinicians to become familiar with the prevention measures appropriate for each patient, because prevention is not a one-size-fits-all approach. (medscape.com)
  • Based on the experience of 41,537 Michigan patients undergoing knee replacement, the study may further the debate about the routine use of aspirin for clot prevention. (sciencedaily.com)
  • They also wanted to learn more about the risk factors, consequences, and prevention of blood clots, the researchers reported in PLOS ONE . (pcori.org)
  • The study also asked what sort of training could educate bedside nurses about the importance of VTE prevention and how they could best pass this information on to patients. (pcori.org)
  • The Preeclampsia Foundation announced today that the Centers for Disease Control and Prevention (CDC) awarded new funding for its MoMMA's Voices program, a national coalition of patient advocacy. (preeclampsia.org)
  • Do not use this medication for prevention of blood clots (e.g., after surgery) if you have had a heart valve replacement, especially if you are pregnant. (patientassistance.com)
  • According to JNC 7 (The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure), the normal range for blood pressure is considered to be 120/80. (proprofs.com)
  • Most stroke victims are also prescribed a blood thinner as a prevention as well. (inquisitr.com)
  • Blood lead levels measured in previous NHANES cycles have been the cornerstone of lead exposure surveillance in the U.S. The data have been used to document the burden and dramatic decline of elevated blood lead levels, to promote the reduction of lead use, and to help to redefine national lead poisoning prevention guidelines, standards, and abatement activities. (cdc.gov)
Researchers19
  • Researchers at Cold Spring Harbor Laboratory (CSHL), University of Utah Health, PEEL Therapeutics and Weill Cornell Medicine collaborated to investigate NETs suspected role in COVID-19, collecting blood samples from 33 hospitalized patients, as well as autopsy tissue. (news-medical.net)
  • In the laboratory, neutrophils from patients with COVID-19 churned out exceptionally high levels of NETs, and the researchers found healthy neutrophils behaved the same way when they were exposed to plasma from patients with the illness. (news-medical.net)
  • Patients, family members, and members of national organizations focused on this medical problem told the researchers that they wanted to know the signs and symptoms of clots. (pcori.org)
  • Randy Fenninger, JD, the chief executive of National Blood Clot Alliance and a survivor of blood clots, who appears in the video, says that the researchers really listened to the patients' ideas about the educational materials. (pcori.org)
  • People who live to 100 years have lower measures of creatinine, glucose and uric acid in their blood compared to those with a comparatively shorter lifespan, researchers say. (medicaldaily.com)
  • People with low levels of iron in their blood have a greater chance of dangerous blood clots, researchers said Wednesday. (medicaldaily.com)
  • Scientists have pinpointed 16 new genetic differences in people who developed severe COVID-19 in a large study that could help researchers develop treatments for very sick patients. (cbc.ca)
  • For example, the researchers found changes in key genes that regulate the level of factor VIII, a protein involved in forming blood clots. (cbc.ca)
  • In a recent study of people with T2D and a diagnosis of heart disease, researchers found that patients taking SGLT2 inhibitors were significantly less likely to die of cardiovascular disease. (eurekalert.org)
  • The finding brings researchers closer to finding the exact cause of inflammation and clotting in severe COVID-19 patients. (scitechdaily.com)
  • In 2005, researchers discovered a mutation in the Janus Tyrosine Kinase 2 gene (JAK2 (V617F)), which plays a pivotal role in the regulation of blood cell production (Levine et al. (cdc.gov)
  • Blood clots are a major health problem, but researchers are making progress in understanding and treating them. (medlineplus.gov)
  • Researchers are also studying how blood clots form in the body during septic shock and investigating new drugs to prevent them. (medlineplus.gov)
  • Researchers are developing new tools to predict who is at greater risk of blood clots. (medlineplus.gov)
  • NIH-funded researchers are making significant progress in understanding and treating blood clots. (medlineplus.gov)
  • The researchers investigated both blood and blood clots from patients with a form of serious heart attack caused by a constriction, a so-called plaque, coming loose in one of the major coronary arteries in the heart. (lu.se)
  • What the researchers were able to observe in their study was that nine different microRNAs were clearly distinguishable between patients who had suffered a heart attack and healthy individuals. (lu.se)
  • Researchers have identified a genetic mutation in patients with an arteriovenous malformation (AVM) of the brain, a leading cause of hemorrhagic stroke in young adults and children. (medscape.com)
  • In total, the researchers detected somatic activating KRAS mutations in tissue samples from 45 of 72 patients and in none of the 21 paired blood samples. (medscape.com)
Heparin5
  • Some doctors choose powerful anti-clotting drugs like heparin (Lovenox) and rivaroxaban (Xarelto), but it hasn't been clear whether these expensive prescription drugs work any better than cheap, readily available aspirin. (sciencedaily.com)
  • The critical care specialists who make up the American College of Chest Physicians favor heparin to reduce the risk of blood clots, while the American Academy of Orthopaedic Surgeons guidelines state that no one drug is better than another for preventing clots. (sciencedaily.com)
  • My left leg became twice the size of my right leg and I was on a heparin drip and warfarin to treat the blood clots, and pain medication to relieve the pain. (stoptheclot.org)
  • I took my ability to run for granted before my clots, and I am no longer on warfarin or low molecular weight heparin! (stoptheclot.org)
  • However, hemodialysis treatment may also be done with regional anticoagulation of the dialysis circuit (using heparin or trisodium citrate) or with saline flush, in which 50 to 100 mL of saline every 15 to 30 minutes clears the dialysis circuit of any blood clots. (msdmanuals.com)
20221
  • We retrospectively studied patients with fever, chills, antibiotic use for more than 3 days, suspected bloodstream infection, and admission to the emergency department of Ruijin Hospital from January 2020 to June 2022. (cdc.gov)
Thrombosis3
  • Pediatric thrombosis is the term for a blood clot in a child. (medicalnewstoday.com)
  • It will be important to investigate NETs role in clot formation (thrombosis) not only in light of the COVID-19 pandemic, but also to understand their broader role in disease. (news-medical.net)
  • Symptoms including shortness of breath and chest pain resemble other diseases so the diagnosis is often missed, or the severity of the situation is underestimated, and many patients die before getting appropriate therapy," said Professor Stavros Konstantinides, Chairperson of the guidelines Task Force and medical director, Centre for Thrombosis and Haemostasis, Johannes Gutenberg University Mainz, Germany. (escardio.org)
Risk for a blood clot2
Symptoms of a blood clot2
  • What are the signs and symptoms of a blood clot? (cdc.gov)
  • The Agency for Healthcare Research and Quality (AHRQ) notes that the symptoms of a blood clot in a person's leg include swelling, flushed skin, pain in the leg, and the leg feeling warm to the touch. (medicalnewstoday.com)
Knee replace2
  • The U-M study involved patients undergoing knee replacement surgery at any of the 29 Michigan hospitals in the surgical quality group. (sciencedaily.com)
  • Rivaroxaban is used to prevent blood clots from forming due to a certain irregular heartbeat ( atrial fibrillation ) or after hip or knee replacement surgery . (webmd.com)
20232
  • Cite this: New 'C Word': Cure Should Be the Goal for Patients With Lung Cancer - Medscape - Sep 19, 2023. (medscape.com)
  • April 4, 2023 - Medication is the first to reduce bone-weakening process in patients with fibrous dysplasia. (nih.gov)
Thinner5
  • On day three, a platlet level will also be measured as low platlets counts can occur as a side effect of Lovenox (blood thinner). (wheelessonline.com)
  • Hospitalized patients are at elevated risk of VTE, but according to several studies, these patients miss about 12 percent of their blood-thinner doses, most often because they refuse to take them when offered. (pcori.org)
  • Aspirin, which is a blood thinner, may be appropriate for many people with CAD, but may not work as effectively in people with T2D and CAD. (eurekalert.org)
  • This medication is a "blood thinner" which helps prevent formation of blood clots. (patientassistance.com)
  • A lot of patients are temporarily prescribed Xarelto or another blood thinner after hip and knee surgery to prevent clots from forming in legs. (inquisitr.com)
Preventable3
  • As many as 70% of healthcare-associated blood clots are preventable. (cdc.gov)
  • It is important to increase patients' awareness, because blood clots may be preventable. (medscape.com)
  • These deaths are largely preventable with modern blood thinners. (pcori.org)
Inflammation1
  • The results suggest that people with severe COVID have genes that predispose them to one of two problems: failure to limit the ability of the virus to make copies of itself, or excessive inflammation and blood clotting. (cbc.ca)
Aspirin7
  • When it comes to preventing blood clots after a knee replacement, good old aspirin may be just as effective as newer, more expensive drugs, such as rivaroxaban (Xarelto), according to a orthopedics study. (sciencedaily.com)
  • During the two-year study period from 2013 to 2015, aspirin use rose from 10 percent to 50 percent among the patients cared for by orthopaedic surgeons in the Michigan Arthroplasty Registry Collaborative Quality Initiative, a statewide effort to give patients the best possible recovery and outcomes after hip and knee replacements. (sciencedaily.com)
  • The new U-M study suggests patients may be adequately protected if they take aspirin alone from day one. (sciencedaily.com)
  • Over three months, just 1.16 percent of aspirin patients developed a serious blood clot. (sciencedaily.com)
  • Garlic can decrease normal blood clotting in a manner similar to aspirin. (rxlist.com)
  • Aspirin can prevent the formation of blood clots. (preeclampsia.org)
  • This can make aspirin useful in treating or preventing some conditions like heart attacks and st. (preeclampsia.org)
COVID27
  • High levels of the sticky, pathogen-trapping webs produced by the cells were associated with the most severe cases of COVID-19 in a study reported online in the journal Blood . (news-medical.net)
  • When too many of these NETs accumulate during a persistent infection, they can lead to acute respiratory distress syndrome, which leads many patients with COVID-19 to require intensive care. (news-medical.net)
  • They found that biomarkers of NET formation were more abundant in patients who required ventilation, and highest in the three study participants who eventually died from COVID-19. (news-medical.net)
  • We also know that clotting is a major cause of death in people with end-stage cancer, so what we are learning in COVID-19 may help us understand basic properties in cancer and other diseases. (news-medical.net)
  • Although further studies will be required, the NET-inhibitory protein may block exaggerated NET formation in COVID-19 patients,' says Christian Con Yost, whose laboratory at University of Utah Health discovered nNIF in 2016. (news-medical.net)
  • Why is research into blood clots of particular importance currently in light of the ongoing COVID-19 pandemic? (news-medical.net)
  • A medical worker transports a patient at New York's Mount Sinai Hospital, where doctors noticed that some young COVID-19 patients without other risk factors had strokes. (kios.org)
  • When COVID-19 patients began flooding emergency departments at New York hospitals in March, doctors saw some unusual cases of stroke. (kios.org)
  • COVID-19 seems to produce blood clots - a lot of them. (kios.org)
  • Patients who are in the intensive care unit for other causes are at risk of having clots, but nothing like the levels were seeing with COVID-19," says Dr. Craig Coopersmith , a professor of surgery and interim director of the critical care center at Emory University School of Medicine in Atlanta. (kios.org)
  • But he is seeing abnormal clotting in a "significant minority" of ICU patients with COVID-19. (kios.org)
  • Perhaps most surprising, he says, are the COVID-19 patients on dialysis machines, which remove waste products from the blood of people whose kidneys are failing. (kios.org)
  • Even so, blood thinners are able to reduce clotting in most patients with COVID-19. (kios.org)
  • We have literally five different teams in the hospital specifically and only looking at blood clotting, just because of COVID," he says. (kios.org)
  • It's still not clear precisely how COVID-19 is causing blood clots. (kios.org)
  • And some hints about how COVID-19 affects clotting are coming from lab tests of patients, says Dr. Tiffany Osborn , a professor of surgery and emergency medicine at Washington University in St. Louis. (kios.org)
  • And there's growing evidence that blood clots associated with COVID-19 are causing problems through the body. (kios.org)
  • A transmission electron microscope image shows SARS-CoV-2, the virus that causes COVID-19, isolated from a patient in the U.S., with virus particles seen emerging from the surface of cells cultured in the lab. (cbc.ca)
  • The genetic analysis of nearly 56,000 samples from people in Britain showed differences in 23 genes in COVID-19 patients who became critically ill, when compared with the DNA of other groups included in the study, including 16 differences that had not been previously identified. (cbc.ca)
  • Blood clotting is one of the main reasons why patients with COVID develop a shortage of oxygen. (cbc.ca)
  • The drug was shown last week to cut the risk of death and hospitalization in COVID-19 patients by 13 per cent in a trial. (cbc.ca)
  • Scientists have identified how and why some COVID-19 patients can develop life-threatening clots, which could lead to targeted therapies that prevent this from happening. (scitechdaily.com)
  • For this reason, they are also used to prevent blood clots from forming in people who are considered to be at risk, such as people with COVID-19. (cochrane.org)
  • Rare adverse events following immunizations should be assessed against the risk of deaths from COVID-19 disease and the potential of the vaccines to prevent infections and reduce deaths. (who.int)
  • I'd like to welcome you to today's COCA Call, Evaluating and Supporting Patients with Long COVID in Returning to Work. (cdc.gov)
  • Describe how to assess current functional abilities and establish functional goals for patients with Long COVID. (cdc.gov)
  • And outline how to develop a usable return to work plan for patients with Long COVID who have been out of work. (cdc.gov)
Occur7
  • Although there are many reasons a person might develop a blood clot, about half of them are directly related to a recent hospitalization or surgery and most of these do not occur until after discharge. (cdc.gov)
  • The AHRQ says that blood clots are more likely to occur if a person is unable to move around a lot. (medicalnewstoday.com)
  • Pain may occur in the part of the leg where the blood clot has developed. (medicalnewstoday.com)
  • Blood clots can occur when you get hurt, such as if you fall. (weitzlux.com)
  • Most hip fractures occur in elderly patients whose bones have become weakened by osteoporosis . (orthoinfo.org)
  • Most of these fractures occur in patients 65 years of age or older who are injured in household or community falls. (orthoinfo.org)
  • Epidural or spinal hematomas may occur in patients who are anticoagulated with low molecular weight heparins (LMWH), heparinoids, or fondaparinux sodium and are receiving neuraxial anesthesia or undergoing spinal puncture. (rxlist.com)
Warfarin2
  • Should we be treating fewer patients with warfarin (Coumadin)? (clotcare.com)
  • The risk of bleeding may be higher if you have a deformed spine, or have had spinal procedures/surgery before (such as epidural catheter placement, difficult epidural /spinal puncture), or are taking other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel , " blood thinners " such as warfarin / enoxaparin , nonsteroidal anti-inflammatory drugs- NSAIDs such as ibuprofen ). (webmd.com)
Potentially6
  • Avoiding potentially fatal blood clots may often be as straightforward as better educating hospitalized patients about the importance of preventive treatment. (pcori.org)
  • It is potentially possible in future that we will be able to make predictions about patients based on their genome at the point of presenting [for] critical care,' Kenneth Baillie, consultant in critical care medicine at the University of Edinburgh and one of the study authors, told reporters. (cbc.ca)
  • So that's potentially targetable to prevent those clots from forming,' Baillie said. (cbc.ca)
  • Surgeons should routinely take preventive steps to reduce the risk of potentially catastrophic complications caused by blood clots during and immediately after surgery. (hcplive.com)
  • Modified heparins have been shown to be safe in patients with malaria in whom they had other potentially beneficial effects. (gla.ac.uk)
  • Dr Christopher Moxon, of the University of Glasgow's Wellcome Centre for Integrative Parasitology, who led the study, said: "Our findings, that identify a potential treatment target and potentially deployable treatment for cerebral malaria, may be an important step toward improving clinical outcomes for patients with this devastating disease. (gla.ac.uk)
Risks5
  • In their PCORI-funded project, Elliott Haut, MD, PhD, of Johns Hopkins University and his research team looked at the effects of educating patients and nurses about the risks of VTE and the benefits of preventive treatment. (pcori.org)
  • Because each unit of blood given carries risks, a trigger level lower than that, at 70 to 80g/L, is now usually used, as it has been shown to have better patient outcomes. (wikipedia.org)
  • Consider these risks when scheduling patients for spinal procedures. (rxlist.com)
  • Consider the benefit and risks before neuraxial intervention in patients anticoagulated or to be anticoagulated for thromboprophylaxis. (rxlist.com)
  • This new system will provide treatment that will not rely on blood thinners or aggressive thrombolytic therapy which have their own inherent risks and for which every patient is not a candidate. (woodlandheights.net)
Hormonal1
  • I was also taking hormonal birth control pills, which added to my risk for blood clots, so I stopped them right after I was diagnosed. (stoptheclot.org)
Surgery10
  • A recent Canadian study looked at the issue, but the analysis had a caveat: Each of the more than 3,400 clinical trial patients received rivaroxaban the first five days after surgery. (sciencedaily.com)
  • How Should We Prevent Blood Clots Following Arthroscopic Knee Surgery? (clotcare.com)
  • Studies have found a greater reduction in the 5-year risk of death, heart attack or recurrent angina/chest pain when patients with T2D and CAD undergo coronary artery bypass graft (CABG) surgery to widen a narrowed blood vessel instead of treating the narrowing with angioplasty and stenting. (eurekalert.org)
  • Patients are able to walk around soon after treatment, with reduced pain, faster recovery and similar cosmetic results in comparison to conventional vein surgery. (sigvaris.com)
  • This surgery has allowed me to live a normal life and prevented me from dealing with lifelong severe leg swelling and pain. (stoptheclot.org)
  • Rivaroxaban may be used in children to prevent blood clots from forming after a certain heart surgery (Fontan procedure). (webmd.com)
  • If you are taking this medication to prevent blood clots due to other conditions (such as after knee or hip replacement surgery , during a hospital stay and after discharge, after Fontan procedure), the dose is usually taken once a day. (webmd.com)
  • For example, IVC filters have been increasingly used following gastric bypass or bariatic surgery and other types of major surgery when a patient is temporarily at risk for DVT and traditional anticoagulation may cause serious bleeding. (lieffcabraser.com)
  • If the patient is in shock and about to collapse, the clot must be removed immediately, and this can be achieved using thrombolytic drugs (clot busters), catheters, or surgery. (escardio.org)
  • For the study, he and his team analyzed tissue from 39 adult patients with AVMs of the brain who had undergone surgery in Toronto. (medscape.com)
Inferior vena1
  • IVC filters are small, spider-like medical devices that are inserted into the inferior vena cava, which is the main blood vessel that returns blood from the lower half of the body to the heart. (lieffcabraser.com)
Vessel8
  • A combination of factors can contribute to clot formation, including prolonged immobility, endothelial cell (cells that line the blood vessel) dysfunction, and a procoagulant state (heightened blood clotting activity) due to genetic or environmental factors. (news-medical.net)
  • The catheters used in the earlier days were larger and needed a large blood vessel to go through. (medicinenet.com)
  • Usually, "blood clots start as a response to injury of a blood vessel. (weitzlux.com)
  • Even a slight injury to a blood vessel can activate your body's response. (weitzlux.com)
  • When an injury occurs to a blood vessel, the blood stays right there initially. (weitzlux.com)
  • They plug up the cut or hole in the blood vessel. (weitzlux.com)
  • In this procedure, a new route for the blood is provided by implanting a segment of a healthy vessel from another part of the patient´s body. (biotronik.com)
  • When this happens, a 'wound' forms in the blood vessel wall, which must be repaired. (lu.se)
Abnormal1
  • My doctor called me the next morning to say that my blood work was abnormal, and ordered an ultrasound on my leg. (stoptheclot.org)
Antiplatelet1
  • Your doctor may direct you to take a different "blood thinning" or antiplatelet medication to reduce your risk. (webmd.com)
Protein3
  • Another possible test is the D-dimer blood test, which checks for D-dimers - protein fragments that the body produces when a clot breaks up . (medicalnewstoday.com)
  • Also, I wanted to know what, if anything, crosslinking of the building material of the clot (a protein called fibrin) by a transglutaminase enzyme called factor XIII had to do with this. (news-medical.net)
  • What role does the protein fibrin play in blood clots? (news-medical.net)
Clump2
Veins7
  • Usually, the clot formation starts around the valves in these veins. (news-medical.net)
  • Varicose veins, also known as varicosities, are thick and dark blue or purple veins that are seen in the lower limbs of patients. (whatclinic.com)
  • Varicose veins are treated by making patients wear compression stockings, by helping them to lose weight, by sclerotherapy, injecting a chemical into the vein to make it collapse, laser and radiofrequency assisted procedures, phlebectomy procedures, where veins are removed by making small cuts on the surface of the skin and by surgical procedures involving tying or stripping of the varicose veins. (whatclinic.com)
  • Enquire for a fast quote ★ Choose from 5 Varicose Veins Treatment Clinics in New Brunswick, Canada with 3 verified patient reviews. (whatclinic.com)
  • The sclerosant leads to occlusion of the vein wall, causing blood to be transported to other, healthier veins. (sigvaris.com)
  • Blood supply is redirected to healthier veins and the sealed vein is eventually reabsorbed by local tissue. (sigvaris.com)
  • As a result, blood clots can form more easily and block blood flow through arteries and veins. (cdc.gov)
Patient's2
  • In hemodialysis, a patient's blood is pumped into a dialyzer containing 2 fluid compartments configured as bundles of hollow fiber capillary tubes or as parallel, sandwiched sheets of semipermeable membranes. (msdmanuals.com)
  • Anticoagulant therapy prevents further clot deposition and allows the patient's natural fibrinolytic mechanisms to lyse the existing clot. (medscape.com)
Compression stockings4
  • For patients who have risk factors, compression stockings may be prescribed. (medscape.com)
  • They should wear compression stockings to prevent blood clots. (whatclinic.com)
  • Patients may also receive compression stockings and clinical care (e.g. physical exercise, skin hydration, and physical therapy). (cochrane.org)
  • In addition, patients are usually advised to wear compression stockings or bandages for a certain duration. (sigvaris.com)
Strokes1
  • If you are taking this drug to prevent strokes and blood clots that may form due to an irregular heartbeat, the dose is usually taken once a day with the evening meal. (webmd.com)
Lawsuits2
  • Many patients who have suffered these side-effects have now become the plaintiffs in two class-action lawsuits filed in federal courts in Louisiana and Pennsylvania. (inquisitr.com)
  • The lawsuits that have been filed by patients claim that these warnings were not given to the public as the medication was being advertised on TV, in magazines, and in pamphlets. (inquisitr.com)
Vaccination1
  • New research highlights the need for heightened awareness and early testing for patients with signs of clotting disorder following vaccination. (scitechdaily.com)
Help prevent5
  • Move your arms and legs to help prevent blood clots from forming. (cdc.gov)
  • This will also help prevent blood clots. (wheelessonline.com)
  • Treating the fracture and getting the patient out of bed as soon as possible will help prevent medical complications such as bed sores, blood clots, and pneumonia. (orthoinfo.org)
  • Blood thinners help prevent clots from forming and growing larger. (medlineplus.gov)
  • If future research shows that it's safe and effective, MPI 8 could one day help prevent blood clots and reduce the risk of bleeding in humans. (medlineplus.gov)
Stroke9
  • It is used to reduce the risk of stroke in patients who have had or are at risk of stroke. (medlineplus.gov)
  • Her stroke was caused by a blood clot that was restricting blood flow to the right side of her brain. (kios.org)
  • Coopersmith isn't seeing the sort of stroke patients reported in New York: young people without risk factors. (kios.org)
  • Plavix , which is prescribed for patients at higher risk for heart attack or stroke, is an anti-platelet drug that works by helping to prevent blood from forming clots. (lawyersandsettlements.com)
  • There are now more options for controlling glucose in people with T2D, and each patient should be evaluated for their personal risk of cardiovascular disease, stroke and kidney disease. (eurekalert.org)
  • Xarelto is prescribed for patients with cardiovascular issues, most often those with circulation problems that could lead to blood clots and stroke. (inquisitr.com)
  • Stroke caused by intracerebral hemorrhage is defined as rapidly developing clinical signs of neurological dysfunction attributable to a focal collection of blood within the brain parenchyma or ventricular system. (medscape.com)
  • The influence of both modifiable and unmodifiable risk factors are discussed, to permit estimation of risk for a first stroke for an individual patient. (medscape.com)
  • In older adults, hemorrhagic stroke s are often the result of high blood pressure. (medscape.com)
Drugs10
  • So it's routine for patients to take clot-preventing drugs for some time afterward. (sciencedaily.com)
  • His research interests include targeted therapies for lung cancer, multimodality therapy, the development of new anticancer drugs, and symptom management with a focus on preventing emesis. (medscape.com)
  • How will your research help to identify new drugs that can target blood clots? (news-medical.net)
  • We are now in a unique position to develop new drugs that prevent clots or break them down that can replace currently used drugs, which are not always effective and can cause a heightened risk of bleeding. (news-medical.net)
  • An important difference is that the drugs can be switched abruptly in the laboratory, whereas in the patient, natural degradation processes lead to fluctuating antibiotic concentrations. (mpg.de)
  • But drugs that prevent clots or break them up can also cause uncontrolled bleeding, so patients on them have to be watched closely, Coopersmith says. (kios.org)
  • In addition, painkillers, sedatives and drugs that prevent nausea and vomiting may be administered. (biotronik.com)
  • Drugs inhibiting coagulation and preventing the formation of blood clots. (biotronik.com)
  • Antihypertensive drugs to lower blood pressure. (biotronik.com)
  • Together, these drugs work synergistically to control blood pressure and improve cardiovascular health. (proprofs.com)
Bloodstream5
  • In 2005, surveillance was expanded to include bloodstream infections, supported by the addition of an automated blood culture system and improved microbiology capacity ( 6 ). (cdc.gov)
  • The dialysate compartment is under negative pressure relative to the blood compartment and has a higher osmolality to prevent filtration of dialysate into the bloodstream and to remove the excess fluid from the patient. (msdmanuals.com)
  • Comparison of pathogen detection consistency between metagenomic next-generation sequencing and blood culture in patients with suspected bloodstream infection. (cdc.gov)
  • However, few studies have compared it with blood cultures in patients suffering from suspected bloodstream infections. (cdc.gov)
  • The purpose of this study was to compare the detection of pathogenic microorganisms by these two assays in patients with suspected bloodstream infection. (cdc.gov)
Fatal1
  • For 1 in 5 patients, cerebral malaria is fatal. (gla.ac.uk)
Iron deficiency1
  • In cases where patients have low levels of hemoglobin due to iron deficiency, but are cardiovascularly stable, parenteral iron is a preferred option based on both efficacy and safety. (wikipedia.org)
Diagnosis2
  • This report includes background on the state of molecular biomarkers for preeclampsia screening and diagnosis, identification of the needs and challenges facing the field, the proceedings and participants of the Biomarkers Consortium, and the resulting calls to action, broken out by stakeholders (research and academia, manufacturers and laboratories, clinical, regulatory, and patient organizations). (preeclampsia.org)
  • They also specify when and how (with which tools and tests) to follow patients, and which findings suggest chronic disease (CTEPH) requiring diagnosis and treatment in an expert centre. (escardio.org)
Intervention1
  • This will dictate whether blood thinners alone are sufficient or if clot busters, a catheter intervention, or surgical removal is necessary. (escardio.org)
Treatment21
  • Cangrelor, a treatment designed to prevent blood clots during heart artery-clearing angioplasty and stenting procedures, was rejected by the FDA in April 2014, following a February FDA advisory committee vote against approval. (citizen.org)
  • However, fewer than 50% of hospital patients receive appropriate preventive treatment. (cdc.gov)
  • Do I need preventive treatment to keep me from having a blood clot? (cdc.gov)
  • A study finds success in educating hospitalized patients about the importance of preventive treatment. (pcori.org)
  • I don't think I've ever seen a trial in lung cancer that looked at the ability of any given treatment to cure patients. (medscape.com)
  • The administration of a single unit of blood is the standard for hospitalized people who are not bleeding, with this treatment followed with re-assessment and consideration of symptoms and hemoglobin concentration. (wikipedia.org)
  • Over 20% of patients taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, suffer from the rebound, compared to less than the 2% chance seen in other treatment groups, a Harvard Medical School study revealed. (medicaldaily.com)
  • Recent research results from the Max Planck Institute for Evolutionary Biology in Plön suggest that rapid switching of antibiotics during the treatment of a patient could successfully counteract the evolution of resistance. (mpg.de)
  • Alone or together with the medicines pegylated liposomal doxorubicin or dexamethasone, for patients whose disease is worsening (progressive) after receiving at least one prior treatment and for whom blood stem cell transplantation was not successful or is unsuitable. (medicines.org.uk)
  • In combination with the medicines dexamethasone or dexamethasone together with thalidomide, for patients whose disease has not been previously treated and before receiving high-dose chemotherapy with blood stem cell transplantation (induction treatment). (medicines.org.uk)
  • Bortezomib is used for the treatment of mantle cell lymphoma (a type of cancer affecting the lymph nodes) in patients 18 years or older in combination with the medicines rituximab, cyclophosphamide, doxorubicin and prednisone, for patients whose disease has not been previously treated and for whom blood stem cell transplantation is unsuitable. (medicines.org.uk)
  • You will have to take regular blood tests before and during your treatment with Bortezomib, to check your blood cell counts regularly. (medicines.org.uk)
  • DALLAS, April 13, 2020 -- Type 2 diabetes (T2D) affects treatment options for patients who have both coronary artery disease (CAD) and T2D, according to a new American Heart Association Scientific Statement, published today in the Association's flagship journal Circulation . (eurekalert.org)
  • Preventing blood from forming clots is also an important goal of CAD treatment. (eurekalert.org)
  • Patients now have a safer, less invasive option for the treatment PE and DVT that can immediately relieve their symptoms and improve their vital signs and significantly affect their long-term quality of life for the better," said Dr. Fidone, who has performed dozens of these procedures. (woodlandheights.net)
  • The final treatment guidelines for patients included both operative and nonoperative options. (hcplive.com)
  • Injectable viscosupplementation is an option for the treatment of patients with GHOA. (hcplive.com)
  • The AAOS work group found a lack of quality prospective literature for recommending for or against treatment of patients who have GHOA with drug therapy, injectable corticosteroids, or arthroscopy for managing shoulder osteoarthritis (OA) or for treatment after shoulder replacement. (hcplive.com)
  • The major goal of treatment is to prevent thrombotic events. (cdc.gov)
  • This is accomplished by removal of blood through periodic phlebotomy and drug treatment to suppress red blood cell production by the bone marrow. (cdc.gov)
  • In May 2013, the American Society of Clinical Oncology (ASCO) released revised clinical practice guidelines on VTE prophylaxis and treatment in patients with cancer. (medscape.com)
Molecule2
  • Allicin, a molecule present in garlic, prevents LDL from oxidising (bad cholesterol). (ganeshaspeaks.com)
  • MPI 8 is a new compound that blocks a molecule in the blood called polyphosphate, which plays a role in blood clotting. (medlineplus.gov)
Outcomes2
  • The advisory caution to use blood transfusion only with more severe anemia is in part due to evidence that outcomes are worsened if larger amounts are given. (wikipedia.org)
  • AHRQ Projects funded by the Patient-Centered Outcomes Research Trust Fund. (ahrq.gov)
Anticoagulation2
  • However, anticoagulation only prevents new clots from forming and will not actively break down existing clots. (woodlandheights.net)
  • Patients with cancer have a high risk of recurrence, and indefinite anticoagulation is often necessary. (escardio.org)
Deaths1
  • Blood clots affect as many as 900,000 Americans each year leading to approximately 100,000 premature deaths. (cdc.gov)
Estrogen1
  • For example, they are studying how birth control methods that contain hormones such as estrogen affect clotting. (medlineplus.gov)
Formation5
  • Several therapeutic strategies for dismantling NETs or preventing their formation are currently under investigation. (news-medical.net)
  • Do you believe that with continued research into blood clot formation we will be able to reduce the number of people dying from them each year? (news-medical.net)
  • This is particularly important in patients who had a stent implantation because of the associated risk of blood clots formation. (biotronik.com)
  • Therapy with this medication may be continued for 7 to 14 days or until the risk of blood clot formation is limited. (patientassistance.com)
  • Post-procedure leg movement is important to prevent formation of blood clots. (sigvaris.com)
Rivaroxaban2
  • Rivaroxaban is an anticoagulant that works by blocking certain clotting proteins in your blood. (webmd.com)
  • For adults taking rivaroxaban to treat blood clots, the dose is usually taken twice a day for the first 3 weeks, and then once a day. (webmd.com)
Signs3
  • You should also let your patients know how to recognize the signs and symptoms of blood clots . (medscape.com)
  • Experienced health care providers should know the most common blood clot signs and risk factors. (weitzlux.com)
  • Monitor patients frequently for signs and symptoms of neurologic impairment. (rxlist.com)
Scientists2
  • Scientists now understand the mechanism that leads to platelet activation and clotting. (scitechdaily.com)
  • The work used a combination of lab and patient research, and scientists hope the findings will later be confirmed in clinical trials. (gla.ac.uk)
Form2
  • And if a dangerous clot does form, it can often be dissolved with a clot-busting drug. (kios.org)
  • Blood clots form when certain parts of your blood thicken, forming a semisolid mass. (weitzlux.com)
Affects1
  • This medication can cause serious bleeding if it affects your blood clotting proteins too much. (webmd.com)
Excessive1
Atrial Fibrillation1
  • We conducted a prospective multicenter study, including consecutive patients who underwent first PVI-only atrial fibrillation (AF) ablation. (bvsalud.org)