• The NOACs continued to demonstrate comparable efficacy and safety compared with VKAs in this group, 20, 21 with evidence indicating that the NOACs may also have preserved renal function compared with VKAs. (thrombosisadviser.com)
  • Since this is post-hoc analysis, the findings will need to be investigated further in prospective trials, but our analysis addresses an important issue since nearly two-thirds of these patients had renal impairment. (news-medical.net)
  • However, there appeared to be less post-operative bleeding in desirudin-treated patients with moderate renal impairment compared to enoxaparin-treated patients. (news-medical.net)
  • 60 ml/min) or renal impairment (CrCl≤60 ml/min). (news-medical.net)
  • Patients with renal impairment were more likely to be female (83 vs. 11%), older (70 vs. 60 years) and lighter weight (70 vs. 81 kg) than were patients with normal renal function. (news-medical.net)
  • Patients with renal impairment randomized to desirudin had a 56% reduction in major VTE and a 45% reduction in major bleeding compared with patients randomized to enoxaparin. (news-medical.net)
  • To determine the incidence of multiple myeloma in the Eastern District of Hong Kong Island, the degree of renal impairment at presentation, and its relationship with haematological and biochemical parameters and survival. (hkmj.org)
  • Demographic data, type and stage of multiple myeloma, degree of renal impairment, haematological and biochemical parameters, and survival data were analysed. (hkmj.org)
  • Renal impairment was more common in patients with light-chain multiple myeloma (P=0.081). (hkmj.org)
  • Renal impairment at resentation was common in patients with multiple myeloma and was associated with poor survival. (hkmj.org)
  • An earlier meta-analysis, in which Dr. Pandit was involved, found decreased risk of major bleeding with apixaban in mild to moderate renal impairment when compared with other anticoagulants (warfarin, aspirin, and Lovenox) as a group. (the-hospitalist.org)
  • This new study "exactly answers this question in a large patient population, providing sustained evidence that apixaban is safe and effective in mild to moderate renal impairment patients. (the-hospitalist.org)
  • CONCLUSION: Patients with pSS commonly present with renal impairment, mainly from renal tubular dysfunction. (jrheum.org)
  • Because Alex is a candidate for non-vitamin K antagonist oral anticoagulant (NOAC) treatment, his renal function was tested to check whether he would require dose reduction and, while his estimated glomerular filtration rate indicates mild renal impairment, it might not be considered severe enough to substantially worsen his prognosis or require special management. (thrombosisadviser.com)
  • Given this, why should you consider renal impairment at all? (thrombosisadviser.com)
  • Further information on the burden of renal impairment in AF can be found here . (thrombosisadviser.com)
  • We focused on the pharmacokinetics of daptomycin in children with renal impairment, which has not been evaluated. (simulations-plus.com)
  • Methods: A physiologically based pharmacokinetic (PBPK) model of daptomycin was established and validated to simulate its disposition in healthy populations and adults with renal impairment, along with a daptomycin exposure simulated in pediatric patients with renal impairment. (simulations-plus.com)
  • The C max and AUC of daptomycin did not differ significantly between children with mild-to-moderate renal impairment and healthy children. (simulations-plus.com)
  • The AUC increased by an average of 1.55-fold and 1.85-fold in severe renal impairment and end-stage renal disease, respectively. (simulations-plus.com)
  • We recommend monitoring creatine phosphokinase more than once a week when using daptomycin in children with renal impairment. (simulations-plus.com)
  • We have used reduced doses of Chinese herbs for estimation of urinary tract infections (UTIs) patients with stable impairment of renal function. (ajol.info)
  • Aims: To optimize the dosing regimen in patients with severe renal impairment based on population pharmacokinetic/pharmacodynamic (PPK/PD) analysis. (authorea.com)
  • Methods: The pharmacokinetics and safety of nemonoxacin was evaluated in a single-dose, open-label, nonrandomized, parallel-group study after single oral dose of 0.5 g nemonoxacin capsule in 10 patients with severe renal impairment and 10 healthy controls. (authorea.com)
  • Results: The data best fitted to a two-compartment model, from which the PPK parameters were estimated, including clearance (8.55 L/h), central compartment volume (80.8 L), and peripheral compartment volume (50.6 L). The accumulative urinary excretion was 23.4±6.5% in severe renal impairment patients and 66.1±16.8% in healthy controls. (authorea.com)
  • loading dose 0.5 g on Day 1 followed by 0.25 g q24h) were insufficient to cover the pathogens even if MIC ≤ 0.5 mg/L. Conclusion: An extended dosing interval (0.5 g q48h) may be appropriate for optimal efficacy of nemonoxacin in case of severe renal impairment. (authorea.com)
  • Sodium-glucose cotransporter 2 inhibitors in type 2 diabetes patients with renal function impairment slow the annual renal function decline, in a real clinical practice. (bvsalud.org)
  • We evaluated the annual eGFR slope in 85 type 2 diabetes mellitus patients with renal impairment, treated with SGLT2is ≥2 years. (bvsalud.org)
  • Lesions that characterize renal papillary necrosis come from an impairment of the blood supply and from subsequent ischemic necrosis that is diffuse. (wikipedia.org)
  • CROWNWeb¶ is the national ESRD patient registry and facilitates the collection of data and maintenance of information contains administrative and clinical data submitted by dialysis about ESRD patients on chronic dialysis or receiving a kidney facilities in the United States ( 6 ). (cdc.gov)
  • Renal-Disease/ESRDNetworkOrganizations ), which is directed by CMS, was with five variables: year, month, age group, age-group-by-year established to improve cost-effectiveness, ensure quality of care, encourage kidney transplant and home dialysis, and support patients returning to work. (cdc.gov)
  • Without dialysis consumables and supplies, the suffering of these patients is unbearable. (who.int)
  • Limited access to dialysis sessions and treatment put the lives of these vulnerable patients at higher risk, not to mention the suffering they go and their families through because of the lack of treatment," said Dr Abdulwahab Al-Nehmi, Noncommunicable Disease Officer at the WHO country office in Yemen. (who.int)
  • Between September 2019 and May 2020, up to 110 340 dialysis sessions were delivered to more than 4300 patients with chronic kidney failure. (who.int)
  • He is one of the patients receiving dialysis treatment at Al-Sadaqa hospital. (who.int)
  • Being a dialysis patient is very challenging. (who.int)
  • Much progress has been made in the management of kidney failure for patients with chronic kidney disease since dialysis was first introduced to the United Kingdom in the 1960's. (kidney.org.uk)
  • Advances in dialysis technology have meant that clinicians are able to offer dialysis older and frailer patients who may not have been offered dialysis previously. (kidney.org.uk)
  • It is important than, that patients and carers are informed about what may happen when dialysis does not have its intended benefits or if it is no longer possible for the patient to have dialysis because of personal choice or medical reasons. (kidney.org.uk)
  • Some patients will start dialysis but find that their health declines with a worse quality of life than they had expected. (kidney.org.uk)
  • Patients on dialysis and those with advanced chronic kidney disease will often have a high burden of physical and psychological symptoms similar to that seen in other chronic conditions including cancer. (kidney.org.uk)
  • Supportive care is defined as care that will improve health related quality of life for patients with kidney failure, at any age, and can be provided together with treatment intended to prolong life, such as dialysis and continuation of medical treatment to prevent transplant rejection. (kidney.org.uk)
  • Supportive care is suitable for kidney patients of any age, including those receiving dialysis, choosing conservative care (i.e. choosing not to dialyse), and those who have previously had a kidney transplant. (kidney.org.uk)
  • Supportive care does not mean that dialysis will be withdrawn immediately - If a patient is on dialysis then they will usually remain on dialysis while receiving supporting care. (kidney.org.uk)
  • The aim of supportive care is to ensure that the patient is able to have a reasonable quality of life while continuing to have active treatment such as dialysis. (kidney.org.uk)
  • 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) may have an adjunctive effect on chronic inflammation and nutrition status in renal dialysis patients. (nih.gov)
  • Therefore, we performed a systematic review of randomized controlled trials to assess the effect of statins on chronic inflammation and nutrition status in dialysis patients. (nih.gov)
  • The randomized controlled trials (RCTs) of statins versus placebo or no treatment for renal dialysis patients were searched from PubMed, EMbase and Cochran Central Register of Controlled Trials. (nih.gov)
  • P = 0.0007) of dialysis patients compared with that of the control group. (nih.gov)
  • Beginning in 2001 he required dialysis and underwent renal transplantation in 2004. (cdlib.org)
  • Will Implantable Bioartificial Kidneys Replace Dialysis in Patients with Renal Failure? (pharmaceutical-business-review.com)
  • Patients with end-stage renal disease (ESRD) currently have two treatment options, kidney transplant and dialysis. (pharmaceutical-business-review.com)
  • Powered by silicon nanotechnology, artificial kidneys seek to eliminate the torture faced by dialysis patients and may prove to be a boon to patients with acute renal failure. (pharmaceutical-business-review.com)
  • The medical sector meanwhile continues to introduce newer dialysis equipment in the global market to address the varied needs of patients. (pharmaceutical-business-review.com)
  • Home dialysis has remained a preferred option for patients with renal disease as it is more convenient and less expensive than hospital-based dialysis. (pharmaceutical-business-review.com)
  • Medical devices manufacturer Quanta has recently launched advanced haemodialysis equipment with an objective to improve the lives of patients requiring dialysis on a regular basis. (pharmaceutical-business-review.com)
  • This is an extremely flexible dialysis treatment that patients can take in the comfort of their homes. (pharmaceutical-business-review.com)
  • This dialysis equipment also incorporates advanced technology such as high-res screens with touchscreen functionalities and helps enhance patient outcomes. (pharmaceutical-business-review.com)
  • Manufacturers of dialysis equipment are developing fully automatic, portable, and advanced dialysis equipment to treat patients of all ages suffering from ESRD. (pharmaceutical-business-review.com)
  • Unlike traditional renal replacement machines, automated dialysis equipment facilitates the management of disease parameters digitally, thereby ensuring more accuracy and reducing costs of labour. (pharmaceutical-business-review.com)
  • With technology having proliferated every aspect of human lives, the innovation of wearable dialysis equipment is a blessing for countless dialysis patients who can now break the shackles of confinement to fixed dialysis equipment and enjoy increased mobility. (pharmaceutical-business-review.com)
  • Designed for use as a belt, patients can wear this dialysis equipment for slow, gentle dialysis. (pharmaceutical-business-review.com)
  • Given the continuous advancements taking place in medical device technology, wearable dialysis equipment may soon emerge in a more compact and small form factor to provide increased convenience and usability to patients. (pharmaceutical-business-review.com)
  • The integration of portable home haemodialysis equipment facilitating elongated use in homes and offices with wearable artificial kidneys for peritoneal dialysis allowing uninterrupted blood cleansing throughout the day will ensure more patient comfort and guarantee better and enhanced performance of the dialysis equipment. (pharmaceutical-business-review.com)
  • Methodology: The study population included all patients who were seeking dialysis services during one month period of data collection. (scirp.org)
  • Recommendation: The hospital should keep the patients' level of satisfaction high and maintain it through the provision of more dialysis machines and hiring more nurses. (scirp.org)
  • Argentero, P., Dell'Olivo, B. and Ferreti, M.S. (2008) Staff burnout and patient satisfaction with the quality of dialysis care. (scirp.org)
  • Background - Sustained low efficiency dialysis (SLED) has emerged as an alternative to continuous renal replacement therapy (CRRT) for the treatment of acute kidney injury (AKI) in critically ill patients. (ices.on.ca)
  • ESRD patients have an increased risk of cardiovascular death, 10-20 times that of the general public, and are more likely to die of cardiovascular disease than to progress to dialysis [ 1 ] . (medsci.org)
  • This study followed an observational and descriptive data collected in a Private Clinic of Dialysis, Porto Alegre, where 74 ill renal patients underwent hemodialysis. (bvsalud.org)
  • Continued support is still needed to save the lives of the most vulnerable, including renal failure patients. (who.int)
  • Chinese herbs Urinary tract infection Renal insufficiency Dose adjustment. (ajol.info)
  • Chinese herbal medicine was effective and safe in the treatment of UTIs with renal insufficiency. (ajol.info)
  • Most relevant risk factors are active (and passive) smoking, hypertension and overweight, lack of physical exercise and renal insufficiency from any reason ( 1 ). (iiarjournals.org)
  • As Dr. Ziad Hijazi told Reuters Health by email, "Renal dysfunction is a complex issue in patients with atrial fibrillation when balancing the risk of stroke versus the risk of bleeding. (the-hospitalist.org)
  • 2014. Preliminary study on tubuloglomerular dysfunction and evidence of renal inflammation in patients with visceral leishmaniasis. (ajtmh.org)
  • 2011. Renal tubular dysfunction in patients with American cutaneous leishmaniasis. (ajtmh.org)
  • AF is associated with an increased risk of a progressive decline in renal function for all patients and, once they have renal dysfunction, patients with AF are much more likely to progress to end-stage renal disease than those without. (thrombosisadviser.com)
  • Of these, it is crucial to consider the patient's kidneys, not only due to the negative interplay between AF, renal dysfunction and diabetes, but because patients will not regain renal function once it is lost. (thrombosisadviser.com)
  • Of the four patients who underwent systemic therapy, three are still alive at the time of this report. (scirp.org)
  • Overall, the risks of stroke or systemic embolism, major bleeding, and mortality were greater in patients with worsening renal function (hazard ratio, 1.53 for stroke or systemic embolism, 1.56 for major bleeding, and 2.31 for mortality). (the-hospitalist.org)
  • However, such patients on apixaban, compared with warfarin, consistently demonstrated a lower relative risk of stroke or systemic embolism (HR 0.80), ischemic or unspecified stroke (HR 0.88), and major bleeding (HR 0.76). (the-hospitalist.org)
  • The patient had no systemic signs or symptoms. (cdlib.org)
  • Pseudallescheria boydii is an opportunistic fungus that can cause systemic infection mainly in immunocompromised patients that manifests as pulmonary, osteoarticular, ocular, vascular, cutaneous or central nervous system disease. (cdlib.org)
  • Systemic IL-2 is an effective treatment for low to intermediate risk mRCC patients, its efficacy is marginal in high-risk cases. (nih.gov)
  • The aim of this study was to evaluate the efficacy of MTX in a particular group of patients with systemic lupus erythematosus (SLE). (bmj.com)
  • Within this cohort, we assessed 21 patients who received systemic therapy. (simulations-plus.com)
  • Ingestion of ethylene glycol leads to systemic toxicity beginning with CNS effects, followed by cardiopulmonary effects, and finally renal failure. (cdc.gov)
  • A mnemonic for the causes of renal papillary necrosis is POSTCARDS: pyelonephritis, obstruction of the urogenital tract, sickle cell disease, tuberculosis, cirrhosis of the liver, analgesia/alcohol use disorder, renal vein thrombosis, diabetes mellitus, and systemic vasculitis. (wikipedia.org)
  • Of the 4 patients who underwent targeted therapy, the median follow up was 33 months with a median progression free survival of 16 months. (scirp.org)
  • A second patient had long period of stable disease before disease progression. (scirp.org)
  • 8 Therefore, it is of utmost importance to slow or prevent the development and progression of renal disease in a patient like Alex. (thrombosisadviser.com)
  • Autosomal Dominant Polycystic Kidney Disease (ADPKD) Polycystic kidney disease (PKD) is a hereditary disorder of renal cyst formation causing gradual enlargement of both kidneys, sometimes with progression to renal failure. (msdmanuals.com)
  • Progression of renal artery stenosis in patients undergoing cardiac catheterization. (medscape.com)
  • Understandably, my patients with T1D and CKD are frustrated that they are not eligible for these potentially life-changing treatments for CKD that can reduce the progression of CKD and decrease the risk for adverse cardiovascular (CV) and kidney outcomes. (medscape.com)
  • Finerenone targets mineraloreceptor (MR) overactivation, which may contribute to progression of CKD and CVD in patients with diabetes. (medscape.com)
  • In recent years, the advent of targeted therapy has transformed the outcomes of patients with metastatic RCC although little evidence is available on its effectiveness on this subset of patients. (scirp.org)
  • Randomized Phase III Trial of High-Dose Interleukin-2 versus Subcutaneous Interleukin-2 and Interferon in Patients with Metastatic Renal Cell Carcinoma," Journal of Clinical Oncology, Vol. 23, No. 1, 2005, pp. 133-141. (scirp.org)
  • Recombinant Human Interleukin-2, Recombinant Human Interferon Alfa-2a, or Both in Metastatic Renal-Cell Carcinoma," The New England Journal of Medicine, Vol. 338, No. 18, 1998, pp. 1272-1278. (scirp.org)
  • The Phase 3 trial is expected to enroll approximately 322 patients with recurrent or metastatic RCC who have failed at least two prior regimens, including VEGFR-TKI therapy (other than sorafenib). (businesswire.com)
  • A phase I trial was conducted to evaluate the feasibility, safety, and efficacy of a dendritic cell-based vaccination in patients with metastatic renal cell carcinoma (RCC). (aacrjournals.org)
  • Peripheral blood mononuclear cells from 123 patients with metastatic renal cell carcinoma, prior to treatment, were found to have a significantly increased arginase activity. (aacrjournals.org)
  • Objectives: Sarcomatoid metastatic renal cell carcinoma (mRCC) represents an aggressive subset of disease, and a definitive therapeutic strategy is lacking. (simulations-plus.com)
  • Background/Aim: The combination of bevacizumab (BEV) plus interferon alpha-2a (IFN) constitutes an option for first-line treatment of metastatic renal cell carcinoma. (iiarjournals.org)
  • In consequence, actual treatment guidelines ( 12 ) recommend a targeted first-line therapy with VEGFR-inhibitors, like sunitinib ( 9 ), pazopanib ( 10 ), or bevacizumab plus immune stimulative IFN, for patients with advanced or metastatic RCC with low to intermediate risk [per Motzer- or MSKCC-Score ( 13 ) /IDMC score International Metastatic Database Consortium (IMDC) adverse risk factors] ( 8 ). (iiarjournals.org)
  • Prospective Randomized Trial of Interferon Alfa-2a Plus Vinblastine versus Vinblastine Alone in Patients with Advanced Renal Cell Cancer," Journal of Clinical Oncology, Vol. 17, No. 9, 1999, pp. 2859-2867. (scirp.org)
  • The drug cabozantinib alone is already approved by the FDA for use in advanced renal cell cancer. (froedtert.com)
  • Radium-223 dichloride is approved by the FDA, but not for advanced renal cell cancer. (froedtert.com)
  • A 53-year-old man with end-stage renal failure (ESRD) of unknown etiology was on hemodialysis (HD) since 1999. (hindawi.com)
  • We evaluated different immune parameters using a modified cellulose low-flux hemophan vs. synthetic high-flux polyamide membrane during 1 year in 35 stable chronic hemodialysis patients. (scienceopen.com)
  • Although the immunological changes seen in chronic hemodialyzed patients must be interpreted in conjunction with their basal uremic states and the membrane permeability properties, our study suggests that 1-year immunological evaluation of hemodialysis membranes biocompatibility is associated with changes in the pattern of chronic T-cell activation, which is in part related to the use of a particular membrane type. (scienceopen.com)
  • Moreover, some key molecules (CD54) are affected in patients with end-stage renal disease undergoing hemodialysis. (scienceopen.com)
  • To elucidate the involvement of Fas antigen which mediates apoptosis, we analyzed Fas expression on peripheral blood T cells in uremic non-dialyzed (non-HD) patients and hemodialysis (HD) patients. (scienceopen.com)
  • To develop and implement an index of dental risk according to the severity of the lesions present in the oral cavity of pretransplant hemodialysis patients. (bvsalud.org)
  • hemodialysis for some patients. (cdc.gov)
  • The most common cause of renal artery stenosis is a blockage in the the arteries due to high cholesterol. (wikidoc.org)
  • Analgesic nephropathy is a common cause of renal papillary necrosis. (wikipedia.org)
  • the lower limit was defined as the https://www.niddk.nih.gov/health-information/professionals/clinical-tools- difference between the observed number of deaths and the upper patient-management/kidney-disease/identify-manage-patients/manage-ckd/ prepare-kidney-replacement-therapy end of a one-sided 95% prediction interval from the model. (cdc.gov)
  • Tuberculosis is a disease relatively frequent in renal transplant patients, presenting a wide variety of clinical manifestations, often involving various organs and potentially fatal. (hindawi.com)
  • The authors report two cases of isolated gastro-intestinal tuberculosis in renal transplant recipients that illustrates the difficulty of making this diagnosis and a brief review of the literature on its clinical presentation, diagnosis, and therapeutic approach. (hindawi.com)
  • In these patients atypical presentation is the rule and it requires a high clinical suspicion for its diagnosis [ 8 ]. (hindawi.com)
  • The patients with refractory hypertension and PAF simultaneously were common in clinical. (hindawi.com)
  • Phase III Trial of Interferon Alfa-2a with or without 13-Cis-Retinoic Acid for Patients with Advanced Renal Cell Carcinoma," Journal of Clinical Oncology, Vol. 18, No. 16, 2000, pp. 2972-2980. (scirp.org)
  • In a June 15 online paper in JAMA Cardiology , Dr. Hijazi, of Uppsala University Hospital, Sweden, and colleagues report that they came to this conclusion after examining data from a clinical trial (ARISTOTLE) on more than 16,800 AF patients randomized to apixaban or warfarin. (the-hospitalist.org)
  • Commenting on the findings by email, cardiologist Dr. Anil Pandit of Scottsdale, Arizona, told Reuters Health, "The study by Hijazi et al answers very important clinical questions regarding safety and efficacy of apixaban in situations of declining renal function, a common phenomenon in a real world scenario. (the-hospitalist.org)
  • BACKGROUND: For first-line therapy options for advanced renal cell carcinoma (RCC), clinical trials have demonstrated similar efficacy for pazopanib and sunitinib as well as differing side-effect profiles, which may affect patient persistence in self-administration of these oral medications. (rti.org)
  • Aaronson NK: Assessing the quality of life of patients in cancer clinical trials: Common problems and common sense solutions. (karger.com)
  • CONCLUSIONS In an open prospective study methotrexate was used in SLE patients with particular clinical characteristics. (bmj.com)
  • OBJECTIVE: To identify the clinical characteristics, pathological changes, and outcome of patients with primary Sjögren's syndrome (pSS). (jrheum.org)
  • Patients with chronic renal failure (CRF) have low immunity due to the medicines they use, their clinical condition and the treatment itself. (bvsalud.org)
  • Thirteen patients of the Pro-Renal Foundation of Curitiba were selected and submitted to clinical and radiographic examination for the determination of the index of dental risk proposed in this study. (bvsalud.org)
  • 38% of the 13 patients submitted to clinical and radiographic examination were classified as high-risk patients. (bvsalud.org)
  • A clinical-pathologic study in normotensive and hypertensive patients. (medscape.com)
  • Hiddo Heerspink, PhD, PharmD, professor of clinical trials and personalized medicine at University Medical Center in Groningen, Netherlands, surveyed the ongoing clinical trials in patients with T1D and CKD. (medscape.com)
  • She has witnessed the torment of kidney failure patients, and the decreasing capacity of the hospital to treat the patients properly. (who.int)
  • A partnership between WHO, KSrelief and the Government of Kuwait has helped support patients suffering from renal failure in Yemen through the provision of access to healthcare. (who.int)
  • WHO has provided up to US$ 24 million worth in supplies to cover the life-saving treatment needs of patients living with chronic, life-threatening conditions (cancer, kidney failure and noncommunicable diseases, including diabetes). (who.int)
  • The main criticism of the findings of our meta-analysis was inapplicability in the real world scenario, where subclinical episodes of acute kidney injury and worsening renal failure, may lead to increased anticoagulant effect and bleeding," Dr. Pandit said. (the-hospitalist.org)
  • He also pointed out that "the efficacy and safety of apixaban is not established in patients with severe renal failure, … as this group of patients was not studied in the ARISTOTLE trial. (the-hospitalist.org)
  • His past medical history was remarkable for hypertension, ischemic heart disease and chronic renal failure. (cdlib.org)
  • What is the best form of fluid therapy for a chronic renal failure patient who also has heart disease? (vin.com)
  • together with worsening renal perfusion due to forward failure and adaptive mechanisms, serum creatinine levels rise and BUN levels continue to increase. (vin.com)
  • Introduction: Renal failure is on the increase and patients have to identify with renal services and centres where services for renal replacement therapies are rendered. (scirp.org)
  • Relationship between susceptibility to apoptosis and Fas expression in peripheral blood T cells from uremic patients: a possible mechanism for lymphopenia in chronic renal failure. (scienceopen.com)
  • Chronic renal failure (CRF) is often complicated by lymphopenia, which may be partly responsible for immune deficiency. (scienceopen.com)
  • The main outcome was a composite of incident renal replacement therapy (RRT), hospitalisation due to decompensated Heart Failure, new onset atrial fibrillation, pacemaker/ICD implantation, stroke/TIA and death. (uzh.ch)
  • This index may present great value to health professionals in the evaluation, treatment and control of the oral health conditions of chronic renal failure patients. (bvsalud.org)
  • Renal replacement therapy describes the range of therapies designed to remove waste products, such as urea and creatinine, from the blood in cases of kidney failure. (nature.com)
  • Idvall, M 2006, ' The xenotransplantation narratives of nine type 1 diabetic patients with renal failure ', Xenotransplantation , vol. 13, nr. 6, s. 509-511. (lu.se)
  • Captopril was demonstrated to reduce the risk for kidney failure in these patients in 1993. (medscape.com)
  • This aimed at at evaluating the perception of CKDamong newly diagnosed end-stage chronic renal failure patients . (bvsalud.org)
  • If the degree of necrosis is substantial post-renal failure may occur, though this is uncommon. (wikipedia.org)
  • Conclusions - Among critically ill patients with acute kidney injury, mortality at 90 days and one year was not different among patients initiating SLED as compared to CRRT. (ices.on.ca)
  • Renal artery occlusion in patients with renovascular hypertension treated with captopril. (bmj.com)
  • Renal artery occlusion. (bmj.com)
  • In transplanted patients the incidence of this opportunistic agent is even more frequent, with 512 cases/100.000 inhabitants/year and it is often linked to adverse outcomes [ 1 - 3 ]. (hindawi.com)
  • A computerised bibliographic search of Medline, Embase, and Cochrane databases was performed for studies reporting outcomes on BPO treatments in transplanted patients. (urotoday.com)
  • In this report, we looked at the outcomes for transplant patients undergoing medical or surgical management of benign prostatic obstruction. (urotoday.com)
  • 14- 17 There is also evidence that some NOACs may be associated with a reduced risk of adverse renal outcomes compared with vitamin K antagonists (VKAs). (thrombosisadviser.com)
  • The 2019 update to the American Heart Association/American College of Cardiology/Heart Rhythm Society guidelines acknowledges that the NOACs, particularly rivaroxaban and dabigatran, may be associated with a lower risk of adverse renal outcomes than VKAs in patients with AF. (thrombosisadviser.com)
  • Unfortunately, no clinically meaningful benefits of serum urate reduction were found on kidney outcomes with allopurinol in patients with T1D and CKD. (medscape.com)
  • Gastrointestinal tuberculosis, although rare in the general population, is about 50 times more frequent in renal transplant patients. (hindawi.com)
  • To evaluate benefits/harms of BPO treatments in transplant patients by reviewing current literature. (urotoday.com)
  • We conclude that further prospective studies are required for better clarity about timing and modality of intervention in transplant patients. (urotoday.com)
  • The End-Stage Renal Disease Symptom Checklist - Transplantation Module (ESRD-SCL ® ) was developed to assess the specific physical and psychological quality of life of renal transplant recipients, with a special focus on side effects of immune system suppression therapy. (karger.com)
  • According to the pathologies diagnosed, the index of dental risk of the patients can be classified as low, medium or high, which indicates the need for dental treatment prior to renal transplantation. (bvsalud.org)
  • 7-9 These patients' renal values rise significantly at the onset of CHF, at which time the confounding influence of diuretics may also contribute to azotemia.8 BUN (but not necessarily creatinine) is elevated thereafter. (vin.com)
  • The thyroid state significantly influences renal function. (medscimonit.com)
  • The combination of corticosteroids and immunosuppressors significantly improves the renal function of patients with pSS. (jrheum.org)
  • When two uremic groups were compared, Fas intensity on T cells was significantly higher in non-HD patients than in patients on HD. (scienceopen.com)
  • Forty-one patients underwent renal biopsies. (jrheum.org)
  • In patients with renal disorders, symptoms and signs may be nonspecific, absent until the disorder is severe, or both. (msdmanuals.com)
  • Longer overall survival (28.7 months, 95% CI=24.5-38.3) probably is an effect of patient characteristics and follow-up therapies. (iiarjournals.org)
  • There have been no new therapies for patients with T1D and CKD for three decades, said Heerspink. (medscape.com)
  • Among the main barriers to developing new therapies for patients with T1D and CKD are the endpoints often used to investigate a new drug: end-stage kidney disease (ESKD) and doubling of serum creatinine. (medscape.com)
  • A multicentre comparative cohort study is needed to draw firm conclusions about the ideal treatment for BPO in RT patients. (urotoday.com)
  • Conclusions: Compared with previous series and prospective trials assessing patients with sarcomatoid mRCC, the observed survival was prolonged. (simulations-plus.com)
  • February-August 2020) were expressed as a range based on * Renal replacement therapy is the broad name for any of the treatment choices methodology established by CDC ( 7 ). (cdc.gov)
  • Fluid management of the pediatric surgical patient represents an important aspect of medical care, particularly for initial treatment of the ill child. (medscape.com)
  • As a health worker, witnessing my patients' health condition stabilize and improve through treatment is what gives me the energy to continue my mission despite the hardship," says Dheya. (who.int)
  • In the treatment of refractory hypertension, renal artery ablation (RDN) has become the most important nonpharmaceutical treatment modality [ 1 - 3 ]. (hindawi.com)
  • Surgical resection has been the treatment of choice because of superior patient survival compared with traditional immunotherapy. (scirp.org)
  • Two patients did not undergo further treatment. (scirp.org)
  • Eligible patients may also have received checkpoint inhibitor therapy in earlier lines of treatment. (businesswire.com)
  • While significant advances have been made in the treatment of renal cancer, there remains a need for effective yet more tolerable treatments, both for single agent and combination use," said Brian Rini, M.D., Professor of Medicine at the Cleveland Clinic Lerner College of Medicine. (businesswire.com)
  • The company is focused on developing and commercializing its lead candidate tivozanib, a potent, selective, long half-life inhibitor of vascular endothelial growth factor 1, 2 and 3 receptors, in North America as a treatment for renal cell carcinoma and other cancers. (businesswire.com)
  • NEW YORK - In patients with atrial fibrillation (AF) and a wide range of renal function, compared to warfarin, treatment with apixaban reduces the risk of cardiovascular events, according to multinational investigators. (the-hospitalist.org)
  • Darmstadt, Germany and New York, US, May 14, 2019 - Merck KGaA, Darmstadt, Germany, which operates its biopharmaceutical business as EMD Serono in the US and Canada, and Pfizer Inc. (NYSE: PFE) today announced that the US Food and Drug Administration (FDA) has approved BAVENCIO® (avelumab) in combination with INLYTA® (axitinib) for the first-line treatment of patients with advanced renal cell carcinoma (RCC). (pfizer.com)
  • This outcome study suggests that administration of rhIL-2 by inhalation is efficacious and safe in high-risk mRCC patients with pulmonary metastases, who have no other treatment option available. (nih.gov)
  • For the many patients with mild disease who are well managed with symptomatic treatment and antimalarial drugs, there is certainly no need for intensification of treatment. (bmj.com)
  • The purpose of this study was to investigate if these patients might profit from low dose methotrexate treatment. (bmj.com)
  • 22 When stroke/SE prevention, risk of bleeding and renal preservation are considered in totality, the NOACs present an appealing treatment option for those with AF. (thrombosisadviser.com)
  • Most of the patients responded symptomatically to treatment. (ajol.info)
  • Chinese herbs eradicated the primary pathogen in 68.7% of the patients at the day 10 of treatment. (ajol.info)
  • Two patients demonstrated slight increases in serum creatinine on day 10 of treatment. (ajol.info)
  • Results: Of the 21 patients assessed, 2 patients received chemotherapy, 7 patients received immunotherapy, and 12 patients received targeted agents as their first line treatment. (simulations-plus.com)
  • Plouin PF, Bax L. Diagnosis and treatment of renal artery stenosis. (medscape.com)
  • In the patient groups who showed an annual eGFR decline of ≥3 and 1-3 mL/min/1.73 m2 , there was a significant slowing of the decline after SGLT2is therapy , compared with before the treatment (P (bvsalud.org)
  • In that regard, one thing that has really come to the fore is not only do we start treatment regardless of CD4 count, but we also often start as soon as a patient is ready to start, as soon as they want to start - sometimes even on the same day or in the same few days after diagnosis, as long as you can line up the insurance. (medscape.com)
  • The diagnosis of renal papillary necrosis is therefore done via: Urinalysis Blood cell count Urine cytology study Imaging study (with intravenous contrast) Cystoscopy Ureteroscopy Treatment of renal papillary necrosis is supportive, any obstruction (urethral) can be dealt with via stenting. (wikipedia.org)
  • The number of patients unable to access treatment outside the Gaza Strip increased during the second half of 2007. (who.int)
  • The incidence of this infection has become elevated in parallel with the increased numbers of immunocompromised patients, particularly solid organ transplant recipients [ 2 , 3 , 4 , 5 ]. (cdlib.org)
  • We evaluated the impact of cardio-renal syndrome(CRS) on the incidence of major cardiovascular complications and death in a prospective FD cohort. (uzh.ch)
  • We describe the case of a 59-year-old male renal transplant recipient who presented with a 1 month history of nodular, erythematous, and crusted lesions on the anterior surface of the left leg. (cdlib.org)
  • The patient underwent surgical excision of the lesions combined with voriconazole 400 mg/day for 2 months. (cdlib.org)
  • After this period no new lesions appeared and the patient has remained without recurrence after 2 years of follow-up. (cdlib.org)
  • A 59-year-old male patient, renal transplant recipient for about 4 years, presented with a 1-month history of three lesions on the anterior aspect of his left leg. (cdlib.org)
  • Researchers have studied the natural history of atherosclerotic renal artery stenosis by obtaining images from sequential abdominal aortographs or duplex ultrasound scans in patients with documented renal artery lesions who have been treated medically. (medscape.com)
  • In a study of 85 patients at the Cleveland Clinic who were followed for 3-172 months, patients with mild-to-moderate stenosis remained unchanged upon follow-up, and 39% of patients with greater than 75% lesions progressed to total occlusion. (medscape.com)
  • The patient had no diarrhea, urinary symptoms, graft pain or other complaints. (hindawi.com)
  • Despite this, alpha-blockers, TUIP, and TURP showed a beneficial increase in the peak urinary flow and reduced symptoms in transplants patients with BPO. (urotoday.com)
  • Symptoms of depression are often diagnosed in these patients, symptoms that affect their adherence and quality of life, negatively affecting the course of the disease. (bvsalud.org)
  • Evaluation of the Urologic Patient Urologic patients may have symptoms referable to the kidneys as well as to other parts of the genitourinary tract (GU) tract. (msdmanuals.com)
  • I've seen a patient with acute HIV who had meningoencephalitis, and certainly that's the kind of patient for whom ART will treat their symptoms and their condition. (medscape.com)
  • Even if the patient doesn't have symptoms, there's a lot of good theoretical reasons to treat acute HIV. (medscape.com)
  • Symptoms (and signs) consistent with renal papillary necrosis are: Back pain Cloudy urine Tissue pieces (in urine) Fever Painful/frequent urination Urinary incontinence In terms of cause, almost any condition that involves ischemia can lead to renal papillary necrosis. (wikipedia.org)
  • In this post-hoc analysis from the PERson-centredness in Hypertension management using Information Technology (PERHIT) study, we aimed to explore BPV in daily home measurements in hypertensive patients from primary care, to identify factors associated with high BPV and to investigate whether estimated glomerular filtration rate (eGFR) and pulse pressure, as markers of target organ damage (TOD), are associated with BPV. (lu.se)
  • Renal artery denervation (RDN) can treat hypertension and paroxysmal atrial fibrillation (PAF). (hindawi.com)
  • The study aimed to evaluate the effect of RDN on cardiac diastolic function in patients with refractory hypertension and PAF. (hindawi.com)
  • 190 consecutive patients with hypertension and PAF were recruited. (hindawi.com)
  • The levels of NT-proBNP and metrics of echocardiography were measured before and after RDN in patients with refractory hypertension and PAF. (hindawi.com)
  • RDN could improve the diastolic function in patients with refractory hypertension and PAF. (hindawi.com)
  • In this study, we studied the changes in diastolic function in patients with refractory hypertension and PAF before and after RDN. (hindawi.com)
  • In patients with CRS, the risk to develop events was significantly increased if adjusted for demographics and RRT (HR 4.46 [1.07-18.62], P = 0.04), approaching significance if additionally adjusted for hypertension (HR 4.05 [0.95-17.29], P = 0.06). (uzh.ch)
  • In South Africa, the prevalence of dyslipidaemia and hypertension (HT) in paediatric diabetes patients is unknown. (who.int)
  • 1-6 The cardiorenal syndrome, then, presents at least two aspects of care that are of interest to use as small animal clinicians: approaches that can help avoid or delay its onset, and methods for managing patients who have developed it despite precautions and optimal care. (vin.com)
  • Methods - We conducted a retrospective cohort study of patients with AKI who commenced either SLED or CRRT in ICUs at a tertiary care hospital in Toronto, Canada. (ices.on.ca)
  • METHODS: All patients with pSS and renal involvement who were admitted to Ruijin Hospital from April 1993 to December 2006 were included. (jrheum.org)
  • Methods and results: A total of 104 genetically proven FD patients were annually followed at the University Hospitals Zurich and Bern. (uzh.ch)
  • Materials and methods: From an institutional database including 270 patients with mRCC, we identified 34 patients with documented sarcomatoid features. (simulations-plus.com)
  • Renal handling of water is related to glomerular filtration and tubular function. (medscape.com)
  • Desirudin reduced major venous thromboembolism (VTE) and post-operative bleeding compared with the standard of care, enoxaparin, in patients with poor kidney function undergoing orthopedic surgery, according to a poster presented at the Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) meeting. (news-medical.net)
  • Entitled The Impact of Renal Function on Options for Venous Thromboembolism Prophylaxis Following Major Orthopedic Surgery: Insights from a Randomized Trial , the poster was presented at ATVB's annual meeting in Chicago on April 29. (news-medical.net)
  • While we've long been concerned about the safety of anticoagulants in patients with poor kidney function, this is the first analysis to report a lack of efficacy with standard heparin therapy in this patient population,' says Michael Kurz, PhD, one of the authors and Vice President, Global Medical Affairs of Canyon, desirudin's manufacturer. (news-medical.net)
  • Desirudin provided consistent VTE prevention irrespective of renal function. (news-medical.net)
  • The 190 patients were divided into the decreasing HR and nondecreasing HR group, the decreasing MAP and nondecreasing MAP group, the HFPEF group, and the normal diastolic function group, respectively. (hindawi.com)
  • Theoretically, the RDN also has a certain effect on cardiac diastolic function in these patients. (hindawi.com)
  • This study," he added, "shows that apixaban, compared with warfarin, was associated with a lower risk of stroke, death, and major bleeding, regardless of changes in renal function over time. (the-hospitalist.org)
  • Over the course of a year, about a quarter (26%) maintained good renal function. (the-hospitalist.org)
  • The decline in renal function was more rapid in patients who were older or had comorbidities. (the-hospitalist.org)
  • In fact, as well as showing benefit in this group of patients, the researchers conclude, "The superior efficacy and safety of apixaban as compared with warfarin were similar in patients with normal, poor, and worsening renal function. (the-hospitalist.org)
  • 2 The problem of suboptimal renal function in small animal patients with heart disease is a widely prevalent one, likely with adverse consequences similar to those seen in human medicine. (vin.com)
  • Renal cortical perfusion is independently associated with free thyroxine, which can contribute to renal function abnormalities in the condition of impaired thyroid function. (medscimonit.com)
  • Eighteen recovered renal function. (jrheum.org)
  • When is the right time to start thinking about renal function in patients with AF? (thrombosisadviser.com)
  • Patient case: When does renal function begin to affect prognosis? (thrombosisadviser.com)
  • Renal function also declines naturally with age , meaning that there are unlikely to be improvements when a patient has reached the stage of impaired function. (thrombosisadviser.com)
  • What can be done early to prevent renal function decline? (thrombosisadviser.com)
  • Further encouraging data were found in a subset of patients with AF who were at increased risk of stroke/SE due to a combination of impaired renal function and diabetes. (thrombosisadviser.com)
  • A total of 33 adult female patients with moderately impaired renal function and symptomatic UTIs were included in this study. (ajol.info)
  • For CsA, POR*28/*28 patients not expressing CYP3A5 and not carrying the CYP3A4*22 decrease-of-function allele showed 15% lower CsA dose-adjusted predose concentrations (P = 0.01), indicating also increased CYP3A4 activity. (eur.nl)
  • Chronic Kidney Disease Chronic kidney disease (CKD) is long-standing, progressive deterioration of renal function. (msdmanuals.com)
  • Decrease dosage in patients with impaired renal function. (cdc.gov)
  • Drugs that decrease renal function could decrease clearance. (cdc.gov)
  • 8.7-12.9 excess deaths per 1,000 ESRD patients, or a total of therapy* is required to sustain life ( 1 ). (cdc.gov)
  • Infants and children are sensitive to small degrees of dehydration , and commonly used protocols for pediatric fluid therapy do not consider the rapidly changing perioperative physiology in this patient population. (medscape.com)
  • Therapeutic options may be a problem in the context of an immunosuppressed patient, requiring adjustment of maintenance therapy. (hindawi.com)
  • Our results demonstrate that targeted therapy can be efficacious in some patients where surgical resection is not suitable or possible. (scirp.org)
  • K. Chiu, A. Razack and A. Maraveyas, "Targeted Therapy in the Management of Elderly Patients with Pancreatic Metastases from Renal Cell Carcinoma," Journal of Cancer Therapy , Vol. 4 No. 9B, 2013, pp. 15-21. (scirp.org)
  • This is the first FDA approval for an anti-PD-L1 therapy as part of a combination regimen for patients with advanced RCC. (pfizer.com)
  • Should a cardiac patient who is azotemic be given fluid therapy as a form of renal protection? (vin.com)
  • 0.05) by drug cohort in the duration of index drug therapy or the percentage of patients who discontinued their index drugs. (rti.org)
  • Because of the paucity of published data it is uncertain which patients actually profit from MTX therapy. (bmj.com)
  • Two patients relapsed (one had abbreviated courses of therapy) 6 to 8 days posttreatment. (ajol.info)
  • Use of Doppler ultrasonography to predict the outcome of therapy for renal-artery stenosis. (medscape.com)
  • Tragically, most patients with CKD die from a CV event well before they need renal replacement therapy. (medscape.com)
  • This study aimed to determine the effects of the CXC chemokine ligand 16 (CXCL16)/CXC chemokine receptor 6 (CXCR6) pathway on cholesterol accumulation in the radial arteries of end-stage renal disease (ESRD) patients with concomitant microinflammation and to further investigate the potential effects of the purinergic receptor P2X ligand-gated ion channel 7 (P2X7R). (medsci.org)
  • Surgically removed tissues from the radial arteries of patients receiving arteriovenostomy were used for preliminary evaluation of AS. (medsci.org)
  • Furthermore, CXCL16 expression was positively correlated with P2X7R expression in the radial arteries of ESRD patients. (medsci.org)
  • Inflammation contributed to foam cell formation in the radial arteries of ESRD patients via activation of the CXCL16/CXCR6 pathway, which may be regulated by P2X7R. (medsci.org)
  • Stenting atherosclerotic renal arteries: time to be less aggressive. (medscape.com)
  • Renal artery stenosis is a narrowing or blockage of the artery that supplies blood to the kidneys. (wikidoc.org)
  • A retrospective study of 154 diabetic patients, aged 1 - 19 years, seen at TBH between 2007 and 2017, was undertaken. (who.int)
  • The mortality rate for 6,953-10,316 excess deaths in a population of 798,611 ESRD patients with ESRD in the United States has been declining since patients during February 1-August 31, 2020. (cdc.gov)
  • However, during the COVID-19 pandemic, ESRD suggest that deaths among ESRD patients during the early phase patients are at high risk for COVID-19-associated morbidity of the pandemic exceeded those that would have been expected and mortality, which is due, in part, to weakened immune based on previous years' data. (cdc.gov)
  • ESRD NCC importance of data-driven technical assistance and further analy- analyzed deaths reported to the Consolidated Renal Operations ses of the causes and patterns of excess deaths in ESRD patients. (cdc.gov)
  • The ESRD-SCL was found to have adequate reliability, test-retest correlations in a subsample of 88 stable patients after 1 year, and construct validity. (karger.com)
  • Forty-three ESRD patients were divided into the control group (n=17) and the inflamed group (n=26) based on plasma C-reactive protein (CRP) levels. (medsci.org)
  • Cardiovascular disease is the most common cause of death for patients with end-stage renal disease (ESRD). (medsci.org)
  • The role of fibrosis in early progressive renal decline in type 2 diabetes is unknown. (diabetesjournals.org)
  • But studies have focused mainly on patients with type 2 diabetes (T2D), and patients with type 1 diabetes (T1D) have largely been left out. (medscape.com)
  • However there remains a group of patients with moderate non-life threatening disease, which nevertheless has a high morbidity. (bmj.com)
  • Adverse reactions observed among the 30 patients were rare. (ajol.info)
  • Benefits and Harms of Benign Prostatic Obstruction Treatments in Renal Transplanted Patients. (urotoday.com)
  • Most studies show that progressive arterial obstruction occurs in 42-53% of patients with atherosclerotic renal artery stenosis, often within the first 2 years of radiographic follow-up. (medscape.com)
  • This prospective study aimed to test the association between renal cortical perfusion (RCP) estimated in color Doppler sonographic dynamic tissue perfusion measurement (DTPM) with thyroid hormones in 36 patients treated with levothyroxine following total thyroidectomy for resectable thyroid cancer. (medscimonit.com)
  • This small prospective study from a single center showed that the renal cortex's color Doppler sonographic dynamic tissue perfusion measurement had very good intraobserver reproducibility. (medscimonit.com)
  • Bremer BA: Absence of control over health and the psychological adjustment to end-stage renal disease. (karger.com)
  • R. I. Fisher, S. A. Rosenberg and G. Fyfe, "Long-Term Survival Update for High-Dose Recombinant Interleukin-2 in Patients with Renal Cell Carcinoma," The Cancer Journal From Scientific American, Vol. 6, Suppl. (scirp.org)
  • The median survival time for patients with multiple myeloma was 592 days (95% confidence interval, 229-955). (hkmj.org)
  • Patients with a creatinine level of less than 400 µmol/L had longer survival (P=0.042). (hkmj.org)
  • In the phase III EVEREST trial reported in The Lancet , Christopher W. Ryan, MD , and colleagues found that adjuvant everolimus was not associated with a significant improvement in event-free survival vs placebo in patients at high risk of disease recurrence following surgery for renal cell carcinoma. (ascopost.com)
  • The investigators concluded, "Postoperative everolimus did not improve recurrence-free survival compared with placebo among patients with renal cell carcinoma at high risk of recurrence after nephrectomy. (ascopost.com)
  • In Kaplan-Meier-Analysis, the poorest event-free survival was observed among patients with CRS. (uzh.ch)
  • Relative 5-year survival rate is 77% in male and female patients, as well ( 1 ). (iiarjournals.org)
  • Eventually, the dichotomy between preserving adequate renal perfusion and avoiding fluid congestion/CHF marks the onset of the cardiorenal syndrome. (vin.com)
  • A total of 755 patients in the everolimus group and 744 in the placebo group were eligible for inclusion in an efficacy analysis. (ascopost.com)
  • We report the case of a renal transplant recipient with cutaneous infection caused by Pseudallescheria boydii . (cdlib.org)
  • It is common for cardiac disorders and renal disorders to coexist in small animal patients. (vin.com)
  • Are there early warning signs that can be identified prior to respiratory problems if one is especially concerned about IV fluid intolerance in a cardiac-renal patient? (vin.com)
  • The management of chronic kidney disease (CKD) in patients with diabetes has been transformed over the past 4 years. (medscape.com)
  • Nineteen (29.7%) patients had serum creatinine levels of greater than 177 µmol/L at presentation. (hkmj.org)
  • In view of the natural history of RVD, patients require serial determinations of serum creatinine levels. (medscape.com)
  • Ninety-four high-risk patients with RCC and pulmonary metastases were treated with inhaled plus concomitant low-dose subcutaneous rhIL-2. (nih.gov)
  • All patients received MTX orally at a dose of 15 mg/week over six months. (bmj.com)
  • After five dendritic cell injections, patients additionally received three injections weekly of low-dose interleukin-2 (1 million IE/m 2 ). (aacrjournals.org)
  • SAF), 354 patients had at least one post-dose effectiveness assessment and formed the full analysis set (FAS) of the final analysis. (iiarjournals.org)
  • If patients experience rash during the two-week lead-in period of once-daily dosing their nevirapine dose should not be increased until the rash has resolved. (who.int)
  • Note: may need higher dose in patients with central nervous system disease. (cdc.gov)
  • The pancreas is an uncommon but recognizable site for metastases from renal cell carcinoma (RCC). (scirp.org)
  • We report our experience of 6 patients with pancreatic RCC metastases. (scirp.org)
  • Four patients were asymptomatic at the time of diagnosis, one presented with obstructive jaundice and another with acute gastrointestinal bleed. (scirp.org)
  • All patients had an established diagnosis of SLE as defined by the American College of Rheumatology 1982 criteria. (bmj.com)
  • Minimally invasive diagnosis of renal artery stenosis by spiral computed tomography angiography. (medscape.com)
  • All 6 patients had a primary RCC of clear cell type. (scirp.org)
  • CAMBRIDGE, Mass.--( BUSINESS WIRE )--AVEO Oncology (NASDAQ:AVEO) today announced that the first patient has been dosed in the Company's pivotal TIVO-3 trial, a randomized, controlled, multi-center, open-label study to compare tivozanib to sorafenib in subjects with refractory advanced renal cell carcinoma (RCC). (businesswire.com)
  • Tivozanib has been investigated in several tumors types, including renal cell, colorectal and breast cancers. (businesswire.com)
  • These results do not support the adjuvant use of everolimus for renal cell carcinoma after surgery. (ascopost.com)
  • Although arginase activity has been described in cancer patients, it is thought to originate from tumor cells metabolizing arginine to ornithine needed to sustain rapid cell proliferation. (aacrjournals.org)
  • The goal of this study was to determine whether myeloid suppressor cells producing high arginase existed in renal cell carcinoma patients. (aacrjournals.org)
  • These patients had a markedly decreased cytokine production and expressed low levels of T cell receptor CD3ζ chain. (aacrjournals.org)
  • Renal cell carcinoma (RCC) has been predicted to occur in 9,900 men and 5,200 women in Germany for the year 2018, whereas in 2015, 3,306 deaths from renal carcinoma in men and 2,106 in women were documented by the German Robert Koch Institute ( 1 ). (iiarjournals.org)
  • among these, about 80% are clear cell renal carcinomas histologically ( 2 ). (iiarjournals.org)