• Docetaxel-based chemotherapy regimens have substantially improved survival and recurrence rates for cancer patients. (hindawi.com)
  • Systemic adjuvant chemotherapy with anthracycline- and taxane-containing regimens has become the standard first line treatment for early and metastatic breast cancer [ 5 ], with large phase III randomized trials showing extremely high long-term disease-free survival and overall survival rates (resp. (hindawi.com)
  • In fact, reducing the planned dose intensity of systemic adjuvant chemotherapy regimens by as little as 15% has been shown to significantly reduce time to progression and overall survival rates in women with metastatic breast cancer [ 5 ]. (hindawi.com)
  • G-CSFs have been shown to reduce overall mortality risk [ 8 , 11 ], reduce the incidence of other adverse events (grade 2 or greater anaemia, asthenia, anorexia, myalgia, nail disorders, and oral mucositis) associated with docetaxel-based chemotherapy regimens, and increase health related quality of life and consequently treatment compliance [ 8 , 12 ]. (hindawi.com)
  • All of them received 6 administrations of the 5-FU based regimens. (medscimonit.com)
  • Meta-analyses have shown that the benefit is only observed for chemotherapy regimens including cisplatin. (bcan.org)
  • Yet at the very same time, these same oncologists will scare patients into signing up for chemotherapy regimens even when their chances of survival on this antiquated protocol are next to nil. (naturalnews.com)
  • However, there are no data in literature reporting the patient's tolerance and response to subsequent lines of chemotherapy after receiving metronomic regimens. (scirp.org)
  • Hence, there is a need to explore new chemotherapy-free regimens for treating chemotherapy intolerant patients. (frontiersin.org)
  • Various chemotherapy regimens were used. (biomedcentral.com)
  • 7 , 8 , 10 , 11 However, the rates of chemotherapy-induced FN reported in RCTs vary considerably for commonly used chemotherapy regimens. (jnccn.org)
  • 2] Many chemotherapy regimens have been investigated for NSCLC, but the ability of these treatments to improve overall survival is debatable. (cancernetwork.com)
  • The primary endpoint analysis of RTOG 0247 examined the pathologic complete remission (pCR) rates of two concurrent neoadjuvant chemotherapy regimens to determine which regimen should be studied further. (appliedradiationoncology.com)
  • Our new analysis of RTOG 0247 provides us with favorable efficacy results of two preoperative chemotherapy regimens used in conjunction with radiation therapy protocols," said Neal J. Meropol, MD, co-author of the study, and the Dr. Lester E. Coleman Jr., Professor of Cancer Research and Therapeutics and chief of the Division of Hematology and Oncology at University Hospitals Case Medical Center and Case Western Reserve University in Cleveland. (appliedradiationoncology.com)
  • This is a Phase 2, open-label, single arm study to evaluate the safety and efficacy of niraparib in ovarian cancer patients who have received three or four previous chemotherapy regimens. (stanford.edu)
  • Patients Must have completed 3 or 4 previous chemotherapy regimens. (stanford.edu)
  • 2.Patient has stage IIIB or IV diagnosis and must have received one or two prior regimens (including platinum- doublet) of cytotoxic chemotherapy for the treatment of locally advanced or metastatic NSCLC. (who.int)
  • Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML): Monitor patients with breast and lung cancer using UDENYCA in conjunction with chemotherapy and/or radiotherapy for signs and symptoms of MDS/AML. (drugs.com)
  • Radiotherapy is used in 50% of all cancer patients. (brainstrust.org.uk)
  • The integration of combination chemotherapy and radiotherapy (RT) has now become a standard of care for patients with locally advanced NSCLC. (cancernetwork.com)
  • All patients were given chemotherapy before and after surgery and radiotherapy. (news-medical.net)
  • Patients had not received neoadjuvant radiotherapy or chemotherapy. (medscape.com)
  • Patients must not have received pelvic radiotherapy as treatment for primary or recurrent disease within 1 year of the first dose of study treatment. (stanford.edu)
  • Granotax was a prospective, open label, multicentre, national phase IV study that evaluated the incidence and severity of neutropenia in adult patients with solid tumors being treated with a docetaxel-based regimen while receiving the GCSF lenograstim. (hindawi.com)
  • The low incidence of adverse effects and chemotherapy dose changes, delays, and withdrawals supports the use of lenograstim as effective primary prophylaxis in South African patients being treated with a docetaxel-based regimen. (hindawi.com)
  • Chemotherapy should be continued a minimum of six weeks before removing patients from a docetaxel-based regimen. (springer.com)
  • However, the chemotherapy administration time and the optimal chemotherapy regimen to be delivered are not yet determined. (bcan.org)
  • The most commonly used chemotherapy regimen was the BFM-95 protocol. (bvsalud.org)
  • Twenty six (65%) patients had the opportunity to receive a classic chemotherapy regimen following metronomic regimen interruption. (scirp.org)
  • There is a need to explore long-term treatments of chemotherapy-free regimen of chronic kidney disease in recurrent ovarian cancer. (frontiersin.org)
  • The patient accepted Niraparib-based treatment regimen after multi-line chemotherapy-induced stage 4 chronic kidney disease. (frontiersin.org)
  • Niraparib-based treatment regimen may be a good choice for patients with well-differentiated serous adenocarcinoma of the ovary who are intolerant to chemotherapy. (frontiersin.org)
  • The study reopened in April 2005 with an amended chemotherapy regimen. (appliedradiationoncology.com)
  • Based on these findings, researchers theorized that the triplet regimen tremelimumab, durvalumab and chemotherapy may improve clinical outcomes for hard-to-treat subgroups of patients with metastatic NSCLC. (ecancer.org)
  • Notably, landmark 24-month overall survival rates were higher with tremelimumab, durvalumab and chemotherapy versus chemotherapy across all subgroups, including those with KRASm, STK11m and KEAP1m, suggesting sustained benefit with the triplet regimen," Dr. Peters reported. (ecancer.org)
  • Yagoda A, Petrylak D (1993) Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer. (springer.com)
  • Entitled The Contribution of Cytotoxic Chemotherapy to 5-year Survival in Adult Malignancies , the paper estimated chemotherapy to be between 2.1 and 2.3 percent effective in treating adult cancers. (naturalnews.com)
  • As the 5-year relative survival rate for cancer in Australia is now over 60%, it is clear that cytotoxic chemotherapy only makes a minor contribution to cancer survival. (naturalnews.com)
  • Purpose: Low-dose metronomic chemotherapy is an emergent treatment schedule in which low doses of cytotoxic agents are given orally continuously, with no or short drug-free intervals. (scirp.org)
  • Do not administer between 14 days before and 24 hours after administration of cytotoxic chemotherapy. (drugs.com)
  • Acral erythema is a common adverse reaction to cytotoxic chemotherapy drugs, particularly cabozantinib, cytarabine, doxorubicin, and fluorouracil and its prodrug capecitabine. (wikipedia.org)
  • Endoscopic Evaluation of Pathological Complete Response Using Deep Neural Network in Esophageal Cancer Patients Who Received Neoadjuvant Chemotherapy-Multicenter Retrospective Study from Four Japanese Esophageal Centers. (bvsalud.org)
  • Detecting pathological complete response ( pCR ) before surgery would facilitate nonsurgical approach after neoadjuvant chemotherapy (NAC). (bvsalud.org)
  • A total of 207 patients (Study Group n=54, Historical Group n=153) with metastatic colorectal cancer were enrolled. (medscimonit.com)
  • Oudard S, Banu E, Beuzeboc P et al (2005) Multicenter randomized phase II study of two schedules of docetaxel, estramustine, and prednisone versus mitoxantrone plus prednisone in patients with metastatic hormone-refractory prostate cancer. (springer.com)
  • Kreis W, Budman DR, Fetten J et al (1999) Phase I trial of the combination of daily estramustine phosphate and intermittent docetaxel in patients with metastatic hormone refractory prostate carcinoma. (springer.com)
  • It is well known that all these low-dose schedules have a favorable safety profile and may provide an adequate tumor control in patients with metastatic breast cancer. (scirp.org)
  • Methods: We retrospectively analyzed 40 patients with metastatic breast cancer treated with low doses of Cyclophosphamide and/or Methotrexate and/or Capecitabine in a single center from June 2009 to April 2014. (scirp.org)
  • We evaluated the relationships between clinical status, laboratory factors and progression free survival (PFS), and overall survival (OS) in patients with recurrent or metastatic gastric cancer receiving first-line palliative chemotherapy. (biomedcentral.com)
  • The results of this study showed that the presence of a systemic inflammatory response as evidenced by the CRP, GPS was significantly associated with shorter PFS and OS in patients with recurrent or metastatic gastric cancer receiving first-line palliative chemotherapy. (biomedcentral.com)
  • Bone metastasis and GPS were very useful indicator for survival in patients with recurrent or metastatic gastric cancer receiving palliative chemotherapy. (biomedcentral.com)
  • Recurred or metastatic gastric cancer has a very poor prognosis, but chemotherapy can improve survival and possibly provide significant palliation of symptoms. (biomedcentral.com)
  • A meta-analysis (n = 52 randomized trials encompassing 9,387 patients) of the Non-Small-Cell Lung Cancer Collaborative Group indicated that cisplatin- based chemotherapy provides a significant survival benefit for patients with locally advanced or metastatic disease. (cancernetwork.com)
  • The RATIONALE 305 results offer tislelizumab plus chemotherapy as a new first-line treatment option for patients with PD-L1-positive, unresectable, locally advanced or metastatic gastric or gastroesophageal junction cancer. (ascopost.com)
  • The immunotherapy has already been approved for several other NSCLC indications , including as first-line treatment along with pemetrexed and platinum chemotherapy for patients with metastatic nonsquamous NSCLC without EGFR or ALK genomic tumor aberrations. (medscape.com)
  • In previously reported results of the phase 3 POSEIDON trial, patients with EGFR/ALK wild-type metastatic NSCLC who were given first-line tremelimumab, durvalumab and chemotherapy demonstrated statistically significant improvements in both progression-free survival and overall survival versus chemotherapy alone. (ecancer.org)
  • Our analysis supports using combined therapy of tremelimumab, durvalumab and chemotherapy as a potential first-line treatment option for patients with metastatic NSCLC, including those with KRASm, STK11m or KEAP1m tumours," Dr. Peters reported. (ecancer.org)
  • The results from this prevali- the field of cancer biomarkers (11-13), and that approach was dation study showed that patients could be classified into high- adopted here to define predictive serum biomarkers associated versus low-risk groups for developing metastatic breast cancer with tumor relapse in breast cancer patients. (lu.se)
  • 4.Patients must have received previous treatment with crizotinib for the treatment of locally advanced or metastatic NSCLC. (who.int)
  • Furthermore, lenograstim may increase the patient's exposure to chemotherapy allowing patients to receive optimal dosing and duration of treatment, benefitting survival. (hindawi.com)
  • Patients were evaluated based on modified criteria from the Prostate-Specific Antigen Working Group regarding survival and toxicity. (springer.com)
  • In contemporary series, specific survival rates are about 60 to 65% at 5 years, decreasing for locally advanced disease to 45-50% in patients with nonorgan-confined lymph-node negative tumours and to 30-35% in patients with lymph node positive tumours. (bcan.org)
  • Thanks to randomized trials and meta-analysis, it can be concluded that perioperative chemotherapy increases overall survival with an absolute benefit of 5%, equating to a survival rate of 50% at 5 years for nonorgan-confined tumours. (bcan.org)
  • Investigators therefore designed a randomized phase III study to compare the efficacy of GC and HD-MVAC in term of progression-free survival in patients for whom chemotherapy has been decided, before or after radical cystectomy. (bcan.org)
  • The number of patients is based on the median progression-free survival rate of 50% at 3 years observed in patients treated with GC (standard arm A) in the perioperative setting. (bcan.org)
  • With an estimated uniform accrual rate of 140 patients per year for 3.5 years and exponential survival, the final analysis is expected to occur 8 years after the start of the trial. (bcan.org)
  • Treated with afatinib combined with chemotherapy, both patients responded well and achieved progression-free survival. (frontiersin.org)
  • According to the public cases, five patients with Ex19del/G724S treated with afatinib monotherapy achieved an average of only four months of progression-free survival (PFS)(2). (frontiersin.org)
  • Despite the advances in diagnosis method that have been used to control the mortality, most patients still have a poor prognosis and high death rates, with an overall 5-year survival rate of 10% to 15% [ 3 ]. (hindawi.com)
  • A subsequent meta-analysis conducted by researchers from Australia looked at the five-year survival rates of cancer patients undergoing chemotherapy, and their conclusions were even more damning. (naturalnews.com)
  • However, many of the chemotherapeutic agents are nephrotoxic and can promote kidney dysfunction, which affect the efficacy of cancer treatment and the survival of the patient. (frontiersin.org)
  • inhibits tumor angiogenesis and growth) showed improvement in progression-free survival (PFS) and overall survival (OS) in patients with platinum-resistant or platinum-refractory ovarian cancer ( 11 ). (frontiersin.org)
  • Ganetespib, a highly potent, small-molecule Heatshock protein 90 inhibitor, has potential efficacy in malignant pleural mesothelioma (MPM) via activity on critical survival pathways and known synergies with antifolates and platinum chemotherapy. (aacrjournals.org)
  • Increase survival in patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Subsyndrome of Acute Radiation Syndrome). (drugs.com)
  • Despite an often short and poor overall survival, there is marked heterogeneity in the duration of survival among patients. (biomedcentral.com)
  • These observed differences in care are concerning in their own right, but they may also contribute to the worse survival outcomes that have been reported among Black patients with gastrointestinal tract cancer. (medpagetoday.com)
  • Overall survival is typically poor, and less than 14% of patients survive longer than 5 years. (cancernetwork.com)
  • The press information stated that, "The study, which found that the addition of the innovative heat technique more than doubled the proportion of patients whose tumours responded to chemotherapy without increasing toxicity, is also the first to show that any treatment other than surgery followed by radiation can prolong survival of this type of patient. (news-medical.net)
  • Median survival was more than five years (62 months) for patients in the IP group and about four years (51 months) for patients in the IV group. (sciencedaily.com)
  • Markus Moehler, MD , Head of Gastrointestinal Oncology at Johannes Gutenberg-University Clinic, Mainz, Germany, reported that in the phase III RATIONALE 305 trial, tislelizumab (which is being developed in China) plus chemotherapy provided "a statistically significant and clinically meaningful improvement" in overall survival in patients with advanced PD-L1-positive gastric or gastroesophageal junction adenocarcinoma. (ascopost.com)
  • The overall survival benefit with tislelizumab plus chemotherapy was accompanied by improvements in progression-free survival, objective response rate, and duration of response. (ascopost.com)
  • The primary endpoint was overall survival in the 457 patients who were PD-L1-positive (PD-L1 score ≥ 5% of tumor cells), with hierarchical testing of the intention-to-treat population. (ascopost.com)
  • Progression-free survival and overall survival outcomes were analyzed in patients with (m) or without functional mutations in KRAS, STK11 or KEAP1. (ecancer.org)
  • Overall survival hazard ratios favoured patients in the tremelimumab, durvalumab and chemotherapy arm versus chemotherapy, irrespective of KRAS, STK11 or KEAP1 mutational status, consistent with results in the intent-to-treat population. (ecancer.org)
  • The median survival time in treated patients was 18 months. (lu.se)
  • Perioperative chemotherapy (adjuvant ou neoadjuvant) has been developed in order to improve these results. (bcan.org)
  • Despite maximal cytoreduction at the time of primary surgery and platinum-based adjuvant chemotherapy, 70-80% of patients with advanced ovarian cancer will relapse ( 4 ). (frontiersin.org)
  • The US Food and Drug Administration (FDA) approved pembrolizumab (Keytruda) in the adjuvant setting for patients with stage IB-IIIA non-small cell lung cancer (NSCLC) following resection and platinum-based chemotherapy. (medscape.com)
  • Among the 1010 patients who received adjuvant platinum-based chemotherapy, the median DFS was 58.7 months in the pembrolizumab arm (n = 506) and 34.9 months in the placebo arm (hazard ratio, 0.73). (medscape.com)
  • In an exploratory subgroup analysis of the 167 patients who did not receive adjuvant chemotherapy, the DFS hazard ratio was 1.25. (medscape.com)
  • analyzing the velocity (i.e., the change over time) of the markers, malignancy we could stipulate for each patient the risk of developing metas- tasis after the end of adjuvant systemic therapy. (lu.se)
  • The impact of therapeutic drug management (TDM) on reducing toxicity and improving efficacy in colorectal cancer (CRC) patients receiving fluorouracil-based chemotherapy is still unclear. (medscimonit.com)
  • TDM in colorectal cancer can reduce toxicity, improve efficacy and clinical outcome, and can be routinely used in 5-FU-based chemotherapy. (medscimonit.com)
  • The rest either died of cancer and/or chemotherapy-related toxicity, or they remained alive with cancer. (naturalnews.com)
  • The following data were collected: age, hormone and epidermal growth factor receptor 2 (HER-2) status, number of lines of chemotherapy prior to and after low-dose metronomic treatment, duration of metronomic treatment, toxicity reason for treatment discontinuation. (scirp.org)
  • Although the PCb combination achieved lower toxicity, patients treated with GC showed a trend toward a slightly higher median time to progressive disease (ie, a 1-month improvement). (cancernetwork.com)
  • The aim of this clinical trial was to test the efficacy of propolis as a mouthwash in the reduction of chemotherapy induced oral mucositis (OM) in a single center. (nih.gov)
  • Commenting on the results of the research, Ravindran Kanesvaran, consultant medical oncologist and assistant professor, Duke-NUS Medical School, Singapore, said: "The link between depression and poor outcomes among these patients is significant and can be associated with the downregulation of brain derived neurotrophic factor. (sciencedaily.com)
  • Duration of low-dose metronomic chemotherapy was also correlated with the variables analyzed and treatment outcomes. (scirp.org)
  • In this trial, randomization will be stratified by a modification of their IPFSG category and we will prospectively evaluate whether or not actual outcomes vary by risk group in the appropriate manner (low risk patients have higher OS than high-risk group). (cincinnatichildrens.org)
  • Among various remedies used for minimizing the sufferings of PN, Low Light Laser Therapy (LLLT) has a great potential to be utilized for improving PN outcomes, the quality of life and compliance during chemotherapy. (nova.edu)
  • Identification of patients at a high individual risk for FN and its consequences may offer the potential for optimal chemotherapy delivery and patient outcomes. (jnccn.org)
  • and varicella-zoster virus) can result in adverse patient outcomes and cause illness among health-care workers. (cdc.gov)
  • In our prior studies of employment outcomes among breast cancer patients, we found that African American race and non-private insurance status were associated with diminished employment participation after early-stage breast cancer. (cdc.gov)
  • We examined factors associated with return to work over 2-year follow-up in a sample of African-American breast cancer patients participating in a randomized controlled trial of a cancer-information intervention's impact (vs. standard of care) on quality- of -life and treatment adherence outcomes. (cdc.gov)
  • Understanding how psychosocial health influences returning-to- work outcomes in breast cancer patients could be particularly powerful for developing new strategies to reduce racial disparities in the quality of breast cancer survivorship. (cdc.gov)
  • Patients must have histologically diagnosed high-grade (Grade 2 or 3) serous epithelial ovarian, fallopian tube, or primary peritoneal cancer with recurrent disease and must have been previously treated with chemotherapy and experienced a response lasting at least 6 months to first-line platinum based therapy. (stanford.edu)
  • When a patient with a cancer, such as early stage bowel cancer, is diagnosed, their tumours seem to be limited to the bowel with no evidence of spread to elsewhere in the body. (theconversation.com)
  • combining it with chemotherapy in other localised tumours such as those in the pancreas and rectum are ongoing. (news-medical.net)
  • Patient tumours were molecularly characterized via sequencing of tumour tissue DNA and/or circulating tumour DNA samples. (ecancer.org)
  • What about the 28 patients in the study who received high-dose chemotherapy along with autologous bone marrow transplants (ABMT) at some point during their treatment? (naturalnews.com)
  • Drugs used in chemotherapy, such as paclitaxel, ifosfamide, cisplatin, carboplatin, and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. (cincinnatichildrens.org)
  • Tislelizumab was combined with chemotherapy (capecitabine plus oxaliplatin [XELOX] or cisplatin plus fluorouracil) and compared with chemotherapy alone as first-line treatment. (ascopost.com)
  • The National Comprehensive Cancer Network said Wednesday, June 7, 2023, that nearly all the centers it surveyed in late May 2023 were dealing with shortages of the chemotherapies carboplatin and cisplatin. (fox2now.com)
  • Nineteen hospitals also reported cisplatin shortages, but all said they were able to maintain the treatments for existing patients. (fox2now.com)
  • Two (0.5%) patients and 32 (8.1%) patients had dose delayed due to febrile neutropenia and neutropenia, respectively. (hindawi.com)
  • Four (1.0%) patients and 32 (8.1%) patients had a dose changed due to febrile neutropenia and neutropenia, respectively. (hindawi.com)
  • Furthermore, they can lead to delays and dose reductions in chemotherapy treatment, thereby potentially compromising the efficacy of chemotherapy and, consequently, patient outcome [ 10 ]. (hindawi.com)
  • There is strong and consistent clinical evidence to show that granulocyte-colony stimulating factors (G-CSFs) reduce the risk of chemotherapy-induced neutropenia and therefore complicated neutropenia and can be used to maintain chemotherapy at the desired dose intensity or density and minimize delays in treatment [ 11 ]. (hindawi.com)
  • We conducted a dose-escalation study to identify the maximum tolerated dose (MTD) of ganetespib in patients with chemotherapy-naïve MPM. (aacrjournals.org)
  • This randomized phase III trial studies how well standard-dose combination chemotherapy works compared to high-dose combination chemotherapy and stem cell transplant in treating patients with germ cell tumors that have returned after a period of improvement or did not respond to treatment. (cincinnatichildrens.org)
  • It is not yet known whether high-dose combination chemotherapy and stem cell transplant are more effective than standard-dose combination chemotherapy in treating patients with refractory or relapsed germ cell tumors. (cincinnatichildrens.org)
  • Progression of the disease may occur earlier for some patients due to dose limitation and/or discontinuation of treatment owing to severity of the side effects. (nova.edu)
  • The myeloid growth factors such as granulocyte colony-stimulating factor (G-CSF) have been shown to reduce the risk of neutropenia complications while enabling safe and effective chemotherapy dose intensity. (jnccn.org)
  • Neutropenia and its complications represent the major dose-limiting toxicities associated with systemic cancer chemotherapy and is associated with considerable morbidity, mortality, and cost. (jnccn.org)
  • 2 - 6 The myeloid growth factors (MGFs), including granulocyte colony-stimulating factor (G-CSF), have been shown to decrease the risk of neutropenic complications, facilitating the safe delivery of planned chemotherapy dose intensity on schedule. (jnccn.org)
  • Results from the same test could also help scale the dose for the patients who do need chemotherapy, depending on their risk of cancer returning. (theconversation.com)
  • Some are no longer able to treat patients receiving carboplatin at the intended dose or schedule. (fox2now.com)
  • Among the cancer centers with shortages of carboplatin, more than a third said they were unable to treat all patients according to the intended dose and schedule. (fox2now.com)
  • Patients must not have received a transfusion (platelets or red blood cells) within 4 weeks of the first dose of study treatment. (stanford.edu)
  • Thus, considering poor prognosis of lung cancer patients, it is crucial to find prognosis markers to develop predictive therapeutic methods. (hindawi.com)
  • For other cancers, such as ovarian and pancreatic, other methods are used to determine whether chemotherapy is necessary. (theconversation.com)
  • The study showed that the composition of intestinal bacteria may predict which women will gain weight as a result of chemotherapy. (vigorcolumn.com)
  • Results: The median time on metronomic chemotherapy was 5.4 months. (scirp.org)
  • Niraparib combined with anlotinib achieved median PFS of 11 months, disease re-progression, and the patient was switched to niraparib combined with letrozole from October 2021. (frontiersin.org)
  • Women who receive the treatment in the form of intraperitoneal, or IP chemotherapy are 17 percent more likely to survive longer than those who have IV chemotherapy, according to the analysis, which had a median follow-up of more than 10 years. (sciencedaily.com)
  • The median follow-up for patients in arm 1 was 3.77 years (range 0.19 to 5.23 years), and the median follow-up for patients in arm 2 was 3.97 years (range 0.44 to 5.15 years). (appliedradiationoncology.com)
  • A recent study suggests that patients with advanced ovarian cancer who undergo intensive treatment with chemotherapy that bathes the abdomen are significantly more likely to live longer than those who receive standard intravenous (IV) chemotherapy. (sciencedaily.com)
  • Patients with advanced ovarian cancer who undergo intensive treatment with chemotherapy that bathes the abdomen are significantly more likely to live longer than those who receive standard intravenous (IV) chemotherapy, according to a study that analyzed long-term follow-up from two landmark Gynecologic Oncology Group (GOG) trials comprising 876 patients. (sciencedaily.com)
  • The patient had recurrence of platinum resistance after secondary cytoreductive surgery, and it was difficult to continue chemotherapy after multiple lines of chemotherapy due to myelosuppression, renal impairment and other factors. (frontiersin.org)
  • It may also be given in combination with chemotherapy. (brainstrust.org.uk)
  • In April 2021, the U.S. Food and Drug Administration (FDA) approved nivolumab for use in combination with chemotherapy in the front-line treatment of advanced gastric or gastroesophageal junction cancer, based on the initial findings of CheckMate 649. (ascopost.com)
  • However, acral erythema due to tyrosine kinase inhibitors seems to differ somewhat from acral erythema due to classic chemotherapy drugs. (wikipedia.org)
  • ABSTRACT This descriptive exploratory study was conducted to describe the health care needs and identify unmet needs of the caregivers of cancer patients in Jordan. (who.int)
  • In addition, updated results of the global phase III CheckMate 649 trial upheld the benefit seen for nivolumab plus chemotherapy, according to Yelena Janjigian, MD , Chief of the Gastrointestinal Oncology Service at Memorial Sloan Kettering Cancer Center, New York. (ascopost.com)
  • These data, in conjunction with the safety data, continue to support the use of nivolumab plus chemotherapy in the first-line setting [in this population]. (ascopost.com)
  • Patients were randomly assigned to receive either tislelizumab and chemotherapy or placebo plus chemotherapy. (ascopost.com)
  • A brain-boosting protein plays an important role in how well people respond to chemotherapy, researchers report, suggesting that depression may have an impact on a patient's response to chemotherapy. (sciencedaily.com)
  • The judicious use of these drugs could spare the burden of extra costs and the potential risk for adverse effects for patients. (urotoday.com)
  • A total of 68 patients (17.3%) were reported to have experienced at least one grade 3-4 adverse event during the study. (hindawi.com)
  • No significant adverse events were reported by the patients. (nih.gov)
  • Our objective is to identify the most effective interventions that mitigate the risk of adverse cardiac events associated with serotonin receptor antagonists in patients undergoing surgery and chemotherapy through a systematic review and network meta-analysis. (biomedcentral.com)
  • Adverse reactions were largely similar to those observed in patients with NSCLC who receive pembrolizumab as a single agent. (medscape.com)
  • How to reduce intravenous chemotherapy-related adverse reactions of cancer patients is one focus of clinical work. (oncotarget.com)
  • Nowadays, patient for patient safety (PFPS) is an important component of hospital safety management and can contribute to a reduction in the rate of adverse events following intravenous chemotherapy of cancer patients. (oncotarget.com)
  • Based on a literature review and analysis of chemotherapy-associated adverse events from two large comprehensive hospitals, combined with the existing strategies for PFPS, the model of cancer patients participation in intravenous chemotherapy safety was drafted. (oncotarget.com)
  • We have shown for the first time that the pre-treatment microbiome of patients that gained weight following chemotherapy is different than the microbiome of patients that did not gain weight and that faecal transplantation from patients that gained weight results in glucose intolerance, adverse lipid changes and inflammatory changes in germ-free mice," said Prof Koren. (vigorcolumn.com)
  • The most common EGFR mutations (nearly 85%-90%) in NSCLC patients are L858R and exon 19 deletions (Ex19del), which are defined as classical mutations. (frontiersin.org)
  • EGFR G724S mutation in exon 18 is a rare driver mutation, only found in about 0.3%-0.8% of NSCLC patients. (frontiersin.org)
  • This article briefly summarizes thecurrent evidence that supports the role of pemetrexed-based combinationsin clinical trials for chemonaive patients with advanced NSCLC. (cancernetwork.com)
  • 1.Patient has a histologically or cytologically confirmed diagnosis of non-small cell lung cancer (NSCLC) that is anaplastic lymphoma kinase (ALK) positive as assessed by the FDA approved Abbott FISH Test. (who.int)
  • The cost of care for patients receiving chemotherapy was consistently lower in the community oncology clinic compared with the hospital outpatient setting, controlling for the clinical, demographic, and geographic variables analyzed. (ajmc.com)
  • Olbert PJ, Hegele A, Kraeuter P et al (2006) Clinical significance of a prostate-specific antigen flare phenomenon in patients with hormone-refractory prostate cancer receiving docetaxel. (springer.com)
  • Besides clinical factors of age, sex, smoking stage, histology, and grade, many genetic polymorphisms also were considered correlation with prognosis in cancer patients. (hindawi.com)
  • A 1994 study published in the Journal of Clinical Oncology reveals a shocking truth about chemotherapy that the cancer industry refuses to acknowledge. (naturalnews.com)
  • Eastern Cooperative Oncology Group performance status (ECOG PS), C-reactive protein (CRP), albumin, Glasgow prognostic score (GPS), and clinical factors were recorded immediately prior to first-line chemotherapy. (biomedcentral.com)
  • Clinical factors such as liver metastasis, carcinomatosis peritonei, and bone metastasis are easily identifiable and imply that a patient has an advanced cancer. (biomedcentral.com)
  • The problem can also arise in patients after bone marrow transplants, as the clinical and histologic features of PPE can be similar to cutaneous manifestations of acute (first three weeks) graft-versus-host disease. (wikipedia.org)
  • Concerns about the high costs of these agents along with limited physician adherence to clinical practice guidelines, resulting in both overuse and underuse, has stimulated interest in models for individual patient risk assessment to guide appropriate use of G-CSF. (jnccn.org)
  • The risk of FN in patients receiving systemic chemotherapy has generally been based on the rates of FN in patients eligible for randomized controlled clinical trials (RCTs). (jnccn.org)
  • The current AI algorithm might guide an individualized treatment strategy including nonsurgical approach in ESCC patients through prospective studies with careful external validation to demonstrate the clinical value of this diagnostic approach including primary tumor and lymph node . (bvsalud.org)
  • The goal of this clinical trial is to compare the effectiveness of unseparated whole blood (referred to as Low-Titer Group O Whole Blood) and the separate components of whole blood (including red cells, plasma, platelets, and cryoprecipitate) in critically injured patients who require large-volume blood transfusions. (nih.gov)
  • The risk of distant recurrence in breast cancer patients is difficult to prognostic indices, such as the Nottingham Prognostic Index (6, 7), assess with current clinical and histopathological parameters, and have proven valuable in identifying patients with poor prognosis. (lu.se)
  • Initial management consisted of en una paciente con topical corticosteroids and oral antihistamines with little clinical response. (bvsalud.org)
  • To describe the pattern in Japan of overprescribing prophylactic antiemetic drugs to patients who have received intravenous chemotherapy with minimal or low emetic risk. (urotoday.com)
  • and (3) received intravenous chemotherapy with minimal or low emetic risk. (urotoday.com)
  • To guide and evaluate cancer patients participate in intravenous chemotherapy, we explored a scientific and practical model of cancer patients participation in intravenous chemotherapy safety. (oncotarget.com)
  • The model of cancer patients participation in intravenous chemotherapy safety can guide NPs in their practice of promoting PFPS among cancer patients intravenous chemotherapy. (oncotarget.com)
  • 21, 2022 Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation and chemotherapy. (sciencedaily.com)
  • Tumors in the lung may be treated with surgery, radiation, chemotherapy, targeted therapy, or combinations of these approaches. (cancercare.org)
  • All patients received preoperative pelvic radiation therapy of 50.4 Gy over five-and-a-half weeks, with 45 Gy delivered in 25 fractions (1.8 Gy per fraction, five fractions per week for five weeks) and a boost of 5.4 Gy in three fractions. (appliedradiationoncology.com)
  • Patients were randomized to two chemotherapy treatment arms concurrent to their radiation therapy: Patients in arm 1 received concurrent chemotherapy consisting of four doses of irinotecan (50 mg/m2 IV weekly) and capecitabine (1200 mg/m2/d orally Monday through Friday during radiation therapy). (appliedradiationoncology.com)
  • Patients in arm 2 received concurrent chemotherapy consisting of five doses of oxaliplatin (50 mg/m2 IV weekly) and capecitabine (1600 mg/m2/d orally Monday through Friday during radiation therapy). (appliedradiationoncology.com)
  • All patients in each arm had surgery four to six weeks after completion of radiation therapy, and all patients in both arms had postoperative chemotherapy of FOLFOX four to six weeks after surgery. (appliedradiationoncology.com)
  • Patient evaluations occurred weekly during concurrent chemotherapy and radiation therapy, before surgery and before each cycle of postoperative chemotherapy. (appliedradiationoncology.com)
  • Some people with cancer will have only one treatment, but most people will have what is called combination treatment, such as surgery with chemotherapy and/or radiation therapy. (mountsinai.on.ca)
  • Patients at Sinai Health are generally referred to Princess Margaret Cancer Centre or a local centre for radiation. (mountsinai.on.ca)
  • Conclusions: Oral abnormalities were common in children receiving chemotherapy and mucositis was the most prevalent manifestation. (bvsalud.org)
  • Conclusions: Patients with elevated depressed mood were less likely to return to work over 2-year follow-up. (cdc.gov)
  • In general , it provides better tolerance, especially in patients who have been previously exposed to other oncologic treatments, with a favorable cost-effectiveness profile. (scirp.org)
  • On the other hand, in order to provide our patients with the opportunity of receiving many treatment lines with sustained or improved quality of life, we must be able to develop better supportive measure strategies as well as less toxic treatments. (scirp.org)
  • FILE - In this May 25, 2017 file photo, chemotherapy drugs are administered to a patient at a hospital in Chapel Hill, N.C. A growing shortage of common cancer treatments is forcing doctors to switch medications and delaying care, prominent U.S. cancer centers say. (fox2now.com)
  • Dr. Kari Wisinski has had to turn to other treatments for some patients or switch the order in which people receive their drug combinations. (fox2now.com)
  • These concerns may affect patients during or after cancer treatments. (cdc.gov)
  • Pemetrexed was one of the chemotherapy treatments. (who.int)
  • Of these, patients who received 24 373 administrations of chemotherapy with a low emetic risk (47.8%) and 633 administrations of chemotherapy with a minimal emetic risk (2.8%) were prescribed serotonin receptor antagonists and dexamethasone. (urotoday.com)
  • To increase their quality of life and treatment satisfaction, antiemetic medication, such as serotonin receptor antagonists, is often prescribed for patients experiencing these symptoms. (biomedcentral.com)
  • We will search electronic databases (for example, MEDLINE, Embase) from inception onwards, as well as dissertations and governmental reports, to identify interventions (for example, telemetry, electrocardiography, electrolyte monitoring) that decrease the cardiac risk associated with serotonin receptor antagonists among surgery and chemotherapy patients. (biomedcentral.com)
  • The Phase III study involved 341 patients who were treated at medical centers in Europe and in the United States. (news-medical.net)
  • I believe that the cancer centers should refer patients for psychological evaluations post diagnosis. (cdc.gov)
  • There is increasing evidence that the presence of an ongoing systemic inflammatory response is associated with poor prognosis in patients with advanced cancers. (biomedcentral.com)
  • The cost of care for patients receiving chemotherapy in community oncology clinics is lower than for comparable patients receiving chemotherapy in the hospital outpatient setting. (ajmc.com)
  • and 2) various cancer care-related cost categories between patients receiving chemotherapy in a community oncology versus a hospital outpatient setting. (ajmc.com)
  • These patients were assigned to cohorts depending on whether they received chemotherapy at a community oncology or hospital outpatient setting. (ajmc.com)
  • Community oncology and hospital outpatient setting chemotherapy treatment costs were categorized and examined according to cancer diagnosis, patient demographics, and geographic location. (ajmc.com)
  • Patients receiving chemotherapy treatment in the community oncology clinic had a 20% to 39% lower mean per member per month cost of care, depending on diagnosis, compared with those receiving chemotherapy in the hospital outpatient setting. (ajmc.com)
  • A total of 82 caregivers accompanying patients to an outpatient chemotherapy clinic completed the 90-item caregiver need scale. (who.int)
  • There is a growing interest in shortening hospital stays for patients with cancer and treating them on an outpatient basis [1-3]. (who.int)
  • Alcaligenes xylosoxidans Bloodstream Infections cultures reported from both laboratories) were associated healthcare workers who accessed CVCs, collected blood, with a single outpatient oncology offi ce, Offi ce B. The oth- prepared fl ushes, or administered chemotherapy. (cdc.gov)
  • A retrospective study reported AKI in 40.4% of patients ( 8 ). (frontiersin.org)
  • In those undergoing curative surgery for gastrointestinal (GI) tract cancers, Black patients were less likely to receive standard of care treatment, a large retrospective study found. (medpagetoday.com)
  • Peripheral neuropathy (PN) affects 40% of all patients who receive chemotherapy for any reason that can lead to discontinuation of drug treatment. (nova.edu)
  • 3.Patient has at least one measurable lesion as defined by RECIST 1.1. (who.int)
  • The purpose of this study is to examine the effectiveness of acupressure in regards to the Quality of Sleep of Head and Neck Cancer Patients receiving Chemotherapy. (confex.com)
  • 5) receiving Chemotherapy from the Head and Neck Cancer units of a medical center in Southern Taiwan. (confex.com)
  • Results: Acupressure significantly improved the quality of daily sleep, as well as the sleep quality in the previous one month of Head and Neck cancer patients receiving chemotherapy. (confex.com)
  • This study serves as a reference for medical practitioners to help improve sleep quality of Head and Neck cancer patients receiving chemotherapy. (confex.com)
  • Among 73 patients treated for a type of testicular cancer marked by relapsed extragonadal nonseminomatous germ cell tumors (GCTs) at Indiana University between 1976 and 1993, only five survived. (naturalnews.com)
  • She reported that at 3 years, this treatment resulted in a 30% reduction in the risk of death over chemotherapy alone in patients with tumors enriched for PD-L1 expression. (ascopost.com)
  • no patients' tumors are exactly the same. (cancercare.org)
  • 9, 2020 Researchers showed that a protein named FOXO1 plays a critical role in heart damage resulting from treatment with anthracycline chemotherapy drugs. (sciencedaily.com)
  • But after a successful surgery to remove the bowel cancer, around one-third of these patients will experience cancer recurrence elsewhere in the body in the following years. (theconversation.com)
  • Ultimately, some high-risk patients will not have cancer recurrence because their cancer has been cured by surgery alone, while other apparently low-risk patients will suffer from recurrence. (theconversation.com)
  • All patients had locally advanced soft tissue sarcomas and were at high risk of recurrence and spread. (news-medical.net)
  • Almost three years after starting treatment, they were 42% less likely to experience a recurrence of their cancer at the same site or to die than those who were getting chemotherapy alone, surviving an estimated 120 months before local progression of their disease, compared with an estimated 75 months. (news-medical.net)
  • The use of antiemetic drugs for patients receiving chemotherapy with low or minimal emetic risk has been recognized as a growing concern for health care costs and patients' welfare. (urotoday.com)
  • The percentage of chemotherapy administration involving patients prescribed prophylactic antiemetic drugs, namely, a neurokinin 1 receptor antagonist, serotonin receptor antagonist, and/or dexamethasone, was calculated. (urotoday.com)
  • Consequently, approximately ¥170 million (US $1.6 million) was unnecessarily spent on prophylactic antiemetic drugs for these patients. (urotoday.com)
  • A substantial number of patients receiving chemotherapy with minimal and low emetic risk were prescribed potentially unnecessary prophylactic antiemetic drugs. (urotoday.com)
  • Our aim now is to prescribe drugs such as fluoxetine to depressed patients and study their sensitivity to chemotherapy," added Wu. (sciencedaily.com)
  • Now, a research team headed by Professor Alexander Binshtok, head of the Pain Plasticity Research Group at the Hebrew University of Jerusalem's Faculty of Medicine and Edmond & Lily Safra Center for Brain Sciences, has developed a method that delivers chemotherapy drugs directly to malignant cells and bypasses healthy ones. (israelnationalnews.com)
  • Decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia. (drugs.com)
  • Chemotherapy is a treatment which uses drugs to treat cancer cells. (brainstrust.org.uk)
  • Anti-myeloma drugs such as bortezomib (BTZ) and thalidomide, despite being expedient targeted therapeutics, are typically implicated as primary causes of PN in MM patients. (nova.edu)
  • Surveys have shown that many patients and their loved ones believe nausea and vomiting occur with all types of chemotherapy (anti-cancer drugs). (cancercare.org)
  • In reality, half of the chemotherapy drugs now in use became available in the past several years, and their side effects are not necessarily the same as those caused by older drugs. (cancercare.org)
  • That's especially crucial if you are receiving chemotherapy in pill form, as you will need to take the chemotherapy and the anti-nausea drugs in a certain order and at a certain time of day. (cancercare.org)
  • In standard IV chemotherapy, the drugs are infused into the bloodstream and throughout the body, whereas IP treatment directs the chemotherapy to the abdomen. (sciencedaily.com)
  • This not only places a high concentration of cancer-killing drugs where they are needed, but the chemotherapy agents are absorbed more slowly, providing more exposure to the medicine. (sciencedaily.com)
  • Two phase III trials evaluating the addition of drugs targeting PD-1 to chemotherapy-RATIONALE 305 and CheckMate 649-confirmed the benefit of this approach as first-line therapy for advanced gastric, gastroesophageal junction, or esophageal adenocarcinoma, in findings presented at the 2023 ASCO GI Cancers Symposium. (ascopost.com)
  • Chemotherapy (chemo) is the use of drugs to treat cancer. (cancer.org)
  • Chemotherapy involves using medicine (special cancer drugs) to kill or slow the growth of cancer cells. (mountsinai.on.ca)
  • 2.Patient with a history of severe hypersensitivity reaction to pemetrexed or docetaxel or any known excipients of these drugs. (who.int)
  • We reviewed 402 patients with advanced gastric adenocarcinoma who received first-line palliative chemotherapy from June 2004 and December 2009. (biomedcentral.com)
  • As time progresses, patients with graft-versus-host disease progress to have other body parts affected, while PPE is limited to hands and feet. (wikipedia.org)
  • Among more than half a million such patients, lower odds of negative surgical margins (odds ratio [OR] 0.96, 95% CI 0.93-0.98) and adequate lymphadenectomy (OR 0.89, 95% CI 0.87-0.91) were observed for Black versus white patients, according to Sajid Khan, MD, of the Yale School of Medicine in New Haven, Connecticut, and colleagues. (medpagetoday.com)
  • RTOG 0247 was a randomized, Phase II multicenter trial of patients with locally advanced (T3 and T4) rectal cancer treated with neoadjuvant chemoradiation from March 2004 to February 2007. (appliedradiationoncology.com)
  • A study reported acute kidney injury (AKI) in 10880 patients of 163,071 patients on systemic therapy for cancer with an cumulative incidence of 9.3% ( 7 ). (frontiersin.org)
  • Patients must agree to undergo tumor HRD testing and blood gBRCAmut status testing. (stanford.edu)
  • Patients must have formalin-fixed, paraffin-embedded tumor samples available from the primary or recurrent cancer or agree to undergo fresh biopsy prior to study treatment initiation. (stanford.edu)
  • before resection of the primary tumor and then postoperatively every 6-12 mo, resulting in three to five samples per patient. (lu.se)
  • However, we found a rare mutation of EGFR Ex19del/G724S in two patients with lung cancer who demonstrated a favorable response to the combination of afatinib and chemotherapy. (frontiersin.org)
  • In this study, we reported two patients with EGFR Ex19del/G724S lung cancer who appeared in remission after being treated with afatinib and chemotherapy. (frontiersin.org)
  • Plasma or cerebrospinal fluid samples of these patients were then sequenced after treatment using a 139-lung-cancer-gene capture-based targeted panel (Geneseeq), aiming to comprehensively profile their concurrent mutation statuses and explore the potential resistance mechanisms in G724S-positive patients. (frontiersin.org)
  • A 47-year-old Chinese female patient without a smoking history was preliminarily diagnosed with right lung cancer with suspected multiple liver and bone metastasis. (frontiersin.org)
  • In this study, we focus on evaluating association between DNA repair polymorphisms of EXO1, RPA1, and prognosis in lung cancer patients whom received platinum-based chemotherapy. (hindawi.com)
  • 593 lung cancer patients were recruited in this study. (hindawi.com)
  • Rs1776148, rs1047840, and rs5030740 may act as prognosis markers in lung cancer patients with platinum-based chemotherapy. (hindawi.com)
  • And platinum-based chemotherapy still acted as the first-line treatment for lung cancer patients. (hindawi.com)
  • Acute respiratory distress syndrome (ARDS): Evaluate patients who develop fever, lung infiltrates, or respiratory distress. (drugs.com)
  • Insufficient up-regulation of IL-10 in the lung may fuel persistent local inflammation thereby promoting lung pathology in TB-DM patients with poorly controlled DM. (biomedcentral.com)
  • The drug bevacizumab (Avastin), while helpful in individuals with adenocarcinomas, can cause severe side effects in patients with squamous cell lung cancers. (cancercare.org)
  • In the past, patients with the same type and stage of lung cancer received the same treatment. (cancercare.org)
  • Proteomic testing A new blood test called VeriStrat is available for advanced non-small cell lung cancer patients. (cancercare.org)
  • The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. (nih.gov)
  • The intention of this study is to describe the impact and underlying potential basis of the prostate-specific antigen (PSA) flare-up phenomenon in patients with hormone-refractory prostate cancer (HRPC) treated with docetaxel-based chemotherapy. (springer.com)
  • We retrospectively identified 74 consecutive patients who received docetaxel/estramustine-based chemotherapy at our institution. (springer.com)
  • Patients in this arm received chemotherapy of either pemetrexed or docetaxel as determined by BIRC. (who.int)
  • In 2000, two articles reporting the first rationale of chemotherapy in low doses were published. (scirp.org)
  • This discovery could allow doctors to reduce chemo doses for patients, thereby reducing the unpleasant side-effects associated with the treatment, and improve treatment compliance and overall prognoses. (israelnationalnews.com)
  • In the future, the precision of this delivery method may allow doctors to prescribe lower chemo doses and to relieve patients from some of the harsher effects of chemo. (israelnationalnews.com)
  • 3.Patient with symptomatic central nervous system (CNS) metastases who is neurologically unstable or has required increasing doses of steroids within the 2 weeks prior to screening to manage CNS symptoms. (who.int)
  • Cost differential was consistent across diagnosis, geography, patient age, and number of chemotherapy sessions. (ajmc.com)
  • It is a feeling that many who receive a cancer diagnosis can identify with: heartbreak and fear, followed by hopes that chemotherapy will save the day. (israelnationalnews.com)
  • NOTE: In rare circumstances, patients will be allowed to enroll even if a pathologic diagnosis may not have been established. (cincinnatichildrens.org)
  • Painful red swelling of the hands and feet in a patient receiving chemotherapy is usually enough to make the diagnosis. (wikipedia.org)
  • If this was not bad enough, these inequalities may be an underestimation of the true disparities, given that Black patients are less likely to receive any diagnosis or treatment. (medpagetoday.com)
  • Even when Black patients overcome barriers to their diagnosis and treatment (e.g., mistrust in the health care system) and accept adjunct therapies such as chemotherapy, they still may receive substandard treatment," they wrote. (medpagetoday.com)
  • With advances in detection and treatment, the population of breast cancer survivors is expected to increase by 25% to almost 4 million by the year 2024, and approximately nine out of every ten breast cancer patients are expected to live at least five years after diagnosis. (cdc.gov)
  • Screening for depressed mood at diagnosis and providing treatment might be an effective strategy to improve continued work force participation in African American breast cancer patients. (cdc.gov)
  • During 2010, the data set contained approximately 45 million unique commercially insured patients with 70,984 cancer patients receiving chemotherapy. (ajmc.com)
  • The education and support needs of caregivers need to be considered when designing care plans for cancer patients. (who.int)
  • Noguchi K, Uemura H, Harada M et al (2001) Inhibition of PSA flare in prostate cancer patients by administration of flutamide for 2 weeks before initiation of treatment with slow-releasing LH-RH agonist. (springer.com)
  • found that high expression level of the EXO1 is associated with poor OS in breast and prostate cancer patients [ 26 , 27 ]. (hindawi.com)
  • Why don't oncologists refund cancer patients when their chemotherapy fails? (naturalnews.com)
  • Despite this, the cancer industry would have us all believe that it's the only tried-and-true lifeline for cancer patients. (naturalnews.com)
  • Multiply this out by the total number of cancer patients in the developed world and you'll quickly see why this exceptionally profitable, multi-billion dollar cash cow is never questioned or reevaluated in terms of its safety and effectiveness. (naturalnews.com)
  • Five or more years of tamoxifen use increases risk of cataracts in breast cancer patients. (greenmedinfo.com)
  • Tamoxifen interferes with cognitive function in breast cancer patients. (greenmedinfo.com)
  • A study has found that cancer patients suffering depression have decreased amounts of brain-derived neurotophic factor (BDNF) in their blood. (sciencedaily.com)
  • Low mood is common among cancer patients, especially the terminally ill. (sciencedaily.com)
  • Although the exact mechanism by which systemic inflammation arises in cancer patients remains to be clarified, it is generally accepted that cancer associated inflammation is modulated by cancer cells, host stromal cells, and their interactions [ 7 ]. (biomedcentral.com)
  • Thus, chemotherapy induced PN (CIPN) can be severe and debilitating, eventually impacting quality of life in cancer patients. (nova.edu)
  • Many cancer patients have chemotherapy after surgery, but not all of them actually need it. (theconversation.com)
  • Many cancer patients could soon be spared the unnecessary side effects of chemotherapy after having surgery to remove their tumour. (theconversation.com)
  • So, early stage cancer patients often receive chemotherapy after surgical treatment as a precaution - to mop up any cancer cells that could remain. (theconversation.com)
  • Current trials in early-stage bowel cancer patients started in 2015. (theconversation.com)
  • So, many bowel cancer patients are currently treated with six months of chemotherapy and its associated side effects, even though they do not need to be treated. (theconversation.com)
  • They said their goal was to provide an update on how GI tract cancer patients have fared since the time of the report's release. (medpagetoday.com)
  • There is no question IP therapy should be much more widely offered, and advanced ovarian cancer patients should consult with gynecologic oncologists or medical oncologists with experience in this cancer who have the expertise to determine the best therapy," said Dr. Tewari. (sciencedaily.com)
  • The proposed safety model included 3 first-order indicators, 8 second-order indicators, and 41 third-order indicators, including content of patients participation, responsibilities of medical personnel to assist cancer patients participation, and suggestions for guaranteeing implementation. (oncotarget.com)
  • Many NPs practice in a medical setting where cancer patients for patient safety behavior are blurred. (oncotarget.com)
  • The samples were collected from breast cancer patients rent procedures. (lu.se)
  • It is our expectation that we will integrate findings from this study to establish criteria for identifying and engaging breast cancer patients who are at high risk for leaving to work force and, based on such findings, develop an empirically-grounded strategy for improving return-to- work in breast cancer patients. (cdc.gov)
  • Your oncology care providers now have many ways to prevent and ease nausea and vomiting from chemotherapy. (cancercare.org)
  • Others don't feel symptoms the day of chemotherapy but develop nausea and vomiting during the following few days (a delayed reaction). (cancercare.org)
  • Patients in the VC arm experienced grade 3/4 hematologic toxicities, specifically leukopenia ( P = .002) and neutropenia ( P = .008) and grade 3 nausea ( P = .001) and vomiting ( P = .007) at significantly higher frequencies than patients receiving PCb. (cancernetwork.com)