Patients procedure autologous transplantation. Medical search. Frequent questions

When the donor is someone other than the recipient, the procedure is described as allogeneic transplantation. (medscape.com)
Allogeneic transplantation is also used for the management of certain genetic abnormalities. (medscape.com)
The three main categories of allogeneic transplantation are HLA identical, HLA mismatched, and haploidentical. (medscape.com)
The procedure involves the transplantation of cells taken either from a patient's own blood or bone marrow (autologous transplantation) or from a matched donor (allogeneic transplantation) which effectively "replaces" damaged cells with healthy cells. (science20.com)
The early transplantation cohort had a median time from diagnosis to transplantation of 7 months in autologous transplantation recipients and 9 months in allogeneic transplantation recipients, compared with 19 and 30 months in the late transplantation cohort. (ascopost.com)
Within the early and late cohorts, the autologous and allogeneic transplantation groups were similar with regard to number of prior lines of chemotherapy and disease status before transplantation. (ascopost.com)
Five-year overall survival was similar for the autologous vs the allogeneic transplantation groups in the early cohort (61% vs 62%, P = .951) and in the late cohort (44% vs 31%, P = .202). (ascopost.com)
Survival was significantly better in patients in the early cohort among both autologous ( P = .004) and allogeneic transplantation patients ( P = .005). (ascopost.com)
In the reduced-intensity conditioning allogeneic transplantation group, early transplantation was associated with higher mortality within 2 years (RR = 2.34, P = .017) but lower mortality after 2 years (RR = 0.31, P = .017). (ascopost.com)
For allogeneic transplantation, the patient receives bone marrow or stem cells from a donor who may or may not be a relative. (ucsfhealth.org)

The aim of this study is to evaluate the prognostic impact of myeloid-derived suppressor cells (MDSCs) in multiple myeloma (MM) in the context of autologous stem cell transplantation (ASCT). (biomedcentral.com)
Both MDSC phenotypes pre-ASCT but not post-ASCT similarly suppressed in vitro autologous T and natural killer T cell proliferation. (biomedcentral.com)
During the COVID-19 outbreak, planned autologous stem cell transplant (ASCT) for patients may be postponed to a more suitable time. (mpeurope.org)
High-dose therapy (usually high-dose melphalan), and the ASCT procedure itself, weaken the immune system and potentially make myeloma and AL amyloidosis patients more susceptible and less able to fight infections like COVID-19. (mpeurope.org)
Patients who undergo ASCT also need to regularly attend hospital appointments for monitoring, increasing the risk of COVID-19 transmission through social interactions. (mpeurope.org)
The decision about whether an ASCT will proceed during this time can only be made between a patient and their doctor. (mpeurope.org)
The ability of a hospital to effectively isolate patients undergoing ASCT. (mpeurope.org)
As with all treatment decisions during the COVID-19 outbreak, the benefits and risks of a patient undergoing ASCT must be balanced. (mpeurope.org)
In most European countries, ASCT is taking place only where it is considered the best and most appropriate course of action for a patient. (mpeurope.org)
Treatment selection takes into account patient age, fitness, and whether autologous stem cell transplantation (ASCT) is planned. (medscape.com)

Autologous chondrocyte transplantation (Carticel) was first performed to treat patellar defects in rabbits in 1984. (drlintner.com)

The transplant procedure requires the harvesting of hematopoietic stem cells from a donor. (medscape.com)
In autologous transplantation, the donor and recipient is the same individual. (medscape.com)
2 These cells either originate from the patient (autologous) or a donor (allogeneic). (pharmaceuticalcommerce.com)
The only curative option for end-stage cirrhosis is liver transplantation but donor organ availability cannot meet demand and many patients die waiting for a suitable organ. (ukri.org)
In this type of transplant, stem cells are taken from a donor (usually a close relative or sibling) and given to the patient. (vanyahealth.com)
Both haploidentical BMT and cord blood transplant are considered alternative options for patients who do not have a suitable matched donor. (vanyahealth.com)
Bone marrow transplants work best if the HLAs from the donor and the patient are a close match. (medlineplus.gov)
This means the donor will be asleep and pain-free during the procedure. (medlineplus.gov)

The present report describes an incomplete atypical femoral fracture (AFF) patient who underwent simultaneous autogenous bone transplantation to the resected fracture region during intramedullary nail fixation. (hindawi.com)
To the best of our knowledge, this is the first report in which autogenous bone marrow transplantation, noninvasive to the iliac crest, was performed in an incomplete AFF patient. (hindawi.com)
The present report shows a minimally invasive procedure, which could facilitate bone union in incomplete AFF. (hindawi.com)
Autologous transplantation is feasible when the patient's bone marrow is normal and there are no relevant genetic conditions. (medscape.com)
We documented that incidence of zygomycosis increased, particularly in patients with hematologic malignancies or bone marrow transplants. (cdc.gov)
and finally, prolonged use of new antifungal drugs ineffective against zygomycetes as prophylactic or empiric treatment in bone marrow transplant recipients or other immunocompromised patients ( 10 , 17 - 20 ). (cdc.gov)
We focus on destroying only the immune component of the bone marrow and then regenerate the immune component, which makes the procedure much safer and less toxic than traditional chemotherapy for cancer," Burt said. (scienceblog.com)
They further say that this study is one of the longest and is the most inclusive to date evaluating sexual well-being in blood or bone marrow transplantation (stem cell transplantation, SCT) survivors using rigorous, well-validated sexual function assessment tools. (science20.com)
As blood or bone marrow transplantation survival rates have steadily increased, researchers are seeking to study and maximize survivors' quality of life. (science20.com)
Primary end points were reduction in insulin requirement by ≥50% and improvement in glucagon-stimulated C-peptide levels at the end of 6 months of autologous bone marrow-derived stem cell transplantation (SCT), while secondary end points were a change in weight and HbA1c and lipid levels as compared to baseline. (drcalapai.com)
The administration of bone marrow usually occurs after a patient has received high-dose chemotherapy or radiation. (ucsfhealth.org)
These are the important cells that are transferred during bone marrow or stem cell transplantation. (ucsfhealth.org)
When the stem cells are collected from the hip bone by performing many bone marrow aspirations (usually performed in the operating room), the transplant procedure is called a bone marrow transplant. (ucsfhealth.org)
Advances in the treatment of cancer and improvements in supportive care over the past 10 years have improved the results and tolerability of bone marrow transplantation. (ucsfhealth.org)
However, having a bone marrow transplant remains a dangerous and difficult procedure. (ucsfhealth.org)
For autologous transplantation, the patient receives his or her own bone marrow or stem cells that were collected and frozen before admission for high-dose chemotherapy or radiation. (ucsfhealth.org)
The procedure is based on an autologous bone-marrow transplant (when patients receive a transplant of their own stem cells) and now constitutes a treatment option to cure an intestinal disease that sometimes does not successfully respond to drugs and requires highly complex surgery that does not provide a cure. (sciencedaily.com)
Bone Marrow Transplantation (BMT) is a medical procedure that involves replacing damaged or diseased bone marrow with healthy bone marrow stem cells. (vanyahealth.com)
There are two main types of Bone Marrow Transplantation (BMT): autologous and allogeneic. (vanyahealth.com)
Patients who have had a bone marrow transplant are at an increased risk of infections due to the suppression of their immune system. (vanyahealth.com)
Insertion of central venous catheters in children undergoing bone marrow transplantation: is there a platelet level for a safe procedure? (springeropen.com)
Bone marrow transplantation (BMT) is a therapeutic procedure for the management of several hematological diseases and malignancies in pediatric population. (springeropen.com)
Bone marrow transplantation (BMT) is currently considered as a practiced and a well-established modality for the treatment of several hematological diseases and malignancies in children [ 1 ]. (springeropen.com)
Autologous bone marrow transplant is when people donate their own bone marrow. (medlineplus.gov)
Several drug therapies are valuable in the treatment of symptomatic MM. Clinicians treat many patients with high-dose therapy and peripheral blood or bone marrow stem cell transplantation. (medscape.com)

Thanks to improved transplant survival rates, we have now been able to focus our efforts on examining how the procedure affects key aspects of recipients' overall quality of life, including sexual health," said lead study author F. Lennie Wong, PhD, of City of Hope in Duarte, California. (science20.com)
There were no significant differences in 5-year overall survival for autologous vs reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation in the early transplantation cohort or in the late cohort. (ascopost.com)
They found no significant overall survival differences between procedures. (ascopost.com)
Survival was significantly better for both procedures when transplantation occurred earlier in the disease course. (ascopost.com)
Among autologous transplantation recipients, 5-year overall survival was 75% in patients with first complete response with one line of pretransplantation therapy, 70% in those with first complete response with two lines of therapy, and 38% in those with primary induction failure-sensitive disease (partial remission with no history of complete response). (ascopost.com)
On multivariate analysis of overall survival from the time of diagnosis, stem cell transplantation beyond first complete response, greater age (≥ 60 years), no rituximab prior to transplantation, and increased lactate dehydrogenase at diagnosis were associated with significantly inferior survival. (ascopost.com)
In the autologous transplantation group, survival was greater with early vs late transplantation (relative risk [RR] of death = 0.70, P = .037). (ascopost.com)
The survival of treated patients was statistically higher (P=0.01) than untreated control patients. (cellsurgicalnetwork.com)
This retrospective study analyzes progression-free survival and overall survival in patients who do not have a partial response (never responded or progressed during continuous therapy) after induction therapy with a regimen that contains thalidomide or lenalidomide. (elsevierpure.com)
Hematopoietic stem cell transplantation not responded to other therapeutic modalities, with (HSCT) is used in children as a definitive treatment an increase in survival after transplantation, for different oncological, immune deficiencies, contributing to its use (YEILIPEK, 2014). (bvsalud.org)
The benefits of human tissue transplantation can be seen in both children and adults, including in survival rates following severe burn trauma, recovery of movement, closure of chronic wounds, rehabilitation of heart function and restoration of sight. (who.int)
Kidney transplantation is a far more favourable treatment modality versus dialysis in terms of survival, quality of life and cost-effectiveness. (who.int)

Only the patient's own blood serum is used for the procedure. (joint-surgeon.com)

UK media recently reported that a Birmingham-based company called ProFaM (Protecting Fertility and Menopause) were offering a "new" procedure for women: cryopreservation of autologous ovarian tissue to delay menopause through later reimplantation. (imsociety.org)
It was developed for cancer patients undergoing potentially gonadotoxic treatments and was first described by Kutluk Oktay and collegues in 2000 in a patient who had undergone bilateral salpingo-oophorectomy by age 29 and for whom wedges of ovarian tissue had been cryopreserved. (imsociety.org)
In 2004, another pioneering group lead by Jacques Donnez achieved a livebirth after successful orthotopic transplantation of cryopreserved ovarian tissue in a woman with stage IV Hodgkin's lymphoma [2]. (imsociety.org)
The idea behind this procedure is to prevent, by reimplanting functioning ovarian tissue, debilitating conditions which occur more frequently in women after the menopause, such as cardiovascular disease and osteoporosis. (imsociety.org)
When asked her view on the issue, Xiangyan Ruan, Board member of the IMS and expert in the procedure in China, stated that "enough ovarian tissue (for example more than 20 slices) would need to be collected and cryopreserved in order to ensure hormonal preservation for that many years. (imsociety.org)
Most commonly, BTC are infused or grafted directly into a patient in the course of a blood transfusion or tissue transplant. (bristows.com)
During the healing process of this procedure, the collagen and elastic tissue beneath the skin will tighten and remodel, restoring the "V" to the Cupid's Bow and providing a more healthy, youthful shape to your lips. (marinaplasticsurgery.com)
Existing treatment strategies have limitations and associated risks the CALEC procedure aims to address through its unique approach of using a small amount of a patient's own stem cells that can then be grown and expanded to create a sheet of cells that serves as a surface for normal tissue to grow back. (worldhealth.net)
Replacing the cells of damaged tissue with other new cells from the same patient is already a reality. (sciencedaily.com)
In a breast reconstruction procedure, a tissue expander (a temporary breast implant device) is sometimes put in place and inflated with saline to prepare (shape and enlarge) the recipient site (implant pocket) to receive and accommodate the breast implant prosthesis. (wikipedia.org)
In May 2010, the Sixty-third World Health Assembly adopted resolution WHA63.22,1 in which it endorsed the updated WHO Guiding Principles on Human Cell, Tissue and Organ Transplantation and provided strategic directions to support progress in human organ, tissue and cell donation with the aim of maximizing the benefits of transplantation, meeting the needs of recipients, protecting donors and ensuring the dignity of all involved. (who.int)
Corneal disease (scarring or perforation) can be successfully addressed through transplantation in 80% of affected individuals.3 Tissue transplantation allows many recipients to return to economically productive lives and promotes their independence. (who.int)

Bortezomib is indicated for patients with multiple myeloma. (medscape.com)
It is indicated as monotherapy, in combination with dexamethasone, or in combination with lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma in patients who have received at least 1 prior line of therapy. (medscape.com)
The procedure has been used successfully to treat a variety of cancer types, including leukemia , lymphoma , multiple myeloma , myelodysplasia and solid tumors, such as testicular cancer or breast cancer . (ucsfhealth.org)
This procedure is typically used to treat blood cancers such as leukemia, lymphoma, and multiple myeloma, as well as other disorders such as sickle cell anemia and thalassemia. (vanyahealth.com)
Autologous stem cell transplantation as a platform for multiple myeloma treatment is the standard of care for patients who can safely withstand the procedure. (elsevierpure.com)

Transplants from HLA-matched siblings are associated with a lower risk of GVHD and faster recovery of the recipient's immune system following transplantation. (medscape.com)
Allogeneic transplants are significantly more dangerous and require more intensive follow-up after the transplant procedure. (ucsfhealth.org)
Without limbal cells and a healthy eye surface, patients are unable to undergo artificial cornea transplants, the current standard of vision rehabilitation. (worldhealth.net)
Haematopoietic stem cell transplants have been performed in more than 1 500 000 patients (both autologous and allogeneic) to date.1 Although haematological cancers remain the main indication, haematopoietic stem cell transplants are increasingly considered in the treatment of non-malignant disorders and genetic diseases such as haemoglobinopathies (sickle cell anaemia, thalassaemia) that can benefit greatly from this type of transplant. (who.int)

In patients with systemic sclerosis-related interstitial lung disease, a clinically meaningful decline of 10% or more in lung function was seen in 24.5% of placebo recipients, compared with 8.6% of tocilizumab recipients. (medscape.com)

Total body irradiation can lower the relapse rate but has some fatal side effects such as irreversible damage to normal internal organs and graft-versus-host disease (a complication after transplantation in which donor's immune cells recognize the host as foreign and attack the recipient's tissues). (survivornet.com)
The allogeneic HSCT was the most frequently performed (57.14%) and the most used source of Hematopoietic progenitor cells (HPC) was the peripheral blood (54.29%) and 5.71% of these patients developed the Graft versus Host Disease (GVHD), of which one was affected by acute GVHD and another by chronic GVHD. (bvsalud.org)

The choice of chemotherapy depends on several factors, including the patient's performance status, age, renal function, desire for inpatient or outpatient therapy, and likelihood of receiving future autologous stem cell transplantation. (medscape.com)
The presence of inflammatory cytokines after high-dose chemotherapy leads to proliferation and activation of MDSCs originating from autologous hematopoietic progenitors at the time of engraftment. (biomedcentral.com)
In the procedure, Burt and colleagues treated patients with chemotherapy to destroy their immune system. (scienceblog.com)
They then injected the patients with their own immune stem cells, obtained from the patients' blood before the chemotherapy, to create a new immune system. (scienceblog.com)
In an analysis reported in the Journal of Clinical Oncology , Fenske et al compared outcomes with early or late autologous vs reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation in a population of patients with chemotherapy-sensitive mantle cell lymphoma. (ascopost.com)
The study involved analysis of data from 519 patients with chemotherapy-sensitive mantle cell lymphoma receiving transplantations between 1996 and 2007 who were reported to the Center for International Blood and Marrow Transplant Research. (ascopost.com)
The early transplantation cohort was defined as patients in first partial or complete remission with no more than two lines of chemotherapy. (ascopost.com)
For example, they often use high-dose chemotherapy with special hematopoietic stem cell transplantation. (leading-medicine-guide.com)
Over a thousand new patients are given chemotherapy every year. (mediescapes.com)
[ 2 ] Options for second-line therapy in patients with relapsed/refractory disease include chemotherapy-free regimens with biologic targeted agents such as covalent Bruton tyrosine kinase (BTK) inhibitors, lenalidomide,venetoclax, and chimeric antigen receptor (CAR) T-cell therapy. (medscape.com)

Methods A retrospective case series analysis was performed with 403 patients (420 eyes) who underwent extensive fascial resection combined with autologous limbal stem cell sharing transplantation in the Department of Ophthalmology, Second People's Hospital of Yunnan Province from January 2017 to June 2018. (researchsquare.com)
The procedure is specifically indicated for fertility preservation in child and adolescent patients and patients who cannot delay cancer treatment to pursue other methods of fertility preservation such as oocyte or embryo cryopreservation[5,6]. (imsociety.org)
BACKGROUND: Cytogenomic methods have gained space in the clinical investigation of patients with disorders/differences in sexual development (DSD). (bvsalud.org)
METHODS: Twenty-two patients with DSD and syndromic features were included in the study and underwent SNP-array analysis. (bvsalud.org)
According to the authors, despite landmark studies describing an autologous stem cell approach over the past 25 years and similar methods being utilized in Europe, no U.S. research team had successfully developed a manufacturing process and quality control tests that met U.S. Food and Drug Administration (FDA) requirements or showed any clinical benefit. (worldhealth.net)
Methods: Thirty-seven adult patients booked for elective caesarean section under spinal anesthesia were randomly assigned to one of two groups. (bvsalud.org)
The aim of this study was to establish the relationship between blood transfusion and oxygen extraction ratio in adult patients admitted to the general intensive care unit, using central venous oxygen saturation instead of mixed venous oxygen saturation.Methods: Arterial and central venous blood samples were drawn and a blood gas analysis immediately before commencement of blood transfusion was undertaken. (bvsalud.org)

The clinical course and pathological results of the patient are presented with a review of the related literature. (hindawi.com)
Because of the rapidly evolving nature of this procedure, this review article provides an update on previous reviews by looking at the current evidence base regarding fat graft techniques and their effect on clinical outcome. (nih.gov)
The objective of this research was to synthesize studies that characterize the clinical and epidemiological profile of patients with leukemia, the types of treatments used, duration and outcomes for the cases. (sld.cu)
Despite these clinical improvements, the vast majority of patients eventually experience disease relapse and progression. (biomedcentral.com)
Recent clinical trials evaluating allogeneic retinal grafts derived from human embryonic stem cells (hESCs) show the procedure to be safe and potentially effective 1 . (nature.com)
His research interests include clinical trials for acute and chronic leukemia including blood and marrow transplantation and supportive care of blood and marrow transplant patients. (mayoclinic.org)
Having developed and implemented this process, it was very gratifying to see encouraging clinical outcomes in the first cohort of patients enrolled on this clinical trial. (worldhealth.net)
Below is a Question and Answer (Q&A) on how treatment, hospital appointments and clinical trials may be affected for patients. (mpeurope.org)
clinical conditions of the patient, the existence of a tumors are considered rare (KLUSMANN et al. (bvsalud.org)

The patients all had diabetes education and underwent lab tests before enrolling, since many effectively went from type 1 diabetes patients to type 2. (medpagetoday.com)
In recent years, the osteochondral autologous transplantation has been researched and proven to provide more complete surface defect coverage and increased healing times in patients that underwent this option for surgery and should be the preferred method for articular cartilage deformity repair. (wku.edu)
After informed consent was obtained, patients underwent Hidrogen-Magnetic Resonance Imaging (H-MRI) spectroscopy and were given scores according to an ALS functional rating scale, Medical Research Council power muscle scale and daily living activities. (cellsurgicalnetwork.com)
The final sample consisted of 35 records patients aged between 2 and 18 years old who underwent HSCT from February 2008 to December 2015 and who presented the data necessary for the study. (bvsalud.org)

However, it is associated with a high rate of procedure-related complications. (medscape.com)
Through established protocols 2 , fibroblasts from a skin biopsy can be returned to a pluripotent state and serve as a renewable, autologous source of replacement cells that avoids the ethical complications of hESCs. (nature.com)
To reduce the risk of these complications, special techniques are used to purify the donor's stem cells before transplantation. (vanyahealth.com)
This medical procedure carries certain risks and potential complications. (vanyahealth.com)
On the other hand, some surgeons are usually hesitant regarding CVC insertions in patients with preoperative platelet count less than 50,000/μL due to the fear of occurrence of intra- and postoperative complications. (springeropen.com)
Most complications can be managed with close attention to the patient and manipulation of the procedure, but some severe reactions and a few deaths have occurred. (msdmanuals.com)

Introduction To observe the short-term and long-term effects of extensive fascial resection combined with autologous limbal stem cell sharing transplantation for pterygium. (researchsquare.com)
Discussion and conclusion Extensive fascial resection combined with autologous limbal stem cell sharing transplantation for the treatment of pterygium, the patient's appearance satisfaction is higher, and the recurrence probability is lower than the average recurrence rate of limbal stem cell transplantation. (researchsquare.com)
Pterygium excision combined with autologous conjunctival flap transposition, pterygium excision combined with amniotic membrane transplantation, pterygium excision combined with autologous limbal stem cell transplantation and so on [12] . (researchsquare.com)
Cultivated autologous limbal epithelial cells (CALEC) procedure shown to be safe and feasible with early positive results of restored cornea surfaces or vision gains in four patients with severe chemical burns. (worldhealth.net)
A team led by researchers from Mass Eye and Ear, a member of Mass General Brigham, reports the results of a phase I trial of a revolutionary stem cell treatment called cultivated autologous limbal epithelial cell transplantation (CALEC), which was found to be safe and well-tolerated over the short term in four patients with significant chemical burns in one eye. (worldhealth.net)

Hematopoietic stem cell transplantation (HSCT) results in the alteration of several components of the immune system. (medscape.com)
Patients who undergo HSCT experience a sequential suppression of host defenses, resulting in varying infectious risk at different phases of the transplantation process. (medscape.com)
This article focuses on the common infections in patients who have undergone HSCT, the risk factors for these infections, and the approaches to their prevention and treatment. (medscape.com)
Hematopoietic stem cell transplantation (HSCT) has been shown to be effective. (medscape.com)
In the prospective Autologous Stem Cell Transplantation International Scleroderma (ASTIS) trial, a phase 3 comparison of autologous HSCT with 12 successive monthly intravenous pulses of cyclophosphamide in 156 patients with early diffuse cutaneous systemic sclerosis, HCST was associated with higher treatment-related mortality than in the first year after treatment. (medscape.com)
Non-myeloablative autologous hemopoietic stem-cell transplantation (HSCT) shows some promise in treating scleroderma. (mountsinai.org)
The Hematopoietic stem cell transplantation (HSCT) is used in children as a definitive treatment for various oncological, immune deficiencies, hemoglobinopathy, and malignancies diseases that involve the hematological system, congenital metabolism disorders, among others. (bvsalud.org)
This is a quantitative, retrospective, observational, descriptive and analytical quantitative approach approaching the medical records of children and adolescents submitted to HSCT in a referral hospital service for this type of transplantation in the state of Rio Grande do Sul North (RN). (bvsalud.org)

Risks of infection also vary with the type of transplant, the indication for transplantation, and other host factors. (medscape.com)

This allows patients to receive photo therapy treatments with less risk of severe burning or pathogenic exposure to more harmful wide band radiation ranges. (mediescapes.com)
In this article, we take a look at some of these areas and comment on the impact these revisions might have on patients and BTC-based treatments in the EEA and Northern Ireland. (bristows.com)
Patients looking for Restylane for facial filler treatments and lip injections in Cleveland, Ohio trust board-certified and fellowship-trained facial plastic surgeon, Dr. Harmych, for all non-surgical lip enhancement and dermal filler procedures. (harmychplasticsurgery.com)
The "Remington Lip" is an exciting procedure that combines specific laser treatments to rejuvenate the wrinkled or aged lip. (marinaplasticsurgery.com)
Patients are at a higher risk from COVID-19 because myeloma and AL amyloidosis, and their treatments, weaken the ability of the immune system to fight infection. (mpeurope.org)
Advice may also depend on the circumstances within a specific country, such as the number of COVID-19 patients, capacity of intensive care units, the availability of alternative treatments and national guidance. (mpeurope.org)

The patient died of this disease 22 days after his presentation. (wikipedia.org)
In patients with renal failure or highly aggressive disease, therapy with vincristine, Adriamycin (doxorubicin), and dexamethasone (VAD) may be preferred. (medscape.com)
Within 10 to 15 years after onset of the disease, most patients with this relapsing-remitting MS progress to a later stage called secondary progressive multiple sclerosis. (scienceblog.com)
The disease also stabilized in all patients. (scienceblog.com)
Patients had pancreatitis for an average of 5 years and most were idiopathic or inherited the disease. (medpagetoday.com)
CONDITIONING: Patients receive fludarabine intravenously (IV) once daily (QD) on days -7 to -5, and undergo TMLI twice daily (BID) on days -4 to 0 in the absence of disease progression or unacceptable toxicity. (survivornet.com)
GVHD PROPHYLAXIS: Patients receive cyclophosphamide IV QD on days 3-4 in the absence of disease progression or unacceptable toxicity. (survivornet.com)
Induced pluripotent stem cells (iPSCs) generated from patient fibroblasts could potentially be used as a source of autologous cells for transplantation in retinal disease. (nature.com)
Patient-derived iPSCs, however, would still harbor disease-causing mutations. (nature.com)
This important proof-of-concept finding supports the development of personalized iPSC-based transplantation therapies for retinal disease. (nature.com)
Although the original disease-causing mutation would still be present in patient iPSCs, precise mutation correction is possible through gene editing techniques adapted from the bacterial clustered regularly interspersed short palindromic repeats (CRISPR)/Cas9 system 3 . (nature.com)
The only successful treatment for end stage liver disease is liver transplantation but this has several problems in addition to the risk from the operation itself: Organ supply is limited and patients unfortunately frequently succumb on the liver transplant waiting list before a suitable organ becomes available. (ukri.org)
For patient education information, see the Cancer Center , as well as Lymphoma (Hodgkin's Disease and Non-Hodgkin's Lymphoma) and Cancer of the Mouth and Throat . (medscape.com)
Scientists are exploring an innovative cellular therapy that uses stem cells to treat Crohn's disease, a chronic genetic disease which has considerable impact on the quality of life of the patients. (sciencedaily.com)
In this line, Hospital Clínic, Barcelona is exploring an innovative cellular therapy that uses stem cells to treat Crohn's disease, a chronic genetic disease that affects 1% of the population in Spain and which has considerable impact on the quality of life of the patients. (sciencedaily.com)
With this therapy, in an average follow-up period of 6 years, 80% of transplant patients are in a phase of total remission of the disease and the remaining 20% have shown considerable improvement following the transplant, and are now responding favorably to drugs. (sciencedaily.com)
Dr. Julián Panés and Dr. Elena Ricart over the Gastroenterology Department of Hospital Clínic, Barcelona are the driving force behind this therapy in Spain and began to implement regenerative cellular therapy in patients with Crohn's disease in August 2008. (sciencedaily.com)
Patients' quality of life is conditioned by the severity of the disease and, in the most severe cases, prevents them from leading a normal life, with a very high level of suffering due to the acuteness and frequency of the intestinal symptoms. (sciencedaily.com)
As Hospital Clínic, 6 patients with Crohn's disease are already included in the process and, following the international examples, increasing numbers of patients are expected to choose this option to treat the disease in a state that was, to date, practically untreatable. (sciencedaily.com)
However, over the course of the disease, as much as 70% of severe patients require surgery to remove segments affected by the disease, due to failure of the pharmacologic approach. (sciencedaily.com)
Facial deformities caused by the disease cause social and psychological problems to affected patients. (bvsalud.org)
There is no weight gain (contraindicated in patients with inflammatory bowel disease or cirrhosis). (diabetescrunch.com)
Formerly, negative pressure isolation room, an AIIR is a single-occupancy patient-care room used to isolate persons with a suspected or confirmed airborne infectious disease. (cdc.gov)

GVHD has been reported after syngeneic and autologous transplantation but is rare. (medscape.com)

Several studies have demonstrated a reduction of new skin ulcers and accelerated healing of nondigital ulcers for certain scleroderma patients after taking Bosentan. (mountsinai.org)

We believe that this low invasive procedure can be a useful technique for AFF treatment. (hindawi.com)
All problems (adverse events) related to a medicine or medical device used for treatment or in a procedure should be reported to the Medicines and Healthcare products Regulatory Agency using the Yellow Card Scheme . (nice.org.uk)
The 21 patients in the trial, ages 20 to 53, had relapsing-remitting multiple sclerosis that had not responded to at least six months of treatment with interferon beta. (scienceblog.com)
Among 30 patients and 6 months after treatment, an average HbA1c level of 6.8% was achieved, and 71% of patients had levels that were at target, reported Sushela Chaidarun, MD, PhD , of Dartmouth-Hitchcock Medical Center in Lebanon, N.H., and colleagues. (medpagetoday.com)
and since most of the patients still had islet graft function with normal c-peptide levels after the procedure, they started treatment for patients who needed further diabetic control with drugs like metformin and dipeptidyl peptidase-4 inhibitors and not insulin. (medpagetoday.com)
They concluded that TPIAT should be seen as a viable treatment option for patients with intractable chronic pancreatitis, especially because patients experienced less pain, were able to return to work, and reported a better quality of life. (medpagetoday.com)
Stem cell transplantation is an increasingly effective form of treatment for patients with blood cancer such as leukemia, lymphoma, and myeloma. (science20.com)
As he was one of the first doctors to introduce this technique in India, he was fortunate enough to be consulted by thousands of patients who were not responding to other treatment modalities and this has given him a enormous experience in treating vitiligo. (mediescapes.com)
This complex treatment offers a huge benefit for patients: even more resistant cancer cells are killed by the more intensive treatment process. (leading-medicine-guide.com)
For patients older than 55 years, a TKR is the treatment of choice. (drlintner.com)
As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein. (drcalapai.com)
Hematopoietic blood stem cell transplantation-a cell therapy-was first explored in humans in the 1950s and is currently a well-established treatment for blood diseases. (pharmaceuticalcommerce.com)
Since CGTs are generally a treatment of last resort, patients are often very sick. (pharmaceuticalcommerce.com)
In this grant we are seeking to turn these encouraging results into a treatment for patients with cirrhosis. (ukri.org)
Patients having Restylane lip injection treatment should plan for about 24 hours of downtime. (harmychplasticsurgery.com)
Since the late 1960s, treatment outcomes for pediatric patients with non-Hodgkin lymphoma have steadily improved. (medscape.com)
According to the study published August 18 in Science Advances, the patients who were followed for 12 months experienced restored cornea surfaces -- two were able to undergo a corneal transplant and two reported significant improvements in vision without additional treatment. (worldhealth.net)
Cornea specialists have been hindered by a lack of treatment options with a high safety profile to help our patients with chemical burns and injuries that render them unable to get an artificial cornea transplant. (worldhealth.net)
To date, a total of 6 patients are benefiting from this new treatment, of whom 3 I've already completed the process and are in the follow-up face, and a further 3 are at different stages of therapy. (sciencedaily.com)
in Italy, the treatment has been applied to 4 patients, 3 of whom are also showing excellent progress following the transplant. (sciencedaily.com)
it is very important that patients speak to their doctor, nurse or healthcare team to discuss specific questions relevant to their treatment and care. (mpeurope.org)
Patients should continue attending hospital appointments and taking their treatment as normal, unless instructed otherwise by their doctor, nurse or healthcare team. (mpeurope.org)
Will the treatment of myeloma and AL amyloidosis patients be affected during the COVID-19 outbreak? (mpeurope.org)
Myeloma and AL amyloidosis patients should be prepared for changes to their treatment during the COVID-19 outbreak. (mpeurope.org)
Doctors will balance the risks and benefits of patients attending hospital appointments to receive their treatment. (mpeurope.org)
In collaboration with patients, they will assess whether any treatment changes can be made to reduce the number of hospital visits. (mpeurope.org)
Patients should speak to their doctor, nurse or healthcare team about whether their treatment will be affected during this time. (mpeurope.org)
Advice that patients receive about treatment changes will vary and depend on individual circumstances. (mpeurope.org)
For some patients their treatment will continue as normal. (mpeurope.org)
Stopping treatment altogether, where clinically appropriate to do so (e.g. where a patient is in good remission). (mpeurope.org)
Any treatment changes should be made in discussion between a patient, their doctor and healthcare team. (mpeurope.org)
Patients should speak directly to their doctor, nurse or healthcare team if they have any questions or concerns about treatment changes during this time. (mpeurope.org)
Gastrointestinal toxicities were the most frequent (97.1%) and all patients received antineoplastic/chemotherapeutic and antiemetic treatment. (bvsalud.org)
In this debate, we discuss which of these approaches will evolve to be the treatment of choice for Parkinsonian patients in the future. (lu.se)
The transplantation of human tissues, organs or cells is an established form of treatment that has been acknowledged as the best and very often only life-saving therapy for several serious and life-threatening congenital, inherited and acquired diseases and injuries. (who.int)
Organ transplantation is often the best, if not the only, treatment for acute and chronic organ failure. (who.int)
The research could open the way for this new method of treatment to be made available to older patients with cataracts. (medscape.com)
Cataracts are a very common eye condition leading to 30,000 treatment procedures in the UK each year. (medscape.com)

TRANSPLANT: Patients undergo hematopoietic cell transplantation on day 0. (survivornet.com)
Patients may have pain, effusion, or mechanical symptoms and because of the inadequate healing response, joint mechanics can be altered and the adjacent cartilage can undergo degeneration. (drlintner.com)
The patient will undergo two surgical procedures. (drlintner.com)

Most triazole agents are not effective in vivo ( 10 ), except for posaconazole, which shows some efficacy both experimentally and in patients as second-line therapy ( 11 - 13 ). (cdc.gov)
In elderly patients or patients in whom autologous transplantation is not possible in the future, melphalan and prednisone (MP) therapy is preferred because of its ease of administration and low toxicity. (medscape.com)
Noble Clinic is now equipped with Narrow Band UV Therapy Daavlin USA and Excimer laser, the latest laser machine to medically treat vitiligo patients. (mediescapes.com)
The patient received liver support therapy, and the serum hepatic enzymes recovered to normal levels. (journaltocs.ac.uk)
Stem cell-derived cell transplantation in the eye is one therapy being explored for inherited retinal degenerations such as retinitis pigmentosa (RP). (nature.com)
Starting materials most often originate from the patient, and the final therapy is infused back into the same patient. (pharmaceuticalcommerce.com)
Gene therapy was first introduced in the late 1970s, and the first trial in humans began in 1990 when colleagues at the National Institutes of Health (NIH) performed the first-approved gene therapy procedure on a 4-year-old with severe combined immunodeficiency (SCID). (pharmaceuticalcommerce.com)
Starting materials most often originate from the patient, are sent to a manufacturing site to create the therapy, delivered back to the same patient's bedside, and infused into the patient. (pharmaceuticalcommerce.com)
One delay or a temperature excursion that renders a therapy obsolete can mean life or death for a patient. (pharmaceuticalcommerce.com)
He has been awarded RO1 funding in the past for the use of autologous dendritic cell therapy for chronic myeloid leukemia. (mayoclinic.org)
Hospital Clínic de Barcelona is one of the few hospitals in the world to instate cellular therapy using autologous stem-cell transplantation. (sciencedaily.com)
Sections on the prevention of bacterial pneumonia in mechanically ventilated and/or critically ill patients, care of respiratory-therapy devices, prevention of cross-contamination, and prevention of viral lower respiratory tract infections (e.g., respiratory syncytial virus {RSV} and influenza infections) have been expanded and updated. (cdc.gov)
Traditional preventive measures for nosocomial pneumonia include decreasing aspiration by the patient, preventing cross-contamination or colonization via hands of personnel, appropriate disinfection or sterilization of respiratory-therapy devices, use of available vaccines to protect against particular infections, and education of hospital staff and patients. (cdc.gov)

CONCLUSIONS: Stem-cell transplantation in the motor cortex delays ALS progression and improves quality of life. (cellsurgicalnetwork.com)

Other problems with transplantation are that immunosuppression increases the risk of renal failure, cancer and severe infections. (ukri.org)

The mainstay of their procedures most often involved resection of the suspensory ligament of the penis, with pubic lipectomy ans release of a penoscrotal web as needed. (chirurgie-intime.com)

The procedure is called autologous non-myeloablative haematopoietic stem-cell transplantion. (scienceblog.com)

The early transplantation cohort consisted of 249 patients receiving autologous stem cell transplantation and 50 receiving reduced-intensity conditioning allogeneic stem cell transplantation. (ascopost.com)
The late transplantation cohort consisted of 132 patients receiving autologous stem cell transplantation and 88 receiving allogeneic stem cell transplantation. (ascopost.com)
Facilities for both autologous and Allogenic transplantation are available at the hospital, using a cell separator for stem cell harvest procedures and a freezing system to cryo-preserve the cells for future use. (mediescapes.com)
Deferring procedures such as autologous stem cell transplantation to a future date, where clinically appropriate to do so. (mpeurope.org)
How will autologous stem cell transplantation be affected during the COVID-19 outbreak? (mpeurope.org)
Stem-cell transplantation into the frontal motor cortex in amyotrophic lateral sclerosis patients. (cellsurgicalnetwork.com)
Lack of response to initial induction did not preclude a good response after stem cell transplantation. (elsevierpure.com)
Commenting on the study in a statement, Dr Dusko Ilic, reader in stem cell science at King's College London, says: "The basic science research led to the hypothesis that preserving and stimulating autologous stem cells in the eye might promote regeneration of a surgically removed lens. (medscape.com)

This brings as oral dopamine therapies with the advantage that with it continued infective risks for the patients the cells can be targeted to the site where dopamine with DBS which is not so for patients with trans- is most needed, namely the striatum. (lu.se)
The present report aims to provide a comprehensive analysis of the current situation and facilitate a forward-looking discussion on actions for improving access to transplantation therapies. (who.int)

The late transplantation cohort was defined as all remaining patients. (ascopost.com)
During outbreaks, healthcare personnel may be assigned to a cohort of patients to further limit opportunities for transmission (cohorting staff). (cdc.gov)

As with any procedure, there could be pain or other substantial risks involved. (drcalapai.com)

This is a surgical procedure worth promoting. (researchsquare.com)
To add on the uniqueness of this case, the hyaline cartilage repair was performed in a fashion that has been recently proven to be more effective than traditional microfracture surgery while still being able to be performed in the same surgical procedure. (wku.edu)
The aim of this study is to report a case of progressive hemifacial atrophy treated with dermis-fat graft and demonstrate that this surgical procedure may improve the aesthetic appearance of the patient's face and discuss the therapeutic aspects of this disorder. (bvsalud.org)
A written informative consent was signed by all parents or guardians for the surgical procedure, anesthesia, and data use. (springeropen.com)

He has undergone training in Autologous melanocyte transplantation in Sweden in 1997. (mediescapes.com)
Since 1997 more than 4500 patients have undergone melanocycle transplantation in our clinic. (mediescapes.com)

Outcomes of corneal transplantation in Europe: report by the European Cornea and Cell Transplantation Registry. (who.int)

The authors also reported at the Endocrine Society annual meeting that patients improved their diabetes-related outcomes after initially undergoing off-site islet isolation, during which the pancreas is taken out of the body (procedure done at Massachusetts General Hospital in Boston) before transitioning to on-site autologous islet transplantation. (medpagetoday.com)
She added that the mass of the islets in the on-site procedure correlated with favorable outcomes. (medpagetoday.com)

Currently, most transplant procedures involve collecting stem cells from the peripheral blood. (ucsfhealth.org)

RESULTS: The autologous transplantation of CD133(+) stem cells into the frontal motor cortex is a safe and well-tolerated procedure in ALS patients. (cellsurgicalnetwork.com)

Since severe loading pain continued for approximately 3 months, surgical procedures were considered to be necessary for fear of a complete fracture. (hindawi.com)
BOSTON -- Patients with severe medically refractory chronic pancreatitis experienced preserved islet function after total pancreatectomy with islet auto-transplant (TPIAT), leading to a lower rate of insulin-dependent diabetes, researchers reported here. (medpagetoday.com)

In the rhinocerebral or pulmonary forms, patient death rates are reported to be as high as 60% because of delayed diagnosis or delayed therapeutic management ( 7 - 9 ). (cdc.gov)
Central venous catheters (CVCs) have a crucial role in pediatric patients who are undergoing such therapeutic procedure. (springeropen.com)

To generate healthy patient-derived cells, mutations might be repaired with new gene-editing technology based on the bacterial system of clustered regularly interspersed short palindromic repeats (CRISPR)/Cas9, thereby yielding grafts that require no patient immunosuppression. (nature.com)

Over the past 20 years, there has been a dramatic increase in the use of autologous fat grafting to treat volume and contour defects in aesthetic and reconstructive surgery. (nih.gov)
Surgery for chronic pancreatitis has become more and more common, often depriving patients from beta cells with the need to treat them with insulin replacement as we do in individuals with type 1 diabetes," Joel Zonszein, MD , at the Albert Einstein College of Medicine in New York City, told MedPage Today . (medpagetoday.com)
Dr. Harmych's exclusive focus is plastic surgery of the face and neck and he performs many Restylane procedures. (harmychplasticsurgery.com)
See before & after photos of actual patients from Marina Plastic Surgery. (marinaplasticsurgery.com)
The surgical method is another option that Dr. Stevens and Marina Plastic Surgery have helped many Los Angeles lip augmentation patients with. (marinaplasticsurgery.com)
Many of our Los Angeles Lip Augmentation patients combine their lip augmentation procedure with other facial sculpting procedures, such as a brow lift , eyelid surgery , and rhinoplasty . (marinaplasticsurgery.com)
The surgery is occasionally very aggressive for the patient, as it is sometimes necessary to remove the entire colon or large sections of the small intestine, thereby considerably affecting the absorption of food by the intestine, with a resulting deterioration in quality of life and body image (colostomy bag). (sciencedaily.com)
Provision of information relating to surgery and anesthesia to patients has been proven to have benefit in allaying anxiety. (bvsalud.org)

Autologous hematopoietic cell transplantation for adult acute myeloid leukemia: An obsolete or resurfacing concept? (umn.edu)
Dive into the research topics of 'Autologous hematopoietic cell transplantation for adult acute myeloid leukemia: An obsolete or resurfacing concept? (umn.edu)
Three distincts classes of patients request evaluation : potent adult males, impotent males, and young lads brought in by worrisome parents. (chirurgie-intime.com)
Objective: To determine the effect of video information in addition to the pre-anesthetic review on the mean preoperative State anxiety inventory (STAI-S) score in adult patients presenting for elective caesarean section under spinal anesthesia at Aga Khan University Hospital, Nairobi (AKUHN), and to determine the prevalence of preoperative anxiety in the obstetric population presenting for elective caesarean section at AKUHN. (bvsalud.org)
Discussion: The change in oxygen extraction ratio was not statistically significant following blood transfusion in adult patients admitted to the general ICU at a tertiary teaching hospital. (bvsalud.org)

For this reason, the advice is for myeloma and AL amyloidosis patients to stay at home to reduce the likelihood of catching COVID-19. (mpeurope.org)

This can be done at smaller institutions, too, and it's a good option for some patients with intractable chronic pancreatitis. (medpagetoday.com)
For chronic or acute liver failure, as well as some cardiorespiratory conditions, the only alternative to transplantation is death. (who.int)

Researchers from Northwestern University's Feinberg School of Medicine appear to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby "resetting" their immune systems. (scienceblog.com)
After the transplantation, the patient's new lymphocytes or immune cells are self-tolerant and do not attack the immune system. (scienceblog.com)
In previous studies, Burt had transplanted immune stem cells into late-stage MS patients. (scienceblog.com)

The before and after photographs presented in the Restylane and lip injection before and after gallery depict actual patients of Cleveland, Ohio facial plastic surgeon Dr. Brian Harmych and have been used with written permission. (harmychplasticsurgery.com)

It is concluded a prevalence of leukemia in pediatric patients, with a predominance of the subtype Acute Lymphoblastic Leukemia (ALL). (sld.cu)

The OATs procedure involves using small plugs of articular cartilage transplanted into the area in hopes of a faster recovery. (wku.edu)

The patient was then referred to the hospital for diagnostic imaging, where is was concluded that the athlete suffered from ACL, Meniscus, and articular cartilage tears. (wku.edu)
The transplant requires several weeks of admission to hospital before patients receive their own cells. (sciencedaily.com)
All the included patients had CVC insertions 12 days before the commencement of BMT as per the adopted protocol within our hospital. (springeropen.com)

Anatomy19

Organisms7

Diseases42

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment98

Phenomena and Processes20

Disciplines and Occupations1

Information Science3

Named Groups2

Health Care26

Allogeneic transplantation10

ASCT10

Chondrocyte transplantation1

Donor8

Bone25

Survival12

Patient's own blood1

Tissue12

Multiple myeloma5

Transplants4

Recipients1

Graft Versus2

Chemotherapy10

Methods7

Clinical9

Underwent4

Complications6

Limbal5

HSCT8

Type of transplant1

Treatments6

Disease23

Syngeneic1

Scleroderma1

Treatment38

Undergo3

Therapy13

Progression1

Renal failure1

Resection1

Haematopoietic1

Stem cell8

Therapies2

Cohort2

Risks1

Surgical procedure4

Undergone2

Corneal1

Outcomes2

Peripheral blood1

Safe and well-tolerated1

Severe2

Therapeutic2

Immunosuppression1

Surgery8

Adult5

Myeloma1

Chronic2

Immune3

Facial1

Pediatric1

Involves1

Hospital3