Patients histology mucinous adenocarcinoma. Medical search. Frequent questions

With recent advancements in pathology, gene expression profiling, identification of subtypes and various modalities available for exploring the GI tract, it has become possible to find the precise origin of mucinous tumors. (thieme-connect.de)
By contrast, a rare subset of CRC tumors that show microsatellite instability (MSI-high) demonstrate marked responses to PD-1 therapy, similar to or exceeding that observed in other highly mutated cancers such as melanoma and lung adenocarcinoma. (cancer.gov)
New insights emerged last decade that enriched our knowledge regarding the biological behavior of appendiceal neuroendocrine tumors (NETs), which range from totally benign tumors less than 1cm to goblet cell carcinomas which behave similarly to colorectal adenocarcinoma. (wjgnet.com)
By the time of diagnosis, 90% of patients have locally advanced tumors that have involved retroperitoneal structures, spread to regional lymph nodes, or metastasized to the liver or lung. (msdmanuals.com)
An increasing number of patients are presenting with peritoneal carcinomatosis, or widespread metastasis of the peritoneum, which can result from a variety of tumors, including digestive and gynecologic malignancies. (oncnursingnews.com)
Patients with tumors that are aggressive or have metastasized are not good candidates for this treatment, regardless of where their tumor originated," said El-Rayes. (oncnursingnews.com)
Successful diagnosis and treatment of patients with salivary gland tumors require a thorough understanding of tumor etiology, biologic behavior of each tumor type, and salivary gland anatomy. (medscape.com)
Diagnosis of hereditary tumors may also change the cancer treatment strategy for the diagnosed patient. (ejgo.net)
Patients with MOC seem to be 2.3 times more likely to die of their tumors when compared to women with serous EOC. (biomedcentral.com)
women with mixed histologies including mucinous tumors combined with endometrioid, serous, clear-cell, and/or other histologic types were excluded. (biomedcentral.com)
The accelerated FDA approval of entrectinib for the treatment of adult patients with solid tumors that harbor NTRK gene fusions was based on the results from an integrated analysis of three phase I/II trials conducted at more than 150 sites in 15 countries: ALKA-372-001, STARTRK-1, and STARTRK-2 [6]. (memoinoncology.com)
Tumors of the pancreas that contain substantial cystic components include mainly mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, solid pseudopapillary tumor, and cystadenomas (which encompass microcystic, macrocystic/oligocystic, and rare solid serous adenomas). (hindawi.com)
Pancreatic cystic tumors fall into the serous or mucinous category. (hindawi.com)
These tumors are managed expectantly and surgical management is considered only when the patient becomes symptomatic [ 2 ]. (hindawi.com)
The remaining 44% were composed of carcinomas not otherwise specified and a variety of uncommon tumors: large cell, clear cell, solid, bronchoalveolar, adenosquamous, epithelial hemangioendothelioma, oat cell, carcinoid, small cell and mucinous histological types. (biomedcentral.com)

Stage 2 assessed whether the specific criteria defined in Stage 1 could identify pancreatic cystic neoplasms (PCN) including intraductal papillary mucinous neoplasms, mucinous cystic adenoma, or adenocarcinoma in an off-line blinded consensus review. (elsevierpure.com)
Studies evaluating rate and histology of appendiceal neoplasms between complicated and uncomplicated appendicitis include small number of patients. (sglaresearchfoundation.org)
Contrasting information was derived through a literature review by Louredo et al, which indicated that in pediatric patients, most salivary gland neoplasms (75.4%) are malignant. (medscape.com)
Salivary gland neoplasms occurred with slightly greater frequency in girls (57.4% of patients) than in boys. (medscape.com)
However, how Sp17 expression varies with histology, grade, and stage of EOC and its expression in other ovarian neoplasms has not been defined. (biomedcentral.com)
The study included 982 patients with benign, borderline, and malignant ovarian neoplasms and normal ovary. (biomedcentral.com)
Thirteen individuals with FPC (6.1%) underwent surgical resection for a suspected PRL, but only four (1.9%) had high-risk lesions (ie, high-grade intraductal papillary mucinous neoplasms or grade 3 pancreatic intraepithelial neoplasms). (medscape.com)
2 Moreover, up to 10% of patients with intraductal papillary mucinous neoplasms (IPMNs), which are pre-malignant lesions, may be initially incorrectly diagnosed with CP. (practicalgastro.com)
INTRODUCTION Since the 1st description more than three decades ago1, intraductal papillary mucinous neoplasm (IPMN) of the pancreas has become widely recognized as one of the most common cyst-forming pancreatic neoplasms, and several variants of intraductal neoplasms have been described including the gastric, intestinal, or pancreatobiliary subtypes2C9. (opioid-receptors.com)

Nevertheless, a case of mucinous adenocarcinoma with metaplasia has been discovered in a TAG1 with a 23-year old patient. (scirp.org)
Fifty-four cases (41.9%) had histologically normal appendices, while 75 cases (58.1%) had various histopathologically demonstrable lesions ranging from acute appendicitis (the most frequent with 27%) to neoplasia (one case of mucinous adenocarcinoma). (bvsalud.org)

It has a better prognosis than traditional ductal adenocarcinoma. (msdmanuals.com)
Purpose Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis. (medscape.com)
Primary pancreatic ductal adenocarcinoma can obstruct the main PD (MPD) and cause symptoms of AP or exocrine pancreatic insufficiency (EPI). (practicalgastro.com)
Pancreatic ductal adenocarcinomas (PDACs) overexpress pro-angiogenic factors but are not viewed as vascular. (oncotarget.com)
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the United States, with dismal overall 5-year survival rates of 6% [ 1 ]. (oncotarget.com)
We report a case of ductal carcinoma diagnosed within a squamous epithelial inclusion cyst within an axillary lymph node in a patient with pure ductal carcinoma in situ (DCIS) of the ipsilateral right breast. (hindawi.com)
Despite the troubles of 41575-94-4 determining the degree of invasive carcinoma in many cases, the overall end result appears relatively beneficial and considerably better than that of standard ductal adenocarcinoma, even when only the instances with invasive carcinoma are considered. (opioid-receptors.com)

The purpose of this case-control study was to compare the prognoses of women with stage III mucinous ovarian carcinoma (MOC) who received maximal or optimal cytoreduction followed by paclitaxel plus carboplatin chemotherapy to those of women with stage III serous epithelial ovarian cancer (EOC) treated in the similar manner. (biomedcentral.com)
We wondered whether the worse prognosis associated with mucinous histology is also valid when age, tumor grade, substage of disease, and extent of RD are matched with serous histology in women with stage III EOC who have undergone primary CRS followed by standard intravenous paclitaxel plus carboplatin chemotherapy. (biomedcentral.com)
Serum concentrations were higher in patients with Sp17 tissue expression, and the highest concentrations were noted among patients with serous and clear cell adenocarcinomas. (biomedcentral.com)

However, several studies demonstrated that high CD73 expression was not correlated with the prognosis of patients with breast cancer [ 10 ]. (biomedcentral.com)
To date, there is no study to comprehensively investigate the correlation between high CD73 expression and prognosis in cancer patients. (biomedcentral.com)
In these cases, it is critical to determine whether the secondary tumor is an independent primary tumor or a recurrence or metastasis of the first primary tumor, because this determination influences how the disease is staged and managed as well as the patient prognosis. (biomedcentral.com)
Most patients with MOC are diagnosed at an early stage and therefore it confers a favorable prognosis [ 3 ]. (biomedcentral.com)
Early T stage GBC patients with distant metastasis are proven to have a worse prognosis. (medsci.org)
Conclusions In patients with completely staged ovarian clear cell carcinoma, those with stage IA/IC1 disease have an excellent prognosis, regardless of chemotherapy. (bmj.com)
Correctly interpret the diagnoses of the pathologic conditions mentioned above, with a clear understanding of their value for the definition of patient prognosis and treatment. (unibo.it)

While there was no significant difference in overall rate of neoplasm between complicated and uncomplicated appendicitis, NET rate was significantly higher in uncomplicated appendicitis while Adenocarcinoma rate was significantly higher in complicated appendicitis. (sglaresearchfoundation.org)

Patients with malignant lesions typically present after age 60 years, whereas those with benign lesions usually present when older than 40 years. (medscape.com)
For patients with resected T2 lesions, 16% have been found to have distant metastasis [ 3 ]. (medsci.org)
US combined with US guided FNAC is now recommended as the investigation method of first choice for HN lesions for evaluating regional metastases in HN patients, for both those with and those without palpable lumps. (ellibs.com)
Whether patients with orofacial granulomatoses will subsequently develop intestinal manifestations of Crohn disease is uncertain, but histologic similarities between the oral lesions and the intestinal lesions are obvious. (medscape.com)

We identified a unique case of triple SLC, including adenocarcinoma, squamous cell carcinoma, and mixed small and large cell neuroendocrine carcinoma, which has poor prognostic implications. (biomedcentral.com)

Genetic testing is now offered routinely to all patients diagnosed with pancreatic cancer. (msdmanuals.com)
Pancreatic cancer causes diabetes in up to half of patients, leading to symptoms of glucose intolerance (eg, polyuria and polydipsia). (msdmanuals.com)
Patients and Methods Screening outcomes were collected from three European centers that conduct prospective screening in high-risk groups including families with clustering of PDAC (familial pancreatic cancer [FPC]) or families with a gene defect that predisposes to PDAC. (medscape.com)
Approximately 2% of patients with "newly-diagnosed" CP may have underlying pancreatic malignancy. (practicalgastro.com)
Moreover, patient-derived orthotopic xenografts can exhibit tumor angiogenesis, whereas conditioned media (CM) from KRC-derived pancreatic cancer cells (PCCs) enhance endothelial cell (EC) growth and migration, and activate canonical TGF-β signaling and STAT3. (oncotarget.com)

He had recently been diagnosed with adenocarcinoma in the right upper lobe, with a poorly differentiated carcinoma favoring squamous cell cancer based on bronchoalveolar lavage of the right lower lobe for which treatment was started. (biomedcentral.com)

Elevated expression levels of miR-205 have been shown to be associated with mucinous colorectal cancers and mucin-producing ulcerative colitis-associated colon cancers, but not with sporadic colonic adenocarcinoma that lack mucinous components. (wikipedia.org)
The organization strives to foster research collaboration between medical and surgical oncologists at cancer centers that provide HIPEC, and it published its first recommendations in 2014, focusing on the delivery of HIPEC to patients with peritoneal carcinomatosis from colorectal cancer. (oncnursingnews.com)
Molecular pathology of colorectal cancer syndromes from Saudi patients. (org.sa)
Genetic risks for colorectal cancer in Saudi patients. (org.sa)
Somatic mutations in colorectal cancer from Saudi patients. (org.sa)

Results: A total of 66 patients underwent nCLE imaging and images were available for 65, 8 of which were subsequently excluded due to insufficient information for consensus reference diagnosis. (elsevierpure.com)
The incidence of these tumours has increased by 54% during the past decade, reaching 0.97 cases per 100,000 population in the USA, probably indirectly related to the higher use of computed tomography (CT) scan that allows early diagnosis in asymptomatic patients [ 1 ]. (karger.com)
This new classification strategy is based on a multidisciplinary approach to diagnosis of lung adenocarcinoma that incorporates clinical, molecular, radiologic, and surgical issues, but it is primarily based on histology. (qxmd.com)
The diagnosis of peritoneal carcinomatosisis can be devastating, but a combination of cytoreductive surgical resection and hyperthermic intraperitoneal chemotherapy has the potential to provide some patients with long-term survival. (oncnursingnews.com)
1 The diagnosis is devastating, with treatment often limited to palliation of symptoms, but a combination of cytoreductive surgical resection (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)-sometimes referred to as "hot chemotherapy bath"—has the potential to provide some patients with long-term survival. (oncnursingnews.com)
Currently, surgical resection is the only potentially curative treatment for PDAC, but in approximately 80% of symptomatic patients, the tumor is already unresectable at the time of diagnosis. (medscape.com)
Tumour classification systems provide the foundation for tumour diagnosis and patient therapy and a critical basis for epidemiological and clinical studies. (ersjournals.com)
The average age of the SLE patients at lung cancer diagnosis was 60 years (median 40, standard deviation (SD) 10.9). (biomedcentral.com)
Available gross photographs and descriptions as well as all histologic sections were re-evaluated to confirm the diagnosis and further characterize the spectrum of histology findings. (opioid-receptors.com)
Haemoperitoneum seen at laparotomy suggested a diagnosis of ectopic pregnancy .The diagnosis of ruptured corpus luteum cyst (RCLC) was made only after histology. (bvsalud.org)

2 ], who observed an increase in the incidence in the last decades, especially in women, and again mucinous adenocarcinoma being the one with the highest prevalence (48%), pointing to an increased incidence of mucinous adenocarcinoma in men (1.0 per million person-years) and women (1.9 per million person-years). (karger.com)
The incidence of synchronous lung cancer (SLC) ranges from 0.2 to 8% [ 3 ], whereas continuous exposure to smoking increases the risk that a patient will develop metachronous primary lung cancer. (biomedcentral.com)
Recent research has also revealed clinical, radiologic, and pathologic correlates, leading to greater knowledge in molecular profiling and targeted therapeutics, as well as an emphasis on the rising incidence of adenocarcinoma histology. (scienceopen.com)
The peak incidence is in the third decade of life for non-seminomatous germ cell tumour (NSGCT) and mixed GCT patients, and in the fourth decade for seminoma testis (ST) patients. (uroweb.org)

MOC is mostly diagnosed in patients at a younger age than patients with other types of epithelial ovarian cancers and the only clinical risk factor associated is tobacco smoking. (thieme-connect.de)
Like other pediatric cancers, those of the GI tract differ from corresponding cancers in adults in terms of histology, pathogenesis, and clinical presentation. (medscape.com)
Our patient had triple synchronous primary lung cancers that histologically were variant primary cancers. (biomedcentral.com)
Patients with lung cancer are at an increased risk of developing secondary lung cancers at the same time as the first (synchronous) or later in life (metachronous). (biomedcentral.com)
The fact that our patient had three different primary cancers made treatment challenging. (biomedcentral.com)
As advances in medicine have continued, more and more patients have undergone this type of therapy for treatment of a wide array of cancers," he said in an interview with Oncology Nursing News . (oncnursingnews.com)
Therapeutic Implications of Germline Testing in Patients with Advanced Cancers. (ejgo.net)
Mohs surgery is a surgical technique used to treat various skin cancers that allows precise microscopic control of the margins by utilizing tangentially cut frozen-section histology. (medscape.com)

Adoption of the GYNECARE INTERCEED absorbable adhesion barrier for appropriate gynecologic surgeries would likely result in significant savings for hospitals, driven primarily by clinical patient benefits in terms of decreased length of stay and adhesion-related readmissions. (endometriosi.it)
All patients provided an informed consent at admission for storage of their clinical information and for research use of their clinical data. (biomedcentral.com)
Patients were enrolled into specific treatment cohorts using only blood-based NGS testing, to establish its clinical utility as a stand-alone test. (memoinoncology.com)
Overall, these results demonstrated the clinical utility of blood-based NGS as a method to inform clinical decision making in patients with ALK -positive NSCLC. (memoinoncology.com)

This is an open label Phase 1b/2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or in combination with ultralow dose gemcitabine in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignature® test status. (uclahealth.org)

METHODS: The study included 265 patients who underwent initial surgery at the National Cancer Center Hospital between 1997 and 2019 and were pathologically diagnosed with endometrial cancer. (bvsalud.org)
The databases consisted of individual patients with EOC who underwent upfront surgery between January 1998 and December 2016 at seven gynecologic oncology departments in Turkey. (biomedcentral.com)
Patients and Methods: The study included 157 patients with diagnosed pT1N+ or pT2-3N0 gastric cancer who underwent radical gastrectomy at our institution between January 2001 and December 2020. (cancerdiagnosisprognosis.org)
This retrospective study collected data from 914 patients who underwent gastrectomy for gastric cancer between January 2001 and December 2020 at the Nagasaki University Graduate School of Biomedical Science. (cancerdiagnosisprognosis.org)
Patients who underwent neoadjuvant chemotherapy (n=5) or adjuvant chemotherapy (n=3), patients with remnant gastric cancer (n=11), and a patient who underwent palliative resection (n=1) were excluded. (cancerdiagnosisprognosis.org)
Eleven years ago, the patient underwent an open laparotomy for complicated symptomatic gall stone disease and was incidentally detected to have a space occupying lesion of the head of pancreas. (hindawi.com)
Nine patients underwent fertility-sparing surgery and none experienced recurrence. (bmj.com)

To address advances in oncology, molecular biology, pathology, radiology, and surgery of lung adenocarcinoma, an international multidisciplinary classification was sponsored by the International Association for the Study of Lung Cancer, American Thoracic Society, and European Respiratory Society. (qxmd.com)
Full knowledge of normal anatomy, histology and embriology are necessary to understand Anatomic Pathology. (unibo.it)
7 , 8 The aim of this review is to explore the molecular pathology research that has been carried out on CRC from Saudi patients, with a view to understanding the prevalence and clinicopathological correlates of clinically and biologically relevant genetic mutations in Saudi CRC patients. (org.sa)

Diagnostic assay can provide highly accurate subclassification of NSCLC patients. (wikipedia.org)
The most common EGFR mutations (nearly 85%-90%) in NSCLC patients are L858R and exon 19 deletions (Ex19del), which are defined as classical mutations. (frontiersin.org)
EGFR G724S mutation in exon 18 is a rare driver mutation, only found in about 0.3%-0.8% of NSCLC patients. (frontiersin.org)
BFAST is the first prospective trial to use blood-based NGS testing as the sole method of identifying actionable genetic alterations and assigning NSCLC patients to targeted agents or immunotherapy. (memoinoncology.com)
The global, randomized, phase III ALEX study was conducted to compare the efficacy and safety of alectinib versus crizotinib in 303 patients with treatment-naïve, ALK -positive advanced NSCLC. (memoinoncology.com)
The authors concluded that this analysis confirms the superior efficacy of alectinib in untreated ALK -positive NSCLC patients. (memoinoncology.com)

Patients and methods: Retrospective, descriptive and analytical studies were conducted by the Clinic of Houeyiho in Cotonou from January 2013 to December 2015. (scirp.org)
Patients and methods: Eight referral centers performed nCLE in patients with PCL. (elsevierpure.com)
In this talk, I will describe some endoscopic microscopy techniques developed, including optical coherence tomography (OCT), optical coherence microscopy (OCM), and confocal microscopy (CM) and will discuss how these methods can potentially impact patient care. (stanford.edu)
Methods We retrospectively identified patients with ovarian clear cell carcinoma initially treated at our institution from January 1, 1996 to March 31, 2020. (bmj.com)
Methods The study population included 620 patients with NAFLD and 405 patients with CLD-HCV, all of whom were diagnosed by liver biopsy. (go.jp)

Squamous carcinoma was by far the most common histological type (82.2%), distantly followed by adenocarcinoma (12.8%) and mesenchymal/mixed Mullerian malignancies comprising 0.01% (5 cases). (smjonline.org)

Associated tumor-related factors include rectal location, higher American Joint Committee on Cancer stage, signet/mucinous histology, and poor/undifferentiated grade. (elsevierpure.com)

The majority of patients 75 (79.8%) had early-stage (stage I/II), while 19 (20.2%) presented with advanced-stage (III & IV). (thieme-connect.de)
Among patients with early-stage (I&II), 3- and 5-year progression-free survival (PFS) was 95%, while for advanced stage (III&IV), PFS was 16% and 8%, respectively. (thieme-connect.de)
Most patients treated at our center presented with early stages and had excellent outcomes, while advanced-stage disease had dismal results. (thieme-connect.de)

In Grade 2 Atypical Transformation, the histology reveals 44.4% of CIN 1, 40.7% of severe dysplasia and 11.1% of carcinomas. (scirp.org)

Both patients had a thickened rectal wall with prominent lymphadenopathy on computed tomography (CT) scan, suspecting for malignancy. (hindawi.com)

Has-miR-205 is a highly accurate marker for lung cancer of squamous histology. (wikipedia.org)
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. (qxmd.com)
Adenocarcinoma is the most common histologic type of lung cancer. (qxmd.com)
Patients with previously treated lung cancer are at risk for developing metachronous lung cancer, but with the success of computed tomography and positron emission tomography, the ability to detect both synchronous and metachronous lung cancer has increased. (biomedcentral.com)
Later, bronchoscopy incidentally revealed the patient to have an endobronchial lesion that turned out to be mixed small and large cell neuroendocrine lung cancer. (biomedcentral.com)
After undergoing complete resection of non-small cell lung cancer, patients have a 1-2% risk per patient per year that of developing another lung cancer [ 5 ]. (biomedcentral.com)
The aim of this study was to review the evidence on lung cancer epidemiology, including data of international scope with comparisons of economically, socially, and biologically different patient groups. (scienceopen.com)
However, we found a rare mutation of EGFR Ex19del/G724S in two patients with lung cancer who demonstrated a favorable response to the combination of afatinib and chemotherapy. (frontiersin.org)
In this study, we reported two patients with EGFR Ex19del/G724S lung cancer who appeared in remission after being treated with afatinib and chemotherapy. (frontiersin.org)
Plasma or cerebrospinal fluid samples of these patients were then sequenced after treatment using a 139-lung-cancer-gene capture-based targeted panel (Geneseeq), aiming to comprehensively profile their concurrent mutation statuses and explore the potential resistance mechanisms in G724S-positive patients. (frontiersin.org)
A 47-year-old Chinese female patient without a smoking history was preliminarily diagnosed with right lung cancer with suspected multiple liver and bone metastasis. (frontiersin.org)
Our objective was to provide an updated analyses of the lung cancer cases from a multi-site international cohort study, including descriptive statistics of the demographics (age, sex, and race/ethnicity) of cases, as well the of histology. (biomedcentral.com)
We assessed the demographic characteristics for all lung cancer cases in the SLE patients, and information on histology types was analyzed from the centers where this information was available. (biomedcentral.com)
Our results suggest a similar distribution, but with a possibly lower proportion of adenocarcinomas, and a higher number of uncommon lung cancer types. (biomedcentral.com)

Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)

Currently, the molecular mechanism underlying epithelial metaplasia in BE patients remains unknown. (jcancer.org)
The region of columnar esophageal metaplasia is considered the "cancerization field" in which esophageal adenocarcinoma (EAC) develops [ 3 - 5 ]. (jcancer.org)

This randomized phase II/III trial studies how well pegylated liposomal doxorubicin hydrochloride with atezolizumab and/or bevacizumab work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back. (clinicaltrialsgps.com)
It is not yet known which combination will work better in treating patients with ovarian, fallopian tube, or primary peritoneal cancer. (clinicaltrialsgps.com)
Results Nine-hundred patients with primary ovarian cancer were reviewed, out of which 94 patients (10.4%) had MOC. (thieme-connect.de)
Paired samples of primary gastric cancer and corresponding para-cancerous, non-cancerous gastric mucosae were obtained from surgically resected specimens of 28 patients. (wjgnet.com)
In 5% of GCT patients, the primary site is at an extragonadal location [ 9 ]. (uroweb.org)

1 ] Mucinous ovarian cancer (MOC) is a rare subtype of malignant ovarian cancer. (thieme-connect.de)
Ovarian mesonephric-like adenocarcinoma (MLA) is a rare cancer subtype. (bvsalud.org)
The terms BAC and mixed subtype adenocarcinoma are no longer used. (qxmd.com)

Results In NAFLD patients, the platelet count was significantly higher at each grade of fibrosis in comparison to CLD-HCV. (go.jp)

and (3) other malignancies which are commonly developed in patients with appendiceal NETs. (wjgnet.com)
In a patient who had been diagnosed in 2006 with appendiceal adenocarcinoma with peritoneal metastases after an incomplete surgery, palliative chemotherapy was administered. (karger.com)

We describe a patient with ovarian MLA wherein liver metastases developed 1 month after surgery. (bvsalud.org)
In spite of that, the majority of patients are diagnosed with advanced disease (74%), equally locally or with distant metastases. (karger.com)
The PFS benefit was consistent in patients with and without baseline CNS metastases (HRs, 0.37 and 0.46, respectively). (memoinoncology.com)
In the alectinib group, patients showed higher event-free rates with respect to PFS regardless of the presence or absence of baseline CNS metastases. (memoinoncology.com)

Many studies now justify that AAH is a precursor to adenocarcinoma 4 - 14 . (ersjournals.com)
BE is known as a precursor of esophageal adenocarcinoma. (jcancer.org)

This new adenocarcinoma classification is needed to provide uniform terminology and diagnostic criteria, especially for bronchioloalveolar carcinoma (BAC), the overall approach to small nonresection cancer specimens, and for multidisciplinary strategic management of tissue for molecular and immunohistochemical studies. (qxmd.com)
Sp17 expression may have diagnostic significance in this subset of patients. (biomedcentral.com)
Particularly for early T stage patients, such as T1 and T2, oncologists or hepatobiliary surgeons may overlook the possibility of distant metastasis, resulting in insufficient preoperative diagnostic examinations, follow-up, and postoperative comprehensive treatment. (medsci.org)
Large scale multi-institutional and multiregional translational studies are required to generate molecular data that would inform diagnostic, prognostic, and risk-stratification guidelines for Saudi CRC patients. (org.sa)

Our multidisciplinary team is fully engaged in highly innovative translational research including first-in-human trials accelerate the development of therapeutic options available to CRC and PDAC patients. (cancer.gov)
5% of patients with microsatellite instability, 2) the slow pace of chemoprevention research and limited repertoire of agents being evaluated in the clinic for populations at-risk for CRC, and 3) necessity to explore novel therapeutic vulnerabilities and eliminate residual disease after standard of care therapy in PDAC. (cancer.gov)
Hereditary factors play a role in the development of PDAC in 3% to 5% of all patients. (medscape.com)

For resection specimens, new concepts are introduced such as adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) for small solitary adenocarcinomas with either pure lepidic growth (AIS) or predominant lepidic growth with ≤ 5 mm invasion (MIA) to define patients who, if they undergo complete resection, will have 100% or near 100% disease-specific survival, respectively. (qxmd.com)
As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)

The Japanese Gastric Cancer Treatment Guidelines ( Tokyo, Kanehara & CO. Ltd. (2021)">6 ) recommend postoperative adjuvant chemotherapy after curative surgery for patients with pathological stage II or III gastric cancer ( Surgery 158(6) (2015)">7 , Lancet Oncol 14(12) (2013)">8 ). (cancerdiagnosisprognosis.org)
All cases were pathologically diagnosed, and 177 patients were diagnosed with pT1N+ or pT2-3N0 gastric cancer based on the 15th Japanese Classification of Gastric Carcinoma ( Tokyo, Kanehara & CO. Ltd. (2017)">4 ). (cancerdiagnosisprognosis.org)

Epithelial tissue from both the rat BE model and human BE patients strongly expressed KLF5, CDX2, MUC2, and villin. (jcancer.org)

PARTICIPANTS: Individuals with histologically confirmed localized rectal/rectosigmoid adenocarcinoma. (elsevierpure.com)
We describe two cases of rectal herpes simplex virus (HSV) infection in men that clinically mimicked rectal adenocarcinoma. (hindawi.com)

[4] , [5] While squamous carcinoma remains overwhelmingly preponderant in the developing world, its frequency has slightly declined in the developed world, with relatively increased in the prevalence of adenocarcinoma. (smjonline.org)

The mucinous cystadenomas on the other hand, even though slow growing, have high chances of malignant transformation and hence need to be managed earlier, surgically [ 3 ]. (hindawi.com)

Conclusion: The colposcopy may be a good screening method with a good colpo-histology agreement in Cotonou. (scirp.org)

Objective To evaluate the clinicopathological features and survival outcomes of mucinous ovarian cancer (MOC) patients in an Asian population. (thieme-connect.de)
It is unknown whether patients with EOC have elevated serum Sp17 levels or if Sp17 expression is associated with survival outcomes. (biomedcentral.com)

The verdict is that the data on the molecular alterations in CRC from Saudi patients is at best modest. (org.sa)

Adenocarcinomas of the head of the pancreas cause obstructive jaundice (which can cause pruritus) in 80 to 90% of patients. (msdmanuals.com)

Children with long-standing gastroesophageal reflux disease (GERD) are at risk for developing Barrett esophagus , dysplasia, and adenocarcinoma in a progression similar to that seen in adults. (medscape.com)
High-grade dysplasia or adenocarcinoma of the esophagus requires esophagectomy and gastric pull-up or bowel interposition for reconstruction. (medscape.com)

A colposcopy biopsy was performed in 95 patients meaning 21.6% of patients. (scirp.org)
The patient's past medical history included a cerebrovascular accident with residual left-sided weakness, bronchial asthma, lung adenocarcinoma (stage IIIB) diagnosed by computed tomography (CT)-guided right upper lobe biopsy 5 months previously. (biomedcentral.com)

OBJECTIVE: To identify treatment-related factors associated with hospital margin-positive resection and to develop a tool that could be used by individual hospitals to assess their outcomes based on their unique mix of patient and tumor characteristics. (elsevierpure.com)
MAIN OUTCOMES AND MEASURES: Rate of margin positivity determined and adjusted for patient- and tumor-related factors to calculate expected margin positivity per hospital. (elsevierpure.com)
Objective We sought to describe clinicopathologic and treatment factors associated with oncologic outcomes in patients with early-stage ovarian clear cell carcinoma undergoing complete staging and in a sub-set of these patients undergoing fertility-conserving surgery. (bmj.com)

however, in 2009, an organization was started-the American Society of Peritoneal Surface Malignancies (ASPSM)—to improve the overall care of patients with peritoneal surface malignancies, and it set HIPEC standardization as its first goal. (oncnursingnews.com)

Forty (40) cases of Grade 1 Atypical Transformation, twenty-nine (29) cases of Grade 2 Atypical Transformation including two (2) cases of leukoplakia (1 post-conization for CINIII, 1 in a HIV+ patient), ten (10) cases of Grade 1 Atypical Transformation/Grade 2 Atypical Transformation association were recorded. (scirp.org)

It has been reported that the presence of Ex19del reduced osimertinib-binding affinity to EGFR in vitro ( 3 , 4 ), whereas it retained sensitivity to afatinib, suggesting a possible therapy for patients ( 3 ). (frontiersin.org)

We decided to maintain the treatment, although forced bevacizumab "breaks" were necessary due to unexpected adverse events, with the patient suffering disease progression every time bevacizumab was stopped and reaching minor response again once the antiangiogenic treatment was reintroduced. (karger.com)
Treated with afatinib combined with chemotherapy, both patients responded well and achieved progression-free survival. (frontiersin.org)
According to the public cases, five patients with Ex19del/G724S treated with afatinib monotherapy achieved an average of only four months of progression-free survival (PFS)(2). (frontiersin.org)

Every patient needs aggressive medical treatment. (medscape.com)
2 Patients may go on to receive systemic chemotherapy, particularly if they have more extensive or aggressive disease. (oncnursingnews.com)

Squamous carcinoma mostly occurred in a slightly older age group (fifth to seventh decades), than adenocarcinoma (fourth to sixth decades). (smjonline.org)

The specific objective of this proposal is to generate an effective, personalized vaccine approach for treatment of metastatic CRC patients at high risk of recurrence following surgery. (cancer.gov)
Specifically, we will test the hypothesis that a vaccination strategy targeting multiple mutated CRC tumor antigens along with specific combinations of immune adjuvants will be capable of preventing recurrence in minimal residual disease (MRD) setting in post-hepatectomy CRC patients. (cancer.gov)
Patients in the report had a 5-year overall survival rate of 93.1%, although survival rates were lower in children who experienced symptoms, local recurrence, or metastasis or who did not undergo treatment with surgery or surgery plus radiotherapy. (medscape.com)
However, some patients experience disease recurrence. (cancerdiagnosisprognosis.org)
Results: Thirteen patients (8.3%) experienced disease recurrence. (cancerdiagnosisprognosis.org)

Anatomy1

Organisms1

Diseases23

Chemicals and Drugs3

Analytical, Diagnostic and Therapeutic Techniques and Equipment4

Phenomena and Processes1

Disciplines and Occupations2

Health Care1

Tumors15

Neoplasms9

Case of mucinous adenocarcinoma2

Ductal7

Serous3

Prognosis7

Neoplasm1

Lesions4

Squamous cell carc1

Pancreatic5

Differentiated carcinoma1

Colorectal5

Diagnosis10

Incidence4

Cancers8

Clinical4

Endometrial Adenocarcinoma1

Underwent7

Pathology3

NSCLC6

METHODS5

Histological1

Signet1

Advanced-stage3

Carcinomas1

Malignancy1

Lung cancer14

Tumours1

Metaplasia2

Primary5

Subtype3

Significantly1

Appendiceal2

Metastases4

Precursor2

Diagnostic4

PDAC3

Invasive2

Gastric cancer2

Epithelial1

Rectal2

Prevalence1

Malignant1

Conclusion1

Survival outcomes2

Molecular1

Pancreas1

Dysplasia2

Biopsy2

Outcomes3

Peritoneal1

Grade1

EGFR1

Progression3

Aggressive2

Decades1

Recurrence5