Patients experiencing copd exacerbations. Medical search. Frequent questions

48 patients (23%), experienced one episode, 82 patients (40%) experienced 2 or more exacerbations, and 50 patients required hospitalization. (nih.gov)
Any amount of moderate to vigorous physical activity can effectively reduce the risk of dying after hospitalization for chronic obstructive pulmonary disease (COPD), according to a new study. (sciencedaily.com)
Objective - To determine the association between outpatient use of oral antibiotics and 30-day all-cause mortality following hospitalization in a group of elderly chronic obstructive pulmonary disease (COPD) patients. (ices.on.ca)
Conclusions - Use of antibiotics before hospitalization was associated with a significant reduction in the risk of short term mortality among a group of elderly COPD patients who eventually required hospitalization for their disease. (ices.on.ca)
PARIS - In patients with a chronic obstructive pulmonary disease ( COPD) exacerbation, initiating azithromycin at the time of hospitalization provided improvement in a variety of outcomes at 90 days, including risk of death, according to a placebo-controlled trial presented as a late-breaker at the annual congress of the European Respiratory Society. (the-hospitalist.org)
Ms. Langford Clinical question: Does the initiation of pulmonary rehabilitation after hospitalization for a chronic obstructive pulmonary disease (COPD) exacerbation impact. (the-hospitalist.org)
Data from patients with COPD (≥40 years), with a hospital-based COPD clinic visit between 2010-2016 (index date) and a hospitalization for CV events (stroke, myocardial infarction) or heart failure (HF) 36 to 6 months prior to index, were linked with nationwide Danish health registries, and followed for COPD exacerbations, CV events and death. (ersjournals.com)
COPD is a progressive life-threatening lung disease that causes breathlessness and predisposes patients to frequent attacks resulting in serious illness, hospitalization and even death. (technologynetworks.com)
Based on a 2023 revision of the GOLD Criteria, doctors will also consider three other factors: severity of symptoms and degree of impact on your life (assessed through questionnaires), frequency of acute exacerbations (when COPD gets suddenly worse) or hospitalization in the last year, and the presence and types of other diseases (known as multimorbidity). (everydayhealth.com)
6 Patients who survive hospitalization for sepsis are at increased risk for negative health outcomes including the development of new morbidity, inability to return to work, hospital readmission, and death. (cdc.gov)
Extended use of the common antibiotic azithromycin may prolong the time between hospitalizations for patients suffering from chronic obstructive pulmonary disease (COPD), according to a post-hoc analysis of a multicenter study which compared the hospitalization rates of patients treated with a 12-month course of azithromycin to the rates of those treated with placebo. (science20.com)
The researchers noted the time any patient had an initial respiratory-related hospitalization and then measured the time that elapsed before the same patient was re-hospitalized, keeping track of the total number of hospitalizations as well as those that were due to respiratory-related causes such as pneumonia, influenza, bronchitis, asthma or acute exacerbation of COPD. (science20.com)
Next, the researchers compared that elapsed time in patients treated with azithromycin with those receiving placebo, adjusting their comparison for differences in age, gender and health and lifestyle indicators, and found that patients treated with azithromycin had a longer period between their first respiratory related hospitalization and the next hospitalization compared to patients treated with placebo. (science20.com)
COPD patients who have been hospitalized for a respiratory event are at particularly high risk for re-hospitalization, and we wanted to examine whether chronic azithromycin therapy might provide a benefit in these patients. (science20.com)
When comparing patients treated with azithromycin and those who received placebo, we found that there was a significant delay from the first respiratory-related hospitalization to the next one among those treated with azithromycin. (science20.com)
Also, looking at re-hospitalization due to any cause, we found there was a trend toward a delay between first and subsequent all-cause hospitalizations for patients taking azithromycin compared to those that did not take it. (science20.com)
We can't keep patients in the hospital who don't need hospitalization," says Dr. Rooks, "but we have to keep the patients and families happy so that satisfaction scores are high. (todayshospitalist.com)
Severe exacerbations were defined as requiring hospitalization. (esciencenews.com)
Introduction: Patients with COPD experience exacerbations that may require hospitalization. (coventry.ac.uk)
To investigate a relationship between a 6-minute walk distance (6MWD) and a risk of hospitalization in patients with chronic obstructive pulmonary disease (COPD) in one year. (tci-thaijo.org)
The risk of hospitalization for exacerbation in one year was calculated and compared between the two groups. (tci-thaijo.org)
During the one year follow up period 31.7% of patients experienced hospitalization from exacerbation of COPD. (tci-thaijo.org)
350 meters had 6.6 times risk of hospitalization for treatment of acute COPD exacerbation in one year more than those with the 6MWD at least 350 meters. (tci-thaijo.org)
Respiratory viral infections occurring during COPD exacerbations are more likely to lead to hospitalization as a result of viral infections leading to a greater airway inflammation and therefore, more severe exacerbations. (spandidos-publications.com)

COPD exacerbations were defined by worsening symptoms requiring systemic corticosteroids and/or antibiotics (moderate) or hospital admission (severe). (ersjournals.com)
however, the benefit of LAMAs on COPD symptoms has been variable. (nature.com)
In recognition of the complexities of COPD, a large number of guideline-based therapies are available that aim to improve symptoms, reduce the frequency and severity of exacerbations, and improve health status and exercise tolerance. (nature.com)
5 The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 strategy now recommends that COPD management should consider both disease impact (i.e., assessment of symptoms) measured by the COPD Assessment Test (CAT) or modified Medical Research Council (mMRC) dyspnea scale, and exacerbation history. (nature.com)
6 Phase III trials have shown that glycopyrronium produces rapid and sustained improvements in lung function, symptoms, health status, exercise endurance and exacerbation risk in patients with COPD. (nature.com)
1 , 2 The symptoms they experience are frightening and unpleasant, 3 their quality of life is reduced 4 and the restriction in their physical activity, which may persist for weeks after the onset of symptoms, increases the risk that they will become housebound. (bmj.com)
Patients with COPD can be hospitalised if they experience an acute exacerbation of their symptoms. (sciencedaily.com)
1 2 It is heterogeneous, but many patients experience progressive airflow obstruction, exacerbations and/or persistent symptoms of dyspnoea, cough and sputum production. (bmj.com)
2 Exacerbations are heterogeneous and vaguely defined as acute worsening of respiratory symptoms outside of normal day-to-day variation, usually associated with a healthcare utilisation event (eg, prescription of oral steroids and/or antibiotics, emergency room visit). (bmj.com)
The Latin American Study of 24-h Symptoms in Chronic Obstructive Pulmonary Disease (LASSYC), a real-life study, evaluated the self-reported inhaler adherence in COPD patients in seven countries in a cross-sectional non-interventional study and found that approximately 50% of the patients had good adherence, 30% moderate adherence and 20% poor adherence. (mdpi.com)
If exacerbations can be identified before the symptoms appear, they can be dealt with earlier, limiting their effect and potential consequences. (technologynetworks.com)
Professor Chris Brightling, NIHR Senior Investigator, University of Leicester, commented: "This simple urine test will help COPD patients distinguish the beginning of a severe lung attack from, simply, a variation in their background symptoms which will get better on their own. (technologynetworks.com)
A combination inhaler can help control and prevent COPD symptoms. (everydayhealth.com)
Depending on your symptoms and number of exacerbations and hospitalizations, you would be placed in a group of A, B, C, or D. (everydayhealth.com)
Although maintenance therapies have improved the lives of patients with Chronic Obstructive Pulmonary Disease (COPD), some individuals on maintenance triple therapy for COPD still have symptoms or experience COPD exacerbations, which can result in a hospital admission. (clinicalconnection.com)
The PILLAR study is being conducted to investigate the safety, tolerability, and effectiveness of a new investigational add-on medication that may reduce airway inflammation and improve COPD symptoms in people on maintenance triple therapy. (clinicalconnection.com)
Sereflo could be considered for use in patients with moderate persistent asthma but only where control of symptoms cannot be maintained with a lower strength product containing a lower dose of the corticosteroid. (medicines.org.uk)
In the event of once daily dosing when the patient has a history of nocturnal symptoms the dose should be given at night and when the patient has a history of mainly daytime symptoms the dose should be given in the morning. (medicines.org.uk)
With COPD, you may be able to participate in the same activities for weeks or months without having worsening symptoms. (linkddl.com)
WebA COPD exacerbation, or flare-up, occurs when your COPD respiratory symptoms become much more severe. (linkddl.com)
An exacerbation (ex-zass-cer-bay-shun) of Chronic Obstructive Pulmonary Disease (COPD) is a worsening or "flare up" of your COPD symptoms. (linkddl.com)
Characterization of the patients is crucial and includes symptoms (questionnaires), lung function tests (spirometry, body plethysmography, diffusion capacity, and impulse oscillometry), imaging (Chest X-ray and computer tomography), 6 minute walk test, echocardiography and blood chemistry. (ki.se)
COPD is one of the respiratory diseases which requires palliation of symptoms, is known to have four stages within its disease trajectory beginning with mild, moderate and progressing to moderately severe (Currie, 2017). (ukessays.com)
Although COPD is a bracket name given to multiple lung conditions such as emphysema and chronic bronchitis the two conditions are very similar and often present with similar symptoms. (ukessays.com)
5 Symptoms such as chronic dyspnea and cough should prompt the clinician to consider a diagnosis of COPD. (reliasmedia.com)
8 Emergency visits relating to COPD are commonly due to acute exacerbations, characterized by a sudden worsening of symptoms. (reliasmedia.com)
In the current study, both groups experienced significant respiratory symptoms and impairment but did not lose lung function as a result of an acute respiratory event or exacerbation. (esciencenews.com)
Associated topics: breathing-/-inhale,respiratory-system - "Cineole has mucolytic, bronchodilating and anti-inflammatory properties and reduces the exacerbation rate in patients suffering from COPD, as well as ameliorates symptoms in patients suffering from asthma and rhinosinusitis. (oil-testimonials.com)
The COPD Assessment in Primary Care to Identify Undiagnosed Respiratory Disease & Exacerbation Risk (CAPTURE), developed with support from the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, was designed to identify adults with COPD symptoms severe enough to treat, but who haven't received a diagnosis(link is external). (news-line.com)
Common COPD symptoms include coughing, shortness of breath, wheezing or whistling in the chest, and chest tightness or heaviness. (news-line.com)
One benefit of the CAPTURE screening, the researchers said, is that it gives doctors information to further assess patients with respiratory symptoms. (news-line.com)
Patients with COPD experience some day-to-day change in respiratory symptoms. (owlstonemedical.com)
A larger than normal worsening of symptoms is known as an acute exacerbation of COPD (AECOPD) and is especially associated with worse clinical outcomes from reduced quality of life to significantly increased likelihood of death. (owlstonemedical.com)
In genetically susceptible individuals, these interactions can lead the patient with asthma to symptoms of breathlessness, wheezing, cough, and chest tightness. (medscape.com)

Hospitalisation and COPD-associated mortality account for substantial treatment and healthcare resource utilisation costs [ 2 - 4 ]. (ersjournals.com)
In patients with structurally normal hearts, atrial tachycardia is associated with a low mortality rate. (medscape.com)
[ 1 ] In this modern era of medical miracles, COPD is the only major cause of death in the United States for which both the mortality and morbidity rates are rising. (medscape.com)
Chronic obstructive pulmonary disease (COPD) is a highly prevalent respiratory disease and the leading cause of morbidity and mortality worldwide. (bmj.com)
Overall these patients have poorer health status, accelerated forced expiratory volume over 1 s (FEV1) decline, worsened quality of life, and increased hospital admissions and mortality, contributing to increased exacerbation susceptibility and perpetuation of the frequent exacerbator phenotype. (nih.gov)
The clinical trial Towards a Revolution in COPD Health (TORCH) study clearly showed in a three year follow up that patients with good adherence to their inhaler treatment presented a longer time before the first exacerbation, a lower susceptibility to exacerbation and lower all-cause mortality. (mdpi.com)
Another COPD assessment and prognosis tool used by doctors is the BODE index, which has been shown to help predict COPD mortality, or how long people have to live after being diagnosed with the disease. (everydayhealth.com)
In New Zealand, Māori, Pacific peoples, and those with lower socioeconomic status experience higher levels of chronic illness, which is the leading cause of mortality, morbidity and inequitable health outcomes. (biomedcentral.com)
Multiple randomized controlled trials and analyses of real-world data have shown that patients treated with NIV are less likely to require IMV and have better mortality and length of hospital stay. (hhs.gov)
Disposition from the emergency department is determined by the severity of the exacerbation, the response to treatment, and the presence of comorbidities that increase short-term mortality. (reliasmedia.com)
People with COPD frequently seek emergency care for acute exacerbations, which are associated with significant morbidity and mortality. (reliasmedia.com)
12 Exacerbations also are associated with higher mortality. (reliasmedia.com)
In a Spanish cohort of (predominantly male) patients prospectively followed, Guerrero et al demonstrated that re-admission to hospital within 30 days following discharge for an exacerbation of COPD increased 12 month mortality rates (37% in readmitted versus 17% in non-readmitted patients, p=0.001) and was an independent risk factor for mortality at one year (HR 2.48 95% CI 1.1-5.59) ( Guerrero 2016 ). (copdx.org.au)
Exacerbations of chronic obstructive pulmonary disease (COPD) contribute greatly to increased morbidity, mortality and diminished quality of life. (biomedcentral.com)
Chronic obstructive pulmonary disease (COPD), characterized by irreversible airflow obstruction, is one of the leading causes of morbidity, mortality and health-care costs in the United States. (biomedcentral.com)
COPD is increasing worldwide because of increases in smoking and reduction in mortality due to infectious diseases. (msdmanuals.com)
COPD) is an important and grow- was to estimate the prevalence of direct interviews with the study par- ing cause of morbidity and mortality COPD among a sample of adult smok- ticipants. (who.int)

COPD clinical trials primarily focus on bronchodilator response using minimal clinically important difference (MCID) to determine improvements in lung function and patient-reported outcomes. (nature.com)
Against this backdrop, it is vital that, as a clinical and research community, we should tenaciously pursue all opportunities to improve the experience for these patients. (bmj.com)
The results also demonstrate the importance of routinely assessing physical activity in clinical care to identify high-risk patients as part of a larger strategy to promote physical activity in this highly sedentary population. (sciencedaily.com)
The contribution of the microbiome to chronic obstructive pulmonary disease (COPD) pathobiology and the potential for microbiome-based clinical biomarkers in COPD are still in the early phases of investigation. (bmj.com)
Although the sputum microbiome likely reflects the respiratory microbiome only in part, there is increasing evidence that microbial community structure and diversity are associated with disease severity and clinical outcomes, both in stable COPD and during the exacerbations. (bmj.com)
Some patients experience frequent exacerbations, and are now recognized as a distinct clinical subgroup, the 'frequent exacerbator' phenotype. (nih.gov)
Mologic, a developer of lateral flow and rapid diagnostic technologies, has announced the launch of a major clinical trial to validate the Company's urine-based multi-biomarker self-test, Headstart®, for the early detection of exacerbations in patients living with moderate to severe chronic obstructive pulmonary disease (COPD). (technologynetworks.com)
Supported by a wide consortium of clinical experts, the observational trial known as COPE-WEL has recently started recruitment of 263 patients across 10 centres in the UK. (technologynetworks.com)
The COPE-WEL trial expands on a previous proof-of-concept study that successfully demonstrated the use of Headstart as a multi-biomarker diagnostic self-test with the ability to predict the early onset of a COPD exacerbation up to six days prior to symptom onset, or up to nine days prior for clinical diagnosis by a healthcare provider. (technologynetworks.com)
The Headstart system is designed for home monitoring and integrates a simple, easy to use diagnostic with a reader and mobile phone app to capture patient-specific health data, which are digitally transferred to care providers for monitoring and provide patients early warning of an exacerbation event, prior to clinical signs. (technologynetworks.com)
Limited treatment options for patients with mesothelioma means a short median survival time after diagnosis, and clinical management is hampered by the lack of molecular biomarkers for diagnosis or prognosis. (edu.au)
As patients can arrive at any time and with any complaint, a key part of the operation of an emergency department is the prioritization of cases based on clinical need. (wikipedia.org)
Most patients will be initially assessed at triage and then passed to another area of the department, or another area of the hospital, with their waiting time determined by their clinical need. (wikipedia.org)
The PILLAR Study: A Clinical Trial for Patients Diagnosed with Chronic Obstructive Pulmonary Disease (COPD) with an Inhaled Maintenance Triple Therapy. (clinicalconnection.com)
For their study, the researchers used clinical data gathered from a previous study of azithromycin use conducted by the COPD Clinical Research Network (CCRN), a group of research centers established to study new treatments for COPD and funded by the National Heart, Lung, and Blood Institute (NHLBI). (science20.com)
This collaboration will help us improve the clinical outcomes of our COPD patients by identifying the need for interventions early so we can avoid serious exacerbations, preserve their lung function and improve their quality of life. (ucdavis.edu)
The rescue use will be key in alerting clinicians that the patient may be experiencing early signs of a COPD exacerbation," explained Krystal Craddock, clinical operations manager for respiratory care. (ucdavis.edu)
There are so many patients in our community that could benefit from a program like this and improve their clinical outcomes," Kuhn added. (ucdavis.edu)
As a simple imaging procedure, lung ultrasound contributes to the early identification of patients with clinical conditions suggestive of COVID-19, supports decisions about hospital admission and informs therapeutic strategy. (journaltocs.ac.uk)
Over 100 free commonly used clinical formulas and calculator tools to help diagnose, treat, prevent, and determine prognosis of patients at point of care. (guidelinecentral.com)
Identify clinical preventive services that are appropriate for your patients. (guidelinecentral.com)
Background: The clinical guideline recommends use of long-acting ß2 agonists/long-acting muscarinic antagonists (LABA/LAMA) or long-acting ß2 agonists/inhaled corticosteroids (LABA/ICS) combination therapies for patients with severe chronic obstructive pulmonary disease (COPD). (bvsalud.org)
Exacerbations with clinical features of infection (increased volume and change in colour of sputum and/or fever) benefit from antibiotic therapy. (copdx.org.au)
After a multi-year-long clinical trial, researchers found CAPTURE successfully identified almost half of participants who had moderate to severe forms of previously undiagnosed COPD. (news-line.com)
For this purpose, Global Initiative for Asthma (GINA) recommendations underline the need to identify and handle the comorbidities as a key part of clinical practices for asthma patients [ 1 ] . (researchsquare.com)
We used the IQVIA general practitioner electronic medical record database to identify patients ≥50 years of age with a clinical diagnosis of pertussis during 2015-2019. (cdc.gov)
Clinical Experience with SERPINA1 DNA Sequencing to Detect Alpha-1 Antitrypsin Deficiency. (cdc.gov)

Doctors determine the best treatment plan for you based on the severity of your COPD. (everydayhealth.com)
Patients should be given the strength of Sereflo containing the appropriate fluticasone propionate dosage for the severity of their disease. (medicines.org.uk)
WebAcute exacerbations of COPD are generally characterized by increased dyspnea, increased frequency and severity of cough, and potentially increased sputum. (linkddl.com)
Participants were grouped by COPD severity based on Global Initiative for Chronic Obstructive Lung Disease, or GOLD, guidelines. (esciencenews.com)
Smokers without COPD with an acute respiratory event and those with PRISm with an exacerbation of any severity did not experience FEV1. (esciencenews.com)
Systemic corticosteroids reduce the severity of, and shorten recovery from exacerbations. (copdx.org.au)
Exacerbations become more frequent as severity of COPD worsens ( Hoogendoorn 2010a ). (copdx.org.au)
Diagnosis and spirometric assessment of the severity of COPD was performed according to the global initiative for chronic obstructive lung disease (GOLD) criteria ( 11 ). (spandidos-publications.com)
Survival in COPD is related to the severity of airflow limitation and the frequency of exacerbations. (msdmanuals.com)

5 In comparison with other medical emergencies, such as myocardial infarction and stroke, progress in improving the management of COPD exacerbations has been depressingly slow. (bmj.com)

Exclusion criteria have been described previously [ 21 ] and included long-term oxygen therapy at start of the study, or an exacerbation requiring systemic corticosteroids or hospitalisation during the run-in period. (ersjournals.com)
Rehospitalisation and death rates are high following any initial hospitalisation and in addition, hospitalisations due to severe exacerbations of COPD account for up to 70% of the healthcare costs associated with COPD. (sciencedaily.com)
The results found that patients who were active had a 47% lower risk of death in the 12 months following a COPD hospitalisation, compared to inactive patients. (sciencedaily.com)
The authors concluded that monitoring levels of physical activity with a simple exercise "vital sign," could help healthcare professionals identify, monitor and treat those patients at a high risk of death following hospitalisation. (sciencedaily.com)
Lead author, Dr Marilyn Moy, Assistant Professor at Harvard Medical School, commented: "We know that physical activity can have a positive benefit for people with COPD and these findings confirm that it may reduce the risk of dying following hospitalisation for an acute exacerbation. (sciencedaily.com)
ECLIPSE data also showed that a history of prior hospitalisation for COPD is the strongest predictor of subsequent hospitalisation. (copdx.org.au)
Purpose: While asthma comorbidities are associated with higher health care utilisation, lower quality of life and poorer asthma control, the impact of asthma comorbidities on hospitalisation for asthma exacerbation (H-AX) remains less recognised. (researchsquare.com)
Using data from a national survey on asthma control and disease perception, we aimed to analysis the impact of comorbidities on hospitalisation for asthma exacerbation (H-AX) in China. (researchsquare.com)

Chronic obstructive pulmonary disease , or COPD, is an umbrella term for a group of lung diseases that includes chronic bronchitis and emphysema . (everydayhealth.com)
COPD describes a group of diseases that include emphysema and chronic bronchitis. (ucdavis.edu)
This leads to the consequence that COPD patients differ in particular with regard to emphysema, bronchitis, bronchiolitis, reversibility of bronchodilators rate of exacerbations and systemic involvement. (ki.se)
The poorest survival was among older patients with recognised emphysema. (copdx.org.au)
In the current national immunization program (NIP) patients under the age of 70 years with COPD and chronic emphysema are not included in the risk conditions for National Immunisation Program (NIP) funded pneumococcal vaccination. (copdx.org.au)

These data come from studies of differing size and duration of follow-up that reported annualised exacerbation rates. (ersjournals.com)

A subsequent smaller study randomized patients with acute COPD exacerbations to placebo vs 30 mg prednisolone x 14 days. (medscape.com)
These 2 small studies support the use of corticosteroids in the treatment of acute COPD exacerbations. (medscape.com)

Patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) experience on average, two to three exacerbation episodes per year [ 1 , 2 ]. (ersjournals.com)
Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition comprising multiple pulmonary and extra-pulmonary manifestations. (nature.com)
In the March issue of the BCMJ, we began our two-part theme issue on chronic obstructive pulmonary disease (COPD) with articles describing COPD in BC and Canada, pharmacological ap-proaches to patients with stable COPD, nonpharmacological management of COPD, and the physiology of the disease. (bcmj.org)
Dr Sin (see page 152) provides a practical guide for general practitioners who must assist their patients in avoiding postoperative pulmonary complications. (bcmj.org)
Chronic obstructive pulmonary disease (COPD) is the most common underlying disease process (60%) in MAT. (medscape.com)
It seems to be common practice to use very large doses of intravenous (IV) corticosteroids (1-2 mg/kg of methylprednisolone every 6 hours) for a chronic obstructive pulmonary disease (COPD) exacerbation severe enough to require hospital admission. (medscape.com)
The best evidence supporting the use of systemic corticosteroid use for patients hospitalized with COPD exacerbation came from the Systemic Corticosteroids in Chronic Obstructive Pulmonary Disease Exacerbations (SCCOPE) trial. (medscape.com)
Patients with Chronic Obstructive Pulmonary Disease (COPD) have an increased risk of cardiovascular disease (CVD). (ersjournals.com)
Exacerbations of chronic obstructive pulmonary disease (COPD) are important events that carry significant consequences for patients. (nih.gov)
It has been shown that the better outcomes of chronic obstructive pulmonary disease (COPD) are closely associated with adherence to drug therapy, independent of the treatment administered. (mdpi.com)
Is stratification testing for treatment of chronic obstructive pulmonary disease exacerbations cost-effective in primary care? (ox.ac.uk)
Over 65 million people globally have moderate to severe Chronic Obstructive Pulmonary Disease (COPD). (clinicalconnection.com)
Preventing respiratory-related re-hospitalizations is a key component of COPD therapy, and previous research has shown that a 12-month course of azithromycin decreases the risk of acute exacerbations of COPD," said lead author Fernando Martinez, MD, MS, director of pulmonary diagnostic services at the University of Michigan Health System. (science20.com)
UC Davis Health and Propeller Health have announced a new collaboration that will offer personalized treatment for high-risk patients with asthma and chronic obstructive pulmonary disease (COPD). (ucdavis.edu)
WebMay 29, 2020 · Causes Treatment Prevention FAQ Takeaway Chronic obstructive pulmonary disease (COPD) is a persistent respiratory disease that may cause long-term, progressive lung damage. (linkddl.com)
Chronic obstructive pulmonary disease, or COPD, is a group of diseases that cause airflow blockage and extreme breathing problems to the point of breathlessness. (linkddl.com)
It will prioritise this health need with a specific focus on a holistic approach to nursing assessment, when assessing patients with Chronic Obstructive Pulmonary Disease, known as COPD. (ukessays.com)
Understanding the breadth of patients' support needs is important for the delivery of person-cantered care, particularly in progressive long-term conditions such as chronic obstructive pulmonary disease (COPD). (ukessays.com)
The most common cause of chronic obstructive pulmonary disease exacerbations is respiratory infections. (reliasmedia.com)
Chronic obstructive pulmonary disease (COPD) is a significant global health problem. (reliasmedia.com)
Acute exacerbations of chronic obstructive pulmonary disease, or COPD, are associated with significant long-term lung function loss, according to research published online, ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine . (esciencenews.com)
BACKGROUND: Use of combinations of long-acting ß2 agonists/long-acting muscarinic antagonists (LABA/LAMA) in patients with chronic obstructive pulmonary disease (COPD) is increasing. (bvsalud.org)
Consider pulmonary rehabilitation at any time, including during the recovery phase following an exacerbation. (copdx.org.au)
A new tool shows promise in helping primary care physicians identify adults with undiagnosed chronic obstructive pulmonary disease (COPD), according to research published in JAMA. (news-line.com)
The goal with trying to find COPD is to treat it earlier, which will help make patients feel better and hopefully prevent their disease from progressing," said Fernando J. Martinez, M.D., a principal investigator of the study and chief of the Pulmonary and Critical Care Medicine division at Weill Cornell Medicine, New York City. (news-line.com)
Directly measured physical activity as a predictor of hospitalizations in patients with chronic obstructive pulmonary disease. (tci-thaijo.org)
9. Kundu A, Marji A, Sarkar S, Saha K, Jash D, Maikap M. Correlation of six minute walk test with spirometric indices in chronic obstructive pulmonary disease patients: a tertiary care hospital experience. (tci-thaijo.org)
Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease. (tci-thaijo.org)
Latent infection with adenovirus and respiratory syncytial virus (RSV) is associated with chronic obstructive pulmonary disease (COPD). (spandidos-publications.com)
Chronic obstructive pulmonary disease (COPD) is an inflammatory airway disease characterized by exacerbations, which are primarily caused by bacterial or viral infections. (spandidos-publications.com)
They make it through the vocal cords and into the large airways, so those particles can exacerbate asthma and chronic obstructive pulmonary disease (COPD). (medscape.com)
Chronic obstructive pulmonary disease (COPD) is airflow limitation caused by an inflammatory response to inhaled toxins, often cigarette smoke. (msdmanuals.com)
This longitudinal, retrospective, observational study aimed to estimate the incidence and risk factors of pertussis among persons ≥50 years of age in Australia in the primary care setting, including those with underlying chronic obstructive pulmonary disease (COPD) or asthma. (cdc.gov)
Patients with underlying respiratory conditions, such as asthma and chronic obstructive pulmonary disease (COPD), have an increased risk for pertussis, leading to more severe outcomes and exacerbation of asthma and COPD ( 8 - 10 ). (cdc.gov)
Success led to its adoption in other conditions, and noninvasive ventilation became especially promising in the treatment of patients with decompensated chronic obstructive pulmonary disease . (medscape.com)
Patient with an exacerbation of chronic obstructive pulmonary disease (COPD) undergoing treatment with noninvasive ventilation using an orofacial mask. (medscape.com)
ABSTRACT This cross-sectional study was conducted to estimate the prevalence and identify determinants of chronic obstructive pulmonary disease (COPD) among a convenience sample of 325 adult smokers in Baghdad, Iraq, 2014. (who.int)
Other types of respiratory diseases potentially impacted by workplace exposures include chronic obstructive pulmonary disease (or COPD), hypersensitivity pneumonitis, silicosis, lung cancer, and bronchiolitis obliterans. (cdc.gov)

Hospital Sepsis Program Core Elements are essential to optimize patient care and help clinicians, hospitals, and health systems in efforts to improve the hospital management and outcomes of sepsis. (cdc.gov)
The development of a multi-disciplinary hospital sepsis program is critical to monitoring and improving the management and outcomes of patients with sepsis. (cdc.gov)
Regardless of the structure of the hospital sepsis program, it should help healthcare staff improve outcomes from sepsis by aiding in the recognition of sepsis, facilitating the implementation of evidence-based management of sepsis, supporting the recovery of patients after sepsis, and monitoring the impact of hospital-based interventions to improve care and outcomes of sepsis. (cdc.gov)
A miniaturized sensor device could even allow precision monitoring of COPD patients in the home, detecting exacerbations in time for earlier intervention and improved outcomes. (owlstonemedical.com)

COPD exacerbations and hospitalisations were more frequent in winter. (ersjournals.com)
Frequent exacerbations are associated with a faster decline in FEV(1), impaired health status, and worse survival. (nih.gov)
9,10 Patients with a history of myocardial infarction and heart failure tend to have more frequent exacerbations. (reliasmedia.com)
EXACERBATIONS of COPD which are more frequent in the winter months in temperate climates ( Jenkins 2012 ) [evidence level II] often require hospital admission for treatment of respiratory failure. (copdx.org.au)
In the study by the ECLIPSE investigators, exacerbation rate increased with increasing GOLD stage, such that 22% of patients with GOLD stage 2 disease had two or more exacerbations during one year of follow-up, whereas 47% of patients with GOLD stage 4 disease had frequent exacerbations over the same period. (copdx.org.au)
In addition to a history of past exacerbations, Han reported that interleukin-15 (IL-15) and interleukin 8 (IL-8) levels in blood as well as small airway abnormalities on CT chest predicted frequent exacerbations ( Han 2017 ). (copdx.org.au)
Besides these, having uncontrolled asthma is inherently related to frequent exacerbations [ 11 ] . (researchsquare.com)

Overall, 38% of exacerbations were treated with antibiotics only, 19% with systemic corticosteroids only and 43% with both, while 20% required hospital admission irrespective of the season. (ersjournals.com)
In this issue, Drs Al Lawati and FitzGerald (see page 138) outline ways that systemic corticosteroids, antibiotics, and, in hypercapnic individuals, noninvasive mechanical ventilation can accelerate recovery from exacerbations. (bcmj.org)
Recommended Dose of IV Corticosteroids for COPD Exacerbation? (medscape.com)
Having been involved recently with 2 nondiabetic patients who experienced disseminated mucormycosis following treatment, I want to know whether there is any evidence base to determine the ideal inpatient dose of IV corticosteroids. (medscape.com)
For such a commonly encountered disease, there is a surprisingly small amount of evidence surrounding the use of corticosteroids in the management of acute exacerbation of COPD. (medscape.com)
[ 5 ] For decades, clinicians have prescribed corticosteroids for the treatment of acute COPD exacerbation, as an extension of the role of these medications in the treatment of acute asthma. (medscape.com)
[ 10 ] In this study, patients were randomized into 3 groups: placebo, a 2-week course of systemic corticosteroids, or an 8-week course of corticosteroid treatment. (medscape.com)
But this is insufficient evidence for suggesting an optimal dose of corticosteroids when treating an acute exacerbation. (medscape.com)

Severe exacerbations were associated with increased odds of CV events, which in the majority of patients occurred within 30 days after an exacerbation. (ersjournals.com)

Asthma exacerbations, especially those necessitating hospital admissions, contribute to the majority of the healthcare expenses in asthma patients [ 2 ] . (researchsquare.com)
Nevertheless, the role of comorbidities on asthma exacerbations remains less recognised, particularly, in a huge population of Chinese patients. (researchsquare.com)
Alpha-1 antitrypsin deficiency and Pi*S and Pi*Z SERPINA1 variants are associated with asthma exacerbations. (cdc.gov)

Outpatients aged 40-80 yrs with a diagnosis of COPD, defined in accordance with the European Respiratory Society (ERS) consensus statement [ 22 ], who were current or ex-smokers with ≥10 pack-yrs smoking history were recruited. (ersjournals.com)
Methods - All elderly patients admitted at least once with a most responsible diagnosis of COPD using the Canadian Institute for Health Information database were identified. (ices.on.ca)
A COPD diagnosis means you may have one or both of these lung-damaging diseases. (everydayhealth.com)
The diagnosis and treatment of infection in exacerbations and the management of stable COPD are discussed separately. (linkddl.com)
This review article addresses the role of lung ultrasound in patients with coronavirus disease 2019 (COVID-19) for diagnosis and disease management. (journaltocs.ac.uk)
Early diagnosis and treatment of exacerbations may prevent hospital admission and delay COPD progression. (copdx.org.au)
About 10% of patients with a primary diagnosis of COPD died either during admission or within the same year. (copdx.org.au)
If a non-invasive biomarker could be identified on exhaled breath, capable of differentiating between COPD and AECOPD, it would make diagnosis significantly easier and more accurate, while improving patients' quality of life and reducing unnecessary healthcare spending. (owlstonemedical.com)
For those with newly diagnosed COPD who have never received pneumococcal immunisation: a first dose of 13vPCV (conjugated vaccine) is recommended at diagnosis followed by up to two additional doses of 23vPPV regardless of age. (copdx.org.au)
Pocket guide to COPD diagnosis, management and prevention [Internet]. (tci-thaijo.org)
In the US, about 24 million people have airflow limitation, of whom about 16 million have a diagnosis of COPD. (msdmanuals.com)
Our findings suggest that persons ≥50 years of age in Australia with COPD or asthma have a higher incidence of and risk for pertussis diagnosis. (cdc.gov)

WebSep 19, 2023 · The management of patients with exacerbations of COPD is discussed here. (linkddl.com)

COPD was responsible for an estimated 923,000 emergency department (ED) visits in 2017, the most recent year for which data are available. (reliasmedia.com)
METHODS: We identified patients with COPD who initiated LABA/LAMA FDC or LABA/ICS FDC from a nationwide Taiwanese database during 2017-2020. (bvsalud.org)
Han et al prospectively examined exacerbation rates in 1,105 patients with COPD over a three-year period from the SPIROMICS cohort ( Han 2017 ). (copdx.org.au)
Patients with COPD who had a 6-minute walk test (6MWT) done at outpatient rehabilitation clinic between 1st July 2017- 30th April 2018. (tci-thaijo.org)

Drs Gan and Man (see page 148) remind us of the importance of evaluating comorbidities in COPD patients. (bcmj.org)
These comorbidities severely impair our patients' health status and must be treated aggressively. (bcmj.org)
Comorbidities are common among patients with COPD. (reliasmedia.com)
Results: Among 3875 ambulatory asthma patients, 75.9% (2941/3875) had comorbidities, and 26.4% (1017/3858) experienced H-AX during past year. (researchsquare.com)
Conclusions: Comorbidities such as COPD, coronary heart disease and allergic rhinitis, may have an important role in the risk and/or frequency of annual hospitalisations due to asthma exacerbation. (researchsquare.com)

Sputum is an easily obtainable sample and has provided a wealth of information on COPD pathobiology, and thus has been a preferred sample type for microbiome studies. (bmj.com)
This review provides an overview of the basic principles of high-throughput microbiome sequencing techniques, current literature on sputum microbiome profiling in COPD, and a discussion of the associated limitations and future perspectives. (bmj.com)
Does sputum, biochemical and radiological markers of infection correlate with antibiotic prescribing in acute exacerbations of COPD? (ers-education.org)
A COPD exacerbation is characterised by a change in the patient's baseline dyspnoea, cough, and/or sputum that is beyond normal day-to-day variations, is acute in onset, and may warrant a change in regular medication or hospital admission. (copdx.org.au)
Induced sputum, sera and nasal smears were sampled from patients experiencing COPD‑AE and those in a stable condition. (spandidos-publications.com)
The results showed that three sputum samples were positive for adenovirus in patients experiencing an exacerbation, while one was positive among the patients in a stable condition. (spandidos-publications.com)

In the study, 301 COPD patients hospitalized with an acute exacerbation were randomized within 48 hours of admission to azithromycin or placebo. (the-hospitalist.org)
The trend, after all, is being driven by payers looking for a less expensive way to evaluate patients who show up at the hospital but are not necessarily sick enough to warrant an admission. (todayshospitalist.com)
A record linkage study in WA ( Geelhoed 2007 ) demonstrated that the rate of hospital admission for COPD has been declining. (copdx.org.au)
An ecological study of hospital admissions for COPD in Victoria found higher rates of admission in rural and remote areas with greater socioeconomic disadvantage and higher rates of smoking ( Ansari 2007 ). (copdx.org.au)
Demographic data, 6MWD and number of admission for acute COPD exacerbation were extracted from the selected medical records. (tci-thaijo.org)

There is evidence of a seasonal variation in the rate of hospital admissions for COPD, with more exacerbations occurring during the winter months compared with summer [ 11 - 13 ]. (ersjournals.com)
Hospital admissions for exacerbations are major events in the lives of people with COPD. (bmj.com)
Recent studies report moderately strong positive associations between exposures to several air pollutants and COPD-related emergency department (ED) visits and hospital admissions (HA). (biomedcentral.com)

Factors predicting the frequency and slow resolution of exacerbations include increasing age, more severe airflow obstruction and a history of prior exacerbations [ 7 - 10 ]. (ersjournals.com)
COPD is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. (clinicalconnection.com)
COPD, as its name suggests, is defined by a chronic impediment to airflow through the bronchial tree. (reliasmedia.com)

Glycopyrronium is a once-daily LAMA indicated for the maintenance treatment of patients with COPD. (nature.com)
These patients are therefore a priority for research and treatment. (nih.gov)
As part of Mologic's flagship respiratory programme, validation of the Headstart system will provide patients with a transformative approach to tailoring remote disease management and early treatment. (technologynetworks.com)
Due to the unplanned nature of patient attendance, the department must provide initial treatment for a broad spectrum of illnesses and injuries, some of which may be life-threatening and require immediate attention. (wikipedia.org)
However, some patients may complete their treatment at the triage stage, for instance, if the condition is very minor and can be treated quickly, if only advice is required, or if the emergency department is not a suitable point of care for the patient. (wikipedia.org)
Patients who exhibit signs of being seriously ill but are not in immediate danger of life or limb will be triaged to "acute care" or "majors", where they will be seen by a physician and receive a more thorough assessment and treatment. (wikipedia.org)
This study evaluated the potential cost and effectiveness of RightStart testing (under development), which aims to guide treatment selections for COPD exacerbations in the primary care setting, using early-stage decision analytical modelling. (ox.ac.uk)
WebAn exacerbation is a flare-up or episode when your breathing is worse than usual and may continue to worsen without treatment. (linkddl.com)
COPD may continue to get worse despite treatment, eventually having a significant impact on their quality of life and leading to life limiting prognosis. (ukessays.com)
NIV is recommended in all COPD guidelines as the first-line treatment for patients with severe exacerbation who have failed pharmacologic treatment. (hhs.gov)
Through a series of mixed-methods studies we and other investigators have found that successful implementation of NIV requires physicians, respiratory therapists (RTs), and nurses to communicate and collaborate effectively to select appropriate patients for treatment, and to carefully manage patients after NIV initiation. (hhs.gov)
CONCLUSION: Our findings provide important reassurance about comparative cardiovascular safety of LABA/LAMA FDC treatment among patients with COPD. (bvsalud.org)
Inhaled bronchodilators are effective for initial treatment of exacerbations. (copdx.org.au)

Conclusion: This real-world study found evident temporal trends, variations in healthcare provider, and differences in patient characteristics among COPD patients who initiated LABA/LAMA FDC or LABA/ICS FDC. (bvsalud.org)

investigated the diagnostic potential of breath VOCs to detect AECOPD in contrast to clinically stable COPD patients. (owlstonemedical.com)
Stable COPD patients were recruited during routine check-ups where no acute exacerbation or infection was detected. (owlstonemedical.com)
The present study aimed to investigate the prevalence of adenovirus and RSV serotypes A and B in individuals with acute exacerbations of COPD (COPD‑AE) and stable COPD. (spandidos-publications.com)
Eighteen patients who experienced a COPD‑AE were also evaluated while in a stable condition. (spandidos-publications.com)
RSV serotype A was detected in 17/27 (63%) patients with COPD‑AE and 10/18 (55.6%) patients in a stable condition. (spandidos-publications.com)
Eight/ten patients who were positive for RSV serotype A while in a stable condition, were also positive during COPD‑AE. (spandidos-publications.com)
The results of the present study suggested that RSV infection may be prevalent in patients with COPD‑AE and in those in a stable condition. (spandidos-publications.com)
The aim of the present study was to investigate the prevalence of adenovirus and RSV A and B among patients with COPD-AE and those in a stable condition. (spandidos-publications.com)
The present study evaluated the association between viral infections, functional status and systemic inflammation in patients experiencing COPD-AEs and those in a stable condition. (spandidos-publications.com)

McKeever et al took a step back and asked the important question of whether, in fact, an arterial blood sample is always needed in the initial assessment of patients with COPD exacerbations. (bmj.com)
In addition to providing careful assessment of patients' dietary, exercise, and medication regimens, a multidisciplinary team can empower patients to take ownership of their disease through education, awareness, and self-management plans. (bcmj.org)
Triage is normally the first stage the patient passes through, and consists of a brief assessment, including a set of vital signs, and the assignment of a "chief complaint" (e.g. chest pain, abdominal pain, difficulty breathing, etc. (wikipedia.org)

The aim was to investigate the association between COPD exacerbations and severe acute cardiovascular (CV) events in COPD patients with a history of CVD. (ersjournals.com)

Studies that use clinically defined exacerbations rather than counting ED visits and HA may be more sensitive to environmental triggers like air pollution, but very few such studies exist. (biomedcentral.com)

This will ensure that the patient knows what to expect and that the patient's wishes can be respected during periods of medical crisis. (bcmj.org)
Digital health devices and platforms are helping improve care for patients with chronic conditions, like COPD, by providing clinicians a more expansive view of our patient's disease management," said Brooks Kuhn , assistant professor of medicine and co-director of the Comprehensive COPD Clinic . (ucdavis.edu)
11 Even one exacerbation is associated with some deterioration in a patient's respiratory status. (reliasmedia.com)

The BODE index is a sensitive tool used to assess the impact of exacerbations and to monitor COPD disease progression. (nih.gov)
COPD is a progressive disease in which many patients develop an acute or sustained deterioration. (nature.com)
COPD patients frequently have heart disease, osteoporosis, cachexia, and depression as result of or in conjunction with their COPD. (bcmj.org)
Thus, end-of-life issues should be discussed with patients, especially those with very advanced disease, preferably before they face a life-and-death crisis. (bcmj.org)
COPD is no longer an untreatable disease. (bcmj.org)
Patients with underlying structural heart disease, congenital heart disease, or lung disease are less likely to be able to tolerate this rhythm disturbance. (medscape.com)
To be fair, it is sometimes difficult to determine whether a given patient with obstructive lung disease has either asthma and/or COPD. (medscape.com)
Identifying COPD exacerbations and intervening early with an individualized or precision medicine strategy offers patients and clinicians a very promising approach to disease management, and could be transformative for the care of people with COPD. (technologynetworks.com)
The GOLD Criteria is the standardized way that COPD is assessed and classified and includes recommendations on how doctors should manage different stages of the disease. (everydayhealth.com)
As an alternative, patients requiring a long- acting β 2 agonist could be titrated to salmeterol and fluticasone propionate given once daily in the opinion of the prescriber, it would be adequate to maintain disease control. (medicines.org.uk)
According to the Centers for Disease Control and Prevention , 16 million Americans suffer from COPD. (ucdavis.edu)
COPD is a disease with a prevalence of 10% and is increasing with age. (ki.se)
Specifically, the prevalence of coronary artery disease among those with COPD is estimated to be as high as 33%, and approximately 24% have concomitant heart failure. (reliasmedia.com)
A history of exacerbations predicts future exacerbations, with exacerbation frequency increasing in patients with more severe disease. (reliasmedia.com)
Very early on in this disease -- at a time when outside a study like ours the majority of people would not have been diagnosed with COPD -- patients appear to be losing lung function," said lead author Mark T. Dransfield, MD, medical director of the University of Alabama at Birmingham Lung Center. (esciencenews.com)
The whole medical community is focused on the latter stages of COPD, when, like diabetes and heart disease and other chronic diseases, we should probably be focused on preventing morbidity much earlier. (esciencenews.com)
In that study steered with approval by the Ethics Committee of China Japan Friendship Hospital, data on demography, asthma control, medical and self- management, exacerbations, and disease perception were collected during face-to-face interviews with written informed consent from the patients. (researchsquare.com)
Participants in a COPD disease management group living in an area of low air pollution and who were followed closely for the earliest signs of an exacerbation provided an opportunity to study associations between air pollution and COPD exacerbation. (biomedcentral.com)
The additive effect of pneumococcal immunisation to annual influenza immunisation has been studied in a randomised, controlled trial over two years in Japanese patients with chronic lung disease ( Furumoto 2008 ). (copdx.org.au)
That PM2.5 is associated with exacerbations of preexisting heart disease and death due to cardiovascular disease, either myocardial infarctions or strokes. (medscape.com)
[ 3 ] In Western countries, the financial burden on patients ranges from $300 to $1,300 per patient year, increasing with more severe disease. (medscape.com)
more than half of all expenditures are attributed to the 10-20% of patients with the most severe disease. (medscape.com)
The WHO Global ers in Baghdad and to identify certain on sociodemographic data: age, sex, Burden of Disease Project estimated determinants underlying its develop- residence, occupation, education, and that COPD was the fifth leading cause ment. (who.int)

The OR of a fatal CV event was 1.4 (95% CI: 0.6-3.5) and 3.9 (95% CI: 1.6-9.1) after a moderate and severe exacerbation, respectively. (ersjournals.com)

We will then be able to reach out to these patients and treat them early, hopefully avoiding unnecessary emergency room visits or hospitalizations. (ucdavis.edu)
PROJECT SUMMARY COPD is the fourth leading cause of death in the US, and COPD exacerbations result in approximately 700,000 hospitalizations annually. (hhs.gov)

Methods: We identified COPD patients who initiated LABA/LAMA FDC or LABA/ICS FDC between 2015 and 2018 from a population-based Taiwanese database with 2 million, randomly sampled beneficiaries enrolled in a single-payer health insurance system. (bvsalud.org)
Methods: This is a prospective, single-blinded, two-center trial (ISRCTN84599369) with participants admitted for an exacerbation, randomized to usual care or SPACE for COPD. (coventry.ac.uk)
More invasive methods of investigating bronchial inflammation are not as sensitive as might be expected, complicated by the inflammatory background of COPD patients, and not practical for routine use with this patient group. (owlstonemedical.com)

The authors of this JAMA article examined the relationship between a broad set of 29 patient variables not included in the current CMS risk adjustment calculations and survey data for all-cause readmissions using Health and Retirement Study and Medicare data sets. (copdfoundation.org)
The current analysis was designed to test the impact of seasonal variation on reported exacerbations in relation to other risk factors, using data from the prospective, 3-yr Towards a Revolution in COPD Health (TORCH) study involving 6,112 patients from the northern and southern regions and the tropics [ 21 ]. (ersjournals.com)
It is crucial that healthcare professionals can identify patients at a high-risk of readmission. (sciencedaily.com)
Patients who were active but at insufficient levels still maintained a 28% lower risk of death, compared to inactive patients. (sciencedaily.com)
This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients. (nih.gov)
What Are the Causes and Risk Factors of COPD? (everydayhealth.com)
Long-term exposure to lung irritants - including secondhand smoke , air pollution, and chemical fumes or dusts from the environment or workplace - can also put you at risk of developing COPD. (everydayhealth.com)
In 2022, the Comprehensive COPD Clinic created the first remote patient monitoring program in the Sacramento region for high-risk patients with COPD. (ucdavis.edu)
Two years ago, patients who came in with diabetes, hypertension, hyperlipidemia and a family history and who presented with atypical chest pain would be an inpatient slam-dunk," explains James Rooks, MD, director of hospital medicine at the St. John Health System in Tulsa, Okla. "Now, even patients with multiple risk factors are being admitted under observation status. (todayshospitalist.com)
Because those with mild COPD appear to have the greatest loss of lung function following an exacerbation, the authors wrote, preventing exacerbations in this group "could reduce the risk of developing severe COPD. (esciencenews.com)
The risk of readmission was highest within three months of discharge and more than half of all patients were readmitted within 12 months. (copdx.org.au)
We found that short-term exposures to SO 2 were associated with an increase in COPD exacerbation risk (odds ratio (OR) = 2.45, 95 % CI: 1.75-3.45 per 1 ppb increase) after adjustment for PM 2.5 . (biomedcentral.com)
Despite living in an area with air pollution concentrations below current USEPA NAAQS, these COPD patients appeared to suffer increased risk of COPD exacerbation following short-term exposures to increased concentrations of SO 2 and NO 2 . (biomedcentral.com)
Well known risk factors for these acute exacerbations include bacterial and viral infections, as well as exposures to tobacco [ 2 ] and some workplace dusts and fumes [ 1 ]. (biomedcentral.com)
350 meters had a higher risk of being admitted to the hospital due to acute exacerbation of COPD than that of the group with 6MWD ≥ 350 meters. (tci-thaijo.org)
Patients with COPD or asthma had higher incidence rates and an increased risk for pertussis compared with the overall population ≥50 years of age. (cdc.gov)

The role of respiratory viral infections are emerging in COPD exacerbations. (spandidos-publications.com)

Headstart is an in vitro diagnostic self-test that detects five biomarkers indicative of infection and inflammation in the urine of COPD patients. (technologynetworks.com)
In many cases an exacerbation is caused by an infection in the lungs, but in some cases, the cause is never known. (linkddl.com)
However, physical proximity between the patient and the ultrasound operator is a limitation in the current pandemic context, emphasising the need to implement specific infection prevention and control measures.Availability of qualified staff adequately trained to perform lung ultrasound remains a major barrier to lung ultrasound utilisation. (journaltocs.ac.uk)
Therefore, chronic RSV infection may occur in COPD. (spandidos-publications.com)
However, chronic adenovirus and RSV infection data are currently unclear and, to the best of our knowledge, few longitudinal studies have been conducted on the association between chronic infection and COPD. (spandidos-publications.com)
Furthermore, RSV chronic infection in COPD and its consequences for local and systemic infection, and functional status have yet to be fully elucidated. (spandidos-publications.com)

Non-invasive ventilation improves survival for people with COPD and acute hypercapnic respiratory failure. (copdx.org.au)

Their study benefits from having recruited a realistic cohort of patients with COPD exacerbations, in sufficient numbers to produce quite precise estimates of the strength of agreement between the variables of interest. (bmj.com)
was greatest in the cohort of patients in the SCCOPE trial who received IV methylprednisolone. (medscape.com)

Can You Stop the Progression of COPD? (everydayhealth.com)

In a cohort of 40 COPD-patients, 40 smokers with normal lung function and 40 neversmokers (Karolinska COSMIC study) we have made significant attempts, by performing bronchoscopy, to characterize inflammation and structural changes in various levels in the airways as well as in the systemic circulation. (ki.se)
In " Acute Exacerbations and Lung Function Loss in Smokers with and without COPD ," the researchers reported that the greatest lung function loss occurred among those with mild COPD , and following severe exacerbations. (esciencenews.com)
Dr. Dransfield cautioned that the take-home message of the study is not that the lung function loss associated with exacerbations in those with severe COPD is unimportant. (esciencenews.com)

Background: Both sodium glucose cotransporter 2 inhibitors (SGLT-2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) have cardiovascular protective effects in patients with type 2 diabetes mellitus. (bvsalud.org)

CID was defined as any of the following: ≥100 mL decrease from baseline in pre-dose forced expiratory volume in 1 second (FEV 1 ), ≥4 point increase in St George's Respiratory Questionnaire score or a moderate-to-severe COPD exacerbation occurring after the first dose of study medication. (nature.com)
The investigators have strengthened the evidence base informing the use of venous blood gas analysis in the context of COPD exacerbations by performing a study specifically in this population, using peripherally sampled venous blood. (bmj.com)
The study at the meeting, called the BACE trial , was designed to test whether azithromycin could be employed in a more targeted approach to control exacerbations. (the-hospitalist.org)
This study aims to look at changes in inflammation and gene activity while surgery patients are on a heart-lung bypass machine. (nih.gov)
All patients who participated in the study either had experienced an acute exacerbation of COPD in the 12 months prior to study enrollment or had used supplemental oxygen at the time of enrollment. (science20.com)
Among those re-hospitalized, the study found that age, gender, inhaled medication regimens and respiration measurements were similar between patients treated with azithromycin and those who received placebo. (science20.com)
We study well characterized patient cohorts and we use various laboratory techniques, collaborating with laboratories both within Karolinska Institutet and other universities including international. (ki.se)
In one study of more than 1,000 patients admitted to several hospitals with an exacerbation of severe COPD, about 50% were admitted with a respiratory infec-tion, 25% with congestive cardiac failure, and 30% with no known cause for the exacerbation ( Connors 1996 ). (copdx.org.au)
A study of 173 patients with COPD reported an average of 1.3 (range 0 to 9.6) exacerbations annually. (copdx.org.au)
Contrary to the ECLIPSE study, Han reported that individual exacerbation rates vary significantly from year to year, and very few patients experience two or more exacerbations over successive years. (copdx.org.au)
By the end of the study, researchers discovered that 110 participants, 2.5% of the study sample, had moderate to severe forms of COPD. (news-line.com)
30 patients (14 AECOPD and 16 COPD) and 24 healthy controls were recruited for this study. (owlstonemedical.com)
Twenty seven patients with COPD‑AE were evaluated using a prospective longitudinal study design. (spandidos-publications.com)
The present study is part of a broader investigation with the purpose of investigating the repercussions of terminal conditions on the families of gravely ill patients hospitalized in Intensive Care Units (ICUs). (bvsalud.org)

The content within this essay is generalised across a patient group and does not relate to any specific patient, staff member or trust (NMC, 2018). (ukessays.com)

They explain how structured rehabilitation programs can make patients feel better and keep them out of hospitals. (bcmj.org)

In some cases, the distinction between chronic obstructive bronchitis and chronic asthmatic bronchitis is unclear and may be referred to as asthma COPD overlap (ACO). (msdmanuals.com)
In the 1980s, increasing experience with positive-pressure ventilation delivered through a mask in patients with obstructive sleep apnea led to this type of ventilatory support, initially in patients with neuromuscular respiratory failure. (medscape.com)
RÉSUMÉ La présente étude transversale a été conduite dans le but d'estimer la prévalence de la bronchopneumopathie chronique obstructive (BPCO) et d'identifier ses déterminants dans un échantillon de commodité de 325 fumeurs adultes à Bagdad (Iraq) en 2014. (who.int)

In COPD patients, AECOPD is often caused by infectious or bacterial pathogens and is frequently treated with a change in medication. (owlstonemedical.com)

However, some patients with this condition have neutrophilic inflammation, whereas, conversely, some patients without asthma have eosinophilic inflammation. (cmaj.ca)

In some regions, the widespread use of biomass fuels, such as wood, grasses, or other organic materials, also contributes to COPD prevalence. (msdmanuals.com)

COPD exacerbations contribute to a worsening of health-related quality of life over time [ 1 , 2 , 5 ] and their occurrence predicts the likelihood of dying [ 6 ]. (ersjournals.com)

Patients were randomized to receive either a daily dose of 250 mg of azithromycin or placebo for one year. (science20.com)
Sereflo should not be used for patients with mild asthma and may not be appropriate for patients with mild to moderate asthma, in whom a low dose of the inhaled corticosteroid, either alone or with a long-acting β 2 agonist, may be required. (medicines.org.uk)

This highlights that prevention of exacerbations in patients with COPD and concomitant CVD will improve both respiratory and CV health. (ersjournals.com)
The detection and prevention of RSV may be useful in the management of COPD. (spandidos-publications.com)

These findings support the early use of antibiotics in COPD patients who experience an acute exacerbation. (ices.on.ca)
Exacerbations as well as acute respiratory events in those participants without COPD were defined as requiring either antibiotics or systemic steroids. (esciencenews.com)

The patients experience dyspnoea, cough but have also significant co-morbidities and systemic manifestations. (ki.se)

Anatomy9

Organisms3

Diseases43

Chemicals and Drugs53

Analytical, Diagnostic and Therapeutic Techniques and Equipment67

Psychiatry and Psychology2

Phenomena and Processes16

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena5

Humanities1

Information Science3

Named Groups1

Health Care45

Geographicals3

Hospitalization24

Symptoms34

Mortality17

Clinical27

Severity9

Management of COPD exacerbations1

Hospitalisation8

Emphysema5

Annualised exacerbation rates1

Acute COPD exacerbations2

Pulmonary38

Outcomes4

Frequent7

Corticosteroids8

Occurred within 30 days1

Asthma exacerbations3

Diagnosis12

20231

20174

Comorbidities5

Sputum6

Admission5

Hospital admissions3

Airflow3

Treatment13

Among COPD patients1

Stable9

Assessment3

Severe acute1

Clinically defined1

Patient's3

Disease23

Moderate and severe1

Hospitalizations2

METHODS3

Risk16

Viral1

Infection6

People with COPD1

Cohort of patients2

Progression1

Lung function3

Cardiovascular1

Study14

20181

Rehabilitation1

Obstructive3

Bacterial1

Inflammation1

Prevalence1

Predicts1

Dose2

Prevention2

Antibiotics2

Cough1