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  • coronary heart d
  • A low ratio of serum eicosapentaenoic acid to arachidonic acid (EPA/AA) has been reported to correlate with coronary heart disease ( 1 - 3 ), and no previous studies have investigated serum polyunsaturated fatty acid (PUFA) levels exclusively in patients with diabetes, in whom atherosclerotic diseases are commonly found. (diabetesjournals.org)
  • We found that a lower serum EPA/AA ratio is associated with coronary heart disease and renal impairment in the older patients with diabetes. (diabetesjournals.org)
  • Therapy
  • HBO also has been used as an adjunct to antibiotics, debridement, and revascularization in the therapy of chronic, nonhealing wounds associated with diabetes or non-diabetic vascular insufficiency. (clinicaltrials.gov)
  • METHODS AND RESULTS: The Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome (MERLIN)-Thrombolysis in Myocardial Infarction (TIMI) 36 (MERLIN-TIMI 36) trial randomized 6560 patients hospitalized with a non-ST-elevation acute coronary syndrome to ranolazine or placebo in addition to standard therapy. (biomedsearch.com)
  • All of the patients had noninfectious uveitis that was resistant to other therapy, including corticosteroids and conventional immunomodulatory drugs. (aao.org)
  • Of the 88 patients, 72 (81.8 percent) achieved complete clinical remission while being treated with infliximab, and 33 patients (37.5 percent) were able to discontinue all other medications within 180 days of beginning infliximab therapy. (aao.org)
  • Thirty-two patients (36.4 percent) experienced at least one side effect, and 17 (19.3 percent) discontinued therapy as a result. (aao.org)
  • The Orthopaedic Section of the APTA recommends that clinicians should consider the use of laser therapy to decrease pain and stiffness in patients with Achilles tendinopathy. (chiromatrixbase.com)
  • In this study 320 diabetics were treated with PEMF, while 100 diabetics as a control group received only conservative therapy. (equimag.no)
  • In a supplementary randomised controlled trial, 537 non-overweight and overweight patients, mean age 59 years, who were already on maximum sulphonylurea therapy but had raised FPG (6.1-15.0 mmol/L) were allocated continuing sulphonylurea therapy alone (n=269) or addition of metformin (n=268). (nih.gov)
  • Epidemiological assessment of the possible association of death from diabetes-related causes with the concurrent therapy of diabetes in 4416 patients did not show an increased risk in diabetes-related death in patients treated with a combination of sulphonylurea and metformin (risk reduction 5% [-33 to p=0.78). (nih.gov)
  • Macroangiopathy
  • The book discusses the prevalence of macroangiopathy in asymptomatic diabetes, the prevalence of asymptomatic diabetes in human atherosclerosis, and the observations made in seeking evidence for macroangiopathy, microangiopathy, and neurological changes in patients with latent diabetes. (elsevier.com)
  • type
  • The serum levels of EPA and AA were determined in 744 Japanese patients with type 2 diabetes (aged 67 ± 12 years, 60% males, duration of diabetes 13 ± 11 years, estimated glomerular filtration rate [eGFR] 78 ± 32 mL/min/1.73 m 2 , serum EPA 79.6 ± 52.6 μg/mL, serum AA 189.5 ± 55.0 μg/mL) and in 285 age- and sex-matched subjects without diabetes between October and December 2012. (diabetesjournals.org)
  • We analyzed the medical records of 884 type 2 DM patients who were taking different antiplatelet agents for more than 2 years. (biomedsearch.com)
  • We studied type 1-, type 2 diabetic and non-diabetic subjects without a previous history of LEAD and a composite variable of ankle - plus toe blood pressures and indices was compared to ABI alone in detecting LEAD. (diva-portal.org)
  • Irbesartan Effects on Endothelial Dysfunction in Hypertensive Type II Diabetic Patients Comparing Atenolol. (springer.com)
  • Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes. (nih.gov)
  • Single voxel proton magnetic resonance spectroscopy ( 1 H-MRS) was performed at 1.5 T on right frontal, right parieto-temporal and right parieto-occipital white matter regions of the brain of 10 patients having type-2 diabetes along with 7 healthy controls. (beds.ac.uk)
  • A model to estimate the lifetime health outcomes of patients with type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS no. 68). (ox.ac.uk)
  • Maximal IMT was measured by high resolution ultrasound of the common carotid (CCA) and femoral arteries (FA) in 51 type 2 diabetics and 18 controls. (unboundmedicine.com)
  • insufficiency
  • in patients with peripheral arterial insufficiency improvement in all experimental measures, including the ability to walk without pain and blood flow to the legs. (healthy.net)
  • 80% success rate in patients with chronic cerebral insufficiency measured by symptoms such as vertigo, headache. (healthy.net)
  • 92% success rate in patients with cerebrovascular insufficiency and all pathological findings disappeared after 18 days of treatment. (healthy.net)
  • 40% success in elderly patients with arterial insufficiency of lower limbs. (healthy.net)
  • concentrations
  • Objective- In view of the possible link between serum sialic acid and cardiovascular disease in the general population, we investigated whether serum total and lipid-associated sialic concentrations are elevated in NIDDM patients compared with normal subjects. (diabetesjournals.org)
  • A larger study of circulating sialic acid concentrations as a risk factor for the development or marker of diabetic angiopathy is therefore justified. (diabetesjournals.org)
  • renal
  • As a medical student I also had an appointment at a dialysis unit, where patients with acute renal failure due to traffic accidents or preeclampsia would be dialyzed a few times to see, if the kidney would recover. (the-aps.org)
  • In addition to well-established risks among diabetic subjects for vascular diseases, renal disease, blindness, and amputations ( 1 , 2 ), diabetes also is associated with a poorer outcome from several acute medical conditions, including myocardial infarction ( 3 ), possibly stroke ( 4 ), and certain severe infections ( 5 ). (diabetesjournals.org)
  • outcomes
  • The presence of elevated pro-inflammatory cytokines and abnormalities in numerous systemic indicators of inflammation in diabetics makes it conceivable that diabetics mount an exaggerated immune response to C. neoformans (paradoxical to their defective immune state) leading to grave outcomes. (pubmedcentralcanada.ca)
  • Outcomes with the polymer-based paclitaxel-eluting TAXUS stent in patients with diabetes mellitus: the TAXUS-IV trial. (nih.gov)
  • CONCLUSIONS/INTERPRETATIONS: The UKPDS Outcomes Model is able to simulate event histories that closely match observed outcomes in the UKPDS and that can be extrapolated over patients' lifetimes. (ox.ac.uk)
  • Its validity in estimating outcomes in other groups of patients, however, remains to be evaluated. (ox.ac.uk)
  • CONCLUSIONS
  • CONCLUSIONS: Ranolazine, an inhibitor of late I(Na), appears to have antiarrhythmic effects as assessed by continuous ECG monitoring of patients in the first week after admission for acute coronary syndrome. (biomedsearch.com)
  • CONCLUSIONS - Among patients with peptic ulcer bleeding and perforation, diabetes appears to be associated with substantially increased short-term mortality. (diabetesjournals.org)
  • intervention
  • Earlier intervention with EPA might be desirable in younger diabetic patients with lower EPA/AA levels if the administration of EPA is effective for preventing vascular events. (diabetesjournals.org)
  • The DECIDE study will identify whether cardiovascular complication rates (the composite rate of myocardial infarction (MI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Grafting (CABG), stroke, carotid endarterectomy, peripheral revascularization, and peripheral amputation) are lower in patients who participate in managed diabetes care by ADEC in comparison to provincial and national rates. (clinicaltrials.gov)
  • Percutaneous coronary intervention in patients with diabetes is associated with high rates of restenosis and repeat revascularization due to excessive neointimal proliferation, a process that may be blunted with the site-specific delivery of paclitaxel. (nih.gov)
  • 0.31
  • The IMT of the FA, however, was not significantly different in the two groups (patients: 0.80 + 0.30 mm, controls: 0.75 +/- 0.31 mm). (unboundmedicine.com)
  • markedly
  • I build a plethysmograph and observed that the spontaneous variability in the resting blood flow was markedly reduced in some diabetic patients despite a normal blood flow. (the-aps.org)
  • The patients' body-weight was markedly greater and blood pressure significantly higher than that of the controls. (unboundmedicine.com)
  • acute
  • Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the Metabolic Efficiency With Ranolazine for Less Ischemia in Non ST-Elevation Acute Coronary Syndrome Thrombolysis in Myocardial Infarction 36 (MERLIN-TIMI 36) randomized controlled trial. (biomedsearch.com)
  • Ankle
  • The measurement of ankle-to- brachial blood pressure index (ABI) to screen for asymptomatic LEAD in diabetic subjects is unreliable since a large proportion of patients have stiff ankle arteries (mediasclerosis) and thus may display a too high ABI. (diva-portal.org)
  • Thus, it was found that toe blood pressure measurements, alone or in combination with ankle blood pressure measurements, increase the sensitivity for finding early asymptomatic LEAD in diabetic subjects. (diva-portal.org)
  • diabetes related
  • Early addition of metformin in sulphonylurea-treated patients was associated with an increased risk of diabetes-related death (96% increased risk [95% CI 2- p=0.039) compared with continued sulphonylurea alone. (nih.gov)
  • A combined analysis of the main and supplementary studies showed fewer metformin-allocated patients having diabetes-related endpoints (risk reduction 19% [2- p=0.033). (nih.gov)