• Cerebral vasospasm leading to delayed cerebral ischemia (DCI) continues to be a major complication and source of morbidity in cases of aSAH. (medscape.com)
  • For this reason, routine surveillance imaging studies are carried out to supplement the neurologic examination with the aim of diagnosing vasospasm before the onset of delayed cerebral ischemia (DCI). (medscape.com)
  • A logistic regression model was constructed to evaluate the association of the CONUT score with a modified Rankin scale (mRS) ≥ 3 and delayed cerebral ischemia (DCI). (nature.com)
  • 1] Manan Shah, Lee Birnbaum, Jennifer Rasmussen, Padmini Sekar, Effect of Hyperosmolar Therapy on Outcome following Spontaneous Intracerebral Hemorrhage: ERICH Study, J Stroke Cerebrovasc Dis. (clausiuspress.com)
  • 2] Co K A, Navarro J. Assessing clinical outcome using brain score as a predictor of hematoma growth in acute spontaneous intracerebral hemorrhage (ICH) patients in a tertiary hospital in Manila. (clausiuspress.com)
  • Transcranial Doppler combined with quantitative EEG brain function monitoring and outcome prediction in patients with severe acute intracerebral hemorrhage. (clausiuspress.com)
  • The high incidence of intracerebral hemorrhage illustrates the clinical differences from other hereditary cerebral small-vessel diseases, such as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL), and hereditary endotheliopathy, retinopathy, nephropathy, and stroke (HERNS) 3 . (nature.com)
  • In our patient, neuroimaging revealed a multifocal distribution of haemorrhages in the intracerebral, subarachnoid, and subdural compartments. (bmj.com)
  • In the published literature cortical subarachnoid haemorrhage is the most frequent haemorrhagic manifestation of this condition, followed by intracerebral haemorrhage. (bmj.com)
  • Cerebellar hemorrhages (CHs) result from the same causes as other intracerebral hemorrhages. (medscape.com)
  • An estimated 10% of intracerebral hemorrhages are believed to be cerebellar in location. (medscape.com)
  • Up to 30-45% of strokes are intracerebral hemorrhages in some Chinese and Japanese series. (medscape.com)
  • OBJECTIVE: Spontaneous intracerebral hemorrhage (ICH) and ischemic stroke share common vascular risk factors such as aging and hypertension. (koreamed.org)
  • Intracerebral hemorrhage (ICH) and extension of parenchymal bleeding into the ventricles (ie, intraventricular hemorrhage [IVH]) are detailed here. (medscape.com)
  • Intracerebral hemorrhage accounts for 8-13% of all strokes and results from a wide spectrum of disorders. (medscape.com)
  • Intracerebral hemorrhage is more likely to result in death or major disability than ischemic stroke or subarachnoid hemorrhage. (medscape.com)
  • Intracerebral hemorrhage and accompanying edema may disrupt or compress adjacent brain tissue, leading to neurological dysfunction. (medscape.com)
  • Nonpenetrating and penetrating cranial trauma are also common causes of intracerebral hemorrhage.Patients who experience blunt head trauma and subsequently receive warfarin or clopidogrel are considered at increased risk for traumatic intracranial hemorrhage. (medscape.com)
  • Intraventricular hemorrhage occurs in one third of intracerebral hemorrhage cases from extension of thalamic ganglionic bleeding into the ventricular space. (medscape.com)
  • Each year, intracerebral hemorrhage affects approximately 12-15 per 100,000 individuals, including 350 hypertensive hemorrhages per 100,000 elderly individuals. (medscape.com)
  • The overall incidence of intracerebral hemorrhage has declined since the 1950s. (medscape.com)
  • Asian countries have a higher incidence of intracerebral hemorrhage than other regions of the world. (medscape.com)
  • Annually, more than 20,000 individuals in the United States die of intracerebral hemorrhage. (medscape.com)
  • Pontine or other brainstem intracerebral hemorrhage has a mortality rate of 75% at 24 hours. (medscape.com)
  • Intracerebral hemorrhage has a higher incidence among populations with a higher frequency of hypertension, including African Americans. (medscape.com)
  • A higher incidence of intracerebral hemorrhage has been noted in Chinese, Japanese, and other Asian populations, possibly due to environmental factors (eg, a diet rich in fish oils) and/or genetic factors. (medscape.com)
  • Intracerebral hemorrhage has a slight male predominance, though study results have been conflicting. (medscape.com)
  • Phenylpropanolamine use has been associated with intracerebral hemorrhage in young women. (medscape.com)
  • Incidence of intracerebral hemorrhage increases in individuals older than 55 years and doubles with each decade until age 80 years. (medscape.com)
  • One patient had a post-operative TIA, none had post-operative intracerebral or surgical site haemorrhage. (lu.se)
  • Ischemic Stroke Ischemic stroke is sudden neurologic deficits that result from focal cerebral ischemia associated with permanent brain infarction (eg, positive results on diffusion-weighted MRI). (msdmanuals.com)
  • The purpose of the present study was to investigate the association of oral anticoagulant (OAC) use and the development of new CMBs in cardioembolic stroke patients with atrial fibrillation. (nih.gov)
  • We prospectively followed cardioembolic stroke patients with atrial fibrillation who had been hospitalized in the stroke center of our hospital, had been prescribed anticoagulants at discharge, and underwent repeated brain MRI with an interval of at least one year from the baseline MRI. (nih.gov)
  • Our findings suggest that DOAC compared with WF use at discharge is associated with a lower incidence of new CMBs in cardioembolic stroke patients with atrial fibrillation. (nih.gov)
  • Spontaneous subarachnoid hemorrhage (SAH) affects individuals with a mean age of 55 years and accounts for 5% of stroke cases. (nature.com)
  • Rupture of cerebral aneurysm (subarachnoid hemorrhage) can cause stroke. (awm-math.org)
  • Newswise - Bleeding in and around the brain (cerebral hemorrhage, including intra-cerebral hemorrhage, subdural hematoma, subarachnoid hemorrhage among other forms), from whatever cause (stroke, ruptured aneurysm, stroke, tumor, trauma, etc) can be very irritating to the electrical cells of the brain and affect how these cells transmit signals. (newswise.com)
  • About 20%-30% of stroke patients will experience dysarthria, and most of them will have psychological obstacles [ 3 ]. (hindawi.com)
  • To examine the therapeutic effect of intravenous recombinant tissue plasminogen activator (rt-PA) therapy for stroke patients receiving maintenance hemodialysis (HD). (karger.com)
  • Of 600 stroke patients receiving intravenous rt-PA using 0.6 mg/kg alteplase who were enrolled in a multicenter observational study in Japan, 4 patients (3 men, 64-77 years old) on maintenance HD were studied. (karger.com)
  • People with hereditary cerebral amyloid angiopathy often have progressive loss of intellectual function (dementia), stroke, and other neurological problems starting in mid-adulthood. (medlineplus.gov)
  • The first sign of the Icelandic type of hereditary cerebral amyloid angiopathy is typically a stroke followed by dementia. (medlineplus.gov)
  • The aim of this study was to evaluate the outcome in patients treated with carotid endarterectomy (CEA) after EVT, comparing complication rates among patients undergoing CEA for stroke without previous EVT. (lu.se)
  • Methods: This was a registry study of all patients (n = 3 780) treated with CEA after stroke in Sweden and the capital Helsinki region, Finland, from January 2011 to September 2020. (lu.se)
  • The stroke and death rate in patients treated with CEA only was 3.7% (95% CI 3.2 - 4.4), CEA was performed a median of eight days after QNE, and in 79.7% in ≤14 days. (lu.se)
  • Results were comparable with those undergoing CEA only, despite the EVT+CEA patients having more severe stroke symptoms prior to surgery, and timing was similar. (lu.se)
  • Forty-five patients who had undergone the surgery for chronic subdural hematoma were included in this study. (go.jp)
  • The purpose of this study was to clarify the criteria for initial treatment of chronic subdural hematoma (CSDH) by com-paring the backgrounds and post-treatment courses of patients who underwent drainage or middle meningeal artery (MMA) emboliza-tion for CSDH. (go.jp)
  • Hemorrhage within the meninges or the associated potential spaces, including epidural hematoma, subdural hematoma, and subarachnoid hemorrhage, is covered in detail in other articles. (medscape.com)
  • Critical Care Alert: Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage A 57-year-old male with a history of hypertension and diabetes develops a severe headache and nausea. (emra.org)
  • citation needed] Complications of severe acute hypertension can include seizures, pulmonary edema, myocardial infarction, or cerebral hemorrhage. (wikipedia.org)
  • Neurologic end-organ damage due to hypertensive emergencies includes cerebral infarction, subarachnoid haemorrhage and others. (clickpress.com)
  • Patients with acute myocardial infarction need to be treated with intravenous esmolol. (clickpress.com)
  • In this study, we have compared baseline clinical characteristics, angiographic findings and subsequent outcomes in patients with LBBB versus ST-elevation myocardial infarction (STEMI) referred to our tertiary centre for primary percutaneous coronary intervention (PCI). (bvsalud.org)
  • We report a rare case of acute myocardial infarction secondary to coronary embolisation of valvular vegetation in a patient with infective endocarditis, and we highlight how the management of this phenomenon may not be the same. (bvsalud.org)
  • However, the etiology of cerebral vasospasm remains poorly understood. (medscape.com)
  • There are many postulated theories as to the etiology of cerebral vasospasm after aSAH, but the mechanisms ultimately responsible for vasospasm are still incompletely understood. (medscape.com)
  • More invasive means of treating vasospasm depend on the utilization of cerebral angiography and include intra-arterial vasodilator administration and balloon angioplasty. (medscape.com)
  • Cerebral angiography revealed an anterior communicating artery aneurysm. (medscape.com)
  • Angiography demonstrated severe narrowing of the right anterior cerebral artery (ACA). (medscape.com)
  • Advances in neuroimaging have led to revision of treatment concepts for cerebellar hemorrhage (CH). In the pre-computed tomography (CT) era, patients with large hematomas (which were detected by angiography or at postmortem examination) were overrepresented in clinical series. (medscape.com)
  • Conclusion Cerebral angiography in adults, children and infants is a safe procedure with low risk of permanent neurological complications. (thieme-connect.de)
  • 8. Sung W, Arnaldo B, Sergio C, Juliana S, Michel F. Terson's syndrome as a prognostic factor for mortality of spontaneous subarachnoid haemorrhage. (cns.org)
  • within the last decades several clinical trials were performed to analyze the effectiveness of cisternal and ventricular lavage on cerebral vasospasm in patients suffering from subarachnoid hemorrhage. (nih.gov)
  • so far the literature search revealed a total of nine clinical trials using cisternal or ventricular lavage alone in patients suffering from subarachnoid hemorrhage. (nih.gov)
  • It is less sensitive in some patients with unfavorable bony anatomy "windows" that hinder soft-tissue evaluation, and it is subject to user error or variability, which inevitably affects its clinical applicability. (medscape.com)
  • Objective: To explore the clinical application effect of predictive nursing procedure on the patients with cerebral hemorrhage. (clausiuspress.com)
  • The clinical presentation was consistent with reversible cerebral vasoconstriction syndrome The resolution of the angiographic abnormalities on a follow-up study after an interval of 8 weeks, supported this diagnosis. (bmj.com)
  • Location of the hemorrhage (midline vs hemispheric) is important in determining symptoms and clinical course. (medscape.com)
  • In this study, we examined the association of clinical outcome with the Controlling Nutritional Status (CONUT) score during hospitalization in aSAH patients. (nature.com)
  • Here, we retrospectively analyzed the relationship between clinical outcomes and the CONUT score in aSAH patients during hospitalization. (nature.com)
  • These five patients had subarachnoid hemorrhage and were similar in age and clinical presentation. (ajnr.org)
  • A study reported today at the 64th American Epilepsy Society Annual Meeting has found that, of patients with a cerebral hemorrhage or hematoma, one in four had a diagnosis of sub-clinical seizures while in the ICU: sub-clinical seizures can only be detected with continuous electroencephalographic (EEG) recording. (newswise.com)
  • Lead investigator Jeffrey M. Politsky, M.D., and colleagues report that, "The fact that 700 patients with cerebral hemorrhage did not undergo EEG evaluation suggests that the diagnosis of sub-clinical seizures was missed in over 200 cases. (newswise.com)
  • Missing a diagnosis of sub-clinical seizures might well have a negative impact on patient outcome. (newswise.com)
  • Reported prognostic factors for poor short-term outcome in CVST include anatomical characteristics of disease such as the presence of brain herniation and hemorrhage, or features of the clinical presentation such as seizures, depressed consciousness, and altered mental status. (cdc.gov)
  • As a leader in lung cancer research, we continue to try to advance science for our patients by building upon the standard we set several years ago with KEYTRUDA," said Dr. Gregory Lubiniecki, Vice President, Global Clinical Development, Merck Research Laboratories. (streetinsider.com)
  • After bringing the first FDA-approved RET inhibitor to patients earlier this year, we are pleased to follow up with detailed safety and efficacy findings from the largest clinical trial in patients with RET -driven cancers," said Anne White , president of Lilly Oncology. (prnewswire.com)
  • Given that patients living with RET fusion-positive NSCLC face a high lifetime risk of disease progression to the brain, intracranial effectiveness is a significant consideration in the treatment journey," added Vivek Subbiah , M.D., associate professor of Investigational Cancer Therapeutics and medical director of the Clinical Center for Targeted Therapy at The University of Texas MD Anderson Cancer Center and co-investigator for LIBRETTO-001. (prnewswire.com)
  • The knowledge of the pathophysiology of DCI has evolved over years and it is thought that a combination of multiple mechanisms underlies DCI and poor functional outcomes, including cerebral vascular dysregulation, microthrombosis, cortical spreading depolarization, and neuroinflammation [ 1 ]. (biomedcentral.com)
  • On the Fisher Scale, the thickness of the aSAH clot and the presence of intraventricular hemorrhage (IVH) are strong predictors of vasospasm. (medscape.com)
  • Isolated intraventricular hemorrhage frequently arise from subependymal structures including the germinal matrix, AVMs, and cavernous angiomas. (medscape.com)
  • Hallevi et al reviewed the charts and CT scans of patients with intraventricular hemorrhage (IVH) to determine if the extension of the hemorrhage could be measured. (medscape.com)
  • 5] Andrew M. Naidech, Intracranial Hemorrhage,Am J Respir Crit Care Med. (clausiuspress.com)
  • Intracranial hemorrhage (ie, the pathological accumulation of blood within the cranial vault) may occur within brain parenchyma or the surrounding meningeal spaces. (medscape.com)
  • According to one study, patients receiving clopidogrel have a significantly higher prevalence of immediate traumatic intracranial hemorrhage compared with patients receiving warfarin. (medscape.com)
  • Delayed traumatic intracranial hemorrhage is rare and occurred only in patients receiving warfarin. (medscape.com)
  • Guidelines have recommended these modalities as reasonable for treatment of symptomatic patients who are not responding to hypertensive therapy. (medscape.com)
  • Long-standing hypertension with degenerative changes in the vessel walls and subsequent rupture is believed to be the most common cause of a typical CH. Approximately two thirds of CHs are believed to be hypertensive hemorrhages. (medscape.com)
  • Risk factors for hypertensive crisis: importance of out-patient blood pressure control. (bmj.com)
  • Intermittent claudication and severe renal artery stenosis are independently associated in hypertensive patients referred for renal arteriography. (bmj.com)
  • Angiogram shows severe narrowing of right anterior cerebral artery. (medscape.com)
  • When used at high doses in doseranging studies in patients with acute leukemia , FLUDARA (fludarabine) FOR INJECTION was associated with severe neurologic effects, including blindness, coma, and death. (rxlist.com)
  • This severe central nervous system toxicity occurred in 36% of patients treated with doses approximately four times greater (96 mg/m²/day for 5-7 days) than the recommended dose. (rxlist.com)
  • Similar severe central nervous system toxicity, including coma, seizures, agitation and confusion, has been reported in patients treated at doses in the range of the dose recommended for chronic lymphocytic leukemia. (rxlist.com)
  • Three hours after treatment, the patient became comatose and had severe systemic hypotension attributable to heart failure. (ajnr.org)
  • Whilst waiting for surgery, our patient developed severe central crushing chest pain with associated anterior ST segment elevation on his electrocardiogram. (bvsalud.org)
  • Cerebral aneurysms are particularly dangerous because of their difficulty to treat and their high mortality and morbidity rate. (awm-math.org)
  • Time course of cerebrovascular reactivity in patients treated for unruptured intracranial aneurysms: A one-year transcranial Doppler and acetazolamide follow-up study. (uib.no)
  • Differences in anatomical distribution, gender, and sidedness between ruptured and unruptured intracranial aneurysms in a defined patient population. (uib.no)
  • Subarachnoid hemorrhages (SAH) due to true aneurysms of the Posterior Cerebral Artery (PCA) during puerperium in young and healthy females are extremely rare. (uni-regensburg.de)
  • We will cover 10 years of experience in this area and divide our observations in 3 parts: cerebral angiograms (part I), carotid angioplasties (part II) and intracranial aneurysms (part III). (thieme-connect.de)
  • Brain Aneurysms Brain aneurysms are focal dilations in the cerebral arteries. (msdmanuals.com)
  • nimodipine is currently recommended as first-line medical treatment for preventing post-aSAH cerebral vasospasm. (medscape.com)
  • [ 5 ] has been found to be elevated in cerebrospinal fluid (CSF) after aSAH and may play a role in cerebral vasospasm and DCI. (medscape.com)
  • Cerebral vasospasm has been estimated to occur in 12-30% of the approximately 30,000 North American patients who experience aSAH each year. (medscape.com)
  • [ 7 , 8 ] It has been estimated that close to 50% of patients suffering from aSAH die before reaching medical care. (medscape.com)
  • There are certain patient characteristics that may increase the likelihood of vasospasm occurring in a patient with aSAH. (medscape.com)
  • Patients transported to the emergency room for aSAH and diagnosed with World Federation of Neurosurgical Societies (WFNS) grade III and IV aSAH between April 2004 and March 2021 were enrolled. (nature.com)
  • 127 patients diagnosed with WFNS grade III and IV aSAH were analyzed. (nature.com)
  • These findings indicate that CONUT score during hospitalization may be a useful daily marker for predicting poor outcomes in aSAH patients. (nature.com)
  • The social and economic losses of patients with aSAH in the event of death or inability to return to society are therefore substantial 3 . (nature.com)
  • 4 at admission independently predicted patients' functional outcome status at 3 months after aSAH 7 . (nature.com)
  • However, it is unclear whether the CONUT score during hospitalization influences the functional outcomes of aSAH patients. (nature.com)
  • Our goal was to evaluate the feasibility and potential role of bedside optical coherence tomography (OCT) in Terson's Syndrome (TS) in patients with acute subarachnoid hemorrhage (aSAH) and its potential role in blindness prevention. (cns.org)
  • Open label pilot study: 31 patients with angiographic diagnosis of aSAH were first screened for TS with dilated fundoscopy and then with OCT in the acute phase and at 6-week follow-up visits. (cns.org)
  • OCT identified 7 patients (22.6% incidence of TS in our aSAH sample: 7 in the acute phase, a large retinal detachment was initially missed by fundoscopy and diagnosed by OCT in follow up clinic). (cns.org)
  • CT perfusion studies have been shown to be more useful for diagnosing vasospasm in patients with delayed neurologic deficits than they are in asymptomatic patients. (medscape.com)
  • A metaanalysis, investigating a total of 652 included patients revealed a significant reduction of delayed neurological deficits, a significant increase of outcome and a significant decrease of mortality in the treatment group. (nih.gov)
  • The 30-day and 6-month mortality rate is 39% and 49%, respectively, and only 23% of patients have a favorable outcome, as evaluated using a modified Rankin scale (mRS) score of 0-2 2 . (nature.com)
  • Mortality Prediction in Cerebral Hemorrhage Patients Using Machine Learning Algorithms in Intensive Care Units. (cdc.gov)
  • To investigate the role of DNA methylation in DCI risk, we conducted an epigenome-wide association study (EWAS) in 68 patients followed up to 1 year after the initial aneurysm rupture. (biomedcentral.com)
  • Thrombolysis risks intra-cerebral hemorrhage from mycotic aneurysm rupture. (bvsalud.org)
  • Disequilibrium in patients with posterior fossa arachnoid cysts. (uib.no)
  • Can ultrasound predict nerve injury following posterior tibial nerve block in diabetic patients with peripheral neuropathy? (asra.com)
  • Hemorrhage, cerebellar herniation, and cerebral venous thrombosis in a patient with naegleria fowleri: A rare presentation. (acquaintpublications.com)
  • Appearances were likely secondary to extremely sluggish flow/vasculitis phenomenon likely cerebral venous thrombosis (CVT) along with marked cerebellar tonsillar herniation. (acquaintpublications.com)
  • Three-dimensional reconstruction of cerebral angiogram showing anterior communicating artery aneurysm. (medscape.com)
  • Anterior segment examination showed subconjunctival hemorrhage in both eyes with normal pupil size pupil that reacted to light. (thepajo.org)
  • The phenotypic spectrum of COL4A1 -related disorders has been expanding, and accumulating data have shown that extracerebral hemorrhages may also occur 4 . (nature.com)
  • Cerebral aneurysm can occur anywhere in the brain, but most are located along a loop of arteries that run between the underside of the brain and the base of the skull (Circle of Willis). (awm-math.org)
  • How often do chronic extra-cerebral haematomas occur in patients with intracranial arachnoid cysts? (uib.no)
  • Aneurysmal hemorrhage may occur at any age but is most common from age 40 to 65. (msdmanuals.com)
  • In a study that compared three-dimensional (3D) spin-echo-based black-blood MRA (BBMRA) with time-of-flight (TOF)-MRA for detection of cerebral vasospasm in the early posttreament period after subarachnoid hemorrhage, Takano et al found that BBMRA, owing to its contrast properties, may be superior to TOF-MRA for the evaluation of intracranial arteries. (medscape.com)
  • Subarachnoid haemorrhage: what happens to the cerebral arteries? (medscape.com)
  • b Other category includes six patients with recent neurosurgery, three with toxic levels of anticonvulsant medications, three with reactions to non-anticonvulsant medication, three with systemic lupus erythematosus, and several other less frequently occurring causes. (cdc.gov)
  • Cerebral microbleeds (CMBs) are a magnetic resonance imaging (MRI) marker for cerebral small vessel disease. (nih.gov)
  • Mutated COL4A1 disrupts the basic structure of cerebral small vessels via a dominant-negative effect or haploinsufficiency, which results in autosomal-dominant cerebral small-vessel disease 1 , 2 . (nature.com)
  • Here, we report a Japanese family with hereditary cerebral small-vessel disease with a novel missense variant in COL4A1 , including a patient who presented with recurrent epistaxis and glioblastoma. (nature.com)
  • Conclusion: The application of predictive nursing procedure for cerebral hemorrhage patients can accelerate patients' recovery, promote service quality, improve patients' life quality and prevent relevant complications, so it deserves to be promoted and applied. (clausiuspress.com)
  • This case report warrants the importance of ocular screening in a patient having systemic complications of DF. (thepajo.org)
  • Herein, we report a case of bilateral retinal hemorrhages with macular edema in a patient with neurological complications due to DF. (thepajo.org)
  • reported in a prospective study of 58 SAH patients that a negative energy balance during the first 7 days after SAH correlated with the number of infectious complications 10 . (nature.com)
  • These researchers also showed in a prospective observational study of 229 SAH patients that a negative nitrogen balance during the first 14 post-bleed days is a risk factor for infectious complications and is associated with poor outcomes (mRS ≥ 4) at 3 months 11 . (nature.com)
  • The goal of part I is to statistically assess the cerebral angiograms, their indications, risks and complications, as well as to do a technical review. (thieme-connect.de)
  • Are Seizures Due to Cerebral Hemorrhage Going Undiagnosed in the ICU? (newswise.com)
  • Seizures were detected in 25% of patients who had been evaluated, with no significant difference in seizure activity found among the different types of intra-cranial hemorrhage. (newswise.com)
  • A more detailed analysis of the relationship of seizures in the acute setting of cerebral hemorrhage and patient outcome is needed. (newswise.com)
  • We performed a retrospective investigation of 23 and 21 patients who underwent drainage and MMA embolization, respec-tive-ly, performed between April 2020 and July 2022 as initial treatment for unilateral CSDH. (go.jp)
  • One case of wire-induced distal vessel injury was trapped with detachable coils without further neurological detriment of the patient. (bmj.com)
  • Results A total of 4,084 procedures performed, 21,811 vessels studied, average vase 7.62/2.82 vessel and patient/procedure. (thieme-connect.de)
  • METHODS: Twenty-three patients (mean age, 60.6 ± 8.1 years) with CCS and single-vessel coronary stenosis underwent cardiac catheterization. (bvsalud.org)
  • OBJECTIVES: Adenosine hyperemia is an integral component of the physiological assessment of obstructive coronary artery disease in patients with chronic coronary syndrome (CCS). (bvsalud.org)
  • Continuous cervical epidural block is an excellent treatment for intractable hiccups and is effective in preventing recurrence in patients that do not respond to conventional therapies," Dr. Sang Sik Choi and colleagues from Korea University Guro Hospital, in Seoul, write in the February issue of Medicine. (medscape.com)
  • The biggest limitation of the study is that while the patients were receiving a bolus/continuous epidural infusion, they were also undergoing other treatments (not defined) designed at addressing the causative factors for the hiccups," noted Dr. Christiansen, who was not involved in the study. (medscape.com)
  • Thus, it is impossible to say if the epidural infusion was beneficial or if the patient improved because the causative factor(s) of the hiccup was treated. (medscape.com)
  • If the study would be repeated, I would suggest that the researcher consider randomizing the patients into two groups: group 1 gets the epidural bolus/infusion while group 2 gets treatment for their causative factors. (medscape.com)
  • Admission imaging also demonstrated subarachnoid blood in over the right superior cerebral convexities. (bmj.com)
  • There are several risk factors for cerebral aneurysm, among which are hypertension, heavy alcoholic consumption and cigarette smoking. (awm-math.org)
  • Characteristics of patients with uncontrolled hypertension in the United States [published correction appears in N Engl J Med. (bmj.com)
  • KEYTRUDA is approved for the treatment of adult and pediatric patients with unresectable or metastatic MSI-H or dMMR solid tumors that have progressed following prior treatment and who have no satisfactory alternative treatment options. (businesswire.com)
  • KEYNOTE-158 (ClinicalTrials.gov, NCT02628067 ) is an ongoing global, open-label, non-randomized, multi-cohort, multi-center, Phase 2 study evaluating KEYTRUDA in patients with multiple types of advanced solid tumors - including endometrial carcinoma - that have progressed on standard of care therapy. (businesswire.com)
  • The study enrolled both treatment-naive patients and heavily pretreated patients with a variety of advanced solid tumors including RET fusion-positive NSCLC, RET -mutant MTC, RET fusion-positive thyroid cancer, and certain other advanced solid tumors with RET alterations. (prnewswire.com)
  • Up to 50 percent of patients with RET fusion-positive NSCLCs can have tumors that metastasize to the brain. (prnewswire.com)
  • Five days after presentation, the patient became symptomatic as a consequence of cerebral vasospasm. (medscape.com)
  • Cerebral angiogram obtained on posthemorrhage day 5 in patient symptomatic from vasospasm. (medscape.com)
  • Introduction/Purpose To report our long-term results of mechanical angioplasty using stentrievers for recurred symptomatic cerebral vasospasm in subarachnoid hemorrhage patients. (bmj.com)
  • Conclusion Mechanical angioplasty using stent-retrievers for the delayed symptomatic vasospasm in the subarachnoid hemorrhage patients can be a feasible option especially for the recurred cases after chemical only angioplasty. (bmj.com)
  • The hemorrhage is remote from the surgical site or anatomic defect and may result from transient occlusion or rupture of superior cerebellar bridging veins. (medscape.com)
  • In making such predictions, only patients with a risk of aneurysmal rupture will thus be exposed to the risk of surgery. (awm-math.org)
  • Al- developed during hospitalization for non- though reliable statistics on the prevalence renal-related problems in patients whose of ARF among different tropical countries serum creatinine level on admission was are not available, statistics based on refer- normal. (who.int)
  • [ 4 ] The alteration of these regulatory processes results in excess cerebral arterial vasoconstriction. (medscape.com)
  • Our patient presented with recurrent thunderclap headache, a characteristic presentation of the reversible cerebral vasoconstriction syndrome. (bmj.com)
  • Subdural haemorrhage is a less well reported manifestation occurring in just 2% of patients in the largest case series of reversible cerebral vasoconstriction to date. (bmj.com)
  • An awareness of the multiple haemorrhagic presentations of reversible cerebral vasoconstriction syndrome may aid in earlier recognition of this syndrome. (bmj.com)
  • In conclusion, there is strong evidence that cisternal or ventricular lavage alone and in combination with kinetic therapy lead to a reduction of cerebral vasospasm and better outcome in patients suffering from subarachnoid hemorrhage. (nih.gov)
  • With the availability of cranial CT, patients with milder symptoms and smaller hematomas are increasingly detected. (medscape.com)
  • The main symptoms of dysarthria patients include unclear speech, long tone, dysrhythmic control of speech speed, monotonous language, and silence. (hindawi.com)
  • Measures included PROMIS-Fatigue SFs (7a, 8a, 4a), other PROMIS measures of RA symptoms, and selected patient reported outcomes including RAND-36 Vitality, Fatigue NRS, and patient global assessment of disease activity. (springer.com)
  • While these results are not what we hoped for, we are proud of the foundational role that KEYTRUDA has established in the treatment of certain types of lung cancer, and we are committed to continuing to research how we can further improve responses to our medicines for patients with difficult-to-treat forms of the disease. (streetinsider.com)
  • NEJM published separate articles focusing on efficacy and safety data in the RET fusion-positive NSCLC and RET -altered thyroid patient cohorts independently, with data demonstrating durable objective responses across both patient populations. (prnewswire.com)
  • The clinically meaningful responses observed in this study demonstrate that selpercatinib can help fill this need, offering a valuable treatment option to these patients. (prnewswire.com)
  • 3 Among previously treated NSCLC patients with measurable brain metastases, 10 out of 11 patients observed intracranial responses (CNS ORR), with all patients experiencing a CNS DoR of greater than or equal to six months. (prnewswire.com)
  • CONCLUSIONS: In patients with CCS and coronary stenosis, invasive hemodynamic responses differed markedly between IV adenosine hyperemia versus physical exercise stress. (bvsalud.org)
  • AD occurs most often in individuals with spinal cord injuries with lesions at or above the T6 spinal cord level, although it has been reported in patients with lesions as low as T10. (wikipedia.org)
  • Materials and Methods We retrospectively reviewed medical records and radiological images of 7 patients who developed delayed vasospasm following subarachnoid hemorrhage and showed recurrence after initial angioplasty using intra-arterial vasodilator infusion from 2014 to 2017 at our institution. (bmj.com)
  • Neurological improvements were noted in 6 (86%) patients after the procedures which include subsequent intra-arterial vasodilator infusion. (bmj.com)
  • Methods: We enrolled 23 patients with neck and. (koreamed.org)
  • METHODS AND RESULTS: A large retrospective observational study was performed involving 1875 consecutive patients presenting to our single tertiary cardiac centre for primary PCI over a 27-month period. (bvsalud.org)
  • Patients and methods. (bvsalud.org)
  • Of those patients who are able to reach neurosurgical centers and have their aneurysm treated, an estimated 14% either die or sustain significant morbidity as a result of cerebral vasospasm. (medscape.com)
  • Adult RA patients were recruited from an online arthritis patient community and an observational cohort drawing from three academic medical centers. (springer.com)
  • The investigators reviewed the records of more than 950 cerebral hemorrhage and hematoma patients consecutively admitted to the intensive care unit during a period of more than three years. (newswise.com)
  • The publication highlights the first 105 consecutively enrolled RET fusion-positive metastatic NSCLC patients treated with at least prior platinum-based chemotherapy as well as 39 systemic treatment naïve patients. (prnewswire.com)