• Extrahepatic neuroendocrine tumors were completely ruled out by performing gastrointestinal endoscopy, computed tomography (CT) on the chest and abdomen, and whole-body positron emission tomography-computed tomography (PET-CT). (medscape.com)
  • my fathers neuroendocrine tumors in his liver? (cancer.org)
  • Patients with type 3 tumors have normal levels of gastrin and stomach acid. (cancer.org)
  • Neuroendocrine tumors (NETs) consist of a diverse family of tumors which are derived from the neuroendocrine system. (nih.gov)
  • Everolimus tablets are indicated for the treatment of adult patients with progressive neuroendocrine tumors of pancreatic origin (PNET) with unresectable, locally advanced or metastatic disease. (nih.gov)
  • The NCI Surgery Branch has developed an experimental therapy that involves taking white blood cells from patients' tumors, growing them in the laboratory in large numbers, and then giving the cells back to the patient. (nih.gov)
  • Follow up: Patients will return to the clinic for a physical exam, review of side effects, lab tests, and scans about every 1-3 months for the first year, and then every 6 months to 1 year as long as their tumors are shrinking. (nih.gov)
  • Note: neuroendocrine tumors are not eligible. (nih.gov)
  • And based on the results of the LITESPARK-001 trial, belzutifan got FDA approval for patients with VHL associated tumors, which were not there, which are not ready for surgery. (urotoday.com)
  • Go to the Neuroendocrine Tumors (NETs) Support Group. (mayoclinic.org)
  • Li-Fraumeni syndrome is a cancer predisposition syndrome caused by germline TP53 tumor suppressor gene mutations, with no previous association with pancreatic neuroendocrine tumors (PNETs). (biomedcentral.com)
  • Our series of 77 sporadic duodenal neuroendocrine tumors (NETs) includes 18 patients (23.4%) with gastrinomas and ZES. (kb.se)
  • We recharacterized 168 colon carcinomas and compared pT2 int cases to bona fide pT2 and pT3 tumors. (allenpress.com)
  • These data support the conclusion that pT2 int carcinomas have clinicopathologic characteristics and are associated with patient outcomes more closely aligned with pT2 rather than pT3 tumors. (allenpress.com)
  • Pancreatic neuroendocrine tumors (pNETs) are rare neoplasms arising from the pancreatic islet of Langerhans and can be functioning or non-functioning based on the clinical symptoms caused by hormonal secretions. (nih.gov)
  • Although much progress has been made in the past 2-3 years in terms of understanding signaling pathways in gastroenteropancreatic neuroendocrine tumors (GEP-NENs), approved treatment options are still limited. (enets.org)
  • Urothelial carcinoma represents 90% of all bladder tumors, while SCBC is found in only 0.5% to 1.2% of patients. (medpagetoday.com)
  • Application of artificial intelligence and radiomics in pituitary neuroendocrine and sellar tumors: a quantitative and qualitative synthesis. (cdc.gov)
  • WELIREG was the first HIF-2α inhibitor therapy approved in the U.S. and is currently approved for the treatment of adult patients with von Hippel-Lindau (VHL) disease who require therapy for associated RCC, central nervous system hemangioblastomas, or pancreatic neuroendocrine tumors, not requiring immediate surgery. (metrolatinousa.com)
  • WELIREG (belzutifan) is indicated for the treatment of adult patients with von Hippel-Lindau (VHL) disease who require therapy for associated renal cell carcinoma (RCC), central nervous system (CNS) hemangioblastomas, or pancreatic neuroendocrine tumors (pNET), not requiring immediate surgery. (metrolatinousa.com)
  • Neuroendocrine tumors (NET) of the gallbladder are a rare entity with only 0.2% of all NET located in the gall bladder. (scirp.org)
  • Well-differentiated NETs occur at a relatively lower age group unlike other gallbladder tumors, whereas neuroendocrine carcinoma (NEC) occurs in an older category of patients. (scirp.org)
  • 4. Advances in the diagnosis and treatment of pancreatic neuroendocrine neoplasms in Japan. (nih.gov)
  • Pancreatic cancer risk is elevated in this syndrome, and our case highlights the need for vigilance in screening for pancreatic neoplasms in these patients. (biomedcentral.com)
  • Many retrospective studies have confirmed that capecitabine combined with temozolomide is effective in neuroendocrine neoplasms. (viamedica.pl)
  • Treatment options for grade 3 neuroendocrine neoplasms are limited, and the overall prognosis is better in the subgroup of patients with grade 3 neuroendocrine tumours. (viamedica.pl)
  • It was a retrospective study in the population of patients with diagnosed grade 3 neuroendocrine neoplasms of different origin treated with capecitabine and temozolomide. (viamedica.pl)
  • Neuroendocrine neoplasms of the larynx have been divided into those of epithelial or neural origin. (keyopinionleaders.com)
  • There are now over 500 cases of neuroendocrine neoplasms of the larynx in the literature. (keyopinionleaders.com)
  • 2020). A molecular map of lung neuroendocrine neoplasms. (who.int)
  • Both lesions invaded serosa and lymph nodes metastases were found in 17 of 41 lymph nodes retrieved (one lymph node with neuroendocrine metastatic deposits). (ecancer.org)
  • Determine response rate, duration of response, and patterns of recurrence in patients with primary or metastatic, unresectable cancers of the liver after treatment with isolated hepatic perfusion with melphalan. (knowcancer.com)
  • Measurable metastatic (stage IV) or unresectable non-small cell lung cancer (including but not limited to squamous cell carcinoma, adenosquamous carcinoma, or adenocarcinomas) with at least one lesion that is resectable for TIL generation. (nih.gov)
  • Neeraj Agarwal discusses the phase two LITESPARK-013 trial exploring the efficacy of belzutifan, a hypoxia-inducible transcription factor 2 alpha inhibitor, in treating metastatic renal cell carcinoma. (urotoday.com)
  • Ultimately, the study concludes that the 120 milligram dose of belzutifan is optimal, reaffirming its status as the standard treatment dose for metastatic renal cell carcinoma. (urotoday.com)
  • This is a transcription factor inhibitor, a new class of drug for patients with metastatic renal cell carcinoma. (urotoday.com)
  • And based on the larger LITESPARK-005 trial, which compared belzutifan with everolimus in a randomized fashion in a salvage therapy setting in patients with metastatic clear cell renal cell carcinoma, we expect belzutifan to be approved for a wider patient population who have metastatic renal cell carcinoma. (urotoday.com)
  • Most patients have metastatic disease at presentation, and the prognosis is poor. (msdmanuals.com)
  • Emerging and mechanism-based therapies for recurrent or metastatic Merkel cell carcinoma. (nih.gov)
  • Currently, immune check point inhibitors (ICI) are the first line of treatment for metastatic MCC, but over 50% of patients do not achieve durable responses. (nih.gov)
  • Overall, our studies identified dinaciclib as a promising novel treatment for metastatic MCC and support a clinical trial of this agent in patients whose MCC has progressed despite ICI therapy. (nih.gov)
  • ultrasound in assessing effectiveness of anlotinib in patients with locally advanced, metastatic, or unresectable pheochromocytoma or paraganglioma (PPGL). (centerwatch.com)
  • AIMS: Focal therapy treats individual areas of tumour in non-metastatic prostate cancer in patients unsuitable for active surveillance. (bvsalud.org)
  • MATERIALS AND METHODS: A Markov cohort health state transition model with four health states (stable disease, local recurrence, metastatic disease and death) was created, evaluating costs and utilities over a 10-year time horizon for patients diagnosed with non-metastatic prostate cancer. (bvsalud.org)
  • Focal therapy can be used for the primary treatment of individual areas of cancer in those patients with prostate cancer whose disease has not spread (localized or non-metastatic prostate cancer) and whose disease is unsuitable for active monitoring. (bvsalud.org)
  • Small-cell carcinoma (SCC) of the cervix is an exceptional member of the neuroendocrine group of cervical carcinomas that is frequently intermixed with a non-SCC component in the form of an adenocarcinoma (ADC) or squamous carcinoma. (wikipedia.org)
  • Carcinoembryonic antigen, squamous cell carcinoma antigen, CYFRA 21-1, and neuron-specific enolase in squamous cell lung cancer patients. (nih.gov)
  • Carcinoembryonic antigen (CEA), squamous cell carcinoma antigen (SCC-Ag), and CYFRA 21-1 are the most useful markers for non-small cell lung cancer (NSCLC), but neuron-specific enolase (NSE) is a tumor maker of choice for SCLC. (nih.gov)
  • There are three categories of cervical cancer: squamous tumours, glandular tumours (adenocarcinoma) and other epithelial tumours (adenosquamous carcinoma, neuroendocrine tumours and undifferentiated carcinoma). (esmo.org)
  • Results Twenty-five patients (20 adenocarcinoma, 4 squamous cell carcinoma and 1 large cell carcinoma) were enrolled. (bmj.com)
  • The incidence of distant metastases in head and neck squamous cell carcinoma (SCC) is relatively small in comparison to other malignancies. (keyopinionleaders.com)
  • BACKGROUND: Local and/or regional recurrence and metachronous primary tumor arising in a previously irradiated area are rather frequent events in patients with head and neck squamous cell carcinoma (HNSCC). (keyopinionleaders.com)
  • INTRODUCTION: The purpose of this paper is to determine the optimal elective treatment of the neck for patients with supraglottic and glottic squamous carcinoma. (keyopinionleaders.com)
  • 2021). Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence. (who.int)
  • Predictors of Survival After Head and Neck Squamous Cell Carcinoma in South America: The InterCHANGE Study. (who.int)
  • Adults with advanced renal cell carcinoma (RCC) after failure of treatment with sunitinib or sorafenib. (nih.gov)
  • 1. [Eosinophilic solid and cystic renal cell carcinoma with TSC2 gene mutations in children]. (nih.gov)
  • 2. [Clinicopathologic features of primary renal neuroendocrine carcinoma]. (nih.gov)
  • chromogranin, pancreastatin and serotonin in the management of patients with advanced renal cell carcinoma. (nih.gov)
  • Sunitinib treatment for multifocal renal cell carcinoma (RCC) and pancreatic neuroendocrine tumor (NET) in patient with Von Hippel-Lindau disease. (nel.edu)
  • So for example, hemangioblastoma or some pancreatic neuroendocrine cancers and also VHL associated renal cell carcinoma. (urotoday.com)
  • The patient was a 37-year-old male with a long-standing history of end-stage renal disease. (cytojournal.com)
  • Following assessment of the patient at a tertiary hospital's genetics clinic, a provisional diagnosis of BHD syndrome was made for her bilateral renal cysts and notable skin lesions (biopsy of one of these lesions however was reported as milia). (bmj.com)
  • Individuals are also at increased risk of developing a type of kidney cancer called clear cell renal cell carcinoma . (nccs.com.sg)
  • Renal cell carcinoma is about twice as common in men than in women. (metrolatinousa.com)
  • 2022). The relationship between blood pressure and risk of renal cell carcinoma. (who.int)
  • Morphological findings in frozen non-neoplastic kidney tissues of patients with kidney cancer from large-scale multicentric studies on renal cancer. (who.int)
  • In the RADIANT-3 trial, patients with pNET were randomized to receive everolimus or placebo along with best supportive care. (nih.gov)
  • Everolimus was again associated with improvement in PFS compared to placebo and it has been approved by the FDA for patients with progressive pNET. (nih.gov)
  • While undergoing surveillance with 68 Gallium-DOTATATE positron emission tomography/computed tomography for her PNET, the patient was found to have a large choroid plexus papilloma in her right temporal lobe. (biomedcentral.com)
  • Here we report a patient who initially presented with cystic PNET and later was found to have LFS. (biomedcentral.com)
  • A tumour called a pancreatic neuroendocrine tumour (pNET) can also develop in the pancreas. (nccs.com.sg)
  • Kaplan-Meier survival curves showed that patients with DDC -positive tumours have significantly longer disease-free survival ( P =0.009) and overall survival ( P =0.027). (nature.com)
  • Introduction: The autosomal dominant multiple endocrine neoplasia type 1 (MEN1), characterized by parathyroid hyperplasia (PH), neuroendocrine digestive tumours (NET) and pituitary adenomas (PA), is due to mutations in the tumor suppressor gene MEN1 encoding a 610-amino acid protein, menin. (endocrine-abstracts.org)
  • Most of the studies focused on grade 1 and grade 2 neuroendocrine tumours, mainly of pancreatic origin. (viamedica.pl)
  • There are limited data regarding the efficacy capecitabine with temozolomide in grade 3 neuroendocrine tumours. (viamedica.pl)
  • The new World Health Organisation 2017 classification distinguished well-differentiated grade 3 neuroendocrine tumours from poorly differentiated grade 3 neuroendocrine carcinomas. (viamedica.pl)
  • This study aimed to evaluate response and survival parameters and compare outcomes of treatment of neuroendocrine tumours and carcinomas. (viamedica.pl)
  • The study included 32 patients with grade 3 neuroendocrine tumours treated with capecitabine and temozolomide. (viamedica.pl)
  • The progression-free survival for patients with neuroendocrine tumours was 15.3 months (95% CI: 3.9-30.4), and for patients with neuroendocrine carcinomas it was 3.3 months (95% CI: 2.5-7.1). (viamedica.pl)
  • Median overall survival was 22 months (95% CI: 11.8-22.0) and 4.6 months (95% CI: 2.2-5.9) for patients with tumours and carcinomas, respectively. (viamedica.pl)
  • The safety and effectiveness of TheraSphere will be evaluated in patients with unresectable hepatocellular carcinoma in whom treatment with standard-of-care sorafenib is planned. (mayo.edu)
  • What's new in treating hepatocellular carcinoma, the most common liver cancer? (mdanderson.org)
  • Novel deep learning radiomics model for preoperative evaluation of hepatocellular carcinoma differentiation based on computed tomography data. (cdc.gov)
  • Radiomics in hepatocellular carcinoma: A state-of-the-art review. (cdc.gov)
  • As a result, patients with advanced unresectable NETs have a poor prognosis. (nih.gov)
  • The correlation between the presence of neuroendocrine differentiation in HBCC and patient prognosis should be further studied. (karger.com)
  • High Bcl-2 expression was associated with poor prognosis in EPNEC patients. (ecancer.org)
  • The prognosis of patients with CRC largely depends on the degree of penetration of the tumour through the bowel wall, the nodal status, and the presence or absence of distal metastases ( Steinberg et al, 1986 ). (nature.com)
  • 1 Pathologic assessment of colorectal resection specimens plays a key role in guiding treatment decisions and determining prognosis, with stage being the most powerful predictor of patient outcomes, and specifically survival. (allenpress.com)
  • Unfortunately, these modalities frequently do not provide a durable response, and the prognosis for patients with DSRCT remains poor. (sarcomahelp.org)
  • Patients with advanced RCC whose cancer progresses following immune checkpoint and anti-angiogenic therapies face a poorer prognosis, and for those patients, there is a crucial unmet need for new options with an alternative mechanism of action," said Dr. Marjorie Green, senior vice president and head of late-stage oncology, global clinical development, Merck Research Laboratories. (metrolatinousa.com)
  • Small cell lung cancer (SCLC) and high-grade extrapulmonary neuroendocrine carcinomas (EPNEC) share similar histopathological features and treatment, but outcomes may differ. (ecancer.org)
  • Data from a phase 1 trial highlight a clinically acceptable safety profile for BI 764532 in patients with extensive-stage small cell lung cancer and extrapulmonary neuroendocrine carcinomas. (cancernetwork.com)
  • Pathology examination with immune histochemical marking of surgical specimen came back for a stage 3 (WHO 2010, ENETS 2006) large cell neuroendocrine carcinoma ( Figure 2 ). (scirp.org)
  • Non-Merkel cell carcinoma high-grade neuroendocrine carcinomas were 5 small-cell lung carcinomas, 3 well-differentiated intestinal carcinomas, and 1 high-grade neuroendocrine carcinoma of the cervix. (cdc.gov)
  • Merkel cell carcinoma is a rare, aggressive skin cancer that tends to affect older White people. (msdmanuals.com)
  • Merkel cell carcinoma also affects younger patients who are immunosuppressed. (msdmanuals.com)
  • Although Merkel cell carcinoma can affect any part of the skin, it is most common on sun-exposed areas (eg, face, upper extremities). (msdmanuals.com)
  • Diagnosis of Merkel cell carcinoma is by biopsy. (msdmanuals.com)
  • Treatment of Merkel cell carcinoma is determined by cancer staging and typically includes wide local excision, often followed by radiation therapy, lymph node dissection, or both. (msdmanuals.com)
  • Because Merkel cell carcinoma seems to be related to ultraviolet (UV) exposure, a number of measures are recommended to limit exposure. (msdmanuals.com)
  • Merkel cell carcinoma (MCC) is a deadly skin cancer, and about 80% of its cases have been shown to harbor integrated Merkel polyomavirus in the tumor cell genome. (uni-wuerzburg.de)
  • Viral oncoproteins expressed in the tumor cells are considered as the oncogenic factors of these virus-positive Merkel cell carcinoma (VP-MCC). (uni-wuerzburg.de)
  • Merkel cell carcinoma (MCC) is an aggressive, virus-associated, neuroendocrine tumor of the skin mainly affecting immunocompromised patients. (uni-wuerzburg.de)
  • Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer with a high fatality rate. (nih.gov)
  • Because of the distinct natural history of small cell carcinoma of the uterine cervix, and because patients with this condition are considered to have a systemic disease, the treatment strategies for this disease are different from those of other carcinomas" (ajronline.org). (wikipedia.org)
  • Large-cell carcinoma (LCC), like small-cell carcinoma (SCC) is very rare and only accounts for about 5% of all cervical cancers. (wikipedia.org)
  • Small cell carcinoma of the prostate is a high-grade malignant neoplasm with neuroendocrine differentiation. (medscape.com)
  • Small cell carcinoma of the prostate is rare, accounting for less than 1% of all prostate cancers . (medscape.com)
  • Approximately 50% of patients have pure small cell carcinoma at initial presentation. (medscape.com)
  • [ 3 ] The overall risk of developing prostatic small cell carcinoma increases with age, with disease occurrence typically being in men older than 60 years. (medscape.com)
  • The genetic changes specific to prostatic small cell carcinoma have not been studied in great detail. (medscape.com)
  • There are also rare BCC cases that show neuroendocrine differentiation. (karger.com)
  • Here, we describe a case of HBCC with neuroendocrine differentiation. (karger.com)
  • A HBCC case with neuroendocrine differentiation has not been previously reported. (karger.com)
  • Immunohistochemical analysis generally reveals both epithelial and neuroendocrine differentiation. (medpagetoday.com)
  • Colorectal carcinoma is the fourth most commonly diagnosed cancer in the United States, with the National Cancer Institute Surveillance, Epidemiology, and End Results Program estimating that there will be 149 500 new cases and 52 980 deaths in 2021. (allenpress.com)
  • Accuracy, consistency, and completeness of colorectal cancer staging across institutions provides the foundation for evidence-based patient management decisions. (allenpress.com)
  • The treatment did not overcome the aggressive character of neuroendocrine carcinomas and resulted in low response and survival outcomes in comparison to those achieved in tumour therapy. (viamedica.pl)
  • Patients with peritoneal seeding, unresectable extrahepatic metastases, or unresectable pathologically-involved lymph nodes outside area of portahepatis do not receive treatment. (knowcancer.com)
  • Patients with 3 or fewer brain metastases that are less than 1 cm in diameter and asymptomatic are eligible. (nih.gov)
  • Patients with surgically resected brain metastases are eligible. (nih.gov)
  • Unfortunately, the majority of patients with brain metastases experience cognitive (such as learning and memory) deterioration after WBRT. (mayo.edu)
  • 10,11 More than 40% of patients have distant metastases at the time of diagnosis, mostly located in the liver, lungs, and lymph nodes (Figure 1). (sarcomahelp.org)
  • In the RADIANT-2 trial, everolimus and a somatostatin analog were used in patients with functional NETs and treatment was associated with an an improvement in progression-free survival (PFS). (nih.gov)
  • Of 535 sporadic NETs in the pancreas collected from the NET archives of the departments of pathology in Zurich, Switzerland, and Kiel, Germany, 24 patients (4.5%) suffered from sporadic pancreatic gastrinomas and ZES. (kb.se)
  • Recent studies have shown that Pancreatic neuroendocrine carcinomas (NECs) contain well-differentiated NETs with high proliferative activity (WDNET-G3), as well as poorly differentiated NECs (PDNECs). (enets.org)
  • Recent updates of the World Health Organization classification and grading separate pNETs into 2 broad categories according to the histopathologic criteria, including the Ki-67 proliferative index and mitotic counts: well-differentiated NET and poorly-differentiated neuroendocrine carcinoma (NEC). (nih.gov)
  • The diagnosis of PHNEC was confirmed after histopathologic examination identified neuroendocrine cells, including a positive immunohistochemical staining result. (medscape.com)
  • Aims: Mixed adeno-neuroendocrine carcinoma is a rare entity, diagnosed with immunohistochemical studies. (ogu.edu.tr)
  • Basal cell carcinoma (BCC) is a slow-growing and frequently occurring tumor of the eyelids. (karger.com)
  • Neuroendocrine carcinoma of the cervix is best defined separately:Neuroendocrine: Of, relating to, or involving the interaction between the nervous system and the hormones of the endocrine glands.Carcinoma: An invasive malignant tumor derived from epithelial tissue that tends to metastasize to other areas of the body. (wikipedia.org)
  • The latter consist of paragangliomas while the epithelial origin group can be divided into the typical and atypical carcinoids and small cell neuroendocrine carcinomata, the latter consisting of the oat cell type, the intermediate cell type and the combined cell type. (keyopinionleaders.com)
  • We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. (cancer.org)
  • Epidermal growth factor receptor ( EGFR ) mutations, especially in-frame deletions in exon 19 (DEL) and a point mutation in exon 21 (L858R), predict gefitinib sensitivity in patients with non-small cell lung cancer (NSCLC). (aacrjournals.org)
  • A systematic review of the published medical literature using PubMed and Medline was carried out using the search terms "gallbladder" AND "cancer [OR] carcinoma" with a special emphasis on review articles. (hindawi.com)
  • Risk factors for gallbladder cancer can be divided into four broad categories as annotated in the following list including (1) patient demographics, (2) gallbladder abnormalities, (3) patient exposures, and (4) infections [ 1 , 8 , 9 ]. (hindawi.com)
  • This randomized phase III trial compares memantine hydrochloride and whole-brain radiotherapy with or without hippocampal avoidance in reducing neurocognitive decline in patients with cancer that has spread from the primary site (place where it started) to the brain. (mayo.edu)
  • This randomized phase II/III trial studies how well whole-brain radiation therapy works and compares it with or without hippocampal avoidance in treating patients with small cell lung cancer that is found in one lung, the tissues between the lungs, and nearby lymph nodes only (limited stage) or has spread outside of the lung in which it began or to other parts of the body (extensive stage). (mayo.edu)
  • The purpose of this study of sulfasalazine is to see how well it works in preventing acute diarrhea in patients with cancer who are undergoing pelvic radiation therapy. (mayo.edu)
  • Sulfasalazine may relieve diarrhea in patients with cancer who are undergoing pelvic radiation therapy. (mayo.edu)
  • The association of MCC with a recently discovered polyomavirus, combined with the increased incidence and mortality of MCC among immunocompromised patients, highlight the importance of the immune system in controlling this cancer. (nih.gov)
  • INTERNATIONAL ATOMIC ENERGY AGENCY, PET-CT for the Management of Cancer Patients: a Review of the Existing Evidence, IAEA Human Health Series No. 45, IAEA, Vienna (2023). (iaea.org)
  • To make reliable information more widely available, the IAEA convened an expert consultant group to review, based on the most recent developments of PET radiopharmaceuticals, Human Health Series No. 9, Appropriate Use of FDG-PET for the Management of Cancer Patients. (iaea.org)
  • ESMO Guides for Patients are designed to assist patients, their relatives and caregivers to better understand the nature of different types of cancer and evaluate the best available treatment choices. (esmo.org)
  • Your gift will help support our mission to end cancer and make a difference in the lives of our patients. (mdanderson.org)
  • Background Not all non-small cell lung cancer (NSCLC) patients possess drug-targetable driver mutations, and response rates to immune checkpoint blockade therapies also remain unsatisfactory. (bmj.com)
  • Machine Learning Algorithms for Prediction of Survival Curves in Breast Cancer Patients. (cdc.gov)
  • Risk Assessment of Pulmonary Metastasis for Cervical Cancer Patients by Ensemble Learning Models: A Large Population Based Real-World Study. (cdc.gov)
  • Application of Machine Learning Techniques to Predict Bone Metastasis in Patients with Prostate Cancer. (cdc.gov)
  • A type of pancreatic cancer called pancreatic neuroendocrine tumour can occur. (nccs.com.sg)
  • In the U.S., approximately 15% of patients with kidney cancer are diagnosed at an advanced stage. (metrolatinousa.com)
  • Clinical transition probabilities were derived from prostate cancer registries in patients undergoing radical prostatectomy, EBRT and focal therapy using cryotherapy (Boston Scientific) or high-intensity focused ultrasound (HIFU) (Sonablate). (bvsalud.org)
  • Focal therapy in these patients results in similar control of the cancer to more invasive therapies, such as surgical removal of the prostate and radiotherapy, with the benefit of fewer sexual, urinary and rectal side effects. (bvsalud.org)
  • Previously collected information from people undergoing treatment for their prostate cancer, together with published literature and clinical opinion, was used within the model to predict the treatment pathway, costs incurred and the results of treatment in terms of patient benefits (effectiveness and quality of life). (bvsalud.org)
  • 2003), multi-agent chemotherapy and pelvic radiotherapy before surgery (radical hysterectomy) followed by chemotherapy after surgery produce better outcomes for its patients. (wikipedia.org)
  • This new classification algorithm aims to improve the prediction of the clinical outcomes and survival and help clinicians select better therapeutic strategies for patient care and management. (nih.gov)
  • This applies to about 40% of patients, according to a 2015 review of clinical characteristics and treatment outcomes in 960 patients with advanced SCBC. (medpagetoday.com)
  • Our analysis highlights the presence of larger proportions of SOC patients in the lowest dermatologist-dense areas and this lack of access to dermatologists may contribute to inferior dermatological care and outcomes in Hispanic or Latino, and Black or African American minorities. (cdlib.org)
  • This is a multicentre retrospective analysis of advanced EPNEC and SCLC patients treated with platinum-based chemotherapy. (ecancer.org)
  • EPNEC patients presented inferior RR to platinum-based chemotherapy than SCLC but tended to live longer. (ecancer.org)
  • Treatment: Once their cells have grown, the patients will be admitted to the hospital for the conditioning chemotherapy, the TIL cells and aldesleukin. (nih.gov)
  • 1] Furthermore,early reports from Europe imply that unmanipulated peripheral blood orbone marrow autografts are inadequate, as all of the patients who receivedsuch grafts developed disease recurrence after high-dose chemotherapy. (cancernetwork.com)
  • Although patients with pNEC show variable responses to platinum-based chemotherapy, predictors of the response are unknown. (enets.org)
  • The patient is started on platinum-based chemotherapy for four cycles, but has a poor response and unfortunately dies 3 months later. (medpagetoday.com)
  • Methods NSCLC patients who had undergone at least two regimens of standard chemotherapy for unresectable disease or had had at least one treatment including chemotherapy or radiation for recurrent disease after surgery were enrolled in this open-label, single-arm, multicenter, phase 2 study. (bmj.com)
  • Patients will be treated with 3 cycles of chemotherapy in the induction phase of the study. (who.int)
  • Patient was referred to the oncology department for chemotherapy sessions and subsequent follow up. (scirp.org)
  • Patient underwent 3 cycles of chemotherapy, CDDP (cisplatin) protocol with Etoposide, with no signs of local recurrence until date. (scirp.org)
  • There are two types of neuroendocrine carcinomas of the cervix: small-cell and large-cell. (wikipedia.org)
  • The determination of NSE in NSCLC could allow selection of patients with neuroendocrine features. (nih.gov)
  • A female patient in her 50s, with a medical history of hypercholesterolaemia, osteoporosis, past depressive episodes, recurrent atypical chest pain and mildly dilated aortic root (under surveillance), was investigated for a recurrent bilateral flank pain. (bmj.com)
  • 124 healthy persons and 96 patients with nonmalignant lung disease). (nih.gov)
  • Morphologically and biologically, SCBC is marked by the same rapid progression, early metastasis, and high mortality rates that characterize small cell lung carcinoma. (medpagetoday.com)
  • Clinical data, including patient demographics, baseline laboratory data, tumor characteristics, treatment modalities and outcome, were obtained from a database of enrolled patients. (medscape.com)
  • Patients underwent CT to evaluate disease status and treatment response. (medscape.com)
  • Everolimus tablets are kinase inhibitors indicated for the treatment of adult and pediatric patients aged 1 year and older with TSC who have subependymal giant cell astrocytoma (SEGA) that requires therapeutic intervention but cannot be curatively resected. (nih.gov)
  • These cells are called Tumor Infiltrating Lymphocytes, or TIL and we have given this type of treatment to over 100 patients. (nih.gov)
  • Lesions that have been treated with stereotactic radiosurgery must be clinically stable for 1 month after treatment for the patient to be eligible. (nih.gov)
  • Patients of both genders must be willing to practice birth control from the time of enrollment on this study and for four months after treatment. (nih.gov)
  • Patients who are HIV seropositive can have decreased immune competence and thus may be less responsive to the experimental treatment and more susceptible to its toxicities. (nih.gov)
  • The purpose of this long term registry study is to collect and analyze information from patients being treated with various forms of radiation therapy to improve the treatment of future patients. (mayo.edu)
  • Althoughthere is evidence that allogeneic transplantation can lead to long-termdisease remissions in patients with aplastic anemia and coincidental autoimmunedisease, given the 20% to 30% treatment-related mortality, it is unlikelythat this approach can be justified for the majority of patients with autoimmunedisease. (cancernetwork.com)
  • In addition, inpatient treatment is time-and cost-intense, conflicting with the actual burst of health expenses and with patient preferences. (uni-wuerzburg.de)
  • Patients receiving BioLogicals produced the overall highest costs, whereas outpatient treatment with classic systemic antipsoriatic medications was less cost-intense than other alternatives. (uni-wuerzburg.de)
  • Each patient should be evaluated thoroughly and discussed individually by a multidisciplinary and dedicated NET-expert team, which might consider all treatment options, including ongoing clinical trials before selecting the appropriate treatment sequence. (nih.gov)
  • eGERD patients with mild mucosal injury whose symptoms were under control and who were on maintenance therapy with acid-suppressive drugs were withdrawn from the drug treatment for 4 weeks. (researchsquare.com)
  • Since both drugs were administered to about the same number of patients though incidentally, we examined the relationship between patient background factors and symptom relapse/non-relapse by treatment group. (researchsquare.com)
  • Background: Immunocompromised patients, including those with human immunodeficiency virus (HIV), have been observed to have verrucae that are more extensive and treatment-resistant compared to those in immunocompetent patients. (cdlib.org)
  • LITESPARK-005 is a randomized, open-label Phase 3 trial (ClinicalTrials.gov, NCT04195750 ) evaluating WELIREG compared to everolimus for the treatment of patients with advanced RCC that has progressed after prior treatment with PD-1/L1 and VEGF-TKI therapies, in sequence or in combination. (metrolatinousa.com)
  • Thus, elucidating the mechanisms for autoantibody access to the CNS may provide a wider spectrum of treatment options for patients with these complex and puzzling disorders. (frontiersin.org)
  • PURPOSE: In older patients who do not wish to undergo watchful waiting, focal therapy could be an alternative to the more morbid radical treatment. (bvsalud.org)
  • MATERIALS AND METHODS: A total of 649 patients across 11 UK sites receiving focal high-intensity focused ultrasound or cryotherapy between June 2006 and July 2020 reported within the UK-based HEAT (HIFU Evaluation and Assessment of Treatment) and ICE (International Cryotherapy Evaluation) registries were evaluated. (bvsalud.org)
  • Patients who can be assigned to a specific subset of CUP for which a specific treatment is recommended by the 2015 ESMO Clinical Practice Guidelines for CUP or with a clinical and IHC profile indicative of a specific primary tumor are also excluded. (who.int)
  • How far to extend the surgical treatment of papillary thyroid carcinoma (PTC) is still an open question. (keyopinionleaders.com)
  • The model showed that focal therapy using either cryotherapy or HIFU was associated with a lower overall cost and higher patient benefit than either surgery or radiotherapy, indicating that focal therapy represents good value for money in the NHS. (bvsalud.org)
  • If hepatitis C antibody test is positive, then patient must be tested for the presence of antigen by RTPCR and be HCV RNA negative. (nih.gov)
  • In its early stages, neuroendocrine carcinoma is asymptomatic (not showing or producing indications of a disease or other medical condition). (wikipedia.org)
  • From July, 2006 to July, 2014, 142 patients were identified, being 82 (57.7%) SCLC and 60 (42.3%) EPNEC. (ecancer.org)
  • The aim is to examine the relationship of the changes in the frequency and severity of gastrointestinal symptoms after discontinuation of acid-secretion inhibitors for erosive GERD (eGERD) with possible patient background factors, and to identify factors that influence these changes. (researchsquare.com)
  • My sister was diagnosed yesterday with Neuroendocrine Carcinoma found in the colon and we are trying to hit the ground running on where she should go. (cancer.org)
  • Pathology findings on surgical specimen came back for neuroendocrine tumour. (scirp.org)
  • All patients must have had at least one appropriate first line systemic therapy and progressed. (nih.gov)
  • Motivated patients might benefit from psychological approaches corresponding to psychotherapy, hypnotherapy, cognitive behavioral therapy, or leisure remedy. (dnahelix.com)
  • To determine the response rates and toxicity in patients that have undergone skin directed radiation therapy for inflammatory cutaneous dermatoses. (mayo.edu)
  • The article by Dr. Burt provides an excellent summary of the rationale for using high-dose therapy with autologous or allogeneic bone marrow transplantation (BMT) in patients with severe autoimmune diseases (SADS). (cancernetwork.com)
  • In patients with gastroesophageal reflux disease (GERD) on maintenance therapy with acid-suppressive drugs, it is not clear what background factors allow patients to discontinue the drugs. (researchsquare.com)
  • Autologous Vγ9Vδ2 T-cell therapy was administered to all 25 patients, of which 16 completed the foreseen course of 6 injections of cultured cells. (bmj.com)
  • We evaluated the role of focal therapy in patients 70 years and older as an alternative management modality. (bvsalud.org)
  • The patient denied any of the following symptoms including hypoglycemia, night sweats, diarrhea, or weight loss. (cytojournal.com)
  • In unresectable patients, the goals of these therapies are to palliate the tumor-related symptoms and prolong the lifespan. (nih.gov)
  • What are the symptoms that patients with VHL may have? (nccs.com.sg)
  • Facebook can be an effective ancillary tool for facilitating patient-oriented research in rare diseases. (jmir.org)
  • Challenges in recruiting patients into rare disease clinical studies contribute to wide knowledge gaps in understanding disease pathogenesis, natural history, and optimal therapeutic approaches. (jmir.org)
  • A case of phaeochromocytoma in a female patient in her 50s with phenotypical expressions for the rare Birt-Hogg-Dubé (BHD) syndrome is presented. (bmj.com)
  • Introduction: Insulinoma is a rare neuroendocrine tumor. (endocrine-abstracts.org)
  • The aim of our study is to discuss the current level of evidence regarding this pathological entity by means of a rare case report on a neuroendocrine carcinoma of the gall bladder in a 63-year-old patient with a history of diabetes. (scirp.org)
  • In our study, we aimed to report a case series from a tertiary hospital with demographics of the patients, detailed tumor and clinical findings and follow-up plus survival conditions. (ogu.edu.tr)
  • Most patients have multifocal disease but also have a dominant nodule located in the peripheral zone. (medscape.com)