• Advances in treatment have dramatically changed the lives of many patients, their loved ones, and their caregivers by restoring patients to health and delaying death, even restoring to some the expectation of having an average lifespan. (ucsf.edu)
  • Patients, caregivers and providers may register online or by contacting the Helpline toll free at (800) 500-9976 or by email at [email protected] . (lymphoma.org)
  • Learn about the FDA Patient Representative Program and the Patient Engagement Collaborative to see how patients and caregivers are working with the FDA to have their voice included in medical product approvals and FDA policy. (fda.gov)
  • Read FDA Federal Register Notices and submit your comments on current FDA draft guidances and other policy related questions that affect patients and caregivers. (fda.gov)
  • While some of the symptoms of hyperthyroidism and hypothyroidism are similar to those in younger patients, it is not uncommon for both hyperthyroidism and hypothyroidism to be manifest in subtle ways in older patients, often masquerading as diseases of the bowel or heart or a disorder of the nervous system. (thyroid.org)
  • However, while the younger patient often has multiple symptoms related to the overactive thyroid, the elderly patient may only have one or two symptoms. (thyroid.org)
  • Other patients may also have few symptoms, such as patient number 6, whose main symptoms are depression and tremor. (thyroid.org)
  • Symptoms of hyperthyroidism may be brought under control with adjunctive medications, such as beta-adrenergic blockers (propranolol [Inderal®], metoprolol [Lopressor ®]), which are often given to slow a rapid heart rate, although they must be given with caution in the patient with co-existing congestive heart failure and the dose should be reduced once thyroid function is controlled in the normal range. (thyroid.org)
  • Symptoms such as constipation and fecal incontinence are among the most disruptive physical problems for systemic sclerosis patients, and we really don't know the cause of them at this point. (sclerodermanews.com)
  • Researchers found an enrichment of bacteria species Erwinia and Trabulsiella in systemic sclerosis patients with the most severe symptoms, suggesting that "not only are there differences in the microbiota composition between systemic sclerosis patients and healthy controls, but these differences may contribute to clinical symptoms," Dr. Volkmann explained . (sclerodermanews.com)
  • Patients must be at least 18 years of age and not older than 75 years of age at the time of enrollment. (clinicaltrials.gov)
  • Patients must have completed a stem cell transplant regimen for newly diagnosed multiple myeloma (MM) consisting of (at least) induction chemotherapy and single or tandem autologous stem cell transplant (ASCT) within eight months of study enrollment. (clinicaltrials.gov)
  • To date, more than 270 patients in seven countries in North America, Europe, Asia, and Australia have received the experimental therapy. (sciencecodex.com)
  • The Wordspy entry for this phrase is as follows : There are multiple factors that are contributing to the orphan patient problem in North America. (wikipedia.org)
  • Most patients fulfilled criteria for non-amnestic/dysexecutive mild cognitive impairment, even if some cognitive deficits seemed unusually severe. (nih.gov)
  • Forty-eight patients from two independent cohorts fulfilling the Canada 2003 criteria for ME/CFS were evaluated with respect to cytotoxic lymphocyte phenotype and function. (frontiersin.org)
  • We put our patients' priorities at the center of our care, and strive for breakthrough discoveries so that we can improve people's lives. (ucsf.edu)
  • How a financially sagging hospital revived itself with a customer service approach that makes patients and employees its top priorities. (shrm.org)
  • A global, multi-center trial found almost half of patients with slow growing lymphomas had complete responses to the antibody called mosunetuzumab. (sciencecodex.com)
  • Stem cell transplant patients or those who have a blood (hematologic) cancer such as leukemia, lymphoma, or myeloma may have different risks for fungal infections. (cdc.gov)
  • Please see Stem Cell Transplant Patients and Fungal Infections for more information. (cdc.gov)
  • The overall cohort included patients whose disease had progressed after stem cell transplant, as well as those whose disease did not respond to or relapsed after CAR T. (sciencecodex.com)
  • This study will evaluate a treatment regimen that alternates two different 3-drug regimens every eight weeks for patients that have previously completed autologous stem cell transplant. (clinicaltrials.gov)
  • In addition, HIV infection continues to be a highly prevalent and rapid killer in low- and middle-income countries, where ART is unavailable to 70-80% of patients for whom it might be beneficial. (ucsf.edu)
  • Long-term follow-up of cognitive dysfunction in patients with aluminum hydroxide-induced macrophagic myofasciitis (MMF). (nih.gov)
  • Affected patients are middle-aged adults, mainly presenting with diffuse arthromyalgias, chronic fatigue, and cognitive dysfunction. (nih.gov)
  • According to a study recently presented at the Annual European Congress of Rheumatology (EULAR) , Rome, patients with systemic sclerosis harbor a unique microbiome in their gut when compared to healthy individuals, which may contribute to patients' immune dysfunction. (sclerodermanews.com)
  • As a cancer patient, you may have received a lot of information about your treatment and your journey to recovery. (cdc.gov)
  • Specifically, the Complainant alleges that Charlwell refused to accept a patient for treatment at its facility because that patient was being treated with Suboxone, a medication used to treat Opioid Use Disorder (OUD). (ada.gov)
  • One of the benefits of this treatment is that it's 'off-the-shelf,' meaning it does not need to be manufactured for each patient. (sciencecodex.com)
  • In four patients whose disease came back after remission, three saw a response when they started treatment again. (sciencecodex.com)
  • Further, in some of the patients who had previously received CAR T therapy, molecular testing showed the CAR T cells in their bodies increased in number in their blood after treatment with mosunetuzumab. (sciencecodex.com)
  • As with younger patients, treatment of hyperthyroidism in the older patient includes antithyroid drugs and radioactive iodine (see Hyperthyroidism brochure ). (thyroid.org)
  • Once thyroid function is maintained in the normal range with oral medication, the doctor and patient can make a decision on definitive treatment with radioactive iodine together. (thyroid.org)
  • Treatment of an underactive thyroid condition (hypothyroidism) is usually more straightforward than the problem of recurrent hyperthyroidism in the older patient, because of the effect hyperthyroidism can have on the heart, as indicated above. (thyroid.org)
  • Intercept was founded on the belief that targeting FXR would benefit patients with liver diseases for which there are limited or no treatment options, and Ocaliva's approval marks the culmination of more than a decade of work," said Mark Pruzanski, M.D., Chief Executive Officer and President of Intercept. (globenewswire.com)
  • Ocaliva fills an important unmet need for the many patients with PBC who have an inadequate response to or are intolerant of UDCA, which until now has been the only approved treatment," said John Vierling, M.D., F.A.C.P., F.A.A.S.L.D., Professor of Medicine and Surgery at Baylor College of Medicine and Past President of the American Association for the Study of Liver Diseases (AASLD). (globenewswire.com)
  • Through Interconnect, dedicated Care Coordinators will guide patients through disease education, treatment support and, for eligible patients, financial assistance options, which may include reimbursement support, co-pay assistance or access to Ocaliva at no cost. (globenewswire.com)
  • However, some patients still relapse early during maintenance treatment meaning that better options are still needed. (clinicaltrials.gov)
  • Typically a patient's bill of rights guarantees patients information, fair treatment, and autonomy over medical decisions, among other rights. (wikipedia.org)
  • The book describes each of five patients through their hospital experience and the context of their treatment. (wikipedia.org)
  • Regardless of the degree of resource availability within a given setting, the roles of pain and symptom management, psychosocial and spiritual support for patient and loved ones, and retention of hope for a peaceful and dignified death remain as vital as they were in the early days of the epidemic. (ucsf.edu)
  • The 828-bed facility was far below par in numbers of patients served and levels of worker retention. (shrm.org)
  • ORLANDO - A new, experimental immunotherapy can put patients with B-cell non-Hodgkin lymphoma (NHL) that is resistant to or has come back after multiple other therapies, including CAR T therapy, into remission. (sciencecodex.com)
  • The five patients were Ralph Orlando, a construction worker seriously injured in a scaffold collapse, John O'Connor, a middle aged dispatcher suffering from fever that has reduced him to a delirious wreck, Peter Luchesi, a young man who severs his hand in an accident, Sylvia Thompson, an airline passenger who suffers chest pains, and Edith Murphy, a mother of three who is diagnosed with a life-threatening disease. (wikipedia.org)
  • Among patients with slower growing lymphomas, 42 (63 percent) saw a decrease in cancer, and 29 (43 percent) achieved complete remission. (sciencecodex.com)
  • Even with our small sample size, there were still statistically significant differences, including [in systemic sclerosis patients] a decrease in normal, healthy bacteria and an increase in more pathogenic bacteria that in other disease states cause inflammation. (sclerodermanews.com)
  • Reproducible differences between patients and controls were not found in cytotoxic lymphocyte numbers, cytotoxic granule content, activation status, exocytotic capacity, target cell killing, or cytokine production. (frontiersin.org)
  • In addition, supervised dimensionality reduction analyses of the full, multidimensional datasets did not reveal any reproducible patient/control discriminators. (frontiersin.org)
  • Surgery is rarely recommended due to increased operative risks in the older patient. (thyroid.org)
  • Notably, they found that systemic sclerosis patients surprisingly were also enriched in two bacteria species usually found in healthy individuals, Lactobacillus and Bifidobacterium , which are usually reduced in inflammatory diseases patients. (sclerodermanews.com)
  • For example, New England Journal of Medicine mentioned patients with orphan diseases as orphan patients in 1988: N Engl J Med. (wikipedia.org)
  • Older medical references mention the term 'orphan patient' using a different definition, specifically patients with an orphan disease. (wikipedia.org)
  • Cytokine-release syndrome (CRS), a toxicity known to be associated with cellular therapies, was reported in 29 percent of patients on this study. (sciencecodex.com)
  • A new study published in Seizure gives insight into the short-term outcome of patients treated for status epilepticus in Kuopio University Hospital in Finland. (sciencecodex.com)
  • The study, conducted by the University of Eastern Finland and the Epilepsy Centre in Kuopio University Hospital, enrolled 137 status epilepticus patients during 2015. (sciencecodex.com)
  • Fourteen patients were enrolled twice because of another episode of status epilepticus during the study period. (sciencecodex.com)
  • The analysis by researchers at UC San Francisco, Stanford University and UC Berkeley found that discrimination reported by black patients declined significantly over the six-year study period, reducing the difference between blacks and whites from 8.2 percent to 2.5 percent. (ucsf.edu)
  • Researchers said all the groups in the study - black, white and Hispanic - reported high rates of discrimination for one reason or another, and they urged continued monitoring of patients' experiences, since reported discrimination is associated with worse health, lower satisfaction with health care and lower utilization of health services. (ucsf.edu)
  • one patient (1%) in the titration group discontinued from the study due to pruritus. (globenewswire.com)
  • In this study, researchers at the University of California, Los Angeles (UCLA) studied the microbial communities (microbiome) present in the gut of 17 patients with systemic sclerosis and compared the microbial identity with those of 17 healthy individuals. (sclerodermanews.com)
  • Eli Lilly and Company announced that a U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) voted 6-5 that CYRAMZA (ramucirumab) plus erlotinib demonstrated a favorable benefit/risk profile for patients with untreated metastatic EGFR-positive non-small cell lung cancer (NSCLC), based on the results of the positive Phase 3 RELAY study. (pharmaceutical-business-review.com)
  • Almost one in five older patients with a chronic disease reported experiencing health care discrimination of one type or another in a large national survey that asked about their daily experiences of discrimination between 2008 and 2014. (ucsf.edu)
  • The team discovered that systemic sclerosis patients' microbiomes are enriched by inflammatory bacteria while protective bacteria were reduced, with systemic sclerosis patients exhibiting a microbiota flora similar to patients with Crohn's disease (a type of inflammatory bowel disease, characterized by chronic inflammation at the digestive tract). (sclerodermanews.com)
  • Although both bills would have provided patients key rights, such as prompt access to emergency care and medical specialists, only the Senate-passed measure would provide patients with adequate means to enforce their rights. (wikipedia.org)
  • Pharma Company-1's Fentanyl Spray was approved by the FDA in or about January 2012, solely for the management of breakthrough pain in cancer patients who are already receiving and who are tolerant to opioid therapy for their underlying persistent pain. (justice.gov)
  • In health care, an orphan patient is a patient who has been "lost" within the system or has no primary provider overseeing their care. (wikipedia.org)
  • The view from insiders and health care providers is that orphan patients tend to receive inferior care compared to those who have a "gatekeeper" coordinating the medicine. (wikipedia.org)
  • While Graves' disease is still a common cause of hyperthyroidism, toxic nodular goiter is seen more frequently in the older patient. (thyroid.org)
  • During therapy, the effects of change in thyroid function on other body systems must be closely monitored, due to an increased likelihood of co-existing cardiac, central nervous system and thyroid disease in older patients. (thyroid.org)
  • An isolated low TSH is particularly common in older patients. (thyroid.org)
  • Thus, orphan patients are sometimes referred to as "no-family-doctor" patients. (wikipedia.org)
  • Shelley WB, Shelley ED. Publication Types: Letter PMID 3344016 Solutions to the orphan patient problem are complex, as expected due to its multifactorial origins. (wikipedia.org)
  • Before his hip replacement surgery, the patient had been working full time and enjoyed excellent general health, apart from pain and stiffness in his right hip secondary to osteoarthritis. (mja.com.au)
  • For the patients who saw their disease disappear entirely, the remissions appear to be long-lasting. (sciencecodex.com)
  • At a median follow up of six months, 24 of the 29 (83 percent) slow-growing lymphoma patients and 17 of the 24 (71 percent) aggressive lymphoma patients were still disease free. (sciencecodex.com)
  • An important clue to the presence of thyroid disease in an elderly patient is a history of thyroid disease in another close family member such as a brother, sister or child of the patient. (thyroid.org)
  • There is still a large need for new treatments in relapsed or refractory cases, since some patients fail CAR T and others are too sick to wait for cell manufacturing," Schuster said. (sciencecodex.com)
  • There is some controversy about what the normal level of TSH is for elderly patients. (thyroid.org)
  • In general, an attempt is made to render thyroid function either normal or low in an elderly patient treated with radioactive iodine. (thyroid.org)
  • The outcome was assessed at one month after hospital discharge by means of a phone interview and a patient record review. (sciencecodex.com)
  • Find out more about new cancer-related drug approvals, and learn what FDA is doing to bring the patient perspective into the review of new drugs to treat or prevent cancer. (fda.gov)
  • FDA brings the patient perspective into the review of medical products that treat Cancer, Hepatitis B & C and HIV. (fda.gov)
  • Infectious patients cough up huge numbers of mycobacteria, which can survive in the environment for long periods of time. (patient.info)
  • Patients 1, 3 and 6 have hyperthyroidism, that is, excessive production of thyroid hormone by their thyroid glands. (thyroid.org)
  • Patients 2, 4 and 5 have hypothyroidism, or reduced production of thyroid hormone. (thyroid.org)
  • Hypothyroidism is very common in patients over 60 years of age and steadily increases with age (see Hypothyroidism brochure ). (thyroid.org)
  • Intercept is dedicated to helping ensure that people with PBC can access Ocaliva and has launched Interconnect™, a comprehensive and personalized patient support services program. (globenewswire.com)
  • This includes one patient who went back into a remission that has now been ongoing for 13 months. (sciencecodex.com)
  • Pain is underrecognized and undertreated in as many as 60-85% of HIV patients in the developed world. (ucsf.edu)
  • Scientists are still learning about which patients are at highest risk and how to best prevent fungal infections. (cdc.gov)
  • At UC San Francisco, we are driven by the idea that when the best research, the best teaching and the best patient care converge, we can deliver breakthroughs that help heal the world. (ucsf.edu)
  • At 8-week follow-up after the revision surgery, the patient felt much improved. (mja.com.au)