G1 PhaseS PhaseLeechesCell CycleMimosineCyclin-Dependent Kinase Inhibitor p21Cell Line, TumorG1 Phase Cell Cycle CheckpointsCyclin-Dependent Kinase Inhibitor p27Tumor Cells, CulturedLeukemia P388Cell DivisionCyclinsCell LineCell Cycle ProteinsCell ProliferationApoptosisMultiple MyelomaDrug ResistanceCell SurvivalCyclin-Dependent Kinase 2Cyclin-Dependent KinasesLeukemia, ExperimentalCyclin D1Retinoblastoma ProteinProto-Oncogene Proteins c-mycGene Expression Regulation, NeoplasticTumor Suppressor Protein p53Cyclin ETransfectionCDC2-CDC28 KinasesPhosphorylationAntineoplastic AgentsCells, CulturedDrug Resistance, NeoplasmInterneuronsRNA, Small InterferingBlotting, WesternProtein-Serine-Threonine KinasesSignal TransductionCell DifferentiationMutationFlow CytometryMolecular Sequence DataDNA-Binding ProteinsDose-Response Relationship, DrugTumor Suppressor ProteinsRNA, MessengerDNANeuronsDNA DamageProto-Oncogene ProteinsEnzyme InhibitorsMice, NudeInsulin-Like Growth Factor ITime FactorsNeoplasm ProteinsCell Transformation, NeoplasticBase SequenceGene Expression RegulationTranscription FactorsFibroblastsProtein BindingEnzyme ActivationCell NucleusTranscription, GeneticPhenotypeDown-RegulationAmino Acid SequenceImmunohistochemistryBreast NeoplasmsMice, Inbred BALB CAction Potentials